CN218956599U - Sample analyzer - Google Patents

Sample analyzer Download PDF

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Publication number
CN218956599U
CN218956599U CN202222627044.XU CN202222627044U CN218956599U CN 218956599 U CN218956599 U CN 218956599U CN 202222627044 U CN202222627044 U CN 202222627044U CN 218956599 U CN218956599 U CN 218956599U
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liquid
ultrasonic cleaning
cleaning
sample
needle
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CN202222627044.XU
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Chinese (zh)
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汪云
程蛟
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Shenzhen Mindray Bio Medical Electronics Co Ltd
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Shenzhen Mindray Bio Medical Electronics Co Ltd
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Abstract

The utility model provides a sample analyzer, including sample needle device, reagent needle device, agitating unit, survey device, ultrasonic cleaning device and liquid way device, ultrasonic cleaning device includes a plurality of ultrasonic cleaning ponds, ultrasonic cleaning pond is used for holding the washing liquid and carries out ultrasonic cleaning to the target device in the washing liquid of at least partly inserting, target device includes at least one in sample needle, reagent needle and the puddler, liquid way device includes the feed liquor subassembly, the feed liquor subassembly is used for pouring into the washing liquid to a plurality of ultrasonic cleaning ponds, wherein, the feed liquor subassembly includes the feed liquor structure, feed liquor structure and a plurality of ultrasonic cleaning ponds intercommunication, the feed liquor structure includes first fluid conveyor, a first fluid conveyor is used for the container that the intercommunication holds first washing liquid and drives the first washing liquid in the container that holds first washing liquid and divides to annotate a plurality of ultrasonic cleaning ponds, not only wash effectually, moreover, the pipeline structure sets up simply, the cost is saved.

Description

Sample analyzer
Technical Field
The utility model relates to the technical field of medical instruments, in particular to a sample analyzer.
Background
The functional part for filling liquid or stirring liquid, such as a sample needle for filling a sample, a reagent needle for filling a reagent or a stirring rod for mixing the sample and the reagent, is required to be used in the sample analyzer, and is a part for repeated use, and is contacted with different liquid media in the working process, so that in order to eliminate carrying pollution among different media, the functional part needs to be cleaned after each working so as to remove residual substances on the surface of the functional part, thereby avoiding cross contamination and influencing the accuracy of a test result.
The cleaning effect and cost need to be considered for cleaning the functional parts, but the conventional sample analyzer usually adopts a common cleaning tank to clean the functional parts, so that the cleaning effect is poor.
Disclosure of Invention
In view of this, the present utility model proposes a sample analyzer.
A first aspect of the present utility model proposes a sample analyzer comprising:
a sample needle device comprising a sample needle and a driving device thereof for dispensing a sample;
a reagent needle device comprising a reagent needle and a driving device thereof for dispensing a reagent;
the stirring device comprises a stirring rod and a driving device thereof and is used for mixing a reaction liquid, wherein the reaction liquid is prepared from at least the sample and the reagent;
a measuring device for measuring the reaction liquid;
an ultrasonic cleaning apparatus including a plurality of ultrasonic cleaning tanks for holding a cleaning liquid and ultrasonically cleaning a target device at least partially inserted into the cleaning liquid, the target device including at least one of the sample needle, the reagent needle, and the stirring rod;
a liquid path apparatus comprising a liquid supply assembly for injecting a cleaning liquid into the plurality of ultrasonic cleaning tanks, wherein the liquid supply assembly comprises:
The liquid inlet structure is communicated with the ultrasonic cleaning tanks and comprises a first fluid conveying device, and one first fluid conveying device is used for communicating a container containing a first cleaning liquid and driving the first cleaning liquid in the container containing the first cleaning liquid to be distributed to the ultrasonic cleaning tanks.
A second aspect of the present utility model proposes a sample analyzer comprising:
a sample needle device comprising a sample needle and a driving device thereof for dispensing a sample;
a reagent needle device comprising a reagent needle and a driving device thereof for dispensing a reagent;
the stirring device comprises a stirring rod and a driving device thereof and is used for mixing a reaction liquid, wherein the reaction liquid is prepared from at least the sample and the reagent;
a measuring device for measuring the reaction liquid;
an ultrasonic cleaning apparatus including a plurality of ultrasonic cleaning tanks for holding a cleaning liquid and ultrasonically cleaning a target device at least partially inserted into the cleaning liquid, the target device including at least one of the sample needle, the reagent needle, and the stirring rod;
the liquid way device, including flowing back subassembly, flowing back subassembly is used for discharging the waste liquid in a plurality of ultrasonic cleaning ponds, wherein, flowing back subassembly includes:
The liquid outlet pipes are connected with one ultrasonic cleaning tank;
the liquid outlet valves are connected with the same liquid outlet valve and are used for cutting off or conducting the liquid outlet pipes;
and the second fluid conveying device is connected with the waste liquid valve and is used for driving the waste liquid in the ultrasonic cleaning tanks to be discharged.
A third aspect of the present utility model proposes a sample analyzer comprising:
the reaction device comprises a plurality of placement positions, wherein the placement positions are used for placing reaction cups;
a sample needle device comprising a sample needle and a drive device thereof for dispensing a sample to the cuvette;
a reagent needle device comprising a reagent needle and a driving device thereof for dispensing a reagent into the reaction cup;
the stirring device comprises a stirring rod and a driving device thereof and is used for mixing a reaction liquid, wherein the reaction liquid is prepared from at least the sample and the reagent;
a measuring device for measuring the reaction liquid;
a non-ultrasonic cleaning device for cleaning a first target device with a cleaning liquid, the first target device comprising at least one of the cuvette, the sample needle, the reagent needle, and the stirring rod;
An ultrasonic cleaning device for containing a cleaning liquid and ultrasonically cleaning a second target device at least partially inserted into the cleaning liquid, the second target device including at least one of the sample needle, the reagent needle, and the stirring rod;
liquid path device, including the confession liquid subassembly, the confession liquid subassembly is used for to non-ultrasonic cleaning device with ultrasonic cleaning device pours into the washing liquid into, wherein, the confession liquid subassembly includes:
the first liquid supply pipeline is communicated with the ultrasonic cleaning device;
the second liquid supply pipeline is communicated with the non-ultrasonic cleaning device;
the first fluid conveying device is used for communicating a container containing first cleaning fluid and driving the first cleaning fluid in the container containing the first cleaning fluid to be dispensed to the ultrasonic cleaning device and the non-ultrasonic cleaning device.
