CN219203735U

CN219203735U - Medical laser for lighting and treatment

Info

Publication number: CN219203735U
Application number: CN202320102717.1U
Authority: CN
Inventors: 韩学坤; 于祥升; 严冬
Original assignee: Qingdao Leishi Optoelectronics Technology Co ltd
Current assignee: Qingdao Leishi Optoelectronics Technology Co ltd
Priority date: 2023-02-02
Filing date: 2023-02-02
Publication date: 2023-06-16
Anticipated expiration: 2033-02-02

Abstract

The application relates to the technical field of laser medical treatment, in particular to a medical laser for illumination and treatment, which comprises: the pump source is used for generating pump light with different wavelengths; the first optical coupling system comprises a plurality of first optical coupling units, and each first optical coupling unit is arranged corresponding to a pumping source with one wavelength; the laser device comprises a first optical coupling unit, a plurality of laser crystals, a second optical coupling unit and a third optical coupling unit, wherein each laser crystal is arranged on a corresponding optical path of the first optical coupling unit, a high reflection film with a preset wave band is plated on the input surface of each laser crystal, a high reflection film with the preset wave band and an antireflection film are plated on the output surface of each laser crystal, and the wave bands of the high reflection film and the antireflection film plated on each laser crystal are different; and a light receiving system for coupling laser light of different wavelengths emitted from the plurality of laser crystals to a single transmission optical fiber.

Description

Medical laser for lighting and treatment

Technical Field

The application relates to the technical field of laser medical treatment, in particular to a medical laser for lighting and treatment.

Background

Laser light is a coherent light source with high brightness, high orientation, and high single color. Camptotipofin is a photosensitizer, and under the irradiation of light with specific wavelength, singlet oxygen can be produced, and the singlet oxygen can make tumor cell toxicity be damaged and die, so that the goal of curing tumor can be reached.

Since laser light has high monochromaticity and constant phase, interference is easy to generate in space, and spots with alternate brightness appear on an imaging surface when the laser light is used for in-vivo illumination, and imaging quality is seriously affected, an LED lamp cap is generally arranged on an optical fiber head. LED light cannot be coupled into a human body through an optical fiber due to a large light volume (light volume=emission width half-width X divergence angle half-angle).

Disclosure of Invention

In order to solve the problem of speckle of laser and the problem of large light parameter area when an LED lamp cap is used for illumination, the application provides a medical laser for illumination and treatment.

A medical laser for use in illumination and treatment, comprising:

the pump source is used for generating pump light with different wavelengths;

the first optical coupling systems are arranged corresponding to the pumping sources with one wavelength;

the laser device comprises a first optical coupling system, a plurality of laser crystals, a second optical coupling system and a third optical coupling system, wherein each laser crystal is arranged on a corresponding optical path of the first optical coupling system, a high reflection film with a preset wave band is plated on the input surface of each laser crystal, a high reflection film with the preset wave band and an antireflection film are plated on the output surface of each laser crystal, and the wave bands of the high reflection film and the antireflection film plated on each laser crystal are different;

and the light receiving system is used for coupling laser light with different wavelengths emitted from the plurality of laser crystals to a single transmission optical fiber.

By adopting the scheme, the technical effect that actually reaches is: the pump source can be used for generating pump light with different wavelengths, the pump light is injected into the corresponding laser crystals through the first optical coupling system, the input surface of each laser crystal is plated with a high reflection film with a preset wave band, the output surface is plated with a high reflection film with the preset wave band and an antireflection film, the wave bands of the high reflection film and the antireflection film plated by each laser crystal are different, so that a light source with a wide spectrum can be obtained, the light source with the wide spectrum is used for illumination before treatment, the phenomenon that single-color laser is easy to interfere in space to generate spots with alternate brightness on an imaging surface is avoided, and the problem that LED light in the prior art cannot enter a human body through optical fiber coupling due to large optical parameter area is overcome.

In one embodiment, the light receiving system includes a second optical coupling system and an optical fiber bundle, the second optical coupling system includes a second optical coupling lens corresponding to the laser crystal one by one, and the optical fiber bundle includes a plurality of optical fibers, each optical fiber corresponds to one of the second optical coupling lenses.

By adopting the technical scheme, the technical effect that reaches is: the optical coupling lens is combined with the optical fiber, so that lasers with different wavelengths generated by the excitation of different laser crystals are coupled into the optical fiber bundle, and the optical coupling lens has the advantages of simple structure and high coupling efficiency.

