CN219179022U - Quantitative detection device for pantoprazole sodium finished product - Google Patents
Quantitative detection device for pantoprazole sodium finished product Download PDFInfo
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- CN219179022U CN219179022U CN202222911381.1U CN202222911381U CN219179022U CN 219179022 U CN219179022 U CN 219179022U CN 202222911381 U CN202222911381 U CN 202222911381U CN 219179022 U CN219179022 U CN 219179022U
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Abstract
The utility model discloses a quantitative detection device for pantoprazole sodium finished products, which comprises a test tube oscillator, a frame body, a distilled water constant volume module, a sample preparation module and a sample constant volume module, wherein the sample preparation module comprises an electric lifting sliding table; a pedestal is fixed on the sliding block of the electric lifting sliding table; a guide bearing is embedded in the inner side of the pedestal; the guide bearing is movably provided with an inverted convex rotary cylinder seat; a tape reel is fixed at the upper part of the outer side of the rotary cylinder seat; the belt disc is arranged with a rotating motor fixed on the pedestal through a driving belt; a vibration motor is fixed at the bottom of the pedestal; the test tube on the test tube oscillator is opposite to the liquid dropping tube. The quantitative detection device for pantoprazole sodium finished products is simple in preparation of the test products, and the test products for detecting the indexes are the same finished products, so that the detection precision is improved.
Description
Technical Field
The utility model particularly relates to a quantitative detection device for pantoprazole sodium finished products, and belongs to the technical field of medical finished product quality analysis equipment.
Background
Pantoprazole sodium is suitable for treating acute upper gastrointestinal hemorrhage such as duodenal ulcer, gastric ulcer, acute gastric mucosal lesion, compound gastric ulcer and the like; commonly used are tablets, capsules and injections; the method comprises the steps of carrying out quantitative detection on pantoprazole sodium finished products according to the marking quantity of the medicines when the detection is carried out, preparing a sample solution when the detection is carried out, sending the sample solution into a high-performance liquid chromatograph or an electrochemical detector, and carrying out quantitative detection through a prepared mobile phase and a reference substance.
Disclosure of Invention
In order to solve the problems, the utility model provides a quantitative detection device for pantoprazole sodium finished products, wherein the samples to be detected are simple to prepare, and the samples to be detected for detecting each index are the same finished product, so that the detection precision is improved.
The utility model relates to a quantitative detection device for pantoprazole sodium finished products, which comprises a test tube oscillator and also comprises
The frame body is provided with a plurality of grooves,
the distilled water constant volume module comprises a distilled water storage tank, a miniature liquid extracting pump and a distilled water constant volume tank with an emptying valve, wherein the distilled water storage tank, the miniature liquid extracting pump and the distilled water constant volume tank are arranged on the frame body; the top and the bottom of the distilled water constant volume tank are integrally provided with thin pipe sections; valve bodies are arranged on the two thin pipe sections; the thin pipe section at the top is provided with scales between the valve body and the distilled water constant volume tank; the top of the thin pipe section at the top is connected to a buffer tank; the buffer tank is connected to the output end of the liquid extracting pump through a hose, and the input end of the liquid extracting pump is connected to the liquid discharging end at the bottom of the distilled water storage tank;
calculating distilled water required by detecting dilution times according to the marked amount of the pantoprazole sodium finished product, accurately obtaining quantitative distilled water through a distilled water constant volume module, closing a valve body at the bottom when the distilled water constant volume tank is constant in volume, rotating the valve body above when the distilled water constant volume tank water amount is fast reached, reducing the flow rate of a thin pipe section, rotating the valve body above again when the thin pipe section is reached, adopting a liquid dropping mode, reading a liquid level value through scales, locking the valve body above when the liquid level value is reached, completing quantitative obtaining of distilled water, and closing a liquid lifting pump; the distilled water is provided with a long thin pipe section above the constant volume tank, so that the constant volume can be performed with high precision;
