CN220603487U - Cell detector - Google Patents

Cell detector Download PDF

Info

Publication number
CN220603487U
CN220603487U CN202322151494.0U CN202322151494U CN220603487U CN 220603487 U CN220603487 U CN 220603487U CN 202322151494 U CN202322151494 U CN 202322151494U CN 220603487 U CN220603487 U CN 220603487U
Authority
CN
China
Prior art keywords
sample
cell
rotary
cell detector
moving member
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN202322151494.0U
Other languages
Chinese (zh)
Inventor
吴旭东
帅宇
吴礼杰
吴英杰
吴少文
王鑫
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Suzhou Shuangcai Biotechnology Co ltd
Original Assignee
Suzhou Shuangcai Biotechnology Co ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Suzhou Shuangcai Biotechnology Co ltd filed Critical Suzhou Shuangcai Biotechnology Co ltd
Priority to CN202322151494.0U priority Critical patent/CN220603487U/en
Application granted granted Critical
Publication of CN220603487U publication Critical patent/CN220603487U/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Landscapes

  • Automatic Analysis And Handling Materials Therefor (AREA)

Abstract

The utility model discloses a cell detector, which comprises: the detection module comprises a plurality of cell detectors, each cell detector is provided with a sample adding port for adding samples, the rotary sample adding module comprises a rotary table, a first rotary motor and a plurality of sample containers arranged on the rotary table, the rotary table is connected with the first rotary motor, the first rotary motor is used for driving the rotary table to rotate so that the sample containers can move to a manual sample adding position and an automatic sample adding position, the liquid moving module comprises a moving component and a liquid moving device loaded on the moving component, and the liquid moving device can move to the sample adding port of the automatic sample adding position and the cell detector under the driving of the moving component. According to the cell detector provided by the utility model, by adopting a design that a plurality of detectors are combined with a rotary sample loading module to work in parallel, the detection and analysis of a plurality of cell samples with high speed, high precision and high automation are realized, so that the efficiency bottleneck problem existing in the traditional single detector design is solved.