In one embodiment, the light receiving system includes a light combining structure and a third optical coupling lens, the light combining structure includes a plurality of light combining sheets, the light combining sheets are located on the light path corresponding to each laser crystal to change the transmission direction of the laser beam on the corresponding light path or/and transmit the light with the corresponding wavelength to combine the light with different wavelengths to the third optical coupling lens, and the third optical coupling lens couples the light beam to the transmission optical fiber.

By adopting the technical scheme, the technical effect that reaches is: the light combining piece is combined with a space coupling structure such as an optical coupling lens, laser with different wavelengths generated by the excitation of different laser crystals is combined and focused, and then the laser is coupled into a transmission optical fiber, so that the coupling efficiency is high.

In one embodiment, the multiple pump sources are arranged in parallel, and the light beams generated by each pump source are respectively defined as an nth light beam, wherein N is a natural number, N is greater than or equal to 1, a light combining sheet on the 1 st light beam is used for reflecting the 1 st light beam, and a light combining sheet on the (n+1) th light beam is used for reflecting the nth light beam and transmitting the (n+1) th light beam.

In one embodiment, the pump source is a bar pump source.

In one embodiment, the thickness of the laser crystal is 0.1-20mm, and the doping concentration of the YCOB matrix material doped with Yb3+ rare earth ions is within 50%.

In one embodiment, the laser crystal includes a first crystal, a second crystal and a third crystal, wherein the input end of the first crystal is plated with 1008nm band and 504nm band high reflection films, and the output end is plated with 1008nm band high reflection films and 504nm band antireflection films; the input end of the second crystal is plated with 1076nm wave band and 538nm wave band high reflection films, and the output end is plated with 1076nm wave band high reflection films and 538nm wave band antireflection films; the input end of the third crystal is plated with 1144nm wave band and 572nm wave band high reflection film, and the output end is plated with 1144nm wave band high reflection film and 572nm wave band antireflection film.

By adopting the technical scheme, the technical effect that reaches is: the visible light within the range of 500-580nm is generated, and the visible light with the wave band can be used for searching focus and treating nevus or tumor.

In one embodiment, the first optical coupling system includes a slow axis collimating lens and a fast axis focusing lens sequentially located on an outgoing light path of the pump light, where the slow axis collimating lens close to the pump source is vertically disposed, and the fast axis focusing lens far away from the slow axis collimating lens is laterally disposed.

By adopting the technical scheme, the technical effect that reaches is: the divergence angles of the pump light in the transverse direction and the longitudinal direction are adjusted, and the pump light is collimated and focused, so that as much pump light as possible can enter the laser crystal, and the light utilization rate is improved.

In one embodiment, the slow axis collimating lens and the fast axis focusing lens are cylindrical mirrors, respectively.

In summary, the present application includes at least one of the following beneficial technical effects:

1. the medical laser for the illumination and treatment of the integration comprises a pumping source capable of generating pumping light with different wavelengths, the pumping light is injected into corresponding laser crystals through a first optical coupling system, the input surface of each laser crystal is plated with a high reflection film with a preset wave band, the output surface is plated with a high reflection film with the preset wave band and an antireflection film, the wave bands of the high reflection film and the antireflection film plated by each laser crystal are different, so that a light source with a wide spectrum can be obtained, the light source with the wide spectrum is used for illumination before treatment, and the phenomenon that single-color laser is easy to interfere in space to cause spots with light and dark on an imaging surface is avoided;

2. because the laser with a wide spectrum is used for illumination, the phenomenon that the LED cannot enter the human body through optical fiber coupling due to large light parameter area is overcome, and the phenomenon that the LED emits heat at the focus position during illumination is overcome when the laser is used for illumination.

Drawings

FIG. 1 is a schematic view of a medical laser for illumination and treatment in one body according to a first embodiment of the present application;

fig. 2 is a schematic structural view of the first optical coupling unit used in fig. 1;

FIG. 3 is an emission spectrum of Yb:YCOB crystals;

FIG. 4 is a graph of the front and back surface coating composition of a crystal;

FIG. 5 is a graph of total wavelength output from a crystal after plating graded gradient film layers on the front and back surfaces of the crystal, wherein the center wavelength is at 572nm and the half width is 5nm;

fig. 6 is a schematic structural diagram of a medical laser for illumination and treatment according to a second embodiment of the present application.

Reference numerals illustrate: 1. a pump source; 2. a first optical coupling system; 20. a first optical coupling unit; 3. a laser crystal; 4. a light receiving system; 5. a transmission optical fiber; 40. a second optical coupling system; 42. an optical fiber bundle; 44. an optical fiber; 46. a light combining structure; 48. a third optical coupling lens; 460. a light combining sheet; 31. a first crystal; 32. a second crystal; 33. a third crystal; 201. a slow axis collimating lens; 203. a fast axis focusing lens; 401. and a second optical coupling lens.