A fourth aspect of the present utility model proposes a sample analyzer comprising:
the reaction device comprises a plurality of placement positions, wherein the placement positions are used for placing reaction cups;
a sample needle device comprising a sample needle and a drive device thereof for dispensing a sample to the cuvette;
A reagent needle device comprising a reagent needle and a driving device thereof for dispensing a reagent into the reaction cup;
the stirring device comprises a stirring rod and a driving device thereof and is used for mixing a reaction liquid, wherein the reaction liquid is prepared from at least the sample and the reagent;
a measuring device for measuring the reaction liquid;
the liquid suction device is used for sucking the waste liquid in the reaction cup after cleaning;
an ultrasonic cleaning device for containing a cleaning liquid and ultrasonically cleaning a target device at least partially inserted into the cleaning liquid, the target device including at least one of the sample needle, the reagent needle, and the stirring rod;
the liquid way device, including flowing back subassembly, flowing back subassembly is used for discharging the waste liquid of pipetting device with ultrasonic cleaning device, wherein, flowing back subassembly includes:
the first liquid discharge pipeline is connected with the ultrasonic cleaning device;
the second liquid draining pipeline is connected with the liquid absorbing device;
and the second fluid conveying device is used for driving the liquid suction device and the ultrasonic cleaning device to discharge waste liquid.
According to the technical scheme, the sample analyzer provided by the first aspect of the utility model not only can carry out ultrasonic cleaning on a plurality of target devices by adopting a plurality of ultrasonic cleaning tanks, has a good cleaning effect, but also can dispense the first cleaning liquid to the plurality of ultrasonic cleaning tanks through one first fluid conveying device, thereby improving the working efficiency, simplifying the pipeline structure and saving the cost.
Drawings
In order to more clearly illustrate the technical solutions of the embodiments of the present utility model, the drawings required for the description of the embodiments will be briefly described below, and it is obvious that the drawings in the following description are some embodiments of the present utility model, and other drawings may be obtained by those skilled in the art without the inventive effort.
Fig. 1 is a schematic structural diagram of a sample analyzer according to an embodiment of the present utility model.
Fig. 2 is a schematic structural diagram of a liquid path device and an ultrasonic cleaning tank according to an embodiment of the utility model.
Fig. 3 is a schematic structural diagram of a liquid path device and an ultrasonic cleaning tank according to another embodiment of the present utility model.
Fig. 4 is a schematic structural diagram of a liquid path device and an ultrasonic cleaning tank according to another embodiment of the present utility model.
Fig. 5 is a schematic structural view of an ultrasonic cleaning tank according to an embodiment of the present utility model.
Fig. 6 is a schematic structural diagram of a first liquid separation structure according to an embodiment of the present utility model.
Fig. 7 is a schematic structural diagram of a second liquid separation structure according to an embodiment of the present utility model.
Detailed Description
The following description of the embodiments of the present utility model will be made clearly and fully with reference to the accompanying drawings, in which it is evident that the embodiments described are some, but not all embodiments of the utility model. All other embodiments, which can be made by those skilled in the art based on the embodiments of the utility model without making any inventive effort, are intended to be within the scope of the utility model.
It is also to be understood that the terminology used in the description of the utility model herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the utility model. As used in this specification and the appended claims, the singular forms "a," "an," and "the" are intended to include the plural forms as well, unless the context clearly indicates otherwise.
It should be further understood that the term "and/or" as used in the present specification and the appended claims refers to any and all possible combinations of one or more of the associated listed items, and includes such combinations.
As shown in fig. 1 to 3, an embodiment of the present utility model proposes a sample analyzer 100, and the proposed sample analyzer 100 includes a sample needle device 10, a reagent needle device 20, a stirring device 30, a measuring device 40, an ultrasonic cleaning device 50, and a liquid path device 60.
The sample needle device 10 comprises a sample needle and its driving means for dispensing a sample. In some embodiments, the sample needle may be moved in two or three dimensions by a two or three dimensional drive means so that the sample needle may be moved to aspirate a sample and to a cuvette to be loaded for dispensing the sample.
The reagent needle device 20 comprises a reagent needle and its driving means for dispensing a reagent. In some embodiments, the reagent needle may be moved in two or three dimensions by a two or three dimensional drive means so that the reagent needle may be moved to aspirate reagent and to a reaction cup to be loaded for dispensing reagent.
The stirring device 30 includes a stirring rod and a driving device thereof for mixing a reaction solution prepared from at least the sample and the reagent. In some embodiments, the stirring rod can perform two-dimensional or three-dimensional movement through the driving device thereof and drive the stirring rod to perform stirring action, and the reaction liquid is formed after uniform mixing and incubation reaction through the stirring device 30.
To prevent cross-contamination, the sample analyzer 100 may clean sample pins, reagent pins, stirring bars, etc. during the test procedure. In some usage scenarios, an item test needs to go through the following procedure: adding a sample and a reagent, uniformly mixing and incubating a reaction solution formed by the sample and the reagent, and measuring the incubated reaction solution; in this process, the sample needle generally needs to be cleaned after discharging the sample once and before sucking the next sample to prevent cross contamination; similarly, the reagent needle typically needs to be cleaned after discharging the primary reagent and before sucking the next reagent to prevent cross contamination; similarly, the stirring device 30 generally needs to be cleaned after stirring the reaction liquid in one reaction cup by using a stirring rod and before stirring the reaction liquid in the next reaction cup to prevent cross contamination.