Description

Cell detector
Technical Field
The utility model relates to the technical field of cell detection, in particular to a cell detector.
Background
The cell detector is a key device widely applied in the fields of biomedical research, clinical diagnosis, biotechnology and the like, and has the main function of realizing high-precision and high-efficiency detection and analysis of cell samples. With the continuous progress of scientific research and medical fields, the requirements on the detection efficiency, accuracy and automation degree of the cell detector are higher and higher.
In conventional cell detection techniques, most cell detectors are based on a single detector design. The main advantage of this design is simplicity and reliability, facilitating user operation and maintenance. However, this also brings a significant limitation in that when multiple cell samples are to be tested, these samples can only be loaded sequentially for testing, and parallel processing cannot be achieved. This clearly increases the detection time, and presents a significant efficiency bottleneck for scenarios requiring rapid acquisition of results, such as emergency diagnostics or large-scale sample analysis.
For modern scientific laboratories, medical diagnostic centers, and biotechnology companies, the sample size is often large-scale and often requires detection results in a short period of time. For example, when a disease is prevalent or an epidemic outbreak, a large number of samples need to be detected and analyzed in a minimum amount of time, and conventional single detector designs are not able to meet this high efficiency requirement.
In addition, along with the development of personalized medicine and accurate medicine, the high-throughput and high-efficiency requirements on the cell detector are more urgent. The single detector design allows only one sample to be processed at a time, which significantly reduces the overall operating efficiency of the detector, especially when multiple parameters need to be analyzed.
Therefore, in view of the above-mentioned technical problems, it is necessary to provide a new cell detector.
Disclosure of Invention
The utility model aims to provide a cell detector which can improve cell detection efficiency.
In order to achieve the above purpose, the technical scheme provided by the utility model is as follows:
a cell detector, comprising:
the detection module comprises a plurality of cell detectors, wherein each cell detector is provided with a sample adding port for adding a sample;
the rotary sample loading module comprises a rotary table, a first rotary motor and a plurality of sample containers arranged on the rotary table, wherein the rotary table is connected with the first rotary motor, and the first rotary motor is used for driving the rotary table to rotate so as to enable the sample containers to move to a manual sample loading position and an automatic sample sampling position;
the pipetting module comprises a transferring assembly and a pipetting device loaded on the transferring assembly, and the pipetting device can be driven by the transferring assembly to move to the automatic sampling position and the sampling port of the cell detector.
In one or more embodiments, the cell detector comprises a housing, a detection unit and a flow channel, wherein the sample adding port is arranged on the housing, the detection unit is accommodated in the housing, and the flow channel is communicated with the sample adding port and the detection unit.
In one or more embodiments, a plurality of the cell detectors are arranged in sequence, and the plurality of the cell detectors are arranged within a movement range of the transfer assembly.
In one or more embodiments, a plurality of clamping pieces with clamping openings are sequentially arranged at intervals along the circumferential direction on the periphery of the rotary disc, the sample container is clamped on the clamping openings, and the sample container can be taken off from the clamping openings under the action of external force.
In one or more embodiments, the manual loading position is provided with a sensor, and when the turntable drives the clamping piece to move to the manual loading position, a user can clamp the sample container on the clamping piece so as to trigger the sensor to generate an electric signal.
In one or more embodiments, the rotary sample loading module further comprises a cover body, wherein the cover body is covered above the rotary disc and the sample container, and a sample loading port corresponding to the automatic sampling position is formed in the cover body.
In one or more embodiments, the transfer assembly includes an X-axis moving member, a Y-axis moving member, and a Z-axis moving member, the Y-axis moving member is mounted on the X-axis moving member, the Z-axis moving member is mounted on the Y-axis moving member, the pipette is mounted on the Z-axis moving member, the X-axis moving member is configured to drive the pipette to move along an X-axis direction, the Y-axis moving member is configured to drive the pipette to move along a Y-axis direction, and the Z-axis moving member is configured to drive the pipette to move along a Z-axis direction, so that a moving range of the pipette can cover the detection module and the rotary loading module.
In one or more embodiments, the cell detector further comprises a recovery module, the recovery module comprises a waste liquid needle, a support rod and a first linear motor, one end of the support rod is fixed on an output shaft of the first linear motor, the waste liquid needle is fixed on the other end of the support rod, and the waste liquid needle can be driven by the first linear motor and the second rotary motor to move to the position of the sample container so as to absorb waste liquid in the sample container.
In one or more embodiments, the recycling module further comprises a push rod, a second linear motor, a slide way and a collecting box, wherein the push rod is installed on an output shaft of the second linear motor, the push rod can push out a sample container installed on the rotary table under the driving of the second linear motor, an inlet end of the slide way is arranged adjacent to the periphery of the rotary table, and an outlet end of the slide way is arranged corresponding to the collecting box, so that the sample container pushed out by the push rod can slide into the collecting box along the slide way.
In one or more embodiments, the cell detector further comprises a monitoring module, the monitoring module comprises a camera, a light source and a display, the camera and the light source are arranged corresponding to the rotary sample loading module and a consumable placement area, the display is connected with the camera to display images shot by the camera, and the consumable placement area is used for placing a pipette tip and a staining solution container.
