CN219984093U - Doxofylline refining and purifying device - Google Patents
Doxofylline refining and purifying device Download PDFInfo
- Publication number
- CN219984093U CN219984093U CN202321601154.7U CN202321601154U CN219984093U CN 219984093 U CN219984093 U CN 219984093U CN 202321601154 U CN202321601154 U CN 202321601154U CN 219984093 U CN219984093 U CN 219984093U
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- CN
- China
- Prior art keywords
- doxofylline
- box
- filter screen
- purifying
- purifying box
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 229960004483 doxofylline Drugs 0.000 title claims abstract description 62
- HWXIGFIVGWUZAO-UHFFFAOYSA-N doxofylline Chemical compound C1=2C(=O)N(C)C(=O)N(C)C=2N=CN1CC1OCCO1 HWXIGFIVGWUZAO-UHFFFAOYSA-N 0.000 title claims abstract description 62
- 238000007670 refining Methods 0.000 title claims abstract description 13
- 238000010438 heat treatment Methods 0.000 claims abstract description 52
- 238000000746 purification Methods 0.000 claims abstract description 38
- 230000007246 mechanism Effects 0.000 claims description 21
- 238000003756 stirring Methods 0.000 claims description 19
- 239000000463 material Substances 0.000 claims description 15
- 238000007789 sealing Methods 0.000 claims description 15
- 239000002994 raw material Substances 0.000 abstract description 43
- 239000012535 impurity Substances 0.000 abstract description 6
- ZFXYFBGIUFBOJW-UHFFFAOYSA-N theophylline Chemical compound O=C1N(C)C(=O)N(C)C2=C1NC=N2 ZFXYFBGIUFBOJW-UHFFFAOYSA-N 0.000 description 38
- 229960000278 theophylline Drugs 0.000 description 19
- 238000002347 injection Methods 0.000 description 16
- 239000007924 injection Substances 0.000 description 16
- 238000009833 condensation Methods 0.000 description 5
- 230000005494 condensation Effects 0.000 description 5
- 230000000903 blocking effect Effects 0.000 description 2
- 238000004821 distillation Methods 0.000 description 2
- 230000000857 drug effect Effects 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- 206010067484 Adverse reaction Diseases 0.000 description 1
- 206010002383 Angina Pectoris Diseases 0.000 description 1
- 208000024172 Cardiovascular disease Diseases 0.000 description 1
- 206010019233 Headaches Diseases 0.000 description 1
- 206010020772 Hypertension Diseases 0.000 description 1
- 206010028813 Nausea Diseases 0.000 description 1
- 206010033557 Palpitations Diseases 0.000 description 1
- 230000006838 adverse reaction Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 210000004204 blood vessel Anatomy 0.000 description 1
- 230000037396 body weight Effects 0.000 description 1
- 210000000748 cardiovascular system Anatomy 0.000 description 1
- 229940000032 cardiovascular system drug Drugs 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 230000000916 dilatatory effect Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 231100000869 headache Toxicity 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 230000004130 lipolysis Effects 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 230000002107 myocardial effect Effects 0.000 description 1
- 208000010125 myocardial infarction Diseases 0.000 description 1
- 230000008693 nausea Effects 0.000 description 1
- 230000003647 oxidation Effects 0.000 description 1
- 238000007254 oxidation reaction Methods 0.000 description 1
- 230000036284 oxygen consumption Effects 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- -1 purifying box 1 Chemical compound 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
Landscapes
- Vaporization, Distillation, Condensation, Sublimation, And Cold Traps (AREA)
Abstract
The utility model discloses a doxofylline refining and purifying device, and relates to the technical field of doxofylline purification. Including purification case, bin outlet, first heating block and hot-blast case, the feeding subassembly is installed to the top of purification case, and the internally mounted of purification case has the filter screen, the bin outlet is installed to the below of purification case, and installs the control valve on the bin outlet, first heating block and second heating block are installed respectively to the interior bottom surface left and right sides of purification case, and the left side of first heating block installs the conducting strip, the condensing box is installed on the right side of purification case, and the hot-blast case is installed in the left side of purification case. This refined purification device of doxofylline is provided with guide chamber and feed inlet, opens sealed lid, drops into the doxofylline raw materials through the guide chamber, and then the even whereabouts of feed inlet below the doxofylline raw materials through the guide chamber prevents that the impurity in the doxofylline raw materials from piling up in the fixed position of filter screen in below, accelerates the jam of filter screen.
