CN220027056U

CN220027056U - Reagent tube for detection device and detection device

Info

Publication number: CN220027056U
Application number: CN202320902003.9U
Authority: CN
Inventors: 解亚平; 匡超; 曾波; 朱滔; 戴立忠
Original assignee: Hunan Yuanjing Intelligent Manufacturing Technology Co ltd
Current assignee: Hunan Yuanjing Intelligent Manufacturing Technology Co ltd
Priority date: 2023-04-20
Filing date: 2023-04-20
Publication date: 2023-11-17
Anticipated expiration: 2033-04-20

Abstract

The utility model discloses a reagent tube for a detection device and the detection device, the reagent tube comprises: the pipe body comprises a containing part and a first connecting part arranged at one end of the containing part, a containing cavity for containing liquid is formed in the containing part, and a piston cavity communicated with the containing cavity is formed in the first connecting part; the gun head is detachably arranged at one end of the accommodating part far away from the first connecting part and is provided with a liquid outlet for discharging liquid; the piston assembly comprises a piston rod and a limiting cylinder connected with the piston rod, part of the piston rod is movably arranged in the piston cavity, and a limiting end face used for resisting the side end face of the accommodating part facing the limiting cylinder is formed on the limiting cylinder. This a reagent pipe and check out test set for check out test set simple structure need not the extrusion dynamics of control piston rod when the check out test set uses it to carry out the pipettor and can realize quantitative pipetting, can guarantee the accuracy of quantitative pipetting better, has promoted the accuracy of pipetting.

Description

Reagent tube for detection device and detection device

Technical Field

The utility model relates to the technical field of detection instruments, in particular to a reagent tube for detection equipment and the detection equipment.

Background

In performing biological or medical tests, a test person typically uses a reagent tube to store, transfer a reagent or liquid sample, and drop the reagent or liquid sample into the interior of the reagent to be tested for testing analysis. The detection personnel most need carry out quantitative pipetting through the mode of artificial judgement when using reagent pipe among the prior art to carry out reagent or sample transfer, like prior art CN204365334U discloses a scale pipette, including pipette main part and sharp mouth, the top of pipette main part has conical pipette mouth, conical pipette mouth opening part aperture is greater than the aperture of pipette main part, pipette main part surface is provided with the scale, the design has the liquid reserve pipe in the middle of the pipette main part, install the piston switch on the pipette main part, during the pipetting, operating personnel observe whether reagent or liquid sample flush with the scale in the pipette main part through the human eye and realize quantitative pipetting. However, when a large amount of quantitative pipetting is performed, fatigue is determined manually, so that the amount of pipetting of a reagent or a liquid sample is deviated, and the reagent or the liquid sample is not easy to perceive, so that the subsequent detection result is inaccurate.

Disclosure of Invention

The utility model aims to provide a reagent tube for detection equipment and detection equipment, which have simple structures and can play a role in improving quantitative pipetting accuracy.

In order to achieve the above object, a first aspect of the present utility model provides a reagent tube for a detection apparatus, the reagent tube comprising:

the pipe body comprises a containing part and a first connecting part arranged at one end of the containing part, a containing cavity for containing liquid is formed in the containing part, and a piston cavity communicated with the containing cavity is formed in the first connecting part;

the gun head is detachably arranged at one end of the accommodating part far away from the first connecting part and is provided with a liquid outlet for discharging liquid;

the piston assembly comprises a piston rod and a limiting cylinder connected with the piston rod, part of the piston rod is movably arranged in the piston cavity, and a limiting end face used for resisting the side end face of the accommodating part facing the limiting cylinder is formed on the limiting cylinder.

In an embodiment of the utility model, the piston assembly further comprises a seal fitted over the piston rod and located in the piston chamber.

In an embodiment of the utility model, the piston assembly further comprises an elastic restoring member for restoring the piston rod, one end of the elastic restoring member is connected with the tube body, and the other end of the elastic restoring member is connected with the end of the piston rod away from the accommodating cavity.

In the embodiment of the utility model, the first limiting step is formed on the outer peripheral wall of the first connecting part, the limiting cylinder is arranged on the outer peripheral side of the piston rod and the first connecting part, and the limiting block part used for resisting the first limiting step is formed on the inner peripheral wall of the limiting cylinder.

