CN219831113U - Fluorescent immunoassay is with tongs and integrative device of application of sample needle - Google Patents
Fluorescent immunoassay is with tongs and integrative device of application of sample needle Download PDFInfo
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- CN219831113U CN219831113U CN202320941174.2U CN202320941174U CN219831113U CN 219831113 U CN219831113 U CN 219831113U CN 202320941174 U CN202320941174 U CN 202320941174U CN 219831113 U CN219831113 U CN 219831113U
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- 238000003018 immunoassay Methods 0.000 title claims abstract description 16
- 230000007246 mechanism Effects 0.000 claims abstract description 15
- 238000004458 analytical method Methods 0.000 claims description 13
- 230000005540 biological transmission Effects 0.000 claims description 10
- 238000001514 detection method Methods 0.000 abstract description 9
- 238000002347 injection Methods 0.000 abstract description 8
- 239000007924 injection Substances 0.000 abstract description 8
- 239000000463 material Substances 0.000 abstract description 6
- 230000000694 effects Effects 0.000 abstract description 5
- 238000012423 maintenance Methods 0.000 abstract description 2
- 238000010166 immunofluorescence Methods 0.000 description 10
- 238000000034 method Methods 0.000 description 8
- 238000010185 immunofluorescence analysis Methods 0.000 description 6
- 239000003153 chemical reaction reagent Substances 0.000 description 5
- 238000009826 distribution Methods 0.000 description 4
- 238000004519 manufacturing process Methods 0.000 description 4
- 230000008569 process Effects 0.000 description 4
- 230000009471 action Effects 0.000 description 3
- 230000009286 beneficial effect Effects 0.000 description 2
- 238000007599 discharging Methods 0.000 description 2
- 238000006073 displacement reaction Methods 0.000 description 2
- 230000006872 improvement Effects 0.000 description 2
- 239000000758 substrate Substances 0.000 description 2
- 230000004075 alteration Effects 0.000 description 1
- 238000003759 clinical diagnosis Methods 0.000 description 1
- 230000001276 controlling effect Effects 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000003912 environmental pollution Methods 0.000 description 1
- 239000007850 fluorescent dye Substances 0.000 description 1
- 238000012632 fluorescent imaging Methods 0.000 description 1
- 238000009434 installation Methods 0.000 description 1
- 239000003550 marker Substances 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012544 monitoring process Methods 0.000 description 1
- 239000012474 protein marker Substances 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 238000010186 staining Methods 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 238000003466 welding Methods 0.000 description 1
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Abstract
The utility model relates to a grab hand and sample injection needle integrated device for fluorescence immunoassay, which comprises a base, a vertical plate fixedly arranged at the top of the base, a PLC (programmable logic controller) and an analyzer fixedly arranged on the front surface outside the vertical plate, wherein a placing table is arranged at the top of the base, a tray is detachably arranged at the top of the placing table, a driving box is fixedly arranged at the top of the base, a driving mechanism for rotating the placing table is arranged in the driving box, and the grab hand and sample injection needle integrated device is arranged at the top of the driving box; the driving mechanism comprises a first intermittent motor fixedly arranged in the driving box and a first rotating shaft rotatably arranged in the driving box and extending outside the driving box. This integrative device of tongs and application of sample needle for fluorescence immunoassay is through actuating mechanism, the integrative device of tongs and application of sample needle and adjustment mechanism, can be convenient carry out material loading and unloading, improves fluorescence immunoassay device's maintenance efficiency to reach the practicality and strong, advantage such as detection effect is good.
Description
Technical Field
The utility model relates to the technical field of immunofluorescence detection, in particular to a device integrating a handle and a sample adding needle for fluorescence immunoassay.
Background
The cell counting has important application in clinical diagnosis, food safety, environmental pollution monitoring and other aspects, and the immunofluorescence method is widely applied to cell counting, and the main principle is that a specific protein marker possibly exists on the surface of each cell, and fluorescent imaging of specific cells can be realized by staining an antibody marked by fluorescent dye corresponding to the marker, so that the cell counting can be realized by counting the number of fluorescent spots.
