CN219701954U - Eight-head cup separating machine convenient for uncapping, pipetting and capping operation - Google Patents
Eight-head cup separating machine convenient for uncapping, pipetting and capping operation Download PDFInfo
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- CN219701954U CN219701954U CN202321113933.2U CN202321113933U CN219701954U CN 219701954 U CN219701954 U CN 219701954U CN 202321113933 U CN202321113933 U CN 202321113933U CN 219701954 U CN219701954 U CN 219701954U
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- 238000005070 sampling Methods 0.000 claims abstract description 61
- 238000012360 testing method Methods 0.000 claims abstract description 24
- 239000007788 liquid Substances 0.000 claims abstract description 23
- 230000009471 action Effects 0.000 claims description 18
- 238000009434 installation Methods 0.000 claims description 8
- 239000003638 chemical reducing agent Substances 0.000 claims description 7
- 210000000078 claw Anatomy 0.000 claims description 7
- 230000001360 synchronised effect Effects 0.000 claims description 6
- 238000012546 transfer Methods 0.000 abstract description 10
- 239000003153 chemical reaction reagent Substances 0.000 abstract description 6
- 238000000605 extraction Methods 0.000 abstract description 4
- 150000007523 nucleic acids Chemical group 0.000 description 10
- 102000039446 nucleic acids Human genes 0.000 description 9
- 108020004707 nucleic acids Proteins 0.000 description 9
- 238000003745 diagnosis Methods 0.000 description 7
- 238000000034 method Methods 0.000 description 6
- 238000000338 in vitro Methods 0.000 description 4
- 238000003752 polymerase chain reaction Methods 0.000 description 4
- 238000010586 diagram Methods 0.000 description 3
- 238000007599 discharging Methods 0.000 description 3
- 239000002699 waste material Substances 0.000 description 3
- 238000012408 PCR amplification Methods 0.000 description 2
- 230000003321 amplification Effects 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- 208000015181 infectious disease Diseases 0.000 description 2
- 238000003199 nucleic acid amplification method Methods 0.000 description 2
- 239000011148 porous material Substances 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 208000026350 Inborn Genetic disease Diseases 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000010170 biological method Methods 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 238000003759 clinical diagnosis Methods 0.000 description 1
- 208000016361 genetic disease Diseases 0.000 description 1
- 238000005213 imbibition Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000003793 prenatal diagnosis Methods 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 230000010076 replication Effects 0.000 description 1
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Abstract
The utility model relates to the technical field of sample extraction devices, in particular to an eight-head cup separating machine convenient for uncapping, pipetting and capping operations, which comprises a working platform, wherein a sampling tube uncapping module, a pipetting module, a test tube rack module, a sampling tube bottom clamping module, a sample carrier module, a sampling head module and a needle removing module are arranged on the working platform. In this eight cup machines that divide convenient to uncap liquid transfer closes lid operation, can replace the manual work to accomplish the transfer of liquid reagent and sample extract, promote the transfer efficiency of liquid reagent and sample extract, liberated laboratory staff's both hands, can realize that the test tube is uncapped automatically, the pipetting, close the machine automation of work such as lid and accomplish. The sampling tube is conveyed to the uncapping position from the test tube rack module through the sampling tube uncapping module, so that automatic uncapping is realized. The automatic liquid suction is ensured after the automatic suction head is automatically opened through the liquid suction module, and the sampling tube is conveniently clamped and placed by the sampling tube conveying module through the sampling tube fixing module.
Description
Technical Field
The utility model relates to the technical field of sample extraction devices, in particular to an eight-head cup separating machine convenient for opening and closing a cover.
Background
In vitro diagnosis is an important component in clinical medicine, and the molecular diagnosis covered by in vitro diagnosis is an indispensable part in clinical medicine. Molecular diagnosis refers to a technique for diagnosing by detecting the change of the structure or expression level of genetic material in a patient by using a molecular biological method, and is a main method for predictive diagnosis, and can be used for diagnosing individual genetic diseases or prenatal diagnosis. The Polymerase Chain Reaction (PCR) is a molecular biological technique for amplifying specific nucleic acid fragments, and can be regarded as specific nucleic acid replication in vitro, and the greatest feature of PCR is that it can greatly increase the trace amount of nucleic acid. Therefore, the molecular diagnosis technology based on the PCR technology is widely applied to in vitro clinical diagnosis.
