CN219279874U - Throat swab nucleic acid pathogen separator - Google Patents

Throat swab nucleic acid pathogen separator Download PDF

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Publication number
CN219279874U
CN219279874U CN202223248709.2U CN202223248709U CN219279874U CN 219279874 U CN219279874 U CN 219279874U CN 202223248709 U CN202223248709 U CN 202223248709U CN 219279874 U CN219279874 U CN 219279874U
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tube
inner tube
nucleic acid
cone
cone hopper
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CN202223248709.2U
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Inventor
庞新丰
乔静
李贝
王静
郭步庆
孟伟玲
张林霞
徐伟伟
原艺睿
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Jiaozuo Maternal And Child Health Hospital
Henan University of Technology
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Jiaozuo Maternal And Child Health Hospital
Henan University of Technology
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    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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Abstract

The utility model discloses a nucleic acid pathogen separating device for a throat swab, which comprises an outer tube, an inner tube, a first tube cover and a second tube cover, wherein the outer tube is communicated with the inner tube, a jack is formed in the center of the second tube cover so that the throat swab head can be conveniently inserted into the inner tube, a first cone hopper with a downward tip part is arranged in the inner tube, an annular scraping plate is fixedly connected to the lower end of the first cone hopper, a second cone hopper with an upward tip part is arranged in the inner tube and above the first cone hopper, and a guide tube is fixedly connected to the upper end of the second cone hopper.