At present, when immunofluorescence is detected and analyzed, most of immunofluorescence samples are detected directly by workers, so that the efficiency is generally low, only a small amount of immunofluorescence can be detected, and work tasks cannot be completed timely or excessively. Through searching, prior art chinese patent CN216144669U discloses an immunofluorescence analysis apparatus, which comprises a substrate, wherein both sides of the upper surface of the substrate are fixed with upright posts, and top ends of the upright posts are fixed with top plates. This immunofluorescence analytical equipment can make the tray of its top circular motion through the fluted disc rotation to make the tray pass through first analysis appearance, make the last standing groove of tray in immunofluorescence sample accomplish the process of detecting analysis successfully, and the second analysis appearance that is located fluted disc lower surface also can be circular motion simultaneously, thereby make the second analysis appearance detect the analysis to immunofluorescence sample on the tray of layer board top, this immunofluorescence analytical equipment has realized detecting a plurality of samples simultaneously, and need not carry out manual operation, saved the labour, very big improvement work efficiency.
However, the immunofluorescence analysis device is inconvenient for feeding and discharging, the reagents are required to be placed on the tray one by one in a manual mode during feeding, and meanwhile, after detection is finished, test pieces on the tray are required to be discharged one by one, so that the analysis efficiency of the immunofluorescence analysis device is seriously affected, the production requirement cannot be met, and the problem in the prior art is solved by providing the integrated device of the handle and the sample adding needle for the immunofluorescence analysis.
Disclosure of Invention
Aiming at the defects of the prior art, the utility model provides a device integrating a handle and a sample adding needle for fluorescence immunoassay, which has the advantages of strong practicability, good detection effect and the like, and solves the problems that the existing immunofluorescence analysis device is inconvenient to feed and discharge so as to not meet the production requirement.
In order to achieve the above purpose, the present utility model provides the following technical solutions: the utility model provides a fluorescent immunoassay is with tongs and integrative device of application of sample needle, includes base, fixed mounting in riser at base top, fixed mounting in outside positive PLC controller and the analysis appearance of riser, the top of base is equipped with places the platform, and places the top demountable installation of platform and have the tray, the top fixed mounting of base has the drive case, the inside of drive case is equipped with the rotatory actuating mechanism to placing the platform, the top of drive case is equipped with tongs and integrative device of application of sample needle;
the driving mechanism comprises a first intermittent motor fixedly arranged in the driving box, a first rotating shaft rotatably arranged in the driving box and extending to the outside, a transmission gear fixedly arranged on an output shaft of the first intermittent motor, and a driven gear fixedly arranged outside the first rotating shaft and meshed with the transmission gear;
the integrated device of the tongs and the sample adding needle comprises the sample adding needle, a pump body, an electric push rod and an electric clamping jaw, wherein the electric clamping jaw is fixedly arranged at the output end of the electric push rod, the number of the pump bodies in the integrated device of the tongs and the sample adding needle is two, and the two pump bodies are distributed on the left side and the right side of the sample adding needle.
Further, the number of placing tables is two, and two placing tables are longitudinally and fixedly arranged outside the first rotating shaft, the number of the trays is a plurality of, and the plurality of trays are uniformly distributed at the edges of the two placing tables in an annular shape.
Further, the right side of riser fixedly welded has the crossbeam, the quantity of analysis appearance is two, and two analysis appearance respectively fixed mounting in the bottom of crossbeam and top place the platform.
Further, the regulating mechanism extends to the outside of the inside of the driving box and comprises a second intermittent motor fixedly arranged in the driving box, a second rotating shaft rotatably arranged in the driving box and extending to the outside of the driving box and rotationally connected with the bottom of the cross beam, a main bevel gear fixedly arranged on an output shaft of the second intermittent motor and a secondary bevel gear fixedly arranged outside the second rotating shaft and meshed with the main bevel gear.
Further, the outside fixed mounting of second axis of rotation has the mounting panel, application of sample needle and electric putter all with the inside fixed connection of mounting panel, pump body fixed mounting is in the top of mounting panel.
Further, the number of the mounting plates and the integral devices of the grippers and the sample adding needles is two, the two mounting plates are distributed outside the second rotating shaft up and down, and the two integral devices of the grippers and the sample adding needles are respectively arranged on the two mounting plates.
Further, the analyzer and the sample adding needle are both positioned above the tray, and the first rotating shaft and the second rotating shaft are both connected with the bearing of the driving box.
Further, the two pump bodies are respectively a positive pressure pump and a negative pressure pump, and the first rotating shaft penetrates through the middle of the placing table and is kept fixed with the placing table.
Compared with the prior art, the utility model provides a device integrating a handle and a sample adding needle for fluorescence immunoassay, which has the following beneficial effects:
1. this integrative device of tongs and application of sample needle for fluorescence immunoassay is through actuating mechanism, tongs and integrative device of application of sample needle and adjustment mechanism, can be convenient carry out material loading and unloading, improves fluorescence immunoassay device's maintenance efficiency to reach advantages such as the practicality is strong, and detection effect is good, has solved current immunofluorescence analysis device and has not been convenient for material loading and unloading, so that can not satisfy the problem of production demand.