the sample preparation module comprises an electric lifting sliding table; a pedestal is fixed on the sliding block of the electric lifting sliding table; a guide bearing is embedded in the inner side of the pedestal; the guide bearing is movably provided with an inverted convex rotary cylinder seat; a tape reel is fixed at the upper part of the outer side of the rotary cylinder seat; the belt disc is arranged with a rotating motor fixed on the pedestal through a driving belt; a vibration motor is fixed at the bottom of the pedestal;
the sample constant volume module comprises a large cup body which is of an inverted convex structure and is embedded on the rotary cylinder seat; the center of the large cup body is opposite to the thin pipe section; the bottom of the big cup body is connected with a metering tube; the two ends of the metering tube are integrally provided with a liquid dropping tube; a valve body is arranged on the liquid dropping pipe;
when a test product is prepared, firstly, embedding a large cup body into a rotary cylinder seat, clamping the large cup body with the inner side of the rotary cylinder seat, putting a quantitative pantoprazole sodium finished product tablet, capsule or injection into the large cup body according to the marking amount of a finished product, controlling an electric lifting sliding table to ascend, slowly opening a valve body on a lower thin pipe section, injecting quantitative distilled water to the cup body, starting a rotary motor, and driving a rotary cylinder seat to rotate at a low speed by a belt disc on the rotary motor through a transmission belt and vibrating by a vibrating motor to dissolve the pantoprazole sodium finished product;
the dissolved finished product is quantitatively transferred to each test tube with high precision for constant volume, and the transfer process is as follows: designing a metering tube, arranging drip pipes at the top and the bottom of the metering tube, when the metering tube and the drip pipes are fully filled with the closed valve body, realizing high-precision weighing of finished products, reducing errors in the action of the valve body by utilizing the length and the superfine diameter of the drip pipes, and when the metering tube finishes metering, opening the valve body at the bottom, and sending quantitative dissolving liquid in the metering tube into test tubes, wherein the dissolving liquid in each test tube is in the same batch, so that detection index objects are in the same batch;
the test tube on the test tube oscillator is opposite to the liquid dropping tube;
after each test tube obtains quantitative dissolving liquid, re-injecting reagent solution such as copper sulfate solution, distilled water and the like according to respective detection indexes; fully mixing the test samples through a test tube oscillator to prepare test samples required by respective detection indexes; when the preparation of the test sample is finished, the reference substance adopts a prepared solution or is prepared on site, and when the test sample is prepared on site, the on-site configuration can be carried out, for example, when the content of pantoprazole sodium in the finished product is detected, standard pantoprazole sodium can be dissolved to a dilution factor, and as the reference substance, for example, when the content of disodium edetate in the finished product is detected, standard disodium edetate can be dissolved to the dilution factor, and the detection can be carried out as the reference substance.
Further, an isolation cover is fixed on the upper part of the pedestal; the rotary cylinder seat protrudes out of the top of the isolation cover.
Further, the device also comprises a gland, wherein the bottom of the tubule block is embedded out of the gland and is fixed with the gland; the inner diameter of the gland is larger than the outer diameter of the large cup body.
Further, the metering tube is fixed at the bottom of the pedestal through a clamping seat; the large cup body is connected with the liquid dropping pipe through a rotary joint; the valve body is an electric control valve; the electric control valve is connected to the controller; the controller is connected with a terminal liquid outlet key, the rotation quantity of the cup body is released through the rotary joint, and the liquid dropping pipe and the metering pipe are kept fixed; and can realize electric control liquid outlet.
Further, the upper part and the lower part of the electric lifting sliding table are respectively provided with a proximity switch, and the proximity switches are connected to the controller.
Compared with the prior art, the quantitative detection device for the pantoprazole sodium finished product provided by the utility model has the advantages that the quantitative pantoprazole sodium finished product is dissolved and fixed in volume to obtain the dilution multiple required by detection, and then, high-precision quantitative dissolving liquid is sent to each test tube on an oscillator, so that the sample of each test index is identical.
Drawings
Fig. 1 is a schematic overall structure of embodiment 1 of the present utility model.
Fig. 2 is a schematic structural diagram of a constant volume module for a sample in embodiment 1 of the present utility model.
Fig. 3 is a schematic structural diagram of a constant volume module for a sample according to another embodiment of the present utility model.
