CN220194894U - Reagent tube for detection device and detection device - Google Patents

Abstract

The utility model discloses a reagent tube for a detection device and the detection device, the reagent tube comprises: the gun head is provided with a liquid outlet at the first end; the first end of the pipe body is detachably connected with the second end of the gun head and used for containing liquid, and a first limiting step is formed on the peripheral wall of the pipe body; the extrusion cover is sleeved at the second end of the pipe body and can axially move towards the first limiting step, and extrusion ribs for applying lateral extrusion force to the pipe body are formed on the inner peripheral wall of the extrusion cover. The reagent tube for the detection equipment and the detection equipment are simple in structure and can play a role in improving quantitative pipetting accuracy.

Description

Reagent tube for detection device and detection device

Technical Field

The utility model relates to the technical field of detection instruments, in particular to a reagent tube for detection equipment and the detection equipment.

Background

In performing biological or medical tests, a test person typically uses a reagent tube to store, transfer a reagent or liquid sample, and drop the reagent or liquid sample into the interior of the reagent to be tested for testing analysis. The detection personnel most need carry out quantitative pipetting through the mode of artificial judgement when using reagent pipe among the prior art to carry out reagent or sample transfer, like prior art CN204365334U discloses a scale pipette, including pipette main part and sharp mouth, the top of pipette main part has conical pipette mouth, conical pipette mouth opening part aperture is greater than the aperture of pipette main part, pipette main part surface is provided with the scale, the design has the liquid reserve pipe in the middle of the pipette main part, install the piston switch on the pipette main part, during the pipetting, operating personnel observe whether reagent or liquid sample flush with the scale in the pipette main part through the human eye and realize quantitative pipetting. However, when a large amount of quantitative pipetting is performed, fatigue is determined manually, so that the amount of pipetting of a reagent or a liquid sample is deviated, and the reagent or the liquid sample is not easy to perceive, so that the subsequent detection result is inaccurate.

Disclosure of Invention

The utility model aims to provide a reagent tube for detection equipment and detection equipment, which have simple structures and can play a role in improving quantitative pipetting accuracy.

In order to achieve the above object, a first aspect of the present utility model provides a reagent tube for a detection apparatus, the reagent tube comprising:

the gun head is provided with a liquid outlet at the first end;

the first end of the pipe body is detachably connected with the second end of the gun head and used for containing liquid, and a first limiting step is formed on the peripheral wall of the pipe body;

the extrusion cover is sleeved at the second end of the pipe body and can axially move towards the first limiting step, and extrusion ribs for applying lateral extrusion force to the pipe body are formed on the inner peripheral wall of the extrusion cover.

In the embodiment of the utility model, the pipe body comprises a pressed part for bearing lateral extrusion force and a first limiting part positioned on one side of the pressed part close to the gun head, the extrusion rib comprises an extrusion part and a second limiting part, the extrusion part is used for being matched with the pressed part, and the second limiting part is used for being matched with the first limiting part.

In an embodiment of the utility model, the pipe body further comprises a guiding part which is positioned at one side of the pressed part away from the first limiting part and is used for guiding the pipe body when entering the extrusion cover.

In the embodiment of the utility model, a first limiting convex ring and a second limiting convex ring which are distributed at intervals are also formed on the pipe body, and limiting protrusions which are used for being clamped between the first limiting convex ring and the second limiting convex ring are formed on the inner peripheral wall of the extrusion cover.

In an embodiment of the utility model, the gun head comprises a channel part and a connecting part, wherein the liquid outlet is formed on the channel part, the connecting part is arranged on the outer periphery side of the channel part and forms an internal thread on the inner peripheral wall, and the pipe body is formed with an external thread for matching with the internal thread.

In the embodiment of the utility model, the inner part of the pipe body is provided with a containing cavity for containing liquid, and one end of the channel part, which is far away from the liquid outlet, extends into the containing cavity and is clung to the inner peripheral wall of the containing cavity.

In the embodiment of the utility model, the first guide surface is formed on the peripheral wall of the channel part near one end of the accommodating cavity, and the first guide surface is in an inverted truncated cone shape.

In the embodiment of the utility model, a second limiting step for limiting the movement of the connecting part is also formed on the outer peripheral wall of the pipe body.

