CN219526623U

CN219526623U - Harvesting device for chick embryo allantoic fluid

Info

Publication number: CN219526623U
Application number: CN202320583383.4U
Authority: CN
Inventors: 候进熙; 陈鑫; 张锦鹏
Original assignee: Guangzhou Sianxin Biotechnology Co ltd
Current assignee: Guangzhou Sianxin Biotechnology Co ltd
Priority date: 2023-03-21
Filing date: 2023-03-21
Publication date: 2023-08-15
Anticipated expiration: 2033-03-21

Abstract

The utility model relates to a harvesting device for chick embryo allantoic fluid, which comprises a straw; the silica gel sleeve is sleeved at one end of the suction pipe, and the suction pipe sucks liquid through the silica gel sleeve; the liquid suction mechanism is connected with one end of the suction pipe, which is far away from the silica gel sleeve; when the disposable diaper is used, the silica gel sleeve is placed in allantoic fluid of a chick embryo by the aid of the suction pipe, and the liquid suction mechanism drives the silica gel sleeve to suck the allantoic fluid through the suction pipe. Placing the silica gel sleeve in allantoic fluid of the chick embryo, and driving the silica gel sleeve to absorb the allantoic fluid by using a suction pipe by using a liquid suction mechanism so as to obtain the allantoic fluid; the liquid sucking mechanism is a suction machine or a peristaltic pump, and compared with the prior art, the efficiency of obtaining allantoic liquid is improved. The suction tube is a transparent glass tube, the glass tube can be sterilized by dry heat before use, the silica gel sleeve can also be sterilized by wet heat, and the whole harvesting device can be sterilized by sterilizing the liquid suction mechanism, so that the pollution of allantoic fluid during harvesting of the allantoic fluid is reduced.

Description

Harvesting device for chick embryo allantoic fluid

Technical Field

The utility model relates to the technical field of biological product production, in particular to a harvesting device for chick embryo allantoic fluid.

Background

In the production process of virus vaccines, because some viruses are sensitive to the expression of chick embryos, chick embryos are often utilized to proliferate the viruses so as to obtain the required antigen; chick embryos are infected with a susceptible virus, and then chick embryo allantoic fluid is harvested and cultured under appropriate conditions.

At present, chick embryo allantoic fluid is usually harvested by adopting a suction pipe, a syringe or a method of directly breaking a shell and pouring out the allantoic fluid, and as disclosed in the prior patent with publication number CN210886040U, the chick embryo allantoic fluid simple collecting device is easy to collect the allantoic fluid by manual operation through the syringe, has low working efficiency, is easy to cause cross contamination and has unstable product quality. In the large-scale production process, in order to improve efficiency and productivity, an automatic harvester is often used for harvesting chick embryo allantoic fluid, although the production efficiency is improved, the cost is high, the later maintenance of the automatic harvester is also complex, and the method for harvesting chick embryo allantoic fluid is often inapplicable to test production or research in the current period, is easy to increase project cost, and has poor practicability.

Disclosure of Invention

Based on this, it is an object of the present utility model to provide a harvesting device for chick embryo allantoic fluid, which has the advantage of improving the efficiency and quality of the harvested allantoic fluid.

The above object of the present utility model is achieved by the following technical solutions:

a harvesting device for chick embryo allantoic fluid, comprising:

a suction pipe;

the silica gel sleeve is sleeved at one end of the suction pipe, and the suction pipe sucks liquid through the silica gel sleeve;

the liquid suction mechanism is connected with one end of the suction pipe, which is far away from the silica gel sleeve;

when the disposable diaper is used, the silica gel sleeve is placed in allantoic fluid of a chick embryo by the aid of the suction pipe, and the liquid suction mechanism drives the silica gel sleeve to suck the allantoic fluid through the suction pipe.

The utility model is further provided with: one side of the silica gel sleeve is provided with a bulge for extruding the egg yolk sac of the chick embryo.

The utility model is further provided with: one end of the silica gel sleeve is provided with a honeycomb-shaped liquid suction hole for sucking liquid.

The utility model is further provided with: the liquid suction holes comprise honeycomb holes arranged at the end part of the silica gel sleeve and suction holes arranged on the peripheral wall of the silica gel sleeve.

The utility model is further provided with: the suction tube is a transparent glass tube.

The utility model is further provided with: the protrusions are translucent protrusions.

The utility model is further provided with: the liquid suction mechanism is a suction machine or a peristaltic pump.

