CN220212974U - Spinal cord specimen obtaining and breaking device - Google Patents
Spinal cord specimen obtaining and breaking device Download PDFInfo
- Publication number
- CN220212974U CN220212974U CN202321400540.XU CN202321400540U CN220212974U CN 220212974 U CN220212974 U CN 220212974U CN 202321400540 U CN202321400540 U CN 202321400540U CN 220212974 U CN220212974 U CN 220212974U
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- spinal cord
- breaking
- bone
- sleeve
- specimen
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- 210000000278 spinal cord Anatomy 0.000 title claims abstract description 54
- 210000000988 bone and bone Anatomy 0.000 claims abstract description 28
- 238000007790 scraping Methods 0.000 claims description 16
- 210000002997 osteoclast Anatomy 0.000 claims description 14
- 230000000149 penetrating effect Effects 0.000 claims description 6
- 238000007789 sealing Methods 0.000 claims description 6
- 230000007704 transition Effects 0.000 claims description 4
- 208000010392 Bone Fractures Diseases 0.000 claims 1
- 201000010099 disease Diseases 0.000 abstract description 7
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract description 7
- 230000009286 beneficial effect Effects 0.000 abstract description 3
- 241000251539 Vertebrata <Metazoa> Species 0.000 abstract description 2
- 238000000034 method Methods 0.000 description 10
- 241000699666 Mus <mouse, genus> Species 0.000 description 8
- 241001465754 Metazoa Species 0.000 description 5
- 230000008569 process Effects 0.000 description 5
- 210000000653 nervous system Anatomy 0.000 description 4
- 208000014674 injury Diseases 0.000 description 3
- 208000027418 Wounds and injury Diseases 0.000 description 2
- 230000008859 change Effects 0.000 description 2
- 230000006378 damage Effects 0.000 description 2
- 206010008190 Cerebrovascular accident Diseases 0.000 description 1
- 208000016192 Demyelinating disease Diseases 0.000 description 1
- 241000699670 Mus sp. Species 0.000 description 1
- 206010033892 Paraplegia Diseases 0.000 description 1
- 241000700159 Rattus Species 0.000 description 1
- 208000029033 Spinal Cord disease Diseases 0.000 description 1
- 208000006011 Stroke Diseases 0.000 description 1
- 230000002159 abnormal effect Effects 0.000 description 1
- 230000004075 alteration Effects 0.000 description 1
- 235000013527 bean curd Nutrition 0.000 description 1
- 210000004556 brain Anatomy 0.000 description 1
- 208000026106 cerebrovascular disease Diseases 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 230000003902 lesion Effects 0.000 description 1
- 230000003211 malignant effect Effects 0.000 description 1
- 210000001767 medulla oblongata Anatomy 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000007659 motor function Effects 0.000 description 1
- 210000002161 motor neuron Anatomy 0.000 description 1
- 230000001575 pathological effect Effects 0.000 description 1
- 238000005070 sampling Methods 0.000 description 1
- 230000037152 sensory function Effects 0.000 description 1
- 210000001044 sensory neuron Anatomy 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 230000008733 trauma Effects 0.000 description 1
Abstract
The spinal cord specimen obtaining and breaking device comprises an breaking operation table and a specimen collecting cylinder, wherein four fixing columns are arranged on the breaking operation table, and a tether is connected to the four fixing columns; the bone-breaking operation table is provided with a reciprocating motor and two linear guide rails, the reciprocating motor is used for synchronously driving sliding blocks on the two linear guide rails to reciprocate, and a door-shaped movable frame is fixed on the sliding blocks of the two linear guide rails; in summary, the electric bone breaking assembly and the specimen acquisition member are driven to move through the linear guide rail so as to cut animal vertebrates, and then the specimen acquisition member scrapes and attracts spinal cords and finally collects the spinal cords in the specimen collection cylinder; the utility model has convenient operation, improves the speed and quality of obtaining spinal cord samples, avoids damaging spinal cord samples and staff taking the samples, and is beneficial to the research of diseases.
Description
Technical Field
The utility model relates to a spinal cord specimen obtaining and bone breaking device.
Background
The spinal cord is an important component of the nervous system, the whole length of the spinal cord is unequal in thickness, the spinal cord is positioned in a vertebral canal, the vertebral canal is protected by the spinal cord, the upper end of the spinal cord is connected with a medulla oblongata at the occipital macropore, the lower end of the spinal cord is tapered to form a cone, the cone tip of the spinal cord is continued to form a thin wire, and the end wire is called a terminal wire. The spinal cord is a bridge for communicating the brain and limbs, the front foot is a motor neuron, the rear foot is a sensory neuron, and the most common clinical manifestations of diseases caused by spinal cord lesions such as trauma, cerebrovascular accident, benign malignant occupation of the spinal cord, demyelinating diseases of the nervous system and the like are abnormal sensory or motor function of the nervous system, and paraplegia of a patient below the injury plane possibly occurs seriously. Millions of new cases of spinal cord related diseases are generated each year, so that the research on the structural, functional, physiological and pathological characteristics of the spinal cord has important clinical significance and has important significance for diagnosis and treatment of the related diseases.
