CN2917551Y - Full-field optical coherence tomography device by achromatic phase shifting - Google Patents
Full-field optical coherence tomography device by achromatic phase shifting Download PDFInfo
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- CN2917551Y CN2917551Y CN 200620105656 CN200620105656U CN2917551Y CN 2917551 Y CN2917551 Y CN 2917551Y CN 200620105656 CN200620105656 CN 200620105656 CN 200620105656 U CN200620105656 U CN 200620105656U CN 2917551 Y CN2917551 Y CN 2917551Y
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Abstract
The utility model discloses a full-court Optical Coherence Tomography imaging device that applies a dispersionless phase shifter. The light emitted from light source is separated into two paths successively through a collimation lens, a broadband dispersion prism, a Polaroid sheet, a dispersionless phase shifter and a broadband polarizing dispersion prism: one path is sent to a reference lens through a microobjective, while the reference lens and the microobjective are arranged on the precision electric control shuttle; the other path is sent to the sample through another microobjective that is arranged on the piezoelectric ceramics drive. One side of the light that returned from the reference lens and sample through the reflection of broadband dispersion prism is connected with the CCD-array detector through the imaging lens. The dispersionless phase shifter is arranged between the reference lens and the broadband polarizing dispersion prism so as to attain the amount of phase that is 8 times than the angle of rotation of the Lambada/2 wave plate or the Polaroid sheet. The polarization and polarization analyzer of the light beam and the matching of optical intensity between the reference arm and the sample arm are all completed by a Polaroid sheet. The utility model has the advantages of less apparatuses, simple structure and short measuring time.
Description
Technical field
This utility model relates to a kind of instrument that is used for radiodiagnosis, relates in particular to a kind of whole-field optically coherent chromatographic imaging device that adopts no-dispersion phase shifter.
Background technology
Optical coherent chromatographic imaging (Optical Coherence Tomography is called for short OCT) is the chromatography imaging technique that developed recently gets up, and can realize the organizational structure and the physiological function of live body inside are carried out noncontact, not damaged, high-resolution imaging.The OCT technology is used widely in biomedical sector and clinical diagnosis, can be used for also will playing a significant role in material science and basic research on the early diagnosis of diseases such as ophthalmology, skin.
The image taking speed that improves OCT is the target that people pursue always.Whole audience OCT obtains the two-dimensional cross-section image based on concurrent technique, and with respect to the spot scan imaging mode, image taking speed significantly improves.The signal extraction of whole audience OCT can be based on carrier frequency and phase shift dual mode, but required drive circuit of carrier frequency and subsequent treatment relative complex all.Utilize the piezoelectric ceramic actuator mobile mirror can realize the multistep phase shift, but this phase-shift phase based on space displacement is relevant with wavelength, is typical coloured dispersion phase shifter, in wideband light source OCT system, uses and to reduce the signal extraction precision.
Employings such as Y.Watanabe have been set up the (Y.Watanabe of whole audience OCT system based on the no-dispersion phase shifter of rotating wave plate, Y.Hayasaka, M.Sato, and N.Tanno, " Full-field optical coherencetomography by achromatic phase shifting with a rotating polarizer ", Applied Optics, 44 (8), 1387-1392,2005).As shown in Figure 1, use wideband polarization Amici prism 4 (being called for short PBS) beam split, between PBS 4 and reference mirror 9, PBS 4 and sample 10, place λ/4 wave plates 5 and 6 respectively, change the polarisation of light direction, make the light that returns from reference mirror 9 and sample 10 arrive at area array CCD detector 14 by PBS 4.But because the design of λ/4 wave plates is at specific wavelength, even adopt zero-th order waveplates, its wave-length coverage that is suitable for is also very limited, and the costing an arm and a leg of zero-th order waveplates.Therefore, for broadband OCT system, λ/4 wave plates 5 and 6 just can not correctly change the polarization state of all spectral components, thereby can't guarantee efficiently to arrive at area array CCD detector 14 by PBS 4 from the light that reference mirror 9 and sample 10 return.And, by fast axle from the horizontal by λ/2 wave plates 11 of 15 °, fast axle from the horizontal by λ/4 wave plates 12 of 75 ° with the no-dispersion phase shifter that constitutes of rotatory polarization sheet 13, be placed on the front of area array CCD detector 14 in the feeler arm, the light beam single can only obtain 4 times of phase-shift phases to the polaroid anglec of rotation by this no-dispersion phase shifter.