The measuring device 40 is used for measuring the reaction solution. In some embodiments, the measurement device 40 may include a light measurement device for performing light measurement on the incubated reaction solution to obtain reaction data of the sample. For example, the light measuring device detects the luminous intensity of the reaction liquid to be measured, and calculates the concentration of the component to be measured in the sample through a calibration curve.
The ultrasonic cleaning apparatus 50 includes a plurality of ultrasonic cleaning tanks 51 for containing a cleaning liquid and ultrasonically cleaning a target device at least partially inserted into the cleaning liquid, the target device including at least one of a sample needle, a reagent needle, and a stirring rod. The ultrasonic cleaning of the embodiment of the utility model utilizes cavitation, acceleration, direct flow and/or other effects of ultrasonic waves in liquid to directly and indirectly act on the liquid and pollutants, so that the pollutants are dispersed, emulsified and peeled off to achieve the cleaning purpose. Generally, ultrasonic cleaning can peel off dirt from the surface of an object to be cleaned by utilizing intense cavitation and vibration generated by ultrasonic waves, and can decompose and emulsify greasy dirt. In some embodiments, since the liquid medium contacted by each target device is different, each ultrasonic cleaning tank 51 is used for cleaning one type of target device correspondingly, for example, the first ultrasonic cleaning tank is used for cleaning only the sample needle, the second ultrasonic cleaning tank is used for cleaning only the reagent needle, and the third ultrasonic cleaning tank is used for cleaning only the stirring rod. Of course, in other embodiments, each ultrasonic cleaning tank 51 may also clean multiple types of target devices.
The liquid path apparatus 60 includes a liquid supply assembly 61, and the liquid supply assembly 61 is used to inject cleaning liquid into the plurality of ultrasonic cleaning tanks 51. The cleaning solution provided by the embodiment of the utility model comprises liquid media such as normal saline, distilled water or diluent, or some media which can be subjected to chemical reaction with pollutants on the target device, for example, some acidic liquids, and the like.
In some embodiments, the sample analyzer 100 further comprises a reaction device 70, the reaction device 70 having at least one placement site for placing a reaction cup and incubating a reaction solution in the reaction cup. For example, the reaction device 70 may be a reaction disk, which is arranged in a disk-shaped structure and has one or more placement sites for placing reaction cups, and the reaction disk can rotate and drive the reaction cups in the placement sites to rotate for dispatching the reaction cups in the reaction disk and incubating the reaction liquid in the reaction cups.
In some embodiments, the sample analyzer 100 further comprises a sample carrier 80, the sample carrier 80 for carrying a sample. As one embodiment, the sample carrier 80 may include a sample distribution module (SDM, sample Delivery Module) and a front end rail. As another example, the sample carrier device 80 may be a sample tray comprising a plurality of sample locations where sample can be placed, such as sample tubes, and the sample tray may be maneuvered to a corresponding position by rotating its tray structure, such as a position for the sample needle device 10 to aspirate the sample.
In some embodiments, the sample analyzer 100 further comprises a reagent carrier 90, the reagent carrier 90 for carrying a reagent. Illustratively, the reagent carrying apparatus 90 may be a reagent disk, which is provided in a disk-like structure having a plurality of positions for carrying reagent containers, and the reagent carrying apparatus 90 is capable of rotating and driving the reagent containers carried thereby to rotate the reagent containers to a specific position, such as a position where reagent is sucked by the reagent needle device 20. The number of reagent carrying apparatus 90 may be one or more.
As shown in fig. 2 and 3, in some embodiments, the liquid supply assembly 61 includes a liquid inlet structure 611, the liquid inlet structure 611 is in communication with the plurality of ultrasonic cleaning tanks 51, the liquid inlet structure 611 includes a first fluid delivery device 6111, and one first fluid delivery device 6111 is configured to communicate with a container containing the first cleaning liquid and drive the first cleaning liquid in the container containing the first cleaning liquid to be dispensed into the plurality of ultrasonic cleaning tanks 51.
In this embodiment, not only a plurality of ultrasonic cleaning tanks 51 are adopted to perform ultrasonic cleaning on a plurality of target devices, and the ultrasonic cleaning tank has the effect of powerful stripping cleaning, can effectively eliminate accumulated pollutant residues on the target devices, has a good cleaning effect, but also can dispense the first cleaning solution to the plurality of ultrasonic cleaning tanks 51 through a first fluid conveying device 6111, improves the working efficiency, has simple pipeline structure, and saves the cost because the plurality of ultrasonic cleaning tanks 51 share one liquid supply assembly 61.
As shown in fig. 2, 3, and 6, in some embodiments, the liquid supply assembly 61 further includes a first liquid dividing structure 612, the first liquid dividing structure 612 including a first liquid inlet 6121 and a plurality of first liquid outlets 6122, the first liquid inlet 6121 being in communication with the liquid inlet structure 611, the plurality of first liquid outlets 6122 being in communication with the plurality of ultrasonic cleaning tanks 51. Illustratively, the first fluid-dividing structure 612 may be a multi-way pipe, for example, when the number of ultrasonic cleaning tanks 51 is two, the first fluid-dividing structure 612 may be a three-way pipe. Illustratively, the first fluid-dividing structure 612 may also be a diverter valve to facilitate simultaneous fluid intake from multiple ultrasonic cleaning tanks 51.
As shown in fig. 2-6, in some embodiments, the fluid supply assembly 61 further includes a plurality of fluid intake pipes 613, the plurality of fluid intake pipes 613 in communication with the plurality of first fluid outlets 6122, each fluid intake pipe 613 extending to one of the ultrasonic cleaning tanks 51. Illustratively, each of the liquid inlet pipes 613 is connected to the liquid inlet 511 of one of the ultrasonic cleaning tanks 51, and a cleaning liquid is simultaneously dispensed into the ultrasonic cleaning tanks 51 through the first liquid dispensing structure 612 and the liquid inlet pipes 613 under the driving of the first fluid conveying device 6111.