In an embodiment of the present utility model, the gun head includes a passage portion on which the liquid outlet is formed, and a second connection portion provided on an outer peripheral side of the passage portion and forming an internal thread on an inner peripheral wall, and the receiving portion is formed with an external thread for mating with the internal thread.

In the embodiment of the utility model, one end of the channel part, which is far away from the liquid outlet, extends into the accommodating cavity and is clung to the inner peripheral wall of the accommodating cavity.

In an embodiment of the utility model, a guide rib for guiding the flow of the liquid is further provided on the inner peripheral wall of the receiving portion.

In an embodiment of the present utility model, a second limiting step for limiting movement of the second connection portion is further formed on the outer peripheral wall of the accommodating portion.

In an embodiment of the utility model, the reagent vessel further comprises a cover detachably arranged on the gun head.

A second aspect of the utility model provides a detection device comprising a reagent tube as described above for a detection device.

According to the technical scheme, the reagent tube comprises a tube body, a gun head and a piston assembly, wherein the tube body comprises a containing part and a first connecting part, the gun head is detachably arranged at one end of the containing part far away from the first connecting part and is provided with a liquid outlet for discharging liquid, the piston assembly comprises a piston rod and a limiting cylinder connected with the piston rod, part of the piston rod is movably arranged in a piston cavity, the limiting cylinder is provided with a limiting end face used for resisting the side end face of the containing part, which faces the limiting cylinder, the piston rod is pressed, and the piston rod moves towards the direction of the containing cavity, so that the liquid can be discharged outwards through the liquid outlet; after the limiting cylinder moves by a preset distance, the limiting end face of the limiting cylinder can resist the side end face of the accommodating part, which faces the limiting cylinder, no matter how large force is applied to the piston rod, the piston rod cannot be enabled to move continuously, therefore, the piston rod can only move by the preset distance, liquid inside the reagent tube can only extrude out by the preset volume, and the quantitative pipetting function of the reagent tube is realized. This reagent pipe simple structure, the detection personnel need not the extrusion dynamics of control piston rod when using it to carry out the pipettor and can realize quantitative pipettor, need not artificial judgement, also can not produce the pipetting deviation because of tired operation, can guarantee the accuracy of quantitative pipettor better, has promoted the accuracy of pipettor.

Drawings

The accompanying drawings are included to provide a further understanding of embodiments of the utility model and are incorporated in and constitute a part of this specification, illustrate embodiments of the utility model and together with the description serve to explain, without limitation, the embodiments of the utility model. In the drawings:

FIG. 1 is a schematic cross-sectional view of a reagent tube according to an embodiment of the present utility model;

FIG. 2 is a schematic view showing the overall structure of a reagent tube according to an embodiment of the present utility model;

FIG. 3 is a schematic view of a limiting cylinder according to an embodiment of the present utility model;

FIG. 4 is a schematic view of a gun head according to an embodiment of the present utility model;

fig. 5 is a schematic cross-sectional view of a gun head according to an embodiment of the present utility model.

Description of the reference numerals

1-a tube body; 101-a housing; 1011-receiving cavity; 1012-a second limiting step; 102-a first connection; 1021-a piston chamber; 1022-first limit step; 2-gun heads; 201-a liquid outlet; 202-a channel portion; 2021-pipetting channel; 2022-first channel segment; 2023-a second channel segment; 2024-third channel segment; 2025-a first tapered transition section; 2026-a second conical transition section; 203-a second connection; 2031-guide surfaces; 3-piston assembly; 301-a piston rod; 302, a limiting cylinder; 3021-limiting end surfaces; 3022-stopper portions; 303-a seal; 304-an elastic restoring member; 4-a cover; 5-cotton swab.

Detailed Description

The following describes specific embodiments of the present utility model in detail with reference to the drawings. It should be understood that the detailed description and specific examples, while indicating and illustrating the utility model, are not intended to limit the utility model.

