CN219891483U - Automatic interpretation fluorescence microscope - Google Patents
Automatic interpretation fluorescence microscope Download PDFInfo
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- CN219891483U CN219891483U CN202321583958.9U CN202321583958U CN219891483U CN 219891483 U CN219891483 U CN 219891483U CN 202321583958 U CN202321583958 U CN 202321583958U CN 219891483 U CN219891483 U CN 219891483U
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- 230000001105 regulatory effect Effects 0.000 claims 1
- 238000001514 detection method Methods 0.000 description 9
- 238000010586 diagram Methods 0.000 description 2
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- 230000004075 alteration Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 230000005284 excitation Effects 0.000 description 1
- 238000000799 fluorescence microscopy Methods 0.000 description 1
- 239000007850 fluorescent dye Substances 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
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Abstract
The utility model discloses an automatic interpretation fluorescent microscope, which comprises a support frame, wherein a camera, an ocular lens, an objective lens and a condenser lens are arranged on the support frame; the support frame comprises a base, a C-shaped connecting frame and a strip-shaped supporting block, wherein the strip-shaped supporting block is horizontally arranged above the base, and the C-shaped connecting frame is connected between the base and the strip-shaped supporting block; the ocular is arranged on the strip-shaped supporting block and is connected with the objective lens through the objective lens converter; the condenser is arranged right below the objective lens, an aperture is arranged below the condenser, and the aperture is arranged on the base; an objective table is arranged between the objective lens and the condenser lens; the strip-shaped supporting block is also provided with a fluorescence module for generating fluorescence; the camera is installed on the bar supporting shoe, and the camera is connected with controlling means. According to the utility model, the camera is connected with the control device, and the control device further drives the objective table to perform three-dimensional movement, so that automatic focusing acquisition of images can be realized, the acquisition quality is good, and the degree of automation is high.
Description
Technical Field
The utility model relates to the field of microscopes, in particular to an automatic interpretation fluorescence microscope.
Background
The principle of fluorescence microscopy is a microscopic observation mode in which an optical microscope is combined with a fluorescent dye of a compound by means of an excitation light source. At present, the fluorescence microscope on the market adopts a fluorescence technology detection means, so that the resolution of images is improved, the observation of samples is convenient, and the collection of images of each sample is mostly carried out by manual adjustment. The acquired pictures are free of cells and unclear, so that the problems of missed detection, false detection and the like are caused frequently.
Disclosure of Invention
Based on the technical problems, the utility model provides an automatic interpretation fluorescence microscope.
The technical scheme adopted by the utility model is as follows:
an automatic interpretation fluorescent microscope comprises a support frame, wherein a camera, an ocular, an objective lens and a condenser lens are arranged on the support frame; the support frame comprises a base, a C-shaped connecting frame and a strip-shaped supporting block, wherein the strip-shaped supporting block is horizontally arranged above the base, and the C-shaped connecting frame is connected between the base and the strip-shaped supporting block;
the ocular is arranged on the strip-shaped supporting block and is connected with the objective lens through the objective lens converter; the condenser is arranged right below the objective lens, an aperture is arranged below the condenser, and the aperture is arranged on the base;
an objective table is arranged between the objective lens and the condenser lens;
the strip-shaped supporting block is also provided with a fluorescence module for generating fluorescence;
the camera is installed on the bar supporting shoe, and the camera is connected with controlling means.
Preferably, the objective table is connected with a control module for controlling three-dimensional movement of the objective table;
the control module comprises a first electric push rod, a rod body of the first electric push rod is connected with the objective table, and a cylinder body of the first electric push rod is connected with the bearing block through a vertical support rod;
a Y-axis moving block is arranged above the bearing block, a first sliding groove is formed in the bottom of the Y-axis moving block, a first sliding block matched with the first sliding groove is arranged at the top of the bearing block, the first sliding groove and the first sliding block are both arranged along the Y-axis direction, and a second electric push rod for pushing the Y-axis moving block to move along the Y-axis is also arranged on the bearing block;
a second sliding groove is further formed in the top of the Y-axis moving block, a second sliding block matched with the second sliding groove is arranged below one end of the objective table, and the second sliding groove and the second sliding block are both arranged along the X-axis direction;
the bearing block is also connected with a third electric push rod for controlling the bearing block to vertically lift;
the control device is also respectively connected with the first electric push rod, the second electric push rod and the third electric push rod.
Preferably, a strip-shaped opening is arranged in the middle area of the strip-shaped supporting block, and the ocular lens is embedded in the strip-shaped opening.
Preferably, a fluorescent light source adjusting button and a fluorescent switch for adjusting the fluorescent module are further arranged on the strip-shaped supporting block.
Preferably, a brightness adjusting knob for adjusting the aperture is further arranged on the base.
Preferably, the upper part of the C-shaped connecting frame is fixedly connected with the strip-shaped supporting block, the bottom of the C-shaped connecting frame is hinged with the base, and an adjusting hand wheel for adjusting the rotation angle of the C-shaped connecting frame is further arranged at the hinged position of the C-shaped connecting frame and the base.
The beneficial technical effects of the utility model are as follows:
according to the utility model, the camera is connected with the control device, and the control device further drives the objective table to perform three-dimensional movement, so that automatic focusing acquisition of images can be realized, the image acquisition is simple and quick, the acquisition quality is high, and the degree of automation is high.
Drawings
The utility model is further described with reference to the drawings and detailed description which follow:
FIG. 1 is a schematic diagram of the structural principle of the present utility model;
FIG. 2 is a second angular view of FIG. 1;
FIG. 3 is a third angular view of FIG. 1;
FIG. 4 is a schematic view of the stage arrangement of the present utility model;
fig. 5 is a schematic diagram of the structural principle of the connection between the stage and the control module in the present utility model.
In the figure: the fluorescent lamp comprises a 1-camera, a 2-eyepiece, a 3-objective lens, a 4-condenser, a 5-base, a 6-C-shaped connecting frame, a 7-strip-shaped supporting block, an 8-objective lens converter, a 9-aperture, a 10-objective table, an 11-fluorescent module, a 12-first electric push rod, a 13-vertical support rod, a 14-bearing block, a 15-Y-axis moving block, a 16-first sliding groove, a 17-first sliding block, a 18-second sliding block, a 19-third electric push rod, a 20-fluorescent light source adjusting button, a 21-fluorescent switch, a 22-brightness adjusting knob and a 23-adjusting hand wheel.
Detailed Description
The automatic interpretation fluorescent microscope comprises a support frame, wherein a camera 1, an ocular lens 2, an objective lens 3 and a condenser lens 4 are arranged on the support frame. The support frame includes base 5, C shape link 6 and bar supporting shoe 7, and bar supporting shoe 7 level sets up in the top of base 5, and C shape link 6 connects between base 5 and bar supporting shoe 7. The ocular lens 2 is arranged on a strip-shaped supporting block 7, and the ocular lens 2 is connected with the objective lens 3 through an objective lens converter 8. The condenser lens 4 is disposed right below the objective lens 3, a diaphragm 9 is disposed below the condenser lens 4, and the diaphragm 9 is mounted on the base 5. A stage 10 is provided between the objective lens 3 and the condenser lens 4. A fluorescent module 11 for generating fluorescence is also provided on the bar-shaped support block 7. The camera 1 is installed on the bar-shaped supporting block 7, and the camera 1 is connected with the control device.
The stage 10 is connected to a control module for controlling its three-dimensional movement. The control module comprises a first electric push rod 12, a rod body of the first electric push rod 12 is connected with the objective table 10, and a cylinder body of the first electric push rod is connected with the bearing block 14 through a vertical supporting rod 13. A Y-axis moving block 15 is arranged above the bearing block 14, a first sliding groove 16 is arranged at the bottom of the Y-axis moving block 15, a first sliding block 17 matched with the first sliding groove 16 is arranged at the top of the bearing block 14, and the first sliding groove 16 and the first sliding block 17 are arranged along the Y-axis direction. A second electric push rod for pushing the Y-axis moving block to move along the Y-axis is also provided on the bearing block 14. A second sliding groove is further formed in the top of the Y-axis moving block, a second sliding block 18 matched with the second sliding groove is arranged below one end of the objective table 10, and the second sliding groove and the second sliding block 18 are both arranged along the X-axis direction. The bearing block 14 is also connected with a third electric push rod 19 for controlling the vertical lifting of the bearing block. The control device is also connected to the first electric putter 12, the second electric putter and the third electric putter 19, respectively.
According to the utility model, the camera 1 is connected with the control device, and the control device further drives the objective table to perform three-dimensional movement, so that automatic focusing acquisition of images can be realized, the image acquisition is simple and quick, the acquisition quality is high, and the degree of automation is high. The control device may be a computer or the like.
As a further development of the utility model, a strip-shaped opening is provided in the middle region of the strip-shaped support block 7, into which the eyepiece 2 engages.
Further, a fluorescent light source adjusting button 20 and a fluorescent switch 21 for adjusting the fluorescent module 11 are also provided on the bar-shaped supporting block 7.
Further, a brightness adjusting knob 22 for adjusting the aperture is also provided on the base 5.
Furthermore, the upper part of the C-shaped connecting frame 6 is fixedly connected with the strip-shaped supporting block 7, the bottom of the C-shaped connecting frame 6 is hinged with the base 5, and an adjusting hand wheel 23 for adjusting the rotation angle of the C-shaped connecting frame is further arranged at the hinged position of the C-shaped connecting frame 6 and the base 5.
The automatic interpretation fluorescent microscope solves the problem of missed detection of manual microscopic examination, is connected with a computer and the like through a camera, controls an objective table to perform three-dimensional automatic movement, can automatically focus on the most clear layer for shooting, ensures the definition of each picture, and avoids the problems of missed detection, wrong detection and the like caused by no cells and unclear pictures of the pictures which are always shot before screening in the prior art. And the clear cell real picture can be archived by connecting with a computer, so that the review and the tracing are convenient.
The utility model can automatically collect the graph, analyze and identify the visual field, has simple and quick image collection, high collection quality and high automation degree, and effectively solves the problems of missed detection, false detection and low detection efficiency.
The working process of the utility model is approximately as follows:
the sample smear is dyed and then placed on the object stage, and the control module realizes the three-dimensional movement of the object stage through the first electric push rod 12, the second electric push rod and the third electric push rod 19. Specifically, the objective table drives the sample slide to move to a proper view along the X-axis and Y-axis directions in the horizontal plane, meanwhile, the objective table can be controlled to automatically focus and collect a clear image along the Z-axis (vertical) direction, the microscopic image is dynamically transmitted to the camera to be converted into a digital image, the computer carries out a series of digital processing on the image to obtain Z-axis coordinate information of the sample cell, and the clear image is stored. Then automatically moving to other fields of view to acquire images again and save the images, and finally automatically processing and identifying different formed components.
The parts not described in the above modes can be realized by adopting or referring to the prior art.
Although embodiments of the present utility model have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made therein without departing from the principles and spirit of the utility model, the scope of which is defined in the appended claims and their equivalents.
Claims (6)
1. An automatic interpretation fluorescence microscope, characterized in that: the device comprises a support frame, wherein a camera, an ocular, an objective lens and a condenser lens are arranged on the support frame; the support frame comprises a base, a C-shaped connecting frame and a strip-shaped supporting block, wherein the strip-shaped supporting block is horizontally arranged above the base, and the C-shaped connecting frame is connected between the base and the strip-shaped supporting block;
the ocular is arranged on the strip-shaped supporting block and is connected with the objective lens through the objective lens converter; the condenser is arranged right below the objective lens, an aperture is arranged below the condenser, and the aperture is arranged on the base;
an objective table is arranged between the objective lens and the condenser lens;
the strip-shaped supporting block is also provided with a fluorescence module for generating fluorescence;
the camera is installed on the bar supporting shoe, and the camera is connected with controlling means.
2. An automatic interpretation fluorescence microscope according to claim 1, characterized in that: the objective table is connected with a control module for controlling the three-dimensional movement of the objective table;
the control module comprises a first electric push rod, a rod body of the first electric push rod is connected with the objective table, and a cylinder body of the first electric push rod is connected with the bearing block through a vertical support rod;
a Y-axis moving block is arranged above the bearing block, a first sliding groove is formed in the bottom of the Y-axis moving block, a first sliding block matched with the first sliding groove is arranged at the top of the bearing block, the first sliding groove and the first sliding block are both arranged along the Y-axis direction, and a second electric push rod for pushing the Y-axis moving block to move along the Y-axis is also arranged on the bearing block;
a second sliding groove is further formed in the top of the Y-axis moving block, a second sliding block matched with the second sliding groove is arranged below one end of the objective table, and the second sliding groove and the second sliding block are both arranged along the X-axis direction;
the bearing block is also connected with a third electric push rod for controlling the bearing block to vertically lift;
the control device is also respectively connected with the first electric push rod, the second electric push rod and the third electric push rod.
3. An automatic interpretation fluorescence microscope according to claim 1, characterized in that: a strip-shaped opening is arranged in the middle area of the strip-shaped supporting block, and the ocular lens is embedded into the strip-shaped opening.
4. An automatic interpretation fluorescence microscope according to claim 1, characterized in that: and a fluorescent light source adjusting button and a fluorescent switch for adjusting the fluorescent module are also arranged on the strip-shaped supporting block.
5. An automatic interpretation fluorescence microscope according to claim 1, characterized in that: the base is also provided with a brightness adjusting knob for adjusting the aperture.
6. An automatic interpretation fluorescence microscope according to claim 1, characterized in that: the upper portion and the bar supporting shoe fixed connection of C shape link, the bottom and the base of C shape link are articulated, still are provided with the regulating hand wheel that is used for adjusting C shape link rotation angle in C shape link and the articulated department of base.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202321583958.9U CN219891483U (en) | 2023-06-20 | 2023-06-20 | Automatic interpretation fluorescence microscope |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202321583958.9U CN219891483U (en) | 2023-06-20 | 2023-06-20 | Automatic interpretation fluorescence microscope |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN219891483U true CN219891483U (en) | 2023-10-24 |
Family
ID=88400486
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202321583958.9U Active CN219891483U (en) | 2023-06-20 | 2023-06-20 | Automatic interpretation fluorescence microscope |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN219891483U (en) |
-
2023
- 2023-06-20 CN CN202321583958.9U patent/CN219891483U/en active Active
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Inventor after: Liang Jie Inventor after: Zhang Bei Inventor after: Jiang Suli Inventor after: Li Wei Inventor after: Song Meiying Inventor after: Meng Haining Inventor before: Jiang Suli Inventor before: Liang Jie Inventor before: Zhang Bei Inventor before: Li Wei Inventor before: Song Meiying Inventor before: Meng Haining |