Summary of the invention
The purpose of this utility model is in order to overcome disadvantages of background technology, a kind of whole-field optically coherent chromatographic imaging device that adopts no-dispersion phase shifter to be provided.Use wideband light source to obtain high longitudinal resolution, and solve the no chromatic dispersion phase shift problem of broadband light with no-dispersion phase shifter.Being used in combination of broadband Amici prism (be called for short BS) and wideband polarization Amici prism (abbreviation PBS) saved λ/4 wave plates between PBS and sample, PBS and reference mirror in the traditional OCT system.No-dispersion phase shifter is arranged between BS and the PBS, can obtains 8 times of phase-shift phases, can only obtain 4 times of phase-shift phases, Measuring Time is shortened to the anglec of rotation greater than existing no-dispersion phase shifter layout to λ/2 wave plates or the polaroid anglec of rotation.And, an inclined to one side and analyzing of light beam, the light intensity coupling of reference arm and sample arm is all finished by a polaroid.
The technical scheme that its technical problem that solves this utility model adopts is:
Comprise light source, collimating lens, broadband Amici prism, polaroid, no-dispersion phase shifter, wideband polarization Amici prism, a pair of identical microcobjective, accurate electronic control translation stage, piezoelectric ceramic actuator, reference mirror, imaging len dough-making powder battle array ccd detector; The light that light source sends is divided into two-way successively behind collimating lens, broadband Amici prism, polaroid, no-dispersion phase shifter and wideband polarization Amici prism: the one tunnel through microcobjective to reference mirror, microcobjective and reference mirror are contained on the accurate electronic control translation stage; To sample, another microcobjective is contained on the piezoelectric ceramic actuator through another microcobjective on another road.In the side of Amici prism reflection in broadband, connect the area array CCD detector through imaging len from reference mirror and sample back light.
Described no-dispersion phase shifter is made up of from the horizontal by λ/4 wave plates of 45 ° from the horizontal by 45 ° λ/4 wave plates, the rotatable λ of quick shaft direction/2 wave plates and fast axle fast axle, and the rotatable λ of quick shaft direction/2 wave plates connect automatically controlled turntable.
Described no-dispersion phase shifter is made up of from the horizontal by 75 ° λ/4 wave plates and the rotatable polaroid of light transmission shaft from the horizontal by λ/2 wave plates of 15 °, fast axle fast axle, and the rotatable polaroid of light transmission shaft connects automatically controlled turntable.
Described light source is white light source, super luminescence diode, light emitting diode or LASER Light Source.
Compare with background technology, the utlity model has following advantage:
1, this utility model has shortened Measuring Time: owing to set up unique system layout, make light pass through no-dispersion phase shifter twice, can obtain 8 times of phase-shift phases to λ/2 wave plates or the polaroid anglec of rotation.And traditional no-dispersion phase shifter layout, light can only once pass through, and obtains 4 times of phase-shift phases to the anglec of rotation.Under the same conditions, this utility model can make Measuring Time shorten dramatically, and this is significant concerning the OCT that pursues fast detecting;
2, the utlity model has very strong phase shift algorithm adaptability: system hardware is not being made under the situation of any change, only need in λ/2 wave plates or polaroid rotary course of no-dispersion phase shifter, in the moment of needs images acquired, make it to rotate required angle, just can obtain required phaseshift step size and phase-shift phase, thereby can use existing various phase shift algorithm, as three-step approach, four step rule, five-step approach etc.;
3, this utility model is by being used in combination of broadband Amici prism and wideband polarization Amici prism, and deducted λ/4 wave plates between PBS and sample, PBS and reference mirror in the traditional OCT system; Particularly importantly, under the wideband light source condition, the polarization direction of using single λ/4 wave plates to change all spectral components is infeasible;
4, the system structure set up of this utility model is reduced to the usage quantity of device minimum: the minimizing of in above-mentioned 3, mentioning 2 blocks of λ/4 wave plates, a polaroid that uses has played three effects simultaneously: the light that transmits from light source is implemented partially, the light that returns from reference mirror and sample is implemented analyzing, implement reference arm by rotation light transmission shaft direction and mate with the light intensity of gage beam.
Description of drawings
The whole audience OCT system schematic that the Y.Watanabe that Fig. 1 mentions for this utility model etc. adopt rotatory polarization sheet no-dispersion phase shifter to set up;
Fig. 2 uses no-dispersion phase shifter whole audience OCT system schematic for this utility model;
Fig. 3 is a kind of composition structural representation of no-dispersion phase shifter in this utility model;
Fig. 4 is that the another kind of no-dispersion phase shifter in this utility model is formed structural representation;
Fig. 5 uses the control system sketch map of no-dispersion phase shifter whole audience OCT for this utility model.