Detailed Description

The present application is described in further detail below in conjunction with figures 1-3.

Referring to fig. 1, fig. 1 is a schematic diagram of a medical laser for illumination and treatment according to a first embodiment of the present application, including: the system comprises a pump source 1, a first optical coupling system 2, a plurality of laser crystals 3, an optical receiving system 4 and a transmission optical fiber 5.

The pump source 1 is used for generating pump light of different wavelengths. In the solid laser, mainly semiconductor lasers packaged in various forms such as single tubes, bars, stacked arrays, side pump modules and the like are used as pumping sources 1, and the solid laser works continuously or in pulses and also comprises other types of pumping sources 1 such as xenon lamps, krypton lamps and the like. In this embodiment, a bar is used as the pump source 1.

The first optical coupling system 2 comprises a plurality of first optical coupling units 20, each of said first optical coupling units 20 being arranged in correspondence with a pump source 1 of one wavelength.

In this embodiment, the first optical coupling unit 20 includes a slow axis collimating lens 201 and a fast axis focusing lens 203 sequentially located on the light emitting path of the pump light, and the slow axis collimating lens 201 close to the pump source 1 is vertically disposed, and the fast axis focusing lens 203 far from the slow axis collimating lens 201 is laterally disposed.

Referring to fig. 2, in the present embodiment, the slow axis collimating lens 201 and the fast axis focusing lens 203 are cylindrical mirrors, respectively. Since the bar is formed by serially connecting the laser diodes, the divergence angles of the light beams in the transverse direction and the longitudinal direction are different, and two mutually perpendicular cylindrical mirrors are required to be arranged for adjusting the divergence angles of the light beams.

It will be appreciated that the system of pump source 1 and first optical coupling system 2 becomes a pumping system. The pump light emitted by the pump source 1 is injected into the laser crystal 3 through the coupling component in an end-pumping or side-pumping mode.

Each laser crystal 3 is disposed on a corresponding optical path of the first optical coupling unit 20, and active ions doped in the laser crystal 3 absorb pump light to generate laser transitions, and transitions between different energy levels generate laser light of different wavelengths. The laser crystal 3 can be neodymium-doped laser crystals 3 such as Nd YAG, nd YVO4, nd YLF, nd GdVO4, etc., erbium-doped laser crystals 3 such as Er YAG, er YLF, er YAlO3, etc., holmium-doped laser crystals or thulium-doped laser crystals, etc. In this embodiment, the thickness of the laser crystal 3 is 0.1-20mm, and the doping concentration of the YCOB matrix material doped with yb3+ rare earth ions is within 50%. Yb-YCOB crystals have a broad fluorescence spectrum in the range of 1000-1160nm, corresponding to visible light output in the range of 500-580 nm.

The input surface of each laser crystal 3 is plated with a high reflection film with a preset wave band, the output surface is plated with a high reflection film with a preset wave band and an antireflection film, and the wave bands of the high reflection film and the antireflection film plated by each laser crystal 3 are different.

In this embodiment, the laser crystal 3 includes a first crystal 31, a second crystal 32, and a third crystal 33, where the first crystal 31, the second crystal 32, and the third crystal 33 are frequency doubling crystals, the input end of the first crystal 31 is coated with a 1008nm band high reflection film and a 504nm band high reflection film, and the output end is coated with a 1008nm band high reflection film and a 504nm band antireflection film; the input end of the second crystal 32 is plated with 1076nm wave band and 538nm wave band high reflection films, and the output end is plated with 1076nm wave band high reflection films and 538nm wave band antireflection films; the input end of the third crystal 33 is plated with 1144nm band and 572nm band high reflection films, and the output end is plated with 1144nm band high reflection films and 572nm band antireflection films. The terms "highly reflective", "highly transmissive" and "partially reflective" are used in the art. By "highly reflective" is meant that the reflectance of light at a particular wavelength or wave Duan Rushe is greater than 99%. "high transmission" means a transmission of greater than 80% for a particular wavelength or band of light. "partially transmitted" means that the transmission of light at a particular wavelength or wave Duan Rushe is between 1% and 80%.

It will be appreciated that in other embodiments the number of laser crystals 3 may be more than three.

The light receiving system 4 is used for coupling laser light of different wavelengths emitted from the plurality of laser crystals 3 to a single transmission optical fiber 5. In this embodiment, the light receiving system 4 includes a second optical coupling system 40 and an optical fiber bundle 42, where the second optical coupling system 40 includes a second optical coupling lens 401 corresponding to the laser crystal 3 one by one, and the optical fiber bundle 42 includes a plurality of optical fibers 44, and each optical fiber 44 corresponds to one of the second optical coupling lenses 401.