Compared with the prior art, the cell detector provided by the utility model realizes high-speed, high-precision and high-automation detection and analysis of a plurality of cell samples by adopting a design that a plurality of detectors are combined with a rotary sample loading module to work in parallel, so that the efficiency bottleneck problem existing in the traditional single detector design is solved; meanwhile, the rotary sample loading module and the pipetting module are adopted to realize rapid switching and positioning, accurate sampling and sample loading of a plurality of cell samples, so that the degree of automation and convenience of the cell detector are improved.
Drawings
FIG. 1 is a schematic perspective view of a cell detector according to an embodiment of the present utility model;
FIG. 2 is a schematic perspective view of a cell detector of the cell detector of FIG. 1;
FIG. 3 is an exploded view of the rotary loading module of the cytometer of FIG. 1;
FIG. 4 is a schematic perspective view of a pipetting module in the cytometer of FIG. 1;
FIG. 5 is a schematic perspective view of the recycling module of the cell analyzer of FIG. 1;
FIG. 6 is a schematic perspective view of the recycling module of the cytometer of FIG. 1 at another view angle.
The main reference numerals illustrate:
the device comprises a 1-detection module, a 11-cell detector, a 111-sample loading port, a 112-shell, a 113-detection unit, a 114-runner, a 2-rotary sample loading module, a 21-turntable, a 22-first rotary motor, a 23-sample container, a 24-clamping piece, a 241-clamping port, a 25-sensor, a 26-cover, a 261-sample loading port, a 3-pipetting module, a 31-transferring module, a 311-X-axis moving piece, a 312-Y-axis moving piece, a 313-Z-axis moving piece, a 32-pipetting device, a 4-recovery module, a 41-waste liquid needle, a 42-supporting rod, a 43-first linear motor, a 45-supporting rod, a 46-second linear motor, a 47-slideway, a 48-collecting box, a 5-monitoring module, a 51-camera and a 52-display.
Detailed Description
The following detailed description of embodiments of the utility model is, therefore, to be taken in conjunction with the accompanying drawings, and it is to be understood that the scope of the utility model is not limited to the specific embodiments.
Throughout the specification and claims, unless explicitly stated otherwise, the term "comprise" or variations thereof such as "comprises" or "comprising", etc. will be understood to include the stated element or component without excluding other elements or other components.
In the field of cell detection technology, the efficiency and accuracy of the detector are always the focus of research and improvement. With the continuous increase of the demands for cell detection in the fields of scientific research, medical treatment, biotechnology and the like, the conventional cell detector encounters obvious challenges: when a large number of samples need to be detected rapidly and accurately, a single cell detector is proved to catch the forepart and break the elbow, and the parallel and efficient detection requirements cannot be met.
Based on the analysis of the problems, the utility model provides a new implementation idea: the traditional single detector design is upgraded to a multi-detector modular system, and each sample is ensured to be accurately and rapidly sent to the corresponding detector for detection by an automatic sample processing mechanism.
The core of the realization thought is that firstly, the parallelism of detection is improved through modularized design, so that the processing efficiency is remarkably improved; secondly, by utilizing an automatic sample processing mechanism, the sample taking and detecting are completed in a set of system, so that the operation steps are greatly simplified, and the complexity and error rate of manual operation are reduced.
In general, the technical realization thought of the utility model is to fundamentally solve the problem of low efficiency of the traditional cell detector by modularized and automatic design, so that the cell detector can meet the detection requirements of high efficiency and high accuracy in the modern scientific research and medical field.
Referring to fig. 1 to 6, a cell detector according to an embodiment of the utility model includes: the device comprises a detection module 1, a rotary sample loading module 2 and a pipetting module 3. The detection module 1 includes a plurality of cell detectors 11, each cell detector 11 having a sample-adding port 111 for adding a sample. The rotary sample loading module 2 comprises a rotary table 21, a first rotary motor 22 and a plurality of sample containers 23 mounted on the rotary table 21, wherein the rotary table 21 is connected with the first rotary motor 22, and the first rotary motor 22 is used for driving the rotary table 21 to rotate so as to enable the sample containers 23 to move to a manual sample loading position and an automatic sample loading position. The pipetting module 3 includes a transfer unit 31 and a pipetting device 32 mounted on the transfer unit 31, and the pipetting device 32 can be moved to an automatic sampling position and a loading port 111 of the cell detector 11 by driving the transfer unit 31.
Referring to fig. 1 and 2, the detection module 1 includes a plurality of cell detectors 11, and each cell detector 11 has a sample inlet 111 for adding a sample. Each cell detector 11 can be adaptively adjusted and optimized for different cell samples and detection targets, and can be used for comprehensive detection simultaneously or alternately using a variety of principles and methods. For example, the characteristics of cell morphology, number, activity, etc. may be detected using an optical principle, the characteristics of cell resistance, capacitance, conductance, etc. may be detected using an electrical principle, and the characteristics of cell enzyme activity, metabolites, signal molecules, etc. may be detected using a chemical principle. Therefore, the capability and effect of the cell detector in acquiring and processing various and multi-level cell information can be enhanced, and the flexibility and accuracy of the cell detector can be improved. The core detection unit 113 of the cell detector 11 may be a conventional detection unit 113, and is not particularly limited herein.
Referring to fig. 1 and 3, the rotary loading module 2 includes a turntable 21, a first rotary motor 22, and a plurality of sample containers 23 mounted on the turntable 21, wherein the turntable 21 is connected to the first rotary motor 22, and the first rotary motor 22 is used for driving the turntable 21 to rotate so as to move the sample containers 23 to a manual loading position and an automatic sampling position. The rotary sample loading module 2 can realize rapid switching and positioning of a plurality of cell samples, thereby improving the efficiency and the automation degree of the cell detector. The turntable 21 provides stable support and positioning for the sample container 23, ensuring stability of the sample container 23 during sampling. The first rotary motor 22 drives the rotary table 21 to rotate, so that the automatic movement of the sample container 23 is realized, and the sample container 23 can be accurately moved to an automatic sampling position. The sample container 23 stores cell samples, the position of which is synchronized with the rotation of the turntable 21, ensuring that each sample can be sampled.
Referring to fig. 1 and 4, the pipetting module 3 includes a transferring unit 31 and a pipetting device 32 mounted on the transferring unit 31, wherein the pipetting device 32 can be moved to an automatic sampling position and a loading port 111 of the cell detector 11 by driving the transferring unit 31. The transfer assembly 31 drives the movement of the pipetter 32, ensuring that the pipetter 32 can sample from the sample container 23 and accurately move to the loading port 111 of the cell detector 11. The pipettes 32 take and transfer samples, the design of which ensures that the amount of sample taken each time is accurate and consistent, ensuring the accuracy of the test. The pipetting module 3 can accurately sample and load cell samples, thereby ensuring the accuracy and stability of the cell detector.
In an exemplary embodiment, referring to fig. 2, the cell detector 11 includes a housing 112, a detection unit 113, and a flow channel 114, wherein the sample inlet 111 is disposed on the housing 112, the detection unit 113 is accommodated in the housing 112, and the flow channel 114 communicates with the sample inlet 111 and the detection unit 113.
The housing 112 is an external structure of the cell detector 11, and may be used to protect the detection unit 113 from external interference and damage, to provide structural support and protection for the cell detector 11, and to ensure that internal sensitive elements are protected from external influences, such as dust, mechanical impact, etc., thereby ensuring the stability and accuracy of detection. The housing 112 may be made of metal, plastic, glass, etc., and has a certain strength and durability. The shape and size of the housing 112 may be designed to accommodate different installation and use scenarios, depending on the type and requirements of the detector. The loading port 111 on the housing 112 may be tapered, rounded or otherwise shaped to facilitate easy injection, possibly with a gasket or gasket to ensure that fluid does not leak.
The detection unit 113 is a core component of the cell detector 11, and can be used for detection and analysis of cell samples in a variety of principles and methods. The detection unit 113 may include components of a light source 52, a filter, a lens, a photoelectric converter, an electrode, a circuit board, a sensor, a signal processor, and the like. The detection unit 113 may be adaptively adjusted and optimized according to different cell samples and detection targets, for example, cell detection may be performed based on physical or chemical principles such as fluorescence, resistance, capacitance, etc.
The flow channel 114 is a connecting member of the cell detector 11, and can be used to convey a cell sample from the sample application port 111 to the detection unit 113 and discharge the detected sample. The flow channel 114 can be realized in the form of a pipeline, a microfluidic chip and the like, and has certain fluidity and controllability. The flow channels 114 can be adaptively adjusted according to different flow rates and pressures, thereby ensuring uniform distribution and efficient use of the cell sample.
Specifically, the plurality of cell detectors 11 are arranged in order, and the plurality of cell detectors 11 are arranged within the movement range of the transfer unit 31. The plurality of cell detectors 11 are sequentially arranged, that is, the cell detectors 11 are arranged on the same plane or different planes in a certain order and interval, thereby forming a detection array. The design can realize the detection and analysis of a plurality of cell samples at high speed, high precision and high automation, thereby improving the efficiency and the flexibility of the cell detector. The plurality of cell detectors 11 may detect using the same or different principles and methods, thereby improving the accuracy and integrity of the cell detector. The plurality of cell detectors 11 are arranged within the movement range of the transfer unit 31 so that the positions and directions of the cell detectors 11 match the movement track and direction of the transfer unit 31, thereby enabling the pipetter 32 to be moved to the sample loading port 111 of any one cell detector 11 under the driving of the transfer unit 31.
In an exemplary embodiment, referring to fig. 3, a plurality of clamping members 24 having clamping openings 241 are sequentially arranged at intervals along the circumferential direction of the periphery of the turntable 21, the sample container 23 is clamped on the clamping openings 241, and the sample container 23 can be removed from the clamping openings 241 under the action of external force.
The turntable 21 may be made of a strong material such as metal, high strength plastic, etc., the surface of which may be coated with a corrosion resistant coating. The clamping member 24 with the clamping opening 241 refers to a mechanical device capable of fixing and releasing the sample container 23, and can be realized by adopting the principles of springs, magnets, buckles and the like, and has certain elasticity and adjustability. The plurality of holders 24 are sequentially provided at intervals in the circumferential direction on the outer circumference of the turntable 21, thereby forming an annular array of one sample container 23. The design of the nip 241 is required to ensure a moderate clamping force under normal operation, both to secure the sample container 23 and not to cause container breakage. The sample container 23 may be a vial, tube or other shaped container made of glass or plastic, the bottom or side wall of which may have a specific configuration to accommodate the securement of the nip 241.
