CN219976936U - Drying oven suitable for concentrated protein - Google Patents

Drying oven suitable for concentrated protein Download PDF

Info

Publication number
CN219976936U
CN219976936U CN202322712176.7U CN202322712176U CN219976936U CN 219976936 U CN219976936 U CN 219976936U CN 202322712176 U CN202322712176 U CN 202322712176U CN 219976936 U CN219976936 U CN 219976936U
Authority
CN
China
Prior art keywords
drying
placing
drawer
air
drying box
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN202322712176.7U
Other languages
Chinese (zh)
Inventor
魏彦辉
全敬宇
王永明
马玉岭
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beijing Solarbio Technology Co ltd
Original Assignee
Beijing Solarbio Technology Co ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beijing Solarbio Technology Co ltd filed Critical Beijing Solarbio Technology Co ltd
Priority to CN202322712176.7U priority Critical patent/CN219976936U/en
Application granted granted Critical
Publication of CN219976936U publication Critical patent/CN219976936U/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Abstract

The utility model relates to the technical field of general physical laboratory equipment, in particular to a drying oven suitable for concentrating protein, which comprises the following components: the drying box comprises a drying box body, wherein a first placing area suitable for placing a dialysis bag and a second placing area suitable for placing a drying agent are arranged in the drying box body, and the first placing area is communicated with the second placing area; the drying cabinet body is equipped with air inlet structure and air-out structure, the air inlet structure with the first district of placing with the district is all linked together to the second, the air-out structure with the first district of placing with the district is all linked together to the second. The drying box suitable for the concentrated protein provided by the utility model is used for carrying out water absorption drying treatment on the protein liquid to be concentrated by improving the gas exchange speed and adopting a drying mode of compounding an isolated drying agent, and realizing rapid concentration treatment on the premise of ensuring the cleanliness of the concentrated protein. Can prevent the concentrated protein from being polluted and denatured so as to ensure the precision of subsequent scientific research.

