CN2449219Y

CN2449219Y - Tissue chip preparing apparatus

Info

Publication number: CN2449219Y
Application number: CN 00262393
Authority: CN
Inventors: 张明娟; 杨军; 王康敏; 苏宝山; 黄莺; 赵世平
Original assignee: NO 2 HOSPITAL OF XI AN JIAOTON
Current assignee: NO 2 HOSPITAL OF XI AN JIAOTON
Priority date: 2000-11-17
Filing date: 2000-11-17
Publication date: 2001-09-19
Anticipated expiration: 2010-11-17

Abstract

The utility model relates to a utensil applied to the technical field of medical research, briefly, a tissue chip preparing apparatus. The utility model is composed of a fixing plate and a plurality of (more than two) hollow pipes with identical length, wherein the hollow pipes are mutually and parallelly penetrated and fixed to the fixing plate in a regular array form. The utility model can simply, conveniently and rapidly make a plurality of kinds of tissue samples or a plurality of tissue samples embedded on a wax block in a regular array form at the same time. Besides, the utility model can cut a plurality of kinds of tissue samples or a plurality of tissue sections, particularly tissue chips which are arranged in a regular array form. The utility model has the advantages of simple structure, convenient operation and low cost. The utility model can be used for various histological experiments.

Description

The organization chip preparing device

The utility model relates to a kind of utensil of using in the medical research field, briefly is a kind of organization chip preparing device.

Histopathology research is to support one of basis of whole medical development, and its research method also is the important research means of life science, and the achievement in research of any life science all needs the research of process techtology to add their confirmation and supports.Yet, be widely used in the histotomy in the medical research work, usually because can only embedding a kind of (individual) tissue samples in a wax stone, can only prepare the section that contains a tissue samples, promptly single histotomy.Thereby, even in the scientific research of the same detection index of carrying out a large amount of tissue samples, still must make a large amount of paraffin embedded tissues and histotomy, cause a large amount of wastes of experimental period, manpower and associated cost material and reagent, both consuming time, consumption power, also make in the same research artificial experimental error be difficult to avoid, the experiment comparability is reduced.And, widespread use along with genetic chip, protein chip, the new functional gene and the quantity of albumen also will roll up thereupon, and the further of its function determined, must get back to histological level again, connect with morphological structure, thereby the workload of Histological research is also incited somebody to action huge increasing thereupon, therefore, seek new Histopathology tabletting technology, the number of times, the raising conventional efficient that reduce experiment are very necessary.

The purpose of this utility model is to remedy above-mentioned the deficiencies in the prior art, and provide a kind of simple in structure, easy to operate organization chip preparing device, it can be embedded in same wax stone with multiple (individual) tissue samples (can reach tens of parts even increment up to a hundred originally) simultaneously, like this, each that cuts out is opened and is all included the tissue samples that multiple (individual) arranged with the array way of rule on the histotomy, be many histotomies, organization chip just, therefore, only need an experimental implementation to carry out the same detection Study of indexes to multiple (individual) tissue samples simultaneously.

The purpose of this utility model is achieved in that the hollow tubular of fixing many (more than two) equal length and being parallel to each other with the array way of rule on a fixed head, and hollow tubular runs through fixed head, the hollow tubular die is unobstructed, the number of hollow tubular and diameter according to the size of embedding frame and experiment to different requirement of tissue samples size and selection arbitrarily, fix a hollow tubular less at fixed head one jiao, with the order of a mark array.When making paraffin embedded tissues, produce the thin layer wax stone of thickness earlier less than 1cm, after treating that it solidifies, with its taking-up, place on the hardboard hand-held fixed head of the present utility model, hollow tubular is vertically inserted in the thin layer wax stone, and then slowly extract, like this, in the thin layer wax stone, can stay a plurality of duck eyes of arranging with the array way of rule.At this moment, select the suitable little block organization that has handled well, or utilize microscope that existing single histotomy is observed, select appropriate area, contrast its corresponding paraffin embedded tissues, take tissue in wherein the respective regions with hollow needle, the above-mentioned piece of tissue that chooses is put into successively the duck eye of thin layer wax stone, again the thin layer wax stone is put into the embedding frame, slowly add the special-purpose paraffin that melts, the array way of all fritter piece of tissue with rule can be fixed in the same wax stone after the cooling, it is taken out from the embedding frame, can obtain many paraffin embedded tissues.Each that cuts out is opened and is all included the tissue samples that multiple (individual) arranged with the array way of rule, i.e. organization chip on the histotomy thus.And, owing to fixed a hollow tubular less, thereby can tell putting in order of tissue samples in paraffin embedded tissues and the organization chip at fixed head one jiao fully aware ofly.

Take such scheme, can produce organization chip simply, quickly, therefore, only need an experimental implementation to carry out the same detection Study of indexes to multiple (individual) tissue samples simultaneously, and, personal error in single tissue samples operational processes factors such as (do not wait) application of sample are inaccurate be can obviously reduce, experimental period, human and material resources and reagent significantly saved as processing time, temperature.

The utility model is described in further detail below in conjunction with drawings and Examples.

Accompanying drawing and description of drawings:

Fig. 1 is the utility model structural representation.

Fig. 2 is the longitudinal profile structural map of Fig. 1.

Fig. 3 is I-I cut-open view of Fig. 1.

Among the figure: 1. hollow tubular, 2. fixed head, 3. hollow tubular die

Among the accompanying drawing 1 described embodiment, the hollow tubular of 119 equal length (1) is with the array way of rule and run through in parallel to each other and be fixed on the fixed head (2), and hollow tubular die (3) is unobstructed, fixes a hollow tubular (1) less at fixed head (2) one jiao.

The utility model compared with prior art has simple in structure, easy to operate, with low cost, real With advantages such as convenience, can be widely used in various histology experiments.

Claims

1. an organization chip preparing device is made up of many (more than two) hollow tubulars and fixed head, it is characterized in that: the hollow tubular of many (more than two) equal length is with the array way of rule and run through in parallel to each other and be fixed on the same fixed head.

2. according to claims 1 described organization chip preparing device, it is characterized in that: the hollow tubular die is unobstructed.

3. according to claims 1 described organization chip preparing device, it is characterized in that: fix a hollow tubular less at fixed head one jiao.

4. according to claims 1 described organization chip preparing device, it is characterized in that: the material of fixed head is a metal or nonmetal.