Before molecular diagnosis, firstly extracting nucleic acid from a sample, transferring the sample from a sample tube to a deep hole plate, transferring the deep hole plate to a nucleic acid extraction instrument for extracting nucleic acid, transferring a nucleic acid extracting solution to an octant after completing nucleic acid extraction, and then placing the octant into a PCR amplification instrument for amplification and interpretation. At present, the transfer of a sample into a deep pore plate and the transfer of a nucleic acid extracting solution into an octagon tube are both performed manually, so that the efficiency is low, and a certain risk of infection and reagent pollution exists through manual operation.
Disclosure of Invention
The utility model aims to provide an eight-head cup separating machine convenient for uncapping, pipetting and uncapping operation, which solves the problems that the transfer of a sample into a deep pore plate and the transfer of a nucleic acid extracting solution into an eight-connecting tube are manually operated at present in the background art, the efficiency is low, and a certain risk of infection and reagent pollution exists through manual operation.
In order to achieve the above purpose, the utility model provides an eight-head cup separating machine convenient for uncapping, pipetting and capping operations, which comprises a working platform, wherein a sampling tube uncapping module, a pipetting module, a test tube rack module, a sampling tube bottom clamping module, a sample carrier module, a sampling head module and a needle removing module are arranged on the working platform, the sampling tube uncapping module comprises a platform, sampling tube clamping jaws are arranged on the platform, the sampling tube clamping jaws comprise a sampling tube cover clamping jaw body and a cover clamping jaw rotating head, the cover clamping jaw rotating head comprises a linear motor and a rotating motor, a proximity switch is arranged at the top of the linear motor, a linear motor push rod is arranged at an output shaft of the linear motor, an air jaw installation shaft is arranged at the bottom of the linear motor push rod, a clamping jaw clamping action shaft is arranged at the bottom of the air jaw installation shaft, and a first clamping jaw is arranged on the clamping jaw clamping action shaft.
Preferably, one side of a platform of the sampling tube uncapping module is provided with an X-direction transportation module, the other side of the platform is provided with a Y-direction transportation module, and the middle part of the platform is provided with a Z-direction transportation module.
Preferably, a first groove-shaped switch is arranged in the middle of the linear motor, a first driving wheel is arranged on an output shaft of the rotary motor, and the first driving wheel is connected with a first driven wheel through a first synchronous belt.
Preferably, the X-direction transportation module comprises an X-direction motor, a speed reducer is installed on an output shaft of the X-direction motor, a second driving wheel is installed at an output end of the speed reducer, and the second driving wheel is connected with a second driven wheel through a second synchronous belt.
Preferably, the Y-direction transportation module comprises a Y-direction motor, an output shaft of the Y-direction motor drives the test tube rack module to linearly move through a screw rod, one end of the screw rod is supported and fixed through a motor supporting piece, guide rails are arranged on two sides of the Y-direction motor, and the bottom of the test tube rack module slides along the guide rails.
Preferably, the Z-direction transportation module comprises a Z-direction motor, a screw rod assembly is mounted on an output shaft of the Z-direction motor, and the screw rod assembly can drive the sampling tube bottom clamping module to linearly move.
Preferably, the sampling tube bottom clamping module comprises a screw motor, a second groove-shaped switch is arranged at the top of the screw motor, a clamping jaw action shaft is arranged on an output shaft of the screw motor through a linear bearing, a horizontal clamping jaw is arranged on the clamping jaw action shaft, a second clamping jaw is arranged at the top of the horizontal clamping jaw, a reflection sensor is arranged at the top of the second clamping jaw, the second clamping jaw clamps and fixes a test tube, and a spring is arranged at the bottom of the clamping jaw action shaft.
Preferably, the bottom of the sampling head module is provided with a linear guide rail, spring pieces are arranged on two sides of the linear guide rail, one end of the linear guide rail is provided with a magnet, the needle removing head module comprises a needle removing plate, and the bottom of the needle removing plate is provided with a discharging hopper.
Compared with the prior art, the utility model has the beneficial effects that:
1. in this eight cup machines that divide convenient to uncap liquid transfer closes lid operation, can replace the manual work to accomplish the transfer of liquid reagent and sample extract, promote the transfer efficiency of liquid reagent and sample extract, liberated laboratory staff's both hands, can realize that the test tube is uncapped automatically, the pipetting, close the machine automation of work such as lid and accomplish.
2. In this eight cup separating machine convenient to uncap pipetting closes lid operation, transport the sampling pipe from test-tube rack module to uncap the position through sampling pipe uncapping module, realize automatic uncapping.
3. In this eight cup separator convenient to uncap pipetting closes lid operation, guarantee through pipetting module that automatic imbibition after automatic suction head of getting after test tube lid is opened by the automation, make things convenient for sampling tube transport module clamp to get and place the sampling tube through sampling tube fixed module.
