CN220894114U - Modularized fluorescence analysis and detection device - Google Patents
Modularized fluorescence analysis and detection device Download PDFInfo
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- CN220894114U CN220894114U CN202322311815.9U CN202322311815U CN220894114U CN 220894114 U CN220894114 U CN 220894114U CN 202322311815 U CN202322311815 U CN 202322311815U CN 220894114 U CN220894114 U CN 220894114U
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- 238000012921 fluorescence analysis Methods 0.000 title claims abstract description 32
- 238000001917 fluorescence detection Methods 0.000 title description 4
- 238000001514 detection method Methods 0.000 claims abstract description 60
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- 230000001360 synchronised effect Effects 0.000 claims description 12
- 238000012360 testing method Methods 0.000 claims description 12
- 238000004458 analytical method Methods 0.000 abstract description 12
- 238000013461 design Methods 0.000 abstract description 3
- 239000000126 substance Substances 0.000 description 17
- 238000011160 research Methods 0.000 description 4
- 238000010223 real-time analysis Methods 0.000 description 3
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- 238000005516 engineering process Methods 0.000 description 2
- 230000007613 environmental effect Effects 0.000 description 2
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Abstract
The utility model discloses a modularized fluorescence analysis detection device, which comprises: a moving mechanism and a detecting mechanism. The moving mechanism is in driving connection with the detecting mechanism, the detecting mechanism comprises an adjustable supporting rod, a light path adjusting block and a pressing block, the top end of the adjustable supporting rod is fixedly connected with the pressing block, the bottom end of the adjustable supporting rod is fixedly connected with the top end of the light path adjusting block, a detecting unit mounting hole and a light source emitting hole which are vertically communicated are formed in the light path adjusting block, a detecting unit is arranged in the detecting unit mounting hole, a light source emitting unit is arranged in the light source emitting hole, and a first light path adjusting groove is formed in the bottom end of the light source emitting hole. The modularized design of the modularized fluorescence analysis detection device solves the technical problems of heavy, complex, huge volume, high cost and lack of flexibility and expandability of a fluorescence analysis instrument in the technical field of biological analysis in the prior art.
Description
Technical Field
The utility model relates to the technical field of biological analysis, in particular to a modularized fluorescence analysis detection device.
Background
Along with the rapid development of bioscience, medical research and life science, fluorescence analysis plays an important role as a common technical means in the fields of molecular biology, medical diagnosis, drug research and development and the like. Fluorescent analysis is an important biological analysis technology, and can quantitatively detect and measure target molecules or substances existing in a sample by exciting fluorescent substances and measuring spectral characteristics of the fluorescent substances emitted by the fluorescent substances, and is widely applied to the fields of life science research, medicine field, environmental monitoring and the like.
However, conventional fluorescence analysis instruments are often cumbersome, complex, bulky, and costly, and lack flexibility and scalability issues. These instruments often require a series of accessories and specialized equipment to meet different analysis requirements, limiting their use in the field of real-time analysis and portable detection due to the lack of flexibility and portability of these instruments.
Disclosure of utility model
The utility model aims to overcome the technical defects, provide a modularized fluorescence analysis detection device and solve the technical problems of heavy, complex, huge volume, high cost and lack of flexibility and expandability of a fluorescence analysis instrument in the technical field of biological analysis in the prior art.
In order to achieve the above technical object, the present utility model provides a modularized fluorescence analysis and detection device, comprising:
moving mechanism
The detection mechanism is in driving connection with the detection mechanism and comprises an adjustable support rod, an optical path adjusting block and a pressing block; the top end of the adjustable supporting rod is fixedly connected with the pressing block; the bottom end of the adjustable support rod is fixedly connected with the top end of the light path adjusting block; the light path adjusting block is provided with a detection unit mounting hole which is vertically communicated with the light path adjusting block and a light source emitting hole; a detection unit is arranged in the detection unit mounting hole; and a light source emitting unit is arranged in the light source emitting hole.
Compared with the prior art, the utility model has the beneficial effects that:
1. Flexibility and customizable: the modularized fluorescence analysis detection device provided by the utility model can be flexibly configured and customized according to specific analysis requirements. By combining different modules, a user can select and match each component as needed to meet different sample types, analysis targets and research requirements.
2. High efficiency and accuracy: the modularized design of the modularized fluorescence analysis detection device provided by the utility model can provide higher analysis efficiency and result accuracy, and different modules can perform parallel processing, multichannel analysis or high-throughput experiments, so that the analysis speed is increased, the sample processing time is shortened, and the data quality and the reproducibility of the experiments are improved.
3. Portability and real-time analysis: the modular fluorescence analysis detection apparatus provided by the present utility model generally has a smaller size and lighter construction than conventional cumbersome instruments. This makes the device easier to carry and move, enabling it to function in on-site real-time analysis and portable detection applications, such as field sample collection, real-time monitoring, etc.