As shown in fig. 2 and 3, in some embodiments, the liquid inlet structure 611 further includes a liquid inlet valve 6112, where the liquid inlet valve 6112 is disposed between the first liquid separating structure 612 and the first fluid conveying device 6111, the liquid inlet valve 6112 is used to turn off or turn on the liquid inlet structure 611, and the first fluid conveying device 6111 is used to drive the first cleaning liquid in the container containing the first cleaning liquid to enter the first liquid separating structure 612 through the liquid inlet valve 6112 and be dispensed into the plurality of ultrasonic cleaning tanks 51. In some usage scenarios, when the liquid inlet valve 6112 is turned on, the first fluid conveying device 6111 is communicated with the first liquid separating structure 612, so that the first fluid conveying device 6111 drives the first cleaning liquid to enter the first liquid separating structure 612 through the turned-on liquid inlet valve 6112 and be separated into the plurality of ultrasonic cleaning tanks 51. When the liquid inlet valve 6112 is closed, the first fluid conveying device 6111 is not communicated with the first liquid separating structure 612, so that liquid backflow is avoided.
As shown in fig. 2 and 6, in some embodiments, the number of the liquid inlet structures 611 is at least two, and at least two liquid inlet structures 611 are communicated with the first liquid inlet 6121, each liquid inlet structure 611 is used for conveying cleaning liquid to the plurality of ultrasonic cleaning tanks 51, and the types of the cleaning liquid conveyed by the at least two liquid inlet structures 611 are different. By this arrangement, different types of cleaning liquid can be dispensed into the plurality of ultrasonic cleaning tanks 51 through the same first liquid dispensing structure 612, and cost can be saved. In the cleaning process, different types of cleaning liquid can be used for cleaning the target device in sequence, and one cleaning liquid can also be used for cleaning the target device.
Specifically, each liquid inlet structure 611 includes a first fluid conveying device 6111 and a liquid inlet valve 6112, when one liquid inlet structure 611 injects liquid into the plurality of ultrasonic cleaning tanks 51, the liquid inlet valve 6112 of the liquid inlet structure 611 of the current liquid injection is turned on, and the liquid inlet valves 6112 of the other liquid inlet structures 611 are turned off.
It should be noted that, as shown in fig. 3, in other embodiments, when there is only one cleaning solution, the number of the liquid inlet structures 611 may be one.
As shown in fig. 2 and 7, in some embodiments, the liquid supply assembly 61 further includes a second liquid separating structure 614, the second liquid separating structure 614 includes a second liquid outlet 6141 and at least two second liquid inlets 6142, the second liquid outlet 6141 is communicated with the first liquid inlet 6121, and the at least two second liquid inlets 6142 are correspondingly communicated with the at least two liquid inlets 611, so that each liquid inlet structure 611 can convey cleaning liquid to the plurality of ultrasonic cleaning tanks 51, and the types of the cleaning liquid conveyed by the at least two liquid inlets 611 are different. Illustratively, the second fluid-dividing structure 614 may be a multi-way pipe, for example, when the number of ultrasonic cleaning tanks 51 is two, the second fluid-dividing structure 614 may be a three-way pipe.
As shown in fig. 2, in some embodiments, the liquid supply assembly 61 further includes a liquid supply pipe 615, the liquid supply pipe 615 is connected between the second liquid outlet 6141 and the first liquid inlet 6121, and the cleaning liquid injected into each liquid inlet structure 611 enters the first liquid distribution structure 612 through the second liquid distribution structure 614 and the liquid supply pipe 615, and is distributed to the plurality of ultrasonic cleaning tanks 51 through the plurality of liquid supply pipes 613. At least two liquid inlet structures 611 share a section of pipelines of a first liquid separating structure 612, a second liquid separating structure 614, a liquid conveying pipe 615 and a plurality of liquid inlet pipes 613 so as to realize liquid injection to a plurality of ultrasonic cleaning tanks 51, thereby saving cost. In some usage scenarios, since a manifold section formed by the first liquid separating structure 612 and the plurality of liquid inlet pipes 613 may have uneven resistance, resulting in a problem that some of the ultrasonic cleaning tanks 51 are filled and other of the ultrasonic cleaning tanks 51 are not filled, the first fluid conveying device 6111 needs to perform excessive liquid filling to ensure that the plurality of ultrasonic cleaning tanks 51 are filled with cleaning liquid, and the last cleaning agent remained in the common manifold section is discharged completely through filling.
In some embodiments, the first fluid delivery device 6111 may employ an infusion pump or an air compressor, or a combination of an infusion pump and an air compressor. In some usage scenarios, the cleaning liquid can be pumped into the infusion tube 615 directly through the infusion pump and is distributed to the plurality of ultrasonic cleaning tanks 51 through the first liquid distribution structure 612, the cleaning liquid can be pressed into the infusion tube 615 directly through the air compressor and is distributed to the plurality of ultrasonic cleaning tanks 51 through the first liquid distribution structure 612, the cleaning liquid can be driven into the container through one of the infusion pump and the air compressor, and the cleaning liquid in the container can be driven into the infusion tube 615 through the other one of the infusion pump and the air compressor and is distributed to the plurality of ultrasonic cleaning tanks 51 through the first liquid distribution structure 612.