An embodiment of the present utility model provides a novel reagent tube for a detection apparatus, which is suitable for a detection apparatus, as shown in fig. 1-2, and includes:

the pipe body 1 includes a housing portion 101 and a first connection portion 102 provided at one end of the housing portion 101, a housing chamber 1011 for housing a liquid is formed inside the housing portion 101, and a piston chamber 1021 communicating with the housing chamber 1011 is formed inside the first connection portion 102;

a gun head 2 detachably provided at an end of the accommodating portion 101 remote from the first connecting portion 102 and having a liquid outlet 201 for discharging liquid;

the piston assembly 3 includes a piston rod 301 and a stopper cylinder 302 connected to the piston rod 301, a part of the piston rod 301 being movably disposed in the piston chamber 1021, the stopper cylinder 302 being formed with a stopper end surface 3021 for abutting on a side end surface of the accommodation portion 101 facing the stopper cylinder 302.

Specifically, a pipetting channel 2021 for communicating with the accommodating cavity 1011 is formed inside the gun head 2, and the liquid outlet 201 is located at one end of the pipetting channel 2021 away from the accommodating cavity 1011; a columnar chamber having a variable volume is formed between an end of the piston rod 301 adjacent to the accommodation chamber 1011 and an inner peripheral wall of the piston chamber 1021, and a liquid (in this embodiment, a reagent) is stored in the accommodation chamber 1011 in advance. Before performing pipetting, a detector firstly uses the cotton swab 5 to sample nucleic acid (the nucleic acid is a sample in this embodiment), then screws the gun head 2, places the cotton swab 5 in the accommodating cavity 1011, then screws the gun head 2 and shakes the whole reagent tube, so that the nucleic acid in the cotton swab 5 and the liquid in the accommodating cavity 1011 are fully mixed, and after the nucleic acid and the liquid in the accommodating cavity 1011 are fully mixed, the whole reagent tube is inverted. Because the gun head 2 can discharge the redundant air in the reagent tube (the reagent tube in the embodiment is composed of the columnar cavity, the accommodating cavity 1011 and the pipetting channel 2021) through the liquid outlet 201 in the screwing process, after the gun head 2 is screwed, the air pressure outside the reagent tube and the pressure inside the reagent tube reach balance, and the inside of the reagent tube forms a relative sealing state, so that even if the reagent tube is integrally inverted, the liquid in the reagent tube cannot leak out through the liquid outlet 201.

After the whole reagent tube is inverted, a detector presses down the piston rod 301 (in this embodiment, an electric push rod or a hydraulic push rod or other devices can be used to press the piston rod 301), the piston rod 301 moves towards the direction of the accommodating cavity 1011, the volume of the columnar cavity is reduced, the space inside the reagent tube is reduced, the air pressure inside the reagent tube is increased, and the liquid inside the reagent tube can be discharged outwards through the liquid outlet 201. When the piston rod 301 moves, the limiting cylinder 302 is driven to move together, and the moving strokes of the limiting cylinder 302 and the limiting cylinder are consistent, after the limiting cylinder 302 moves by a preset distance, the limiting end face 3021 of the limiting cylinder can resist the side end face of the accommodating part 101 facing the limiting cylinder 302, no matter how much force is applied to the piston rod 301 by a detector, the piston rod 301 cannot move continuously, so that the piston rod 301 can only move by the preset distance, that is, the space inside the reagent tube can only be reduced by the preset size, and accordingly, the liquid inside the reagent tube can only be extruded outwards by the preset volume, thereby realizing the quantitative pipetting function of the reagent tube. The reagent tube is simple in structure, quantitative pipetting can be achieved without controlling extrusion force of the piston rod 301 when a detector uses the reagent tube to perform pipetting, manual judgment is not needed, pipetting deviation cannot be generated due to fatigue operation, accuracy of quantitative pipetting can be well guaranteed, and accuracy of pipetting is improved.

In one embodiment of the utility model, the piston assembly 3 further comprises a seal 303 fitted over the piston rod 301 and located in the piston chamber 1021. Specifically, the sealing member 303 in this embodiment is a sealing ring, which is used to enhance the sealing performance inside the reagent tube, so as to avoid the situation of liquid leakage or air leakage, and facilitate further improving the accuracy of pipetting.