Detailed Description
Example 1:
the quantitative detection device for pantoprazole sodium finished products shown in fig. 1 and 2 comprises a test tube oscillator A and also comprises
The frame body (1) is provided with a plurality of grooves,
the distilled water constant volume module comprises a distilled water storage tank 2, a miniature liquid extracting pump 3 and a distilled water constant volume tank 4 with a blow-off valve A, which are arranged on a frame body; the top and the bottom of the distilled water constant volume tank 4 are integrally provided with thin pipe sections 5; the valve bodies 6 are arranged on the two thin pipe sections 5; a scale 7 is arranged between the valve body 6 and the distilled water constant volume tank 2 on the thin pipe section 5 at the top; the top of the thin pipe section 5 is connected to a buffer tank 8; the buffer tank 8 is connected to the output end of the liquid extracting pump 3 through a hose 9, and the input end of the liquid extracting pump 3 is connected to the liquid discharging end at the bottom of the distilled water storage tank 2;
calculating distilled water required by detecting dilution times according to the marked amount of the pantoprazole sodium finished product, accurately obtaining quantitative distilled water through a distilled water constant volume module, closing a valve body at the bottom when the distilled water constant volume tank is constant in volume, rotating the valve body above when the distilled water constant volume tank water amount is fast reached, reducing the flow rate of a thin pipe section, rotating the valve body above again when the thin pipe section is reached, adopting a liquid dropping mode, reading a liquid level value through scales, locking the valve body above when the liquid level value is reached, completing quantitative obtaining of distilled water, and closing a liquid lifting pump; the distilled water is provided with a long thin pipe section above the constant volume tank, so that the constant volume can be performed with high precision;
the sample preparation module comprises an electric lifting sliding table 10; a pedestal 11 is fixed on the sliding block of the electric lifting sliding table 10; a guide bearing 12 is embedded inside the pedestal 11; the guide bearing 12 is movably provided with an inverted convex rotary cylinder seat 13; a tape reel 14 is fixed at the upper part of the outer side of the rotary cylinder seat 13; the reel 14 is mounted with a rotary motor 15 fixed on the pedestal through a transmission belt; a vibration motor 16 is fixed at the bottom of the pedestal 11;
the sample constant volume module comprises a large cup body 17 which is of an inverted convex structure and is embedded on the rotary cylinder seat; the center of the large cup body 17 is opposite to the thin pipe section 5; the bottom of the big cup body 17 is connected with a metering tube 18; the two ends of the metering tube 18 are integrally provided with a liquid dropping tube 19; a valve body 20 is arranged on the liquid dropping pipe 19;
when a test product is prepared, firstly, embedding a large cup body into a rotary cylinder seat, clamping the large cup body with the inner side of the rotary cylinder seat, putting a quantitative pantoprazole sodium finished product tablet, capsule or injection into the large cup body according to the marking amount of a finished product, controlling an electric lifting sliding table to ascend, slowly opening a valve body on a lower thin pipe section, injecting quantitative distilled water to the cup body, starting a rotary motor, and driving a rotary cylinder seat to rotate at a low speed by a belt disc on the rotary motor through a transmission belt and vibrating by a vibrating motor to dissolve the pantoprazole sodium finished product;
the dissolved finished product is quantitatively transferred to each test tube with high precision for constant volume, and the transfer process is as follows: designing a metering tube, arranging drip pipes at the top and the bottom of the metering tube, when the metering tube and the drip pipes are fully filled with the closed valve body, realizing high-precision weighing of finished products, reducing errors in the action of the valve body by utilizing the length and the superfine diameter of the drip pipes, and when the metering tube finishes metering, opening the valve body at the bottom, and sending quantitative dissolving liquid in the metering tube into test tubes, wherein the dissolving liquid in each test tube is in the same batch, so that detection index objects are in the same batch;
the test tube on the test tube oscillator A is opposite to the liquid dropping tube 19;
after each test tube obtains quantitative dissolving liquid, re-injecting reagent solution such as copper sulfate solution, distilled water and the like according to respective detection indexes; fully mixing the test samples through a test tube oscillator to prepare test samples required by respective detection indexes; when the preparation of the test sample is finished, the reference substance adopts a prepared solution or is prepared on site, and when the test sample is prepared on site, the on-site configuration can be carried out, for example, when the content of pantoprazole sodium in the finished product is detected, standard pantoprazole sodium can be dissolved to a dilution factor, and as the reference substance, for example, when the content of disodium edetate in the finished product is detected, standard disodium edetate can be dissolved to the dilution factor, and the detection can be carried out as the reference substance.
A shielding cover 21 is fixed on the upper part of the pedestal 11; the rotary cylinder seat 13 protrudes out of the top of the isolation cover 21.