At present, the research of spinal cord diseases is usually carried out by using animals such as rats, mice and the like, external conditions are applied to the animals during the experiment, such as medicines of a certain nervous system, external injury factors and the like are applied to construct a disease model, and then spinal cord is taken out for the research of the diseases, including physiological structure change of the spinal cord and related molecular change. The spinal cord is positioned in the vertebral body, and the vertebral body is formed by dozens of vertebrae, so that the spinal cord is taken out, the hard vertebrae are required to be removed to open a spinal cord cavity, the spinal cord is softer like bean curd, the vertebrae are manually broken off by forceps in the prior art, the spinal cord is scraped out by forceps or a curette after being exposed, the operation of the prior method is inconvenient, the vertebrae are required to be broken off one by one, and the spinal cord is possibly damaged, so that the device for conveniently breaking the bone and taking out the spinal cord has important significance.
Disclosure of Invention
The utility model aims to provide a spinal cord specimen obtaining and breaking device, which solves the technical problems of inconvenient operation and long operation time of a method for scraping spinal cord by using forceps to knock open spinal vertebrae in the prior art.
In order to solve the technical problems, the utility model adopts the following technical scheme:
the spinal cord specimen obtaining and breaking device comprises an breaking operation table and a specimen collecting cylinder, wherein four fixing columns are arranged on the breaking operation table, and a tether is connected to the four fixing columns;
the bone-breaking operation table is provided with a reciprocating motor and two linear guide rails, the reciprocating motor is used for synchronously driving sliding blocks on the two linear guide rails to reciprocate, a portal-shaped movable frame is fixed on the sliding blocks of the two linear guide rails, a telescopic rod is installed on the movable frame, the lower end of the telescopic rod is provided with a threaded interface, and an electric bone-breaking assembly or a specimen acquisition piece is installed on the threaded interface of the telescopic rod;
the electric bone breaking assembly comprises a bone breaking motor, a first stud is arranged on the bone breaking motor, the bone breaking motor can be arranged on the threaded interface through the first stud, and a bone breaking cutter head is arranged on a main shaft of the bone breaking motor;
the specimen acquisition part comprises a second stud, a sheet-shaped connecting part is fixed at the lower end of the second stud, the lower end of the sheet-shaped connecting part is connected with a scraping and collecting part, the scraping and collecting part is of a semicircle sphere structure, a negative pressure cavity is arranged in the scraping and collecting part, a plurality of suction holes are uniformly distributed on the concave surface of the scraping and collecting part, and all the suction holes are connected with the negative pressure cavity;
the specimen collection tube comprises a tube body, a tube cover is arranged at the top of the tube body in a sealing manner, two round holes are formed in the tube cover, a connecting tube and a negative pressure tube are respectively arranged in the two round holes in a penetrating manner, the negative pressure tube is connected with a negative pressure cavity, the connecting tube is used for being externally connected with negative pressure equipment, and sealing rings are arranged on the two round holes.
Further, a filter element is arranged in the cylinder body, a through hole is formed in the filter element, the filter element comprises two layers of sieve plates, a sponge layer is arranged between the two layers of sieve plates, the negative pressure pipe penetrates through the through hole, and the lower end of the connecting pipe is located above the filter element.
Further, two groups of flexible pressing auxiliary pieces are arranged on the movable frame and are respectively positioned at two sides of the electric bone breaking component;
each group of flexible pressing auxiliary parts comprises a sleeve and a movable rod, the upper end of the sleeve is fixed on the movable frame, an external thread section is arranged on the sleeve, an adjusting nut is arranged on the external thread section in a threaded manner, the movable rod is arranged in the sleeve in a penetrating manner from bottom to top, an upper baffle ring positioned below the adjusting nut is sleeved on the sleeve, a lower baffle ring is arranged at the lower end of the movable rod, a spring is arranged between the upper baffle ring and the lower baffle ring, a limiting ring is also fixed on the sleeve, the limiting ring is positioned below the upper baffle ring, and the limiting ring is used for limiting the upper baffle ring to move downwards; the lower end of the movable rod is hinged with a pressing plate, and the front part and the rear part of the pressing plate are both arc transition structures which tilt upwards.
Further, the upper end of the threaded interface is fixedly provided with a movable sleeve, the movable sleeve is sleeved on the movable frame and can move along the movable frame, a jacking bolt is arranged on the movable sleeve in a threaded manner, and the inner end of the jacking bolt is jacked on the outer wall of the movable frame.
Compared with the prior art, the utility model has the beneficial effects that: the utility model drives the electric bone breaking component and the specimen acquisition component to move through the linear guide rail so as to realize cutting of animal vertebrates, and then the specimen acquisition component scrapes and attracts the spinal cord, and finally the spinal cord is collected in the specimen collection cylinder; the utility model has convenient operation, improves the speed and quality of obtaining spinal cord samples, avoids damaging spinal cord samples and staff taking the samples, and is beneficial to the research of diseases.
Drawings
The accompanying drawings are included to provide a further understanding of the utility model and are incorporated in and constitute a part of this specification, illustrate the utility model and together with the embodiments of the utility model, serve to explain the utility model. In the drawings:
FIG. 1 is a schematic view of a spinal cord specimen acquisition osteotomy device of the present utility model;
FIG. 2 is a schematic view of an electrically powered osteoclast assembly;
FIG. 3 is a schematic illustration of the connection of a specimen collection cartridge to a specimen acquisition member;
FIG. 4 is a schematic view of the structure of the filter element;
fig. 5 is a schematic structural view of the flexible pressing aid.
Detailed Description
The following description of the embodiments of the present utility model will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present utility model, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the utility model without making any inventive effort, are intended to be within the scope of the utility model.
The present utility model is described in further detail below with reference to examples.
As shown in fig. 1 to 5, a specific embodiment 1 of a spinal cord specimen obtaining and osteoclast device provided by the present utility model is as follows:
the device comprises an osteoclast operation table 1 and a sample collection tube 2, wherein four fixing columns 3 are arranged on the osteoclast operation table 1, tether ropes are connected to the four fixing columns 3, and four limbs of animals can be fixed on the four fixing columns 3 through the tether ropes;
the bone-breaking operation table 1 is provided with a reciprocating motor and two linear guide rails 4, the reciprocating motor is used for synchronously driving sliding blocks 5 on the two linear guide rails 4 to reciprocate, a door-shaped movable frame 6 is fixed on the sliding blocks 5 of the two linear guide rails 4, a telescopic rod 7 is installed on the movable frame 6, the lower end of the telescopic rod 7 is provided with a threaded interface 8, and an electric bone-breaking assembly 9 or a specimen acquisition member is installed on the threaded interface 8 of the telescopic rod 7; in order to conveniently adjust the transverse position of the electric bone breaking assembly 9 or the specimen acquisition member to align with the vertebra of the mouse, the threaded interface 8 of the embodiment is arranged to be movable on the movable frame 6, specifically, the upper end of the threaded interface 8 is fixedly provided with a movable sleeve 10, the movable sleeve 10 is sleeved on the movable frame 6, the movable sleeve 10 can move along the movable frame 6, a jacking bolt 11 is arranged on the movable sleeve 10 in a threaded manner, the inner end of the jacking bolt 11 is jacked on the outer wall of the movable frame 6, the movable sleeve 10 moves on the movable frame 6 to adjust the position of the threaded interface 8, then the threaded interface is fixed by the jacking bolt 11, and finally the electric bone breaking assembly 9 or the specimen acquisition member is aligned with the vertebra of the mouse, so that the sampling operation is convenient;
the electric bone breaking assembly 9 comprises a bone breaking motor 12, a first stud 13 is arranged on the bone breaking motor 12, the bone breaking motor 12 can be arranged on the threaded interface 8 through the first stud 13, and a bone breaking cutter head 14 is arranged on a main shaft of the bone breaking motor 12;
the specimen acquisition part comprises a second stud 15, a sheet-shaped connecting part 16 is fixed at the lower end of the second stud 15, a scraping and collecting part 17 is connected at the lower end of the sheet-shaped connecting part 16, the scraping and collecting part 17 is of a semicircle sphere structure, a negative pressure cavity is arranged in the scraping and collecting part 17, a plurality of suction holes 18 are uniformly distributed on the concave surface of the scraping and collecting part 17, and all the suction holes 18 are connected with the negative pressure cavity;
the specimen collection tube 2 comprises a tube 19, a tube cover 20 is arranged at the top of the tube 19 in a sealing manner, two round holes are formed in the tube cover 20, a connecting tube 21 and a negative pressure tube 22 are respectively arranged in the two round holes in a penetrating manner, the negative pressure tube 22 is connected with a negative pressure cavity, the connecting tube 21 is used for being externally connected with negative pressure equipment, and sealing rings are arranged on the two round holes.