Description

Drying oven suitable for concentrated protein
Technical Field
The utility model relates to the technical field of general physical laboratory equipment, in particular to a drying box suitable for concentrating protein.
Background
Protein samples are subjected to a series of separation extractions and chromatographies, which result in the sample being diluted, and many analyses and studies require high concentration or high purity samples, so concentration of the protein samples is critical. The protein concentration technology belongs to the field of concentration technology of biological macromolecules, and aims at eliminating water, ions and other small molecular matters from protein solution by means of physical or chemical process to raise the protein concentration in unit volume.
In the prior art, protein concentration comprises a dialysis bag concentration method, a freeze drying concentration method, a blow drying concentration method, an ultrafiltration membrane concentration method, a gel concentration method and the like. Wherein, the most widely applied is a dialysis bag concentration method, the protein solution to be concentrated is put into a dialysis bag, and a polymer (such as polyethylene glycol or sucrose, etc.) with a molecular weight of 6000-12000 is scattered outside the dialysis bag. This has the advantage that the equilibration time is short. However, some protein concentration using high molecular weight polymers may result in protein denaturation due to various factors such as improper operation or improper time control.
Accordingly, a drying oven suitable for concentrating proteins is needed to solve the above problems.
Disclosure of Invention
The utility model provides a drying box suitable for concentrating proteins, which is used for solving the defect that a dialysis bag concentration method in the prior art can cause protein denaturation, and realizing rapid protein concentration on the premise of ensuring that the protein cannot be denatured.
The utility model provides a drying oven suitable for concentrating protein, comprising: the drying box comprises a drying box body, wherein a first placing area suitable for placing a dialysis bag and a second placing area suitable for placing a drying agent are arranged in the drying box body, and the first placing area is communicated with the second placing area;
the drying cabinet body is equipped with air inlet structure and air-out structure, the air inlet structure with the first district of placing with the district is all linked together to the second, the air-out structure with the first district of placing with the district is all linked together to the second.
According to the drying box suitable for concentrating proteins, the air inlet structure comprises at least one first air inlet arranged on the drying box body, and the air outlet structure comprises at least one first air outlet arranged on the drying box body.
According to the drying box suitable for the concentrated protein, the first air inlet is provided with the air inlet device, and the first air outlet is provided with the air outlet device.
According to the drying box suitable for concentrating proteins, the first drawer and the second drawer are arranged in the drying box body, the first placing area is arranged in the first drawer, and the second placing area is arranged in the second drawer.
According to the drying box suitable for concentrating proteins, the first side wall of the first drawer is provided with the second air inlet, and the second side wall of the first drawer is provided with the second air outlet.
According to the drying box suitable for concentrating proteins, the first drawer is located above the second drawer, and the bottom of the first drawer is provided with the opening.
According to the drying box suitable for concentrating proteins, the first drawer is provided with the placing frame, and the placing frame is provided with the ventilation opening;
a placing tray is arranged in the second drawer.
The drying oven suitable for concentrating proteins provided by the utility model further comprises a temperature control module suitable for controlling the temperature inside the drying oven body.
The drying oven suitable for concentrating protein provided by the utility model further comprises a humidity control module suitable for controlling the humidity inside the drying oven body.
The drying oven suitable for concentrating protein, provided by the utility model, further comprises a control module, wherein the control module comprises a control screen, and the control screen is arranged on the drying oven body.
When the drying box suitable for concentrating protein is used, the dialysis bag filled with protein liquid to be concentrated is placed in the first placement area, the drying agent is placed in the second placement area, the air inlet structure is utilized to ventilate the interior of the drying box body, the gas exchange speed in the drying box body is improved, namely, the protein liquid to be concentrated is subjected to water absorption drying treatment in a drying mode of improving the gas exchange speed and combining the isolated drying agent, and the rapid concentration treatment is realized on the premise of ensuring the cleanliness of the concentrated protein. Can prevent the denaturation of the concentrated protein and avoid pollution so as to ensure the precision of subsequent scientific research.
Additional advantages, objects, and features of the utility model will be set forth in part in the description which follows and in part will become apparent to those having ordinary skill in the art upon examination of the following or may be learned from practice of the utility model. The objects and other advantages of the utility model may be realized and obtained by means of the instrumentalities and combinations particularly pointed out in the specification.
Drawings
In order to more clearly illustrate the utility model or the technical solutions of the prior art, the following description will briefly explain the drawings used in the embodiments or the description of the prior art, and it is obvious that the drawings in the following description are some embodiments of the utility model, and other drawings can be obtained according to the drawings without inventive effort for a person skilled in the art.
FIG. 1 is one of the isometric views of a drying oven suitable for concentrating proteins provided in an embodiment of the present utility model;
FIG. 2 is a second perspective view of a drying oven suitable for concentrating proteins according to an embodiment of the present utility model;
FIG. 3 is a front view of a drying oven suitable for concentrating proteins according to an embodiment of the present utility model;
FIG. 4 is a top view of a drying oven suitable for concentrating proteins provided in an embodiment of the present utility model;
FIG. 5 is a right side view of a drying oven suitable for concentrating proteins provided in an embodiment of the present utility model;
FIG. 6 is a left side view of a drying oven suitable for concentrating proteins provided in an embodiment of the present utility model;
fig. 7 is a schematic view of a first drawer in a drying oven suitable for concentrating proteins according to an embodiment of the present utility model.
Reference numerals:
1. a drying box body; 101. a first air inlet; 102. a first air outlet; 2. a first drawer; 201. a second air inlet; 202. a second air outlet; 3. a second drawer; 4. an air inlet device; 5. an air outlet device; 6. a placing rack; 7. and (5) controlling a screen.
Detailed Description
For the purpose of making the objects, technical solutions and advantages of the present utility model more apparent, the technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings, and it is apparent that the described embodiments are some embodiments of the present utility model, not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the utility model without making any inventive effort, are intended to be within the scope of the utility model.
In describing embodiments of the present utility model, it should be noted that, unless explicitly stated and limited otherwise, the terms "coupled," "coupled," and "connected" should be construed broadly, and may be either a fixed connection, a removable connection, or an integral connection, for example; can be mechanically or electrically connected; can be directly connected or indirectly connected through an intermediate medium. The specific meaning of the above terms in embodiments of the present utility model will be understood in detail by those of ordinary skill in the art.
In the description of the present specification, a description referring to terms "one embodiment," "some embodiments," "examples," "specific examples," or "some examples," etc., means that a particular feature, structure, material, or characteristic described in connection with the embodiment or example is included in at least one embodiment or example of the embodiments of the present utility model. In this specification, schematic representations of the above terms are not necessarily directed to the same embodiment or example. Furthermore, the particular features, structures, materials, or characteristics described may be combined in any suitable manner in any one or more embodiments or examples. Furthermore, the different embodiments or examples described in this specification and the features of the different embodiments or examples may be combined and combined by those skilled in the art without contradiction.
The drying oven suitable for concentrating proteins provided by the present utility model is described below with reference to fig. 1 to 7.
As shown in fig. 1 to 6, the present utility model provides a drying oven suitable for concentrating proteins, comprising: the drying box comprises a drying box body 1, wherein a first placing area suitable for placing a dialysis bag and a second placing area suitable for placing a drying agent are arranged in the drying box body 1, and the first placing area is communicated with the second placing area; the drying cabinet body 1 is equipped with air inlet structure and air-out structure, and air inlet structure and first district and the second of placing are placed the district and all are communicated, and the air-out structure is placed the district with first and is placed the district with the second and all are communicated.
Specifically, in this embodiment, the drying oven body 1 is a rectangular box structure, and the first placement area and the second placement area are both disposed inside the drying oven body 1.
The air inlet structure is used for introducing air into the drying box body 1, and the air outlet structure is used for discharging air in the drying box body 1 to the outside, so that the air exchange speed around the dialysis bag is increased. Wherein, the air inlet structure can adopt the form of external air-supply line, also can adopt such as air supply arrangement such as fan, send into drying cabinet body 1 inside with external environment's air, and the air-out structure can adopt negative pressure structure of induced drafting, also can directly set up the air outlet through the corresponding position at drying cabinet body 1, discharges the inside gas of drying cabinet body 1 to the external world. Under the effect of air inlet structure and air-out structure, can make the first place the district and place the district is located to the second and be in the gas flow environment all the time to promote the concentration rate of waiting concentrated protein liquid in the dialysis bag.
It is contemplated that in some embodiments, to ensure air intake cleanliness of the air intake structure, avoiding contamination of proteins, an air cleaning and sterilizing device may be provided in the air intake structure for cleaning and sterilizing the air.
When the drying box suitable for concentrating protein is used, the dialysis bag filled with protein liquid to be concentrated is placed in the first placement area, the drying agent is placed in the second placement area, the air inlet structure is utilized to ventilate the interior of the drying box body 1, the gas exchange speed in the drying box body 1 is improved, namely, the protein liquid to be concentrated is subjected to water absorption drying treatment in a drying mode of combining the improved gas exchange speed with the isolated drying agent, and the rapid concentration treatment is realized on the premise of ensuring the cleanliness of the concentrated protein. Can prevent the denaturation of the concentrated protein and avoid pollution so as to ensure the precision of the subsequent scientific research.
As shown in fig. 1, 2, 5 and 6, in the embodiment of the present utility model, the air inlet structure includes at least one first air inlet 101 disposed on the drying oven body 1, and the air outlet structure includes at least one first air outlet 102 disposed on the drying oven body 1.
Specifically, in this embodiment, the air inlet structure includes three first air inlets 101 disposed in the drying box body 1, where one first air inlet 101 is located on the right side wall (direction shown in fig. 1) of the drying box body 1, and two first air inlets 101 are located on the top wall of the drying box body 1; the air outlet structure includes a first air outlet 102, and the first air outlet 102 is disposed on a left side wall (a direction shown in fig. 2) of the drying box body 1. When the air inlet device is used, air can be simultaneously introduced into the drying box body 1 through all the first air inlets 101, or air can be introduced into the drying box body 1 through only part of the first air inlets 101.
In some embodiments, the first drawer 2 may also be a drawer without two side panels.
As shown in fig. 4 to 6, in a further embodiment of the present utility model, the first air inlet 101 is provided with an air inlet device 4, and the first air outlet 102 is provided with an air outlet device 5.
Specifically, in this embodiment, the air inlet device 4 is an air inlet fan, the air outlet device 5 is an air outlet fan (exhaust fan), that is, the air inlet fan and the air outlet fan are respectively disposed at the first air inlet 101 and the first air outlet 102, and the air flow in the drying oven body 1 can be driven by the air inlet fan and the air outlet fan to flow, so that the drying oven body 1 is always in the environment of drying air flow in the process of concentrating protein liquid. And the drying cabinet body 1 is convenient for install the setting to air inlet fan and air-out fan, during the installation, only need set up the mounting groove in the corresponding position of drying cabinet body 1 can.
As shown in fig. 3, in the embodiment of the present utility model, a first drawer 2 and a second drawer 3 are provided in the drying oven body 1, the first placement area is provided in the first drawer 2, and the second placement area is provided in the second drawer 3. Through setting up first drawer 2 and second drawer 3, be convenient for place to be equipped with protein solution dialysis bag and drier to concentrate, can also carry out the position pull to first drawer 2 and second drawer 3 simultaneously, be convenient for put the thing operation of getting in the concentration process.
In a further embodiment of the present utility model, as shown in fig. 7, a first side wall of the first drawer 2 is provided with a second air inlet 201, and a second side wall of the first drawer 2 is provided with a second air outlet 202.
Specifically, in this embodiment, the second air inlet 201 is located on the side of the first air inlet 101 (on the right side wall of the drying box body 1), and the second air outlet 202 is located on the side of the first air outlet 102, so that the intake air flows from the second air inlet 201 to the second air outlet 202.
It should be noted that the number of the second air inlets 201 and the second air outlets 202 may be one or multiple, and may be set according to actual requirements and working conditions (such as space layout). The shapes of the second air inlet 201 and the second air outlet 202 may be regular shapes such as a circle or a square, or may be various irregular shapes, which are not particularly limited in the present utility model.
As shown in fig. 1 to 3, in the embodiment of the present utility model, the first drawer 2 is located above the second drawer 3, and the bottom of the first drawer 2 is provided with an opening. The liquid flowing out of the dialysis bag in the concentration process can fall into the second drawer 3 to be absorbed by the drying agent, and the drying agent positioned in the second drawer 3 can be contacted with the air around the dialysis bag to fully absorb the moisture.
Specifically, in this embodiment, a hollowed-out structure is disposed at the bottom of the first drawer 2, and the hollowed-out portion is used as the opening.
In a further embodiment of the utility model, as shown in fig. 7, a rack 6 is provided on the first drawer 2, and the rack 6 is provided with a ventilation opening; a placing tray is arranged in the second drawer 3. By arranging the placing frame 6, the contact area of the dialysis bag air is conveniently increased, and the protein concentration rate is improved. Through setting up the dish of placing, can place the drier in the dish of placing, prevent to cause the pollution to the second drawer.
Specifically, in the present embodiment, the racks 6 are mesh-shaped racks, and the mesh between the mesh-shaped racks serves as the ventilation opening described above. Wherein, the reticular rack can be made of metal or polymer composite materials.
In an embodiment of the utility model, the drying cabinet suitable for concentrating proteins further comprises a temperature control module suitable for controlling the temperature inside the cabinet body 1. Because the protein solution needs to be processed in a low-temperature environment (about 4 ℃) during concentration, the temperature control module is arranged, the temperature of the interior of the drying box is reduced to the low-temperature environment, and protein denaturation is prevented. In addition, after the concentration of the protein solution is finished, the temperature inside the drying box body 1 can be increased by utilizing the temperature control module, and the drying agent is dried, so that the drying box is convenient to recycle.
Specifically, in this embodiment, the temperature control module includes a cooling pipe and a heating pipe, wherein the cooling pipe is disposed in a position of the interior of the drying box body 1 near the first drawer 2 (for example, an inner surface of a top plate of the drying box body 1), and the heating pipe is disposed in a position of the interior of the drying box body 1 near the second drawer 3 (for example, an inner surface of a bottom plate of the drying box body 1 or a bottom plate of a placing tray). When the temperature needs to be reduced, a low-temperature medium is introduced into the refrigeration pipe, and when the temperature needs to be increased, a high-temperature medium is introduced into the heating pipe.
Of course, in some embodiments, the temperature control module may also employ other heating/cooling devices commonly found in the art, such as compression refrigeration, electrical heating, and the like.
In the embodiment of the utility model, the drying oven suitable for concentrating protein further comprises a humidity control module suitable for controlling the humidity inside the drying oven body 1. The humidity inside the drying box body 1 is conveniently controlled, so that the humidity inside the drying box body 1 is always in a range (10% or below) suitable for concentrating the protein solution.
As shown in fig. 4, the drying oven suitable for concentrating protein further comprises a control module, wherein the control module comprises a control screen 7, and the control screen 7 is arranged on the drying oven body 1. Through setting up control panel 7, can show parameters such as the inside temperature of drying cabinet body 1, humidity on control panel 7 in real time, can also send control command to air inlet fan, air-out fan, temperature control module and humidity control module etc. through control panel 7, control start-stop, power and the operating time etc. of corresponding device/module, also can control device carry out the concentration operation according to the mode of predetermineeing.
The working process and principle of the drying oven suitable for concentrating proteins provided by the present utility model are described in detail below with reference to fig. 1 to 7.
During concentration, a protein solution sample is placed into a dialysis bag to be tightly fixed, the first drawer 2 and the second drawer 3 are pulled out, the dialysis bag and the drying agent are respectively placed on the placing frame 7 of the first drawer 2 and in the placing tray in the second drawer 3, and the first drawer 2 and the second drawer 3 are pushed into the drying box body 1. The drying box body 1 is placed in a low-temperature environment or a temperature control module is started to cool the inside of the drying box body 1 to a set temperature, an air inlet structure and an air outlet structure are started to drive air in the drying box body 1 to flow, and when concentration is started, superfluous water molecules of protein solution in a dialysis bag flow out of the dialysis bag through the tiny aperture of the dialysis bag, part of superfluous liquid falls into a drying agent placing drawer of a constant-temperature clean drying box, a small amount of buffer liquid is adhered to the dialysis bag, the air flowing in the drying box is used for drying, and meanwhile, protein in the dialysis bag is kept in a clean filtering space, so that direct contact with the drying agent, related particles, dust and the like is avoided, and the cleanliness of the concentrated protein is guaranteed, so that the precision of subsequent scientific researches is guaranteed.
Finally, it should be noted that: the above embodiments are only for illustrating the technical solution of the present utility model, and are not limiting; although the utility model has been described in detail with reference to the foregoing embodiments, it will be understood by those of ordinary skill in the art that: the technical scheme described in the foregoing embodiments can be modified or some technical features thereof can be replaced by equivalents; such modifications and substitutions do not depart from the spirit and scope of the technical solutions of the embodiments of the present utility model.

Claims (10)

1. A drying cabinet for concentrating protein comprising: the drying box comprises a drying box body, wherein a first placing area suitable for placing a dialysis bag and a second placing area suitable for placing a drying agent are arranged in the drying box body, and the first placing area is communicated with the second placing area;
the drying cabinet body is equipped with air inlet structure and air-out structure, the air inlet structure with the first district of placing with the district is all linked together to the second, the air-out structure with the first district of placing with the district is all linked together to the second.
2. The drying cabinet of claim 1, wherein the air intake structure comprises at least one first air intake disposed in the cabinet body, and the air outlet structure comprises at least one first air outlet disposed in the cabinet body.
3. The drying cabinet according to claim 2, wherein the first air inlet is provided with air inlet means and the first air outlet is provided with air outlet means.
4. The drying cabinet of claim 1, wherein a first drawer and a second drawer are disposed within the cabinet body, the first placement area being disposed in the first drawer, and the second placement area being disposed in the second drawer.
5. The drying cabinet of claim 4, wherein the first side wall of the first drawer is provided with a second air inlet and the second side wall of the first drawer is provided with a second air outlet.
6. The drying cabinet for concentrated protein according to claim 4, wherein the first drawer is located above the second drawer, and a vent is provided at the bottom of the first drawer.
7. The drying cabinet for concentrated protein according to claim 4, wherein a shelf is provided on the first drawer, and an opening is provided on the shelf;
and/or a placing tray is arranged in the second drawer.
8. The drying cabinet for concentrated proteins according to any one of claims 1 to 7, further comprising a temperature control module adapted to control the temperature inside the cabinet body.
9. The drying cabinet for concentrated proteins according to any one of claims 1 to 7, further comprising a humidity control module adapted to control the humidity inside the cabinet body.
10. The drying cabinet for concentrated protein according to any one of claims 1 to 7, further comprising a control module including a control screen disposed on the cabinet body.
CN202322712176.7U 2023-10-10 2023-10-10 Drying oven suitable for concentrated protein Active CN219976936U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202322712176.7U CN219976936U (en) 2023-10-10 2023-10-10 Drying oven suitable for concentrated protein

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202322712176.7U CN219976936U (en) 2023-10-10 2023-10-10 Drying oven suitable for concentrated protein

Publications (1)

Publication Number Publication Date
CN219976936U true CN219976936U (en) 2023-11-07

Family

ID=88588422

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202322712176.7U Active CN219976936U (en) 2023-10-10 2023-10-10 Drying oven suitable for concentrated protein

Country Status (1)

Country Link
CN (1) CN219976936U (en)

Similar Documents

Publication Publication Date Title
CN107560024B (en) High-precision high-uniformity clean room system
CN208025742U (en) A kind of ventilating system for scientific experiment
CN102589948A (en) Biological sample processing box
CN104791926B (en) A kind of air-treatment unit and its control method
CN219976936U (en) Drying oven suitable for concentrated protein
CN207797590U (en) A kind of red yeast rice drying unit
CN207081089U (en) Air conditioner
CN109701670A (en) Program-controlled formula precision growth cabinet
CN2916533Y (en) Low temperature drier by using slope type circulation drying
CN114204430A (en) Dehumidification device of outdoor electric power cabinet
CN209894566U (en) Test paper strip constant temperature incubation box
CN115043066A (en) Clinical laboratory uses reagent storage device
CN209726414U (en) Family formula constant temperature and humidity perseverance oxygen type Fresh air handling units
CN217777849U (en) Nylon humidifying and toughening treatment equipment
CN217085597U (en) Temperature control device for constant-temperature type nutriment experiments
CN209289588U (en) A kind of VOC, formaldehyde accelerate vaporization chamber
CN208261504U (en) A kind of cabinet type printer gas cleaning plant
CN112628903A (en) Dehumidification new trend plasma sterilization system of supplementary refrigeration heat production in area
CN214179750U (en) Reagent cabinet
CN216630885U (en) Constant temperature and constant pressure superclean bench
CN215437910U (en) Device for drying and storing high-purity quartz products
CN112444480B (en) Freeze-thaw and dry-wet alternation test device and use method thereof
CN217313515U (en) Laboratory bench cabinet equipped with self-adjusting ventilation system
CN211679238U (en) High-efficient fume chamber for experiments of airing exhaust
CN217278416U (en) Blood separating workstation

Legal Events

Date Code Title Description
GR01 Patent grant
GR01 Patent grant