Drawings
FIG. 1 is an assembly drawing of the whole machine of the present utility model;
FIG. 2 is a schematic view of a sample tube uncap module according to the present utility model;
FIG. 3 is a schematic structural view of an X-direction transport module according to the present utility model;
FIG. 4 is a schematic diagram of a feeding state of a Y-direction transport module according to the present utility model;
FIG. 5 is a schematic diagram showing the working state of the Y-direction transport module according to the present utility model;
FIG. 6 is a schematic view of a Z-direction transport module according to the present utility model;
FIG. 7 is a schematic view showing the structure of a clamping module at the bottom of a sampling tube according to the present utility model
FIG. 8 is a cross-sectional view of a sample tube bottom clamping module of the present utility model;
FIG. 9 is a schematic view of a sample tube jaw-cap jaw swivel head in accordance with the present utility model;
FIG. 10 is a cross-sectional view of a sample tube jaw-cap jaw swivel head of the present utility model;
FIG. 11 is a schematic diagram of the loading state of the sample carrier module and the sampling head module according to the present utility model;
FIG. 12 is a schematic view of the sample carrier module and the sampling head module according to the present utility model;
fig. 13 is a schematic view of a needle-removing module according to the present utility model.
The meaning of each reference sign in the figure is:
1. a sampling tube uncapping module; 11. a sampling tube cap jaw body; 12. a cover jaw swivel; 121. a proximity switch; 122. a linear motor; 123. a rotating electric machine; 124. a first slot type switch; 125. a first driven wheel; 126. a first synchronization belt; 127. a first drive wheel; 128. a gas claw; 129. a first jaw; 1210. a linear motor push rod; 1211. a gas claw mounting shaft; 1212. a clamping jaw clamping action shaft; 13. an X-direction transportation module; 131. an X-direction motor; 132. a speed reducer; 133. a second driving wheel; 134. a second driven wheel; 135. a second timing belt; 14. a Y-direction transportation module; 141. a Y-direction motor; 142. a motor support; 143. a guide rail; 15. a Z-direction transportation module; 151. a Z-direction motor; 152. a screw assembly; 2. a pipetting module; 3. a test tube rack module; 4. a clamping module at the bottom of the sampling tube; 41. a screw motor; 42. a second slot type switch; 43. a linear bearing; 44. a horizontal clamping jaw; 45. a second jaw; 46. a reflective sensor; 47. a spring; 48. a jaw actuation shaft; 49. a test tube; 5. a sample carrier module; 6. a sampling head module; 61. a spring piece; 62. a linear guide rail; 63. a magnet; 7. a needle removing module; 71. a faller; 72. and (5) discharging a hopper.
Detailed Description
The following description of the embodiments of the present utility model will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present utility model, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the utility model without making any inventive effort, are intended to be within the scope of the utility model.
The utility model provides an eight-head cup separating machine convenient for uncapping, pipetting and uncapping operations, which is shown in fig. 1-13 and comprises a working platform, wherein a sampling tube uncapping module 1, a pipetting module 2, a test tube rack module 3, a sampling tube bottom clamping module 4, a sample carrier module 5, a sampling head module 6 and a needle removing module 7 are arranged on the working platform, the sampling tube uncapping module 1 comprises a platform, sampling tubes are conveyed from the test tube rack module 3 to an uncapping position to realize automatic uncapping, sampling tube clamping jaws are arranged on the platform, each sampling tube clamping jaw comprises a sampling tube cover clamping jaw body 11 and a cover clamping jaw rotating head 12, one side of the platform is provided with an X-direction conveying module 13, the other side of the platform is provided with a Y-direction conveying module 14, and the middle part of the platform is provided with a Z-direction conveying module 15 to realize conveying operations in different directions.
In this embodiment, the cover jaw rotating head 12 includes a linear motor 122 and a rotating motor 123, a proximity switch 121 is installed at the top of the linear motor 122, a linear motor push rod 1210 is installed at the output shaft of the linear motor 122, a gas jaw installation shaft 1211 is provided at the bottom end of the linear motor push rod 1210, a jaw clamping action shaft 1212 is provided at the bottom of the gas jaw installation shaft 1211, a gas jaw 128 is installed on the gas jaw installation shaft 1211, and a first jaw 129 is installed on the jaw clamping action shaft 1212 for clamping the cover for rotating operation.
Specifically, a first groove-shaped switch 124 is installed in the middle of the linear motor 122, a first driving wheel 127 is installed on an output shaft of the rotating motor 123, the first driving wheel 127 is connected with a first driven wheel 125 through a first synchronous belt 126, the first driving wheel 127 is driven to rotate through the rotating motor 123, and then the first clamping jaw 129 is driven to rotate.