Referring to FIG. 3, FIG. 3 shows the emission spectrum of Yb/YCOB crystals; yb-YCOB crystals have a broad fluorescence spectrum in the range of 1000-1160nm, corresponding to visible light output in the range of 500-580 nm. When light of a certain wavelength is required to vibrate, light of other wavelengths needs to be suppressed by a film plating mode. The front and back surface coating synthesis curves of the crystal are shown in fig. 4, the abscissa represents wavelength and the ordinate represents transmittance. The transmittance at the solid line wavelength point λ1 is the lowest, the laser is easily oscillated and output, the transmittance at other wavelength points is high, the oscillation is not easily started and suppressed, and the oscillation is easily started at the dashed line wavelength point λ2.λ1 to λ2 are, for example, a band in the range of 500 to 580nm, but are not limited thereto. The specific band range can be set according to actual needs.

The light with each wavelength in the wavelength range from lambda 1 to lambda 2 can be simultaneously output by using one laser, namely, the light with a plurality of wavelengths can be emitted by using the same laser at the same time, so that the wavelength with a wide frequency range can be realized. Specifically, both ends of the crystal can be designed as a gradient system. The film coating layers at different positions of the crystal have small difference, so that the output wavelength corresponding to the lowest transmittance point is inconsistent. When pump laser is coupled to different positions of the crystal, laser oscillation is formed at the corresponding positions of the crystal, and the oscillation wavelength is determined by the film layer at the position, so that the different positions of the crystal can start to oscillate to output light with different wavelengths.

FIG. 5 is a graph of total wavelength output of graded film crystal with a center wavelength at 572nm and a half-width of 5nm. The broad spectrum laser output results in a significant reduction in the coherence of the laser light, thereby effectively suppressing the formation of speckle. In this embodiment, the laser beam may be coupled into an optical fiber having a core diameter of 200 μm; and then coupled into a 400 μm optical fiber by way of three-in-one. The working principle of the medical laser for integrating illumination and treatment is as follows: the pump light emitted by the pump source 1 formed by the bars is focused on the first crystal 31, the second crystal 32 and the third crystal 33 respectively through the first optical coupling system 2; the light of the three wavelengths output by the first crystal 31, the second crystal 32 and the third crystal 33 is coupled into each corresponding optical fiber 44 included in the optical fiber bundle 42, and then coupled into a single one of the transmission optical fibers 5 by three-in-one.

In the prior art, camptothecine is combined with laser to treat tumors, camptothecine is a photosensitizer, and singlet oxygen can be generated under the irradiation of light with specific wavelength, so that tumor cells can be damaged and die due to the singlet oxygen, and the purpose of treating tumors is achieved. From the absorption spectrum of camptothecine, the laser wavelength selection 405nm, 504nm, 538nm, 572nm and 624nm can be easily obtained through semiconductor materials, so the medical laser for illumination and treatment integrated with the application can generate solid laser with three wavelengths of 504, 538 and 572nm by plating a high reflection film and an antireflection film with preset wave bands on the front surface and the rear surface of the laser crystal 3, and the purposes of treating tumors can be achieved by the wavelengths.

The front and rear surfaces of the laser crystal 3 doped with Yb3+ ions form a laser cavity, visible light is output through self frequency doubling effect, finally all the visible light is respectively coupled to the transmission optical fiber 5, the visible light output by the transmission optical fiber 5 can be connected to a medical equipment plug, and the visible light can be used as a medical illumination imaging light source or a camptothecine photodynamic therapy light source.

Referring to fig. 6, fig. 6 is a medical laser for illumination and treatment according to a second embodiment of the present application, and the medical laser for illumination and treatment according to fig. 6 is substantially the same as the first embodiment, in which in this embodiment, the light receiving system 4 includes a light combining structure 46 and a third optical coupling lens 48, the light combining structure 46 includes a plurality of light combining sheets 460, and the light combining sheets 460 are located on the light paths corresponding to each laser crystal 3 to change the transmission direction of the laser beam on the corresponding light path or/and transmit the light with the corresponding wavelength to the third optical coupling lens 48, and the third optical coupling lens 48 couples the light beam to the transmission optical fiber 5.

