CN106518700A - Glutamicacid membrane method production process - Google Patents
Glutamicacid membrane method production process Download PDFInfo
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- CN106518700A CN106518700A CN201610845477.9A CN201610845477A CN106518700A CN 106518700 A CN106518700 A CN 106518700A CN 201610845477 A CN201610845477 A CN 201610845477A CN 106518700 A CN106518700 A CN 106518700A
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- concentration
- milipore filter
- liquid
- glutamic acid
- impurities
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/38—Separation; Purification; Stabilisation; Use of additives
- C07C227/40—Separation; Purification
Abstract
The invention discloses an extraction process of the glutamicacid membrane method production. The process comprises the steps of step 1, fermenting solution, 2, passing through a disinfection and ultra-filtering membrane, step 3, passing through a impurity-removing ultra-filtering membrane, step 4, pretreating with concentration membrane, step 5, conducting heat concentration, and step 6, acquiring crude product. The production process applies membrane method to reduce waste water discharge amount, thus not only saving cost, but also enhancing the production efficiency. Moreover the process excludes the flocculation sedimentation and plate filtration, thus reducing the consumption of flocculant, and improving the operation environment.
Description
Technical field
The present invention relates to extraction technology of glutamic acid, and in particular to a kind of extraction process of glutamic acid embrane method production.
Background technology
Glutamic acid, is a kind of acidic amino acid.Intramolecular contains two carboxyls, and chemical name is alpha-amido glutaric acid.Its list
Sodium salt, trade name are monosodium glutamate, are important flavouring.Account for importantly during glutamic acid protein metabolism in vivo
Position, participates in many important chemical reaction in animal, plant and microorganism.
When traditional fermentation method produces glutamic acid, in its zymotic fluid, contain substantial amounts of thalline, albumen, pigment and various salt
Point, ion etc., seriously constrain the quality of production glutamic acid finished product.Traditional plate-frame filtering, in the clear liquid after filtration, impurity is high,
And high cost, yield are low.Traditional decolouring and secondary from skill of handing over, high cost, labor strength be big and wastewater discharge
Greatly, environmental pollution is more serious, is unfavorable for social enviroment protection benefit.
The content of the invention
The invention provides a kind of extraction process of glutamic acid embrane method production, system energy in effectively solving traditional processing technology
The problems such as consumption is high, yield rate is low, wastewater discharge is big, pollution is heavy.
A kind of extraction process of glutamic acid embrane method production of the present invention, comprises the following steps：
Step one, appropriate zymotic fluid is put in milipore filter；
Zymotic fluid in milipore filter is carried out heat sterilization by step 2, degerming milipore filter, obtains liquid I；
Step 3, removal of impurities milipore filter, will be degerming in step 2 after the liquid I that obtains carry out milipore filter removal of impurities, obtain liquid；
The liquid obtained in step 3 is put into concentration film and is pre-processed, filters particle miscellaneous by step 4, concentration film pretreatment
Matter is simultaneously sterilized, obtains liquid III；
Step 5, heat concentration, by the liquid III obtained in step 4, carries out hot concentration in being put into vessel.
Step 6, crude product, after step 5 heat concentration, cooling acquisition crude product.
Preferably, the step one, zymotic fluid are that fluid nutrient medium connects people microorganism fungus kind, are cultivated through a period of time
Afterwards, microorganism is using the nutrient content in culture medium, synthesis thalline and secretory product, this liquid Jing after microbial metabolism.
Preferably, the step 2, degerming milipore filter, the plate-frame filtering after degerming milipore filter replaces flocculation are filtered
In clear liquid afterwards, impurity content is few, on the one hand improves the adsorbance of resin column；On the other hand the cleaning of resin column can be reduced again
Raw frequency, so as to reduce discharge capacity once from sequence waste water of handing over, reduces the microbiological contamination probability of system, effectively improve product quality and
Yield.
Preferably, the step 3, removal of impurities milipore filter, the glutamic acid separated once after friendship with removal of impurities ultrafiltration membrance filter are sent out
Zymotic fluid, replaces old technique decolouring once after friendship and secondary from skill of handing over, both cost-effective, improves product benefit again, greatly
The discharge capacity for reducing waste water.