Description

Throat swab nucleic acid pathogen separator
Technical Field
The utility model relates to the technical field of nucleic acid detection, in particular to a nucleic acid pathogen separation device for a throat swab.
Background
At present, the nucleic acid detection generally adopts a mixed detection mode, namely a plurality of throat swab heads (generally 10 or 20 throat swab heads) carrying collected cells are broken and collected in a test tube, and as the number of the throat swab heads is increased, the contact between the plurality of throat swab heads stacked in the test tube and preservation solution can be blocked, so that the cell distribution is uneven, the accuracy of the detection is influenced, and the extraction work in a subsequent laboratory is influenced; in addition, when the swab handle is broken, the tube cover is generally required to be opened, the tube cover is pressed, then the swab handle is broken at the mouth of the test tube, and the process is complicated, so that the efficiency is influenced, and the nucleic acid pathogen separating device for the throat swab is provided.
Disclosure of Invention
The utility model aims to provide a nucleic acid pathogen separating device for throat swabs, which solves the problems in the background art.
In order to achieve the above purpose, the present utility model provides the following technical solutions: the utility model provides a throat swab nucleic acid pathogen separator, includes outer tube, inner tube, first tube cover and second tube cover, and the inside splendid attire of outer tube has the preserving fluid that is used for soaking collection cell, outer tube and inner tube communicate each other, and the lower extreme of inner tube is the opening form, can make the lower extreme and the outer tube of inner tube communicate like this, guarantees that preserving fluid can smoothly flow between inner tube, outer tube, the central point of second tube cover puts and opens the inside that has the jack to be convenient for throat swab head to insert the inner tube, the inside of inner tube is equipped with the first cone of pointed end position decurrent, the lower extreme fixedly connected with of first cone is used for scraping the annular scraper blade in preserving fluid with the collection cell on the throat swab head, and the height position of annular scraper blade is less than the liquid level of preserving fluid at least, the inside of inner tube and the top that is located first cone be equipped with the second cone that pointed end position upwards, the upper end fixed connection of second cone is used for carrying out the pipe that leads to the throat swab that inserts in the inner tube.
Preferably, the inside of jack is equipped with the ring sword that is used for breaking off the swab handle off with fingers and thumb, and the ring sword adopts hard plastic material, and the inner circle of ring sword is sharp sword, and the outer lane of ring sword passes through concave-convex structure joint on the lateral wall of jack, the inside of jack just is located the below fixed mounting of ring sword has the elastic sleeve, and the medical rubber material of elastic sleeve's material.
Preferably, the first cone hopper, the second cone hopper and the side wall of the guide pipe are uniformly provided with a plurality of through holes.
Preferably, the annular scraping plate is made of rubber, the annular scraping plate comprises a plurality of petal-shaped structures which are folded towards the middle, the diameter of the lower end of the annular scraping plate is smaller than that of the throat swab head, the throat swab head can outwards open the petal-shaped structures of the annular scraping plate, the deformation of folding towards the middle through the petal-shaped structures of the annular scraping plate is reset, the petal-shaped structures of the annular scraping plate are enabled to be clung to the side wall of the throat swab head, and therefore cells dipped on the throat swab head are scraped.
Preferably, two clamping rings are arranged on the inner side wall of the inner tube, clamping grooves are formed in the outer side walls of the first cone hopper and the second cone hopper, the two clamping rings are fixedly clamped with the two clamping grooves respectively and used for fixing the first cone hopper and the second cone hopper in the inner tube, and the two clamping rings are used for realizing assembly of production and processing.
Compared with the prior art, the utility model has the beneficial effects that:
1. according to the utility model, the annular scraping plate is used for scraping the side wall of the throat swab head, so that collected cells on the throat swab head are promoted to fall into the preservation solution, and the collected cells are scraped into the preservation solution, so that the collected cells can be fully contacted with the preservation solution, the uniformity of the virus concentration of the solution can be improved, and the risk of false negative phenomenon is reduced compared with the traditional mode that the throat swab heads are piled together;
2. according to the utility model, the throat swab head is collected above the second cone, after the outer tube is separated from the inner tube, the throat swab head is taken out from the outer tube along with the inner tube, and the preservation solution is collected in the outer tube, so that the throat swab head is separated from the preservation solution, and the preservation solution in the outer tube is conveniently extracted by a detector;
3. according to the utility model, after the pharyngeal swab head is inserted into the jack, only the swab handle is required to be broken to one side, at the moment, the swab handle is propped against the blade of the annular blade, and after the swab handle is pressed by force, the blade of the annular blade can rapidly break the swab handle, so that the process is simple, convenient and easy to operate.
Drawings
FIG. 1 is a schematic diagram of the overall structure of the present utility model;
FIG. 2 is a cross-sectional exploded view of the outer tube, inner tube and first tube cap of the present utility model;
FIG. 3 is a cross-sectional view of the overall structure of the present utility model;
FIG. 4 is a cross-sectional view of the second tube cap, ring blade and elastomeric sleeve of the present utility model;
FIG. 5 is a cross-sectional view of the outer tube, inner tube, first cone, annular scraper, second cone and conduit of the present utility model;
FIG. 6 is a cross-sectional exploded view of the present utility model at the inner tube, first cone, second cone and conduit;
FIG. 7 is a cross-sectional exploded view of the inner tube, second tube cap, socket, annular blade and elastomeric sleeve of the present utility model;
fig. 8 is a cross-sectional exploded view of the present utility model at the outer tube, inner tube, first tube cap, inner collar and outer collar.
In the figure: 1. the pipe comprises an outer pipe, 2, an inner pipe, 201, a clamping ring, 3, a first pipe cover, 301, an inner convex ring, 4, a second pipe cover, 401, an insertion hole, 5, a first cone bucket, 6, an annular scraping plate, 7, a second cone bucket, 8, a guide pipe, 9, a ring blade, 10, an elastic sleeve, 11, a through hole, 12, a clamping groove, 13 and an outer convex ring.
Detailed Description
The following description of the embodiments of the present utility model will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present utility model, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the utility model without making any inventive effort, are intended to be within the scope of the utility model.