As shown in fig. 2 and 3, in some embodiments, the sample analyzer 100 further includes a drain assembly 62, where the drain assembly 62 includes a plurality of liquid outlet pipes 621, a liquid outlet valve 622, and a second fluid delivery device 623, each liquid outlet pipe 621 is connected to one ultrasonic cleaning tank 51, the liquid outlet valve 622 is connected to the liquid outlet pipe 621 for blocking or conducting the liquid outlet pipe 621, the second fluid delivery device 623 is connected to the liquid outlet valve 622, and the second fluid delivery device 623 is used for driving the liquid waste in the plurality of ultrasonic cleaning tanks 51 to drain; wherein, at least two drain pipes 621 are connected to the same waste liquid valve 622, the waste liquid valve 622 has a plurality of inlets and an outlet, the plurality of inlets of the waste liquid valve 622 are correspondingly connected to at least two drain pipes 621, the outlet of the waste liquid valve 622 is connected to the second fluid conveying device 623, and the waste liquid valve 622 is used for switching on each inlet in turn so as to discharge the waste liquid in the plurality of ultrasonic cleaning tanks 51 one by one. This arrangement connects at least two liquid outlet pipes 621 to the same liquid outlet valve 622, and the liquid outlet valve 622 may be a multi-channel liquid outlet valve 622, so that the number of liquid outlet valves 622 is less than the number of ultrasonic cleaning tanks 51, and cost is saved.
Illustratively, in the case where the number of ultrasonic cleaning tanks 51 is two, the waste liquid valve 622 employs one three-way valve. Of course, each ultrasonic cleaning tank 51 may be connected to a single-channel waste liquid valve.
In some usage scenarios, when the plurality of ultrasonic cleaning tanks 51 drain, if the cost of draining the liquid by arranging one second fluid conveying device 623 corresponding to one ultrasonic cleaning tank 51 is too high, if the plurality of ultrasonic cleaning tanks 51 drain together with a situation of uncleanness, the waste liquid valve 622 with a plurality of inlets and one outlet is adopted, so that one second fluid conveying device 623 can drain the waste liquid of the plurality of ultrasonic cleaning tanks 51 one by one, and the drainage is ensured to be clean.
In some embodiments, the second fluid delivery device 623 may employ a positive displacement pump or a vacuum pump, or a combination of a positive displacement pump and a vacuum pump. In some use scenarios, the waste liquid of the plurality of ultrasonic cleaning tanks 51 can be directly discharged through the liquid discharge pump, the waste liquid of the plurality of ultrasonic cleaning tanks 51 can be directly pumped out through the vacuum pump, and the waste liquid of the plurality of ultrasonic cleaning tanks 51 can be discharged through the cooperation of the liquid discharge pump and the vacuum pump.
As shown in fig. 1 to 3, the embodiment of the present utility model also proposes a sample analyzer 100, the proposed sample analyzer 100 comprising a sample needle device 10, a reagent needle device 20, a stirring device 30, a measuring device 40, an ultrasonic cleaning device 50, and a liquid path device 60, the sample needle device 10 comprising a sample needle and a driving device thereof for dispensing a sample, the reagent needle device 20 comprising a reagent needle and a driving device thereof for dispensing a reagent, the stirring device 30 comprising a stirring rod and a driving device thereof for mixing a reaction liquid prepared from at least the sample and the reagent, the measuring device 40 for measuring the reaction liquid, the ultrasonic cleaning device 50 comprising a plurality of ultrasonic cleaning tanks 51 for holding a cleaning liquid and performing ultrasonic cleaning on a target device at least partially inserted into the cleaning liquid, the target device comprising at least one of the sample needle, the reagent needle, and the stirring rod, the liquid path device 60 comprising a liquid discharging assembly 62, the liquid discharging assembly 62 for discharging a waste liquid in the plurality of ultrasonic cleaning tanks 51.
The liquid discharging assembly 62 includes a plurality of liquid outlet pipes 621, a plurality of liquid outlet valves 622 and a second fluid conveying device 623, each liquid outlet pipe 621 is connected with one ultrasonic cleaning tank 51, the plurality of liquid outlet pipes 621 are connected with the same liquid outlet valve 622, the liquid outlet valves 622 are used for cutting off or conducting the liquid outlet pipes 621, the second fluid conveying device 623 is connected with the liquid outlet valves 622, and the second fluid conveying device 623 is used for driving the liquid waste in the ultrasonic cleaning tanks 51 to be discharged. This arrangement connects a plurality of drain pipes 621 to the same waste liquid valve 622, so that a second fluid delivery device 623 can drain the waste liquid from a plurality of ultrasonic cleaning tanks 51 through a waste liquid valve 622, and the arrangement of the pipeline structure is simple, and a plurality of ultrasonic cleaning tanks 51 share a drain assembly 62, thereby saving cost.
As shown in fig. 5, in some embodiments, an ultrasonic generator 512 is provided at the bottom of the ultrasonic cleaning tank 51, and the ultrasonic generator 512 is configured to provide sound field vibration to the cleaning liquid in the ultrasonic cleaning tank 51 to ultrasonically clean the target device at least partially inserted into the cleaning liquid. In some use cases, the ultrasonic generator 512 converts the received operating electricity into a high frequency ac electrical signal for driving, and converts the electrical power into mechanical power, i.e., ultrasonic waves for retransmission. Illustratively, the sonotrode 512 can be turned on and off, when turned on, the sonotrode 512 is operated, and when turned off, the sonotrode 512 is deactivated.
Because of the action of gravity, the dirty substances are more easily attached to the bottom of the ultrasonic cleaning tank 51, and the ultrasonic generator 512 is arranged at the bottom of the ultrasonic cleaning tank 51 in the embodiment, so that the bottom wall of the ultrasonic cleaning tank 51 vibrates greatly, and the dirty substances can be effectively prevented from being attached to the bottom wall of the ultrasonic cleaning tank 51. In addition, by adopting the bottom source mode, the gravity center of the ultrasonic generator 512 and the central axis of the ultrasonic cleaning tank 51 are on the same line, and the gravity center shift can not occur even if the ultrasonic cleaning tank is used for a long time.
It should be noted that, in other embodiments, the ultrasonic generator 512 may be disposed at a side of the ultrasonic cleaning tank 51.
As shown in fig. 2-5, in some embodiments, a drain assembly 62 is connected to a waste outlet 513 at the bottom of the ultrasonic cleaning tank 51 to facilitate draining of waste.