In summary, the beneficial technical effects of the utility model are as follows:

the utility model provides a harvesting device for chick embryo allantoic fluid, when in use, a silica gel sleeve is arranged in the chick embryo allantoic fluid, and a liquid suction mechanism is utilized to drive the silica gel sleeve to suck the allantoic fluid through a suction pipe so as to obtain the allantoic fluid; the liquid sucking mechanism is a suction machine or a peristaltic pump, and compared with the prior art, the efficiency of obtaining allantoic liquid is improved. The suction tube is a transparent glass tube, the glass tube can be sterilized by dry heat before use, the silica gel sleeve can also be sterilized by wet heat, and the whole harvesting device can be sterilized by sterilizing the liquid suction mechanism, so that the pollution of allantoic fluid during harvesting of the allantoic fluid is reduced.

Because the suction tube is a transparent glass tube, when the allantoic fluid is harvested, the situation of the harvested fluid can be directly seen from the glass tube, such as the occurrence of chick embryo necrosis, egg yolk inhalation and the like, and subsequent measures can be timely found and taken to improve the quality of the harvested allantoic fluid. One end of the silica gel sleeve is provided with a honeycomb-shaped liquid suction hole, so that allantoic fluid can be absorbed conveniently, and the inner structure of the chick embryo is not easy to puncture by the silica gel sleeve in the collecting process; the imbibition hole is including setting up the honeycomb hole at silica gel cover tip and setting up the absorption hole at silica gel cover perisporium for the range of absorbing allantoic fluid expands to a plurality of absorption points from an absorption point, in order to form three-dimensional absorption range, and the allantoic fluid is contacted to the arbitrary position of silica gel cover one end, all can gather the allantoic fluid. The silica gel sleeve has a bulge structure with one side expanded, and the yolk sac is extruded by the bulge so as to increase the amount of allantoic fluid harvested.

For a better understanding and implementation, the present utility model is described in detail below with reference to the drawings.

Drawings

The drawings are for illustrative purposes only and are not to be construed as limiting the present patent; for the purpose of better illustrating the embodiments, certain elements of the drawings may be omitted, enlarged or reduced and do not represent the actual product dimensions; it will be appreciated by those skilled in the art that certain well-known structures in the drawings and descriptions thereof may be omitted.

FIG. 1 is a cross-sectional view of the harvesting apparatus of the present utility model when harvesting allantoic fluid.

FIG. 2 is a cross-sectional view of a straw and silicone sleeve of the present utility model.

In the figure, 1, a straw; 2. a silica gel sleeve; 21. a protrusion; 22. a liquid suction hole; 221. honeycomb holes; 222. a suction hole; 3. eggshells; 4. chicken embryo body; 5. yolk sac body; 6. allantois; 7. egg white.

Detailed Description

Terms of orientation such as up, down, left, right, front, rear, front, back, top, bottom, etc. mentioned or possible mentioned in this specification are defined with respect to their construction, and they are relative concepts. Therefore, the position and the use state of the device may be changed accordingly. These and other directional terms should not be construed as limiting terms.

The implementations described in the following exemplary examples are not representative of all implementations consistent with the present disclosure. Rather, they are merely examples of implementations consistent with aspects of the present disclosure.

The terminology used in the present disclosure is for the purpose of describing particular embodiments only and is not intended to be limiting of the disclosure. As used in this disclosure, the singular forms "a," "an," and "the" are intended to include the plural forms as well, unless the context clearly indicates otherwise. It should also be understood that the term "and/or" as used herein refers to and encompasses any or all possible combinations of one or more of the associated listed items.

The present utility model will be described in further detail with reference to the accompanying drawings.

Referring to fig. 1 and 2, the utility model discloses a harvesting device for chick embryo allantoic fluid, which comprises a suction tube 1, a silica gel sleeve 2 and a liquid suction mechanism (not shown in the drawings); wherein, the suction pipe 1 is a transparent glass pipe, the silica gel sleeve 2 is sleeved at one end of the suction pipe 1, and the suction pipe 1 sucks liquid through the silica gel sleeve 2; the liquid suction mechanism is a suction machine (vacuum suction machine) or a peristaltic pump, and of course, the liquid suction mechanism can also be other mechanisms capable of sucking liquid, the liquid suction mechanism is connected with one end of the suction pipe 1 far away from the silica gel sleeve 2, and the liquid suction mechanism provides suction force for the suction pipe 1 so that the suction pipe 1 can suck allantoic liquid through the silica gel sleeve 2.