Specifically, the manual loading position is provided with a sensor 25, and when the turntable 21 drives the clamping piece 24 to move to the manual loading position, a user can clamp the sample container 23 on the clamping opening of the clamping piece 24 to trigger the sensor 25 to generate an electric signal. The sensor 25 may be a photoelectric sensor, a magnetic sensor, a capacitive sensor or other type of proximity sensor. The sensor 25 may be embedded in a fixed base or frame, ensuring its way to the sample container 23. The sensor 25 is provided at the manual loading position so that it is possible to accurately monitor whether the sample container 23 is loaded onto the holder 24. When the sample container 23 is properly loaded onto the holder 24, the sensor 25 can be triggered and generate an electrical signal. This design allows for automatic detection of whether the sample container 23 is properly loaded, thereby ensuring the degree of automation of the cell detector.
It should be noted that the electrical signal refers to an electrical signal generated by the sensor 25, which may be used to indicate whether the sample container 23 is properly loaded onto the holder 24, thereby triggering the corresponding actions and feedback. For example, an electrical signal may be used to control the first rotary motor 22 to rotate, thereby causing the turntable 21 to move the loaded sample container 23 away from the manual loading position and move the gripper 24 of the next unloaded sample container 23 to the manual loading position.
Further, the rotary sample loading module 2 further includes a cover 26, the cover 26 is covered above the turntable 21 and the sample container 23, a sample loading opening 261 corresponding to the manual sample loading position is provided on the cover 26, and when the clamping member 24 moves to the manual sample loading position, the sample loading opening 261 is exposed, so that a user can load and clamp the sample container 23 onto the clamping member 24.
The cover 26 is an additional structure of the rotary loading module 2, and can be used for covering the turntable 21 and the sample container 23, thereby protecting the cell sample from external pollution and interference, and ensuring the detection accuracy. The cover 26 may be made of metal, plastic, glass, etc., and has a certain strength and durability. The shape and size of the cover 26 can be designed according to different turntables 21 and sample containers 23 to accommodate different installation and use scenarios. The loading port 261 is an opening in the cover 26 that may be used to allow the clamp 24 to be exposed from under the cover 26 when moved to the manual loading position, thereby facilitating loading and clamping of the sample container 23 onto the clamp 24 by a user. The loading port 261 can be realized by adopting a shape such as a circle, a square, an ellipse and the like, and has a certain size and position. The shape and size of the loading port 261 can be designed to accommodate different loading requirements based on different sample containers 23 and clamps 24. The loading port 261 may be positioned to correspond to the sensor 25.
In an exemplary embodiment, referring to fig. 4, the transfer assembly 31 includes an X-axis moving member 311, a Y-axis moving member 312, and a Z-axis moving member 313, the Y-axis moving member 312 is mounted on the X-axis moving member 311, the Z-axis moving member 313 is mounted on the Y-axis moving member 312, the pipette 32 is mounted on the Z-axis moving member 313, the X-axis moving member 311 is used for driving the pipette 32 to move along the X-axis direction, the Y-axis moving member 312 is used for driving the pipette 32 to move along the Y-axis direction, and the Z-axis moving member 313 is used for driving the pipette 32 to move along the Z-axis direction, so that the moving range of the pipette 32 can cover the detection module 1 and the rotary sample assembly 2.
The X-axis moving member 311, the Y-axis moving member 312, and the Z-axis moving member 313 refer to mechanical devices capable of realizing parallel movement in a three-dimensional space, and can be realized by adopting the principles of a slide rail, a screw rod, a rack, a belt, and the like, and have certain speed and precision. The X-axis moving member 311, the Y-axis moving member 312, and the Z-axis moving member 313 are sequentially installed in a vertical relationship, thereby forming a three-degree-of-freedom motion platform. This design allows for precise control and adjustment of the pipette 32, thereby ensuring the accuracy and stability of the cell detector. The detection module 1 and the rotary loading module 2 are arranged in the working range of the transfer assembly 31, so that the pipettor 32 can be effectively docked with the detection module 1 and the rotary loading module 2.
The pipette 32 is a device capable of sampling and adding a cell sample, and can be realized by adopting the principles of a syringe, a suction tube, a pump and the like, and has certain capacity and adjustability. The pipettor 32 is mounted on the Z-axis moving member 313 so as to be connected with a three-degree-of-freedom moving platform, so that the pipettor 32 can perform sampling or sample adding operations at any position in a three-dimensional space.
In an exemplary embodiment, referring to fig. 1, 5 and 6, the cell detector further includes a recovery module 4, where the recovery module 4 includes a waste needle 41, a support rod 42, and a first linear motor 43, one end of the support rod 42 is fixed on an output shaft of the first linear motor 43, the waste needle 41 is fixed on the other end of the support rod 42, and the waste needle 41 can be moved to the sample container 23 under the driving of the first linear motor 43 to suck the waste liquid in the sample container 23. The waste liquid needle 41 may be connected to a liquid pump through a hose, a negative pressure is formed in the waste liquid needle 41 by the liquid pump to suck the waste liquid in the sample container 23, and the waste liquid is discharged into a waste liquid bottle through the hose.
The first linear motor 43 can vertically move up and down the rod 42 and the waste liquid needle 41. One end of the supporting rod 42 is fixed on the output shaft of the first linear motor 43 so as to be connected with the supporting rod 42, so that the first linear motor 43 can drive the supporting rod 42 and the waste liquid needle 41 to perform lifting motion in the vertical direction.
The supporting rod 42 can support and drive the waste liquid needle 41, and can be made of metal, plastic and other materials, and has certain strength and rigidity. One end of the strut 42 is fixed to an output shaft of the first linear motor 43 so as to be connected to the first linear motor 43, so that the strut 42 can perform a lifting movement in a vertical direction. The other end of the strut 42 is fixed to the waste liquid needle 41 so as to be connected to the waste liquid needle 41, so that the strut 42 can transmit the driving force of the first linear motor 43 to the waste liquid needle 41.