2. This fluorescent immunoassay is with tongs and integrative device of application of sample needle uses through the exchange of two pump bodies, be convenient for drop the reagent of application of sample needle inside on a plurality of trays, thereby be convenient for carry out the material loading to a plurality of trays, after detecting, start the rotation of second intermittent motor drive main bevel gear, main bevel gear rotates and drives the mounting panel through the secondary bevel gear meshing and rotate, with electronic clamping jaw displacement to tray top, through the collocation use of electric putter and electronic clamping jaw, can improve unloading efficiency, realize the effect of being convenient for go up the unloading.
Drawings
FIG. 1 is a cross-sectional view of the structure of the present utility model;
FIG. 2 is a front elevational view of the structure of the present utility model;
FIG. 3 is a schematic view of the device integrating the gripper and the sample adding needle.
In the figure: 1 base, 2 risers, 3 crossbeams, 4PLC controllers, 5 placing tables, 6 trays, 7 analyzers, 8 driving boxes, 9 first intermittent motors, 10 first rotating shafts, 11 transmission gears, 12 driven gears, 13 sample adding needles, 14 pump bodies, 15 electric push rods, 16 electric clamping jaws, 17 second intermittent motors, 18 second rotating shafts, 181 mounting plates, 19 main bevel gears and 20 auxiliary bevel gears.
Detailed Description
The following description of the embodiments of the present utility model will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present utility model, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the utility model without making any inventive effort, are intended to be within the scope of the utility model.
Referring to fig. 1-3, a device integrating a gripper and a sample injection needle for fluorescence immunoassay comprises a base 1, a vertical plate 2 fixedly installed at the top of the base 1, a PLC controller 4 fixedly installed at the front surface of the outside of the vertical plate 2 and an analyzer 7, wherein a placing table 5 is arranged at the top of the base 1, a tray 6 is detachably installed at the top of the placing table 5, a driving box 8 is fixedly installed at the top of the base 1, the number of the placing tables 5 is two, the two placing tables 5 are longitudinally and fixedly installed at the outside of a first rotating shaft 10, the number of the trays 6 is multiple, and the trays 6 are uniformly distributed at the edges of the two placing tables 5 in an annular shape.
Wherein, the right side fixed welding of riser 2 has crossbeam 3, and the quantity of analysis appearance 7 is two, and two analysis appearance 7 fixed mounting respectively in the bottom of crossbeam 3 and top place platform 5. Through a plurality of trays 6 and two analyzers 7, can detect a plurality of samples simultaneously, and need not carry out manual operation, save the labour, very big improvement work efficiency.
And, the first rotation shaft 10 penetrates through the middle of the placement stage 5 and remains fixed thereto. The bottom fixed mounting of platform 5 is placed to the bottom has the gag lever post with drive box 8 sliding connection, and the quantity of gag lever post is two, and two gag lever posts symmetric distribution, through the setting of two gag lever posts, has guaranteed to place the stable rotation of platform 5, improves the detection effect.
In this embodiment, a driving mechanism for rotating the placement table 5 is provided inside the driving case 8, and the driving mechanism includes a first intermittent motor 9 fixedly installed inside the driving case 8, a first rotating shaft 10 rotatably installed inside the driving case 8 and extending to the outside thereof, a transmission gear 11 fixedly installed on an output shaft of the first intermittent motor 9, and a driven gear 12 fixedly installed outside the first rotating shaft 10 and meshed with the transmission gear 11.
In the embodiment, a gripper and a sample adding needle integrated device is arranged at the top of the driving box 8; the integrated device of the hand grip and the sample injection needle comprises a sample injection needle 13, a pump body 14, an electric push rod 15 and an electric clamping jaw 16, wherein the electric clamping jaw 16 is fixedly arranged at the output end of the electric push rod 15, the number of the pump bodies 14 in the integrated device of the hand grip and the sample injection needle is two, and the two pump bodies 14 are distributed on the left side and the right side of the sample injection needle 13. The two pump bodies 14 are respectively a positive pressure pump and a negative pressure pump.
It can be understood that the first intermittent motor 9 can be started by the PLC controller 4, so that the output shaft of the first intermittent motor drives the transmission gear 11 to be meshed with the driven gear 12, and drives the placement table 5 to rotate by the first rotating shaft 10, and then the reagent in the sample injection needle is dripped on the plurality of trays 6 by the exchange use of the two pump bodies 14, so that the plurality of trays 6 are conveniently fed. Through programming PLC controller 4, be convenient for effectively use the electrical apparatus of device, improve detection efficiency.
In this embodiment, the adjusting mechanism of the driving box 8 extending to the outside thereof includes a second intermittent motor 17 fixedly installed inside the driving box 8, a second rotating shaft 18 rotatably installed inside the driving box 8 and extending to the outside thereof to be rotatably connected with the bottom of the cross beam 3, a main bevel gear 19 fixedly installed at the output shaft of the second intermittent motor 17, and a sub bevel gear 20 fixedly installed at the outside of the second rotating shaft 18 and engaged with the main bevel gear 19. After the detection is finished, the second intermittent motor 17 is started to drive the main bevel gear 19 to rotate, the main bevel gear 19 rotates to be meshed with the auxiliary bevel gear 20 and drives the mounting plate 181 to rotate through the second rotating shaft 18, the electric clamping jaw 16 is displaced to the upper portion of the tray 6, and the electric clamping jaw 16 is matched with the electric push rod 15 to be used, so that the feeding is facilitated.
And, the distribution of the motorized clamping jaws 16 is adapted to the distribution of the trays 6. The telescopic distance of the electric push rod 15 is matched with the distribution height of the tray 6.
Wherein, the outside fixed mounting of second axis of rotation 18 has mounting panel 181, and application of sample needle 13 and electric putter 15 all with the inside fixed connection of mounting panel 181, pump body 14 fixed mounting is in the top of mounting panel 181. The number of the mounting plates 181 and the number of the integrated devices of the grippers and the sample adding needles are two, the two mounting plates 181 are distributed outside the second rotating shaft 18 up and down, and the two integrated devices of the grippers and the sample adding needles are respectively arranged on the two mounting plates 181.
The analyzer 7 and the sample loading needle 13 are both positioned above the tray 6, and the first rotation shaft 10 and the second rotation shaft 18 are both bearing-connected to the drive box 8. The outside of the sample adding needle 13 is fixedly communicated with a communicating pipe which is fixed with the pump body 14.
It should be noted that, the analyzer, the sample adding needle and the electric clamping jaw all belong to the conventional technology known to the public in the prior art, so that the specific structural composition and the working principle thereof are not repeated herein.
The working principle of the embodiment is as follows:
the first intermittent motor 9 can be started to drive the transmission gear 11 to be meshed with the driven gear 12 through the PLC 4, the placing table 5 is driven to rotate through the first rotating shaft 10, then reagents inside the sample adding needle are dripped on the trays 6 through the exchange of the two pump bodies 14, after detection is finished, the second intermittent motor 17 is started to drive the main bevel gear 19 to rotate, the main bevel gear 19 is meshed with the auxiliary bevel gear 20 in a rotating mode, the mounting plate 181 is driven to rotate through the second rotating shaft 18, the electric clamping jaw 16 is moved to the upper portion of the tray 6, and the electric clamping jaw 16 is matched with the electric push rod 15 to be used, so that discharging is facilitated.
The beneficial effects of the embodiment are as follows:
this fluorescent immunoassay is with tongs and integrative device of application of sample needle, can start first intermittent motor 9 through PLC controller 4, make its output shaft drive transmission gear 11 and driven gear 12 meshing and drive through first axis of rotation 10 and place the platform 5 rotation, then through the exchange use of two pump bodies 14, drop the reagent of application of sample needle 13 inside on a plurality of trays 6, thereby be convenient for carry out the material loading to a plurality of trays 6, after detecting, start second intermittent motor 17 and drive main bevel gear 19 rotatory, main bevel gear 19 rotates and drives the mounting panel 181 rotation through second axis of rotation 18 with vice bevel gear 20 meshing, with electric jaw 16 displacement to tray 6 top, through the collocation use of electric putter 15 and electric jaw 16, the unloading of being convenient for, effectively solved the problem that current immunofluorescence analytical device is inconvenient for material loading and unloading, so as to not to satisfy the production demand.
The electrical components appearing herein are all electrically connected with the master controller and the power supply, the master controller can be a conventional known device for controlling a computer and the like, and the prior art of power connection is not described in detail herein.
It is noted that relational terms such as first and second, and the like are used solely to distinguish one entity or action from another entity or action without necessarily requiring or implying any actual such relationship or order between such entities or actions. Moreover, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus. Without further limitation, an element defined by the phrase "comprising one … …" does not exclude the presence of other like elements in a process, method, article, or apparatus that comprises the element.
