CN220643057U - Double-headed nucleic acid extractor - Google Patents
Double-headed nucleic acid extractor Download PDFInfo
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- CN220643057U CN220643057U CN202322046628.2U CN202322046628U CN220643057U CN 220643057 U CN220643057 U CN 220643057U CN 202322046628 U CN202322046628 U CN 202322046628U CN 220643057 U CN220643057 U CN 220643057U
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- rod sleeve
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- 150000007523 nucleic acids Chemical class 0.000 title claims abstract description 27
- 102000039446 nucleic acids Human genes 0.000 title claims abstract description 27
- 108020004707 nucleic acids Proteins 0.000 title claims abstract description 27
- 238000009434 installation Methods 0.000 claims description 28
- 238000000605 extraction Methods 0.000 abstract description 13
- 239000003153 chemical reaction reagent Substances 0.000 abstract description 12
- 238000001514 detection method Methods 0.000 abstract description 3
- 238000000034 method Methods 0.000 description 6
- 230000000712 assembly Effects 0.000 description 2
- 238000000429 assembly Methods 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 210000001503 joint Anatomy 0.000 description 1
- 239000011148 porous material Substances 0.000 description 1
- 238000000746 purification Methods 0.000 description 1
- 238000005070 sampling Methods 0.000 description 1
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- Apparatus Associated With Microorganisms And Enzymes (AREA)
Abstract
The utility model belongs to the technical field of detection instruments, and provides a double-end nucleic acid extraction instrument, wherein a plurality of groups of positioning seats are arranged in a rotary table, and the positioning seats are circumferentially distributed on the rotary table; the magnetic rod positioning device comprises a turntable, a magnetic rod sleeve frame, a magnetic rod rack and two groups of positioning seats, wherein the turntable is arranged on one side of the turntable, the magnetic rod rack and the magnetic rod sleeve frame are all arranged on the frame, the magnetic rod rack is located above the magnetic rod sleeve frame, two groups of first mounting portions are arranged on the magnetic rod rack, two groups of second mounting portions are arranged on the magnetic rod sleeve frame, one group of first mounting portions corresponds to one group of second mounting portions, and the two groups of first mounting portions and the two groups of second mounting portions are the same as the adjacent two groups of positioning seats in distance. According to the utility model, two groups of mounting parts are respectively arranged on the original magnetic rack and the original magnetic bar sleeve rack, so that two groups of magnetic bars and two groups of magnetic bar sleeves can be simultaneously mounted, and two groups of reagents can be extracted each time, so that more samples are extracted, and the extraction efficiency is greatly improved.
Description
Technical Field
The utility model belongs to the technical field of detection instruments, and particularly relates to a double-headed nucleic acid extractor.
Background
Nucleic acid extractor, which is an instrument for automatically completing the extraction of sample nucleic acid by using matched nucleic acid extracting reagent, is divided into two types: one type is large automated, commonly referred to as an automated liquid workstation; the other type is a small automatic nucleic acid extractor, and the extraction and purification process is automatically completed by using the packaged matched reagent. The large-scale automatic liquid workstation is suitable for extracting thousands of specimens of the same type at a time because of high equipment cost and high operation cost, so that the application is really less. And the small-sized automatic instrument has low instrument and equipment and operation cost, and is convenient to operate and widely applied.
The present Chinese patent CN107974394A discloses a nucleic acid extraction instrument, which comprises a machine body, a magnetic rack, a magnetic rod sleeve frame, a magnetic rod sleeve, a drip baffle, a deep pore plate, a positioning seat, a rotary table and a control panel, wherein the magnetic rack and the magnetic rod sleeve frame are stable in up-and-down movement through double tracks, shaking can not occur, and the accuracy of a long-time position can be ensured by one-time calibration. The magnetic rack and the magnetic rod sleeve rack are in a double mode, and different modes can be used according to the size of the sample adding volume. However, this solution only provides a working part for working, and cannot improve the working efficiency in a limited space.
Disclosure of Invention
In order to overcome the problems in the prior art, the utility model aims to provide a double-headed nucleic acid extractor.