In an embodiment of the utility model, the reagent vessel further comprises a protective cover detachably arranged on the gun head.

A second aspect of the utility model provides a detection device comprising a reagent tube as described above for a detection device.

According to the technical scheme, the reagent tube comprises a gun head, a tube body and an extrusion cover, wherein the tube body is detachably connected with one end, far away from a liquid outlet, of the gun head and is used for accommodating liquid, and a first limiting step is formed on the peripheral wall of the tube body; the extrusion cap is arranged on the pipe body and is positioned at one side of the first limiting step away from the gun head, and extrusion ribs for applying lateral extrusion force to the pipe body are formed on the inner peripheral wall of the extrusion cap. The pressing cover is pushed to enable the pressing cover to move towards the direction where the first limiting step is located, in the moving process of the pressing cover, the lateral pressing force is applied to the pipe body by the pressing ribs, the pipe body is deformed, the air pressure inside the reagent pipe is increased after the pipe body is deformed, and liquid can be discharged outwards through the liquid outlet. When the extrusion cover moves a preset distance relative to the tube body, the extrusion cover cannot be enabled to move continuously no matter how much force is applied to the extrusion cover because the first limiting step can block the extrusion cover, so that the extrusion cover can only move a preset distance relative to the tube body, namely, the space inside the reagent tube can only be reduced by a preset size, and correspondingly, the liquid inside the reagent tube can only be extruded outwards by a preset volume, so that the quantitative pipetting accuracy of the reagent tube is improved.

Drawings

The accompanying drawings are included to provide a further understanding of embodiments of the utility model and are incorporated in and constitute a part of this specification, illustrate embodiments of the utility model and together with the description serve to explain, without limitation, the embodiments of the utility model. In the drawings:

FIG. 1 is a schematic cross-sectional view of a reagent vessel according to the present utility model;

FIG. 2 is a schematic view of the overall structure of a reagent vessel according to the present utility model;

FIG. 3 is a schematic view of the structure of the pipe body of the present utility model;

FIG. 4 is a schematic view of the structure of the extrusion cap of the present utility model;

FIG. 5 is a schematic cross-sectional view of the extrusion cap of the present utility model;

FIG. 6 is a schematic view of the gun head according to the present utility model;

fig. 7 is a schematic cross-sectional structure of a gun head according to the present utility model.

Description of the reference numerals

1-gun head; 101-a liquid outlet; 102-a channel portion; 1021-pipetting channel; 1022-a first channel segment; 1023-a second channel segment; 1024-third channel segment; 1025-a first tapered transition section; 1026-a second conical transition section; 103-a connection; 1031-a first guide surface; 2-a tube body; 201-a first limit step; 202-a compression section; 203-a first limit part; 204-a guide; 205-a first limiting convex ring; 206-a second limiting convex ring; 207-a second limit step; 208-a receiving cavity; 209-guide ribs; 3-pressing the cover; 301-extruding ribs; 3011-an extrusion; 3012-a second limit part; 302-limit protrusions; 4-protecting cover; 5-cotton swab.

Detailed Description

The following describes specific embodiments of the present utility model in detail with reference to the drawings. It should be understood that the detailed description and specific examples, while indicating and illustrating the utility model, are not intended to limit the utility model.

In one embodiment of the present utility model, there is provided a novel reagent vessel, as shown in FIGS. 1 to 2, comprising:

the gun head 1, a liquid outlet 101 is formed at the first end of the gun head 1;

the pipe body 2, the first end of the pipe body 2 is detachably connected with the second end of the gun head 1 and used for containing liquid, and a first limiting step 201 is formed on the peripheral wall of the pipe body 2;

the extrusion cover 3 is sleeved at the second end of the pipe body 2 and can axially move towards the first limiting step 201, and extrusion ribs 301 for applying lateral extrusion force to the pipe body 2 are formed on the inner peripheral wall of the extrusion cover 3.