Among the figure: 1. super luminescence diode (superluminescent diode) light source, 2. collimating lens, 3. light transmission shaft is from the horizontal by 45 ° the polarizer, 4. wideband polarization Amici prism, 5,6. λ/4 wave plates of fast from the horizontal by 45 °, 7,8. a pair of identical microcobjective, 9. reference mirror, 10. sample, 11. fast axle is from the horizontal by λ/2 wave plates of 15 °, 12. fast axle is from the horizontal by λ/4 wave plates of 75 °, 13. the rotatable polaroid of light transmission shaft, 14. area array CCD detector, wherein 11,12,13 constitute a kind of no-dispersion phase shifter based on the rotatory polarization sheet, 15. light source, 16. collimating lens, 17. broadband Amici prisms, 18. polaroids, 19. no-dispersion phase shifter, 20. the wideband polarization Amici prism, 21,22. a pair of identical microcobjective, 23. accurate electronic control translation stages, 24. piezoelectric ceramic actuator, 25. reference mirror, 26. samples, 27. imaging lens, 28. area array CCD detector, 29. λ/4 wave plates of fast from the horizontal by 45 °, the rotatable λ of 30. quick shaft directions/2 wave plates, λ/4 wave plates of 31. fast from the horizontal by 45 °, 32. automatically controlled turntable, 33. λ/2 wave plates of fast from the horizontal by 15 °, λ/4 wave plates of 34. fast from the horizontal by 75 °, the rotatable polaroid of 35. light transmission shaft directions, 36. image acquisition and analog-to-digital conversion card, 37. computer, 38. multi-channel digital and analogue transition cards, 39. automatically controlled turntable drive circuits, 40. accurate electronic control translation stage drive circuit, 41. piezoelectric ceramic actuator drive circuits.
The specific embodiment
Below in conjunction with drawings and Examples this utility model is further described:
As shown in Figure 2, a kind of whole-field optically coherent chromatographic imaging system that adopts no-dispersion phase shifter described in the utility model comprises: light source 15, collimating lens 16, broadband Amici prism 17, polaroid 18, no-dispersion phase shifter 19, wideband polarization Amici prism 20, a pair of identical microcobjective 21 and 22, accurate electronic control translation stage 23, piezoelectric ceramic actuator 24, reference mirror 25, sample 26, imaging len 27 dough-making powder battle array ccd detectors 28.Wherein light source 15 can be white light source, super luminescence diode, Light-Emitting Diode or LASER Light Source.
Fig. 3 is a kind of composition structural representation of no-dispersion phase shifter 19 in this utility model, it is made up of from the horizontal by λ/4 wave plates 31 of 45 ° from the horizontal by 45 ° λ/4 wave plates 29, the rotatable λ of quick shaft direction/2 wave plates 30 and fast axle fast axle, and the rotatable λ of quick shaft direction/2 wave plates 30 connect automatically controlled turntable 32.
Fig. 4 is that the another kind of no-dispersion phase shifter 19 in this utility model is formed structural representation, it is made up of from the horizontal by 75 ° λ/4 wave plates 34 and the rotatable polaroid 35 of light transmission shaft from the horizontal by λ/2 wave plates 33 of 15 °, fast axle fast axle, and the rotatable polaroid 35 of light transmission shaft connects automatically controlled turntable 32.