The method for obtaining spinal cord by using the spinal cord specimen obtaining bone-breaking device of the present embodiment is as follows: firstly, an animal is prone to an osteoclast operation table 1, four limbs of the animal are fixed on a fixed column 3 by using a tether, then an upper opening of a spinal cord cavity is cut by using scissors or other instruments, a telescopic rod 7 is adjusted to be of a proper length, the length ensures that an osteoclast cutter disc 14 can cut a vertebra, a movable sleeve 10 is adjusted to enable the osteoclast cutter disc 14 to be aligned with the vertebra of a mouse, then an osteoclast motor 12 and a reciprocating motor are started, the reciprocating motor drives a sliding block on a linear guide rail 4 to move, and then a movable frame 6 is driven to move along the horizontal direction, in the moving process, the osteoclast motor 12 drives the osteoclast cutter disc 14 to rotate, the osteoclast cutter disc 14 moves along the vertebra, and a seam is cut on the upper part of the vertebra by the osteoclast cutter disc 14;
then the bone-breaking motor 12 is taken down from the screw interface 8, the second stud 15 is arranged on the screw interface 8, at the moment, the sheet-shaped connecting piece 16 corresponds to the seam on the vertebra, the negative pressure equipment is started, the reciprocating motor is started again, the sheet-shaped connecting piece 16 passes through the seam on the vertebra, the scraping collecting piece 17 enters the vertebra, along with the movement of the movable frame 6, the scraping collecting piece 17 moves in the vertebra, the scraping collecting piece 17 scrapes the spinal cord in the moving process, under suction, the spinal cord enters the negative pressure cavity through the suction hole 18, and then enters the sample collecting cylinder 2 through the negative pressure cavity and the negative pressure pipe 22, and the taking and collecting of the spinal cord are completed.
The utility model provides a specific embodiment 2 of a spinal cord specimen acquisition and bone breaking device:
unlike embodiment 1, in order to prevent spinal cord in the specimen collection tube 2 from entering the connecting tube 21, in this embodiment, a filter member 23 is disposed in the tube 19, a through hole 24 is formed in the filter member 23, the filter member 23 includes two layers of sieve plates 25, a sponge layer 26 is disposed between the two layers of sieve plates 25, the negative pressure tube 22 passes through the through hole 24, and the lower end of the connecting tube 21 is located above the filter member 23.
The removed spinal cord is located below the filter element 23 and the connecting tube 21 is located above the filter element 23, so that the filter element 23 filters the spinal cord from entering the connecting tube 21.
Specific example 3 of a spinal cord specimen acquisition and osteosynthesis device provided by the utility model:
the difference from the specific embodiment 1 is that two sets of flexible pressing aids 27 are mounted on the movable frame 6, the two sets of flexible pressing aids 27 being located on both sides of the electric bone breaking assembly 9, respectively;
each group of flexible pressing auxiliary parts 27 comprises a sleeve 28 and a movable rod 29, the upper end of the sleeve 28 is fixed on the movable frame 6, an external thread section 30 is arranged on the sleeve 28, an adjusting nut 31 is arranged on the external thread section 30 in a threaded manner, the movable rod 29 is arranged in the sleeve 28 in a penetrating manner from bottom to top, an upper baffle ring 32 positioned below the adjusting nut 31 is sleeved on the sleeve 28, a lower baffle ring 33 is arranged at the lower end of the movable rod 29, a spring 34 is arranged between the upper baffle ring 32 and the lower baffle ring 33, a limiting ring 35 is also fixed on the sleeve 28, the limiting ring 35 is positioned below the upper baffle ring 32, and the limiting ring 35 is used for limiting the downward movement of the upper baffle ring 32; the lower end of the movable rod 29 is hinged with a pressing plate 36, the front part and the rear part of the pressing plate 36 are both arc-shaped transition structures 37 which tilt upwards, and the arc-shaped transition structures 37 facilitate the movement of the pressing plate 36 on an uneven mouse body.
During the process of bone-breaking and spinal cord acquisition, the two sets of flexible pressing auxiliary pieces 27 can adapt to the body of the pressing mouse to prevent the body from moving, specifically, the pressing plate 36 is positioned on the body of the mouse, at this time, the spring 34 is in a compressed state, along with the movement of the movable frame 6, the pressing plate 36 moves on the uneven body of the mouse, and along with the fluctuation of the body, the movable rod 29 moves in the sleeve 28, but the spring 34 is always in a compressed state, so that the pressing plate 36 is pressed and contacted on the body of the mouse, preferably, the upward moving distance of the upper baffle ring 32 is changed by adjusting the position of the nut 31 on the external thread section 30, so that the telescopic length of the spring 34 is changed, and the pressing force of the pressing plate 36 is adjusted.