Specifically, a containing cavity 208 for containing liquid is formed in the tube body 2, a pipetting channel 1021 for communicating with the containing cavity 208 is formed in the gun head 1, and the liquid outlet 101 is positioned at one end of the pipetting channel 1021 away from the containing cavity 208; the liquid is stored in advance in the accommodating chamber 208 in this embodiment. Before pipetting, the inspector firstly removes the squeezing cover 3 from the tube body 2, then uses the cotton swab 5 to complete nucleic acid sampling, unscrews the gun head 1 after sampling is completed so as to place the cotton swab 5 in the accommodating cavity 208, then screws the gun head 1 and shakes the whole reagent tube, so that the nucleic acid in the cotton swab 5 and the liquid in the accommodating cavity 208 are fully mixed, and the whole reagent tube is inverted after the nucleic acid and the liquid in the accommodating cavity 208 are fully mixed. Since the gun head 1 can discharge the redundant air in the inside of the reagent tube (the inside of the reagent tube in the embodiment is composed of the accommodating cavity 208 and the pipetting channel 1021) through the liquid outlet 101 in the screwing process, after the gun head 1 is screwed, the air pressure outside the reagent tube and the pressure inside the reagent tube reach balance, and the inside of the reagent tube forms a relative sealing state, so that even if the reagent tube is integrally inverted, the liquid in the reagent tube cannot leak out through the liquid outlet 101.

After the whole reagent tube is inverted, a detecting personnel covers the extrusion cover 3 at one end of the tube body 2 far away from the gun head 1 and pushes the extrusion cover 3 downwards (in the embodiment, equipment such as an electric push rod or a hydraulic push rod can also be adopted to push the extrusion cover 3), the extrusion cover 3 moves towards the direction of the first limiting step 201, in the moving process, the extrusion ribs 301 apply lateral extrusion force to the tube body 2 to enable the tube body 2 to deform, the volume of the accommodating cavity 208 after the tube body 2 deforms is reduced, the space inside the reagent tube is reduced, the air pressure inside the reagent tube is increased, and liquid inside the reagent tube can be discharged outwards through the liquid outlet 101. After the extrusion cover 3 moves a preset distance relative to the tube body 2, the extrusion cover 3 cannot move continuously no matter how much force is applied to the extrusion cover 3 by a detection person because the first limiting step 201 can block the extrusion cover 2, so that the extrusion cover 3 can only move a preset distance relative to the tube body 2, that is, the space inside the reagent tube can only be reduced by a preset size, correspondingly, the liquid inside the reagent tube can only be extruded outwards by a preset volume, and the quantitative pipetting function of the reagent tube is realized. This reagent pipe simple structure, the detection personnel need not to control the dynamics size that is applyed to extrusion lid 3 when using it to carry out the pipettor and can realize quantitative pipetting, need not artificial judgement, also can not produce the pipetting deviation because of fatigue operation, can guarantee the accuracy of quantitative pipetting better, has promoted the accuracy of pipetting.

In one embodiment of the present utility model, the number of the pressing ribs 301 is plural, and the plural pressing ribs 301 are uniformly distributed at intervals on the inner peripheral wall of the pressing cap 3 so as to uniformly apply the lateral pressing force to the tube 2.

In one embodiment of the present utility model, as shown in fig. 3 to 5, the pipe body 2 includes a compression part 202 for receiving a lateral compression force and a first limiting part 203 located on one side of the compression part 202 near the gun head 1, the compression rib 301 includes a compression part 3011 and a second limiting part 3012, the compression part 3011 is used for matching with the compression part 202, that is, the compression part 3011 of the compression rib 301 applies the lateral compression force to the compression part 202 of the pipe body 2, the compression part 3011 deforms, so that the volume of the accommodating cavity 208 changes; the second limiting portion 3012 is used for being matched with the first limiting portion 203, an inclined first limiting surface is formed on the first limiting portion 203, an inclined second limiting surface is formed on the second limiting portion 3012, when the extrusion cover 3 moves by a preset distance, the first limiting surface and the second limiting surface are in contact and extrusion occurs, namely, the first limiting portion 203 can also block the movement of the second limiting portion 3012 to realize the movement of the extrusion cover 3, and the accuracy of the movement distance of the extrusion cover 3 is further guaranteed.

In one embodiment of the present utility model, the pipe body 2 further includes a guiding portion 204 located at a side of the pressure receiving portion 202 away from the first limiting portion 203 and used for guiding the pipe body 2 when entering the extruding cover 3, and an inclined second guiding surface is formed on the guiding portion 204, where the second guiding surface is in a shape of a truncated cone, so that an outer diameter of a side of the second guiding surface, which is close to the pressure receiving portion 202, is larger than an outer diameter of a side of the second guiding surface, which is away from the pressure receiving portion 202, and further, it is easier for a detecting person to cover the extruding cover 3 on the pipe body 2, which is beneficial to improving convenience of operation of the detecting person.

