CN220143668U

CN220143668U - Magnetic separation equipment

Info

Publication number: CN220143668U
Application number: CN202321585022.XU
Authority: CN
Inventors: 王萍; 王子贵; 卢龙; 赵巧辉; 李桂林; 付光宇; 吴学炜; 杨增利
Original assignee: Zhengzhou Immuno Biotech Co Ltd
Current assignee: Zhengzhou Immuno Biotech Co Ltd
Priority date: 2023-06-20
Filing date: 2023-06-20
Publication date: 2023-12-08
Anticipated expiration: 2033-06-20

Abstract

The utility model discloses magnetic separation equipment, which comprises at least two brackets used for surrounding the periphery of a reaction kettle; any support is provided with magnetic pieces, and all the magnetic pieces are distributed to surround the reaction kettle when all the supports are surrounded on the periphery of the reaction kettle. The magnetic separation equipment utilizes a plurality of magnetic pieces to disperse and surround the reaction kettle, provides a magnetic field for materials in the reaction kettle, and can be applied to magnetic separation operation of magnetic nano biological materials; the bracket is also used for quickly adjusting the relative positions of all the magnetic pieces, so that all the magnetic pieces can quickly surround the reaction kettle and separate from the reaction kettle, and meanwhile, the bracket can also adjust the relative positions of all the magnetic pieces when surrounding the reaction kettle, so that all the magnetic pieces are suitable for the reaction kettles with different sizes. In addition, the magnetic separation equipment can improve magnetic flux by increasing the number of magnetic pieces, the single magnetic piece is large in size and easy to process, and all the magnetic pieces are arranged on different supports, so that the influence of the increase of the number of the magnetic pieces on the processing cost and the operation difficulty of the magnetic separation equipment is weak and even negligible.

Description

Magnetic separation equipment

Technical Field

The utility model relates to the technical field of magnetic separation equipment, in particular to magnetic separation equipment.

Background

Among various biomedical nanomaterials, magnetic nanomaterials are widely applied to clinical diagnosis and biomedical research due to their unique magnetic properties, such as chemiluminescent magnetic beads and nucleic acid extraction magnetic beads applied to the field of diagnosis, purified magnetic beads applied to the field of biotechnology, cell separation magnetic beads and the like. In accordance with the wide application of magnetic nano biological materials, magnetic separation technology is an important content in the field of biomedical materials.

For the biomedical material field, the magnetic separation technology often refers to separating the magnetic nano-biological material from a specific solution in a reaction kettle by utilizing the magnetic sensitivity of elements or components under the action of an external magnetic field, so as to achieve the effect of solid-liquid separation.

The existing magnetic response equipment for realizing magnetic separation is provided with a ring magnet, a reaction kettle is sleeved on the ring magnet, a magnetic nano biological material in the reaction kettle can be adsorbed and positioned on the inner wall of the reaction kettle by utilizing a magnetic field generated by the ring magnet, and then clear liquid capable of freely flowing in the reaction kettle is pumped out, so that solid separation is realized. However, the reaction vessel is bulky, it is difficult to provide a ring magnet capable of completely wrapping the reaction vessel, and for this reason, the magnetic response device needs to reasonably control the amount of materials in the reaction vessel, so that the whole materials are gradually separated in small amounts and multiple times, which results in complicated operation, time and effort for the separation operation. In addition, the ring magnet is usually fixedly installed, so when the reaction kettle is sleeved by the ring magnet, the reaction kettle is generally required to be lifted and inserted into the ring magnet, and a spot is visible in operation difficulty and operation burden.

Disclosure of Invention

The utility model aims to provide magnetic separation equipment, which can simplify the magnetic separation operation of materials in a reaction kettle and is convenient for improving magnetic flux on the premise of reasonably controlling cost and operation difficulty, thereby improving magnetic separation efficiency.

In order to achieve the above object, the present utility model provides a magnetic separation device comprising at least two brackets for surrounding the circumference of a reaction vessel; any support is provided with magnetic pieces, and all the magnetic pieces are distributed to surround the reaction kettle when all the supports are surrounded on the periphery of the reaction kettle.

In some embodiments, the device further comprises a base station provided with a slideway; all the brackets are connected with the slide way in a sliding way.