Although embodiments of the present utility model have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made therein without departing from the principles and spirit of the utility model, the scope of which is defined in the appended claims and their equivalents.
Claims (8)
1. The utility model provides a fluorescent immunoassay is with tongs and integrative device of application of sample needle, includes base (1), fixed mounting in riser (2) at base (1) top, fixed mounting in outside positive PLC controller (4) and analyzer (7) of riser (2), its characterized in that: the top of the base (1) is provided with a placing table (5), the top of the placing table (5) is detachably provided with a tray (6), the top of the base (1) is fixedly provided with a driving box (8), a driving mechanism for rotating the placing table (5) is arranged in the driving box (8), and the top of the driving box (8) is provided with a gripper and sample adding needle integrated device;
the driving mechanism comprises a first intermittent motor (9) fixedly arranged in the driving box (8), a first rotating shaft (10) rotatably arranged in the driving box (8) and extending to the outside, a transmission gear (11) fixedly arranged on the output shaft of the first intermittent motor (9) and a driven gear (12) fixedly arranged outside the first rotating shaft (10) and meshed with the transmission gear (11);
the integrated device of the tongs and the sample adding needle comprises the sample adding needle (13), a pump body (14), an electric push rod (15) and an electric clamping jaw (16), wherein the electric clamping jaw (16) is fixedly arranged at the output end of the electric push rod (15), the number of the pump bodies (14) in the integrated device of the tongs and the sample adding needle is two, and the two pump bodies (14) are distributed on the left side and the right side of the sample adding needle (13).
2. The integrated fluoroimmunoassay gripper and sample addition needle device of claim 1, wherein: the number of the placing tables (5) is two, the two placing tables (5) are longitudinally and fixedly arranged outside the first rotating shaft (10), the number of the trays (6) is multiple, and the trays (6) are uniformly distributed at the edges of the two placing tables (5) in an annular shape.
3. The integrated fluoroimmunoassay gripper and sample addition needle device of claim 1, wherein: the right side of riser (2) fixedly welded has crossbeam (3), the quantity of analysis appearance (7) is two, and two analysis appearance (7) fixed mounting respectively in the bottom of crossbeam (3) and top place platform (5).
4. A fluorescence immunoassay gripping and needle integrated device of claim 3, wherein: the adjusting mechanism comprises a second intermittent motor (17) fixedly arranged in the driving box (8), a second rotating shaft (18) rotatably arranged in the driving box (8) and extending to the outside and rotationally connected with the bottom of the cross beam (3), a main bevel gear (19) fixedly arranged on an output shaft of the second intermittent motor (17), and a secondary bevel gear (20) fixedly arranged outside the second rotating shaft (18) and meshed with the main bevel gear (19).
5. The integrated fluoroimmunoassay gripper and sample addition needle device of claim 4, wherein: the outside fixed mounting of second axis of rotation (18) has mounting panel (181), application of sample needle (13) and electric putter (15) all with the inside fixed connection of mounting panel (181), pump body (14) fixed mounting is in the top of mounting panel (181).
6. The integrated fluoroimmunoassay gripper and sample addition needle device of claim 5, wherein: the number of the mounting plates (181) and the number of the devices integrating the grippers and the sample adding needles are two, the two mounting plates (181) are distributed outside the second rotating shaft (18) up and down, and the two devices integrating the grippers and the sample adding needles are respectively arranged on the two mounting plates (181).
7. The integrated fluoroimmunoassay gripper and sample addition needle device of claim 1, wherein: the analyzer (7) and the sample adding needle (13) are both positioned above the tray (6), and the first rotating shaft (10) and the second rotating shaft (18) are both connected with the bearing of the driving box (8).
8. The integrated fluoroimmunoassay gripper and sample addition needle device of claim 1, wherein: the two pump bodies (14) are respectively a positive pressure pump and a negative pressure pump, and the first rotating shaft (10) penetrates through the middle of the placing table (5) and is kept fixed with the placing table.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202320941174.2U CN219831113U (en) | 2023-04-24 | 2023-04-24 | Fluorescent immunoassay is with tongs and integrative device of application of sample needle |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202320941174.2U CN219831113U (en) | 2023-04-24 | 2023-04-24 | Fluorescent immunoassay is with tongs and integrative device of application of sample needle |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN219831113U true CN219831113U (en) | 2023-10-13 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202320941174.2U Active CN219831113U (en) | 2023-04-24 | 2023-04-24 | Fluorescent immunoassay is with tongs and integrative device of application of sample needle |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN219831113U (en) |
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- 2023-04-24 CN CN202320941174.2U patent/CN219831113U/en active Active
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