CN220724202U - Auxiliary liquid feeding device for embryo culture - Google Patents
Auxiliary liquid feeding device for embryo culture Download PDFInfo
- Publication number
- CN220724202U CN220724202U CN202322370245.0U CN202322370245U CN220724202U CN 220724202 U CN220724202 U CN 220724202U CN 202322370245 U CN202322370245 U CN 202322370245U CN 220724202 U CN220724202 U CN 220724202U
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- Prior art keywords
- culture
- liquid outlet
- outlet pipe
- liquid
- filling
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- 239000007788 liquid Substances 0.000 title claims abstract description 79
- 210000001161 mammalian embryo Anatomy 0.000 title claims abstract description 23
- 210000002257 embryonic structure Anatomy 0.000 abstract description 3
- 208000033641 Ring chromosome 5 syndrome Diseases 0.000 description 6
- 239000012530 fluid Substances 0.000 description 5
- 238000000034 method Methods 0.000 description 5
- 238000005516 engineering process Methods 0.000 description 4
- 230000001850 reproductive effect Effects 0.000 description 4
- 239000003814 drug Substances 0.000 description 3
- 241000282414 Homo sapiens Species 0.000 description 2
- 241001465754 Metazoa Species 0.000 description 2
- 235000015097 nutrients Nutrition 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 241000894006 Bacteria Species 0.000 description 1
- 241000282412 Homo Species 0.000 description 1
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 1
- 230000004888 barrier function Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000001276 controlling effect Effects 0.000 description 1
- 239000012531 culture fluid Substances 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000009792 diffusion process Methods 0.000 description 1
- 235000013601 eggs Nutrition 0.000 description 1
- 230000008020 evaporation Effects 0.000 description 1
- 238000001704 evaporation Methods 0.000 description 1
- 230000002349 favourable effect Effects 0.000 description 1
- 230000004720 fertilization Effects 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 208000000509 infertility Diseases 0.000 description 1
- 230000036512 infertility Effects 0.000 description 1
- 231100000535 infertility Toxicity 0.000 description 1
- 230000009027 insemination Effects 0.000 description 1
- 244000144972 livestock Species 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000003204 osmotic effect Effects 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 238000005086 pumping Methods 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 239000000741 silica gel Substances 0.000 description 1
- 229910002027 silica gel Inorganic materials 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P60/00—Technologies relating to agriculture, livestock or agroalimentary industries
- Y02P60/20—Reduction of greenhouse gas [GHG] emissions in agriculture, e.g. CO2
- Y02P60/21—Dinitrogen oxide [N2O], e.g. using aquaponics, hydroponics or efficiency measures
Abstract
The utility model aims to provide an embryo culture auxiliary liquid adding device, which relates to the technical field of embryo culture auxiliary equipment, and the speed of filling culture oil liquid is increased by arranging a plurality of liquid outlet pipes on the circumference of a mounting plate of a filling head, so that the filled culture oil liquid is more uniform; the control ring is driven to slide up and down by rotating the adjusting nut, the control rope is driven to pull the liquid outlet pipe to slide, and the liquid outlet pipe is controlled to slide in an auxiliary mode by the aid of the first elastic element arranged in the sliding groove, so that the liquid outlet pipe of the circumferential array can adapt to culture dishes with different diameters, the liquid outlet pipe is close to the edge of the inner wall of the culture dish, culture oil is injected along the edge of the inner wall of the culture dish, and impact on embryos is reduced; the second elastic element of the clamping assembly is propped against the clamping block arranged on the inner circumference array of the placing groove to contact the outer wall of the culture dish in the way that the circle center is contracted, the culture dish is clamped and fixed at the center of the placing groove, the filling head is aligned with the culture dish, manual calibration is not needed, and the filling efficiency is improved.
Description
Technical Field
The utility model relates to the technical field related to embryo culture auxiliary equipment, in particular to an embryo culture auxiliary liquid adding device.
