CN219385120U - Nucleic acid extractor heating device with right angle protection architecture - Google Patents
Nucleic acid extractor heating device with right angle protection architecture Download PDFInfo
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- CN219385120U CN219385120U CN202223340704.2U CN202223340704U CN219385120U CN 219385120 U CN219385120 U CN 219385120U CN 202223340704 U CN202223340704 U CN 202223340704U CN 219385120 U CN219385120 U CN 219385120U
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- 238000010438 heat treatment Methods 0.000 title claims abstract description 190
- 150000007523 nucleic acids Chemical class 0.000 title claims abstract description 53
- 102000039446 nucleic acids Human genes 0.000 title claims abstract description 53
- 108020004707 nucleic acids Proteins 0.000 title claims abstract description 53
- 239000000919 ceramic Substances 0.000 claims abstract description 13
- 239000004519 grease Substances 0.000 claims description 8
- 229920001296 polysiloxane Polymers 0.000 claims description 8
- 239000003365 glass fiber Substances 0.000 claims description 3
- 230000008859 change Effects 0.000 claims description 2
- 238000000605 extraction Methods 0.000 abstract description 17
- 230000009471 action Effects 0.000 abstract description 9
- 230000000694 effects Effects 0.000 abstract description 8
- 238000004140 cleaning Methods 0.000 abstract description 5
- 230000009286 beneficial effect Effects 0.000 abstract description 3
- 238000006748 scratching Methods 0.000 abstract 1
- 230000002393 scratching effect Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 description 8
- 230000017525 heat dissipation Effects 0.000 description 6
- 230000008569 process Effects 0.000 description 6
- 238000009434 installation Methods 0.000 description 5
- 239000011324 bead Substances 0.000 description 4
- 238000009413 insulation Methods 0.000 description 3
- 239000011248 coating agent Substances 0.000 description 2
- 238000000576 coating method Methods 0.000 description 2
- 238000001514 detection method Methods 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
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- 238000005299 abrasion Methods 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
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Abstract
The utility model discloses a heating device of a nucleic acid extraction instrument with a right-angle protection structure, which belongs to the technical field of nucleic acid extraction instruments and comprises an upper cover plate and a base, wherein the upper cover plate is arranged at the top of the base, a heating assembly and a temperature control assembly are arranged between the base and the upper cover plate, the heating assembly comprises heating clamping grooves and heating plates which are arranged in a matching manner, and two outward protruding clear angles are respectively arranged on one side, away from a wiring port of each heating clamping groove. The beneficial effects of the utility model are as follows: the heating clamping grooves of the bases of the heating devices of the nucleic acid extraction instrument are placed with the heating plates, under the combined action of the heating plates, heating of the nucleic acid extracting solution is achieved, meanwhile, the original right-angle structure is replaced by the corner cleaning structure at the inner corners of the heating clamping grooves, the ceramic heating plates can be conveniently and easily placed in the mounting plates, the protection effect on the corners of the ceramic heating plates is achieved, and scratching, damage and unnecessary cost loss are avoided.
Description
Technical Field
The utility model relates to the technical field of nucleic acid extractors, in particular to a heating device of a nucleic acid extractor with a right-angle protection structure.
Background
The nucleic acid extraction instrument is an instrument for automatically completing sample nucleic acid extraction by using matched nucleic acid extraction reagents, and is widely applied to various fields such as disease control centers, clinical disease diagnosis, blood transfusion safety, forensic identification, environmental microorganism detection, food safety detection, animal husbandry, molecular biology research and the like. The nucleic acid extractor using magnetic bead method uses magnetic bead as carrier, uses the principle that magnetic bead adsorbs nucleic acid under high salt and low pH value, separates nucleic acid under low salt and high pH value, and then uses moving magnetic bead or transferring liquid to implement whole extracting and purifying process of nucleic acid, and its operation is simple and quick, greatly raising experimental efficiency, and its cost is low.
