CN2837836Y - Real-time fluorescence detection system for optical fiber receptor - Google Patents

Real-time fluorescence detection system for optical fiber receptor Download PDF

Info

Publication number
CN2837836Y
CN2837836Y CNU2005200468732U CN200520046873U CN2837836Y CN 2837836 Y CN2837836 Y CN 2837836Y CN U2005200468732 U CNU2005200468732 U CN U2005200468732U CN 200520046873 U CN200520046873 U CN 200520046873U CN 2837836 Y CN2837836 Y CN 2837836Y
Authority
CN
China
Prior art keywords
optical fiber
fiber receptor
real
signal
fluorescence detection
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CNU2005200468732U
Other languages
Chinese (zh)
Inventor
白春学
蒋进军
钟伟
宋元林
高磊
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zhongshan Hospital Fudan University
Original Assignee
Zhongshan Hospital Fudan University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zhongshan Hospital Fudan University filed Critical Zhongshan Hospital Fudan University
Priority to CNU2005200468732U priority Critical patent/CN2837836Y/en
Application granted granted Critical
Publication of CN2837836Y publication Critical patent/CN2837836Y/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Landscapes

  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)

Abstract

The utility model belongs to the field of medical apparatuses, which relates to a real-time fluorescence detection system for an optical fiber receptor. The utility model is an integral device combined by a fluorescence optical system and a signal processing system so as to provide a real-time fluorescence detection system for an optical fiber receptor, wherein the fluorescence optical system is composed of a light-emitting diode (LED) source, an exciting optical filter, a dichroic mirror, an object lens and an emitting optical filter. The signal processing system comprises a photoelectric converter, a simulation-digital converter and a computer. The utility model can be matched with various optical fiber receptors to detect the concentration of an object detected by the optical fiber receptor and the continuous change of the object detected by the optical fiber receptor. The utility model has simple, scientific and reasonable structure, the use is easy, the practicability and the serviceability are good, and a patient can be treated under the safe state.