Further, the X-direction transportation module 13 includes an X-direction motor 131, a speed reducer 132 is installed on an output shaft of the X-direction motor 131, a second driving wheel 133 is installed at an output end of the speed reducer 132, the second driving wheel 133 is connected with a second driven wheel 134 through a second synchronous belt 135, and the apparatus is driven to horizontally move through the X-direction motor 131.
Further, the Y-direction transporting module 14 includes a Y-direction motor 141, an output shaft of the Y-direction motor 141 drives the test tube rack module 3 to linearly move through a screw rod, one end of the screw rod is supported and fixed through a motor supporting piece 142, guide rails 143 are installed on two sides of the Y-direction motor 141, and the bottom of the test tube rack module 3 slides along the guide rails 143.
Further, the Z-direction transportation module 15 comprises a Z-direction motor 151, a screw rod assembly 152 is installed on an output shaft of the Z-direction motor 151, and the screw rod assembly 152 can drive the sampling tube bottom clamping module 4 to linearly move.
Further, the sampling tube bottom clamping module 4 comprises a screw motor 41, a second groove-shaped switch 42 is arranged at the top of the screw motor 41, a clamping jaw action shaft 48 is arranged on an output shaft of the screw motor 41 through a linear bearing 43, a horizontal clamping jaw 44 is arranged on the clamping jaw action shaft 48, a second clamping jaw 45 is arranged at the top of the horizontal clamping jaw 44, a reflection sensor 46 is arranged at the top of the second clamping jaw 45, a test tube 49 is clamped and fixed by the second clamping jaw 45, and a spring 47 is arranged at the bottom of the clamping jaw action shaft 48.
Further, a linear guide rail 62 is installed at the bottom of the sampling head module 6, and spring pieces 61 are installed at both sides of the linear guide rail 62.
Further, a magnet 63 is attached to one end of the linear guide 62.
Further, the needle removing module 7 comprises a needle removing plate 71, and a discharging hopper 72 is arranged at the bottom of the needle removing plate 71.
When the eight-head cup separating machine convenient for cover opening, liquid transferring and cover closing operation is used, firstly, a sampling tube which is needed is placed into a test tube rack module 3 before an experiment is carried out, the test tube rack module 3 is placed onto a clamping module 4 at the bottom of the sampling tube, then a 96 deep hole plate is placed onto a liquid transferring module 2, then a sampling head module 6 with a sampling head is placed onto a base of the sampling head module 6, a spring piece 61 can clamp and position a test tube 49 to avoid shaking in the transferring process, meanwhile, the positioning precision of the liquid transferring module 2 in the liquid transferring process is ensured, after the test tube rack module 3 is placed, the liquid transferring module 2 acquires the sampling head from the sampling head module 6 and then moves to the upper side of the test tube rack module 3, samples are sucked from corresponding sampling tubes and distributed into a 96 deep hole plate, then the liquid transferring module 2 moves to the upper side of a waste needle box, a needle removing module 7 is used for needle removing, a waste sample needle falls into the waste needle box from a blanking hopper 72, sample liquid transferring is completed, and then the 96 plate is transferred into a PCR amplification judging instrument for amplification.
Finally, it should be noted that, in the present embodiment, the linear motor 122, the rotary motor 123, the air claw 128, the linear motor push rod 1210, the X-direction motor 131, the Y-direction motor 141, the Z-direction motor 151, etc., all the electronic components in the above components are common standard components or components known to those skilled in the art, the structure and principle thereof are all known by those skilled in the art through technical manuals or known through routine experiment methods, at the idle position of the present device, all the above electrical components are connected through wires, and the specific connection means should refer to the sequential working order among the electrical components in the working principle to complete the electrical connection, which is known in the art.
The foregoing has shown and described the basic principles, principal features and advantages of the utility model. It will be understood by those skilled in the art that the present utility model is not limited to the above-described embodiments, and that the above-described embodiments and descriptions are only preferred embodiments of the present utility model, and are not intended to limit the utility model, and that various changes and modifications may be made therein without departing from the spirit and scope of the utility model as claimed. The scope of the utility model is defined by the appended claims and equivalents thereof.