In the process of using a nucleic acid extractor, an extracting solution is required to be heated, in the prior art, a heating device of the nucleic acid extractor lacks a high-efficiency heating structure, corners of the heating plate are easily scratched and damaged by an installing groove during installation of the heating plate, the smooth installation of the heating plate is affected, and meanwhile, a great deal of cost loss is caused, for example, the utility model patent with the publication number of CN216639442U discloses a heating device of the nucleic acid extractor, which comprises a base, a platform is arranged on the base, a heating component is arranged between the platform and the base, the limitation of the heating component in the vertical direction relative to the movement process of a deep hole plate is ensured, the limitation of the heating component in the vertical direction is avoided, and the heating device lacks a protection structure for the heating component, and is inconvenient to disassemble and assemble and control temperature.
Disclosure of Invention
In order to solve the problems that students or vehicles behind are easy to collide with intelligent express trains for backing vehicles and further safety accidents are caused when the unmanned vehicles are backing in the prior art, the utility model provides a nucleic acid extractor heating device with a right-angle protection structure, which comprises an upper cover plate and a base, wherein the upper cover plate is arranged at the top of the base, a heating assembly and a temperature control assembly are arranged between the base and the upper cover plate, the heating assembly comprises a plurality of heating clamping grooves and a plurality of heating plates which are arranged in a matching manner, the heating plates are arranged in the heating clamping grooves in a one-to-one correspondence manner, two outwards protruding clear angles are respectively formed in one side, away from a wiring port of each heating clamping groove, the two clear angles are respectively arranged opposite to two corners of the heating plates, the heating clamping grooves are symmetrically and uniformly distributed at the top of the base, each heating clamping groove is parallel to the length direction of the base, and threading ports of the heating clamping grooves are respectively arranged at two ends of the base.
The heating clamping groove of the base of the nucleic acid extraction instrument heating device is filled with a plurality of heating plates, the upper cover plate of the heating device is connected with the deep hole plate filled with extracting solution, after the heating device is started by the temperature control assembly, the heating of the nucleic acid extracting solution is realized under the combined action of the plurality of heating plates, meanwhile, the inner angle of the heating clamping groove is replaced by the corner cleaning structure to replace the original right-angle structure, the ceramic heating plates can be conveniently and easily placed in the mounting plate, the protection effect on the corners of the heating plates is achieved, scratch and damage and unnecessary cost loss are avoided, and the heating device can be conveniently and stably operated.
Preferably, the temperature control assembly comprises a plurality of temperature control switches and a plurality of temperature control clamping grooves, the plurality of temperature control switches are respectively arranged in the plurality of temperature control clamping grooves, and the plurality of temperature control clamping grooves are respectively arranged at the bottom of the upper cover plate.
The heating temperature of the heating plate is precisely controlled through the temperature control switch and the temperature sensor, so that the nucleic acid extracting solution is conveniently heated by the heating device according to the actual temperature requirement, the influence of overhigh or overlow temperature on the nucleic acid extracting process is avoided, and the accuracy of nucleic acid extraction is ensured.
Preferably, a temperature sensor is installed between any two adjacent temperature control clamping grooves on the upper cover plate.
Preferably, the shape of the clear angle is a three-quarter circle which is prevented from contacting with two right angles at the front end of the heating plate, and the heating plate is a ceramic heating plate.
Preferably, the heat conduction silicone grease is coated in the heating clamping groove and the temperature control clamping groove.
When the heating device is assembled, heat conduction silicone grease is required to be smeared in the heating plate, the temperature control switch and the clamping grooves of the heating plate and the temperature control switch, so that heat conduction and heat dissipation can be facilitated, and the stability of the electrical performance of the heating element is ensured.
Preferably, the upper cover plate is in threaded connection with the base through a plurality of inner mounting holes, a fixing frame is mounted on the outer edge of the joint of the upper cover plate and the base, and the fixing frame is mounted on the top of the base through a plurality of limiting strips.
The upper cover plate is tightly attached to the base, so that the heating plate can fully conduct heat to the upper cover plate, the temperature control switch and the temperature sensor can conveniently and accurately monitor the temperature, the joint of the upper cover plate and the base can be sealed under the action of the positioning frame, the heat insulation effect can be achieved, and heat dissipation is avoided.