Background
Embryo culture technology is a modern biotechnology, is widely applied to laboratories and clinical environments, and provides important support for the field of reproduction of humans and animals. The technique makes the embryo develop continuously in the laboratory by placing fertilized eggs or early embryo in culture solution containing rich nutrient substances and controlling proper culture conditions. It has many applications, including human assisted reproductive technologies (such as in vitro fertilization and embryo transfer) and animal reproduction (such as artificial insemination and embryo transfer); the development of embryo culture technology has important significance in solving the problem of infertility of human beings, promoting the propagation of livestock and the like. The technology utilizes nutrient substances in the culture solution to provide sufficient growth environment for the embryo, and promotes the normal development of the embryo by regulating parameters (such as temperature, humidity, pH value, gas concentration and the like) in the culture condition;
in the embryo culture process, it is generally necessary to add an appropriate amount of culture oil to the culture dish in order to maintain the stability of the culture solution. The main purpose of this step is to prevent evaporation of the broth while maintaining a relatively stable temperature, pH, osmotic pressure of the broth. The culture oil is favorable for separating the culture solution from air, and reduces pollution of bacteria, mold and particles in the culture box and the air to liquid drops; a stable gas diffusion barrier is also provided to help maintain the gas concentration in the embryo culture environment.
The utility model patent with the publication number of CN218666100U discloses a reproductive medicine liquid adding device, which comprises a workbench, a conveyor and a vertical plate, wherein the conveyor is arranged on the upper surface of the workbench, the vertical plate is assembled in the middle of one side of the workbench, an adjustable part is arranged at the top end of the vertical plate, a filling part is correspondingly arranged on the adjustable part, and the output end of the filling part faces the conveyor.
The culture dish that prior art will need to annotate is put one by one and is carried on the conveyer, and then form continuous stable filling work, with the help of the filling part can be continuous stable to the culture dish internal filling cultivate fluid, convenient and fast need not the staff and carries out manual filling, and with the help of adjusting part, can be quick carry out fine setting operation to the position of filling and filling height, make the culture fluid can carry out stable filling, whole filling scope has been enlarged, the whole operable range of equipment has been enlarged, but still there is following problem:
1. in the reproductive medicine liquid adding device in the prior art (CN 218666100U), when liquid is added, the liquid adding pipe of the liquid adding part can only realize single-point liquid adding, and culture oil can not be quickly and uniformly added into the culture dish;
2. the reproductive medicine liquid adding device of the prior art (CN 218666100U) is characterized in that the culture dishes are placed on the conveyor one by one to be conveyed, the filling part is aligned, the alignment process consumes time, the filling part can only fill one culture dish at a time, and the filling efficiency is low.
Disclosure of Invention
Aiming at the defects of the prior art, the utility model provides the following technical scheme:
the auxiliary liquid adding device for embryo culture comprises a fixed base, a supporting base and a filling part, wherein a supporting column is arranged on the supporting base, a movable ring is sleeved on the supporting column in a sliding manner, the filling part is slidably mounted on the supporting column through a circumferential array of the movable ring, the filling part comprises a supporting arm and a filling head, an adjusting nut is connected onto the supporting arm in a threaded manner, a control ring is movably sleeved on the adjusting nut, the upper end of the control ring is abutted to the lower end of the adjusting nut, the filling head comprises a control rope, a mounting plate and a liquid outlet pipe, one end of the supporting arm is connected with the movable ring, one end of the supporting arm is connected with the mounting plate, a plurality of sliding grooves are formed in the mounting plate along the circumference of a radius, one end of the liquid outlet pipe is slidably mounted in the sliding grooves through a sliding manner, one end of the control rope is connected with the control ring through a through hole in the mounting plate, the sliding groove is connected with one end of the liquid outlet pipe through a sliding block, the control ring is driven to slide up and down by rotating the adjusting nut, the control rope is driven to slide the liquid outlet pipe, and the liquid outlet pipe is controlled to slide in an auxiliary manner through a first elastic element arranged in the sliding groove;
the support base is provided with a placing groove, a clamping assembly is arranged in the placing groove, the clamping assembly comprises a second elastic element and a plurality of telescopic rods which are arrayed along the circumference of the side wall of the placing groove, one end of each telescopic rod is fixedly connected with the side wall of the placing groove, the other end of each telescopic rod is provided with a clamping block, and the telescopic rods are controlled to stretch out and draw back through the second elastic element.
Further, a liquid adding bin is arranged on the supporting arm, a liquid suction pump is arranged on the liquid adding bin, and the liquid suction pump is connected with a liquid outlet pipe on the mounting plate through a guide pipe.
Further, a rack is arranged on the support column, a motor and a gear meshed with the rack are arranged on the movable ring, the gear is driven to rotate by the motor, and the movable ring is controlled to slide on the support column.
Further, the fixed base is rotatably installed below the supporting base.
Further, the lower outer edge of the adjusting nut is of a laterally convex annular structure, and the upper inner edge of the control ring is of an inwardly convex annular structure.
Compared with the prior art, the technical scheme of the application has the following beneficial effects:
1. according to the utility model, the plurality of liquid outlet pipes are circumferentially arrayed on the mounting plate of the filling head, so that the speed of filling culture oil is increased, the filled culture oil is more uniform, and the problem that the liquid inlet pipe of the liquid inlet part can only realize single-point liquid inlet and can not enable the culture oil to be quickly and uniformly filled into the culture dish when the liquid is fed in the prior art (CN 218666100U) is solved;
2. according to the utility model, the plurality of liquid outlet pipes are circumferentially arranged on the mounting plate of the filling head, the liquid outlet pipes can slide in the sliding grooves of the mounting plate, the control ring is driven to slide upwards by rotating the adjusting nut, the control rope is driven to pull the liquid outlet pipes to move towards the circle center in a shrinkage mode, the liquid outlet pipes are supported in an auxiliary mode through the first elastic elements arranged in the sliding grooves, the liquid outlet pipes are outwards expanded to move under the elastic action of the first elastic elements by reversing the adjusting nut, the control ring is pulled to slide downwards, so that the liquid outlet pipes of the circumferential array can adapt to culture dishes with different diameters, the moving ring is controlled to move downwards by the motor driving gear, the liquid outlet pipes can be close to the edges of the inner walls of the culture dishes, so that culture oil is injected along the edges of the inner walls of the culture dishes, and the impact on embryos is reduced;
3. according to the utility model, the holding groove is formed in the support base, the holding blocks arranged in the inner circumference array of the holding groove are abutted against the second elastic element of the holding assembly to make contact with the outer wall of the culture dish in the manner of contracting towards the circle center, and the culture dish is held and fixed in the center of the holding groove, so that the filling head is aligned with the culture dish, the manual calibration is reduced, the filling efficiency is improved, the problems that in the prior art (CN 218666100U), the culture dishes are conveyed one by one on the conveyor, the filling part is aligned, the time is consumed in the alignment process, only one culture dish can be filled by the filling part at one time, and the filling efficiency is low are solved.
Drawings
FIG. 1 is a schematic view of a three-dimensional structure of the present utility model;
FIG. 2 is a schematic illustration of the structure of the filling member of the present utility model;
FIG. 3 is a schematic cross-sectional view of a fill head of the present utility model;
FIG. 4 is an enlarged schematic view of a portion of a cross-sectional structure of a fill head of the present utility model;
FIG. 5 is a schematic view of a half-section of a fill head of the present utility model;
FIG. 6 is a schematic cross-sectional view of an adjustment nut and control ring of the present utility model;
FIG. 7 is a schematic view of a placement hole according to the present utility model;
FIG. 8 is a schematic view of a clamping assembly according to the present utility model;
FIG. 9 is a schematic view of the bottom structure of the mounting plate of the present utility model.
In the figure: support base-1, standing groove-101, fixed base-2, clamping component-3, clamping block-301, second elastic element-302, telescopic rod-303, support column-4, rack-401, moving ring-5, motor-501, gear-502, filling head-6, control rope-601, scale-6011, mounting plate-602, through hole-6021, sliding groove-6022, drain pipe-603, roller-604, slider-605, first elastic element-606, liquid suction pump-7, conduit-8, support arm-9, adjusting nut-901, control ring-902 and liquid feeding bin-10.
Detailed Description
The following description of the embodiments of the present utility model will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present utility model, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the utility model without making any inventive effort, are intended to be within the scope of the utility model.