In some embodiments, the ultrasonic cleaning tank 51 includes an inner tank for containing cleaning liquid for ultrasonic cleaning of the target device, and a second fluid delivery device 623 connected to the inner tank for driving the discharge of waste liquid from the inner tank, and an outer tank disposed around the inner tank for receiving liquid overflowing from the inner tank. During cleaning of the target device, excess cleaning fluid may overflow from the top of the inner reservoir into the outer reservoir and drain through drain 514 of the outer reservoir.
In some embodiments, the waste liquid valve 622 has a plurality of inlets and an outlet, the plurality of inlets of the waste liquid valve 622 are correspondingly connected to the plurality of liquid outlet pipes 621, the outlet of the waste liquid valve 622 is connected to the second fluid conveying device 623, and the waste liquid valve 622 is used for switching and conducting the inlets in turn so as to discharge the waste liquid in the plurality of ultrasonic cleaning tanks 51 one by one. The arrangement adopts a waste liquid valve 622 with a plurality of inlets and an outlet, so that one second fluid conveying device 623 can discharge the waste liquid of a plurality of ultrasonic cleaning tanks 51 one by one, and the discharge is ensured to be clean.
As shown in fig. 1 and 4, the embodiment of the present utility model further proposes a sample analyzer 100, the proposed sample analyzer 100 includes a reaction device 70, a sample needle device 10, a reagent needle device 20, a stirring device 30, a measurement device 40, a non-ultrasonic cleaning device 110, an ultrasonic cleaning device 50, and a liquid path device 60, the reaction device 70 includes a plurality of placement sites for placing reaction cups, the sample needle device 10 includes a sample needle and a driving device thereof for dispensing a sample into the reaction cups, the reagent needle device 20 includes a reagent needle and a driving device thereof for dispensing a reagent into the reaction cups, the stirring device 30 includes a stirring rod and a driving device thereof for mixing a reaction liquid prepared from at least the sample and the reagent, the measurement device 40 is for measuring the reaction liquid, the non-ultrasonic cleaning device 110 is for cleaning a first target device including at least one of the reaction cups, the sample needle, the reagent needle, and the stirring rod, the ultrasonic cleaning device 50 is for accommodating a second target device at least partially inserted into the cleaning liquid, the second target device including the needle, the needle and the stirring rod is for injecting the reagent into the non-ultrasonic cleaning device 61, and the ultrasonic cleaning device 61 is provided for the stirring device 60 to the non-ultrasonic cleaning device 110.
The liquid supply assembly 61 includes a first liquid supply pipeline 616, a second liquid supply pipeline 617 and a first fluid conveying device 6111, the first liquid supply pipeline 616 is communicated with the ultrasonic cleaning device 50, the second liquid supply pipeline 617 is communicated with the non-ultrasonic cleaning device 110, the first liquid supply pipeline 616 and the second liquid supply pipeline 617 are both communicated with the first fluid conveying device 6111, and one first fluid conveying device 6111 is used for communicating a container containing a first cleaning liquid and driving the first cleaning liquid in the container containing the first cleaning liquid to be dispensed to the ultrasonic cleaning device 50 and the non-ultrasonic cleaning device 110. In this embodiment, the first fluid conveying device 6111 is a pressure source of the whole machine, and the setting mode adopts the pressure source of the whole machine to perform liquid injection for the ultrasonic cleaning device 50 and the non-ultrasonic cleaning device 110, so that a special pump is not required to be additionally arranged to perform liquid injection for the ultrasonic cleaning device 50, and the cost is saved.
In some embodiments, the non-ultrasonic cleaning device 110 may include a general cleaning tank for using a general mode cleaning, the general cleaning tank may be used for accommodating a cleaning liquid and performing general mode cleaning on a sample needle or a reagent needle or a stirring rod at least partially inserted into the cleaning liquid, the non-ultrasonic cleaning device 110 may further include a cleaning needle or a cleaning tube, and a driving device for driving the cleaning needle or the cleaning tube to move, and the first fluid delivery device 6111 delivers the cleaning liquid to the cleaning needle or the cleaning tube through a pipeline and ejects the cleaning liquid from the cleaning needle cleaning tube to the surface of the reaction cup for cleaning.
As shown in fig. 4, in some embodiments, the ultrasonic cleaning device 50 includes a plurality of ultrasonic cleaning tanks 51, and the first liquid supply line 616 may be in communication with the plurality of ultrasonic cleaning tanks 51 through the liquid inlet valve 6112, the first liquid distribution structure 612 and the plurality of liquid inlet pipes 613, so as to realize that one first fluid conveying device 6111 conveys the cleaning liquid to the plurality of ultrasonic cleaning tanks 51 through the first liquid supply line 616 and the one liquid inlet valve 6112 through the first liquid distribution structure 612 and the plurality of liquid inlet pipes 613.
As shown in fig. 1 and 4, the embodiment of the present utility model further proposes a sample analyzer 100, the proposed sample analyzer 100 includes a reaction device 70, a sample needle device 10, a reagent needle device 20, a stirring device 30, a measurement device 40, a liquid suction device 120, an ultrasonic cleaning device 50, and a liquid path device 60, the reaction device 70 includes a plurality of placement sites for placing reaction cups, the sample needle device 10 includes a sample needle and a driving device thereof for dispensing a sample into the reaction cups, the reagent needle device 20 includes a reagent needle and a driving device thereof for dispensing a reagent into the reaction cups, the stirring device 30 includes a stirring rod and a driving device thereof for mixing a reaction liquid, the reaction liquid is prepared from at least the sample and the reagent, the measurement device 40 is used for measuring the reaction liquid, the liquid suction device 120 is used for sucking a waste liquid in the reaction cups after cleaning, the ultrasonic cleaning device 50 is used for holding a cleaning liquid and performing ultrasonic cleaning on a target device at least partially inserted into the cleaning liquid, the target device includes at least one of the sample needle, the reagent needle and the stirring rod, the liquid path device 60 includes a liquid drain assembly 62, the liquid drain assembly 62 is used for draining the liquid waste device 120 and the ultrasonic cleaning device.
The drain assembly 62 includes a first drain pipe 624, a second drain pipe 625, and a second fluid delivery device 623, the first drain pipe 624 is connected to the ultrasonic cleaning device 50, the second drain pipe 625 is connected to the liquid suction device 120, the first drain pipe 624 and the second drain pipe 625 are both in communication with the second fluid delivery device 623, and the second fluid delivery device 623 is used for driving the liquid suction device 120 and the ultrasonic cleaning device 50 to drain the waste liquid. In this embodiment, the waste liquid of the liquid suction device 120 and the ultrasonic cleaning device 50 is discharged through the same second fluid conveying device 623, and a special pump is not required to be additionally arranged to discharge the waste liquid of the ultrasonic cleaning device 50, so that the cost is saved.
In some embodiments, the second fluid delivery device 623 includes a negative pressure source for providing negative pressure to draw waste fluid from the pipetting device 120 and the ultrasonic cleaning device 50. In this embodiment, the negative pressure source is a vacuum pressure source of the whole machine, and the arrangement mode adopts the vacuum pressure source of the whole machine to extract the waste liquid of the liquid suction device 120 and the ultrasonic cleaning device 50, so that the cost is saved. The pipetting device 120 may include a pipetting needle or a pipette and a driving device for driving the pipetting needle or the pipette to move, and the negative pressure source provides negative pressure to pump the waste liquid in the reaction cup after washing through the pipetting needle or the pipette.
In some embodiments, the second fluid delivery device 623 is also in communication with a common wash tank within the sample analyzer 100 for draining waste fluid from the common wash tank, which may be used to contain a wash liquid and perform a common mode wash on a sample needle or reagent needle or stirring rod at least partially inserted into the wash liquid.
As shown in fig. 4, in some embodiments, the ultrasonic cleaning apparatus 50 includes a plurality of ultrasonic cleaning tanks 51, and the first drain pipe 624 may be in communication with the plurality of ultrasonic cleaning tanks 51 through a multi-channel waste liquid valve 622 and a plurality of drain pipes 621 to realize that one second fluid delivery apparatus 623 discharges waste liquid of the plurality of ultrasonic cleaning tanks 51 through the first drain pipe 624 and the multi-channel waste liquid valve 622.
While the utility model has been described with reference to certain preferred embodiments, it will be understood by those skilled in the art that various changes and substitutions of equivalents may be made and equivalents will be apparent to those skilled in the art without departing from the scope of the utility model. Therefore, the protection scope of the utility model is subject to the protection scope of the claims.

Claims (12)

1. A sample analyzer, comprising:
a sample needle device comprising a sample needle and a driving device thereof for dispensing a sample;
a reagent needle device comprising a reagent needle and a driving device thereof for dispensing a reagent;
the stirring device comprises a stirring rod and a driving device thereof and is used for mixing a reaction liquid, wherein the reaction liquid is prepared from at least the sample and the reagent;
a measuring device for measuring the reaction liquid;
an ultrasonic cleaning apparatus including a plurality of ultrasonic cleaning tanks for holding a cleaning liquid and ultrasonically cleaning a target device at least partially inserted into the cleaning liquid, the target device including at least one of the sample needle, the reagent needle, and the stirring rod;
a liquid path apparatus comprising a liquid supply assembly for injecting a cleaning liquid into the plurality of ultrasonic cleaning tanks, wherein the liquid supply assembly comprises:
the liquid inlet structure is communicated with the ultrasonic cleaning tanks and comprises a first fluid conveying device, and one first fluid conveying device is used for communicating a container containing a first cleaning liquid and driving the first cleaning liquid in the container containing the first cleaning liquid to be distributed to the ultrasonic cleaning tanks.
2. The sample analyzer of claim 1, wherein the fluid supply assembly further comprises:
the first liquid separation structure comprises a first liquid inlet and a plurality of first liquid outlets, wherein the first liquid inlet is communicated with the liquid inlet structure, and the plurality of first liquid outlets are communicated with the plurality of ultrasonic cleaning tanks.
3. The sample analyzer of claim 2, wherein the fluid intake structure further comprises:
the liquid inlet valve is arranged between the first liquid separating structure and the first fluid conveying device and is used for cutting off or conducting the liquid inlet structure, and one first fluid conveying device is used for driving the first cleaning liquid in the container filled with the first cleaning liquid to enter the first liquid separating structure through one liquid inlet valve and be distributed to the plurality of ultrasonic cleaning tanks.
4. The sample analyzer of claim 2, wherein the number of liquid feed structures is at least two, each of the at least two liquid feed structures is in communication with the first liquid feed port, each of the liquid feed structures is configured to deliver a cleaning liquid to the plurality of ultrasonic cleaning reservoirs, and the types of cleaning liquids delivered by the at least two liquid feed structures are different.
5. The sample analyzer of claim 4, wherein the fluid supply assembly further comprises a second fluid separation structure comprising:
the second liquid outlet is communicated with the first liquid inlet;
the at least two second liquid inlets are correspondingly communicated with the at least two liquid inlet structures, so that each liquid inlet structure can convey cleaning liquid to the plurality of ultrasonic cleaning tanks, and the types of the cleaning liquid conveyed by the at least two liquid inlet structures are different.
6. The sample analyzer of claim 1, further comprising a drain assembly, the drain assembly comprising:
the liquid outlet pipes are connected with one ultrasonic cleaning tank;
the waste liquid valve is connected with the liquid outlet pipe and used for stopping or switching on the liquid outlet pipe;
the second fluid conveying device is connected with the waste liquid valve and is used for driving the waste liquid in the ultrasonic cleaning tanks to be discharged;
the liquid outlet pipes are connected to the same liquid outlet valve, the liquid outlet valve is provided with a plurality of inlets and an outlet, the inlets of the liquid outlet valve are correspondingly connected with the liquid outlet pipes, the outlet of the liquid outlet valve is connected to the second fluid conveying device, and the liquid outlet valve is used for sequentially switching on the inlets so as to discharge the liquid outlet in the ultrasonic cleaning tanks one by one.