Preferably, the outer wall of the fixed frame and the outer wall of the base are respectively provided with a plurality of fixing plates which are arranged up and down correspondingly, and the fixing plates are provided with outer mounting holes which are communicated up and down.
Preferably, the fixing frame is made of glass fiber, and the same fixing screws are respectively arranged in the outer mounting holes and the inner mounting holes.
Connect upper cover plate, fixed frame and base through the fixed screw for whole heating device easily installs and dismantles, has brought the convenience for heating device's use.
Preferably, a plurality of connecting protrusions are arranged on the top of the upper cover plate.
The bottom of base has seted up a plurality of locating hole.
The beneficial effects are that:
the technical scheme of the utility model has the following beneficial effects:
(1) The heating clamping groove of the base of the nucleic acid extraction instrument heating device is filled with a plurality of heating plates, the upper cover plate of the heating device is connected with the deep hole plate filled with extracting solution, after the heating device is started, under the combined action of the plurality of heating plates, the heating of the nucleic acid extracting solution is realized, meanwhile, the inner angle of the heating clamping groove is replaced by the corner cleaning structure by the original right-angle structure, the ceramic heating plates can be conveniently and easily placed in the mounting plate, the protection effect on the corners of the ceramic heating plates is achieved, scratch and damage and unnecessary cost loss are avoided, and the heating device can be conveniently and stably operated.
(2) The heating temperature of the heating plate is precisely controlled through the temperature control switch and the temperature sensor, so that the nucleic acid extracting solution is conveniently heated by the heating device according to the actual temperature requirement, the influence of overhigh or overlow temperature on the nucleic acid extracting process is avoided, and the accuracy of nucleic acid extraction is ensured.
(3) The upper cover plate is tightly attached to the base, so that the heating plate can fully conduct heat to the upper cover plate, the temperature control switch and the temperature sensor can conveniently and accurately monitor the temperature, the joint of the upper cover plate and the base can be sealed under the action of the positioning frame, the heat insulation effect can be achieved, and heat dissipation is avoided.
(4) When assembling heating device, need scribble heat conduction silicone grease in heating plate, temperature detect switch and respective draw-in groove to heat conduction and heat dissipation can be convenient for guarantee heating element's electrical property's stability, through screwed connection upper cover plate, fixed frame and base, make whole heating device easily install and dismantle, brought conveniently for heating device's use.
Drawings
In order to more clearly illustrate the technical solutions of the embodiments of the present utility model, the drawings that are needed in the embodiments will be briefly described below, it being understood that the following drawings only illustrate some examples of the present utility model and therefore should not be considered as limiting the scope, and other related drawings may be obtained according to these drawings without inventive effort for a person skilled in the art.
FIG. 1 is a schematic perspective view showing the whole structure of a heating device of a nucleic acid extractor with a right angle protection structure according to the present utility model;
FIG. 2 is a schematic view of an upper cover plate of the heating device of the present utility model;
FIG. 3 is a schematic view of a heating device fixing frame according to the present utility model;
FIG. 4 is a schematic view of a heating device base and a heating plate according to the present utility model;
FIG. 5 is a schematic diagram of the installation of the bottom of the upper cover plate and the temperature control switch of the heating device of the present utility model;
FIG. 6 is a schematic view of the bottom of the base of the heating device of the present utility model.
In the figure: 1. an upper cover plate; 2. a fixed frame; 3. a base; 4. a fixing piece; 5. an outer mounting hole; 6. a connection protrusion; 7. a heating clamping groove; 8. clearing corners; 9. a heating sheet; 10. a temperature control clamping groove; 11. a temperature control switch; 12. a temperature sensor; 13. a limit bar; 14. an inner mounting hole; 15. and positioning holes.
Detailed Description
For the purpose of making the objects, technical solutions and advantages of the embodiments of the present utility model more apparent, the technical solutions of the embodiments of the present utility model will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present utility model, and it is apparent that the described embodiments are some embodiments of the present utility model, but not all embodiments. Thus, the following detailed description of the embodiments of the utility model, as presented in the figures, is not intended to limit the scope of the utility model, as claimed, but is merely representative of selected embodiments of the utility model. All other embodiments, based on the embodiments of the utility model, which are apparent to those of ordinary skill in the art without inventive faculty, are intended to be within the scope of the utility model.
According to the embodiment, the plurality of heating plates are placed into the heating clamping groove of the base of the heating device of the nucleic acid extraction instrument, the upper cover plate of the heating device is connected with the deep hole plate filled with the extracting solution, after the heating device is started, under the combined action of the plurality of heating plates, the heating of the nucleic acid extracting solution is realized, meanwhile, the inner angle of the heating clamping groove is replaced by the corner cleaning structure, the ceramic heating plates can be conveniently and easily placed into the mounting plate, the protection effect on the corners of the ceramic heating plates is achieved, scratch and damage and unnecessary cost loss are avoided, and the heating device can be conveniently and stably operated. The specific implementation mode is as follows:
as shown in fig. 1 to 6, a nucleic acid extractor heating device with right angle protection architecture, including upper cover plate 1 and base 3, upper cover plate 1 installs in the top of base 3, be provided with heating element and control by temperature change subassembly between base 3 and the upper cover plate 1, heating element includes a plurality of heating draw-in groove 7 and a plurality of heating plate 9 that match and set up, a plurality of heating plate 9 one-to-one sets up in the inside of a plurality of heating draw-in groove 7, two outside bellied clear angles 8 have been seted up respectively to one side that keeps away from heating draw-in groove 7 wiring mouth in every heating draw-in groove 7, two clear angles 8 set up with two corners of heating plate 9 respectively relatively, a plurality of heating draw-in groove 7 symmetrical evenly distributed is in the top of base 3, every heating draw-in groove 7 is parallel with base 3 length direction and the threading mouth of every heating draw-in groove 7 sets up respectively on the outer edge at base 3 both ends. The heating clamping groove 7 of the base 3 of the heating device of the nucleic acid extraction instrument is placed with the plurality of heating plates 9, the upper cover plate 1 of the heating device is connected with the deep hole plate filled with the extracting solution, after the heating device is started by the temperature control component, the heating of the nucleic acid extracting solution is realized under the combined action of the plurality of heating plates 9, meanwhile, the original right-angle structure is replaced by the corner cleaning structure of the inner angle of the heating clamping groove 7, the ceramic heating plates 9 can be conveniently and easily placed into the heating clamping groove 7 for installation, the protection effect on the right-angle corners of the ceramic heating plates 9 is achieved, scratch and damage and unnecessary cost loss are avoided, and the heating device is convenient to stably operate.
The temperature control assembly comprises a plurality of temperature control switches 11 and a plurality of temperature control clamping grooves 10, the plurality of temperature control switches 11 are respectively arranged inside the plurality of temperature control clamping grooves 10, the plurality of temperature control clamping grooves 10 are respectively arranged at the bottom of the upper cover plate 1, and each temperature control switch 11 is connected with and controls one heating plate 9, so that the accurate control of the heating assembly is facilitated.
A temperature sensor 12 is arranged between any two adjacent temperature control clamping grooves 10 on the upper cover plate 1. The heating temperature of the heating plate 9 is precisely controlled through the temperature control switch 11 and the temperature sensor 12, so that the nucleic acid extracting solution is conveniently heated by the heating device according to the actual temperature requirement, the influence of overhigh or overlow temperature on the nucleic acid extracting process is avoided, the accuracy of nucleic acid extraction is ensured, and the temperature sensor 12 is an NTC temperature sensor and is a thermistor.
The shape of the clear angle 8 is three-quarters circle for avoiding contact with two right angles at the front end of the heating plate 9, the heating plate 9 is a ceramic heating plate, when the heating plate 9 is installed, one end of the wiring is close to the edge of the base 3 and outwards extends out of the lead through the wiring port, and the other end is close to the middle part of the base 3 and is close to but not contacted with the two clear angles 8 of the heating clamping groove 7, so that abrasion or scratch of the heating plate 9 is avoided.
The heat conduction silicone grease is coated inside the heating clamping groove 7 and the temperature control clamping groove 10, and when the heating device is assembled, the heat conduction silicone grease is required to be coated on the heating clamping groove 7, the temperature control clamping groove 10, the corresponding heating plate 9 and the temperature control switch 11, so that heat conduction and heat dissipation can be facilitated, and the stability of the electrical performance of the heating element is ensured.
The upper cover plate 1 is in threaded connection with the base 3 through a plurality of inner mounting holes 14, the fixed frame 2 is mounted on the outer edge of the joint of the upper cover plate 1 and the base 3, the fixed frame 2 is mounted on the top of the base 3 through a plurality of limiting strips 13, the upper cover plate 1 is tightly attached to the base 3, the heating plate 9 can be fully conducted to the upper cover plate 1, the temperature control switch 11 and the temperature sensor 12 are also convenient to accurately monitor the temperature, the joint of the upper cover plate 1 and the base 3 can be sealed under the action of the positioning frame 2, the heat insulation effect can be achieved, and heat dissipation is avoided.
The outer wall of fixed frame 2 and the outer wall of base 3 are provided with a plurality of stationary blade 4 that correspond from top to bottom and set up respectively, form on the stationary blade 4 with the outer mounting hole 5 that link up from top to bottom, through outer mounting hole, can be convenient for heating device locking fixedly on the carousel of nucleic acid extraction appearance.
The material of fixed frame 2 is glass fiber, therefore has good heat resistance, is provided with the same set screw respectively in outer mounting hole 5 and the interior mounting hole 14, and the set screw is M3 cup head plum blossom screw, through screwed connection upper cover plate 1, fixed frame 2 and base 3 for whole heating device easily installs and dismantles, has brought conveniently for heating device's use.
The top of upper cover plate 1 is provided with a plurality of connection protruding 6, through connection protruding 6, can be convenient for upper cover plate 1 and nucleic acid extraction appearance deep hole board be connected.
A plurality of locating holes 15 are formed in the bottom of the base 3, and the heating device can be conveniently located and installed in the nucleic acid extraction instrument through the locating holes 15.
The installation steps of the heating device are as follows: the method comprises the steps of firstly, loading six ceramic heating plates into six heating clamping grooves of a heating device, then coating heat-conducting silicone grease, putting aside for standby, secondly, loading six temperature control switches and a temperature sensor into an upper cover plate of the heating device, then coating the heat-conducting silicone grease into the six temperature control clamping grooves, then bonding and locking the upper cover plate of the heating device and a base 3 by using 8M 3 cup head plum blossom screws, thirdly, sleeving a fixing frame outside the locked base and upper cover plate, and then integrally locking the whole on a turntable from bottom to top by using 6M 3 cup head plum blossom screws.
Working principle: the heating clamping groove of the base of the nucleic acid extraction instrument heating device is placed with the plurality of heating plates, the upper cover plate of the heating device is connected with the deep hole plate filled with the extracting solution, after the heating device is started by the temperature control assembly, the heating of the nucleic acid extracting solution is realized under the combined action of the plurality of heating plates, and the temperature is accurately controlled by the temperature control switch and the temperature sensor.
The above description is only of the preferred embodiments of the present utility model and is not intended to limit the present utility model, and various modifications and variations may be made to the present utility model by those skilled in the art. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present utility model should be included in the protection scope of the present utility model.
Claims (10)
1. The utility model provides a nucleic acid extractor heating device with right angle protection architecture, its characterized in that, including upper cover plate (1) and base (3), upper cover plate (1) install in the top of base (3), base (3) with be provided with heating element and control by temperature change subassembly between upper cover plate (1), heating element includes heating cassette (7) and a plurality of heating plate (9) that match and set up, a plurality of heating plate (9) one-to-one set up in a plurality of inside heating cassette (7), every keep away from in heating cassette (7) one side of heating cassette (7) wiring mouth has seted up respectively two outside bellied clear angles (8), two clear angles (8) respectively with two corners of heating plate (9) set up relatively, a plurality of heating cassette (7) symmetrical evenly distributed in the top of base (3), every heating cassette (7) with base (3) length direction parallel and every heating cassette (7) wire through holes respectively set up in on base (3) both ends along.
2. The heating device with the right-angle protection structure for the nucleic acid extractor according to claim 1, wherein the temperature control assembly comprises a plurality of temperature control switches (11) and a plurality of temperature control clamping grooves (10), the plurality of temperature control switches (11) are respectively installed inside the plurality of temperature control clamping grooves (10), and the plurality of temperature control clamping grooves (10) are respectively arranged at the bottom of the upper cover plate (1).
3. The heating device with the right-angle protection structure for the nucleic acid extractor according to claim 2, wherein a temperature sensor (12) is installed between any two adjacent temperature control clamping grooves (10) on the upper cover plate (1).
4. The heating device of the nucleic acid extractor with the right angle protection structure according to claim 1, wherein the clear angle (8) is shaped to avoid three-quarters of a circle contacting two right angles at the front end of the heating plate (9), and the heating plate (9) is a ceramic heating plate.
5. The heating device with the right-angle protection structure for the nucleic acid extractor according to claim 2, wherein the heating clamping groove (7) and the temperature control clamping groove (10) are internally coated with heat-conducting silicone grease.
6. The nucleic acid extractor heating device with the right angle protection structure according to claim 1, wherein the upper cover plate (1) is in threaded connection with the base (3) through a plurality of inner mounting holes (14), a fixing frame (2) is mounted on the outer edge of the joint of the upper cover plate (1) and the base (3), and the fixing frame (2) is mounted on the top of the base (3) through a plurality of limiting strips (13).
7. The heating device with the right-angle protection structure for the nucleic acid extractor, according to claim 6, wherein a plurality of fixing pieces (4) which are arranged vertically and correspondingly are respectively arranged on the outer wall of the fixing frame (2) and the outer wall of the base (3), and outer mounting holes (5) which are communicated with each other vertically are formed in the fixing pieces (4).
8. The heating device for the nucleic acid extractor with the right-angle protection structure according to claim 7, wherein the fixing frame (2) is made of glass fiber, and the same fixing screws are respectively arranged in the outer mounting hole (5) and the inner mounting hole (14).
9. The nucleic acid extractor heating device with right angle protection structure according to claim 1, characterized in that the top of the upper cover plate (1) is provided with a plurality of connecting protrusions (6).
10. The heating device of the nucleic acid extractor with the right angle protection structure according to claim 1, wherein a plurality of positioning holes (15) are formed at the bottom of the base (3).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202223340704.2U CN219385120U (en) | 2022-12-14 | 2022-12-14 | Nucleic acid extractor heating device with right angle protection architecture |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202223340704.2U CN219385120U (en) | 2022-12-14 | 2022-12-14 | Nucleic acid extractor heating device with right angle protection architecture |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN219385120U true CN219385120U (en) | 2023-07-21 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202223340704.2U Active CN219385120U (en) | 2022-12-14 | 2022-12-14 | Nucleic acid extractor heating device with right angle protection architecture |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN219385120U (en) |
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- 2022-12-14 CN CN202223340704.2U patent/CN219385120U/en active Active
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Effective date of registration: 20231222 Address after: Unit 1, Building A1, A5, B1 West, No. 188 Shengxiang East Road, Qiandeng Town, Kunshan City, Suzhou City, Jiangsu Province, 215341 Patentee after: Meidong Huicheng Life Technology (Kunshan) Co.,Ltd. Address before: Second Floor, No. 10, Shihua Avenue West, Daya Bay West District, Huizhou, Guangdong Province, 516000 Patentee before: Meidong Huicheng Life Sciences (Guangdong) Co.,Ltd. |