It is an advantage of the invention that：
1st, the present invention is using degerming milipore filter is degerming, removal of impurities milipore filter removal of impurities, after aseptic filtration please night impurity content it is few, save
The consumption of flocculant, improves operating environment, reduces the labour intensity of workman, improve production efficiency；Removal of impurities milipore filter removal of impurities, replaces
The decolouring once after friendship of the old technique of tradition and secondary from skill of handing over, not only saves cost, improves operating efficiency, and
The discharge capacity of the waste water for also greatly reducing.Additionally, ultrafiltration can be carried out at normal temperatures, those are to heat-sensitive material, such as medicine egg
It is the separation of white matter preparation etc., concentration, refined, all can carry out in the case where quality is not affected, improve end product quality.
2nd, the pre-concentration before hot concentration is carried out using concentration film in the present invention, most moisture is removed with film concentration,
Because the expense of film concentration is the 1/5-1/10 of hot concentration expense, therefore concentrated using film, concentrated cost greatly reduces, while
Film concentration is real to be carried out at normal temperatures, it is ensured that the quality of product, furthermore the product water of film concentration can also be back to use in production technology,
Production cost is saved.
3rd, the ultrafiltration membrane system rate of recovery is high, and products obtained therefrom is best in quality, is capable of achieving efficiently separating, purifying and high power for material
Number concentration.Processing procedure to constituent in material without any harmful effect, and is separated, purifying, is begun in concentration process without phase transformation
Normal temperature state is in eventually, is particularly well-suited to the process of heat-sensitive substance, it is entirely avoided high temperature destroys this to bioactivator
One drawback, the bioactivator being effectively retained in raw material system and nutrient content；And system energy consumption is low, the production cycle
Short, compared with traditional process equipment, equipment operating cost is low, can effectively reduce production cost, improves Business Economic Benefit.
Description of the drawings
Implementing procedure figure of the accompanying drawing 1 for the present invention.
Specific embodiment
A kind of extraction process of glutamic acid embrane method production of the present invention, comprises the following steps：
Step one, appropriate zymotic fluid is put in milipore filter；
Zymotic fluid in milipore filter is carried out heat sterilization by step 2, degerming milipore filter, obtains liquid I；
Step 3, removal of impurities milipore filter, will be degerming in step 2 after the liquid I that obtains carry out milipore filter removal of impurities, obtain liquid；
The liquid obtained in step 3 is put into concentration film and is pre-processed, filters particle miscellaneous by step 4, concentration film pretreatment
Matter is simultaneously sterilized, obtains liquid III；
Step 5, heat concentration, by the liquid III obtained in step 4, carries out hot concentration in being put into vessel.
Step 6, crude product, after step 5 heat concentration, cooling acquisition crude product.
The step one, zymotic fluid are that fluid nutrient medium connects people microorganism fungus kind, after a period of time cultivates, microorganism
Using the nutrient content in culture medium, synthesize thalline and secretory product, this liquid Jing after microbial metabolism.The step
Two, degerming milipore filter, the plate-frame filtering after degerming milipore filter replaces flocculation, in the clear liquid after filtration, impurity content is few, and one
Aspect improves the adsorbance of resin column；On the other hand the cleaning and regeneration frequency of resin column can be reduced, so as to reduce once from friendship
The discharge capacity of operation waste water, reduces the microbiological contamination probability of system, effectively improves product quality and yield.The step 3, removal of impurities surpass
Filter membrane, with removal of impurities ultrafiltration membrance filter separation glutami acid fermentation liquor once after friendship, replaces the decolouring once after friendship of old technique
It is with secondary from skill of handing over, both cost-effective, product benefit is improved again, greatly reduces the discharge capacity of waste water.
It is obvious to a person skilled in the art that the invention is not restricted to the details of above-mentioned one exemplary embodiment, Er Qie
In the case of spirit or essential attributes without departing substantially from the present invention, the present invention can be realized in other specific forms.Therefore, no matter
From the point of view of which point, example all should be regarded as exemplary, and be nonrestrictive, the scope of the present invention is by appended power
Profit is required rather than described above is limited, it is intended that all in the implication and scope of the equivalency of claim by falling
Change is included in the present invention.Any reference in claim should not be considered as and limit involved claim.