In an exemplary embodiment, referring to fig. 5 and 6, the recycling module 4 further includes a push rod 45, a second linear motor 46, a slide way 47 and a collection box 48, the push rod 45 is mounted on an output shaft of the second linear motor 46, the push rod 45 can push out the sample container 23 mounted on the turntable 21 under the driving of the second linear motor 46, an inlet end of the slide way 47 is disposed adjacent to the periphery of the turntable 21, and an outlet end of the slide way 47 is disposed corresponding to the collection box 48, so that the sample container 23 pushed out by the push rod 45 can slide into the collection box 48 along the slide way 47.
The ejector rod 45 can push and release the sample container 23, and can be made of metal, plastic and other materials, and has certain length and strength. The jack 45 is mounted on an output shaft of the second linear motor 46 so as to be connected to the second linear motor 46, so that the jack 45 can perform a lifting movement in a vertical direction. One end of the ejector rod 45 can be in contact with the bottom or side of the sample container 23, thereby pushing the sample container 23 out of the holder 24 under the drive of the second linear motor 46.
The second linear motor 46 can achieve lifting motion in the vertical direction of the ejector rod 45, and the ejector rod 45 is mounted on an output shaft of the second linear motor 46 so as to be connected with the ejector rod 45, so that the second linear motor 46 can drive the ejector rod 45 to perform lifting motion in the vertical direction.
In other embodiments, the linear motor may be replaced by an electric cylinder or other device, so long as the foregoing lifting function is achieved.
The slide 47 enables means for guiding and transporting the sample container 23, which may be made of metal, plastic or the like, with a certain inclination and smoothness. The inlet end of the slide 47 is disposed adjacent the periphery of the turntable 21 so that the sample containers 23 pushed out by the ejector pins 45 can enter the slide 47. The outlet end of the slide 47 is arranged in correspondence with the collection box 48 so that the sample container 23 sliding along the slide 47 can enter the collection box 48. This design allows for rapid transport and centralized storage of the sample containers 23, thereby improving the efficiency and convenience of the cell detector.
The inlet end of the chute 47 is provided with a sensor which can be used to detect whether the sample container 23 is detached from the holder 24 of the turntable 21 and enters the chute through the inlet end, the arrangement of which sensor can ensure the effectiveness of the recovery operation of the sample container 23.
The collection box 48 can be used for accommodating and protecting the sample container 23, and can be made of metal, plastic and other materials, and has a certain volume. The collection box 48 is disposed in correspondence with the outlet end of the slide 47 so that the sample container 23 sliding along the slide 47 can enter the collection box 48. The collection box 48 may be provided with a cushioning device, such as a soft pad, to reduce the impact of the sample container 23 sliding in.
In an exemplary embodiment, referring to fig. 1, the cell detector further includes a monitoring module 5 and a consumable placement area 6, the monitoring module 5 includes a camera 51, a light source and a display 52, the camera 51 and the light source are disposed corresponding to the rotary loading module 2, the display 52 is connected with the camera 51 to display an image captured by the camera 51, and the consumable placement area 6 is used for placing a pipette tip 61 and a staining solution container 62.
The pipetter 32 of the pipetting module 3 can be moved to the consumable placement area 6, and the pipette tip 61 is loaded at the consumable placement area 6, the pipetter 32 loaded with the pipette tip 61 can be moved to the staining solution container 62, the staining solution in the staining solution container 62 can be sucked, and the staining solution can be moved to the sample loading port 111 of the cell detector 11 after the staining solution is sucked, and the staining solution is added into the cell detector 11 to stain a sample to be measured.
The camera 51 can be implemented by adopting digital, analog and other principles, and has a certain resolution and frame rate. The camera 51 is provided corresponding to the rotary sample module 2 and the consumable placement block 6, so that information on the position, state, etc. of the sample container 23 and whether the pipette tip 61 and the staining solution are loaded can be clearly captured and detected. The camera 51 is connected to the display 52, so that a captured image can be displayed on the display 52 in real time.
The light source can be realized by adopting the principles of white light, colored light, laser and the like, and has certain brightness and color temperature. The light source is arranged corresponding to the rotary loading module 2, so that the light source can be adaptively adjusted and optimized according to different ambient light and detection requirements, and can be cooperated with the camera 51, so that the quality and definition of a shot image are improved.
The display 52 may be implemented using liquid crystal, LED, OLED, etc. principles, with a certain size and resolution. The display 52 is connected to the camera 51 so that a photographed image can be displayed on the display 52 in real time and some interactive functions such as enlargement, reduction, rotation, screenshot, etc. can be provided. This design allows for visual observation and manipulation of the rotary sample module 2, thereby improving the efficiency and flexibility of the cell detector.
The foregoing descriptions of specific exemplary embodiments of the present utility model are presented for purposes of illustration and description. It is not intended to limit the utility model to the precise form disclosed, and obviously many modifications and variations are possible in light of the above teaching. The exemplary embodiments were chosen and described in order to explain the specific principles of the utility model and its practical application to thereby enable one skilled in the art to make and utilize the utility model in various exemplary embodiments and with various modifications as are suited to the particular use contemplated. It is intended that the scope of the utility model be defined by the claims and their equivalents.