4. Extensibility and upgradeability: the modularized design of the modularized fluorescence analysis detection device provided by the utility model provides good expandability and upgradeability for the fluorescence analysis detection device, and along with the development of technology and the change of research demands, a user can conveniently add new modules or replace the existing modules so as to realize new functions or meet new analysis requirements without replacing the whole device.
Drawings
FIG. 1 is a schematic perspective view of a modular fluorescence analysis testing device according to the present utility model;
FIG. 2 is a schematic perspective view of a modular fluorescence analysis testing device according to the present utility model;
FIG. 3 is a schematic perspective view of a detection base plate of the modularized fluorescence analysis detection device;
FIG. 4 is a schematic perspective view of an optical path adjusting block of the modularized fluorescence analysis detecting device;
FIG. 5 is a schematic cross-sectional view of a modular fluorescence analysis testing device provided by the present utility model;
Fig. 6 is a schematic diagram of the bottom structure of the modular fluorescence analysis detecting apparatus provided by the present utility model.
Detailed Description
The present utility model will be described in further detail with reference to the drawings and examples, in order to make the objects, technical solutions and advantages of the present utility model more apparent. It should be understood that the specific embodiments described herein are for purposes of illustration only and are not intended to limit the scope of the utility model.
It will be understood that when an element is referred to as being "fixed to" another element, it can be directly on the other element or intervening elements may also be present. When an element is referred to as being "connected" to another element, it can be directly connected to the other element or intervening elements may also be present. The terms "vertical," "horizontal," "left," "right," and the like are used herein for illustrative purposes only and are not meant to be the only embodiment.
Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this utility model belongs. The terminology used herein in the description of the utility model is for the purpose of describing particular embodiments only and is not intended to be limiting of the utility model. The term "and/or" as used herein includes any and all combinations of one or more of the associated listed items.
Referring to fig. 1, 2, 3, 4, 5 and 6, the present embodiment provides a modularized fluorescence analysis and detection device, which includes: a moving mechanism 1 and a detecting mechanism 2.
The moving mechanism 1 is in driving connection with the detecting mechanism 2.
Further, the detection mechanism 2 comprises an adjustable support rod 21, an optical path adjusting block 22 and a pressing block 23. In the present embodiment, the optical path adjusting block 22 mainly plays a role in adjusting the installation of the detecting unit 24, the installation of the light source emitting unit 25, the optical path of the light source emitting unit 25, and the optical path of the reflected light source. The top of adjustable bracing piece 21 with briquetting 23 fixed connection, the bottom of adjustable bracing piece 21 with the top fixed connection of light path adjustment piece 22, light path adjustment piece 22 has seted up detection unit mounting hole 22a and light source emission hole 22b that link up from top to bottom, install in the detection unit mounting hole 22a detection unit 24, install in the light source emission hole 22b light source emission unit 25, first light path adjustment groove 22c has been seted up to the bottom of light source emission hole 22 b.
Specifically, when the height of the optical path adjusting block 22 needs to be adjusted, the height of the optical path adjusting block 22 is adjusted by the adjustable support bar 21.
Preferably, the four light source emitting holes 22b are disposed symmetrically about a central line of the light path adjusting block 22, the light source emitting holes 22b form a certain angle with the horizontal plane, the light source emitting units 25 are disposed in the light source emitting holes 22b, and the light source emitting units 25 emit light sources to irradiate the surface 3 of the substance to be detected after being adjusted by the first light path adjusting groove 22c, and because the two light source emitting holes 22b are symmetrical about the central line of the light path adjusting block 22 and form a certain angle with the horizontal plane, that is, when one group of light source emitting units 25 emit light beams obliquely irradiates a point on the surface of the substance to be detected, one side of the irradiation point far away from the light source emitting units 25 is weaker in light receiving, and at the moment, the other group of light source emitting units 25 emit light beams irradiating the same point, so that complementation of light source irradiation is realized, and the light sources of the irradiation points are sufficient and uniform.
Further, the detection mechanism 2 further includes a detection bottom plate 26 and a detection base 27, the detection bottom plate 26 is located below the optical path adjusting block 22, the detection bottom plate 26 is fixed above the detection base 27, a first detection groove 26a is formed in the detection bottom plate 26, and a second detection groove 26b is formed in the bottom end of the first detection groove 26 a.
Preferably, the width of the first detecting groove 26a is larger than the width of the second detecting groove 26b, and the first detecting groove 26a is used for positioning and accommodating the substance to be detected.