When the device is used, the silica gel sleeve 2 is placed in allantoic fluid of chick embryos, and the liquid suction mechanism is utilized to drive the silica gel sleeve 2 to suck the allantoic fluid through the suction pipe 1 so as to obtain the allantoic fluid; the liquid sucking mechanism is a suction machine or a peristaltic pump, and compared with the prior art, the efficiency of obtaining allantoic liquid is improved. The suction tube 1 is a transparent glass tube, the glass tube can be sterilized by dry heat before use, the silica gel sleeve 2 can also be sterilized by wet heat, and the whole harvesting device can be sterilized by sterilizing the liquid suction mechanism, so that the pollution of allantoic fluid during the harvesting of the allantoic fluid is reduced. Because the suction tube 1 is a transparent glass tube, when the allantoic fluid is harvested, the situation of the harvested fluid can be directly seen from the glass tube, such as the occurrence of chick embryo necrosis, egg yolk inhalation and the like, and subsequent measures can be timely found and taken to improve the quality of the harvested allantoic fluid.

In some embodiments, a protrusion 21 for extruding the chick embryo yolk sac body 5 is arranged on one side of the silica gel sleeve 2, the cross section of the protrusion 21 is in arc shape, and the protrusion 21 is positioned in the middle of the silica gel sleeve 2; in use, the yolk sac 5 is pressed by the protrusions 21 to increase the amount of allantoic fluid harvested; the bulge 21 is a semitransparent bulge 21, and the bulge 21 is made of semitransparent silica gel material. The silica gel cover 2 is equipped with the cellular imbibition hole 22 that is used for imbibition, and imbibition hole 22 is located the end of silica gel cover 2, and as shown in fig. 1 and 2, imbibition hole 22 is located the bottom of silica gel cover 2, and in collecting process, the difficult chicken embryo inner structure that punctures of silica gel cover 2. The liquid suction hole 22 comprises a honeycomb hole 221 arranged at the end part of the silica gel sleeve 2 and a suction hole 222 arranged on the peripheral wall of the silica gel sleeve 2, so that the range of sucking allantoic fluid is enlarged from one suction point to a plurality of suction points to form a three-dimensional suction range, and any part at one end of the silica gel sleeve 2 is contacted with the allantoic fluid, so that the allantoic fluid can be harvested, and the efficiency of sucking the liquid is improved.

The implementation principle of the embodiment is as follows: when the harvesting device is used for harvesting allantoic fluid, as shown in figure 1, egg white 7, chicken embryo 4, yolk sac 5 and allantoic body 6 are arranged in an eggshell 3, wherein the allantoic fluid is positioned in the allantoic body 6; the silica gel sleeve 2 is placed in the allantoic body 6 through the suction pipe 1, and the liquid suction mechanism is utilized to drive the silica gel sleeve 2 to suck allantoic liquid in the allantoic body 6 through the suction pipe 1; when allantoic fluid in the allantoic body 6 is gradually reduced, the allantoic body 5 is extruded by the bulge 21, and the bulge 21 is made of silica gel, so that the silica gel is softer and is not easy to puncture the allantoic body 6, the allantoic body 5 is not easy to puncture, and more allantoic fluid can be harvested on the premise of not damaging the allantoic body 5.

The embodiments of the present utility model are all preferred embodiments of the present utility model, and are not intended to limit the scope of the present utility model in this way, therefore: all equivalent changes in structure, shape and principle of the utility model should be covered in the scope of protection of the utility model.

Claims

1. A harvesting device for chick embryo allantoic fluid, comprising:

a suction pipe (1);

the silica gel sleeve (2), the silica gel sleeve (2) is sleeved at one end of the suction pipe (1), and the suction pipe (1) sucks liquid through the silica gel sleeve (2);

the liquid suction mechanism is connected with one end, far away from the silica gel sleeve (2), of the suction pipe (1);

when the chicken embryo suction device is used, the silica gel sleeve (2) is placed in allantoic fluid of a chicken embryo by the suction pipe (1), and the liquid suction mechanism drives the silica gel sleeve (2) to suck the allantoic fluid through the suction pipe (1).

2. A harvesting device for chick embryo allantoic fluid according to claim 1, wherein: one side of the silica gel sleeve (2) is provided with a bulge (21) for extruding the egg yolk sac of the chick embryo.

3. A harvesting device for chick embryo allantoic fluid according to claim 1, wherein: one end of the silica gel sleeve (2) is provided with a honeycomb-shaped liquid suction hole (22) for sucking liquid.

4. A harvesting device for chick embryo allantoic fluid as defined in claim 3, wherein: the liquid suction hole (22) comprises a honeycomb hole (221) arranged at the end part of the silica gel sleeve (2) and a suction hole (222) arranged on the peripheral wall of the silica gel sleeve (2).

5. A harvesting device for chick embryo allantoic fluid according to claim 1, wherein: the suction pipe (1) is a transparent glass pipe.

6. A harvesting device for chick embryo allantoic fluid according to claim 2, wherein: the protrusions (21) are translucent protrusions (21).

7. A harvesting device for chick embryo allantoic fluid according to any of claims 1-5, wherein: the liquid suction mechanism is a suction machine or a peristaltic pump.