The technical scheme adopted for solving the technical problems is as follows: a duplex nucleic acid extractor comprising: the magnetic rod positioning device comprises a frame, a magnetic rod sleeve frame, a magnetic rod sleeve, a turntable and a positioning seat; the positioning seats are provided with a plurality of groups, and the plurality of groups of positioning seats are circumferentially distributed on the turntable; the magnetic rod sleeve rack is arranged on the magnetic rod sleeve rack, and the magnetic rod sleeve rack is arranged on the magnetic rod sleeve rack; the magnetic bar sleeve frame is characterized in that two groups of first installation parts are arranged on the magnetic bar frame, two groups of second installation parts are arranged on the magnetic bar sleeve frame, the two groups of first installation parts and the two groups of second installation parts are in one-to-one correspondence in the vertical direction, and the two groups of first installation parts and the two groups of second installation parts are all arranged above the path of the travelling of the positioning seat, and when the turntable stops rotating, the positions of the two groups of second installation parts in the vertical direction are in one-to-one correspondence with the positions of two groups of adjacent positioning seats in the vertical direction.
The method is characterized in that when nucleic acid extraction and detection are needed, a reagent tube is pre-installed in a positioning seat, a magnetic rod and a magnetic rod sleeve are installed in a corresponding magnetic frame and the magnetic rod sleeve frame, equipment is started, a turntable drives the positioning seat above to rotate, when the positioning seat rotates below the magnetic rod sleeve frame, rotation can be stopped, then the rack can control the magnetic frame and the magnetic rod sleeve frame to descend, so that the magnetic rod and the magnetic rod sleeve are inserted into the reagent tube for nucleic acid extraction, after the extraction is finished, the rack can control the magnetic frame and the magnetic rod sleeve frame to lift up, the turntable rotates again for next round of extraction, and two groups of first installation parts are arranged on the magnetic rod sleeve frame, so that two groups of magnetic rods and magnetic rod sleeves can be installed, two groups of adjacent reagent tubes can be extracted simultaneously in the process of rotation, and the turntable is arranged at intervals of every two groups of positioning seats.
Preferably, the magnetic rack and the magnetic bar sleeve rack are fan-shaped, and the long sides of the magnetic rack and the magnetic bar sleeve rack are connected with the rack, and the two groups of the first installation parts and the second installation parts are equally arranged on two sides of the connection part of the rack.
Preferably, a slot is formed in one side of the second installation portion, and the support plate of the magnetic rod sleeve frame is connected with the slot in a matched mode.
Preferably, a notch is arranged at the opening of the slot, and when the magnetic rod sleeve is inserted into the slot, the part of the magnetic rod sleeve, which is positioned at the notch, is leaked outwards.
Preferably, a plurality of groups of through holes are formed in the side, facing the first mounting portion, of the second mounting portion, and the position of each through hole corresponds to the mounting portion of the magnetic rod.
Preferably, the rack comprises a support, a connecting block and a driving assembly, the driving assembly comprises a driving wheel, a driven wheel, a track and a driving motor, the support is vertically installed on one side of the turntable, the track is arranged along the direction of the support, the driving wheel and the driven wheel are respectively arranged at two ends of the track, the driving end of the driving motor is matched with the driving wheel, and the magnetic frame and the magnetic bar sleeve frame are matched and connected with the track through the connecting block.
Preferably, the connecting blocks and the driving assemblies are respectively provided with two groups, and the two groups of connecting blocks and the driving assemblies are respectively connected with the magnetic frame and the magnetic rod sleeve frame in a matched mode.
Preferably, a clamping seat is arranged on the turntable, and the positioning seat is buckled in the clamping seat.
Compared with the prior art, the utility model has the beneficial effects that:
1. according to the utility model, two groups of mounting parts are respectively arranged on the original magnetic rack and the magnetic rod sleeve rack, so that two groups of magnetic rods and magnetic rod sleeves can be simultaneously mounted, and along with the rotation of the turntable, two groups of reagent tubes can be extracted and detected each time, so that more samples are extracted, and the extraction efficiency is greatly improved.
Drawings
In order to more clearly illustrate the technical solutions of the embodiments of the present utility model, the drawings required for the description of the embodiments will be briefly described below, and it is obvious that the drawings in the following description are some embodiments of the present utility model, and other drawings may be obtained according to these drawings without inventive effort for a person skilled in the art.