Description

Optical fiber receptor real-time fluorescence detection system
Technical field
The utility model belongs to medical instruments field, relates to the optical fiber receptor with the real-time fluorescence detection system with relate to the integration technology of fluorescent optics system and signal processing system.
Background technology
The rescue of multiple critical illness clinically need be carried out continuous detecting for vim and vigour, electrolyte etc., so that instruct the rescue for these critical illnesses.Research and develop out multiple optical fiber receptor at present, can be in electrolytical concentration change such as body continuous detecting vim and vigour, sodium, potassium and chlorions, the instrument that does not still still have system complete is used these receptors.Therefore being necessary the instrument that using system is complete--the optical fiber receptor cooperates the optical fiber receptor to detect and write down vim and vigour, electrolytical dynamic change in real time at body with the real-time fluorescence detection system.In the prior art, when rescuing critical illness and needing electrolytical concentration change such as continuous detecting vim and vigour, sodium, potassium and chlorion, mainly carry out respectively by the two independent parts system, one is the fluorescent optics system: the light of launching specific wavelength by optical filter, import the optical fiber receptor, collect the fluorescence that the optical fiber receptor sends by optical system again; Two is signal processing system: the fluorescence lead-in light electric transducer with collecting, light signal is converted to electric signal, and being suitable digital signal with electrical signal conversion, import computer at last by analogue-to-digital converters, pass through software records.Reflect the concentration and the variation thereof of measured material by the digital signal of computer record, be used for the detection and the record of various optical fiber receptor fluorescence signals.In the use, measurement data often occurs and owe complete, operation inconvenience instructs that therapeutic scheme is untimely, defective such as put in place.
Have not yet to see the report of complete optical fiber receptor with real-time detecting system.
Summary of the invention
The purpose of this utility model provides a kind of optical fiber receptor real-time fluorescence detection system, and it can be used with various optical fiber receptors, with the concentration of the material that detected at the real-time detection fiber receptor of body and continue to change.
The utility model relates to the optical fiber receptor with the real-time fluorescence detection system with relate to the integration technology of fluorescent optics system and signal processing system, proposed a kind of simple and reasonable, the integrated apparatus that fluorescent optics system and signal processing system are integrated.
Of the present utility model being constructed as follows: its main fluorescent optics system and signal processing system two parts are formed, and wherein the fluorescent optics system comprises: light emitting diode is as light source 1, exciter filter 2, and dichronic mirror 3, object lens 4, emission optical filter 5 is formed.After light source sends light, through exciter filter filtration, dichronic mirror reflection, cause the optical fiber receptor through object lens focusing, the fluorescence that receptor sends sees through dichronic mirror through object lens, and process emission optical filter filters fluorescence again.Wherein signal processing system comprises: photoelectric commutator 6, analog signal line 7, analogue-to-digital converters 8, data signal line 9, computer 10.Fluorescence input photoelectric commutator after fluorescing system is handled is converted to electric signal by light signal, and after electric signal entered analogue-to-digital converters, its signal was converted to digital signal by analog in nature, imports computer again, passes through software records.Described exciter filter, dichronic mirror, object lens, the emission optical filter is to install in order between photoelectric commutator and the analogue-to-digital converters.
The advantage of the utility model device is: the processing by fluorescent optics system and signal processing system will, the exciting light of specific wavelength is provided for the optical fiber receptor, and with of the processing of its fluorescence signal that sends by optical system and signal system, finally with data recording in computer, the real-time change by data reflects material concentration and the variation thereof that the optical fiber receptor is detected.Any optical fiber receptor based on the fluorescence principle all can be used.The utility model is simple in structure, scientific and reasonable, and is easy to use, and practicality and applicability are all good.
Description of drawings
Fig. 1. be the utility model apparatus structure synoptic diagram.
Wherein: light source 1, exciter filter 2, dichronic mirror 3, object lens 4, emission optical filter 5, photoelectric commutator 6, analog signal line 7, analogue-to-digital converters 8, data signal line 9, computer 10.
Embodiment
Embodiment 1
Accompanying drawing is the utility model embodiment accompanying drawing.
The utility model will be further described according to above-mentioned accompanying drawing.The utility model is by light source 1, exciter filter 2, and dichronic mirror 3, object lens 4, emission optical filter 5, photoelectric commutator 6, analog signal line 7, analogue-to-digital converters 8, data signal line 9, computer 10 connects and composes.Wherein the light emitting diode in the fluorescent optics system is as light source, after light source sends light, through exciter filter filtration, dichronic mirror reflection, cause the optical fiber receptor through object lens focusing, the fluorescence that receptor sends sees through dichronic mirror through object lens, filters fluorescence through the emission optical filter again; Fluorescence input photoelectric commutator after fluorescing system is handled is converted to electric signal by light signal, and after electric signal entered analogue-to-digital converters, its signal was converted to digital signal by analog in nature, imports computer again, passes through software records.Wherein exciter filter and emission optical filter are selected according to the requirement of optical fiber receptor.The real-time change that can show receptor institute detection material concentration by computer in real time.
The utility model is by the processing of fluorescent optics system and signal processing system, the exciting light of specific wavelength can be provided for the optical fiber receptor, and with of the processing of its fluorescence signal that sends by optical system and signal system, finally with data recording in computer, the real-time change by data reflects material concentration and the variation thereof that the optical fiber receptor is detected.
The utility model can be treated the patient through clinic trial under the state of safety.

Claims (5)

1, optical fiber receptor real-time fluorescence detection system is characterized in that being made up of fluorescent optics system and signal processing system two parts, and wherein the fluorescent optics system comprises: light source 1, and exciter filter 2, dichronic mirror 3, object lens 4, emission optical filter 5 is formed; Wherein signal processing system comprises: photoelectric commutator 6, analog signal line 7, analog-digital converter 8, data signal line 9, computer 10.
2, optical fiber receptor real-time fluorescence detection system according to claim 1 is characterized in that described exciter filter, dichronic mirror, and object lens, the emission optical filter is to install in order between photoelectric commutator and the analog-digital converter.
3, optical fiber receptor real-time fluorescence detection system according to claim 1, it is characterized in that described fluorescent optics system with light emitting diode as light source, after light source sends light, through exciter filter filtration, dichronic mirror reflection, cause the optical fiber receptor through object lens focusing, the fluorescence that receptor sends sees through dichronic mirror through object lens, filters fluorescence through the emission optical filter again.
4, optical fiber receptor real-time fluorescence detection system according to claim 1, it is characterized in that described signal processing system is with above-mentioned filtration fluorescence input photoelectric commutator, be converted to electric signal by light signal, after electric signal enters analog-digital converter, its signal is converted to digital signal by analog in nature, import computer again, pass through software records.
5, according to claim 1 or 2 or 3 described optical fiber receptor real-time fluorescence detection systems, it is characterized in that described exciter filter and the emission optical filter select according to the requirement of optical fiber receptor.
CNU2005200468732U 2005-11-24 2005-11-24 Real-time fluorescence detection system for optical fiber receptor Expired - Lifetime CN2837836Y (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CNU2005200468732U CN2837836Y (en) 2005-11-24 2005-11-24 Real-time fluorescence detection system for optical fiber receptor