The device also comprises a gland 22, wherein the gland 22 is embedded in the thin pipe section 5 at the bottom and is fixed with the gland 22; the inner diameter of the gland 22 is larger than the outer diameter of the large cup 17.
In yet another embodiment, as shown in fig. 3, the metering tube 18 is fixed to the bottom of the stand 11 by a clamping seat 23; the large cup body 17 is connected with the drip tube 19 through a rotary joint 24; the valve body is an electric control valve; the electric control valve is connected to the controller; the controller is connected with a terminal liquid outlet key, the rotation quantity of the cup body is released through the rotary joint, and the liquid dropping pipe and the metering pipe are kept fixed; and can realize electric control liquid outlet.
Proximity switches are respectively arranged at the upper part and the lower part of the electric lifting sliding table 10, and the proximity switches are connected to a controller.
The above embodiments are merely preferred embodiments of the present utility model, and all changes and modifications that come within the meaning and range of equivalency of the structures, features and principles of the utility model are therefore intended to be embraced therein.
Claims (5)
1. A quantitative determination device for pantoprazole sodium finished product, includes test tube oscillator, its characterized in that: and also comprises
The frame body is provided with a plurality of grooves,
the distilled water constant volume module comprises a distilled water storage tank, a miniature liquid extracting pump and a distilled water constant volume tank with an emptying valve, wherein the distilled water storage tank, the miniature liquid extracting pump and the distilled water constant volume tank are arranged on the frame body; the top and the bottom of the distilled water constant volume tank are integrally provided with thin pipe sections; valve bodies are arranged on the two thin pipe sections; the thin pipe section at the top is provided with scales between the valve body and the distilled water constant volume tank; the top of the thin pipe section at the top is connected to a buffer tank; the buffer tank is connected to the output end of the liquid extracting pump through a hose, and the input end of the liquid extracting pump is connected to the liquid discharging end at the bottom of the distilled water storage tank;
the sample preparation module comprises an electric lifting sliding table; a pedestal is fixed on the sliding block of the electric lifting sliding table; a guide bearing is embedded in the inner side of the pedestal; the guide bearing is movably provided with an inverted convex rotary cylinder seat; a tape reel is fixed at the upper part of the outer side of the rotary cylinder seat; the belt disc is arranged with a rotating motor fixed on the pedestal through a driving belt; a vibration motor is fixed at the bottom of the pedestal;
the sample constant volume module comprises a large cup body which is of an inverted convex structure and is embedded on the rotary cylinder seat; the center of the large cup body is opposite to the thin pipe section; the bottom of the big cup body is connected with a metering tube; the two ends of the metering tube are integrally provided with a liquid dropping tube; a valve body is arranged on the liquid dropping pipe;
the test tube on the test tube oscillator is opposite to the liquid dropping tube.
2. The quantitative detection device for pantoprazole sodium finished products according to claim 1, characterized in that: an isolation cover is fixed on the upper part of the pedestal; the rotary cylinder seat protrudes out of the top of the isolation cover.
3. The quantitative detection device for pantoprazole sodium finished products according to claim 1, characterized in that: the device also comprises a gland, wherein the bottom of the tubule segment is embedded with the gland and is fixed with the gland; the inner diameter of the gland is larger than the outer diameter of the large cup body.
4. The quantitative detection device for pantoprazole sodium finished products according to claim 1, characterized in that: the metering tube is fixed at the bottom of the pedestal through the clamping seat; the large cup body is connected with the liquid dropping pipe through a rotary joint; the valve body is an electric control valve; the electric control valve is connected to the controller; the controller is connected with a terminal liquid outlet key.
5. The quantitative detection device for pantoprazole sodium finished products according to claim 1, characterized in that: and the upper part and the lower part of the electric lifting sliding table are respectively provided with a proximity switch, and the proximity switches are connected to the controller.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202222911381.1U CN219179022U (en) | 2022-11-02 | 2022-11-02 | Quantitative detection device for pantoprazole sodium finished product |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202222911381.1U CN219179022U (en) | 2022-11-02 | 2022-11-02 | Quantitative detection device for pantoprazole sodium finished product |
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| Publication Number | Publication Date |
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| CN219179022U true CN219179022U (en) | 2023-06-13 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202222911381.1U Active CN219179022U (en) | 2022-11-02 | 2022-11-02 | Quantitative detection device for pantoprazole sodium finished product |
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| CN (1) | CN219179022U (en) |
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