Example 1:
referring to fig. 1-9, an embryo culture auxiliary liquid feeding device comprises a fixed base 2, a supporting base 1 and a filling part, wherein the fixed base 2 is rotatably installed below the supporting base 1, a supporting column 4 is arranged on the supporting base 1, a movable ring 5 is sleeved on the supporting column 4 in a sliding manner, the filling part is slidably installed on the supporting column 4 through a circumferential array of the movable ring 5, a rack 401 is arranged on the supporting column 4, a motor 501 and a gear 502 meshed with the rack 401 are arranged on the movable ring 5, the filling part comprises a supporting arm 9 and a filling head 6, an adjusting nut 901 is connected on the supporting arm 9 in a threaded manner, a control ring 902 is movably sleeved on the adjusting nut 901, as shown in fig. 5 and 6, the outer edge below the adjusting nut 901 is of a laterally convex annular structure, the inner edge above the control ring 902 is of an inwardly convex annular structure, the lower part of the inner convex ring-shaped structure of the upper inner edge of the control ring 902 is abutted against the upper part of the side convex ring-shaped structure of the lower outer edge of the adjusting nut 901, the filling head 6 comprises a control rope 601, a mounting plate 602 and a liquid outlet pipe 603, one end of a supporting arm 9 is fixedly connected with the movable ring 5, the other end of the supporting arm is fixedly connected with the mounting plate 602, a plurality of sliding grooves 6022 are arrayed on the mounting plate 602 along the radius circumference, one end of the liquid outlet pipe 603 is slidably mounted in the sliding grooves 6022 through a sliding block 605, one end of the control rope 601 is connected with the control ring 902, the other end of the control rope passes through a through hole 6021 on the mounting plate 602 to reach the sliding groove 6022 and is connected with the sliding block 605 at one end of the liquid outlet pipe 603, a liquid adding bin 10 is arranged on the supporting arm 9, a liquid sucking pump 7 is arranged on the liquid adding bin 10, and the liquid sucking pump 7 is connected with the liquid outlet pipe 603 on the mounting plate 602 through a guide pipe 8;
in this embodiment, the liquid suction pump 7 is a prior art, and is used in daily life, such as a water dispenser for quantitatively pumping, a common micro pump type, for example, a micro plunger pump of Ismatec MCP-Z type, a micro gear pump of Micropump GJ-N type, and a micro membrane pump of KNF NMP03 type. The oil can be quantitatively extracted for a plurality of times, and the device has small volume.
In this embodiment, through a plurality of drain pipes 603 of circumference array on the mounting panel 602 of filling head 6, cultivate fluid can follow a plurality of drain pipes 603 and annotate in the culture dish for the speed of filling cultivate fluid, the cultivate fluid of filling is more even, has solved prior art (CN 218666100U) when the liquid feeding, the liquid feeding pipe of liquid feeding part only can realize single-point liquid feeding, can not make the quick even problem of filling to the culture dish of cultivate fluid.
Example 2:
referring to fig. 1-9, according to embodiment 1, a plurality of liquid outlet pipes 603 are circumferentially arrayed on a mounting plate 602 of a filling head 6, the liquid outlet pipes 603 can slide in a sliding groove 6022 of the mounting plate 602, a control ring 902 is driven to slide upwards by rotating an adjusting nut 901, a control rope 601 is driven to pull the liquid outlet pipes 603 to move towards the circle center in a shrinkage mode, the liquid outlet pipes 603 are supported by aid of a first elastic element 606 arranged in the sliding groove 6022, the liquid outlet pipes 603 are outwards expanded under the elastic force of the first elastic element 606 through reversing the adjusting nut 901, the control ring 902 is pulled to move downwards along with the adjusting nut 901, the liquid outlet pipes 603 of the circumferential array can adapt to culture dishes with different diameters, and the liquid outlet pipes 603 can be close to the inner wall edge of the culture dishes by driving a gear 502 to control the moving ring 5 to move downwards, so that culture oil is injected along the inner wall edge of the culture dishes, and impact on embryos is reduced.
Example 3:
referring to fig. 1-9, according to embodiment 1, a placement groove 101 is formed in the support base 1, a clamping assembly 3 is disposed in the placement groove 101, the clamping assembly 3 includes a second elastic element 302 and a plurality of telescopic rods 303 arrayed along the circumference of the sidewall of the placement groove 101, one end of each telescopic rod 303 is fixedly connected with the sidewall of the placement groove 101, the other end is provided with a clamping block 301, and the telescopic rods 303 are controlled to stretch through the second elastic element 302;
in the embodiment, the support base 1 is provided with the placing groove 101, the placing groove 101 is propped against the clamping blocks 301 arranged on the inner circumference array of the placing groove 101 through the second elastic elements 302 of the clamping component 3 to contact with the outer wall of the culture dish in a circle center shrinkage motion, the culture dish is clamped and fixed at the center of the placing groove, the filling head 6 is aligned with the culture dish, the manual calibration is reduced, the filling efficiency is improved, the problems that in the prior art (CN 218666100U), the culture dishes are placed on a conveyor one by one for conveying, the filling component is aligned, the alignment process consumes time, the filling component only can fill one culture dish at a time, and the filling efficiency is low are solved;
in this embodiment, there are at least three telescopic rods 303 arrayed along the circumference of the sidewall of the placement groove 101, and the clamping block 301 has an L-shaped structure, and an anti-slip silica gel layer is disposed on the surface of the clamping block 301 for anti-slip treatment.