Claims (5)
1. the extraction process that a kind of glutamic acid embrane method is produced, it is characterised in that comprise the following steps：
Step one, appropriate zymotic fluid is put in milipore filter；
Zymotic fluid in milipore filter is carried out heat sterilization by step 2, degerming milipore filter, obtains liquid I；
Step 3, removal of impurities milipore filter, will be degerming in step 2 after the liquid I that obtains carry out milipore filter removal of impurities, obtain liquid；
The liquid obtained in step 3 is put into concentration film and is pre-processed, filters particle miscellaneous by step 4, concentration film pretreatment
Matter is simultaneously sterilized, obtains liquid III；
Step 5, heat concentration, by the liquid III obtained in step 4, carries out hot concentration in being put into vessel；
Step 6, crude product, after step 5 heat concentration, cooling acquisition crude product.
2. the extraction process that a kind of glutamic acid embrane method according to claims 1 is produced, it is characterised in that the step
One, zymotic fluid is that fluid nutrient medium connects people microorganism fungus kind, and after a period of time cultivates, microorganism is using the battalion in culture medium
Form point, synthesis thalline and secretory product, this liquid Jing after microbial metabolism.
3. the extraction process that a kind of glutamic acid embrane method according to claims 1 is produced, it is characterised in that the step
Two, degerming milipore filter, the plate-frame filtering after degerming milipore filter replaces flocculation, in the clear liquid after filtration, impurity content is few, and one
Aspect improves the adsorbance of resin column；On the other hand the cleaning and regeneration frequency of resin column can be reduced, so as to reduce once from friendship
The discharge capacity of operation waste water, reduces the microbiological contamination probability of system, effectively improves product quality and yield.
4. the extraction process that a kind of glutamic acid embrane method according to claims 1 is produced, it is characterised in that the step
Three, removal of impurities milipore filter, with removal of impurities ultrafiltration membrance filter separation glutami acid fermentation liquor once after friendship, replaces old technique once from friendship
Rear decolouring and secondary from skill of handing over, it is both cost-effective, product benefit is improved again, greatly reduces the discharge capacity of waste water.
5. the extraction process that a kind of glutamic acid embrane method according to claims 1 is produced, it is characterised in that the step
Four, concentration film pretreatment is put into glutami acid fermentation liquor in concentration membranous system, and running temperature is less than 50 DEG C, at filter
After reason, most of moisture in glutami acid fermentation liquor is removed, through circulating pump circulating filtration, by thalline, mycelium, insolubility egg
The Impurity removals such as white and soluble large molecule albumen.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
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| CN201610845477.9A CN106518700A (en) | 2016-09-24 | 2016-09-24 | Glutamicacid membrane method production process |
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| CN201610845477.9A CN106518700A (en) | 2016-09-24 | 2016-09-24 | Glutamicacid membrane method production process |
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| CN201610845477.9A Pending CN106518700A (en) | 2016-09-24 | 2016-09-24 | Glutamicacid membrane method production process |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107286034A (en) * | 2017-08-20 | 2017-10-24 | 合肥信达膜科技有限公司 | A kind of glutamic acid preparation method |
| CN108606299A (en) * | 2018-05-08 | 2018-10-02 | 刘柏海 | A method of producing monosodium glutamate using multistage sterilization technique |
| CN113755540A (en) * | 2021-08-06 | 2021-12-07 | 合肥信达膜科技有限公司 | Alanine production method based on membrane separation process |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104262014A (en) * | 2014-10-07 | 2015-01-07 | 内蒙古阜丰生物科技有限公司 | Biological bacterial fertilizer prepared from glutamic acid fermentation wastes |
-
2016
- 2016-09-24 CN CN201610845477.9A patent/CN106518700A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104262014A (en) * | 2014-10-07 | 2015-01-07 | 内蒙古阜丰生物科技有限公司 | Biological bacterial fertilizer prepared from glutamic acid fermentation wastes |
Non-Patent Citations (1)
| Title |
|---|
| 刘学文 主编: "《食品科学与工程导论》", 30 April 2007, 化学工业出版社 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107286034A (en) * | 2017-08-20 | 2017-10-24 | 合肥信达膜科技有限公司 | A kind of glutamic acid preparation method |
| CN108606299A (en) * | 2018-05-08 | 2018-10-02 | 刘柏海 | A method of producing monosodium glutamate using multistage sterilization technique |
| CN113755540A (en) * | 2021-08-06 | 2021-12-07 | 合肥信达膜科技有限公司 | Alanine production method based on membrane separation process |
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Application publication date: 20170322 |