FIG. 1 is a schematic diagram showing the loading state of the double-headed nucleic acid extractor;
FIG. 2 is a partially enlarged view of the double-ended nucleic acid extractor of FIG. 1 in a loaded state;
FIG. 3 is a schematic diagram of the double-headed nucleic acid extractor in a loaded empty state;
FIG. 4 is a side view of the double-ended nucleic acid extractor;
FIG. 5 is a partial cross-sectional view of the housing of FIG. 4;
1. a frame; 10. a bracket; 11. a connecting block; 12. a drive assembly; 120. a driving wheel; 121. driven wheel; 122. a track; 123. a driving motor; 2. a magnetic frame; 20. a first mounting portion; 3. a magnetic rod; 4. a magnetic rod sleeve frame; 40. a second mounting portion; 41. a slot; 42. a notch; 43. a through hole; 5. a magnetic rod sleeve; 6. a turntable; 60. a clamping seat; 7. and a positioning seat.
Detailed Description
In order that the above-recited objects, features and advantages of the present utility model will be more clearly understood, a more particular description of the utility model will be rendered by reference to the appended drawings and appended detailed description. In addition, embodiments of the present application and features of the embodiments may be combined with each other without conflict. In the following description, numerous specific details are set forth in order to provide a thorough understanding of the present utility model, and the described embodiments are merely some, rather than all, embodiments of the present utility model. All other embodiments, which can be made by those skilled in the art based on the embodiments of the present utility model without making any inventive effort, are intended to fall within the scope of the present utility model.
Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this utility model belongs. The terminology used herein in the description of the utility model is for the purpose of describing particular embodiments only and is not intended to be limiting of the utility model.
As shown in fig. 1-5, the utility model specifically discloses a double-end nucleic acid extractor, which comprises a frame 1, a magnetic frame 2, a magnetic rod 3, a magnetic rod sleeve frame 4, a magnetic rod sleeve 5, a rotary table 6 and a positioning seat 7, wherein the rotary table 6 is arranged in parallel with a horizontal plane, a motor is arranged on a bottom plate of the rotary table 6, the motor can drive the rotary table 6 to integrally rotate, a plurality of groups of positioning seats 7 are circumferentially distributed at the edge of the upward side of the rotary table 6, the intervals between every two adjacent groups of positioning seats 7 are the same, the positioning seats 7 are used for installing reagent tubes, and when the rotary table 6 rotates, each group of positioning seats 7 rotate along the edge of the rotary table 6, so that the positions of the positioning seats 7 are changed, and the conversion between stations is realized. The machine frame 1 is installed on one side of the turntable 6, the magnetic frame 2 and the magnetic rod sleeve frame 4 are sequentially installed on the machine frame 1 from top to bottom, the magnetic frame 2 and the magnetic rod sleeve frame 4 are located above the movement track of the positioning seat 7, the machine frame 1 is used for driving the magnetic frame 2 and the magnetic rod sleeve frame 4 to move up and down, and therefore the magnetic rods 3 and the magnetic rod sleeve 5 installed on the magnetic frame 2 and the magnetic rod sleeve frame 4 can be inserted into a reagent tube, and the sampling operation is completed.
It should be noted that, in this solution, the magnetic frame 2 and the magnetic rod sleeve frame 4 are provided with two working parts, the two first working parts are disposed on two sides of the magnetic frame 2 with the connection between the magnetic frame 2 and the frame 1 as a central line, and the two second working parts, i.e. the connection between the magnetic rod sleeve frame 4 and the frame 1, are disposed on two sides of the magnetic rod sleeve frame 4 with the central line. The positions of the two first working parts and the two second working parts are aligned up and down, so that the magnetic rod 3 installed in the first installation part 20 can be smoothly inserted into the magnetic rod sleeve 5 installed in the second working part in the descending process, and the matching of the magnetic rod 3 and the magnetic rod sleeve 5 is realized. Meanwhile, since the magnetic rod 3 and the magnetic rod sleeve 5 need to be inserted into the reagent tube below to be matched with the reagent tube, the positions of the two second fixing parts need to correspond to the positions of the two groups of adjacent positioning seats 7 in the extraction process, and therefore, the magnetic frame 2 and the magnetic rod sleeve frame 4 need to be set into a fan shape, the circle center position of the fan shape is overlapped with the circle center position of the turntable 6, a concentric circle structure is formed between the magnetic rod and the magnetic rod sleeve frame, and the first fixing part and the second fixing part are ensured to be always positioned above the moving track of the positioning seats 7. Meanwhile, the long sides of the magnetic frame 2 and the magnetic bar sleeve frame 4 are connected with the frame 1, so that the magnetic bar sleeve frame is fixedly connected with the frame 1.