Claims (10)

1. A cell detector, comprising:
the detection module comprises a plurality of cell detectors, wherein each cell detector is provided with a sample adding port for adding a sample;
the rotary sample loading module comprises a rotary table, a first rotary motor and a plurality of sample containers arranged on the rotary table, wherein the rotary table is connected with the first rotary motor, and the first rotary motor is used for driving the rotary table to rotate so as to enable the sample containers to move to a manual sample loading position and an automatic sample sampling position;
the pipetting module comprises a transferring assembly and a pipetting device loaded on the transferring assembly, and the pipetting device can be driven by the transferring assembly to move to the automatic sampling position and the sampling port of the cell detector.
2. The cell detector of claim 1, wherein the cell detector comprises a housing, a detection unit, and a flow channel, the sample addition port is provided on the housing, the detection unit is accommodated in the housing, and the flow channel communicates with the sample addition port and the detection unit.
3. The cell detector according to claim 2, wherein a plurality of the cell detectors are arranged in sequence, and a plurality of the cell detectors are arranged within a movement range of the transfer unit.
4. The cell detector according to claim 1, wherein a plurality of clamping members having clamping openings are sequentially provided at intervals along the circumferential direction on the outer periphery of the turntable, the sample container is clamped to the clamping openings, and the sample container can be removed from the clamping openings by external force.
5. The cell testing apparatus according to claim 4, wherein a sensor is provided at the manual loading position, and when the turntable drives the clamping member to move to the manual loading position, a user clamps the sample container to the clamping member to trigger the sensor to generate an electrical signal.
6. The cell detection apparatus according to claim 4, wherein the rotary sample loading module further comprises a cover body, the cover body is arranged above the turntable and the sample container in a covering manner, and a sample loading opening corresponding to the manual sample loading position is formed in the cover body.
7. The cell testing apparatus according to claim 1, wherein the transfer assembly comprises an X-axis moving member, a Y-axis moving member, and a Z-axis moving member, the Y-axis moving member being mounted on the X-axis moving member, the Z-axis moving member being mounted on the Y-axis moving member, the X-axis moving member being configured to drive the pipette to move in the X-axis direction, the Y-axis moving member being configured to drive the pipette to move in the Y-axis direction, and the Z-axis moving member being configured to drive the pipette to move in the Z-axis direction, such that a range of movement of the pipette can cover the testing module and the rotary loading module.
8. The cell detector of claim 1, further comprising a recovery module comprising a waste needle, a strut and a first linear motor, one end of the strut being fixed to an output shaft of the first linear motor, the waste needle being fixed to the other end of the strut, the waste needle being movable to the sample container under the drive of the first linear motor and the second rotary motor to aspirate waste in the sample container.
9. The cell detector of claim 8, wherein the recovery module further comprises a push rod, a second linear motor, a slide way and a collection box, the push rod is mounted on an output shaft of the second linear motor, the push rod can push out a sample container mounted on the rotary table under the driving of the second linear motor, an inlet end of the slide way is arranged adjacent to the periphery of the rotary table, and an outlet end of the slide way is arranged corresponding to the collection box, so that the sample container pushed out by the push rod can slide into the collection box along the slide way.
10. The cell detector of claim 1, further comprising a monitoring module and a consumable placement area, the monitoring module comprising a camera, a light source, and a display, the camera and the light source being positioned in correspondence to the rotary loading module and the consumable placement area, the display being coupled to the camera for displaying images captured by the camera, the consumable placement area being configured to place a pipette tip and a staining solution container.
CN202322151494.0U 2023-08-10 2023-08-10 Cell detector Active CN220603487U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202322151494.0U CN220603487U (en) 2023-08-10 2023-08-10 Cell detector

