CN1215814C - Tester for saturation level of cerebral blood oxygen - Google Patents
Tester for saturation level of cerebral blood oxygen Download PDFInfo
- Publication number
- CN1215814C CN1215814C CN 02104867 CN02104867A CN1215814C CN 1215814 C CN1215814 C CN 1215814C CN 02104867 CN02104867 CN 02104867 CN 02104867 A CN02104867 A CN 02104867A CN 1215814 C CN1215814 C CN 1215814C
- Authority
- CN
- China
- Prior art keywords
- blood oxygen
- oxygen saturation
- cerebral blood
- amplifier
- brain
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Images
Landscapes
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
Abstract
The present invention relates to a detector for detecting the blood oxygen saturation of the brain, which belongs to the technical field of medical devices. At present, blood oxygen instruments clinically used at both home and abroad can only detect the oxygen saturation of blood oxygen saturation of finger tips or earlobes or is specifically used for monitoring the oxygen saturation of blood of pipelines of an extracardiac operation extracorporeal circulation system and can not detect the oxygen saturation of blood of the brain, and the detecting parts are limited. Therefore, light-emitting diodes which can emit two different wavelengths and two light-receiving elements (two silicon photocells) are arranged in a detecting probe of the present invention; one path of obtained detecting data is information having superficial layer tissues, and the other path is blood oxygen information having the superficial layer tissues and brain tissues; and the two paths are subtracted mutually, and thus, information which has only brain blood oxygen can be obtained. The detector is composed of a probe, a synchronous amplifier, an A/D converter, a single-chip computer system, a display, etc. The detector has the advantages of simple structure, convenient operation, high sensitivity, high reliability and low price. Besides, a software system is programmed by the C Language.
Description
Technical field
Title of the present invention is the cerebral blood oxygen saturation detector, is a kind of no wound, reflective, dual-beam and double reception formula detector, belongs to technical field of medical instruments.
Technical background
At present, the blood oxygen instrument that is used for both at home and abroad clinically almost all adopts a finger-clipped pick off that is made of light emitting diode and light-sensitive element, utilizes transmission-type to detect the blood oxygen saturation that principle detects finger tip or ear-lobe appearance blood.Change with pulse because of holding blood volume, so this instrument is called pulse blood oxygen instrument, it only is adapted at finger tip and the use of ear-lobe position, for the detection of brain blood oxygen, flesh blood oxygen and some local blood oxygen saturation with powerless; Other has the file of publication number CN2362122Y to disclose a kind of reflective blood oxygen saturation monitoring instrument, its pick off has used two light emitting diodes and a light sensitive diode, it is single receiving type structure, it is the blood oxygen saturation that is specifically designed to blood in the monitoring heart outer operation extracorporeal circulation system pipeline, also can't detect the blood oxygen saturation of cerebral tissue.In a word, above-mentioned these instruments all can not detect the blood oxygen saturation of cerebral tissue on external no wound ground.Topmost problem is not have the data that wound ground detects brain.
Summary of the invention
For the noinvasive that solves the blood oxygen of brain saturation detects problem, the invention provides a kind of instrument-cerebral blood oxygen saturation detector that wound ground detects cerebral blood oxygen saturation that do not have
The theory of institute of the present invention foundation is: lambert-Bi Er (Lambert-Beer) law.
The present invention is realized by following technical scheme:
The formation of cerebral blood oxygen saturation detector, it comprises: pick off 2, signal conditioner 3, synchronizing amplifier 4, A/D converter 5, Single Chip Microcomputer (SCM) system 6, liquid crystal display 7 and mini-printer 8 etc.Pick off 2 and signal conditioner 3 are loaded in the detection probe; Synchronizing amplifier 4, A/D converter 5, Single Chip Microcomputer (SCM) system 6, liquid crystal display 7 and mini-printer 8 are loaded in the mainframe box; Be connected with multicore cable therebetween.Be provided with the light emitting diode of two kinds of different wave lengths in the pick off, they can be according to the rules sequential successively conducting send the detection light beam, through the tissue scattering, arrive light cell 13,14 respectively, obtain the two-way voltage signal respectively through the I/V conversion, one tunnel information that has a shallow layer tissue wherein, another road not only has the blood oxygen information that shallow layer tissue's information also has cerebral tissue, this binary signal subtracts each other through differential amplifier, just can only be contained the voltage signal of brain blood oxygen information.