Claims (8)
1. Eight cup machines that divide are convenient for uncap move liquid and close lid operation, including work platform, its characterized in that: be provided with sampling tube module (1) of uncapping on the work platform, pipetting module (2), test-tube rack module (3), sampling tube bottom clamp module (4), sample carrier module (5), sampling head module (6) and take off syringe needle module (7), sampling tube module (1) of uncapping includes the platform, is provided with sampling tube clamping jaw on the platform, and sampling tube clamping jaw includes sampling tube lid clamping jaw body (11) and lid clamping jaw rotating head (12), lid clamping jaw rotating head (12) include linear motor (122), rotating electrical machines (123), proximity switch (121) are installed at the top of linear motor (122), linear motor push rod (1210) are installed to the output shaft of linear motor (122), the bottom of linear motor push rod (1210) is provided with gas claw installation axle (1211), the bottom of gas claw installation axle (1211) is provided with clamp action axle (1212), install gas claw (128) on gas claw installation axle (1211), install first clamping jaw (129) on clamp action axle (1212).
2. The eight-head cup dispenser facilitating cover opening, liquid transferring and closing operation according to claim 1, wherein: an X-direction transportation module (13) is arranged on one side of a platform of the sampling tube uncapping module (1), a Y-direction transportation module (14) is arranged on the other side of the platform, and a Z-direction transportation module (15) is arranged in the middle of the platform.
3. The eight-head cup dispenser facilitating cover opening, liquid transferring and closing operation according to claim 1, wherein: the middle part of linear electric motor (122) is installed first groove type switch (124), first action wheel (127) is installed to the output shaft of rotating electrical machines (123), first action wheel (127) are connected with first follow driving wheel (125) through first synchronous area (126).
4. The eight-head cup dispenser facilitating cover opening, liquid transferring and closing operation according to claim 2, wherein: the X-direction transportation module (13) comprises an X-direction motor (131), a speed reducer (132) is installed on an output shaft of the X-direction motor (131), a second driving wheel (133) is installed at an output end of the speed reducer (132), and the second driving wheel (133) is connected with a second driven wheel (134) through a second synchronous belt (135).
5. The eight-head cup dispenser facilitating cover opening, liquid transferring and closing operation according to claim 2, wherein: the Y-direction conveying module (14) comprises a Y-direction motor (141), an output shaft of the Y-direction motor (141) drives the test tube rack module (3) to linearly move through a screw rod, one end of the screw rod is supported and fixed through a motor supporting piece (142), guide rails (143) are arranged on two sides of the Y-direction motor (141), and the bottom of the test tube rack module (3) slides along the guide rails (143).
6. The eight-head cup dispenser facilitating cover opening, liquid transferring and closing operation according to claim 2, wherein: the Z-direction conveying module (15) comprises a Z-direction motor (151), a screw rod assembly (152) is mounted on an output shaft of the Z-direction motor (151), and the screw rod assembly (152) can drive the sampling tube bottom clamping module (4) to move linearly.
7. The eight-head cup dispenser facilitating cover opening, liquid transferring and closing operation according to claim 1, wherein: the sampling tube bottom clamping module (4) comprises a screw motor (41), a second groove-shaped switch (42) is arranged at the top of the screw motor (41), a clamping jaw action shaft (48) is arranged on an output shaft of the screw motor (41) through a linear bearing (43), a horizontal clamping jaw (44) is arranged on the clamping jaw action shaft (48), a second clamping jaw (45) is arranged at the top of the horizontal clamping jaw (44), a reflection sensor (46) is arranged at the top of the second clamping jaw (45), the second clamping jaw (45) clamps and fixes a test tube (49), and a spring (47) is arranged at the bottom of the clamping jaw action shaft (48).
8. The eight-head cup dispenser facilitating cover opening, liquid transferring and closing operation according to claim 1, wherein: the bottom of sampling head module (6) is installed linear guide (62), spring piece (61) are installed to the both sides of linear guide (62), magnet (63) are installed to the one end of linear guide (62), take off syringe needle module (7) including taking off faller (71), take off faller (71) bottom and install down hopper (72).
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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CN202321113933.2U CN219701954U (en) | 2023-05-10 | 2023-05-10 | Eight-head cup separating machine convenient for uncapping, pipetting and capping operation |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
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CN202321113933.2U CN219701954U (en) | 2023-05-10 | 2023-05-10 | Eight-head cup separating machine convenient for uncapping, pipetting and capping operation |
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CN219701954U true CN219701954U (en) | 2023-09-19 |
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CN202321113933.2U Active CN219701954U (en) | 2023-05-10 | 2023-05-10 | Eight-head cup separating machine convenient for uncapping, pipetting and capping operation |
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CN (1) | CN219701954U (en) |
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2023
- 2023-05-10 CN CN202321113933.2U patent/CN219701954U/en active Active
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