CN2454769Y - Multi-point temp. detection device for on-body detection of local metabolic-rate of biologic live tissue - Google Patents

Abstract

The utility model relates to a multi-point temperature detection device for on-body detecting the local metabolic rate of a biologic live tissue, which comprises a multi-point temperature probe, a datum collection device and a computer. The multi-point temperature probe is composed of a thin-wall pipe, a wafer which is welded at the top end of the thin-wall pipe, a temperature sensor which is inlaid vertically on the pipe wall of the thin-wall pipe and a temperature sensor which is inlaid on the wafer. The circle center point of the wafer is provided with one temperature sensor, the periphery of the wafer is provided with four temperature sensors which are arranged in cross shape, a leading wire of each temperature sensor extends from the thin-wall pipe and is connected with the datum collection device, and the datum collection device is connected with the computer. The utility model has the advantages of simple structure, low cost, convenient operation, high precision and high response speed.

Description

Get the multi-point temp sniffer of the local metabolic rate of biological vital tissue in body examination

The utility model relates to a kind of multi-point temp sniffer that is used for getting in body examination biological living (comprising human body) tissue local metabolic rate, particularly a kind of by obtaining tested position temperature at the accurately fixing temperature sensor of a plurality of relative positions of fine probe special arrangement the space and time information so obtain this part metabolic rate get the multi-point temp sniffer of the local metabolic rate of biological vital tissue in body examination.

Biosome is mainly for the work done form that realizes various life processes and carry out in its body: 1. outside visible mechanical work, exemplary such as contraction of muscle work done; 2. the mechanical work that internal's activity (as breathing, blood pumping, peristalsis of the digest tract etc.) is consumed; 3. promote the electric work of nerve conduction; 4. drive the synthetic of new cell, to replace old and feeble and dead cell etc.The final performance that the back is three kinds is all to dissipate to be heat energy.Therefore when biosome does not have external movement (life state of nature), all metabolism all shows as thermal effect, and metabolic rate just is meant in the in-house heat production rate of unit volume, its size is for organization factors, the clinical practice that medical diagnosis on disease and treatment etc. are a large amount of and zoologizeing, the physiology rule of human body is significant, in the growth of delineation animal individual, growth and old and feeble aspect have also become an important experiment basis, for example the calorimetry data show, in the animal individual growth course, the heat production rate (metabolic rate) of unit volume presents certain rule.The physiologist has defined a basal metabolic rate for this reason, and it refers to that " the metabolic heat production amount that quiescent condition is the animal individual unit volume unit interval under the base state " (unit is: J/m ³S or W/m ³), this parameter size is an important physical index, plays an important role in animal comprises the heat analysis of human body.The variation of Fundamentals of Measurement metabolic rate has important meaning to the diagnosis of some disease.For example, the thyroid function deficiency, basal metabolic rate will be hanged down 20-40% than arm's length standard, and hyperthyroidism, basal metabolic rate is then than the high 25-80% of arm's length standard.In addition, we know, body generation pathology or when inflammation occurring can cause tissue metabolism's process to strengthen.Tumor locus also often exists unusual heat to produce rapidly owing to the glucolytic hyperfunction and rich blood vessel of immature cell and growth.One of major function of metabolic heat production also is to make animal to keep a highly stable temperature.In a word, for above-mentioned reasons, be the target that people competitively explore with regard to the research of metabolic rate measuring method and instrument always.

Because each tissue is different with the activity of organ, organize whole body metabolic rate size everywhere in fact to differ greatly, they have reflected different physiology problems, if can go out the metabolic rate size at these positions in body examination at different tissues and organ, then have the important medical physiologic meaning.

Yet the present situation that measures the animal metabolism rate at present is: after normally animal being placed an enclosure space, again according to the volume flow rate of blood in measured expiration and the breathing process and wherein the variation of oxygen concentration calculate the animal metabolism rate.The animal metabolism rate that this method measures is the total metabolism rate of animal individual.Obviously, this involves a series of biochemical analysis steps, and implements very loaded down with trivial details, the more important thing is that the total metabolism rate of acquisition can not be represented the metabolism status of local organization.At present, the metabolic rate of measuring local organization is also unsuccessful, generally all is that the small sample that exsomatizes is directly measured calorific value or infers metabolic rate from the local measured value of oxygen consumption.And this can not represent real tissue metabolism state, and it is very loaded down with trivial details, difficult to operate, and precision is difficult to guarantee, most importantly, is difficult to reflect local metabolism status.So, still incompetent so far device appearance of getting the local organization metabolic rate in body examination.

