CN2325115Y - Apparatus for separating magnetic particles - Google Patents
Apparatus for separating magnetic particles Download PDFInfo
- Publication number
- CN2325115Y CN2325115Y CN 98204288 CN98204288U CN2325115Y CN 2325115 Y CN2325115 Y CN 2325115Y CN 98204288 CN98204288 CN 98204288 CN 98204288 U CN98204288 U CN 98204288U CN 2325115 Y CN2325115 Y CN 2325115Y
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- CN
- China
- Prior art keywords
- hole
- crane
- plate
- utility
- magnetic
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- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
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- Investigating Or Analysing Biological Materials (AREA)
Abstract
The utility model relates to a device for separating magnetic particles and biological samples or washing. A suction pump, a suction flask, an air extraction tube, a pipette, a basal plate, a lifting support, a 96 hole plate and an over magnetism plate are connected to form the utility model. The middle position of the basal plate is provided with a magnet, and the both sides of the magnet are provided with barrier strips, and the middle positions of the barrier strips are provided with upright posts which are sheathed with springs. Liquid extraction needle cylinders are evenly arranged on the bottom surface of the lifting support, and the upper ends of the liquid extraction needle cylinders are connected with a pipette end. A hole is arranged on the surface of the hole plate, a gap hole is arranged on a bottom surface, and a magnetic post is arranged on the over magnetism plate. The utility model has the advantages of simple structure, low cost, convenient operation and high separation or washing efficiency, and has the popularization value on the clinical application.
Description
The utility model relates to a kind of Medical Instruments, especially a kind of device that is used to separate magnetic-particle and biological sample or washing usefulness.
The immune clinical examination of carrying out in the hospital at present, usually adopt " immune enzyme linked immunosorbent assay ", magnetic grain and human body blood sample that utilization is wrapped with the high-molecular biologic film carry out hybrid reaction, if contain the antigen of antibody or pathogen in the blood of human body, can produce immune response with the biomolecule on magnetic grain surface, separate the residue serum that does not react then, carry out next step testing again.But this isolation technics work difficulty is bigger, and single manual operations is difficult to reach clinical requirement.Though existing abroad testing agency adopts a kind of full automatic separator, this apparatus cost costliness, the cost height is difficult for grasping and uses, and according to present domestic situation, is difficult to for the moment introduce and promotes the use of.
The purpose of this utility model be to provide a kind of simple in structure, manufacturing cost is low, the device of easy to operate, separation magnetic-particle that separative efficiency is high.
The purpose of this utility model is achieved in that a kind of device that separates magnetic-particle, it is by adjustable suction pump, bottle,suction, exhaust tube, pipette, substrate, crane, 96 orifice plates and super magnetic sheet assemble, its substrate middle part is embedded with magnet, both sides of the edge are provided with blend stop, the blend stop middle part is provided with column, be with spring on the column, the crane bottom surface is provided with the drawing liquid syringe of evenly vertically arranging, syringe upper end is connected with imbibition pipe end on being connected on crane, the crane two ends are provided with the perforation that can be inserted in base shaft, 96 orifice plates are contained on the real estate between the blend stop and can equidistantly move, the orifice plate face is provided with evenly distributed indent hole, the orifice plate bottom surface is provided with the indent mesopore of opening with indent hole difference, is adorning super magnetic sheet under 96 orifice plates, and the magnetic sheet face is provided with and can mates the magnetic post that embeds in the mesopore.
The utility model is simple in structure, and cost is low, and is easy to operate, can separate in batches or washing sample, and high efficiency has the clinical practice promotional value.
Below in conjunction with drawings and Examples in detail the utility model is described in detail.
Fig. 1 is the utility model structural representation.
Fig. 2 is 96 orifice plate upward views of the present utility model.
Shown in Fig. 1～2, a kind of device that separates magnetic-particle, it is by adjustable suction pump (1), bottle,suction (2), exhaust tube (3), pipette (4), substrate (5), crane (8), 96 orifice plates (13) and super magnetic sheet (16) assemble, it is characterized in that: substrate (5) middle part is embedded with magnet (10), both sides of the edge are provided with blend stop (9), blend stop (9) middle part is provided with column (11), be with spring (12) on the column (11), crane (8) bottom surface is provided with the drawing liquid syringe of evenly vertically arranging (7), syringe (7) upper end is held with the pipette (4) on being connected on crane (8) and is connected, crane (8) two ends are provided with the perforation (6) that can be inserted in base shaft (11), 96 orifice plates (13) are contained on substrate (5) face between two blend stops (9) and can equidistantly move, orifice plate (13) face is provided with evenly distributed indent hole (14), orifice plate (13) bottom surface is provided with the indent mesopore of opening with indent hole (14) difference (15), adorning super magnetic sheet (16) under 96 orifice plates (13), magnetic sheet (16) face is provided with and can mates the magnetic post (17) that embeds in the mesopore (15).During operation, with the human body check blood sample that extracts, be injected in the hole (14) of orifice plate (13), put into the magnetic grain that is wrapped with biomolecule in the hole (14) in advance, as having sick body in the blood sample, the biomolecule on it and magnetic grain surface is carried out immune response, then 96 orifice plates (13) are rested above the super magnetic sheet (16), magnetic post (17) on the super magnetic sheet (16) is inserted in the mesopore (15) of orifice plate (13) bottom surface, because the mutual attraction effect of magnetic, magnetic particle in the hole (14) is adsorbed on hole (14) wall, remaining responseless serum in the hole (14), again orifice plate (13) and super magnetic sheet (16) integral body are moved on substrate (5) face, open suction pump (1), crane (8) is enclosed within on the column (11) by perforation (6), depress crane (8), make in the interior serum solution of drawing liquid syringe (7) lower end patchhole plate holes (14), by pipette (4) responseless serum is drawn in the bottle,suction (2), stay the magnetic particle after the immune response in the hole (14), and then carry out next step testing.