In the signal conditioner 3, two I/V changers guarantee silicon cell output short-circuit condition and the output current of silicon cell are converted to voltage output.Differential amplifier plays subtractor, and two transistor Ts 1, T2 constitute LED driving circuit.Synchronizing amplifier 4 is made of two in-phase amplifiers (being made of A4, A5 and related resistors respectively) and two analog switches (4066), and A/D converter 5, Single Chip Microcomputer (SCM) system 6, liquid crystal display 7 and mini-printer 8 all adopt prior art.
Software system of the present invention is worked out with the C language, and its major function is: synchronously gather two paths of data, and carry out digital filtering; Calculate dynamic cerebral blood oxygen saturation value and oscillography continuously and show it; Calculate the average of cerebral blood oxygen saturation continuously and show it; Produce clock signal, be used for successively two light emitting diodes of gating and separated in synchronization and two light emitting diodes corresponding signal that contains blood oxygen information during conducting separately.
The invention has the beneficial effects as follows: solved a difficult problem that detects cerebral blood oxygen saturation on external no wound ground; A kind of advanced person's diagnosis and treatment instrument is provided to medical profession; Owing to adopt dual collector and subtractor (differential amplifier), eliminated the influence of the scattered light of textura epidermoidea (scalp, skull etc.) to measurement result, also eliminated the interference of bias light simultaneously; Owing to adopt the synchronous acquisition data, so make the gained signal more accurate.Show because of oximetry value being carried out dynamic oscillography, so can react intracranial blood oxygen condition situation of change truly.Show through prototype experiment of the present invention: this apparatus structure is simple, easy to operate, sensitive reliable, cheap.
Description of drawings
Fig. 1: theory diagram of the present invention
Fig. 2: schematic block circuit diagram of the present invention
Fig. 3: the structural representation of detection probe of the present invention
Wherein:
1-tested person body region (forehead) 7-liquid crystal display
2-pick off 8-mini-printer
3-signal conditioner 11-red light emitting diodes
4-synchronizing amplifier 12-infrarede emitting diode
5-A/D transducer 13-silicon cell
6-Single Chip Microcomputer (SCM) system 14-silicon cell
The specific embodiment
The invention will be further described below in conjunction with accompanying drawing:
Among Fig. 1, pick off 2, signal conditioner 3, synchronizing amplifier 4, A/D converter 5, Single Chip Microcomputer (SCM) system 6 and liquid crystal display and/or mini-printer 8 be electrical ties successively.In addition, Single Chip Microcomputer (SCM) system 6 is sent clock signal signal conditioner and synchronizing amplifier is controlled.
Among Fig. 2, A1, A2, A3 are 3/4LF444, and A4, A5 adopt LF442, and transistor T 1, T2 adopt 8050 transistor npn npns, and silicon cell 13,14 adopts 5 * 5 silicon cells.
Fig. 3 is the structure chart of the detection probe of the embodiment of the invention, super bright light emitting diode 11 and infrarede emitting diode 12 are vertically near installation among the figure, it is shallow-layer (scalp, skull etc.) receptor that silicon cell 13,14,13 is housed on its contact point horizontal line, claims the auxiliary reception device; 14 is deep layer (scalp, skull, brain etc.) receptor, is called main receptor.
In the pick off 2, light source is made of super bright red light emitting diodes (wavelength 660nm) 11 and infrarede emitting diode (wavelength 940nm) 12, and conducting is luminous successively for the sequential that they can be according to the rules; Light-sensitive element uses two silicon cells 13,14, is fabulous linear relationship between its output short circuit current and the receiving light power, be photosensitive two, audion is incomparable; In the signal conditioner 3, the effect of two I/V changers (being made of A1, A2 and related resistors respectively) has two: one guarantees silicon cell output short-circuit condition, and its two output current with silicon cell is converted to voltage output; Differential amplifier (being made of A3 and 4 relevant resistance) plays subtractor here, and two transistor Ts 1, T2 constitute LED driving circuit; Synchronizing amplifier 4 is made of two in-phase amplifiers (being made of A4, A5 and related resistors respectively) and two analog switches (4066), controls its break-make by the time sequential pulse that single-chip microcomputer sends, with the purpose that realizes amplifying synchronously; And A/D converter 5, Single Chip Microcomputer (SCM) system 6, liquid crystal display 7 and mini-printer 8 all adopt prior art.