The utility model purpose is to provide a kind of and gets biological vital tissue (comprising human body) local organization metabolic rate Q in body examination ^* _mThe multi-point temp sniffer, this apparatus structure is simple, with low cost, be microtrauma type, damaging little, easy to operate, only the accurately fixing temperature sensor of a plurality of relative positions by special setting on a fine probe (as thermopair etc.) obtains the space and the time information of tested position temperature, and then obtain the comprehensive metabolic rate in this position, and precision height, response speed is fast, temperature-measuring range is wide, fills up to get in the biological vital tissue local organization metabolic rate field in body examination and does not have the blank that measures device.

Embodiment of the present utility model is as follows:

What the utility model provided gets the multi-point temp sniffer of the local metabolic rate of biological vital tissue in body examination, it is characterized in that, comprise the multi-point temp probe A, data collecting instrument B and computing machine C, wherein, the multi-point temp probe A is by thin walled tube 8, be welded in the disk 9 on thin walled tube 8 tops, being parallel to thin walled tube 8 axis vertically welds the 3-5 piece of temperature sensor that is embedded on thin walled tube 8 tube walls and welds 5 pieces of temperature sensors that are embedded on the disk 9, temperature sensor 5 in 5 pieces of temperature sensors is positioned at the circle centre position of disk 9, all the other 4 pieces of temperature sensors 1,2,3 and 4 are the cruciform arrangement lays respectively on the periphery of disk 9, each temperature sensor wires is packed in the pipe of thin walled tube 8, draw the input end that is connected in data collecting instrument B from thin walled tube 8 bottoms, the output terminal of data collecting instrument B connects computing machine, computing machine external power supply;

Thin walled tube 8 diameters of multi-point temp probe A are 1-2mm, and length is 20-100mm;

The material of the disk 9 on described thin walled tube 8 and its top is the stainless steel or the glass of low heat conductivity;

Described temperature sensor is thermocouple temperature sensor or resistance temperature sensor, and the distance between the temperature sensor is 0.1-1mm.

What the utility model provided gets the multi-point temp sniffer of the local metabolic rate of biological vital tissue in body examination, its advantage is: simple in structure, with low cost, easy to operate, only by can obtain the space and the time information of tested position temperature easily at the accurately fixing temperature sensor of a plurality of relative positions of special setting on fine probe (as thermopair etc.), and then obtain this position metabolic rate, and precision height, response speed is fast, temperature-measuring range is wide, fills up to get in the biological vital tissue local organization metabolic rate field in body examination and does not have the blank that measures device.

Its principle of work is:

The heat balance relational expression that has general applicability in the tissue is: $\mathrm{\ρc}\frac{\∂T}{\∂t}=\▿\·(k\▿T)+{\mathrm{\ω}}_b{\mathrm{\ρ}}_b{c}_b(T_a-T)+Q_m(x,y,z,t)---\left(1\right)$ ρ wherein, c is respectively density, the specific heat of tissue; K is for organizing thermal conductivity, ρ _b, c _bBe respectively the density and the specific heat of blood; ω _bBe blood perfusion rate; T _a, T is respectively arterial blood temperature and tissue temperature; Following formula can further be expressed as: $\mathrm{\ρc}\frac{\∂T}{\∂t}=\frac{\∂}{\∂x}\left(k_x\frac{\∂T}{\∂x}\right)+\frac{\∂}{\∂y}\left(k_y\frac{\∂T}{\∂y}\right)+\frac{\∂}{\∂z}\left(k_z\frac{\∂T}{\∂z}\right)+Q_m^{*}(x,y,z,t)---\left(2\right)$ Wherein, Q ^* _m(x, y, z, t)=ω _bρ _bc _b[T _a-T (x, y, z, t)]+Q _m(z t) is the comprehensive metabolic rate of local organization to be measured for x, y, and the metabolic rate of following indication all refers to this value.