In another embodiment of the present utility model, an annular sealing portion is formed on the outer circumferential wall of the piston rod 301, and an interference fit is formed between the annular sealing portion and the inner circumferential wall of the piston chamber 1021, thereby ensuring the sealing performance of the inside of the reagent tube.

In one embodiment of the present utility model, the piston assembly 3 further includes an elastic restoring member 304 for restoring the piston rod 301, one end of the elastic restoring member 304 is connected to the tube body 1, and the other end of the elastic restoring member 304 is connected to the end of the piston rod 301 remote from the accommodating chamber 1011. Specifically, the elastic restoring member 304 in this embodiment is a spring, one end of the spring is connected to the first limiting step 1022 on the tube body 1, the other end of the spring is connected to one end of the piston rod 301 away from the accommodating cavity 1011, and when the detecting person presses the piston rod 301, the spring is compressed; after the inspector stops pressing the piston rod 301, the spring restores the elasticity and drives the piston rod 301 to return to the initial position, so that the inspector can press the piston rod next time.

In one embodiment of the present utility model, a first limiting step 1022 is formed on the outer peripheral wall of the first connecting portion 102, a limiting cylinder 302 is disposed on the outer peripheral side of the piston rod 301 and the first connecting portion 102, and a limiting block 3022 for abutting on the first limiting step 1022 is formed on the inner peripheral wall of the limiting cylinder 302 as shown in fig. 3. Specifically, the first limiting step 1022 is annular, when the detecting personnel presses the piston rod 301, the piston rod 301 drives the limiting cylinder 302 to move together, and the movement directions are consistent, at this time, the limiting block part 3022 moves in a direction away from the first limiting step 1022; when the piston rod 301 and the limiting cylinder 302 are reset under the action of the spring, the limiting block part 3022 moves towards the direction close to the first limiting step 1022, after the side end face of the limiting block part 3022 is attached to the side end face of the first limiting step 1022, the limiting block part 3022 stops moving under the blocking action of the first limiting step 1022, accordingly, the limiting cylinder 302 and the piston rod 301 also stop moving, the moving distance of the limiting cylinder 302 and the piston rod 301 during reset is limited, the moving distance of the piston rod 301 is prevented from being excessively long and separated from the piston cavity 1021, and the structural stability and the reliability of the moving device are improved.

In one embodiment of the present utility model, the gun head 2 includes a passage portion 202 and a second connection portion 203, the liquid outlet 201 is formed on the passage portion 202, the second connection portion 203 is provided on an outer peripheral side of the passage portion 202 and forms an internal thread on an inner peripheral wall, and the receiving portion 101 is formed with an external thread for mating with the internal thread. Specifically, as shown in fig. 4 to 5, a pipetting channel 2021 is formed on the channel portion 202, and the liquid in the tube body 1 can flow out from the liquid outlet 201 after flowing through the pipetting channel 2021; the second connection part 203 and the accommodating part 101 are detachably connected through screw thread fit, so that a inspector can unscrew the gun head 2 and put the cotton swab 5 with nucleic acid into the tube body 1, and then can screw the gun head 2 so as to invert the whole reagent tube.

In one embodiment of the present utility model, one end of the channel portion 202 away from the liquid outlet 201 extends into the accommodating cavity 1011 and is tightly attached to the inner peripheral wall of the accommodating cavity 1011, specifically, an annular cavity is formed between the channel portion 202 and the second connecting portion 203 in this embodiment, and an interference fit is formed between one end of the channel portion 202 away from the liquid outlet 201 and the accommodating cavity 1011, which is beneficial to further enhancing the sealing performance inside the mobile device, so that the liquid can flow from the accommodating cavity 1011 directly into the pipetting channel 2021 without entering the annular cavity.