In one embodiment of the present utility model, the pipe body 2 is further formed with a first limiting convex ring 205 and a second limiting convex ring 206 which are distributed at intervals, and a limiting protrusion 302 for being clamped between the first limiting convex ring 205 and the second limiting convex ring 206 is formed on the inner peripheral wall of the extrusion cover 3. Specifically, the first limiting convex ring 205, the second limiting convex ring 206 and the limiting convex 302 are arranged to form a whole body with the pipe body 2 and the extrusion cover 3, so that accidental loss of the extrusion cover 3 can be effectively avoided. Before the inspector performs the extrusion operation, the limiting protrusion 302 is clamped between the first limiting collar 205 and the second limiting collar 206; after the extrusion cover 3 is extruded, the limiting protrusion 302 is separated from the space between the first limiting protrusion ring 205 and the second limiting protrusion ring 206 and moves towards the direction close to the first limiting step 201, and after the liquid transfer is completed, a detection personnel applies a force in the opposite direction to the extrusion cover 3 again so that the limiting protrusion 302 is clamped between the first limiting protrusion ring 205 and the second limiting protrusion ring 206 again. Further, the number of the limiting convex rings in the embodiment is not limited to two, but may be three, four or other numbers, when the number of the limiting convex rings is three, besides the first limiting convex ring 205 and the second limiting convex ring 206, another limiting convex ring is a third limiting convex ring, and when the number of the limiting convex rings is more, the naming of the remaining limiting convex rings is similar, such as a fourth limiting convex ring, a fifth limiting convex ring and the like; when the number of the limit convex rings is not limited to two, the limit convex rings 302 on the same circumference of the extrusion cover 3 are not limited to one group (the number of one group of limit convex rings 302 is not limited), if the number of the limit convex rings is N, the number of the limit convex rings 302 on the same circumference of the extrusion cover 3 is N-1 groups, and the limit convex rings 302 of adjacent groups are distributed at intervals along the axial direction of the extrusion cover 3, so that the limit convex rings 302 of the same group can be clamped between the adjacent limit convex rings.

In one embodiment of the present utility model, the inner peripheral wall of the accommodating cavity 208 is further provided with the guiding rib 209 for guiding the flow of the liquid, and the setting direction of the guiding rib 209 is consistent with the axial direction of the tube body 2, so that the adhesion between the mixed liquid (the mixed substance of the liquid and the nucleic acid) in the accommodating cavity 208 and the inner peripheral wall of the accommodating cavity 208 can be reduced, the mixed liquid can be smoothly led out from the accommodating cavity 208 with limited inner space when the reagent tube is integrally inverted, the smoothness of the mixed liquid flowing from the accommodating cavity 208 to the pipetting channel 1021 is enhanced, the mixed liquid is prevented from being retained on the inner peripheral wall of the accommodating cavity 208, and the accuracy of quantitative pipetting is further improved.

In one embodiment of the present utility model, the gun head 1 includes a passage portion 102 and a connection portion 103, the liquid outlet 101 is formed on the passage portion 102, the connection portion 103 is provided on an outer peripheral side of the passage portion 102 and forms an internal thread on an inner peripheral wall, and the pipe body 2 is formed with an external thread for mating with the internal thread. Specifically, as shown in fig. 6 to 7, a pipetting channel 1021 is formed on the channel portion 102, and liquid in the tube 2 can flow out from the liquid outlet 101 after flowing through the pipetting channel 1021; the connection part 103 and the tube body 2 are detachably connected through threaded fit, so that a inspector can unscrew the gun head 1 and put the cotton swab 5 with nucleic acid into the tube body 2, and then the gun head 1 can be screwed down so as to invert the whole reagent tube.

In one embodiment of the present utility model, the tube body 2 is internally formed with a receiving chamber 208 for receiving a liquid, and one end of the channel portion 102 remote from the liquid outlet 101 extends into the receiving chamber 208 and is in close contact with an inner peripheral wall of the receiving chamber 208. Specifically, in this embodiment, an annular cavity is formed between the channel portion 102 and the connecting portion 103, and an interference fit is formed between the end of the channel portion 102 away from the liquid outlet 101 and the accommodating cavity 208, which is beneficial to further enhancing the tightness of the interior of the mobile device, so that the liquid can flow from the accommodating cavity 208 to the pipetting channel 1021 directly without entering the annular cavity.