Description
Technical Field
The utility model relates to the technical field of doxofylline purification, in particular to a doxofylline refining and purifying device.
Background
Doxofylline is a cardiovascular system drug that can improve the function and performance of the cardiovascular system by dilating blood vessels and reducing myocardial oxygen consumption. It is commonly used for treating cardiovascular diseases such as angina pectoris, myocardial infarction, hypertension, etc., and doxofylline can also increase fat oxidation and metabolism, promote lipolysis, thereby helping to lose weight and control body weight. Doxofylline is widely used in the medical and health care fields, but the use method and the dosage need to be paid attention to, and adverse reactions such as headache, nausea, palpitation and the like are avoided. The instructions should be read carefully before use and used under the direction of a doctor or professional.
In the process of preparing doxofylline, the doxofylline raw material needs to be purified in order to ensure the quality and the drug effect of the doxofylline.
The utility model provides a purification equipment of doxofylline injection, through installing first heating pipe on the inner wall of heating jar, install the second heating pipe on the inside support column of heating jar, with the inside of raw materials injection heating jar through annotating the liquid mouth when carrying out distillation, the inside and the outside of stoste can be heated simultaneously to first heating pipe on the inner wall and the second heating pipe on the support column, the homogeneity of heating and the quality of injection purification when having guaranteed the distillation, the steam of production can get into in the cooling tank through steam conduit and cool off, can realize the purification, the purification device of current doxofylline injection can be because of inside and outside heating inhomogeneous when carrying out the heating, lead to influencing its purification quality when distilling, the problem of reduction of the doxofylline injection drug effect of extraction. However, the device has certain defects;
when the doxofylline injection raw material is put into, the filter mechanism is not arranged in the heating tank, and impurities contained in the doxofylline injection raw material cannot be filtered, so that the doxofylline injection raw material is dissolved in the doxofylline injection in the heating process, and the purification precision of the doxofylline injection is reduced.
We have therefore proposed a doxofylline refining apparatus to solve the problems set out above.
Disclosure of Invention
The utility model aims to provide a doxofylline refining and purifying device, which aims to solve the problems that when the doxofylline injection raw material is put into the existing doxofylline injection purifying equipment in the market, which is proposed by the background technology, a filtering mechanism is not arranged in a heating tank, and impurities contained in the doxofylline injection raw material cannot be filtered, so that the doxofylline injection raw material is dissolved in the doxofylline injection in the heating process, and the purification precision of the doxofylline injection is reduced.
In order to achieve the above purpose, the present utility model provides the following technical solutions: the utility model provides a refined purification device of doxofylline, includes purification case, bin outlet, first heating piece and hot-blast case, feed assembly is installed to the top of purification case, and the internally mounted of purification case has the filter screen, and servo motor is installed on the right side of purification case moreover, the bin outlet is installed to the below of purification case, and installs the control valve on the bin outlet, first heating piece and second heating piece are installed respectively to the interior bottom surface left and right sides of purification case, and the conducting strip is installed in the left side of first heating piece, the cooler bin is installed on the right side of purification case, and the hot-blast case is installed in the left side of purification case, and the air-blower is installed to the top of hot-blast case moreover.
Preferably, the feeding assembly comprises a sealing cover, a material guiding cavity and a feeding port, wherein the sealing cover is positioned above the feeding assembly, a detachable structural design is arranged between the sealing cover and the feeding assembly, the material guiding cavity is arranged below the sealing cover and is in a herringbone structural design, and a plurality of feeding ports are arranged on the lower surface of the material guiding cavity at equal intervals.
By adopting the structural design, the sealing cover is opened, the doxofylline raw material is put into the guide cavity, then the doxofylline raw material uniformly falls down through the feed inlet below the guide cavity, impurities in the doxofylline raw material are prevented from being accumulated at the fixed position of the filter screen below, and the blocking of the filter screen is accelerated.
Preferably, the filter screen is detachable structural design, and the filter screen is located under the feeding subassembly.
By adopting the structural design, when more impurities are accumulated on the filter screen, the box door of the purification box is opened, and the filter screen is detached for cleaning or replacement.
Preferably, the left side of the servo motor is provided with a stirring mechanism through an output shaft, the stirring mechanism is positioned in the purifying box, and the stirring mechanism is positioned above the first heating block and the second heating block.
By adopting the structural design, the servo motor is started, the servo motor drives the stirring mechanism to rotate through the output shaft, and then the stirring mechanism stirs the filtered doxofylline raw materials in the purifying box, so that the doxofylline raw materials are heated by the first heating block and the second heating block more uniformly.
Preferably, the condensing box is connected with the purifying box through a condensing pipe, the connecting position of the condensing pipe and the purifying box is positioned below the filter screen, and the condensing box is positioned above the servo motor.
By adopting the structural design, after the doxofylline raw material is heated, the purified doxofylline is collected through the condensing pipe, so that the doxofylline enters the condensing box through the condensing pipe, and the purification of the doxofylline is completed.
Preferably, the blower is connected with the hot air box through a first air inlet pipe, the upper end of the heat conducting fin is positioned in the hot air box, the connection position of the heat conducting fin and the hot air box is in a sealing structure design, and the hot air box is connected with the purifying box through a second air inlet pipe.
By adopting the structural design, the blower is started, the blower supplies air into the hot air box through the first air inlet pipe, the heat conducting fin conducts heat through the first heating block, the temperature in the hot air box is increased, and then the first air inlet pipe conveys hot air into the purifying box through the second air inlet pipe, so that the upper and lower positions of the doxofylline raw materials in the purifying box can be heated, and the doxofylline raw materials are heated more uniformly.
Compared with the prior art, the utility model has the beneficial effects that: this doxofylline refining purification device:
1. the multi-rope theophylline filter screen is provided with a material guide cavity and a material inlet, a sealing cover is opened, the multi-rope theophylline raw material is input through the material guide cavity, then the multi-rope theophylline raw material uniformly falls through the material inlet below the material guide cavity, impurities in the multi-rope theophylline raw material are prevented from accumulating at a fixed position of a filter screen below, and the blocking of the filter screen is accelerated;
2. be provided with conducting strip and air-blower, start servo motor and air-blower, servo motor passes through the output shaft and drives rabbling mechanism rotation, then rabbling mechanism stirs the multi-rope theophylline raw materials after the bottom filters in the purification case, make multi-rope theophylline raw materials more even by first heating block and second heating block heating, the air-blower is through first air-supply line to hot bellows in the air inlet, the conducting strip carries out heat conduction through first heating block simultaneously, make the temperature in the hot bellows rise, and the inside of hot-blast through second air-supply line is carried to the purification case to back first air-supply line, thereby the multi-rope theophylline raw materials upper and lower positions in the messenger purification case all can be heated, thereby it is more even that multi-rope theophylline raw materials are heated.
Drawings
FIG. 1 is a schematic view of the main section structure of the present utility model;
FIG. 2 is a schematic diagram of a front view structure of the present utility model;
FIG. 3 is a schematic view of the feed assembly of the present utility model;
FIG. 4 is a schematic view showing the internal structure of the hot air box according to the present utility model.
In the figure: 1. a purifying box; 2. a feed assembly; 201. sealing cover; 202. a material guiding cavity; 203. a feed inlet; 3. a filter screen; 4. a servo motor; 5. a stirring mechanism; 6. a discharge port; 7. a control valve; 8. a first heating block; 9. a second heating block; 10. a heat conductive sheet; 11. a condensing box; 12. a condensing tube; 13. a hot air box; 14. a blower; 15. a first air inlet pipe; 16. and a second air inlet pipe.
Detailed Description
The following description of the embodiments of the present utility model will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present utility model, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the utility model without making any inventive effort, are intended to be within the scope of the utility model.
Referring to fig. 1-4, the present utility model provides a technical solution: the utility model provides a refined purification device of doxofylline, including purifying box 1, feeding subassembly 2, sealed lid 201, guide chamber 202, feed inlet 203, filter screen 3, servo motor 4, rabbling mechanism 5, bin outlet 6, control valve 7, first heating block 8, second heating block 9, heat conducting strip 10, the condensation tank 11, condenser pipe 12, hot-blast case 13, air-blower 14, first air-supply line 15 and second air-supply line 16, feeding subassembly 2 is installed to the top of purifying box 1, feeding subassembly 2 includes sealed lid 201, guide chamber 202 and feed inlet 203, sealed lid 201 is located the top of feeding subassembly 2, and be detachable structural design between sealed lid 201 and the feeding subassembly 2, the below of sealed lid 201 is provided with guide chamber 202, guide chamber 202 is "people" font structural design, and the lower surface equidistance of guide chamber 202 installs a plurality of feed inlet 203, open sealed lid 201, throw into the doxofylline raw materials through guide chamber 202, then the even whereabouts of feed inlet 203 below the guide chamber 202, prevent that the doxofylline raw materials from falling down, prevent that the filter screen 3 from being detached in the filter screen 3 is directly under the filter screen 3 is more and the filter screen 3 is stacked when the filter screen 3 is directly under the filter screen 3 is dismantled to the filter screen 3 is fixed to the filter screen 3 when the filter screen is opened, the filter screen 3 is more in the filter screen 3 is stacked up the filter screen 3, can be removed when the filter screen 3 is more than the filter screen 3 is installed to be removed and the filter screen 1.
A servo motor 4 is arranged on the right side of the purifying box 1, a stirring mechanism 5 is arranged on the left side of the servo motor 4 through an output shaft, the stirring mechanism 5 is positioned in the purifying box 1, the stirring mechanism 5 is positioned above a first heating block 8 and a second heating block 9, the servo motor 4 is started, the stirring mechanism 5 is driven to rotate through the output shaft by the servo motor 4, then the stirring mechanism 5 stirs the doxofylline raw material filtered in the purifying box 1, the doxofylline raw material is heated by the first heating block 8 and the second heating block 9 more uniformly, a discharge opening 6 is arranged below the purifying box 1, a control valve 7 is arranged on the discharge opening 6, a first heating block 8 and a second heating block 9 are respectively arranged on the left side and the right side of the inner bottom surface of the purifying box 1, a heat conducting fin 10 is arranged on the left side of the first heating block 8, a condensing box 11 is arranged on the right side of the purifying box 1, the condensing box 11 is connected with the purifying box 1 through a condensing pipe 12, the connecting position of the condensing pipe 12 and the purifying box 1 is positioned below the filter screen 3, the condensing box 11 is positioned above the servo motor 4, after the doxofylline raw material is heated, the condensing pipe 12 is used for collecting the purified doxofylline, so that the doxofylline enters the condensing box 11 through the condensing pipe 12 to finish the purification of the doxofylline, a hot air box 13 is arranged at the left side of the purifying box 1, a blower 14 is arranged above the hot air box 13, the blower 14 is connected with the hot air box 13 through a first air inlet pipe 15, the upper end of the heat conducting fin 10 is positioned inside the hot air box 13, the connecting position of the heat conducting fin 10 and the hot air box 13 is in a sealing structure design, the hot air box 13 is connected with the purifying box 1 through a second air inlet pipe 16, the blower 14 is started, the air blower 14 is used for feeding air into the hot air box 13 through the first air inlet pipe 15, meanwhile, the heat conducting fin 10 conducts heat through the first heating block 8, so that the temperature in the hot air box 13 is increased, and then the first air inlet pipe 15 is used for conveying hot air into the purification box 1 through the second air inlet pipe 16, so that the upper and lower positions of the doxofylline raw materials in the purification box 1 can be heated, and the doxofylline raw materials are heated more uniformly.
Working principle: when the multi-rope theophylline refining and purifying device is used, firstly, the servo motor 4 and the blower 14 are started, the sealing cover 201 is opened, the multi-rope theophylline raw material is thrown into the hot air box 13 through the material guide cavity 202, then the multi-rope theophylline raw material uniformly falls down through the feeding hole 203 below the material guide cavity 202, the multi-rope theophylline raw material falls into the inner bottom of the purifying box 1 after being filtered through the filter screen 3, the servo motor 4 drives the stirring mechanism 5 to rotate through the output shaft, then the stirring mechanism 5 stirs the multi-rope theophylline raw material filtered in the inner bottom of the purifying box 1, the multi-rope theophylline raw material is enabled to be more uniformly heated by the first heating block 8 and the second heating block 9, the blower 14 is used for feeding the multi-rope theophylline raw material into the hot air box 13 through the first air inlet pipe 15, meanwhile, the heat conducting sheet 10 conducts heat through the first heating block 8, the temperature in the hot air box 13 is increased, and then the first air inlet pipe 15 is used for conveying hot air into the purifying box 1 through the second air inlet pipe 16, so that the multi-rope theophylline raw material in the purifying box 1 can be heated up and down, the multi-rope theophylline raw material filtered in the purifying box 1 is enabled to be heated, then the multi-rope theophylline raw material is enabled to be heated uniformly, and condensed, and the multi-rope theophylline raw material is purified through the condensation pipe 12 is enabled to enter the condensation pipe after being purified through the condensation pipe, and finally, the condensation pipe 11 is cooled. Thereby completing a series of works. What is not described in detail in this specification is prior art known to those skilled in the art.
Although the present utility model has been described with reference to the foregoing embodiments, it will be apparent to those skilled in the art that modifications may be made to the embodiments described, or equivalents may be substituted for elements thereof, and any modifications, equivalents, improvements and changes may be made without departing from the spirit and principles of the present utility model.
Claims (6)
1. The utility model provides a refined purification device of doxofylline, includes purification case (1), bin outlet (6), first heating piece (8) and hot-blast case (13), its characterized in that: feeding subassembly (2) are installed to the top of purifying box (1), and the internally mounted of purifying box (1) has filter screen (3), servo motor (4) are installed on the right side of purifying box (1) moreover, bin outlet (6) are installed to the below of purifying box (1), and install control valve (7) on bin outlet (6), first heating block (8) and second heating block (9) are installed respectively in the interior bottom surface left and right sides of purifying box (1), and heat conducting strip (10) are installed in the left side of first heating block (8), condensing tank (11) are installed on the right side of purifying box (1), and hot bellows (13) are installed in the left side of purifying box (1), and air-blower (14) are installed to the top of hot bellows (13).
2. The doxofylline refining and purifying apparatus as set forth in claim 1, wherein: the feeding assembly (2) comprises a sealing cover (201), a material guiding cavity (202) and a feeding hole (203), wherein the sealing cover (201) is located above the feeding assembly (2), a detachable structural design is arranged between the sealing cover (201) and the feeding assembly (2), the material guiding cavity (202) is arranged below the sealing cover (201), the material guiding cavity (202) is of a herringbone structural design, and a plurality of feeding holes (203) are formed in the lower surface of the material guiding cavity (202) at equal intervals.
3. The doxofylline refining and purifying apparatus as set forth in claim 1, wherein: the filter screen (3) is of a detachable structural design, and the filter screen (3) is located under the feeding component (2).
4. The doxofylline refining and purifying apparatus as set forth in claim 1, wherein: the left side of servo motor (4) is installed through the output shaft and is stirred mechanism (5), and stirring mechanism (5) are located the inside of purifying box (1), and stirring mechanism (5) are located the top of first heating piece (8) and second heating piece (9).
5. The doxofylline refining and purifying apparatus as set forth in claim 1, wherein: the condensing box (11) is connected with the purifying box (1) through a condensing pipe (12), the connecting position of the condensing pipe (12) and the purifying box (1) is located below the filter screen (3), and the condensing box (11) is located above the servo motor (4).
6. The doxofylline refining and purifying apparatus as set forth in claim 1, wherein: the air blower (14) is connected with the hot air box (13) through a first air inlet pipe (15), the upper end of the heat conducting fin (10) is positioned in the hot air box (13), the connection position of the heat conducting fin (10) and the hot air box (13) is in a sealing structure design, and the hot air box (13) is connected with the purifying box (1) through a second air inlet pipe (16).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202321601154.7U CN219984093U (en) | 2023-06-21 | 2023-06-21 | Doxofylline refining and purifying device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202321601154.7U CN219984093U (en) | 2023-06-21 | 2023-06-21 | Doxofylline refining and purifying device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN219984093U true CN219984093U (en) | 2023-11-10 |
Family
ID=88614115
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202321601154.7U Active CN219984093U (en) | 2023-06-21 | 2023-06-21 | Doxofylline refining and purifying device |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN219984093U (en) |
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2023
- 2023-06-21 CN CN202321601154.7U patent/CN219984093U/en active Active
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