CO2024000198A2 - Composiciones farmacéuticas de un anticuerpo contra pd-1 y uso de las mismas - Google Patents
Composiciones farmacéuticas de un anticuerpo contra pd-1 y uso de las mismasInfo
- Publication number
- CO2024000198A2 CO2024000198A2 CONC2024/0000198A CO2024000198A CO2024000198A2 CO 2024000198 A2 CO2024000198 A2 CO 2024000198A2 CO 2024000198 A CO2024000198 A CO 2024000198A CO 2024000198 A2 CO2024000198 A2 CO 2024000198A2
- Authority
- CO
- Colombia
- Prior art keywords
- pharmaceutical compositions
- antibody against
- retifanlimab
- cancer
- treatment
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39591—Stabilisation, fragmentation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2818—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Dermatology (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163220006P | 2021-07-09 | 2021-07-09 | |
| PCT/US2022/034493 WO2023283049A1 (en) | 2021-07-09 | 2022-06-22 | Pharmaceutical compositions of a pd-1 antibody and use of the same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CO2024000198A2 true CO2024000198A2 (es) | 2024-02-05 |
Family
ID=82608118
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CONC2024/0000198A CO2024000198A2 (es) | 2021-07-09 | 2024-01-11 | Composiciones farmacéuticas de un anticuerpo contra pd-1 y uso de las mismas |
Country Status (17)
| Country | Link |
|---|---|
| US (2) | US12364756B2 (https=) |
| EP (1) | EP4366692A1 (https=) |
| JP (1) | JP2024525566A (https=) |
| KR (1) | KR20240035533A (https=) |
| CN (1) | CN118215465A (https=) |
| AR (1) | AR126404A1 (https=) |
| AU (1) | AU2022307332A1 (https=) |
| CA (1) | CA3224640A1 (https=) |
| CL (1) | CL2024000077A1 (https=) |
| CO (1) | CO2024000198A2 (https=) |
| CR (1) | CR20240065A (https=) |
| EC (1) | ECSP24008791A (https=) |
| IL (1) | IL309985A (https=) |
| MX (1) | MX2024000268A (https=) |
| PE (1) | PE20240797A1 (https=) |
| TW (1) | TW202308694A (https=) |
| WO (1) | WO2023283049A1 (https=) |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SI1478394T1 (sl) * | 2002-02-27 | 2008-12-31 | Immunex Corp | STABILIZIRAN TNFR-Fc SESTAVEK Z ARGININOM |
| HUE068868T2 (hu) * | 2015-07-30 | 2025-02-28 | Macrogenics Inc | PD-1-hez kötõdõ molekulák és alkalmazásukra szolgáló eljárások |
| JOP20190260A1 (ar) * | 2017-05-02 | 2019-10-31 | Merck Sharp & Dohme | صيغ ثابتة لأجسام مضادة لمستقبل الموت المبرمج 1 (pd-1) وطرق استخدامها |
| CN114632150B (zh) * | 2017-11-02 | 2023-12-19 | 正大天晴药业集团股份有限公司 | 一种抗pd-l1人源化单克隆抗体的药物组合物 |
| IL277095B2 (en) * | 2018-03-07 | 2025-10-01 | Pfizer | Preparations containing anti-PD-1 antibody |
| CN110404066B (zh) * | 2018-04-28 | 2022-06-17 | 齐鲁制药有限公司 | 一种抗人pd-1的单克隆抗体制剂、联合用药物及其用途 |
| KR20220044527A (ko) | 2019-08-01 | 2022-04-08 | 인사이트 코포레이션 | Ido 억제제의 투여 요법 |
| KR20220041099A (ko) | 2019-08-05 | 2022-03-31 | 오노 야꾸힝 고교 가부시키가이샤 | 면역 체크포인트 저해약의 유효성 판정 바이오마커 |
-
2022
- 2022-06-22 CA CA3224640A patent/CA3224640A1/en active Pending
- 2022-06-22 KR KR1020247004643A patent/KR20240035533A/ko active Pending
- 2022-06-22 PE PE2024000052A patent/PE20240797A1/es unknown
- 2022-06-22 MX MX2024000268A patent/MX2024000268A/es unknown
- 2022-06-22 AU AU2022307332A patent/AU2022307332A1/en active Pending
- 2022-06-22 CN CN202280059325.XA patent/CN118215465A/zh active Pending
- 2022-06-22 CR CR20240065A patent/CR20240065A/es unknown
- 2022-06-22 IL IL309985A patent/IL309985A/en unknown
- 2022-06-22 EP EP22744039.3A patent/EP4366692A1/en active Pending
- 2022-06-22 WO PCT/US2022/034493 patent/WO2023283049A1/en not_active Ceased
- 2022-06-22 US US17/847,094 patent/US12364756B2/en active Active
- 2022-06-22 JP JP2024500249A patent/JP2024525566A/ja active Pending
- 2022-07-05 TW TW111125067A patent/TW202308694A/zh unknown
- 2022-07-07 AR ARP220101785A patent/AR126404A1/es unknown
-
2024
- 2024-01-09 CL CL2024000077A patent/CL2024000077A1/es unknown
- 2024-01-11 CO CONC2024/0000198A patent/CO2024000198A2/es unknown
- 2024-02-02 EC ECSENADI20248791A patent/ECSP24008791A/es unknown
-
2025
- 2025-07-21 US US19/275,898 patent/US20250345422A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| AR126404A1 (es) | 2023-10-11 |
| PE20240797A1 (es) | 2024-04-18 |
| CL2024000077A1 (es) | 2024-08-23 |
| ECSP24008791A (es) | 2024-03-01 |
| MX2024000268A (es) | 2024-01-31 |
| US20230025464A1 (en) | 2023-01-26 |
| WO2023283049A1 (en) | 2023-01-12 |
| IL309985A (en) | 2024-03-01 |
| CR20240065A (es) | 2024-04-08 |
| KR20240035533A (ko) | 2024-03-15 |
| CN118215465A (zh) | 2024-06-18 |
| TW202308694A (zh) | 2023-03-01 |
| EP4366692A1 (en) | 2024-05-15 |
| AU2022307332A1 (en) | 2024-01-18 |
| US12364756B2 (en) | 2025-07-22 |
| CA3224640A1 (en) | 2023-01-12 |
| JP2024525566A (ja) | 2024-07-12 |
| US20250345422A1 (en) | 2025-11-13 |
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