In one embodiment of the present utility model, the pipetting channel 2021 comprises a first channel section 2022, a second channel section 2023 and a third channel section 2024 which are sequentially connected back and forth, the liquid outlet 201 is located on the third channel section 2024, and a first conical transition section 2025 is further arranged between the first channel section 2022 and the second channel section 2023 so as to promote the smoothness of the flow of the liquid when the liquid enters the second channel section 2023 from the first channel section 2022; a second conical transition section 2026 is also provided between the second and third channel sections 2023, 2024 to promote smoothness of flow of the liquid from the second channel section 2023 into the third channel section 2024. Further, the inner diameter of the first passage section 2022 is in the range of 7mm to 8mm, and the difference between the inner diameter of the accommodation chamber 1011 near one end of the first passage section 2022 and the inner diameter of the first passage section 2022 is in the range of 2mm to 3mm, which is arranged so that the liquid can flow into the first passage section 2022 from the accommodation chamber 1011 quickly; the inner diameter of the third channel section 2024 ranges from 0.4mm to 0.6mm, the length of the third channel section 2024 ranges from 5mm to 6mm, and the inner diameter of the numerical range enables the third channel section 2024 to be slender, so that the accuracy of the reagent tube in liquid outlet is further improved, the pressure balance between the inside of the reagent tube and the outside of the reagent tube is maintained after the gun head 2 is screwed, and unexpected leakage of liquid in the reagent tube is avoided; the difference between the inner diameter of the second channel section 2023 and the inner diameter of the third channel section 2024 is in the range of 1mm-2mm, the difference between the inner diameter of the first channel section 2022 and the inner diameter of the second channel section 2023 is in the range of 5mm-6mm, and the arrangement is such that the second channel section 2023 becomes a transition section between the first channel section 2022 and the third channel section 2024, which plays a role in movement transition for the liquid.

In one embodiment of the present utility model, an inclined guiding surface 2031 is formed on the outer peripheral wall of the channel portion 202 near one end of the accommodating cavity 1011, the guiding surface 2031 is in an inverted truncated cone shape, and when the gun head 2 is mounted, the arrangement is convenient for the small outer diameter portion of the channel portion 202 to extend into the accommodating cavity 1011 first, so that the convenience in mounting the gun head 2 is enhanced.

In an embodiment of the present utility model, a second limiting step 1012 for limiting movement of the second connection portion 203 is further formed on the outer peripheral wall of the accommodating portion 101, the second limiting step 1012 is in a ring shape, and after the threaded fit between the second connection portion 203 and the accommodating portion 101 reaches a preset length, due to the blocking of the second limiting step 1012, a inspector cannot continue to screw up the gun head 2, so that movement limiting of the second connection portion 203 is achieved, connection tightness is ensured, and meanwhile operation time of the inspector is saved.

In one embodiment of the present utility model, the inner peripheral wall of the accommodating portion 101 is further provided with a guiding rib (not shown in the figure) for guiding the flow of the liquid, and the setting direction of the guiding rib is consistent with the axial direction of the accommodating cavity 1011, so that the adhesion between the mixed liquid (the substance after mixing the liquid and the nucleic acid) in the accommodating cavity 1011 and the inner peripheral wall of the accommodating cavity 1011 can be reduced, the mixed liquid can be smoothly led out from the accommodating cavity 1011 with limited inner space when the reagent tube is integrally inverted, the smoothness of the mixed liquid flowing from the accommodating cavity 1011 to the pipetting channel 2021 is enhanced, the mixed liquid is prevented from being retained on the inner peripheral wall of the accommodating cavity 1011, and the accuracy of quantitative pipetting is further improved.

In one embodiment of the present utility model, the reagent tube further comprises a cover 4 detachably disposed on the gun head 2, specifically, the cover 4 is used for protecting the gun head 2 and also preventing external impurities from entering the internal polluted liquid of the mobile device through the liquid outlet 201; the outer peripheral wall of the second channel section 2023 is provided with an external thread, and the inner peripheral wall of the cover body 4 is provided with an internal thread matched with the external thread, so that the detachable connection between the cover body 4 and the gun head 2 is realized.

In another embodiment of the present utility model, a novel detection device is provided, which includes the reagent tube for the detection device in the above embodiment.

The preferred embodiments of the present utility model have been described in detail above with reference to the accompanying drawings, but the present utility model is not limited thereto. Within the scope of the technical idea of the utility model, a plurality of simple variants of the technical proposal of the utility model can be carried out, comprising that each specific technical feature is combined in any suitable way, and in order to avoid unnecessary repetition, the utility model does not need to be additionally described for various possible combinations. Such simple variations and combinations are likewise to be regarded as being within the scope of the present disclosure.