In one embodiment of the present utility model, the pipetting channel 1021 includes a first channel section 1022, a second channel section 1023 and a third channel section 1024 which are sequentially connected back and forth, the liquid outlet 101 is located on the third channel section 1024, and a first tapered transition section 1025 is further disposed between the first channel section 1022 and the second channel section 1023, so as to promote the smoothness of the flow of the liquid entering the second channel section 1023 from the first channel section 1022; a second tapered transition section 1026 is also provided between the second channel section 1023 and the third channel section 1024 to promote smooth flow of liquid from the second channel section 1023 into the third channel section 1024. Further, the first channel section 1022 has an inner diameter in the range of 7mm to 8mm, and the difference between the inner diameter of the receiving chamber 208 near the end of the first channel section 1022 and the inner diameter of the first channel section 1022 is in the range of 2mm to 3mm, which is arranged to allow liquid to quickly flow from the receiving chamber 208 into the first channel section 1022; the inner diameter range of the third channel section 1024 is 0.4mm-0.6mm, the length range of the third channel section 1024 is 5mm-6mm, the inner diameter of the numerical range enables the third channel section 1024 to be slender, the precision of the reagent tube in liquid outlet is further improved, the pressure balance between the inside of the reagent tube and the outside of the reagent tube is maintained after the gun head 1 is screwed, and the unexpected leakage of the liquid in the reagent tube is avoided; the difference between the inner diameter of the second channel section 1023 and the inner diameter of the third channel section 1024 ranges from 1mm to 2mm, and the difference between the inner diameter of the first channel section 1022 and the inner diameter of the second channel section 1023 ranges from 5mm to 6mm, which arrangement makes the second channel section 1023 a transition between the first channel section 1022 and the third channel section 1024, which provides a moving transition for the liquid.

In one embodiment of the present utility model, an inclined first guiding surface 1031 is formed on the peripheral wall of the end of the channel portion 102 near the accommodating cavity 208, and the first guiding surface 1031 is in an inverted circular truncated cone shape, so that the outer diameter of the end of the first guiding surface 1031 near the accommodating cavity 208 is smaller than the outer diameter of the end of the first guiding surface 1031 far from the accommodating cavity 208, so that the small outer diameter portion of the channel portion 102 extends into the accommodating cavity 208 first, and convenience in mounting the gun head 1 is further enhanced.

In one embodiment of the present utility model, a second limiting step 207 for limiting the movement of the connection portion 103 is further formed on the outer circumferential wall of the pipe body 2. Specifically, the second limiting step 207 is annular, and after the screw thread fit between the connecting portion 103 and the pipe body 2 reaches the preset length, due to the blocking of the second limiting step 207, the detection personnel cannot continuously screw the gun head 1 again, and further the movement limiting of the connecting portion 103 is achieved, so that the connection tightness is ensured, and meanwhile the operation time of the detection personnel is saved.

In one embodiment of the utility model, the reagent vessel further comprises a protective cap 4 removably arranged on the gun head 1. Specifically, the protective cover 4 is used for protecting the gun head 1 and also preventing external impurities from entering the internal polluted liquid of the mobile device through the liquid outlet 101; the outer peripheral wall of the second channel section 1023 is provided with external threads, and the inner peripheral wall of the protective cover 4 is provided with internal threads matched with the external threads, so that the detachable connection between the protective cover 4 and the gun head 1 is realized.

In another embodiment of the present utility model, a novel pipette is provided, which includes the reagent tube of the above embodiment.

The preferred embodiments of the present utility model have been described in detail above with reference to the accompanying drawings, but the present utility model is not limited thereto. Within the scope of the technical idea of the utility model, a plurality of simple variants of the technical proposal of the utility model can be carried out, comprising that each specific technical feature is combined in any suitable way, and in order to avoid unnecessary repetition, the utility model does not need to be additionally described for various possible combinations. Such simple variations and combinations are likewise to be regarded as being within the scope of the present disclosure.