It should be noted that in this document, terms such as "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus.
Although embodiments of the present utility model have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made therein without departing from the principles and spirit of the utility model, the scope of which is defined in the appended claims and their equivalents.
Claims (4)
1. The spinal cord specimen obtains the broken bone device, its characterized in that: comprises an osteoclast operation table and a specimen collection tube, wherein four fixing columns are arranged on the osteoclast operation table, and a tether is connected to the four fixing columns;
the bone-breaking operation table is provided with a reciprocating motor and two linear guide rails, the reciprocating motor is used for synchronously driving sliding blocks on the two linear guide rails to reciprocate, a portal-shaped movable frame is fixed on the sliding blocks of the two linear guide rails, a telescopic rod is installed on the movable frame, the lower end of the telescopic rod is provided with a threaded interface, and an electric bone-breaking assembly or a specimen acquisition piece is installed on the threaded interface of the telescopic rod;
the electric bone breaking assembly comprises a bone breaking motor, a first stud is arranged on the bone breaking motor, the bone breaking motor can be arranged on the threaded interface through the first stud, and a bone breaking cutter head is arranged on a main shaft of the bone breaking motor;
the specimen acquisition part comprises a second stud, a sheet-shaped connecting part is fixed at the lower end of the second stud, the lower end of the sheet-shaped connecting part is connected with a scraping and collecting part, the scraping and collecting part is of a semicircle sphere structure, a negative pressure cavity is arranged in the scraping and collecting part, a plurality of suction holes are uniformly distributed on the concave surface of the scraping and collecting part, and all the suction holes are connected with the negative pressure cavity;
the specimen collection tube comprises a tube body, a tube cover is arranged at the top of the tube body in a sealing manner, two round holes are formed in the tube cover, a connecting tube and a negative pressure tube are respectively arranged in the two round holes in a penetrating manner, the negative pressure tube is connected with a negative pressure cavity, the connecting tube is used for being externally connected with negative pressure equipment, and sealing rings are arranged on the two round holes.
2. The spinal cord specimen acquisition osteosynthesis device of claim 1, wherein: the cylinder body is internally provided with a filter element, the filter element is provided with a through hole, the filter element comprises two layers of sieve plates, a sponge layer is arranged between the two layers of sieve plates, the negative pressure pipe penetrates through the through hole, and the lower end of the connecting pipe is positioned above the filter element.
3. The spinal cord specimen acquisition osteosynthesis device of claim 1, wherein: two groups of flexible pressing auxiliary pieces are arranged on the movable frame and are respectively positioned at two sides of the electric bone breaking component;
each group of flexible pressing auxiliary parts comprises a sleeve and a movable rod, the upper end of the sleeve is fixed on the movable frame, an external thread section is arranged on the sleeve, an adjusting nut is arranged on the external thread section in a threaded manner, the movable rod is arranged in the sleeve in a penetrating manner from bottom to top, an upper baffle ring positioned below the adjusting nut is sleeved on the sleeve, a lower baffle ring is arranged at the lower end of the movable rod, a spring is arranged between the upper baffle ring and the lower baffle ring, a limiting ring is also fixed on the sleeve, the limiting ring is positioned below the upper baffle ring, and the limiting ring is used for limiting the upper baffle ring to move downwards; the lower end of the movable rod is hinged with a pressing plate, and the front part and the rear part of the pressing plate are both arc transition structures which tilt upwards.
4. The spinal cord specimen acquisition osteosynthesis device of claim 1, wherein: the upper end of the threaded interface is fixedly provided with a movable sleeve, the movable sleeve is sleeved on the movable frame and can move along the movable frame, a jacking bolt is arranged on the movable sleeve in a threaded manner, and the inner end of the jacking bolt is jacked on the outer wall of the movable frame.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202321400540.XU CN220212974U (en) | 2023-06-05 | 2023-06-05 | Spinal cord specimen obtaining and breaking device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202321400540.XU CN220212974U (en) | 2023-06-05 | 2023-06-05 | Spinal cord specimen obtaining and breaking device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN220212974U true CN220212974U (en) | 2023-12-22 |
Family
ID=89187886
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202321400540.XU Active CN220212974U (en) | 2023-06-05 | 2023-06-05 | Spinal cord specimen obtaining and breaking device |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN220212974U (en) |
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2023
- 2023-06-05 CN CN202321400540.XU patent/CN220212974U/en active Active
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