Generally speaking, the density of tissue is relative with specific heat more stable, thereby need not measure, and its general value is: ρ=1000kg/m ³, c=4200J/kg ℃, and organize thermal conductivity generally to get constant k=0.5W/m ℃, so local metabolic rate is only relevant with the temperature field (comprising its transient changing rate) of detected part, so as long as record these information, then metabolic rate can be determined by following formula;

Can set up practical local metabolic rate measuring method in view of the above, its basic thought is: the multi-point temp probe that will comprise spatial information inserts in the tissue, and collects the temperature data of each measuring point, then can obtain local comprehensive metabolic rate by formula (2) to be: $Q_m^{*}(x,y,z,t)=\mathrm{\ρc}\frac{\∂T}{\∂t}-k\frac{{\∂}^{2}T}{{\∂x}^2}-k\frac{{\∂}^{2}T}{{\∂y}^2}-k\frac{{\∂}^{2}T}{{\∂z}^2}---\left(3\right)$ General since measured be basal metabolic rate, promptly under the animal rest state, in fact the metabolic rate measure equation can be reduced to: $Q_m^{*}(x,y,z)=-k\frac{{\∂}^{2}T}{{\∂x}^2}-k\frac{{\∂}^{2}T}{{\∂y}^2}-k\frac{{\∂}^{2}T}{{\∂z}^2}---\left(4\right)$ In the above-mentioned measurement, because the caused spread effect of insertion of probe, tissue temperature needs certain hour just can reach stable state.In this method, can after inserting probe, be the temperature signal of each measuring point of opening entry, the temperature information reflection of transient state be animal when inserted by probe institute cause and reflect and cause the change situation of metabolic rate.Nature, along with the continuity of time, measured metabolic rate numerical value should be tending towards a stationary value.So the metabolic rate that no matter measures is steady-state value or instantaneous value, it all sums up in the point that realization $\frac{\∂T}{\∂t},\frac{{\∂}^{2}T}{{\∂x}^2},\frac{{\∂}^{2}T}{{\∂y}^2}$ And $\frac{{\∂}^{2}T}{{\∂z}^2}$ Mensuration come up.Key of the present utility model just is that also designing corresponding temperature probe accomplishes this point.