Testing process of the present invention is: pick off is installed on the human body forehead, the super bright red light emitting diodes 11 of gating at first, light arrives light cell 13,14 respectively, obtain the two-way voltage signal respectively through the I/V conversion, one tunnel information that has a shallow layer tissue wherein, another road not only has the blood oxygen information that shallow layer tissue's information also has cerebral tissue, and this binary signal subtracts each other through differential amplifier, just can only be contained the voltage signal of brain blood oxygen information.Amplify output signal S through synchronizing amplifier (constituting) again by A4 and related resistors
1, send Single Chip Microcomputer (SCM) system 6 storages and handle through A/D converter 5 collection-conversions.The gating infrarede emitting diode 12 again, and processing procedure is identical with said process, just through synchronizing amplifier (being made of A5 and related resistors) output signal S
2, and then the super bright red light emitting diodes 11 of gating repeats said process, continuous acquisition, storage and processing so again and again.When single-chip microcomputer is handled this two paths of signals, at first calculate S
1/ S
2Value, then according to relational expression rScO
2=f (S
1/ S
2) calculating, demonstration or print result.Result's display mode has two kinds: (1) dynamic tracking oscillography shows blood oxygen saturation (rScO
2); (2) show blood oxygen saturation (rScO
2) average.
Claims (3)
1. cerebral blood oxygen saturation detector, it comprises by detection probe, synchronizing amplifier, A/D converter, Single Chip Microcomputer (SCM) system, liquid crystal display and mini-printer, it is characterized in that:
Detection probe is made of pick off (2) and signal conditioner (3), in the pick off (2), light source is made of the super bright red light emitting diodes (11) of 660nm wavelength and the infrarede emitting diode (12) of 940nm wavelength, they can be according to the rules sequential successively conducting send the detection light beam, by tested tissue (1) scattering, by two silicon cells (13,14) light-sensitive element of Gou Chenging receives, output short circuit current is given in the signal conditioner (3) respectively by operational amplifier A 1, the I/V changer that A2 and related resistors constitute is transformed into voltage and exports to by operational amplifier A 3 and 4 relevant differential amplifiers that resistance constitutes; This differential amplifier plays subtractor here, and two transistor Ts 1, T2 constitute LED driving circuit, and signal conditioner (3) flows to synchronizing amplifier (4) with the voltage signal of blood oxygen information; Synchronizing amplifier (4) is made up of in-phase amplifier and two analog switch 2/4CD4066 that two operational amplifier A 4, A5 and related resistors constitute, and controls its break-make by the time sequential pulse that single-chip microcomputer sends, with the purpose that realizes amplifying;
The voltage signal of synchronizing amplifier (4) is exported to A/D converter (5), successively electrical ties Single Chip Microcomputer (SCM) system (6) and liquid crystal display and/or mini-printer (8).
2. according to the described cerebral blood oxygen saturation detector of claim 1, it is characterized in that: A1, A2, A3 are four high guaily unit 3/4LF444, A4, A5 adopt LF442, and transistor T 1, T2 adopt the C8050 transistor npn npn, and silicon cell (13,14) adopts 5 * 5 silicon cells.
3. according to the described cerebral blood oxygen saturation detector of claim 1, it is characterized in that: according to the described cerebral blood oxygen saturation detector of claim 1, it also comprises software system, and this software system is worked out with the C language, its major function is: synchronously gather two paths of data, and carry out digital filtering; Calculate dynamic cerebral blood oxygen saturation value continuously, and oscillography shows it; Calculate the average of cerebral blood oxygen saturation continuously, and show it; Produce clock signal, be used for successively two light emitting diodes of gating and separated in synchronization and two light emitting diodes corresponding signal that contains blood oxygen information during conducting separately.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 02104867 CN1215814C (en) | 2002-02-26 | 2002-02-26 | Tester for saturation level of cerebral blood oxygen |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 02104867 CN1215814C (en) | 2002-02-26 | 2002-02-26 | Tester for saturation level of cerebral blood oxygen |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1365649A CN1365649A (en) | 2002-08-28 |
| CN1215814C true CN1215814C (en) | 2005-08-24 |
Family
ID=4740136