In the present utility model, unless explicitly specified and limited otherwise, the terms "mounted," "connected," "secured," and the like are to be construed broadly, and may be, for example, fixedly connected, detachably connected, or integrally formed; may be mechanically connected, may be electrically connected or may be in communication with each other; either directly or indirectly, through intermediaries, or both, may be in communication with each other or in interaction with each other, unless expressly defined otherwise. The specific meaning of the above terms in the present utility model can be understood by those of ordinary skill in the art according to the specific circumstances.

In the present utility model, unless expressly stated or limited otherwise, a first feature "up" or "down" a second feature may be the first and second features in direct contact, or the first and second features in indirect contact via an intervening medium. Moreover, a first feature being "above," "over" and "on" a second feature may be a first feature being directly above or obliquely above the second feature, or simply indicating that the first feature is level higher than the second feature. The first feature being "under", "below" and "beneath" the second feature may be the first feature being directly under or obliquely below the second feature, or simply indicating that the first feature is less level than the second feature.

While embodiments of the present utility model have been shown and described above, it will be understood that the above embodiments are illustrative and not to be construed as limiting the utility model, and that variations, modifications, alternatives and variations may be made to the above embodiments by one of ordinary skill in the art within the scope of the utility model.

Claims

1. A reagent tube for a detection apparatus, the reagent tube comprising:

a tube body (1) comprising a containing part (101) and a first connecting part (102) arranged at one end of the containing part (101), wherein a containing cavity (1011) for containing liquid is formed inside the containing part (101), and a piston cavity (1021) communicated with the containing cavity (1011) is formed inside the first connecting part (102);

a gun head (2) detachably arranged at one end of the accommodating part (101) far away from the first connecting part (102) and provided with a liquid outlet (201) for discharging the liquid;

the piston assembly (3) comprises a piston rod (301) and a limiting cylinder (302) connected with the piston rod (301), part of the piston rod (301) is movably arranged in the piston cavity (1021), and the limiting cylinder (302) is provided with a limiting end face (3021) used for resisting the side end face of the accommodating part (101) facing the limiting cylinder (302).

2. A reagent tube for a detection apparatus according to claim 1, wherein the piston assembly (3) further comprises a seal (303) which fits over the piston rod (301) and is located in the piston chamber (1021).

3. A reagent tube for a detection apparatus according to claim 1, wherein the piston assembly (3) further comprises an elastic restoring member (304) for restoring the piston rod (301), one end of the elastic restoring member (304) is connected to the tube body (1), and the other end of the elastic restoring member (304) is connected to the end of the piston rod (301) remote from the accommodation chamber (1011).

4. The reagent tube for a detecting apparatus according to claim 1, wherein a first stopper step (1022) is formed on an outer peripheral wall of the first connecting portion (102), the stopper cylinder (302) is provided on an outer peripheral side of the piston rod (301) and the first connecting portion (102), and a stopper portion (3022) for abutting on the first stopper step (1022) is formed on an inner peripheral wall of the stopper cylinder (302).

5. The reagent tube for a detecting apparatus according to claim 4, wherein the gun head (2) includes a channel portion (202) and a second connecting portion (203), the liquid outlet (201) is formed on the channel portion (202), the second connecting portion (203) is provided on an outer peripheral side of the channel portion (202) and forms an internal thread on an inner peripheral wall, and the housing portion (101) is formed with an external thread for mating with the internal thread.

6. The reagent tube for a detecting apparatus according to claim 5, wherein an end of the channel portion (202) remote from the liquid outlet (201) extends into the housing chamber (1011) and is in close contact with an inner peripheral wall of the housing chamber (1011).

7. The reagent tube for a detecting apparatus according to claim 5, wherein a second limiting step (1012) for limiting movement of the second connecting portion (203) is further formed on an outer peripheral wall of the accommodating portion (101).

8. Reagent tube for a detection device according to claim 1, characterized in that the inner peripheral wall of the receptacle (101) is further provided with guide ribs for guiding the flow of the liquid.

9. A reagent vessel for a detection apparatus according to any one of claims 1 to 8, further comprising a cover (4) detachably provided on the lance tip (2).

10. A detection device, characterized in that it comprises a reagent tube for a detection device according to any one of claims 1-9.