In addition, it is necessary to explain the connection relationship of the magnetic frame 2, the bar magnet holder 4 and the frame 1 in particular, wherein, as shown in fig. 4 to 5, the frame 1 includes a bracket 10, a connection block 11 and a driving assembly 12, wherein the bracket 10 is vertically installed at one side of the turntable 6, the driving assembly 12 is disposed along the length direction of the bracket 10, and the magnetic frame 2 and the bar magnet holder 4 are connected with the driving assembly 12 through the connection block, and the magnetic frame 2 and the bar magnet holder 4 are moved up and down by the driving assembly 12. More specifically, the driving assembly 12 includes a driving wheel 120, a driven wheel 121, a track 122, and a driving motor 123, wherein the driving motor 123 is installed at the bottom of the support 10, the driving wheel 120 is installed at the driving end of the driving motor 123, the driven wheel 121 is installed at the top of the support 10, the track 122 is sleeved on the periphery of the driving wheel 120 and the driven wheel 121, the clamping groove on the connecting block 11 is clamped on the track 122, and the track 122 is clamped by inserting a screw into the clamping groove from the outer side of the connecting block 11, so that the connecting block 11 can be stably fixed on the track 122. In the working process, the driving motor 123 is started to drive the driving wheel 120 to rotate, the driving wheel 120 is meshed with the crawler belt 122, so that the crawler belt 122 rotates, the magnetic frame 2 and the magnetic rod sleeve frame 4 are driven by the crawler belt 122 to move, and the driving motor 123 controls forward rotation and reverse rotation, so that the magnetic frame 2 and the magnetic rod sleeve frame 4 move up and down. In order to ensure the moving stability of the magnetic frame 2 and the magnetic rod sleeve frame 4, a guide rod which is vertically arranged is further arranged, and the periphery of the guide rod is sleeved with the connecting rod to move along the guide rod, so that the whole magnetic frame 2 and the magnetic rod sleeve frame 4 are smoother and more stable in the moving process.
Meanwhile, in the extraction process, the magnetic rod 3 is required to be inserted into the magnetic rod sleeve 5, then the magnetic rod 3 and the magnetic rod sleeve 5 are inserted into the reagent tube together, so that the magnetic rod 3 and the magnetic rod sleeve 5 are required to be moved independently, two groups of connecting blocks 11 and driving components 12 are required to be arranged, the two groups of connecting blocks 11 and the driving components 12 are respectively connected with the magnetic frame 2 and the magnetic rod sleeve frame 4 in a matched manner, and the magnetic rod 3 and the magnetic rod sleeve 5 can be driven to move up and down independently, so that the matching of the magnetic rod 3 and the magnetic rod sleeve 5 is more consistent.
Further, as shown in fig. 2, a transverse slot 41 is provided on one side of the second installation portion 40 facing outward, the size and shape of the slot 41 corresponds to the support plate of the magnetic rod sleeve 5, the magnetic rod sleeve 5 is quickly assembled in a butt joint fit with the second installation portion 40 by inserting the slot 41, and after the magnetic rod sleeve 5 is assembled, the support plate of the magnetic rod sleeve 5 is clamped by tightening the screw on the outer side of the slot 41, so that the magnetic rod sleeve 5 is fastened. When the bar magnet cover 5 needs to be replaced, the bar magnet cover 5 can be taken out of the slot 41 only by loosening the screw for fastening, and then a new bar magnet cover 5 is inserted.
Further, in order to facilitate the taking out of the magnetic rod sleeve 5, a notch 42 is arranged at the opening of the slot 41, when the magnetic rod sleeve 5 is inserted into the slot 41, the part of the magnetic rod sleeve 5 positioned at the notch 42 leaks outwards, and in the process of taking out the magnetic rod sleeve 5, the slot 41 can be taken out by grabbing the leaking part, so that the situation that the magnetic rod sleeve 5 needs to be buckled out of the slot 41 is avoided.