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 02104867 Expired - Fee Related CN1215814C (en) | 2002-02-26 | 2002-02-26 | Tester for saturation level of cerebral blood oxygen |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1215814C (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100453041C (en) * | 2005-10-20 | 2009-01-21 | 暨南大学 | Anesthesia depth monitor utilizing auditory stimulation and near infrared spectroscopy |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005099564A1 (en) * | 2003-11-14 | 2005-10-27 | Tsinghua University | An apparatus of and method for measuring the parameter of the blood oxygen metabolism in human tissue |
| CN1317994C (en) * | 2004-05-21 | 2007-05-30 | 天津大学 | Time-domain light-deivisding differential wavelength spectro meter for detecting artery blood content and detection method thereof |
| CN1299636C (en) * | 2004-05-21 | 2007-02-14 | 天津大学 | Double-probe differential wavelength spectrometer for detecting tissue content and detection method |
| CN1319487C (en) * | 2004-05-21 | 2007-06-06 | 天津大学 | Airspace light-diving differential wavelength spectro meter for detecting artery blood content and detection method thereof |
| US8050730B2 (en) | 2005-12-23 | 2011-11-01 | Shenzhen Mindray Bio-Medical Electrics Co., Ltd. | Method and apparatus for eliminating interference in pulse oxygen measurement |
| CN100384373C (en) * | 2006-05-30 | 2008-04-30 | 合肥安恒光电有限公司 | Calibrated tester of oximeter |
| CN101480339B (en) * | 2009-01-09 | 2010-08-11 | 清华大学深圳研究生院 | Method and system for realizing measurements of various physiological parameters |
| CN103784150A (en) * | 2012-10-30 | 2014-05-14 | 东莞永胜医疗制品有限公司 | Blood oxygen saturation measuring method and instrument |
| WO2014124520A1 (en) * | 2013-02-13 | 2014-08-21 | Mespere Lifesciences Inc. | Method and device for measuring venous blood oxygenation |
| CN104382604B (en) * | 2014-12-02 | 2016-08-31 | 重庆名希医疗器械有限公司 | Noinvasive brain blood oxygen measurement method of parameters |
| CN105411606A (en) * | 2016-01-08 | 2016-03-23 | 赵晓玲 | Medical blood oxygen saturation measurement system |
| CN108577858B (en) * | 2018-04-08 | 2023-12-19 | 博联众科（武汉）科技有限公司 | Automatic judging method and system for tissue blood oxygen saturation monitoring part |
-
2002
- 2002-02-26 CN CN 02104867 patent/CN1215814C/en not_active Expired - Fee Related
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100453041C (en) * | 2005-10-20 | 2009-01-21 | 暨南大学 | Anesthesia depth monitor utilizing auditory stimulation and near infrared spectroscopy |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1365649A (en) | 2002-08-28 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN1215814C (en) | Tester for saturation level of cerebral blood oxygen | |
| CN107157492B (en) | Embedded human physiological information noninvasive detection system and data processing method | |
| CN105205984B (en) | A kind of logging for UHV transmission line | |
| CN104107051B (en) | Portable multiple brain region blood oxygen detection and real-time display system | |
| CN104224159B (en) | Device for detecting microcirculation blood flow on body surface of acupuncture point | |
| CN100544669C (en) | A kind of sleeping respiration interference testing apparatus | |
| JPH08512217A (en) | Electronic processor for pulse oximeter | |
| JPH06213806A (en) | Double-function reading head of reflectivity measuring instrument | |
| CN110338813A (en) | A kind of Noninvasive Blood Glucose Detection Methods based on spectrum analysis | |
| CN102579053A (en) | Reflective pulse blood oxygen detecting method based on diffusion theory | |
| CN103027691B (en) | Digital Physiological And Biochemical Parameters measuring device and measuring method | |
| CN106308814A (en) | Blood sugar non-invasive detection instrument based on near infrared spectrum analysis and realization method thereof | |
| CN101564290A (en) | Optical multi-parameter physiology monitoring instrument | |
| US20030135098A1 (en) | Erythema measuring device | |
| CN204394527U (en) | Cerebral blood oxygen saturation non-invasive monitoring instrument | |
| JPS62109547A (en) | Oxymetry method and apparatus | |
| CN204379284U (en) | Upper limb tremor recording equipment between a kind of sleep period | |
| CN208511033U (en) | A kind of double blood oxygen Congenital Heart Disease of Newborns detectors | |
| CN105054943A (en) | Oxyhemoglobin saturation detection terminal bringing convenience to monitoring | |
| CN100453041C (en) | Anesthesia depth monitor utilizing auditory stimulation and near infrared spectroscopy | |
| CN104434126A (en) | Recording device for upper limp tremor during sleeping | |
| CN106264555A (en) | blood sugar detector | |
| CN1120427A (en) | Woundless monitor for pulse rate blood oxygen saturation degree | |
| CN104644145A (en) | Continuous non-invasive blood pressure measuring system | |
| CN204246125U (en) | A kind of electro cardio signal workstation |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C06 | Publication | ||
| PB01 | Publication | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C19 | Lapse of patent right due to non-payment of the annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |