CN219848986U - Ultrafiltration concentration and replacement device for liquid enzyme preparation - Google Patents
Ultrafiltration concentration and replacement device for liquid enzyme preparation Download PDFInfo
- Publication number
- CN219848986U CN219848986U CN202320995076.7U CN202320995076U CN219848986U CN 219848986 U CN219848986 U CN 219848986U CN 202320995076 U CN202320995076 U CN 202320995076U CN 219848986 U CN219848986 U CN 219848986U
- Authority
- CN
- China
- Prior art keywords
- ultrafiltration
- liquid
- tank
- circulation
- enzyme
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 238000000108 ultra-filtration Methods 0.000 title claims abstract description 141
- 239000007788 liquid Substances 0.000 title claims abstract description 121
- 102000004190 Enzymes Human genes 0.000 title claims abstract description 74
- 108090000790 Enzymes Proteins 0.000 title claims abstract description 74
- 238000002360 preparation method Methods 0.000 title claims abstract description 56
- 239000012528 membrane Substances 0.000 claims abstract description 61
- 238000006073 displacement reaction Methods 0.000 claims abstract description 27
- 230000001105 regulatory effect Effects 0.000 claims abstract description 12
- 238000005070 sampling Methods 0.000 claims description 13
- 238000001514 detection method Methods 0.000 claims description 12
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 11
- 238000003756 stirring Methods 0.000 claims description 6
- 239000000243 solution Substances 0.000 abstract description 21
- 238000004519 manufacturing process Methods 0.000 abstract description 8
- 239000007853 buffer solution Substances 0.000 abstract description 5
- 238000012797 qualification Methods 0.000 abstract description 2
- 229940088598 enzyme Drugs 0.000 description 55
- 230000000694 effects Effects 0.000 description 11
- 238000000034 method Methods 0.000 description 11
- 230000000712 assembly Effects 0.000 description 8
- 238000000429 assembly Methods 0.000 description 8
- 102000004169 proteins and genes Human genes 0.000 description 5
- 108090000623 proteins and genes Proteins 0.000 description 5
- 241000894006 Bacteria Species 0.000 description 4
- 239000012141 concentrate Substances 0.000 description 4
- 238000005516 engineering process Methods 0.000 description 4
- 238000000605 extraction Methods 0.000 description 4
- 239000000126 substance Substances 0.000 description 4
- 238000007599 discharging Methods 0.000 description 3
- 150000003839 salts Chemical class 0.000 description 3
- 238000000926 separation method Methods 0.000 description 3
- 239000000463 material Substances 0.000 description 2
- 238000011084 recovery Methods 0.000 description 2
- 239000002253 acid Substances 0.000 description 1
- 239000003929 acidic solution Substances 0.000 description 1
- 230000002378 acidificating effect Effects 0.000 description 1
- 239000003513 alkali Substances 0.000 description 1
- 239000012670 alkaline solution Substances 0.000 description 1
- 239000000872 buffer Substances 0.000 description 1
- 150000001720 carbohydrates Chemical class 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 238000011109 contamination Methods 0.000 description 1
- 230000001276 controlling effect Effects 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 230000018044 dehydration Effects 0.000 description 1
- 238000006297 dehydration reaction Methods 0.000 description 1
- 229940079919 digestives enzyme preparation Drugs 0.000 description 1
- 239000003792 electrolyte Substances 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 239000012535 impurity Substances 0.000 description 1
- 230000002779 inactivation Effects 0.000 description 1
- 229910017053 inorganic salt Inorganic materials 0.000 description 1
- 150000002500 ions Chemical class 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 238000004321 preservation Methods 0.000 description 1
Abstract
The ultrafiltration concentration and displacement device for the liquid enzyme preparation comprises a displacement liquid preparation tank, an ultrafiltration circulation tank and an ultrafiltration membrane component, wherein the top of the ultrafiltration circulation tank is communicated with the bottom of the displacement liquid preparation tank, the bottom of the ultrafiltration circulation tank is communicated with an enzyme liquid feed inlet of the ultrafiltration membrane component through an ultrafiltration circulation pipeline, a tank bottom discharge valve, an ultrafiltration circulation pump, a filter and a membrane front regulating valve are sequentially arranged on the ultrafiltration circulation pipeline, and an enzyme liquid discharge pipeline with an enzyme liquid discharge valve is also communicated on the ultrafiltration circulation pipeline between the filter and the membrane front regulating valve; the concentrated solution outlet of the ultrafiltration membrane component is communicated with the top of the ultrafiltration circulating tank through a concentrated solution return pipeline, and the clear solution outlet of the ultrafiltration membrane component is communicated with the top of the ultrafiltration circulating tank through a clear solution return pipeline. The buffer solution preparation tank and the ultrafiltration membrane equipment are scientifically and effectively combined to form the production system with stable and high operation, so that the qualification rate of finished products can be improved, and the liquid enzyme preparation with stable quality is obtained.
Description
Technical Field
The utility model relates to the technical field of extraction and production of enzyme preparations, in particular to an ultrafiltration concentration and replacement device for a liquid enzyme preparation.
Background
The ultrafiltration concentration is a separation method for obtaining a target product by removing water molecules passing through a membrane system by using an ultrafiltration membrane system in a mixed feed liquid of water and solute in a pressurizing mode and intercepting the target solute.
The enzyme preparation extracted from microorganisms often contains excessive water, inorganic salt, saccharides and other low molecular substances, and the excessive substances have great influence on the color, smell, preservation, transportation and production application of the enzymes, and the excessive components are generally removed by concentration, replacement and other methods, but the existing technical methods can remove the components, but the process is complicated, and the concentration and replacement processes need to be operated repeatedly. In the production of liquid enzyme preparation, the membrane separation technology is usually used for dehydration concentration, the membrane separation technology is used for concentration and replacement of enzyme, the operation process is simple, the molecular mass of the enzyme preparation is generally 10000-100000Da, the application range of ultrafiltration membrane equipment and ultrafiltration technology is also met, the ultrafiltration concentration technology is used for concentrating enzyme liquid, low molecular and salt substances dissolved in water can be removed together with the water through membrane holes, and the enzyme is concentrated and reserved. The more ions, salt components and impurity substances contained in the enzyme preparation, the higher the electric conductivity of the enzyme preparation, and the effect after ultrafiltration concentration replacement can be judged by utilizing the change condition of the electric conductivity. The temperature is also a key factor influencing the activity and conductivity change of the enzyme, the temperature of the stable concentrated solution is controlled to be 4-10 ℃, and the enzyme protein is denatured due to the too high or the too low temperature, so that the activity of the enzyme preparation is reduced. In addition, the control of proper extraction temperature can reduce the probability of mixed bacteria pollution and enzyme inactivation, so that the extraction yield and application effect of the enzyme are improved.
In the existing ultrafiltration process for extracting the liquid enzyme preparation, in order to improve the enzyme activity of the liquid enzyme preparation, the quality and the yield of the finished product generally need repeated replacement of the buffer solution. The buffer is a solution capable of maintaining the pH value independent of pH value, so that various cells can only move within a small pH range, and a stable buffer system is needed to maintain the whole process undisturbed. The buffer solution contains acid, salt or alkali, etc., so that the influence caused by the addition of the acidic or alkaline solution to the outside can be counteracted to a certain extent. In the application process, the enzyme activity is reduced or even inactivated due to the large change of the PH, so that the enzyme preparation cannot be effectively applied in the subsequent production work, and the main purpose of adding the buffer solution for replacement in the extraction process is to maintain the stability of the PH and reach the specified quality index. In the repeated replacement and ultrafiltration concentration process, as the concentration of the concentrated solution can be gradually increased every time of replacement, the pressure difference between the front membrane and the rear membrane of the ultrafiltration membrane is gradually increased, the pressure of the ultrafiltration system is increased, the ultrafiltration membrane is damaged for a long time, the filtration effect is affected, and the yield of the concentrated solution is reduced.
Disclosure of Invention
Aiming at the defects of the prior art, the utility model provides the ultrafiltration concentration and replacement device for the liquid enzyme preparation, which can conveniently and effectively complete the production task requirements, reduce the bacteria contamination risk caused by manual operation and improve the product qualification rate.
The technical problems to be solved by the utility model are realized by the following technical proposal. The utility model relates to a liquid enzyme preparation ultrafiltration concentration and displacement device, which comprises a displacement liquid preparation tank, an ultrafiltration circulation tank and an ultrafiltration membrane component, wherein the top of the ultrafiltration circulation tank is communicated with the bottom of the displacement liquid preparation tank, the bottom of the ultrafiltration circulation tank is provided with a displacement liquid inlet valve, the bottom of the ultrafiltration circulation tank is communicated with an enzyme liquid feed inlet of the ultrafiltration membrane component through an ultrafiltration circulation pipeline, a tank bottom discharge valve, an ultrafiltration circulation pump, a filter and a membrane front regulating valve are sequentially arranged on the ultrafiltration circulation pipeline, and an enzyme liquid discharge pipeline with an enzyme liquid discharge valve is also communicated on the ultrafiltration circulation pipeline between the filter and the membrane front regulating valve;
the concentrated solution outlet of the ultrafiltration membrane component is communicated with the top of the ultrafiltration circulating tank through a concentrated solution return pipeline, the clear solution outlet of the ultrafiltration membrane component is communicated with the top of the ultrafiltration circulating tank through a clear solution return pipeline, a concentrated solution return tank valve is arranged on the concentrated solution return pipeline, and a clear solution return tank valve and a clear solution emptying valve are arranged on the clear solution return pipeline.
The technical problem to be solved by the utility model can be further solved by the following technical scheme, and for the ultrafiltration concentration and replacement device of the liquid enzyme preparation, 2 ultrafiltration circulating tanks are arranged in parallel.
The technical problem to be solved by the utility model can be further solved by the following technical scheme, and each ultrafiltration circulation tank is provided with a replacement liquid preparation tank for the ultrafiltration concentration and replacement device of the liquid enzyme preparation.
The technical problem to be solved by the utility model can be further solved by the following technical scheme, and for the ultrafiltration concentration and replacement device for the liquid enzyme preparation, 2 ultrafiltration membrane components are arranged, and 2 ultrafiltration membrane components are arranged in series.
The technical problem to be solved by the utility model can be further solved by the following technical scheme, and the ultrafiltration concentration and replacement device for the liquid enzyme preparation is further provided with a clear liquid sampling valve, a concentrated liquid sampling valve and an emptying valve on an ultrafiltration membrane component.
The technical problem to be solved by the utility model can be further solved by the following technical scheme, for the liquid enzyme preparation ultrafiltration concentration and replacement device, the ultrafiltration circulation tank comprises a tank body, the top of the tank body is provided with a stirring device, the outer side of the tank body is sleeved with a jacket device which is convenient for entering and exiting chilled water, and the tank body is also provided with a PH detection device, a temperature detection device and a liquid level detection device.
The technical problem to be solved by the utility model can be further solved by the following technical scheme, for the liquid enzyme preparation ultrafiltration concentration and replacement device, the replacement liquid preparation tank comprises a tank body, the top of the tank body is provided with a stirring device, and the outer side of the tank body is sleeved with a jacket device which is convenient for entering and exiting chilled water.
The technical problem to be solved by the utility model can be further solved by the following technical scheme, for the liquid enzyme preparation ultrafiltration concentration and displacement device, the enzyme liquid feed inlet of the ultrafiltration membrane component is provided with a variable-frequency ultrafiltration feed pump, and the concentrated liquid outlet of the ultrafiltration membrane component is also provided with a conductivity meter.
Compared with the prior art, the ultrafiltration concentration and replacement device for the liquid enzyme preparation provided by the utility model has the advantages of scientific and reasonable arrangement, simple operation, small occupied area, low field requirement, reliable operation, effective simplification of the ultrafiltration concentration and replacement process, shortened production time, reduced risk of bringing mixed bacteria into the concentrated solution after long-time circulating operation, stability and improvement of product quality, and greatly reduced protein and enzyme activity loss of the liquid enzyme preparation after ultrafiltration concentration and replacement, and protein and enzyme activity recovery rate reaching more than 95% and 97%.
Drawings
Fig. 1 is a schematic structural view of the present utility model.
Detailed Description
For the purpose of making the objects, technical solutions and advantages of the embodiments of the present utility model more apparent, the technical solutions in the embodiments of the present utility model will be clearly and completely described below with reference to the accompanying drawings, and it is apparent that the described embodiments are some embodiments of the present utility model, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the utility model without making any inventive effort, are intended to be within the scope of the utility model.
Referring to fig. 1, a liquid enzyme preparation ultrafiltration concentration and displacement device comprises displacement liquid preparation tanks 1 and 3, ultrafiltration circulation tanks 9 and 11 and ultrafiltration membrane assemblies 24 and 25, wherein the displacement liquid preparation tanks 1 and 3 are used for containing the prepared displacement liquid, the tops of the ultrafiltration circulation tanks 9 and 11 are communicated with the bottoms of the displacement liquid preparation tanks 1 and 3 so as to facilitate the delivery of the displacement liquid into the ultrafiltration circulation tanks 9 and 11, displacement liquid inlet tank valves 2 and 4 are arranged at the bottoms of the displacement liquid preparation tanks 1 and 3 and are used for controlling the delivery of the displacement liquid, the bottoms of the ultrafiltration circulation tanks 9 and 11 are communicated with enzyme liquid feed ports of the ultrafiltration membrane assemblies 24 and 25 through ultrafiltration circulation pipelines so as to facilitate the delivery of enzyme liquid in the ultrafiltration circulation tanks 9 and 11 into the ultrafiltration membrane assemblies 24 and 25, tank bottom discharge valves 10 and 12, an ultrafiltration circulation pump 13, a filter 14 and a membrane front regulating valve 16 are sequentially arranged on the ultrafiltration circulation pipelines, a pressure detection device and a liquid check device can be further arranged, an enzyme liquid discharge pipeline with an enzyme liquid discharge valve 15 is communicated on the ultrafiltration circulation pipeline between the filter 14 and the membrane front regulating valve 16 so as to facilitate the external enzyme liquid output unit 22;
in order to realize concentration and displacement treatment of enzyme liquid, the concentrate outlets of the ultrafiltration membrane assemblies 24 and 25 are communicated with the tops of the ultrafiltration circulating tanks 9 and 11 through concentrate return pipelines, the clear liquid outlets of the ultrafiltration membrane assemblies 24 and 25 are communicated with the tops of the ultrafiltration circulating tanks 9 and 11 through clear liquid return pipelines, concentrate return tank valves 6 and 7 are arranged on the concentrate return pipelines, and clear liquid return tank valves 5 and 8 and clear liquid emptying valves 26 are arranged on the clear liquid return pipelines.
Preferably, 2 ultrafiltration circulation tanks 9, 11 are arranged in parallel, and each ultrafiltration circulation tank 9, 11 is provided with a replacement liquid preparation tank 1, 3; the ultrafiltration membrane components 24 and 25 are arranged in 2, and the 2 ultrafiltration membrane components 24 and 25 are arranged in series.
The ultrafiltration membrane components 24 and 25 are also provided with clear liquid sampling valves 20 and 21, concentrated liquid sampling valves 17 and 18 and an evacuation valve 19, and the arrangement of the clear liquid sampling valves 20 and 21 and the concentrated liquid sampling valves 17 and 18 is convenient for sampling and detecting clear liquid and concentrated liquid separated by the ultrafiltration membrane components 24 and 25 so as to be matched with discharging operation; the evacuation valve 19 is not required during operation and is only opened to allow air to enter when it is used to collect the last material remaining in the ultrafiltration membrane modules 24, 25.
Specifically, the ultrafiltration circulation tanks 9 and 11 comprise tank bodies, wherein a stirring device is arranged at the top of each tank body, jacket devices convenient for entering and exiting chilled water are sleeved on the outer sides of the tank bodies, and a PH detection device, a temperature detection device and a liquid level detection device are also arranged on the tank bodies;
the replacement liquid preparation tanks 1 and 3 comprise tank bodies, wherein a stirring device is arranged at the top of each tank body, and jacket devices which are convenient for entering and exiting chilled water are sleeved on the outer sides of the tank bodies;
in order to further cooperate with the normal operation of the ultrafiltration membrane assemblies 24 and 25, the enzyme liquid feed inlets of the ultrafiltration membrane assemblies 24 and 25 are provided with variable-frequency ultrafiltration feed pumps, and the concentrated liquid outlets of the ultrafiltration membrane assemblies 24 and 25 are also provided with a conductivity meter 23.
The working flow of the utility model is as follows:
when the feed liquid in the ultrafiltration circulation tank 9 or 11 reaches 60%, starting an ultrafiltration circulation program, sequentially starting a tank bottom discharge valve 10 or 12, collecting feed liquid in a pipeline before the ultrafiltration circulation pump 13, starting a membrane front regulating valve 16, an ultrafiltration concentrated liquid recharging valve 6 or 7, an ultrafiltration clear liquid recharging valve 5 or 8, starting the ultrafiltration circulation pump 13, enabling enzyme liquid to enter the membrane front regulating valve 16 through a filter 14, setting the pressure before the membrane to be 0.12Mpa, automatically increasing or decreasing the ultrafiltration pump frequency conversion and the membrane front regulating valve 16 to enable the pressure to reach a set value, starting circulation of feed liquid in the ultrafiltration circulation tank 9 or 11, continuously separating clear liquid and concentrated liquid in ultrafiltration membrane groups 24 and 25, starting discharging when clear liquid sampling valves 20 and 21 and concentrated liquid sampling valves 17 and 18 are detected to be qualified, closing the clear liquid recharging valve 5 or 8, opening a clear liquid blow-down valve 26, and continuously concentrating the liquid enzyme volume;
when the enzyme liquid volume is concentrated to 20%, the clear liquid return tank valve 5 or 8 is opened, the clear liquid drain valve 26 is closed, the ultrafiltration circulating pump 13 is closed, replacement is started immediately, the replacement liquid preparation tank 1 or 3 is the replacement liquid with the complete preparation, the replacement liquid inlet tank valve 2 or 4 is opened, when the inner volume of the ultrafiltration circulating tank 9 or 11 reaches 40%, the replacement liquid inlet tank valve 2 or 4 is closed, the ultrafiltration circulating pump 13 is opened, the ultrafiltration membrane is used for circulating inlet and outlet materials, after timing for 30min is completed, the clear liquid drain valve 26 is opened, the clear liquid return tank valve 5 or 8 is closed, replacement concentration is started, and when the concentration volume reaches 20%, the second replacement concentration operation is started, and the circulation is repeated in this way; when the conductivity of the electrolyte is measured by the conductivity meter 23 to meet the replacement requirement, the concentrated liquid sampling valves 17 and 18 start sampling and detection, the replacement is stopped after the detection is qualified, the enzyme liquid discharging valve 15 is opened after the concentration of the enzyme liquid is concentrated to the protein concentration required by the process, the pre-membrane regulating valve 16 is closed, and the enzyme liquid is pumped into the next unit 22.
The ultrafiltration concentration replacement device for the liquid enzyme preparation provided by the utility model has the advantages of scientific and reasonable arrangement, simple operation, small occupied area, low requirements on the field and reliable operation, effectively simplifies the ultrafiltration concentration replacement process, shortens the production time, reduces the risk of introducing mixed bacteria when the concentrated solution is operated for a long time, stabilizes and improves the product quality, and greatly reduces the loss of protein and enzyme activity of the liquid enzyme preparation after ultrafiltration concentration replacement, wherein the recovery rate of the protein and enzyme activity is more than 95% and 97%.
Claims (8)
1. The utility model provides a liquid enzyme preparation ultrafiltration concentration and displacement device which characterized in that: the ultrafiltration device comprises a replacement liquid preparation tank, an ultrafiltration circulation tank and an ultrafiltration membrane component, wherein the top of the ultrafiltration circulation tank is communicated with the bottom of the replacement liquid preparation tank, a replacement liquid inlet valve is arranged at the bottom of the replacement liquid preparation tank, the bottom of the ultrafiltration circulation tank is communicated with an enzyme liquid feed inlet of the ultrafiltration membrane component through an ultrafiltration circulation pipeline, a tank bottom discharge valve, an ultrafiltration circulation pump, a filter and a membrane front regulating valve are sequentially arranged on the ultrafiltration circulation pipeline, and an enzyme liquid discharge pipeline with an enzyme liquid discharge valve is also communicated on the ultrafiltration circulation pipeline between the filter and the membrane front regulating valve;
the concentrated solution outlet of the ultrafiltration membrane component is communicated with the top of the ultrafiltration circulating tank through a concentrated solution return pipeline, the clear solution outlet of the ultrafiltration membrane component is communicated with the top of the ultrafiltration circulating tank through a clear solution return pipeline, a concentrated solution return tank valve is arranged on the concentrated solution return pipeline, and a clear solution return tank valve and a clear solution emptying valve are arranged on the clear solution return pipeline.
2. The liquid enzyme preparation ultrafiltration concentration and displacement device according to claim 1, wherein: the ultrafiltration circulation tanks are arranged in parallel, and 2 ultrafiltration circulation tanks are arranged in parallel.
3. The liquid enzyme preparation ultrafiltration concentration and displacement device according to claim 1 or 2, wherein: each ultrafiltration circulation tank is provided with a displacement liquid preparation tank.
4. The liquid enzyme preparation ultrafiltration concentration and displacement device according to claim 1, wherein: the ultrafiltration membrane components are arranged in series, and 2 ultrafiltration membrane components are arranged in series.
5. The ultrafiltration concentration and displacement device for liquid enzyme preparation according to claim 1 or 4, wherein: the ultrafiltration membrane component is also provided with a clear liquid sampling valve, a concentrated liquid sampling valve and an exhaust valve.
6. The liquid enzyme preparation ultrafiltration concentration and displacement device according to claim 1, wherein: the ultrafiltration circulation tank comprises a tank body, wherein the top of the tank body is provided with a stirring device, the outer side of the tank body is sleeved with a jacket device which is convenient for entering and exiting chilled water, and the tank body is also provided with a PH detection device, a temperature detection device and a liquid level detection device.
7. The liquid enzyme preparation ultrafiltration concentration and displacement device according to claim 1, wherein: the replacement liquid preparation tank comprises a tank body, wherein the top of the tank body is provided with a stirring device, and the outer side of the tank body is sleeved with a jacket device which is convenient for entering and exiting chilled water.
8. The liquid enzyme preparation ultrafiltration concentration and displacement device according to claim 1, wherein: the enzyme liquid feed inlet of the ultrafiltration membrane component is provided with a variable frequency ultrafiltration feed pump, and the concentrated liquid outlet of the ultrafiltration membrane component is also provided with a conductivity tester.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202320995076.7U CN219848986U (en) | 2023-04-27 | 2023-04-27 | Ultrafiltration concentration and replacement device for liquid enzyme preparation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202320995076.7U CN219848986U (en) | 2023-04-27 | 2023-04-27 | Ultrafiltration concentration and replacement device for liquid enzyme preparation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN219848986U true CN219848986U (en) | 2023-10-20 |
Family
ID=88370595
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202320995076.7U Active CN219848986U (en) | 2023-04-27 | 2023-04-27 | Ultrafiltration concentration and replacement device for liquid enzyme preparation |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN219848986U (en) |
-
2023
- 2023-04-27 CN CN202320995076.7U patent/CN219848986U/en active Active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US2371208A (en) | System of continuous fermentation | |
| CN112262209A (en) | Cell culture system and cell culture method | |
| US10752875B2 (en) | System and method for extracting ethanol from a fermentation broth | |
| CN102586088B (en) | Sterile ultrafiltration concentration enzymic preparation fermentation liquid post-extraction production line | |
| CN219848986U (en) | Ultrafiltration concentration and replacement device for liquid enzyme preparation | |
| CN106518700A (en) | Glutamicacid membrane method production process | |
| CN218579951U (en) | Biological product concentration system | |
| CN102399687A (en) | Multifunctional post-extraction production line for enzyme preparation fermentation liquid | |
| CN202201898U (en) | Sterility ultrafiltration concentrated type post extraction product line for fermentation liquor of enzymic preparations | |
| CN212504802U (en) | A equipment for concentrating mesenchymal stem cell exosome | |
| CN213506262U (en) | Ultrafiltration raffinate recycle system | |
| CN210905686U (en) | Device for improving membrane concentration multiple and concentrated solution concentration | |
| CN208762434U (en) | A kind of reaction unit of the process for refining for neomycinsulphate | |
| CN210097403U (en) | Whey liquid nanofiltration membrane separation and concentration system | |
| CN108970174B (en) | Extraction system and method for metabolites in microalgae cells | |
| CN215428241U (en) | Ultrafiltration small test device | |
| CN206033773U (en) | Prokaryotes protein pretreatment systems | |
| CN203295493U (en) | Liquid enzyme preparation ultrafiltration concentration system | |
| CN210287190U (en) | Active collagen peptide liquid concentration and separation device | |
| CN114983893B (en) | Preparation method and preparation device of anti-sugar composition | |
| CN214345637U (en) | A hierarchical extraction element that is arranged in external cell culture liquid skin cell growth factor | |
| CN105420302B (en) | A kind of serialization microbial method prepares the method and device of acrylamide | |
| CN216497963U (en) | Pilot plant for filtering concentrated solution ceramic membrane of papermaking-method reconstituted tobacco | |
| CN102399686A (en) | After-extraction production line for fermentation liquid of enzymic preparation | |
| JPH10211423A (en) | Method for separation and recovery of objective component |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant |