CN218981939U

CN218981939U - Instantaneous centrifugal device with magnetic bead adsorption effect

Info

Publication number: CN218981939U
Application number: CN202222876016.1U
Authority: CN
Inventors: 李坤; 乔恩彬; 叶绍云
Original assignee: Genowise Corp
Current assignee: Genowise Corp
Priority date: 2022-10-31
Filing date: 2022-10-31
Publication date: 2023-05-09
Anticipated expiration: 2032-10-31

Abstract

The utility model discloses an instantaneous centrifugal device with a magnetic bead adsorption effect, which comprises: the magnetic attraction bearing module is arranged on the centrifugal control module; the centrifugal control module includes: the centrifugal power mechanism is arranged in the first bearing mechanism; the magnetic bearing module comprises: the second bearing mechanism and the magnetic attraction mechanism are arranged on the second bearing mechanism; the second bearing mechanism is arranged above the centrifugal power mechanism, and one end of the second bearing mechanism is in transmission connection with the centrifugal power mechanism; the second bearing mechanism is provided with a magnetic attraction area, and the magnetic attraction mechanism is arranged corresponding to the magnetic attraction area; the utility model can directly adsorb the magnetic beads in the centrifuge and centrifuge the centrifuge tube, can simultaneously realize the separation and removal steps of all residual washing liquid required in the magnetic bead purification process by adopting only one device, can completely separate the magnetic beads from the liquid, greatly reduces the time required by the magnetic bead purification, and improves the timeliness and the efficiency of nucleic acid purification.

Description

Instantaneous centrifugal device with magnetic bead adsorption effect

Technical Field

The utility model relates to the field of centrifuges, in particular to an instantaneous centrifugal device with a magnetic bead adsorption effect, which is applied to magnetic bead purification treatment.

Background

At present, a magnetic rack used for purifying nucleic acid by using a magnetic bead method only has a magnetic attraction effect; in the magnetic bead purification process, when the washing liquid is removed, washing liquid residues are remained on the centrifugal tube cover and the tube wall, and if the residual washing liquid is not removed, the quality of a target sample is inevitably influenced; in the actual operation process, when residual washing liquid is sucked and abandoned, a centrifuge tube with magnetic beads is placed into a centrifuge for instantaneous centrifugation, residual liquid is gathered at the bottom of the tube, and then the centrifuge tube is placed onto a magnetic rack for adsorbing the magnetic beads, so that the residual liquid can be completely removed;

therefore, in summary, when the magnetic bead purification is performed at present, two steps of centrifuging the centrifuge tube and adsorbing the magnetic beads are needed to sequentially pass through for removing the residual washing liquid in the centrifuge tube, and in the actual operation process, an experimenter is needed to repeatedly centrifuge the centrifuge tube with the magnetic beads, adsorb the magnetic beads and suck residual liquid, the equipment adopted in the steps are different, and the operation steps are also different, so that the operation amount during the magnetic bead purification is definitely increased, a great amount of time is wasted, the nucleic acid purification time is excessively long, and the quality of a target sample is affected if the residual washing liquid is not completely removed.

Disclosure of Invention

The utility model aims at solving the problems in the prior art, and provides an instantaneous centrifugal device with a magnetic bead adsorption effect, so as to solve the problems that in the prior art, two steps of centrifuging a centrifugal tube and adsorbing magnetic beads are needed to be sequentially carried out through different devices for removing residual washing liquid in the centrifugal tube, thereby increasing the operation amount during magnetic bead purification, wasting a large amount of time and leading to overlong nucleic acid purification time.

In order to solve the technical problems, the utility model adopts a technical scheme that: provided is an instantaneous centrifugal device having a magnetic bead adsorption effect, comprising:

the magnetic attraction bearing module is arranged on the centrifugal control module;

the centrifugal control module includes: a first bearing mechanism and a centrifugal power mechanism arranged in the first bearing mechanism;

the magnetic bearing module comprises: the magnetic attraction mechanism is arranged on the second bearing mechanism; the second bearing mechanism is arranged above the centrifugal power mechanism, and one end of the second bearing mechanism is in transmission connection with the centrifugal power mechanism; the second bearing mechanism is provided with a magnetic attraction area, and the magnetic attraction mechanism is arranged corresponding to the magnetic attraction area;

the centrifugal power mechanism is used for controlling the second bearing mechanism to perform centrifugal action; the magnetic attraction area is used for placing a magnetic bead centrifuge tube, and the magnetic attraction mechanism is used for adsorbing magnetic beads in the magnetic bead centrifuge tube.

As an improvement, the first bearing mechanism includes: a first load bearing housing;

the first bearing shell is horizontally arranged, and a power cavity and an energy supply cavity surrounding the power cavity are arranged in the first bearing shell.

As an improvement, the centrifugal power mechanism includes: a centrifugal motor and a center bearing;

the centrifugal motor is vertically upwards arranged in the first bearing shell;

the center bearing is vertically arranged above the first bearing shell and corresponds to the position of the centrifugal motor, and the lower end of the center bearing rotatably penetrates into the power cavity to be in transmission connection with the output end of the centrifugal motor.

As an improvement, the second bearing mechanism includes: a circular turntable and a transmission connecting piece;

the annular rotary table is horizontally arranged at a position close to the upper end of the central bearing, and the center of the annular rotary table is arranged corresponding to the center of the central bearing;

the transmission connecting piece is arranged at the center of the annular rotary table, the outer side of the transmission connecting piece is connected with the inner side of the annular rotary table through a plurality of supporting pieces, and the bottom of the transmission connecting piece is sleeved at the upper end of the center bearing.

As an improved scheme, a plurality of placing grooves are formed in the upper surface of the circular turntable, and the magnetic attraction areas are arranged at the positions of the placing grooves;

and each placing groove is internally and detachably embedded with a centrifuge tube placing rack.

As an improvement, the magnetic attraction mechanism comprises: an annular magnetic attraction piece;

the specification of the annular magnetic attraction piece is matched with that of the annular rotary table, and the annular magnetic attraction piece is parallel to the annular rotary table;

the annular magnetic attraction piece is sleeved on the outer side of the annular rotary table and corresponds to the positions of the plurality of placing grooves, and the annular magnetic attraction piece is arranged close to the upper positions of the placing grooves.

As an improvement, the instantaneous centrifugal device further comprises: a main body housing and a main body housing cover;

the main body shell is arranged on the upper surface of the first bearing shell around the central bearing, and is lower than the upper end of the central bearing;

the specification of the main body shell cover is matched with that of the main body shell, and the main body shell cover is covered above the magnetic bearing module;

the bottom of the main body shell cover is closely arranged corresponding to the top of the main body shell, and one side of the bottom of the main body shell cover is detachably connected with the top of the main body shell through a clamping piece;

the centrifugal motor is characterized in that a first magnetic attraction induction master switch is arranged at the bottom of the main body shell cover, a first magnetic attraction induction sub-switch is arranged at the top of the main body shell and corresponds to the position of the first magnetic attraction induction master switch, and the first magnetic attraction induction master switch is in communication connection with a controller of the centrifugal motor.

As an improvement, the instantaneous centrifugal device further comprises: a rechargeable battery;

the rechargeable battery is arranged in the energy supply cavity of the first bearing shell, and one end of the rechargeable battery penetrates into the power cavity through a first power supply piece to be electrically connected with the centrifugal motor;

and a charging hole which is communicated with the energy supply cavity and connected with the rechargeable battery is formed in the first bearing shell at a position corresponding to the rechargeable battery.

As an improvement, the instantaneous centrifugal device further comprises: a heat dissipation exhaust fan;

gaps are arranged between the power chamber, the energy supply chamber and the bottom of the first bearing shell; a heat dissipation cavity is arranged in the first bearing shell, below the power cavity and corresponding to the centrifugal motor;

the bottom of the first bearing shell is provided with a heat dissipation hole communicated with the heat dissipation cavity;

the heat dissipation exhaust fan is horizontally arranged in the heat dissipation cavity, the specification of the centrifugal motor is matched with that of the power cavity, and the specification of the heat dissipation cavity is smaller than that of the power cavity.

As an improvement, the instantaneous centrifugal device further comprises: a weight member;

the counterweight is embedded in a gap between the power cavity and the bottom of the first bearing shell; and a heat insulation piece is arranged between the power chamber and the energy supply chamber.

The beneficial effects of the utility model are as follows:

according to the instantaneous centrifugal device with the magnetic bead adsorption effect, the magnetic bead adsorption and centrifugal tube centrifugation can be directly carried out in the centrifugal machine through the mutual matching of the centrifugal control module and the magnetic absorption bearing module, the separation and removal steps of all residual washing liquid required in the magnetic bead purification process can be simultaneously realized by only one device, the magnetic beads and the liquid can be completely separated, the time required by the magnetic bead purification is greatly shortened, the time consumption caused by taking down samples from a magnetic rack for centrifugation for many times when the residual washing liquid is removed in the prior art is reduced, and the time consumption caused by placing the centrifuged samples on the magnetic rack for adsorption is greatly improved, so that the timeliness and the efficiency of nucleic acid purification are greatly improved, the defects of the prior art are overcome, and the instantaneous centrifugal device with the magnetic bead adsorption effect has extremely high application value.

Drawings

FIG. 1 is a schematic perspective view of a transient centrifuge with magnetic bead adsorption effect according to an embodiment of the present utility model;

FIG. 2 is a schematic top view of a transient centrifugal device with magnetic bead adsorption effect according to an embodiment of the utility model;

the components in the drawings are marked as follows:

1. a circular ring type turntable; 2. centrifuge tube rack; 3. a center bearing; 4. a support; 401. a drive connection; 5. a main body cover; 6. an annular magnetic attraction piece; 7. a main body housing; 8. a first load bearing housing; 801. a power chamber; 802. an energizing chamber; 9. a rechargeable battery; 10. a centrifugal motor; 11. a heat insulating member; 12. a heat dissipation exhaust fan; 1201. a heat dissipation chamber; 1202. a heat radiation hole; 13. a weight member; 14. a charging hole; 1501. a first magnetic induction master switch; 1502. a first magnetically attractable sensor switch; 16. a clamping piece.

Detailed Description

The preferred embodiments of the present utility model will be described in detail below with reference to the accompanying drawings so that the advantages and features of the present utility model can be more easily understood by those skilled in the art, thereby making clear and defining the scope of the present utility model.

In the description of the present utility model, it should be understood that the terms "center", "longitudinal", "lateral", "length", "width", "thickness", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "clockwise", "counterclockwise", "axial", "radial", "circumferential", etc. indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings are merely for convenience in describing the present utility model and simplifying the description, and do not indicate or imply that the device or element being referred to must have a specific orientation, be configured and operated in a specific orientation, and therefore should not be construed as limiting the present utility model.

Furthermore, the terms "first," "second," and the like, are used for descriptive purposes only and are not to be construed as indicating or implying a relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defining "a first" or "a second" may explicitly or implicitly include at least one such feature. In the description of the present utility model, the meaning of "plurality" means at least two, for example, two, three, etc., unless specifically defined otherwise.

In the present utility model, unless explicitly specified and limited otherwise, the terms "mounted," "connected," "secured," and the like are to be construed broadly, and may be, for example, fixedly connected, detachably connected, or integrally formed; can be mechanically or electrically connected; either directly or indirectly, through intermediaries, or both, may be in communication with each other or in interaction with each other, unless expressly defined otherwise. The specific meaning of the above terms in the present utility model can be understood by those of ordinary skill in the art according to the specific circumstances.

In the present utility model, unless expressly stated or limited otherwise, a first feature "up" or "down" a second feature may be the first and second features in direct contact, or the first and second features in indirect contact via an intervening medium. Moreover, a first feature being "above," "over" and "on" a second feature may be a first feature being directly above or obliquely above the second feature, or simply indicating that the first feature is level higher than the second feature. The first feature being "under", "below" and "beneath" the second feature may be the first feature being directly under or obliquely below the second feature, or simply indicating that the first feature is less level than the second feature.

It will be understood that when an element is referred to as being "fixed" or "disposed" on another element, it can be directly on the other element or intervening elements may also be present. When an element is referred to as being "connected" to another element, it can be directly connected to the other element or intervening elements may also be present. The terms "vertical," "horizontal," "upper," "lower," "left," "right," and the like are used herein for illustrative purposes only and are not meant to be the only embodiment.

Referring to fig. 1 and 2, an embodiment of the present utility model includes:

an instantaneous centrifugation device with magnetic bead adsorption effect, comprising: the magnetic attraction bearing module is arranged on the centrifugal control module; the centrifugal control module includes: a first bearing mechanism and a centrifugal power mechanism arranged in the first bearing mechanism; the magnetic bearing module comprises: the magnetic attraction mechanism is arranged on the second bearing mechanism; the second bearing mechanism is arranged above the centrifugal power mechanism, and one end of the second bearing mechanism is in transmission connection with the centrifugal power mechanism; the second bearing mechanism is provided with a magnetic attraction area, and the magnetic attraction mechanism is arranged corresponding to the magnetic attraction area; the centrifugal power mechanism is used for controlling the second bearing mechanism to perform centrifugal action; the magnetic attraction area is used for placing a magnetic bead centrifuge tube, and the magnetic attraction mechanism is used for adsorbing magnetic beads in the magnetic bead centrifuge tube; in the prior art, the magnetic beads are repeatedly washed to obtain a high-quality DNA sample, but in the washing process, each step is required to thoroughly remove the residual liquid of the previous washing step, so that the sample is required to be subjected to repeated centrifugation and magnetic bead adsorption operation, and a great amount of time is wasted in the process; therefore, when the magnetic bead purification is carried out, the centrifugal control module and the magnetic absorption bearing module arranged on the centrifugal control module are matched, so that the magnetic bead absorption operation can be carried out while the centrifugal treatment is carried out, the repeated centrifugation and absorption of a sample are not required to be taken down, all the centrifugation and magnetic bead absorption operations can be carried out on the magnetic bead purification device, a great amount of time can be saved, and the operation errors and errors generated in the repeated centrifugation and magnetic bead absorption processes are reduced;

as an embodiment of the present utility model, as shown in fig. 1, the first carrying mechanism includes: a first load-bearing housing 8; in this embodiment, the first bearing housing 8 adopts a base, the first bearing housing 8 is horizontally disposed, and a power chamber 801 and an energy supply chamber 802 disposed around the power chamber 801 are disposed in the first bearing housing 8; the power chamber 801 and the energizing chamber 802 are used for placing a power mechanism and an energizing mechanism, respectively;

as an embodiment of the present utility model, as shown in fig. 1, the centrifugal power mechanism includes: a centrifugal motor 10 and a center bearing 3; the centrifugal motor 10 is vertically upwards arranged in the first bearing shell 8, the central bearing 3 is vertically arranged above the first bearing shell 8 and corresponds to the position of the centrifugal motor 10, and the lower end of the central bearing 3 rotatably penetrates into the power cavity 801 to be in transmission connection with the output end of the centrifugal motor 10; in this embodiment, the lower end of the center bearing 3 may be connected to the output shaft of the centrifugal motor 10 in a coaxial or non-coaxial manner, and when the centrifugal motor is used for centrifugation, the coaxial arrangement is preferred, and the center bearing 3 is mainly controlled by the centrifugal motor 10 to perform a rotation motion;

as an embodiment of the present utility model, as shown in fig. 2, the second carrying mechanism includes: a circular turntable 1 and a transmission connecting piece 401; the annular rotary table 1 is horizontally arranged at a position close to the upper end of the central bearing 3, and the center of the annular rotary table 1 is arranged corresponding to the center of the central bearing 3; in this embodiment, the upper surface of the annular turntable 1 may be flush with the upper end of the center bearing 3, or may be higher than the upper end of the center bearing 3; the transmission connecting piece 401 is arranged at the center of the circular turntable 1, the outer side of the transmission connecting piece 401 is connected with the inner side of the circular turntable 1 through a plurality of supporting pieces 4, and the bottom of the transmission connecting piece 401 is sleeved at the upper end of the center bearing 3; as shown in fig. 2, in this embodiment, the number of the supporting members 4 is 3, and the plurality of supporting members 4 are uniformly arranged around the transmission connecting member 401, the transmission connecting member 401 is an annular member, and the supporting members 4 are used for connecting the transmission connecting member 401 with the annular turntable 1, so as to perform stabilizing and supporting effects; the annular turntable 1 rotates and centrifugally acts by taking the central bearing 3 as a rotating shaft under the action of the centrifugal motor 10 through the supporting piece 4 and the transmission connecting piece 401;

as an implementation mode of the utility model, the upper surface of the circular turntable 1 is uniformly provided with a plurality of placing grooves, and the placing grooves are arranged around the center of the circular turntable 1; the magnetic attraction areas are arranged at the plurality of placing grooves; a centrifuge tube placing rack 2 is detachably embedded in each placing groove; the centrifuge tube placing rack 2 is used for placing the magnetic bead centrifuge tubes, and the magnetic bead centrifuge tubes are centrifuge tubes to be centrifuged, wherein the magnetic beads are arranged in the centrifuge tubes when the magnetic beads are purified; in the embodiment, each centrifuge tube placing rack 2 is arranged in each placing groove in a semi-inlaid manner, so that the centrifuge tube placing rack has stability and is convenient to implement centrifugation;

as one embodiment of the present utility model, the magnetic attraction mechanism includes: an annular magnetic attraction member 6;

the specification of the annular magnetic attraction piece 6 is matched with that of the annular rotary table 1, and the annular magnetic attraction piece 6 is parallel to the annular rotary table 1; in the present embodiment, the annular magnetic attraction piece 6 adopts an annular magnetic attraction strip; the annular magnetic attraction piece 6 is sleeved on the outer side of the annular rotary table 1 and corresponds to the positions of the plurality of placing grooves, and the annular magnetic attraction piece 6 is arranged at the upper position close to the placing grooves; as shown in fig. 1, the annular magnetic attraction piece 6 is inlaid on the outer side surface of the annular rotary table 1 and is used for adsorbing magnetic beads in a magnetic bead centrifuge tube in the centrifuge tube placing frame 2 during the operation of the utility model, so that the magnetic beads are separated from washing liquid in the centrifuge tube;

as an embodiment of the present utility model, the instantaneous centrifugal device further includes: a main body casing 7 and a main body casing cover 5; as shown in fig. 1, the main body casing 7 and the main body casing cover 5 are the outer casing of the present utility model, and function to protect the internal mechanical structure; the main body shell 7 is arranged on the upper surface of the first load-bearing shell 8 around the central bearing 3, and the main body shell 7 is arranged below the upper end of the central bearing 3; the diameter and the shape specification of the main body shell cover 5 are matched with those of the main body shell 7, and the main body shell cover 5 is covered above the magnetic bearing module; the bottom of the main body shell cover 5 is closely arranged corresponding to the top of the main body shell 7, and one side of the bottom of the main body shell cover 5 is detachably connected with the top of the main body shell 7 through a clamping piece 16; in this embodiment, the fastener 16 adopts a cover fastener switch, a part of which is disposed at the bottom of the main body casing cover 5, and another part of which is disposed at the top of the main body casing 7, so as to realize detachable connection between the main body casing cover 5 and the main body casing 7;

a first magnetic induction master switch 1501 is arranged at the bottom of the main body shell cover 5, a first magnetic induction sub-switch 1502 is arranged at the top of the main body shell 7 corresponding to the position of the first magnetic induction master switch 1501, and the first magnetic induction master switch 1501 is in communication connection or electric connection with a controller of the centrifugal motor 10; in this embodiment, the first magnetically-induced female switch 1501 and the first magnetically-induced sub-switch 1502 are mainly used to implement calling and starting of the centrifugal motor 10 when the main body cover 5 and the main body housing 7 are opened, as an example of an embodiment, signal logic of the first magnetically-induced female switch 1501 and the first magnetically-induced sub-switch 1502 is preset, when the main body cover 5 is opened, the first magnetically-induced female switch 1501 and the first magnetically-induced sub-switch 1502 are disconnected and non-contacted, and the centrifugal motor 10 located in the power chamber 801 is in a power-off state; the first magnetic attraction sensing female switch 1501 and the first magnetic attraction sensing male switch 1502 are arranged to be in contact when the main body cover 5 is closed with the main body casing 7, generating an enabling signal for the centrifugal motor 10; thereby realizing intelligent centrifugal control;

as an embodiment of the present utility model, the instantaneous centrifugal device further includes: a rechargeable battery 9; the rechargeable battery 9 is installed in the energy supply chamber 802 of the first bearing housing 8, and one end of the rechargeable battery 9 penetrates into the power chamber 801 through a first power supply piece to be electrically connected with the centrifugal motor 10; the first power supply piece can adopt a power supply line; a charging hole 14 which is communicated with the energy supply chamber 802 and is connected with the rechargeable battery 9 is formed in the first bearing shell 8 at a position corresponding to the rechargeable battery 9; in this embodiment, the rechargeable battery 9 mainly supplies power to the centrifugal motor 10, so as to provide power supply for the centrifugal motor 10, and the charging hole 14 can realize that the external device charges the rechargeable battery 9, and in this embodiment, the types of the rechargeable battery 9 and the charging hole 14 are not limited;

as an embodiment of the present utility model, the instantaneous centrifugal device further includes: a heat radiation exhaust fan 12; gaps are arranged between the power chamber 801 and the energy supply chamber 802 and the bottom of the first bearing shell 8; a heat dissipation chamber 1201 is arranged in the first bearing housing 8 and below the power chamber 801 and at a position corresponding to the centrifugal motor 10; a heat dissipation hole 1202 communicated with the heat dissipation chamber 1201 is formed in the bottom of the first bearing shell 8; the heat dissipation exhaust fan 12 is horizontally arranged in the heat dissipation chamber 1201, the specification of the centrifugal motor 10 is matched with the specification of the power chamber 801, and the specification of the heat dissipation chamber 1201 is smaller than the specification of the power chamber 801; in the present embodiment, the heat radiation exhaust fan 12 and the heat radiation hole 1202 are mainly used for radiating heat for the centrifugal motor 10 in operation;

as an embodiment of the present utility model, the instantaneous centrifugal device further includes: a weight member 13; as an embodiment of the present utility model, the weight 13 is embedded in the power chamber 801 and the gap between the energy supply chamber 802 and the bottom of the first bearing housing 8; a heat insulation member 11 is arranged between the power chamber 801 and the energy supply chamber 802; as shown in fig. 1, the counterweight 13 is made of a counterweight metal strip in the present embodiment, the heat insulating member 11 is made of a vertically arranged heat insulating plate, and the heat insulating plate plays a role in insulating heat between the centrifugal motor 10 and the rechargeable battery 9, so as to ensure the operation safety of the device; the counterweight metal strip plays a counterweight role, so that the running stability of the device is improved;

the working principle of the utility model is as follows:

through the signal logic of the first magnetic attraction sensing master switch 1501 and the first magnetic attraction sensing sub switch 1502, an operator opens the main body shell cover 5 when using the device to perform centrifugation and magnetic bead adsorption, and at the moment, the first magnetic attraction sensing master switch 1501 and the first magnetic attraction sensing sub switch 1502 are disconnected and are not contacted, and the centrifugal motor 10 positioned in the power chamber 801 is in a power-off state; at this time, the magnetic bead centrifuge tubes to be treated can be respectively placed in a plurality of centrifuge tube placing frames 2;

then, preparing to perform centrifugal treatment, so that the main body shell cover 5 is closed to be in contact with the main body shell 7, at the moment, the first magnetic attraction sensing master switch 1501 and the first magnetic attraction sensing sub switch 1502 are in contact to generate an enabling signal for the centrifugal motor 10, after the centrifugal motor 10 receives the enabling signal, the centrifugal motor 10 is electrified to operate through the rechargeable battery 9 so as to drive the central bearing 3 to rotate, the central bearing 3 drives the circular turntable 1 to rotate to generate centrifugal force, and further, the centrifugal effect on the magnetic bead centrifugal tubes in the centrifugal tube placing racks 2 in a plurality of placing grooves is realized, and simultaneously, the annular magnetic attraction pieces 6 inlaid on the side surfaces of the circular turntable 1 adsorb the magnetic beads in the magnetic bead centrifugal tubes to complete instantaneous centrifugal action and magnetic bead adsorption action;

therefore, according to the utility model, the semi-embedded centrifuge tube placing frame 2 uniformly distributed on the annular turntable 1 is adopted, so that the liquid in the magnetic bead centrifuge tube can be ensured to be rapidly gathered at the bottom of the magnetic bead centrifuge tube during centrifugation, and the annular magnetic attraction piece 6 embedded on the side surface of the annular turntable 1 can rapidly adsorb the magnetic beads in the magnetic bead centrifuge tube; when the magnetic beads are purified, the annular magnetic attraction piece 6 adsorbs the magnetic beads, so that the magnetic beads are separated from the washing liquid, and then after the washing liquid on the magnetic beads is removed, the washing liquid is subjected to instantaneous centrifugation again, the residual washing liquid adhered to the centrifuge tube is gathered to the bottom of the centrifuge tube, and the residual washing liquid is thoroughly removed by using a liquid-transferring gun, so that the residual washing liquid in the magnetic bead purification process can be effectively and thoroughly removed in a short time, the defects of the prior art are overcome, and the higher magnetic bead purification efficiency is realized.

The foregoing description is only illustrative of the present utility model and is not intended to limit the scope of the utility model, and all equivalent structures made by the description of the utility model and the accompanying drawings, or direct or indirect application in other related technical fields, are included in the scope of the utility model.

Claims

1. An instantaneous centrifugal device having a magnetic bead adsorption effect, comprising: the magnetic attraction bearing module is arranged on the centrifugal control module;

2. The instantaneous centrifugal device with a magnetic bead adsorption effect according to claim 1, wherein:

the first bearing mechanism comprises: a first load-bearing housing (8);

the first bearing shell (8) is horizontally arranged, and a power chamber (801) and an energy supply chamber (802) surrounding the power chamber (801) are arranged in the first bearing shell (8).

3. The instantaneous centrifugal device with the magnetic bead adsorption effect according to claim 2, wherein:

the centrifugal power mechanism includes: a centrifugal motor (10) and a center bearing (3);

the centrifugal motor (10) is vertically upwards arranged in the first bearing shell (8);

the center bearing (3) is vertically arranged above the first bearing shell (8) and corresponds to the position of the centrifugal motor (10), and the lower end of the center bearing (3) rotatably penetrates into the power cavity (801) to be in transmission connection with the output end of the centrifugal motor (10).

4. A transient centrifugal device having a magnetic bead adsorption effect according to claim 3, wherein:

the second bearing mechanism comprises: a circular turntable (1) and a transmission connecting piece (401);

the annular rotary table (1) is horizontally arranged at a position close to the upper end of the central bearing (3), and the center of the annular rotary table (1) is arranged corresponding to the center of the central bearing (3);

the transmission connecting piece (401) is arranged at the center of the annular rotary table (1), the outer side of the transmission connecting piece (401) is connected with the inner side of the annular rotary table (1) through a plurality of supporting pieces (4), and the bottom of the transmission connecting piece (401) is sleeved at the upper end of the center bearing (3).

5. The instantaneous centrifugal device with the magnetic bead adsorption effect according to claim 4, wherein:

a plurality of placing grooves are formed in the upper surface of the annular rotary table (1), and the magnetic attraction areas are arranged at the positions of the placing grooves;

and a centrifuge tube placing rack (2) is detachably embedded in each placing groove.

6. The instantaneous centrifugal device with the magnetic bead adsorption effect according to claim 5, wherein:

the magnetic attraction mechanism comprises: an annular magnetic attraction piece (6);

the specification of the annular magnetic attraction piece (6) is matched with that of the annular rotary table (1), and the annular magnetic attraction piece (6) is parallel to the annular rotary table (1);

the annular magnetic attraction piece (6) is sleeved on the outer side of the annular rotary table (1) and corresponds to the positions of the plurality of placing grooves, and the annular magnetic attraction piece (6) is arranged close to the upper positions of the placing grooves.

7. A transient centrifugal device having a magnetic bead adsorption effect according to claim 3, wherein:

the instantaneous centrifugation device further comprises: a main body housing (7) and a main body housing cover (5);

the main body shell (7) is arranged on the upper surface of the first bearing shell (8) around the central bearing (3), and the main body shell (7) is arranged lower than the upper end of the central bearing (3);

the specification of the main body shell cover (5) is matched with that of the main body shell (7), and the main body shell cover (5) is covered above the magnetic bearing module;

the bottom of the main body shell cover (5) is tightly abutted against and corresponds to the top of the main body shell (7), and one side of the bottom of the main body shell cover (5) is detachably connected with the top of the main body shell (7) through a clamping piece (16);

the centrifugal motor is characterized in that a first magnetic induction master switch (1501) is arranged at the bottom of the main body shell cover (5), a first magnetic induction sub-switch (1502) is arranged at the top of the main body shell (7) corresponding to the position of the first magnetic induction master switch (1501), and the first magnetic induction master switch (1501) is in communication connection with a controller of the centrifugal motor (10).

8. A transient centrifugal device having a magnetic bead adsorption effect according to claim 3, wherein:

the instantaneous centrifugation device further comprises: a rechargeable battery (9);

the rechargeable battery (9) is arranged in the energy supply cavity (802) of the first bearing shell (8), and one end of the rechargeable battery (9) penetrates into the power cavity (801) through a first power supply piece to be electrically connected with the centrifugal motor (10);

and a charging hole (14) which is communicated with the energy supply cavity (802) and connected with the rechargeable battery (9) is formed in the first bearing shell (8) at a position corresponding to the rechargeable battery (9).

9. A transient centrifugal device having a magnetic bead adsorption effect according to claim 3, wherein:

the instantaneous centrifugation device further comprises: a heat radiation exhaust fan (12);

gaps are arranged between the power chamber (801) and the energy supply chamber (802) and the bottom of the first bearing shell (8); a heat dissipation chamber (1201) is arranged in the first bearing shell (8) and below the power chamber (801) and at a position corresponding to the centrifugal motor (10);

a heat dissipation hole (1202) communicated with the heat dissipation cavity (1201) is formed in the bottom of the first bearing shell (8);

the heat dissipation exhaust fan (12) is horizontally arranged in the heat dissipation chamber (1201), the specification of the centrifugal motor (10) is matched with the specification of the power chamber (801), and the specification of the heat dissipation chamber (1201) is smaller than the specification of the power chamber (801).

10. A transient centrifugal device having a magnetic bead adsorption effect according to claim 3, wherein:

the instantaneous centrifugation device further comprises: a weight member (13);

the counterweight (13) is embedded in the gap between the power chamber (801) and the energy supply chamber (802) and the bottom of the first bearing shell (8); a heat insulation piece (11) is arranged between the power chamber (801) and the energy supply chamber (802).