In one embodiment, the pump sources 1 are arranged in parallel, and the light beams generated by each pump source 1 are respectively defined as an nth light beam, wherein N is a natural number, N is greater than or equal to 1, the light combining sheet 460 on the 1 st light beam is used for reflecting the 1 st light beam, and the light combining sheet 460 on the n+1st light beam is used for reflecting the nth light beam and transmitting the n+1st light beam. The light combining sheet 460 on the n+1th path light beam may use a dichroic mirror.

The working principle of the medical laser for integrating illumination and treatment is as follows: the pump light emitted by the pump source 1 formed by the bars is focused on the first crystal 31, the second crystal 32 and the third crystal 33 through the first optical coupling system 2; the light of three wavelengths output from the first crystal 31, the second crystal 32 and the third crystal 33 is combined into one beam by the light combining structure 46 formed by spatial spectrum, and then coupled into the transmission optical fiber 5 through the third optical coupling lens 48.

In summary, the medical laser for illumination and treatment provided by the application outputs broad spectrum laser through a coating process and a pump coupling design, and the coherence of the laser can be greatly reduced by mixing light with different wavelengths, so that the speckle problem is reduced or even eliminated.

The foregoing are all preferred embodiments of the present application, and are not intended to limit the scope of the present application in any way, therefore: all equivalent changes in structure, shape and principle of this application should be covered in the protection scope of this application.

Claims

1. A medical laser for use in illumination and treatment, comprising:

the pump source is used for generating pump light with different wavelengths;

the first optical coupling system comprises a plurality of first optical coupling units, and each first optical coupling unit is arranged corresponding to a pumping source with one wavelength;

the laser device comprises a first optical coupling unit, a plurality of laser crystals, a second optical coupling unit and a third optical coupling unit, wherein each laser crystal is arranged on a corresponding optical path of the first optical coupling unit, a high reflection film with a preset wave band is plated on the input surface of each laser crystal, a high reflection film with the preset wave band and an antireflection film are plated on the output surface of each laser crystal, and the wave bands of the high reflection film and the antireflection film plated on each laser crystal are different; and

and the light receiving system is used for coupling laser light with different wavelengths emitted from a plurality of laser crystals to a single transmission optical fiber.

2. The medical laser for illumination and treatment according to claim 1, wherein the light receiving system comprises a second optical coupling system including a second optical coupling lens in one-to-one correspondence with the laser crystal and an optical fiber bundle including a plurality of optical fibers each corresponding to one of the second optical coupling lenses.

3. The medical laser for illumination and treatment according to claim 1, wherein the light receiving system comprises a light combining structure and a third light coupling lens, the light combining structure comprising a plurality of light combining sheets, the light combining sheets being located on the light path corresponding to each laser crystal to change the transmission direction of the laser beam on the corresponding light path or/and transmit the light of the corresponding wavelength to combine the light of different wavelengths to the third light coupling lens, the third light coupling lens coupling the light beam to the transmission optical fiber.

4. A medical laser for illumination and treatment according to claim 3, wherein a plurality of said pump sources are arranged in parallel, the beam generated by each pump source being defined as the nth beam, where N is a natural number, N being equal to or greater than 1, the combiner on the 1 st beam being used to reflect the 1 st beam, the combiner on the n+1st beam being used to reflect the nth beam and to transmit the n+1st beam.

5. The medical laser for both illumination and treatment according to claim 1, wherein the pump source is a bar pump source.

6. The medical laser for illumination and treatment according to claim 1, characterized in that the thickness of the laser crystal is 0.1-20mm and the doping concentration of YCOB matrix material doped with yb3+ rare earth ions is within 50%.

7. The medical laser for lighting and curing integrated according to claim 6, wherein the laser crystal comprises a first crystal, a second crystal and a third crystal, wherein the input end of the first crystal is coated with 1008nm wave band and 504nm wave band high reflection film, and the output end is coated with 1008nm wave band high reflection film and 504nm wave band antireflection film; the input end of the second crystal is plated with 1076nm wave band and 538nm wave band high reflection films, and the output end is plated with 1076nm wave band high reflection films and 538nm wave band antireflection films; the input end of the third crystal is plated with 1144nm wave band and 572nm wave band high reflection film, and the output end is plated with 1144nm wave band high reflection film and 572nm wave band antireflection film.

8. The medical laser as claimed in any one of claims 1-7, wherein the first optical coupling unit comprises a slow axis collimating lens and a fast axis focusing lens sequentially positioned on an outgoing light path of the pump light, and the slow axis collimating lens near the pump source is vertically disposed, and the fast axis focusing lens far from the slow axis collimating lens is laterally disposed.

9. The medical laser for both illumination and treatment according to claim 8, wherein the slow axis collimating lens and the fast axis focusing lens are cylindrical mirrors.