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CNU2005200468732U CN2837836Y (en) 2005-11-24 2005-11-24 Real-time fluorescence detection system for optical fiber receptor

Publications (1)

Publication Number Publication Date
CN2837836Y true CN2837836Y (en) 2006-11-15

Family

ID=37392323

Family Applications (1)

Application Number Title Priority Date Filing Date
CNU2005200468732U Expired - Lifetime CN2837836Y (en) 2005-11-24 2005-11-24 Real-time fluorescence detection system for optical fiber receptor

Country Status (1)

Country Link
CN (1) CN2837836Y (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013071822A1 (en) * 2011-11-15 2013-05-23 深圳大学 Chloride ion fluorescence detection method and device, and use thereof
CN103616359A (en) * 2013-12-04 2014-03-05 中国检验检疫科学研究院 Fluorescent quantitative detection method for green fluorescent protein (GFP)
CN104237179A (en) * 2013-06-14 2014-12-24 天津奇谱光电技术有限公司 Optical fiber sensing equipment by fluorescence method

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013071822A1 (en) * 2011-11-15 2013-05-23 深圳大学 Chloride ion fluorescence detection method and device, and use thereof
CN104237179A (en) * 2013-06-14 2014-12-24 天津奇谱光电技术有限公司 Optical fiber sensing equipment by fluorescence method
CN103616359A (en) * 2013-12-04 2014-03-05 中国检验检疫科学研究院 Fluorescent quantitative detection method for green fluorescent protein (GFP)

Similar Documents

Publication Publication Date Title
CN100526883C (en) Reflection photometer of gold-labeled immunity test paper strip
CA2517252A1 (en) Detection of interproximal caries aided by optical sensor examining the occlusal surface of teeth
CN1873450A (en) Biosensor of full fiber optic evanescent wave
CN2837836Y (en) Real-time fluorescence detection system for optical fiber receptor
CN102590156B (en) In-situ integrated multi-spectrum measurement system and detection method
CN204988999U (en) Wide spectrum optic fibre water quality monitoring system
CN101156770A (en) A sleeping respiration interference testing apparatus
CN103505221A (en) Lossless method for quantitatively detecting blood glucose by utilizing Raman spectrum
CN102147365A (en) Handheld bioluminescent detector and detection method
CN101285762A (en) Multi-parameter immunity-chromatography test strip quantitative determination instrument
CN201177598Y (en) Gas detection device
CN1672628A (en) Dynamic spectrometry instrument with multiple wavelength LED
CN1215814C (en) Tester for saturation level of cerebral blood oxygen
CN1727878A (en) A kind of detector of fluorescence induced by light-emitting diode in high brightness
CN202404012U (en) Optical system of spectrophotometer for biochemical analyzer
CN113376822B (en) Illumination system for a microscope, system, method and computer program for a microscope, and microscope system
CN110082334A (en) A kind of multichannel optical fiber fluorescent optical sensor
CN103033464A (en) Photoacoustic-fluorescence flow cytometer
CN1896723A (en) Array light-emitting diode induced fluorescent tester
CN105388131A (en) Fluorescence detection instrument and system based on micro-fluidic chip
CN102778434A (en) Turbidity transducer for online detection of water quality and detection method thereof
CN115524312A (en) Portable near-infrared SPR detection device
CN205430401U (en) High -speed image processing system
CN207937360U (en) A kind of miniature fiber sensor-based system based on evanescent wave
CN112240870B (en) System and method for measuring water content of crude oil

Legal Events

Date Code Title Description
C14 Grant of patent or utility model
GR01 Patent grant
CX01 Expiry of patent term

Granted publication date: 20061115

EXPY Termination of patent right or utility model