What Fig. 1 provided is the multi-point temp probe A synoptic diagram that is provided with 7 pieces of temperature sensors (as thermopair), wherein the relative space position between each piece probe is strict fixing, so that measure at x, y, Temperature Distribution on three directions of z, and the distance between the probe (Δ x, Δ y, Δ z) the smaller the better under the prerequisite that guarantees to process (being generally 0.1-1mm), thus utilize measured temperature quite accurately to obtain in the formula (2) by method of difference $k\frac{{\&PartialD;}^{2}T}{{\&PartialD;x}^2},k\frac{{\&PartialD;}^{2}T}{{\&PartialD;y}^2}$ And $k\frac{{\&PartialD;}^{2}T}{{\&PartialD;z}^2}$ , and extrapolate the comprehensive metabolic rate numerical value of detected part thus.Following 5 the metabolic rate measuring methods of locating of stable state are discussed earlier.The concrete practice is, utilize data collecting instrument to record the temperature level of seven pieces of probes of end of probe after, then corresponding writing out located in 5 in the center of circle of multi-point temp probe A top disk $k\frac{{\&PartialD;}^{2}T}{{\&PartialD;x}^2}{|}_{\mathrm{point}5}\&ap;\mathrm{<figure-callout\; id="1"\; label="k\; T"\; filenames="Y0026477300122.png"\; state="\{\{state\}\}">k</figure-callout>}\frac{T_{}}{}\frac{{}_{1+}{T}_3-2T_5}{{\mathrm{\&Delta;x}}^2}$ ， $k\frac{{\&PartialD;}^{2}T}{{\&PartialD;y}^2}{|}_{\mathrm{point}5}\&ap;k\frac{T_2+T_4-2T_5}{{\mathrm{\&Delta;y}}^2},$ But locate for 5 $k\frac{{\&PartialD;}^{2}T}{{\&PartialD;z}^2}$ Measurement different with the former, because this probe structure is difficult to measure 5 values at two positions up and down in the z direction, be difficult to be provided with temperature sensor such as top, and there is location difficulty in the practice that moves up and down probe, and be difficult to measure the transient state metabolic rate, and 5 be probe interior with next, thereby measured temperature value is not tissue temperature, but the temperature value of probe interior.For overcoming this difficulty, we adopt locate at 6 $k\frac{{\&PartialD;}^{2}T}{{\&PartialD;z}^2}$ Value is dug approximate 5 locate corresponding that replace $k\frac{{\&PartialD;}^{2}T}{{\&PartialD;z}^2}$ Value, this is because the spacing between each piece thermopair is minimum in this probe structure, thereby 6 with 5 locate corresponding $k\frac{{\&PartialD;}^{2}T}{{\&PartialD;z}^2}$ Value is very approaching, and this has just solved a quite thorny technical barrier.And 6,7 temperature data records by the thermopair at this some place, so just has: $k\frac{{\&PartialD;}^{2}T}{{\&PartialD;z}^2}{|}_{\mathrm{point}5}\&ap;k\frac{{\&PartialD;}^{2}T}{{\&PartialD;z}^2}{|}_{\mathrm{<figure-callout\; id="6"\; label="point"\; filenames="Y0026477300122.png"\; state="\{\{state\}\}">point</figure-callout>}6}\&ap;k\frac{{\mathrm{<figure-callout\; id="1"\; label="T"\; filenames="Y0026477300122.png"\; state="\{\{state\}\}">T</figure-callout>}}_1+T_7-2{\mathrm{<figure-callout\; id="6"\; label="T"\; filenames="Y0026477300122.png"\; state="\{\{state\}\}">T</figure-callout>}}_6}{{\mathrm{\&Delta;z}}^2}.$ 。So the metabolic rate numerical value that can be got under the stable state by formula (4) is: $Q_m^{*}{|}_{\mathrm{point}5}\&ap;-\mathrm{<figure-callout\; id="1"\; label="k\; T"\; filenames="Y0026477300122.png"\; state="\{\{state\}\}">k</figure-callout>}\frac{T_{}}{}\frac{{}_1+T_3-2T_5}{{\mathrm{\&Delta;x}}^2}-k\frac{T_2+T_4-2T_5}{{\mathrm{\&Delta;y}}^2}-\mathrm{<figure-callout\; id="1"\; label="k\; T"\; filenames="Y0026477300122.png"\; state="\{\{state\}\}">k</figure-callout>}\frac{T_{}}{}\frac{{}_1+T_7-2{\mathrm{<figure-callout\; id="6"\; label="T"\; filenames="Y0026477300122.png"\; state="\{\{state\}\}">T</figure-callout>}}_6}{{\mathrm{\&Delta;z}}^2}---\left(5\right)$ If when Δ x=Δ y=Δ z=Δ s was set, following formula can be reduced to: $Q_m^{*}{|}_{\mathrm{point}5}\&ap;-k\frac{{2\mathrm{<figure-callout\; id="1"\; label="T"\; filenames="Y0026477300122.png"\; state="\{\{state\}\}">T</figure-callout>}}_1+T_2{+T}_3+T_4+T_7-2T_6-4T_5}{{\mathrm{\&Delta;S}}^2}---\left(6\right)$ As seen, the multi-point temp probe that utilizes the utility model to provide, after the temperature level of obtaining 7 point of fixity, the tissue metabolism that can measure end of probe center (promptly locating) at 5 leads.

For 5 transient microstructure metabolic rates of locating, the utility model is still quite effective.Here measuring principle is done an explanation.At this moment, with above-mentioned stable situation slightly difference be need to obtain the transient temperature value at every bit place, so, similarly, establish k and be stable state constantly, and carve at this moment and measure the each point temperature T ^k ₁, T ^k ₂..., T ^k ₇, then recording k+1 temperature value T constantly ^K+1 ₁, T ^K+1 ₂..., T ^K+1 ₇After, locate should have mutually at 5, $k\frac{{\&PartialD;}^{2}T}{{\&PartialD;x}^2}{|}_{\mathrm{point}5}^{k+1}\&ap;k\frac{T_1^{k+1}+T_3^{k+1}-2T_5^{k+1}}{{\mathrm{\&Delta;x}}^2},k\frac{{\&PartialD;}^{2}T}{{\&PartialD;y}^2}{|}_{\mathrm{point}5}^{k+1}\&ap;k\frac{T_2^{k+1}+T_4^{k+1}-2T_5^{k+1}}{{\mathrm{\&Delta;y}}^2},$ $k\frac{{\&PartialD;}^{2}T}{{\&PartialD;z}^2}{|}_{\mathrm{point}5}^{k+1}\&ap;k\frac{{\&PartialD;}^{2}T}{{\&PartialD;z}^2}{|}_{\mathrm{point}6}^{k+1}\&ap;k\frac{T_1^{k+1}+T_7^{k+1}-2T_6^{k+1}}{{\mathrm{\&Delta;z}}^2}---\left(7\right)$ And the transient volume in the equation (3) is: $\mathrm{\&rho;c}\frac{\&PartialD;T}{\&PartialD;t}{|}_{\mathrm{point}5}^{k+1}\&ap;\mathrm{\&rho;c}\frac{T_5^{k+1}-T_5^k}{\mathrm{\&Delta;t}}---\left(8\right)$ Here, the time interval, Δ t should be as far as possible little, to reduce the error that difference is brought.Thus, can obtain k+1 tissue metabolism constantly lead into: $Q_m^{*}{|}_{\mathrm{point}5}^{k+1}\&ap;\mathrm{\&rho;c}\frac{T_5^{k+1}-T_5^k}{\mathrm{\&Delta;t}}-k\frac{T_1^{k+1}+T_3^{k+1}-2T_5^{k+1}}{{\mathrm{\&Delta;x}}^2}-k\frac{T_2^{k+1}+T_4^{k+1}-2T_5^{k+1}}{{\mathrm{\&Delta;y}}^2}-k\frac{T_1^{k+1}+T_7^{k+1}-2T_6^{k+1}}{{\mathrm{\&Delta;z}}^2}$ (9) same, when getting Δ x=Δ y=Δ z=Δ s, following formula can be reduced to: $Q_m^{*}\&ap;\mathrm{\&rho;c}\frac{T_5^{k+1}-T_5^k}{\mathrm{\&Delta;t}}-k\frac{2T_1^{k+1}+T_2^{k+1}+T_3^{k+1}+T_4^{k+1}+T_7^{k+1}-2T_6^{k+1}-4T_5^{k+1}}{{\mathrm{\&Delta;s}}^2}---\left(10\right)$

Thus, according to the transient temperature that each point collects, the tissue metabolism that can obtain changing leads.Whole process is write down automatically and calculates automatically in conjunction with computing machine by data collecting instrument.The user can read measured metabolic rate by display screen.

The utility model is described in further detail below in conjunction with the drawings and specific embodiments.

Fig. 1 is a structured flowchart of the present utility model;

Fig. 2 is the structural representation of multi-point temp probe A of the present utility model;

Fig. 3 is the vertical position view that is embedded in the temperature sensor on thin walled tube 8 tube walls;

Wherein: multi-point temp probe A data collecting instrument B computing machine C

Thin walled tube 8 disks 9, temperature sensor wires 10

Temperature sensor 1,2,3,4,5,6,7

As seen from the figure, what the utility model provided gets the multi-point temp sniffer of the local metabolic rate of biological vital tissue in body examination, it is characterized in that, comprise the multi-point temp probe A, data collecting instrument B and computing machine C, wherein, the multi-point temp probe A is by thin walled tube 8, be welded in the disk 9 on thin walled tube 8 tops, being parallel to thin walled tube 8 axis vertically welds the 3-5 piece of temperature sensor that is embedded on thin walled tube 8 tube walls and welds 5 pieces of temperature sensors compositions that are embedded on the disk 9, temperature sensor 5 in 5 pieces of temperature sensors is positioned at the circle centre position of disk 9, all the other 4 pieces of temperature sensors 1,2,3 and 4 are the cruciform arrangement lays respectively on the periphery of disk 9, each temperature sensor wires is packed in the pipe of thin walled tube 8, draw the input end that is connected in data collecting instrument B from thin walled tube 8 bottoms, the output terminal of data collecting instrument B connects computing machine, computing machine external power supply;

Thin wall tubule 8 diameters of multi-point temp probe A are 1-2mm, and length is 20-100mm;

The material of the disk 9 on described thin walled tube 8 and its top is the stainless steel or the glass of low heat conductivity; Described temperature sensor is thermocouple temperature sensor or resistance temperature sensor, and distance is 0.1-1mm between the temperature sensor.

According to the degree of depth of detected part, its probe length can design (but being generally 2-10cm) arbitrarily, is guaranteeing under the situation of assembly precision, and probe diameter should the smaller the better (being generally 1-2mm), and wound degree reduces to minimum in the tissue so that be inserted into; The exact position of thermopair spacing should be demarcated and be transported on the interior process software of computing machine, so that accurately calculate metabolic rate; The thermopair size also is advisable with minimum dimension under the prerequisite that can guarantee processing, the current commercial less thermocouple wire diameter that buys is 20 μ m, 80 μ m equidimensions, can directly use, or the littler thermopair of special as required processing, also can be with thermopair and the integrated manufacturing of probe tube.Thin walled tube 8 and disk 9 can adopt the stainless-steel tube of low heat conductivity to make; Also can adopt the glass casting to form;

Temperature sensor can be thermocouple temperature sensor; Also can adopt RTD; Temperature sensor (1 of the present utility model; 2; ...; 7) inlay (or welding) on the tube wall and top disk 9 of light-wall pipe 8; The thermal conductivity factor of light-wall pipe 8 materials should be as far as possible little; Cause bigger thermometric error to avoid heat conduction in it; Otherwise; Temperature sensor records will be the temperature of light-wall pipe 8 but not the temperature of the biological tissue that touches; 3 pieces of temperature sensors (1 on light-wall pipe 8 walls; 6; 7) vertically being a line along light-wall pipe 8 walls arranges; And 5 pieces of thermocouples on its top disk 9 (1; 2; 3; 4; 5) then across is arranged, wherein 4 piece (1,2; 3; 4) be arranged on the periphery of top disk 9, and the 5th piece be arranged in disk 9 centers, thus; The multi-point temp probe A that present embodiment provides has 7 pieces of multi-point temp probes (certainly; Can be as required 8 pieces or 9 pieces of multi-point temp probes, is 5 pieces such as the temperature sensor that vertically is a line layout along light-wall pipe 8 walls), the relative position between each temperature sensor is accurately fixing; Its coordinate information is stored in the data collecting instrument; So after obtaining the tissue temperature of these positions, according to temperature level and the position of each measuring point, can lead and extrapolate by will the pop one's head in tissue metabolism of top disk 9 centers of data collecting instrument and computer. Transient state or space metabolic rate heterogeneous can be presented on the computer screen, and provides different metabolic rate values constantly as requested.Data collecting instrument specifically can be selected the ratio of performance to price Agilent34907A type signals collecting and processor preferably for use.Move this probe, can measure the metabolic rate of different parts.So this is a kind of device of measuring local metabolic rate.The used computing machine of native system adopts plain edition to get final product, and price is very cheap, and performance meets the demands fully.Insert tissue (because of probe head is a plane) for ease of its probe, can have the syringe needle of sharp-pointed head in the front end outfit of probe, so that on skin, leave aperture, thus the insertion of subsidiary book probe.