In some embodiments, a positioning lock is provided between either bracket and the slideway.

In some embodiments, a locating lock is provided between adjacent brackets.

In some embodiments, the abutment is provided on the cart.

In some embodiments, any one of the brackets is provided with a curved plate, and all the curved plates are spliced into a cylinder when all the brackets are surrounded on the periphery of the reaction kettle; the inner wall of any curved plate is provided with a plurality of magnetic pieces.

In some embodiments, the magnetic member is embodied as a magnet block embedded in the curved plate; the inner wall of any curved plate is uniformly embedded with a plurality of magnet blocks.

In some embodiments, the abutting faces of adjacent curved panels are provided with bumper strips.

In some embodiments, the bracket includes a curved guard and legs; the curved surface guard board is attached to the curved surface plate, and the supporting legs are provided with rollers; the size of any curved surface guard plate is smaller than that of the corresponding curved surface guard plate.

In some embodiments, the number of all brackets and the number of all curved plates are two; any bracket is connected with a semi-cylindrical curved plate.

Compared with the background art, the magnetic separation device provided by the utility model comprises at least two brackets which are used for being surrounded on the periphery of the reaction kettle; wherein, any one of the brackets is provided with a magnetic part, and when all the brackets are surrounded on the periphery of the reaction kettle, all the magnetic parts are dispersed around the reaction kettle and surround the reaction kettle.

The magnetic separation equipment utilizes the magnetic pieces to separate the magnetic materials and the non-magnetic materials in the reaction kettle, and utilizes the support to quickly adjust the relative positions of all the magnetic pieces, so that all the magnetic pieces quickly surround the reaction kettle and are separated from the reaction kettle, and the support can also adjust the relative positions of all the magnetic pieces when surrounding the reaction kettle, so that all the magnetic pieces are applicable to the reaction kettles with different sizes.

Therefore, the magnetic separation equipment can conveniently and efficiently realize the magnetic separation operation of the magnetic nano biological material. In addition, the magnetic separation device can increase the magnetic flux by increasing the number of magnetic pieces; wherein the size of a single magnetic piece is easy to process, so that the influence of the number of the magnetic pieces on the processing cost is weak, all the magnetic pieces are respectively arranged on a plurality of brackets, the influence of the number of the magnetic pieces on the operation difficulty of the magnetic separation equipment is little, in short, the magnetic separation device can increase the number of magnetic pieces on the premise of reasonably controlling the cost and the operation difficulty, so that the magnetic flux of the magnetic separation device is improved, and the magnetic separation efficiency is improved.

Drawings

In order to more clearly illustrate the embodiments of the present utility model or the technical solutions in the prior art, the drawings that are required to be used in the embodiments or the description of the prior art will be briefly described below, and it is obvious that the drawings in the following description are only embodiments of the present utility model, and that other drawings can be obtained according to the provided drawings without inventive effort for a person skilled in the art.

FIG. 1 is a schematic diagram of a magnetic separation device according to an embodiment of the present utility model;

FIG. 2 is a top view of FIG. 1;

FIG. 3 is a cross-sectional view of a magnetic separation device along the direction A-A provided by an embodiment of the present utility model;

fig. 4 is a left side view of fig. 1.

Wherein, 1-support, 11-curved surface backplate, 12-landing leg, 13-gyro wheel, 2-magnetic part, 3-base station, 31-slide, 4-crashproof strip, 5-shallow, 6-curved surface board.

Detailed Description

The following description of the embodiments of the present utility model will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present utility model, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the utility model without making any inventive effort, are intended to be within the scope of the utility model.

The present utility model will be further described in detail below with reference to the drawings and detailed description for the purpose of enabling those skilled in the art to better understand the aspects of the present utility model.

Referring to fig. 1 to 4, fig. 1 is a schematic structural diagram of a magnetic separation device according to an embodiment of the present utility model; FIG. 2 is a top view of FIG. 1; FIG. 3 is a cross-sectional view of a magnetic separation device along the direction A-A provided by an embodiment of the present utility model; fig. 4 is a left side view of fig. 1.