Referring to fig. 1-8, the present utility model provides a technical solution: a nucleic acid pathogen separating device for throat swab comprises an outer tube 1, an inner tube 2, a first tube cover 3 and a second tube cover 4, wherein the inner part of the outer tube 1 is filled with preservation liquid for soaking and collecting cells, the outer tube 1 is communicated with the inner tube 2, as shown in figure 8, the inner side wall of the outer tube 1 is provided with internal threads, the outer side wall of the inner tube 2 is provided with external threads, the outer tube 1 and the inner tube 2 can be connected together through the mutual engagement of the internal threads and the external threads, the lower end of the inner tube 2 is in an opening shape, so that the lower end of the inner tube 2 is communicated with the outer tube 1, the preservation liquid can smoothly flow between the inner tube 2 and the outer tube 1, as shown in figure 8, the outer side walls of the upper ends of the outer tube 1 and the inner tube 2 are respectively provided with an outer convex ring 13, the inner side wall of the first tube cover 3 is provided with an inner convex ring 301, the inner convex ring 13 on the outer tube 1 (the inner tube 2) is connected with the outer convex ring 13, so that the first tube cover 3 can be clamped on the outer tube 1 (the inner tube 2) to realize the sealing of the upper port of the outer tube 1 (the inner tube 2) (for example, the inner tube 2 is covered in the collecting stage and the outer tube 1 can be covered when the inner tube 2 is separated after the laboratory is reached), the center position of the second tube cover 4 is provided with a jack 401 for inserting the throat swab head into the inner tube 2, the inner part of the inner tube 2 is provided with a first cone 5 with a downward tip part, the lower end of the first cone 5 is fixedly connected with an annular scraping plate 6 for scraping the collected cells on the throat swab head into the preserving liquid, the height position of the annular scraping plate 6 is at least lower than the liquid level of the preserving liquid, the inner part of the inner tube 2 is provided with a second cone 7 with an upward tip part above the first cone 5, the upper end of the second cone bucket 7 is fixedly connected with a conduit 8 for guiding the pharyngeal swab inserted into the inner tube 2, and a space for collecting the pharyngeal swab head is reserved between the inner tube 2 and the conduit 8 above the second cone bucket 7;
as shown in fig. 5, during nucleic acid collection, the first tube cover 3 is opened, the collected cells carried by the throat swab head are inserted into the inner tube 2 from the insertion hole 401, the throat swab head inserted into the inner tube 2 is inserted into the guide tube 8, the throat swab head passes through the first cone 5 as the throat swab head is continuously inserted into the guide tube 8, and then the throat swab head is pulled out upwards, the annular scraping plate 6 scrapes the side wall of the throat swab head, so that the collected cells on the throat swab head fall into the preservation solution, and the collected cells are scraped into the preservation solution, so that the throat swab head occupies excessive space, the contact sufficiency between the collected cells and the preservation solution can be improved, and the solution uniformity is improved;
after the pharyngeal swab is drawn out of the catheter 8 (the pharyngeal swab is still positioned inside the inner tube 2 at the moment), the swab handle is broken off to one side at the moment, so that the swab handle can be broken off from the jack 401, the pharyngeal swab can fall into the inner tube 2 (the pharyngeal swab falls on the second cone 7), and collection of the pharyngeal swab is achieved.
As shown in fig. 4 and 7, in order to easily break the swab handle to improve the efficiency of nucleic acid collection, specifically, a ring blade 9 for breaking the swab handle is provided in the interior of the insertion hole 401, the ring blade 9 is made of hard plastic, the inner ring of the ring blade 9 is a sharp blade, the outer ring of the ring blade 9 is clamped on the side wall of the insertion hole 401 through a concave-convex structure, and an elastic sleeve 10 is fixedly installed in the interior of the insertion hole 401 and below the ring blade 9 for bouncing the broken pharyngeal swab head to a central position far away from the inner tube;
as shown in fig. 4 and 7, the lower end of the insertion hole 401 is provided with a ring platform for supporting the elastic sleeve 10, when the ring blade 9 is mounted inside the insertion hole 401, the ring blade 9 presses the elastic sleeve 10 on the ring platform, so that the assembly of the ring blade 9 and the elastic sleeve 10 (which is not mounted during detection in production) is realized, when the swab handle is broken off, the swab handle is broken off to one side, at this time, the swab handle is abutted against the blade of the ring blade 9, the pharyngeal swab head is abutted against the side wall of the elastic sleeve 10 (as shown in fig. 4), after the swab handle is pressed by force, the pharyngeal swab head presses the elastic sleeve 10 to deform, and the blade of the ring blade 9 breaks the swab handle (the existing swab handle is also provided with breaking marks, which are beneficial to the breaking of the swab handle), and after the swab handle is broken off, the pharyngeal swab head can be sprung to a center position far away from the inner tube 2 (namely, a position close to the inner wall of the inner tube 2) through elastic reset of the elastic sleeve 10, so that the swab head is lowered and falls into the catheter 8, and the swab head is concentrated on the second cone 7.
As shown in fig. 3, in order to further ensure smooth circulation of the preservation solution inside the outer tube 1 and the inner tube 2, specifically, the side walls of the first cone 5, the second cone 7 and the conduit 8 are uniformly provided with a plurality of through holes 11;
the broken line shown in fig. 3 is the liquid level of preservation solution, and preservation solution also can soak the throat swab head on the second cone 7 and further improve cell leaching, and when the preservation solution that the inspection personnel need to soak the collection cell after the censoring draws, rotate outer tube 1 and inner tube 2, cause outer tube 1 and inner tube 2 to separate, take out inner tube 2 from outer tube 1 like this, be convenient for the inspection personnel to draw the preservation solution in outer tube 1, and the through-hole 11 that adds can make the inside preservation solution of inner tube 2 can flow to the inside of outer tube 1, avoid preservation solution to hold in the inside of inner tube 2.
As shown in fig. 5, in order to scrape the collected cells on the throat swab head into the preservation solution, specifically, the annular scraping plate 6 is made of rubber, the annular scraping plate 6 comprises a plurality of petal-shaped structures folded toward the middle, the diameter of the lower end of the annular scraping plate 6 is smaller than that of the throat swab head, when the throat swab head penetrates through the first cone 5, the throat swab head can outwards open the petal-shaped structures of the annular scraping plate 6, and the deformation folded toward the middle through the petal-shaped structures of the annular scraping plate 6 is reset, so that the petal-shaped structures of the annular scraping plate 6 are clung to the side wall of the throat swab head to carry out scraping operation.
As shown in fig. 6, in order to rapidly mount the first cone hopper 5 and the second cone hopper 7 in the inner tube 2 for realizing assembly during production and processing, two clamping rings 201 are arranged on the inner side wall of the inner tube 2, clamping grooves 12 are respectively formed in the outer side walls of the first cone hopper 5 and the second cone hopper 7, and the two clamping rings 201 are respectively fixedly clamped with the two clamping grooves 12 for realizing fixing the first cone hopper 5 and the second cone hopper 7 in the inner tube 2.