The preferred embodiments of the utility model disclosed above are intended only to assist in the explanation of the utility model. The preferred embodiments are not exhaustive or to limit the utility model to the precise form disclosed. Obviously, many modifications and variations are possible in light of the above teaching. The embodiments were chosen and described in order to best explain the principles of the utility model and the practical application, to thereby enable others skilled in the art to best understand and utilize the utility model. The utility model is limited only by the claims and the full scope and equivalents thereof.
Claims (5)
1. The auxiliary liquid feeding device for embryo culture comprises a fixed base, a supporting base and a filling part, and is characterized in that the supporting base is provided with a supporting column, a movable ring is sleeved on the supporting column in a sliding manner, the filling part is slidably mounted on the supporting column through a circumferential array of the movable ring, the filling part comprises a supporting arm and a filling head, an adjusting nut is connected onto the supporting arm in a threaded manner, a control ring is movably sleeved on the adjusting nut, the upper end of the control ring is abutted to the lower end of the adjusting nut, the filling head comprises a control rope, a mounting plate and a liquid outlet pipe, one end of the supporting arm is connected with the movable ring, one end of the supporting arm is connected with the mounting plate, a plurality of sliding grooves are formed in the mounting plate along the circumference of a radius, one end of the liquid outlet pipe is slidably mounted in the sliding grooves through a sliding manner, one end of the control rope is connected with the control ring in a sliding manner through a through hole in the mounting plate, one end of the control rope is driven to slide up and down by rotating the adjusting nut, the control rope is driven to pull the liquid outlet pipe to slide, and the liquid outlet pipe is controlled in an auxiliary manner through a first elastic element arranged in the sliding groove;
the support base is provided with a placing groove, a clamping assembly is arranged in the placing groove, the clamping assembly comprises a second elastic element and a plurality of telescopic rods which are arrayed along the circumference of the side wall of the placing groove, one end of each telescopic rod is fixedly connected with the side wall of the placing groove, the other end of each telescopic rod is provided with a clamping block, and the telescopic rods are controlled to stretch out and draw back through the second elastic element.
2. The embryo culture auxiliary liquid feeding device according to claim 1, wherein the liquid feeding bin is arranged on the supporting arm, the liquid suction pump is arranged on the liquid feeding bin, and the liquid suction pump is connected with the liquid outlet pipe on the mounting plate through the arrangement of the guide pipe.
3. The embryo culture auxiliary liquid feeding device according to claim 1, wherein the support column is provided with a rack, the movable ring is provided with a motor and a gear meshed with the rack, and the motor drives the gear to rotate so as to control the movable ring to slide on the support column.
4. The embryo culture auxiliary liquid feeding device according to claim 1, wherein the stationary base is rotatably mounted below the support base.
5. The auxiliary liquid feeding device for embryo culture according to claim 1, wherein the lower outer edge of the adjusting nut is of a laterally convex annular structure, and the upper inner edge of the control ring is of an inwardly convex annular structure.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202322370245.0U CN220724202U (en) | 2023-09-01 | 2023-09-01 | Auxiliary liquid feeding device for embryo culture |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202322370245.0U CN220724202U (en) | 2023-09-01 | 2023-09-01 | Auxiliary liquid feeding device for embryo culture |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN220724202U true CN220724202U (en) | 2024-04-05 |
Family
ID=90485062
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202322370245.0U Active CN220724202U (en) | 2023-09-01 | 2023-09-01 | Auxiliary liquid feeding device for embryo culture |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN220724202U (en) |
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2023
- 2023-09-01 CN CN202322370245.0U patent/CN220724202U/en active Active
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