The moving mechanism 1 comprises a moving driving source 11, a linear guide rail 12, a moving sliding block 13, a driving wheel 14 and a synchronizing wheel 15, wherein an output shaft of the moving driving source 11 is in driving connection with the driving wheel 14, the linear guide rail 12 is fixed on one side of the detection base 27, the upper end of the moving driving source 11 fixed on the detection base 27 is positioned at one end of the linear guide rail 12, the synchronizing wheel 15 is fixed on the other end of the linear guide rail 12 through a bearing support 16, and the bearing support 16 is fixed on the upper end of the detection base 27.
Preferably, the moving driving source 11 is selected as a servo motor, wherein the servo motor has the following advantages: 1. high precision: the servo motor can achieve very high position and speed control precision, and generally has micrometer-level positioning precision; 2. high responsiveness: the response speed of the servo motor is very high, and the servo motor can be quickly adjusted and responded within millisecond level; 3. self-detection and fault protection functions: the servo motor generally has self-diagnosis and fault protection functions, can automatically detect system abnormality and take measures to protect, and improves the reliability and safety of the system.
Further, the movable slider 13 is slidably connected with the linear guide rail 11, the driving wheel 14 is in driving connection with the synchronizing wheel 15 through a synchronous belt 17, and the upper end of the movable slider 13 is fixedly connected with the synchronous belt 17.
Further, a connection plate 18 is fixedly connected to one side of the movable slider 13, and an upper end of the connection plate 18 is fixedly connected to one side of the pressing block 23.
Specifically, when the substance to be detected is fixed in the first detection groove 26a and is detected, the moving driving source 11 works to drive the driving wheel 14 to rotate, so as to realize rotation of the synchronous belt 17, and the synchronous belt 17 and the pressing block 23 are fixedly connected through the connecting plate 18, so that the optical path adjusting block 22 moves back and forth along the linear guide 11 on the basis of the moving slide 13, and the detecting unit 24 and the light source emitting unit 25 continuously work in the moving process, that is, the four light source emitting units 25 perform back and forth beam scanning on the surface of the substance to be detected, and the detecting unit 24 performs back and forth detection on the substance to be detected.
Further, the detection bottom plate 26 has a window structure, and a guiding and fixing slot is formed in the detection bottom plate for fixing the substance to be detected in the first detection slot 26 a.
Further, a second light path adjusting groove 22d is formed at the lower end of the detecting unit mounting hole 22a, a collecting lens mounting hole 23a and the counterweight mounting hole 23b are formed in the pressing block 23, and a weight reducing groove 22e is formed at the bottom end of the light path adjusting block 22.
Specifically, the collecting lens mounting hole 23a is used for mounting a lens in the later stage, and the counterweight mounting hole 23b is used for adding a counterweight in the later stage.
Specifically, when the light source emitting unit 25 emits a light beam to the detected substance, the detected substance emits fluorescence of a specific wavelength, and the fluorescence enters the detecting unit 24 after being adjusted by the second light path adjusting groove 22 d. The first light path adjusting groove 22c and the second light path adjusting groove 22d are used for adjusting the light path, and the purpose of the light path adjustment is to ensure that the light can accurately enter and be transmitted into the sample or the detector so as to obtain an accurate fluorescent signal. The object of the light path adjustment includes: 1. ensure the focusing and alignment of the light rays: the light can be focused to a required position through light path adjustment, and the optical path between the light and the sample is aligned, so that the light can be ensured to accurately irradiate the surface of the sample, and an accurate fluorescent signal can be obtained; 2. maximizing the collection efficiency of light: adjusting the light path to optimize the collection efficiency of the light, so that as much fluorescent signal as possible can be received by the detector, which may involve selecting appropriate optical elements, adjusting the angle and path of incidence of the light, etc.; 3. removing interference signals: interference signals from other light sources or environmental factors are excluded by adjusting the light path to ensure that only fluorescent signals from the sample are detected. In summary, the purpose of the light path adjustment is to ensure that light can properly enter and be transmitted to the sample or detector to obtain an accurate and reliable fluorescent signal, and by means of the accurate light path adjustment, the fluorescence analysis detection device can improve the accuracy and reliability of the measurement.
Further, an anti-collision buffer unit 19 is fixedly connected to one end of the linear guide rail 12, which is close to the moving driving source 11.
Specifically, when the movable slider 13 moves to a position close to the end of the movable driving source 11, in order to prevent the movable slider 13 from colliding with the movable driving source 11, the anti-collision buffer unit 19 is fixedly connected to the end of the linear guide 12 close to the movable driving source 11, so as to ensure the safety of the device.
Preferably, the crash cushion unit 19 is selected to be a steel spring.