In the present utility model, unless explicitly specified and limited otherwise, the terms "mounted," "connected," "secured," and the like are to be construed broadly, and may be, for example, fixedly connected, detachably connected, or integrally formed; may be mechanically connected, may be electrically connected or may be in communication with each other; either directly or indirectly, through intermediaries, or both, may be in communication with each other or in interaction with each other, unless expressly defined otherwise. The specific meaning of the above terms in the present utility model can be understood by those of ordinary skill in the art according to the specific circumstances.

In the present utility model, unless expressly stated or limited otherwise, a first feature "up" or "down" a second feature may be the first and second features in direct contact, or the first and second features in indirect contact via an intervening medium. Moreover, a first feature being "above," "over" and "on" a second feature may be a first feature being directly above or obliquely above the second feature, or simply indicating that the first feature is level higher than the second feature. The first feature being "under", "below" and "beneath" the second feature may be the first feature being directly under or obliquely below the second feature, or simply indicating that the first feature is less level than the second feature.

While embodiments of the present utility model have been shown and described above, it will be understood that the above embodiments are illustrative and not to be construed as limiting the utility model, and that variations, modifications, alternatives and variations may be made to the above embodiments by one of ordinary skill in the art within the scope of the utility model.

Claims (10)

1. A reagent tube for a detection apparatus, the reagent tube comprising:

the gun comprises a gun head (1), wherein a liquid outlet (101) is formed at the first end of the gun head (1);

the gun comprises a tube body (2), wherein a first end of the tube body (2) is detachably connected with a second end of the gun head (1) and used for containing liquid, and a first limiting step (201) is formed on the peripheral wall of the tube body (2);

the extrusion cover (3) is sleeved at the second end of the pipe body (2) and can axially move towards the first limiting step (201), and extrusion ribs (301) for applying lateral extrusion force to the pipe body (2) are formed on the inner peripheral wall of the extrusion cover (3).

2. The reagent tube for a detecting apparatus according to claim 1, wherein the tube body (2) includes a pressed portion (202) for receiving the lateral pressing force and a first limit portion (203) located on a side of the pressed portion (202) near the gun head (1), the pressing rib (301) includes a pressing portion (3011) and a second limit portion (3012), the pressing portion (3011) is for cooperation with the pressed portion (202), and the second limit portion (3012) is for cooperation with the first limit portion (203).

3. A reagent tube for a test device according to claim 2, wherein the tube body (2) further comprises a guide portion (204) located at a side of the pressure receiving portion (202) remote from the first limiting portion (203) for guiding the tube body (2) when entering the squeeze cap (3).

4. The reagent tube for the detection device according to claim 1, wherein the tube body (2) is further formed with a first limiting convex ring (205) and a second limiting convex ring (206) which are distributed at intervals, and a limiting protrusion (302) for being clamped between the first limiting convex ring (205) and the second limiting convex ring (206) is formed on the inner peripheral wall of the extrusion cover (3).

5. The reagent tube for a detecting apparatus according to claim 1, wherein the gun head (1) includes a channel portion (102) and a connecting portion (103), the liquid outlet (101) is formed on the channel portion (102), the connecting portion (103) is provided on an outer peripheral side of the channel portion (102) and forms an internal thread on an inner peripheral wall, and an external thread for mating with the internal thread is formed on the tube body (2).

6. The reagent tube for a detecting apparatus according to claim 5, wherein a housing chamber (208) for housing the liquid is formed inside the tube body (2), and an end of the passage portion (102) remote from the liquid outlet (101) extends into the housing chamber (208) and is in close contact with an inner peripheral wall of the housing chamber (208).

7. The reagent tube for a detecting apparatus according to claim 6, wherein a first guide surface (1031) is formed on an outer peripheral wall of the channel portion (102) near one end of the housing chamber (208), and the first guide surface (1031) is in an inverted circular truncated cone shape.

8. The reagent tube for a detecting apparatus according to claim 5, wherein a second limiting step (207) for limiting the movement of the connecting portion (103) is further formed on the outer peripheral wall of the tube body (2).

9. Reagent vessel for a detection apparatus according to any of the claims 1-8, characterized in that the reagent vessel further comprises a protective cover (4) detachably arranged on the gun head (1).

10. A detection device, characterized in that it comprises a reagent tube for a detection device according to any one of claims 1-9.