7. A sample analyzer, comprising:
a sample needle device comprising a sample needle and a driving device thereof for dispensing a sample;
a reagent needle device comprising a reagent needle and a driving device thereof for dispensing a reagent;
the stirring device comprises a stirring rod and a driving device thereof and is used for mixing a reaction liquid, wherein the reaction liquid is prepared from at least the sample and the reagent;
a measuring device for measuring the reaction liquid;
an ultrasonic cleaning apparatus including a plurality of ultrasonic cleaning tanks for holding a cleaning liquid and ultrasonically cleaning a target device at least partially inserted into the cleaning liquid, the target device including at least one of the sample needle, the reagent needle, and the stirring rod;
the liquid way device, including flowing back subassembly, flowing back subassembly is used for discharging the waste liquid in a plurality of ultrasonic cleaning ponds, wherein, flowing back subassembly includes:
the liquid outlet pipes are connected with one ultrasonic cleaning tank;
the liquid outlet valves are connected with the same liquid outlet valve and are used for cutting off or conducting the liquid outlet pipes;
And the second fluid conveying device is connected with the waste liquid valve and is used for driving the waste liquid in the ultrasonic cleaning tanks to be discharged.
8. The sample analyzer of claim 7,
an ultrasonic generator is arranged at the bottom of the ultrasonic cleaning pool and is used for providing sound field vibration for the cleaning liquid in the ultrasonic cleaning pool so as to carry out ultrasonic cleaning on the target device at least partially inserted into the cleaning liquid; and/or the number of the groups of groups,
the liquid draining component is connected to the bottom of the ultrasonic cleaning tank; and/or the number of the groups of groups,
the ultrasonic cleaning tank comprises an inner tank and an outer tank, the inner tank is used for containing cleaning liquid for ultrasonic cleaning of the target device, the second fluid conveying device is communicated with the inner tank so as to drive waste liquid in the inner tank to be discharged, and the outer tank is arranged on the inner tank in a surrounding mode and is used for receiving liquid overflowed from the inner tank.
9. The sample analyzer of claim 7, wherein the waste liquid valve has a plurality of inlets and an outlet, the plurality of inlets of the waste liquid valve are correspondingly connected to the plurality of liquid outlet pipes, the outlet of the waste liquid valve is connected to the second fluid conveying device, and the waste liquid valve is used for switching on each inlet in turn so as to discharge waste liquid in the plurality of ultrasonic cleaning tanks one by one.
10. A sample analyzer, comprising:
the reaction device comprises a plurality of placement positions, wherein the placement positions are used for placing reaction cups;
a sample needle device comprising a sample needle and a drive device thereof for dispensing a sample to the cuvette;
a reagent needle device comprising a reagent needle and a driving device thereof for dispensing a reagent into the reaction cup;
the stirring device comprises a stirring rod and a driving device thereof and is used for mixing a reaction liquid, wherein the reaction liquid is prepared from at least the sample and the reagent;
a measuring device for measuring the reaction liquid;
a non-ultrasonic cleaning device for cleaning a first target device with a cleaning liquid, the first target device comprising at least one of the cuvette, the sample needle, the reagent needle, and the stirring rod;
an ultrasonic cleaning device for containing a cleaning liquid and ultrasonically cleaning a second target device at least partially inserted into the cleaning liquid, the second target device including at least one of the sample needle, the reagent needle, and the stirring rod;
liquid path device, including the confession liquid subassembly, the confession liquid subassembly is used for to non-ultrasonic cleaning device with ultrasonic cleaning device pours into the washing liquid into, wherein, the confession liquid subassembly includes:
The first liquid supply pipeline is communicated with the ultrasonic cleaning device;
the second liquid supply pipeline is communicated with the non-ultrasonic cleaning device;
the first fluid conveying device is used for communicating a container containing first cleaning fluid and driving the first cleaning fluid in the container containing the first cleaning fluid to be dispensed to the ultrasonic cleaning device and the non-ultrasonic cleaning device.
11. A sample analyzer, comprising:
the reaction device comprises a plurality of placement positions, wherein the placement positions are used for placing reaction cups;
a sample needle device comprising a sample needle and a drive device thereof for dispensing a sample to the cuvette;
a reagent needle device comprising a reagent needle and a driving device thereof for dispensing a reagent into the reaction cup;
the stirring device comprises a stirring rod and a driving device thereof and is used for mixing a reaction liquid, wherein the reaction liquid is prepared from at least the sample and the reagent;
a measuring device for measuring the reaction liquid;
the liquid suction device is used for sucking the waste liquid in the reaction cup after cleaning;
An ultrasonic cleaning device for containing a cleaning liquid and ultrasonically cleaning a target device at least partially inserted into the cleaning liquid, the target device including at least one of the sample needle, the reagent needle, and the stirring rod;
the liquid way device, including flowing back subassembly, flowing back subassembly is used for discharging the waste liquid of pipetting device with ultrasonic cleaning device, wherein, flowing back subassembly includes:
the first liquid discharge pipeline is connected with the ultrasonic cleaning device;
the second liquid draining pipeline is connected with the liquid absorbing device;
and the second fluid conveying device is used for driving the liquid suction device and the ultrasonic cleaning device to discharge waste liquid.
12. The sample analyzer of claim 11, wherein the second fluid transport device comprises a negative pressure source for providing a negative pressure to draw waste fluid from the pipetting device and the ultrasonic cleaning device.
CN202222627044.XU 2022-09-29 2022-09-29 Sample analyzer Active CN218956599U (en)

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CN202222627044.XU CN218956599U (en) 2022-09-29 2022-09-29 Sample analyzer

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Application Number Priority Date Filing Date Title
CN202222627044.XU CN218956599U (en) 2022-09-29 2022-09-29 Sample analyzer

Publications (1)

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CN218956599U true CN218956599U (en) 2023-05-02

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