CN86203106U - Rolling ball blood coagulation time assaying instrument - Google Patents
Rolling ball blood coagulation time assaying instrument Download PDFInfo
- Publication number
- CN86203106U CN86203106U CN 86203106 CN86203106U CN86203106U CN 86203106 U CN86203106 U CN 86203106U CN 86203106 CN86203106 CN 86203106 CN 86203106 U CN86203106 U CN 86203106U CN 86203106 U CN86203106 U CN 86203106U
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- CN
- China
- Prior art keywords
- sample cup
- blood
- time
- blood coagulation
- pellet
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- Ceased
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Abstract
The utility model discloses a rolling ball blood coagulation time assaying instrument uses a magnetic sensor to measure the time of blood clotting, comprising a nonmagnetic material sample cup, a motor, a ferromagnetic substance pellet, a magnetic sensor, and a corresponding electronic control device. The sample cup is arranged on the inclined central shaft of the motor and does the single speed rotating movement, a pellet and a sample ready to measure is arranged on the inner of the sample cup. The pellet is stagnated on the lower side of the sample cup owing to the self weight. After the coagulant is injected into the blood, the pellet is stuck and moved by the blood when the blood clotting takes place, and then, the magnetic sensor detects the movement state of pellet and measures the time of blood clotting which is the time difference between the time of the coagulant injection and the occurrence time of the blood clotting.
Description
The present invention is a kind of in order to measure the instrument of blood coagulation time.
At present domestic each hospital carries out every coagulation indexes most of manual time keeping, macroscopic method of adopting when measuring.Measure the blood clotting index in this way, its conventional efficient is low, reliability and poor repeatability, and labor intensity is big, can't normally carry out the work of blood coagulation mensuration to have caused a considerable amount of hospitals, particularly blood clotting can't be measured and carry out as the routine test project.It is China's first generation blood coagulation analyzer that blade method blood coagulation analyzer has been developed in 8 or two years Shanghai, adopt photometry to measure the blood coagulation situation more widely in the external prior art, no matter but be the blade method, still all there is complex structure in photometry, the problem of aspects such as cost height, and make this method of testing can not be applied to whole blood assay owing to these methods in fact all need to use the optical transmission reaction, this is restricted with regard to the form that makes sample to be tested.
Task of the present invention be propose a kind of simple in structure, and with existing technical device to compare cost lower, better performances, and can carry out the instrument that blood coagulation time is measured to whole blood.
Blood coagulation time determining instrument of the present invention is referred to as bobbin type blood coagulation analyzer, can be by the sample cup, motor, bead Magnetic Sensor and corresponding with it electronic-controlled installation are finished, it is characterized in that nonmagnetic sample cup places with on the certain speed motor rotating central shaft, the motor center axle is offset from perpendicular at a certain angle, be placed with a ferromagnetics bead and blood sample to be measured in the sample cup, bead is trapped in the downside of sample cup owing to deadweight generally speaking, in sample cup blood, inject clotting reagent after a period of time, blood solidifies, blood viscosity sharply rises, thereby make bead be made it to be subjected to displacement by the adhesion of high viscosity blood, place glass displacement that the Magnetic Sensor in the outside is measured bead at once, and the control timer, the time between calculating adding reagent moves to bead like this is exactly the time of blood coagulation.
Solution of the present invention can further describe with accompanying drawing.(seeing accompanying drawing)
1. motor center axles among the figure, offset from perpendicular, general 10～25 ° of its angle, and rotate with the certain speed constant speed.
2. ferromagnetics bead, as steel ball, its diameter is 2.5～3 millimeters.
3. Magnetic Sensor, probe faces bead.
4. calorstat is so that sample remains in the temperature of requirement.
5. the sample cup of being made by nonmagnetic substance can be made with plastics.
6. blood sample to be measured is below the 1ml.
During mensuration, the motor center axle drives the sample cup for liquid synchronous rotary with the certain speed constant speed rotary, this moment, blood not yet condensed, viscosity is littler, bead is trapped in the lower-left side (such as figure) of sample cup for liquid all the time owing to its deadweight, drip in the blood sample can make the reagent of blood generation freezing action after, namely record drips the reagent time. After after a while, blood solidifies (the time generation difference that the difference that the inner composition of blood consists of will make blood clotting take place under the effect of clotting reagent, this in fact also is the purpose of measuring the blood clotting time), at this moment the viscosity of blood sharply rise (approximately viscosity increase decades of times more than), make it to rotate with cup and cling bead, namely departed from original lower-left side position, place this moment the Magnetic Sensor outside the sample cup for liquid just to measure immediately bead and depart from mobile situation, then control timer, time calculating is subjected to displacement to bead from the adding clotting reagent, be the blood clotting time of this sample, then can declare according to the blood clotting time pathological change that this sample blood etc.
Claims (4)
1, a kind of bobbin type blood coagulation analyzer that constitutes by sample cup, motor, bead, Magnetic Sensor and corresponding with it electronic-controlled installation in order to the mensuration blood coagulation time, it is characterized in that the sample cup places with on the certain speed motor rotating central shaft, motor center axle offset from perpendicular, be placed with a bead in the sample cup, the sample cup outside is provided with Magnetic Sensor near the bead place.
2, according to the bobbin type blood coagulation analyzer of claim 1, it is characterized in that motor center axle offset from perpendicular axle, its deviation angle is 10～25 degree.
3,, it is characterized in that the sample cup made by namagnetic substance according to the bobbin type blood coagulation analyzer of claim 1.
4,, it is characterized in that the bead that the sample cup is placed is to be made by ferromagnetics material according to the bobbin type blood coagulation analyzer of claim 1.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 86203106 CN86203106U (en) | 1986-07-08 | 1986-07-08 | Rolling ball blood coagulation time assaying instrument |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 86203106 CN86203106U (en) | 1986-07-08 | 1986-07-08 | Rolling ball blood coagulation time assaying instrument |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN86203106U true CN86203106U (en) | 1987-02-18 |
Family
ID=4806480
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 86203106 Ceased CN86203106U (en) | 1986-07-08 | 1986-07-08 | Rolling ball blood coagulation time assaying instrument |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN86203106U (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008089604A1 (en) * | 2007-01-17 | 2008-07-31 | Gang Li | A device for measuring liquid coagulation time |
| CN102640004A (en) * | 2009-12-04 | 2012-08-15 | 株式会社日立高新技术 | Blood coagulation analyzer |
| WO2022188189A1 (en) * | 2021-03-12 | 2022-09-15 | 重庆南方数控设备股份有限公司 | Magnetic bead based thrombelastogram detection device and method |
-
1986
- 1986-07-08 CN CN 86203106 patent/CN86203106U/en not_active Ceased
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008089604A1 (en) * | 2007-01-17 | 2008-07-31 | Gang Li | A device for measuring liquid coagulation time |
| CN102640004A (en) * | 2009-12-04 | 2012-08-15 | 株式会社日立高新技术 | Blood coagulation analyzer |
| WO2022188189A1 (en) * | 2021-03-12 | 2022-09-15 | 重庆南方数控设备股份有限公司 | Magnetic bead based thrombelastogram detection device and method |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C17 | Cessation of patent right | ||
| CE01 | Termination of patent right |
Termination date: 19870909 |
|
| CE01 | Termination of patent right |