Claims (1)
1. device that separates magnetic-particle, it is by adjustable suction pump (1), bottle,suction (2), exhaust tube (3), pipette (4), substrate (5), crane (8), 96 orifice plates (13) and super magnetic sheet (16) assemble, it is characterized in that: substrate (5) middle part is embedded with magnet (10), both sides of the edge are provided with blend stop (9), blend stop (9) middle part is provided with column (11), be with spring (12) on the column (11), crane (8) bottom surface is provided with the drawing liquid syringe of evenly vertically arranging (7), syringe (7) upper end is held with the pipette (4) on being connected on crane (8) and is connected, crane (8) two ends are provided with the perforation (6) that can be inserted in base shaft (11), 96 orifice plates (13) are contained on substrate (5) face between two blend stops (9) and can equidistantly move, orifice plate (13) face is provided with evenly distributed indent hole (4), orifice plate (13) bottom surface is provided with the indent mesopore of opening with indent hole (14) difference (15), adorning super magnetic sheet (16) under 96 orifice plates (13), magnetic sheet (16) face is provided with and can mates the magnetic post (17) that embeds in the mesopore (15).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 98204288 CN2325115Y (en) | 1998-05-19 | 1998-05-19 | Apparatus for separating magnetic particles |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 98204288 CN2325115Y (en) | 1998-05-19 | 1998-05-19 | Apparatus for separating magnetic particles |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN2325115Y true CN2325115Y (en) | 1999-06-23 |
Family
ID=33960923
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 98204288 Expired - Lifetime CN2325115Y (en) | 1998-05-19 | 1998-05-19 | Apparatus for separating magnetic particles |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN2325115Y (en) |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100542677C (en) * | 2006-10-16 | 2009-09-23 | 中国科学院过程工程研究所 | The continuous production equipment of biochemical product magnetic adsorption and desorption |
| CN101678364B (en) * | 2007-05-29 | 2013-12-04 | 生命技术股份公司 | A magnetic separating device |
| CN104697841A (en) * | 2015-03-30 | 2015-06-10 | 北京热景生物技术有限公司 | Magnetic particle separating and transferring device and method and application thereof |
| CN111097598A (en) * | 2019-12-26 | 2020-05-05 | 浙江雅顿环境科技有限公司 | Magnetic rod filter |
| CN111208192A (en) * | 2020-01-15 | 2020-05-29 | 中国科学院生态环境研究中心 | Magnetic Fe in the environment3O4Circulating enrichment device for separating and extracting nano particles and detection method thereof |
| CN113145297A (en) * | 2009-05-15 | 2021-07-23 | 简·探针公司 | Method and apparatus for implementing automatic movement of a magnet in an instrument performing a magnetic separation procedure |
-
1998
- 1998-05-19 CN CN 98204288 patent/CN2325115Y/en not_active Expired - Lifetime
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100542677C (en) * | 2006-10-16 | 2009-09-23 | 中国科学院过程工程研究所 | The continuous production equipment of biochemical product magnetic adsorption and desorption |
| CN101678364B (en) * | 2007-05-29 | 2013-12-04 | 生命技术股份公司 | A magnetic separating device |
| CN113145297A (en) * | 2009-05-15 | 2021-07-23 | 简·探针公司 | Method and apparatus for implementing automatic movement of a magnet in an instrument performing a magnetic separation procedure |
| CN113145297B (en) * | 2009-05-15 | 2023-09-29 | 简·探针公司 | Method and apparatus for automatic movement of magnet in instrument for performing magnetic separation process |
| CN104697841A (en) * | 2015-03-30 | 2015-06-10 | 北京热景生物技术有限公司 | Magnetic particle separating and transferring device and method and application thereof |
| CN104697841B (en) * | 2015-03-30 | 2021-01-12 | 北京热景生物技术股份有限公司 | Magnetic particle separation and transfer device, method and application thereof |
| CN111097598A (en) * | 2019-12-26 | 2020-05-05 | 浙江雅顿环境科技有限公司 | Magnetic rod filter |
| CN111208192A (en) * | 2020-01-15 | 2020-05-29 | 中国科学院生态环境研究中心 | Magnetic Fe in the environment3O4Circulating enrichment device for separating and extracting nano particles and detection method thereof |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C56 | Change in the name or address of the patentee |
Owner name: SHANGHAI HAOYUAN BIOLOGY SCIENCE CO., LTD. Free format text: FORMER NAME OR ADDRESS: WANG ZHAOHUI; HUANG DAOPEI |
|
| CP03 | Change of name, title or address |
Address after: 202106, Huang Jiexin, 1998 Jinqiao Road, Shanghai, Pudong New Area Patentee after: Shanghai Haoyuan Biotechnology Co., Ltd. Address before: 200233 Shanghai City, Guiping Road No. 495 Building No. 15 5B2 sea Haoyuan biotechnology company Patentee before: Wang Zhaohui Patentee before: Huang Daopei |
|
| C17 | Cessation of patent right | ||
| CX01 | Expiry of patent term |