Further, be equipped with cassette 60 on the carousel 6, positioning seat 7 lock is in the cassette 60 to realized the quick cooperation installation of positioning seat 7, thereby can change positioning seat 7 according to the difference of bar magnet cover 5, improved the practicality of this double-end nucleic acid extraction appearance.
The present utility model is not limited to the preferred embodiments, and any modifications, equivalent variations and modifications made to the above embodiments according to the technical principles of the present utility model are within the scope of the technical proposal of the present utility model.
Claims (8)
1. A duplex nucleic acid extractor, comprising:
the magnetic rod positioning device comprises a frame, a magnetic rod sleeve frame, a magnetic rod sleeve, a turntable and a positioning seat;
the positioning seats are provided with a plurality of groups, and the plurality of groups of positioning seats are circumferentially distributed on the turntable;
the magnetic rod sleeve rack is arranged on the magnetic rod sleeve rack, and the magnetic rod sleeve rack is arranged on the magnetic rod sleeve rack;
the magnetic bar sleeve frame is provided with two groups of first installation parts, the magnetic bar sleeve frame is provided with two groups of second installation parts, the two groups of first installation parts and the two groups of second installation parts are in one-to-one correspondence in the vertical direction, and the two groups of first installation parts and the two groups of second installation parts are arranged above the travelling path of the positioning seat; when the turntable stops rotating, the positions of the two groups of second installation parts in the vertical direction correspond to the positions of two groups of adjacent positioning seats in the vertical direction one by one.
2. The double-headed nucleic acid extractor according to claim 1, wherein,
the magnetic force frame with the bar magnet cover frame all is fan-shaped, just the magnetic force frame with the long limit of bar magnet cover frame all with the frame is connected, two sets of first installation department and both the second installation department equally divide to be established with the both sides of frame junction.
3. The double-headed nucleic acid extractor according to claim 1, wherein,
one side of the second installation part is provided with a slot, and the support plate of the magnetic rod sleeve frame is connected with the slot in a matching way.
4. The double-ended nucleic acid extractor according to claim 3, wherein,
the opening part of the slot is provided with a notch, and when the magnetic rod sleeve is inserted into the slot, the part of the magnetic rod sleeve, which is positioned at the notch, is leaked outwards.
5. The double-headed nucleic acid extractor according to claim 1, wherein,
and a plurality of groups of through holes are formed in one side of the second installation part, facing the first installation part, of the whole row and the whole column, and the position of each through hole corresponds to the installation part of the magnetic rod.
6. The double-headed nucleic acid extractor according to claim 1, wherein,
the frame comprises a bracket, a connecting block and a driving component,
the driving component comprises a driving wheel, a driven wheel, a crawler belt and a driving motor,
the support is vertically installed on one side of the turntable, the crawler belt is arranged along the direction of the support, the driving wheel and the driven wheel are respectively arranged at two ends of the crawler belt, the driving end of the driving motor is matched with the driving wheel, and the magnetic force frame and the magnetic bar sleeve frame are matched and connected with the crawler belt through the connecting blocks.
7. The double-ended nucleic acid extractor according to claim 6, wherein,
the connecting block and the driving component are respectively provided with two groups, and the two groups of connecting blocks and the driving component are respectively connected with the magnetic frame and the magnetic rod sleeve frame in a matched mode.
8. The double-headed nucleic acid extractor according to claim 1, wherein,
the turntable is provided with a clamping seat, and the positioning seat is buckled in the clamping seat.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202322046628.2U CN220643057U (en) | 2023-07-31 | 2023-07-31 | Double-headed nucleic acid extractor |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202322046628.2U CN220643057U (en) | 2023-07-31 | 2023-07-31 | Double-headed nucleic acid extractor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN220643057U true CN220643057U (en) | 2024-03-22 |
Family
ID=90294985
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202322046628.2U Active CN220643057U (en) | 2023-07-31 | 2023-07-31 | Double-headed nucleic acid extractor |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN220643057U (en) |
-
2023
- 2023-07-31 CN CN202322046628.2U patent/CN220643057U/en active Active
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