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202322151494.0U CN220603487U (en) 2023-08-10 2023-08-10 Cell detector

Publications (1)

Publication Number Publication Date
CN220603487U true CN220603487U (en) 2024-03-15

Family

ID=90177464

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202322151494.0U Active CN220603487U (en) 2023-08-10 2023-08-10 Cell detector

Country Status (1)

Country Link
CN (1) CN220603487U (en)

Similar Documents

Publication Publication Date Title
WO2021138963A1 (en) Fully automatic chemiluminescent immune analyzer
CN110045134B (en) Full-automatic chemiluminescence immunoassay instrument and use method thereof
US20060133965A1 (en) Monitoring function-equipped dispensing system and method of monitoring dispensing device
CN107290562B (en) A kind of automatic sample handling system for the detection of sample cell high throughput
CN104535782A (en) Full-automatic immuno-fluorescence quantitative analysis device and implementation method
KR101868824B1 (en) Immune reaction diagonostic automating system
EP3597728B1 (en) Cell transfer device and cell transfer method
CN101978273A (en) Sample preparation system for processing of clinical specimens
JPWO2007132631A1 (en) Cleaning device and automatic analyzer
CN220603487U (en) Cell detector
CN117054674A (en) Cell detector
CN210376404U (en) Full-automatic detection device
CN114965304B (en) Automatic total phosphorus analytical equipment of quality of water
CN110354932B (en) Automatic change liquid operation platform
CN218674742U (en) Chemiluminescence apparatus
CN210665508U (en) Vaginal secretion detector
CN109324200B (en) Sample analyzer
CN103675306A (en) Automatic analysis instrument and system for microfluidic immunodetection chip
US9212976B2 (en) Vision-guided aspiration apparatus and methods
US9664675B2 (en) Automated analyzer
CN210752747U (en) Liquid transfer machine
CN113267498A (en) Basic-level full-automatic body fluid inspection platform and automatic body fluid analysis system
CN217112092U (en) Full-automatic homogeneous phase chemiluminescence instant detection analyzer
CN220867423U (en) Full-automatic molecular diagnosis all-in-one equipment
CN214277598U (en) Standing mechanism of blood testing machine

Legal Events

Date Code Title Description
GR01 Patent grant
GR01 Patent grant