Claims (5)

1. The utility model provides a throat swab nucleic acid pathogen separator, includes outer tube (1), inner tube (2), first tube cap (3) and second tube cap (4), outer tube (1) and inner tube (2) intercommunication each other, its characterized in that: the utility model discloses a high-pressure pipe, including inner tube (2), second tube cover (4), tip position, annular scraper blade (6) are fixed to the inside of second tube cover (4), the inside of inner tube (2) is equipped with first awl fill (5) of tip position decurrent, the lower extreme fixedly connected with annular scraper blade (6) of first awl fill (5), the inside of inner tube (2) just is located the top of first awl fill (5) and is equipped with second awl fill (7) of tip position decurrent, the upper end fixed connection pipe (8) of second awl fill (7).
2. The nucleic acid pathogen separation device of throat swabs according to claim 1, wherein: the inside of jack (401) is equipped with ring sword (9), the inside of jack (401) and be located ring sword (9) below fixed mounting have elastic sleeve (10).
3. The nucleic acid pathogen separation device of throat swabs according to claim 1, wherein: a plurality of through holes (11) are uniformly formed in the side walls of the first cone hopper (5), the second cone hopper (7) and the guide pipe (8).
4. The nucleic acid pathogen separation device of throat swabs according to claim 1, wherein: the annular scraping plate (6) is made of rubber, and the annular scraping plate (6) comprises a plurality of petal-shaped structures which are folded towards the middle.
5. The nucleic acid pathogen separation device of throat swabs according to claim 1, wherein: two clamping rings (201) are arranged on the inner side wall of the inner tube (2), clamping grooves (12) are formed in the outer side walls of the first cone hopper (5) and the second cone hopper (7), and the two clamping rings (201) are fixedly clamped with the two clamping grooves (12) respectively.
CN202223248709.2U 2022-12-05 2022-12-05 Throat swab nucleic acid pathogen separator Active CN219279874U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202223248709.2U CN219279874U (en) 2022-12-05 2022-12-05 Throat swab nucleic acid pathogen separator

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202223248709.2U CN219279874U (en) 2022-12-05 2022-12-05 Throat swab nucleic acid pathogen separator

Publications (1)

Publication Number Publication Date
CN219279874U true CN219279874U (en) 2023-06-30

Family

ID=86911235

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202223248709.2U Active CN219279874U (en) 2022-12-05 2022-12-05 Throat swab nucleic acid pathogen separator

Country Status (1)

Country Link
CN (1) CN219279874U (en)

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