Referring to fig. 1, the present utility model provides a magnetic separation device, which comprises more than two brackets 1 for surrounding the circumference of a reaction kettle, and a magnetic member 2 disposed on any one of the brackets 1; when all the brackets 1 are surrounded on the periphery of the reaction kettle, all the magnetic pieces 2 are dispersed to surround the reaction kettle.

All magnetic pieces 2 are dispersed and surrounded on the reaction kettle means that all magnetic pieces 2 are dispersed and distributed around the reaction kettle and surround the reaction kettle, for example, a common reaction kettle is cylindrical, all magnetic pieces 2 can be uniformly dispersed along the same cylindrical curved surface when all magnetic pieces are directly surrounded on the periphery of the reaction kettle, the cylindrical curved surface is coaxially sleeved on the reaction kettle, and the diameter of the cylindrical curved surface is slightly larger than that of the reaction kettle, so that each magnetic piece 2 positioned on the cylindrical curved surface is closely adjacent to the reaction kettle. When all the magnetic pieces 2 are uniformly dispersed along the cylindrical curved surface, the distances between the magnetic pieces 2 and the reaction kettle are equal, and of course, the equal distances between the magnetic pieces 2 and the reaction kettle are not necessarily required by the magnetic separation device, in other words, the distances between the magnetic pieces 2 and the reaction kettle in the magnetic separation device may be unequal.

The magnetic separation device forms a magnetic field around the reaction vessel using all the magnetic pieces 2. When materials containing magnetic materials are placed in the reaction kettle, the magnetic field can provide driving force for the magnetic materials, so that the magnetic materials are gathered on the inner wall of the reaction kettle, and the magnetic materials and the non-magnetic materials are separated. After the separation process is finished, the nonmagnetic materials in the reaction kettle can be removed independently, for example, clear liquid in the reaction kettle is pumped out through a pipeline, and only solid magnetic materials are left in the reaction kettle, so that the purpose of solid-liquid separation is realized.

In view of the relatively large size of the reactor, the magnetic separation device generally surrounds the reactor with a large number of magnetic members 2, that is, any one of the holders 1 is generally provided with a plurality of magnetic members 2, and all the magnetic members 2 of the same holder 1 are positioned on the holder 1 in a dispersed manner.

The positioning of the magnetic element 2 on the support 1 may refer to that the magnetic element 2 is directly mounted on the support 1 or that the magnetic element 2 is indirectly mounted on the support 1, and no matter what kind of connection mode is adopted, a specific relative positional relationship exists between the magnetic element 2 and the support 1 all the time, so that the magnetic element 2 can be gathered along with the folding of the plurality of supports 1 around the reaction kettle or can be scattered along with the scattering of the plurality of supports 1 around the reaction kettle.

The magnetic separation equipment separates magnetic materials and non-magnetic materials in the reaction kettle by using the magnetic pieces 2, and utilizes the bracket 1 to quickly adjust the relative positions of all the magnetic pieces 2, so that all the magnetic pieces 2 quickly surround the reaction kettle and are separated from the reaction kettle, and of course, the bracket 1 can also adjust the relative positions of all the magnetic pieces 2 when surrounding the reaction kettle, so that all the magnetic pieces 2 are applicable to the reaction kettles with different sizes. Therefore, the magnetic separation equipment can reduce the operation difficulty of separating the magnetic materials in the reaction kettle and is applicable to reaction kettles of different types. Therefore, the magnetic separation equipment is convenient to use, more magnetic pieces 2 can be adopted to disperse and surround the reaction kettle, the magnetic flux is improved, and the operation effect of magnetic separation operation is improved.

The magnetic separation device provided by the utility model is further described below with reference to the accompanying drawings and embodiments.

As shown in fig. 1 and 2, in some embodiments, the magnetic separation device further comprises a base station 3; the base 3 is provided with the slide way 31, and all supports 1 are all in sliding connection with the slide way, that is to say, all supports 1 can slide on the base 3, and the slide way of base 3 can retrain the slide track of support 1, makes things convenient for operating personnel to surround all supports 1 in reation kettle's week side fast accurately.

When the support 1 is slidably mounted on the slide way, a positioning lock for locking and unlocking the support 1 and the slide way can be arranged between the support 1 and the slide way, and when all the supports 1 are surrounded on the periphery of the reaction kettle, all the supports 1 can be locked and positioned on the base station 3, so that all the magnetic pieces 2 arranged on all the supports 1 can be reliably dispersed and surrounded on the reaction kettle for a long time.

In addition, when the brackets 1 are slidably mounted on the slide, the brackets 1 and 1 may be provided with positioning locks for locking and unlocking both, in other words, positioning locks are provided between adjacent brackets 1, and the relative positional relationship of all the brackets 1 can be locked when all the brackets 1 are surrounded on the circumference side of the reaction vessel.

As for the specific shape and configuration of the above-mentioned positioning lock, the present disclosure is not limited in particular, and various locks with locking and unlocking functions in the prior art may be referred to.

As mentioned above, the reactor is bulky and heavy, and if it is necessary to operate different reactors with the magnetic separation device, it is more reasonable to move the magnetic separation device than to move the reactor, and for this purpose, the magnetic separation device further comprises a cart 5, and the base 3 is provided on the cart 5, and obviously, all the supports 1 are also indirectly mounted on the cart 5 through the base 3. When the magnetic separation device is used, an operator can move the magnetic separation device with the cart 5 gently and quickly.

The cart 5 can be provided with handrails, so that an operator can conveniently move the cart 5 to a target position at will through the handrails. When the magnetic materials in the reaction kettle are required to be subjected to solid-liquid separation, the magnetic separation equipment can be pushed to the vicinity of the target reaction kettle, and after the relative position relationship between the target reaction kettle and the magnetic separation equipment is adjusted, the support 1 of the magnetic separation equipment is driven to move, so that all the supports 1 enclose the reaction kettle.

Usually, the reaction kettle is suspended on the ground mostly through the mounting frame, so that when the relative position relationship between the target reaction kettle and the magnetic separation device is achieved, the magnetic separation device can be moved to one side of the mounting frame, and then the reaction kettle is lifted and pushed to be transferred onto the magnetic separation device.

In addition, for the purpose of reducing the work load, if no object is left right above the reaction kettle, the magnetic separation device can hoist all the brackets 1, so that the lower ends of all the brackets 1 are suspended, and the rest structures of the magnetic separation device are enabled to avoid the space right below all the brackets 1, so that an operator can directly move the magnetic separation device without moving the reaction kettle, and the reaction kettle is surrounded by all the brackets 1.

Referring to fig. 1 and 3, in some other embodiments of the present utility model, the magnetic separation device further includes a curved plate 6 disposed on the support 1, and the magnetic members 2 are located on the curved plate 6 in a dispersed manner, that is, the magnetic members 2 are indirectly mounted on the support 1 through the curved plate 6. All supports 1 of the magnetic separation device are provided with curved plates 6, and when all supports 1 are surrounded on the periphery of the reaction kettle, all curved plates 6 are spliced into a cylinder, and the cylinder is sleeved with the reaction kettle. As for the concrete shape of the barrel formed by the splicing of all the curved plates 6, it is possible to flexibly set according to the shape configuration of the reaction vessel, for example, when the reaction vessel is cylindrical, all the curved plates 6 may be spliced into a cylinder, and when the reaction vessel is rugby, all the curved plates 6 may be spliced into a rugby-shaped barrel.

In the above embodiment, the magnetic member 2 is provided on the inner wall of the curved plate 6, for example, a plurality of magnetic members 2 are fixedly mounted on the inner wall of one curved plate 6, and these magnetic members 2 may be adhered to the inner wall of the curved plate 6 or may be embedded in the curved plate 6 and exposed to the inner side of the curved plate 6. Typically, the magnet 2 is specifically configured as a magnet block; a plurality of magnet blocks are uniformly embedded on the inner wall of any one of the curved plates 6.

Referring to fig. 2, in some embodiments, a bumper strip 4 is disposed between two adjacent curved plates 6, the bumper strip 4 is disposed on a butt surface of the adjacent curved surfaces, and when two adjacent curved plates 6 are spliced together, the two curved plates 6 squeeze the bumper strip 4 therebetween, so as to avoid the two curved plates 6 from being impacted too much. In general, the bumper strip 4 is made of rubber-containing materials, has high elasticity, can buffer and absorb energy when the butt joint surfaces of the adjacent curved plates 6 collide, avoids the curved plates 6 from being damaged, and also avoids accidentally injuring operators.

Referring to fig. 1 and 4, in some embodiments, the bracket 1 includes a leg 12 and a curved shield 11 connected; the supporting leg 12 is provided with a roller 13, and can move rapidly and loosely by virtue of the roller 13; the curved surface guard plate 11 is attached to the curved surface plate 6, and in general, the size of the curved surface guard plate 11 is smaller than the corresponding size of the curved surface plate 6, which is beneficial to reducing the processing difficulty and processing cost of the curved surface guard plate 11. The supporting legs 12 may be disposed below the curved guard plate 11, and are used for supporting the curved guard plate 11 upwards, and further supporting the curved plate 6 upwards and the magnetic member 2 disposed on the curved plate 6.

In the above embodiment, any one of the support legs 12 may be provided with a plurality of rollers 13, for example, one support leg 12 is provided with four rollers 13, the four rollers 13 can rotate in the same direction, and the four rollers 13 are not collinear, so that free movement of the support leg 12 can be realized, and tilting of the support leg 12 can be avoided.

In the embodiments mentioned herein, the number of both the brackets 1 and the curved plates 6 in the magnetic separation device may be two, that is, the two curved plates 6 are spliced into a cylinder when the two brackets 1 are surrounded on the circumference of the reaction kettle, and the plurality of magnetic pieces 2 provided on the two curved plates 6 are dispersed on the circumference of the reaction kettle and surround the reaction kettle. The two curved plates 6 may be half-cylindrical plates, and the two half-cylindrical curved plates 6 are spliced into a cylinder.

The magnetic separation device provided by the utility model is described in detail above. The principles and embodiments of the present utility model have been described herein with reference to specific examples, the description of which is intended only to facilitate an understanding of the method of the present utility model and its core ideas. It should be noted that it will be apparent to those skilled in the art that various modifications and adaptations of the utility model can be made without departing from the principles of the utility model and these modifications and adaptations are intended to be within the scope of the utility model as defined in the following claims.

Claims

1. A magnetic separation device, characterized by comprising at least two brackets (1) for surrounding the circumference of a reaction kettle; any support (1) is provided with magnetic pieces (2), and all the magnetic pieces (2) are distributed to surround the reaction kettle when all the supports (1) surround the periphery of the reaction kettle.

2. A magnetic separation device according to claim 1, further comprising a base (3) provided with a slide (31); all the brackets (1) are connected with the slideway (31) in a sliding way.

3. A magnetic separation device according to claim 2, characterized in that a positioning lock is provided between any of the brackets (1) and the slideway (31).

4. A magnetic separation device according to claim 2, characterized in that a positioning lock is provided between adjacent brackets (1).

5. A magnetic separation device according to claim 2, characterized in that the base station (3) is provided in a trolley (5).

6. A magnetic separation device according to any one of claims 1 to 5, characterized in that any one of the brackets (1) is provided with curved plates (6), all of the curved plates (6) being spliced into a cylinder when all of the brackets (1) are surrounded on the circumference side of the reaction vessel; the inner wall of any curved plate (6) is provided with a plurality of magnetic pieces (2).

7. The magnetic separation device according to claim 6, characterized in that the magnetic element (2) is embodied as a magnet block embedded in the curved plate (6); the inner wall of any curved plate (6) is uniformly embedded with a plurality of magnet blocks.

8. A magnetic separation device according to claim 6, characterized in that the abutting surface of adjacent curved plates (6) is provided with a bumper strip (4).

9. A magnetic separation device according to claim 6, characterized in that the bracket (1) comprises a curved shield (11) and legs (12); the curved surface guard plate (11) is attached to the curved surface plate (6), and the supporting legs (12) are provided with rollers (13); the size of any curved guard plate (11) is smaller than the corresponding curved plate (6).

10. A magnetic separation device according to claim 6, characterized in that the number of all the holders (1) and the number of all the curved plates (6) are two; any bracket (1) is connected with a semi-cylindrical curved plate (6).