Multi-point temp probe A number of assembling steps of the present utility model is as follows:

1. earlier on the tube wall of thin walled tube 8, leave micropore by calibration position, form evenly distributed serial aperture, its diameter is about about 80-100 μ m, at these micropore places with temperature sensor (6,7) node is welded on the wall, and expose, so that contact with biological tissue and measure this position temperature, the wire harness 10 of temperature sensor is then drawn in the pipe of its hollow;

2. after treating that thermopair (6,7) on the tube wall face installs, on disk 9, leave 5 apertures again, equally, weld totally 5 pieces of temperature sensors (1,2 at these aperture places, 3,4,5), afterwards, with these five pieces of temperature sensors (1,2,3,4,5) lead-in wire 10 is drawn by the lower end along pipe successively carefully, and wherein each piece temperature sensor will be marked;

3. the disk 9 that will be welded with 5 pieces of temperature sensors accurately closes the upper end of covering thin walled tube 5, and the two welding is fixing, so promptly makes the multi-point temp probe A that sensing station is determined.The temperature sensor output terminal is connected to the input end of data collecting instrument, and the cold disconnected compensation of temperature sensor is then inserted in the frozen water to obtain reference temperature.And data collecting instrument connects computing machine.Like this, the temperature signal that is collected at the multi-point temp sensor of multi-point temp probe A just is transported in the computing machine, thereby obtains the transient state metabolic rate numerical value that institute's location is put.

From the above mentioned, the utility model temperature sensor is a thermocouple temperature sensor (1,2, ..., 7) or resistance temperature sensor, its response speed is very fast, and it is cheap that precision height, price then are tending towards, and the multi-point temp probe A is made relatively easy, data acquisition and handle very convenient, no complicated circuit, simple in structure, the hot state ratio of thermometric and evaluation of tissue is easier to, test specification is wide, is applicable to that different deep biological tissue, different biological tissue's metabolic rate constantly measure.

When utilizing device of the present utility model to carry out measuring of the local metabolic rate of vivo biological tissue, can divide static state and dynamic two class situations to carry out.Here introduce the static measurement step earlier: the temperature sensor wires on the probe is connected to data acquisition instrument, and data acquisition instrument is plugged on the computing machine, then, probe is inserted tissue site to be tested, turn-on data Acquisition Instrument and computing machine then, so temperature sensor begins to gather the temperature signal at the position of touching, the simultaneous temperature signal is by data collecting instrument and computer monitoring, after treating that temperature signal that each piece temperature sensor is write down tends towards stability, stop to gather, can obtain the metabolic rate of stable state by formula (6), and organize the metabolic rate at other positions probe can be inserted the relevant position by obtaining with quadrat method.For the unstable state metabolic rate that causes by other factors such as external world's heating, cooling and other stimulations, only need the different temperature signals constantly of continuous monitoring, can calculate the transient state metabolic rate size of probe tip center tissue by formula (10).

Claims (5)

1. multi-point temp sniffer of getting the local metabolic rate of biological vital tissue in body examination, it is characterized in that, comprise the multi-point temp probe A, data collecting instrument B and computing machine C, the multi-point temp probe A is by thin walled tube (8), be welded in the disk (9) on thin walled tube (8) top, be parallel to thin walled tube (8) axis vertically welding be embedded in 5 pieces of temperature sensors that 3-5 piece of temperature sensor on thin walled tube (8) tube wall and welding be embedded on the disk (9) and form, temperature sensor (5) in 5 pieces of temperature sensors is positioned at the circle centre position of disk (9), all the other 4 pieces of temperature sensors (1), (2), (3) and (4) be cruciform and arrange and to lay respectively on the periphery of disk (9), each temperature sensor wires is packed in the pipe of thin walled tube (8), draw the input end that is connected in data collecting instrument B from thin walled tube (8) bottom, the output terminal of data collecting instrument B connects computing machine, computing machine external power supply.

2. get the multi-point temp sniffer of the local metabolic rate of biological vital tissue by claim 1 is described in body examination, it is characterized in that: the thin wall tubule of multi-point temp probe A (8) diameter is 1-2mm, and length is 20-100mm.

3. get the multi-point temp sniffer of the local metabolic rate of biological vital tissue by claim 1 is described in body examination, it is characterized in that: the material of the disk (5) on described thin walled tube (8) and its top is the stainless steel or the glass of low heat conductivity.

4. get the multi-point temp sniffer of the local metabolic rate of biological vital tissue by claim 1 is described in body examination, it is characterized in that: described temperature sensor is thermocouple temperature sensor or resistance temperature sensor.

5. get the multi-point temp sniffer of the local metabolic rate of biological vital tissue by claim 1 is described in body examination, it is characterized in that: the distance between the temperature sensor is 0.1-1mm.

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