As shown in Figure 2, after the light that light source 15 sends was collimated by collimating lens 16, by 17 beam split of broadband Amici prism, wherein the light of reflecting part will not use and make it the effusion system, only uses the light of transmission part.Transillumination is polarized sheet 18 and resolves into orthogonal P polarized light and S polarized light, enters no-dispersion phase shifter 19 then.Drive λ/2 wave plates 30 or polaroid 35 by automatically controlled turntable 32, no-dispersion phase shifter 19 just can be the anglec of rotation of 2 times of the Phase delays of P polarized light, and the anglec of rotation of 2 times of the Phase advances of S polarized light, thereby make P from no-dispersion phase shifter 19 outgoing, the phase difference variable between the S polarized light for 4 times the anglec of rotation.Then, P, S polarized light incide on the wideband polarization Amici prism 20, wherein: the P polarized light sees through wideband polarization Amici prism 20, is focused on the reference mirror 25 by microcobjective 21 then; The S polarized light is focused on the sample 26 by microcobjective 22 then by 20 reflections of wideband polarization Amici prism.The P polarized light that reflects through reference mirror 25 still sees through wideband polarization Amici prism 20, is still reflected by wideband polarization Amici prism 20 through the S polarized light that sample 26 reflects or scattering is returned, and incides respectively on the no-dispersion phase shifter 19.The same with aforesaid mechanism, no-dispersion phase shifter 19 still makes the P through it, the anglec of rotation that the phase difference variable between the S polarized light is 4 times.Thereby no-dispersion phase shifter 19 makes back and forth phase difference variable total between twice P through it, the S polarized light for 8 times the anglec of rotation, also is to have obtained 8 times to the phase-shift phase of the anglec of rotation between reference arm (P polarized light) and the sample arm (S polarized light).From P, the S polarized light of no-dispersion phase shifter 19 outgoing, behind polaroid 18, the polarization direction of P, S polarized light becomes unanimity and can interfere.The light that transmits from polaroid 18 is again by 17 beam split of broadband Amici prism, and wherein only our required light of reflecting part is focused on by imaging len 27 on the image planes of area array CCD detector 28.When the light path of reference arm and sample arm in the coherence length of laser, and the luminous point that returns from reference mirror 25 and sample 26 just can interfere when the image planes of area array CCD detector 28 overlap.Area array CCD detector 28 is connected on the computer 37 via image acquisition and analog-to-digital conversion card 36, just can demonstrates interference fringe picture.
Control system structure of the present utility model as shown in Figure 5, come the image acquisition of chain of command battle array ccd detector 28 by image acquisition and analog-to-digital conversion card 36, and the analog electrical signal of detector 28 output is converted to digital signal, input to computer 37 then and carry out signal processing and pictorial display etc.Computer 37 converts digital command to analog electrical signal by multi-channel digital and analogue transition card 38, and wherein the first via inputs to automatically controlled turntable drive circuit 39, removes to drive automatically controlled turntable 32.λ/2 wave plates 30 or the polaroid 35 that are driven no-dispersion phase shifter by automatically controlled turntable 32 rotate, and do not have the chromatic dispersion phase shift.
As shown in Figure 5, the second road analog electrical signal by 38 outputs of multi-channel digital and analogue transition card inputs to electronic control translation stage drive circuit 40, removes to drive electronic control translation stage 23.Move together by electronic control translation stage 23 drive microcobjectives 21 and reference mirror 25, carry out light path and regulate.By the Third Road analog electrical signal of multi-channel digital and analogue transition card 38 outputs, input to the drive circuit 41 of piezoelectric ceramic actuator, remove to drive piezoelectric ceramic actuator 24.Drive microcobjective 22 by piezoelectric ceramic actuator 24 and move, carry out the focal adjustment of sample.The drive circuit 41 of above image acquisition and analog-to-digital conversion card 36, multi-channel digital and analogue transition card 38, automatically controlled turntable drive circuit 39, electronic control translation stage drive circuit 40 and piezoelectric ceramic actuator all can be bought from the market.
The concrete condition of relevant sample focal adjustment please refer to people's such as Y.Watanabe paper " Full-fieldoptical coherence tomography by achromatic phase shifting with a rotating polarizer ", Y.Watanabe, Y.Hayasaka, M.Sato, and N.Tanno.Applied Optics, 44 (8), 1387-1392,2005.
With four step phase shift algorithm is example, four width of cloth interferogram I
1, I
2, I
3And I
4For being gathered during by 0 °, 90 °, 180 ° and 270 ° at phase-shift phase respectively, these phase-shift phases are introduced by λ/2 wave plates 30 or polaroid 35 in the rotation no-dispersion phase shifter.Images acquired when the anglec of rotation of λ/2 wave plates 30 or polaroid 35 is respectively 0 °, 11.25 °, 22.5 ° and 33.75 °, corresponding phase-shift phase is required 0 °, 90 °, 180 ° and 270 °.Owing to what all wavelengths was introduced is identical phase-shift phase, so following monochromatic light four step phase shift formula stand good:
I in the formula is sample perpendicular to the width of cloth organization chart in the section of incident illumination optical axis.Also can use phase shift algorithm such as three steps, five steps, Carr é.
Accurate electronic control translation stage 23 is moved, just can select another section of sample interior to carry out imaging.Must be noted that the mobile of accurate electronic control translation stage 23 must carry out with interior in the coherence length of laser scope, exceed this scope and just no longer include the interference generation.
Claims (4)
1, adopts the whole-field optically coherent chromatographic imaging device of no-dispersion phase shifter, it is characterized in that: comprise light source (15), collimating lens (16), broadband Amici prism (17), polaroid (18), no-dispersion phase shifter (19), wideband polarization Amici prism (20), a pair of identical microcobjective (21,22), accurate electronic control translation stage (23), piezoelectric ceramic actuator (24), reference mirror (25), imaging len (27) dough-making powder battle array ccd detector (28); The light that light source (15) sends is divided into two-way successively behind collimating lens (16), broadband Amici prism (17), polaroid (18), no-dispersion phase shifter (19) and wideband polarization Amici prism (20): the one tunnel through microcobjective (21) to reference mirror (25), microcobjective (21) and reference mirror (25) are contained on the accurate electronic control translation stage (23); To sample (26), another microcobjective (22) is contained on the piezoelectric ceramic actuator (24) through another microcobjective (22) on another road.In the side of broadband Amici prism (17) reflection, connect area array CCD detector (28) through imaging len (27) from reference mirror (25) and sample (26) back light.
2, the whole-field optically coherent chromatographic imaging device of employing no-dispersion phase shifter according to claim 1, it is characterized in that: described no-dispersion phase shifter (19) is made up of from the horizontal by λ/4 wave plates (31) of 45 ° from the horizontal by 45 ° λ/4 wave plates (29), the rotatable λ of quick shaft direction/2 wave plates (30) and fast axle fast axle, and the rotatable λ of quick shaft direction/2 wave plates (30) connect automatically controlled turntable (32).
3, the whole-field optically coherent chromatographic imaging device of employing no-dispersion phase shifter according to claim 1, it is characterized in that: described no-dispersion phase shifter (19) is made up of from the horizontal by 75 ° λ/4 wave plates (34) and the rotatable polaroid of light transmission shaft (35) from the horizontal by λ/2 wave plates (33) of 15 °, fast axle fast axle, and the rotatable polaroid of light transmission shaft (35) connects automatically controlled turntable (32).
4, the whole-field optically coherent chromatographic imaging device of employing no-dispersion phase shifter according to claim 1 is characterized in that: described light source (15) is white light source, super luminescence diode, light emitting diode or LASER Light Source.
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| CN 200620105656 CN2917551Y (en) | 2006-07-13 | 2006-07-13 | Full-field optical coherence tomography device by achromatic phase shifting |
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| CN 200620105656 CN2917551Y (en) | 2006-07-13 | 2006-07-13 | Full-field optical coherence tomography device by achromatic phase shifting |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100386053C (en) * | 2006-07-13 | 2008-05-07 | 浙江大学 | Whole-field optically coherent chromatographic imaging system with no-dispersion phase shifter |
| CN102706282A (en) * | 2012-06-25 | 2012-10-03 | 无锡迈福光学科技有限公司 | Laser interference range finder |
| CN103144036A (en) * | 2012-12-31 | 2013-06-12 | 南京理工大学 | Grinding amount on-line monitoring device at ring-polishing stage and grinding amount on-line monitoring method |
| CN111879708A (en) * | 2019-06-03 | 2020-11-03 | 江南大学 | Device and method for measuring laser damage three-dimensional structure |
-
2006
- 2006-07-13 CN CN 200620105656 patent/CN2917551Y/en not_active Expired - Lifetime
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100386053C (en) * | 2006-07-13 | 2008-05-07 | 浙江大学 | Whole-field optically coherent chromatographic imaging system with no-dispersion phase shifter |
| CN102706282A (en) * | 2012-06-25 | 2012-10-03 | 无锡迈福光学科技有限公司 | Laser interference range finder |
| CN102706282B (en) * | 2012-06-25 | 2014-08-20 | 无锡迈福光学科技有限公司 | Laser interference range finder |
| CN103144036A (en) * | 2012-12-31 | 2013-06-12 | 南京理工大学 | Grinding amount on-line monitoring device at ring-polishing stage and grinding amount on-line monitoring method |
| CN103144036B (en) * | 2012-12-31 | 2015-07-22 | 南京理工大学 | Grinding amount on-line monitoring device at ring-polishing stage and grinding amount on-line monitoring method |
| CN111879708A (en) * | 2019-06-03 | 2020-11-03 | 江南大学 | Device and method for measuring laser damage three-dimensional structure |
| CN111879708B (en) * | 2019-06-03 | 2021-07-27 | 江南大学 | Device and method for measuring laser damage three-dimensional structure |
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