Working principle: the utility model provides a modularized fluorescence analysis detection device, comprising: a moving mechanism 1 and a detecting mechanism 2. The moving mechanism 1 is in driving connection with the detecting mechanism 2, the detecting mechanism 2 comprises an adjustable supporting rod 21, a light path adjusting block 22 and a pressing block 23, the top end of the adjustable supporting rod 21 is fixedly connected with the pressing block 23, the bottom end of the adjustable supporting rod 21 is fixedly connected with the top end of the light path adjusting block 22, the light path adjusting block 22 is provided with a detecting unit mounting hole 22a and a light source emitting hole 22b which are vertically communicated, a detecting unit 24 is arranged in the detecting unit mounting hole 22a, a light source emitting unit 25 is arranged in the light source emitting hole 22b, and a first light path adjusting groove 22c is formed in the bottom end of the light source emitting hole 22 b. Specifically, when the substance to be detected is fixed in the first detection groove 26a, the light source emitting unit 25, the detecting unit 24 and the moving driving source 11 are started, the moving driving source 11 drives the driving wheel 14 to rotate, the synchronous belt 17 rotates on the basis of the synchronous wheel 15, and the light path adjusting block 22 is fixedly connected with the synchronous belt 17 through the pressing block 23 and the connecting plate 18, so that when the synchronous belt 17 rotates, the light path adjusting block 22 moves back and forth above the substance to be detected, at this time, the light source emitting unit 25 emits a light beam to the surface of the substance to be detected, and the detecting unit 24 detects on the surface of the substance 3 to be detected.
The above-described embodiments of the present utility model do not limit the scope of the present utility model. Any other corresponding changes and modifications made in accordance with the technical idea of the present utility model shall be included in the scope of the claims of the present utility model.
Claims (7)
1. A modular fluorescence analysis testing device, comprising:
moving mechanism
The detection mechanism is in driving connection with the detection mechanism and comprises an adjustable support rod, an optical path adjusting block and a pressing block; the top end of the adjustable supporting rod is fixedly connected with the pressing block; the bottom end of the adjustable support rod is fixedly connected with the top end of the light path adjusting block; the light path adjusting block is provided with a detection unit mounting hole which is vertically communicated with the light path adjusting block and a light source emitting hole; a detection unit is arranged in the detection unit mounting hole; a light source emitting unit is arranged in the light source emitting hole; the bottom of the light source emitting hole is provided with a first light path adjusting groove.
2. The modular fluorescence analysis testing device of claim 1, wherein the testing mechanism further comprises a testing base plate, a testing base; the detection bottom plate is positioned below the light path adjusting block; the detection bottom plate is fixed above the detection base; the detection bottom plate is provided with a first detection groove; the bottom of the first detection groove is provided with a second detection groove.
3. The modular fluorescence analysis testing device of claim 2, wherein the movement mechanism comprises a movement drive source, a linear guide, a movement slide, a drive wheel, a synchronizing wheel; an output shaft of the mobile driving source is in driving connection with the driving wheel; the linear guide rail is fixed on one side of the detection base; the upper end of the movable driving source, which is fixed on the detection base, is positioned at one end of the linear guide rail; the synchronous wheel is fixed at the other end of the linear guide rail through a bearing support; the bearing support is fixed at the upper end of the detection base.
4. The modular fluorescence analysis testing device of claim 3, wherein the movable slider is slidably coupled to the linear guide; the driving wheel is in driving connection with the synchronous wheel through a synchronous belt; the upper end of the movable sliding block is fixedly connected with the synchronous belt.
5. The modular fluorescence analysis testing device of claim 4, wherein a connecting plate is fixedly connected to one side of the movable slider; the upper end of the connecting plate is fixedly connected with one side of the pressing block.
6. The modular fluorescence analysis detecting apparatus according to claim 5, wherein a second light path adjustment groove is provided at a lower end of the detection unit mounting hole; the pressing block is provided with an acquisition lens mounting hole and a counterweight mounting hole; the bottom of the light path adjusting block is provided with a weight reducing groove.
7. The modular fluorescence analysis testing device of claim 3, wherein the linear guide is fixedly connected with an anti-collision buffer unit at one end of the linear guide near the mobile drive source.
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| Application Number | Priority Date | Filing Date | Title |
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| CN202322311815.9U CN220894114U (en) | 2023-08-25 | 2023-08-25 | Modularized fluorescence analysis and detection device |
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| Application Number | Priority Date | Filing Date | Title |
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| CN202322311815.9U CN220894114U (en) | 2023-08-25 | 2023-08-25 | Modularized fluorescence analysis and detection device |
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| CN220894114U true CN220894114U (en) | 2024-05-03 |
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| CN202322311815.9U Active CN220894114U (en) | 2023-08-25 | 2023-08-25 | Modularized fluorescence analysis and detection device |
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- 2023-08-25 CN CN202322311815.9U patent/CN220894114U/en active Active
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