CN218879926U

CN218879926U - Cell bio-genetic engineering is with bio-pharmaceuticals stem cell reaction equipment

Info

Publication number: CN218879926U
Application number: CN202222864541.1U
Authority: CN
Inventors: 杨虎子
Original assignee: Cerogon Shanghai Medical Technology Co ltd
Current assignee: Cerogon Shanghai Medical Technology Co ltd
Priority date: 2022-10-29
Filing date: 2022-10-29
Publication date: 2023-04-18
Anticipated expiration: 2032-10-29

Abstract

The utility model discloses a cell bio-genetic engineering is with bio-pharmaceuticals stem cell response device relates to bioengineering technical field, the on-line screen storage device comprises a base, the last fixed surface of base is connected with a plurality of solid fixed cylinder, and is a plurality of the inner wall swing joint of solid fixed cylinder has a telescopic cylinder, telescopic cylinder's top fixedly connected with workstation, telescopic cylinder's inner wall has cup jointed the spring, the last fixed surface of workstation is connected with reaction box and box, the equal fixed mounting in both sides of reaction box has ball bearing, ball bearing's inner wall fixed connection has the gear shaft. This cell bio-genetic engineering is with bio-pharmaceuticals stem cell response device drives the rotation axis rotation through servo motor's output shaft, and the rotation axis drives gear shaft rotation through first take-up pulley, second take-up pulley and flat drive, and the gear shaft drives the rotation of retort and stirring leaf, accomplishes the homogeneous mixing to the cell sap to can not smash the stem cell in the cell sap.

Description

Cell bio-genetic engineering is with bio-pharmaceuticals stem cell reaction equipment

Technical Field

The utility model relates to the technical field of bioengineering, in particular to a cell bio-genetic engineering bio-pharmaceutical stem cell reaction device.

Background

The stem cell is a cell with self-replicating function and multidirectional differentiation potential, can regenerate various cells, tissues or organs of a human body under specific conditions, is called as a 'universal cell' in the medical field, has important significance in basic research and transformation medical application, has wide application prospects in the fields of regenerative medicine, disease models, drug screening, precise medicine and the like, the cell culture technology is the most core and basic technology in the biotechnology, and when the cell is cultured in vitro, a bioreactor is a key device in the whole culture process, provides a proper growth environment for the cell, enables the cell to be rapidly proliferated and form a required biological tissue product, and the existing stem cell reaction equipment is easy to break the stem cell in cell sap in the stirring process, so that incomplete reaction is caused, and the reaction result is influenced.

In the patent application number of the Chinese utility model: CN202022679169.8 discloses a cell bio-genetic engineering is with bio-pharmaceuticals stem cell response equipment, and the structure includes the base and locates the retort body on the base, the bottom of base is fixed with the support column, and the below of base is fixed with driving motor, and the discharge gate has still been seted up to the base, the top of retort body is trapezoidal that has the open-ended, and is equipped with the auxiliary material valve on trapezoidal inclined plane. The bio-pharmaceutical stem cell reaction equipment for cell bio-genetic engineering can easily break stem cells in cell sap in the stirring process, so that incomplete reaction is caused, and the reaction result is influenced.

Therefore, it is necessary to provide a bio-pharmaceutical stem cell reaction apparatus for cell bio-genetic engineering to solve the above problems.

SUMMERY OF THE UTILITY MODEL

Technical problem to be solved

An object of the utility model is to provide a cell bio-genetic engineering is with bio-pharmaceuticals stem cell response device to solve the current cell bio-genetic engineering for bio-pharmaceuticals stem cell response device that proposes in the above-mentioned background art, at the stirring in-process, smash the stem cell in the cell sap easily, lead to the reaction not thorough, influence the problem of reaction result.

(II) technical scheme

In order to achieve the above purpose, the utility model discloses a following technical scheme realizes: the utility model provides a cell bio-genetic engineering is with bio-pharmaceuticals stem cell response device, includes the base, the last fixed surface of base is connected with a plurality of solid fixed cylinder, and is a plurality of the inner wall swing joint of solid fixed cylinder has a telescopic cylinder, the top fixedly connected with workstation of telescopic cylinder, the spring has been cup jointed to the inner wall of telescopic cylinder, the last fixed surface of workstation is connected with reaction box and box, the equal fixed mounting in both sides of reaction box has ball bearing, ball bearing's inner wall fixed connection has the gear shaft, the one end fixedly connected with retort of gear shaft, the inner wall fixedly connected with stirring leaf of retort, the first tensioning wheel of outer wall fixedly connected with of gear shaft, swing joint has the flat belt in the first tensioning wheel, the one end swing joint that first tensioning wheel was kept away from in the flat belt has the second take-up pulley, the inner wall fixedly connected with rotation axis of second take-up pulley, the one end fixedly connected with servo motor of rotation axis.

Preferably, a plurality of the fixed cylinders are distributed in a circular array.

Preferably, the two ends of the spring are respectively fixedly connected with the base and the workbench, and the workbench is movably connected with the base.

Preferably, the upper surface of the workbench is fixedly connected with an observation table, and the upper surface of the observation table is movably connected with a culture dish.

Preferably, the reaction box and the box body are fixedly connected.

Preferably, an inlet and an outlet are formed in both sides of the reaction tank, and the inner walls of the inlet and the outlet are movably connected with a cover cap.

Preferably, the top of the reaction box is movably connected with a funnel, and the outer wall of the reaction box is movably connected with a protective door through a shaft.

Preferably, the rotating shaft is movably connected with the box body.

Preferably, the servo motor is fixedly connected with the workbench.

(III) advantageous effects

Compared with the prior art, the utility model provides a cell bio-genetic engineering is with bio-pharmaceuticals stem cell response device possesses following beneficial effect:

1. this cell bio-genetic engineering is with bio-pharmaceuticals stem cell response device drives the rotation axis rotation through servo motor's output shaft, and the rotation axis drives the gear shaft rotation through first take-up pulley, second take-up pulley and flat drive, and the gear shaft drives the rotation of retort and stirring leaf, accomplishes the homogeneous mixing to the cell liquid to can not smash the stem cell in the cell liquid.

2. This cell bio-genetic engineering is with bio-pharmaceuticals stem cell response device through set up solid fixed cylinder, telescopic cylinder and spring between base and workstation, can reduce vibrations and sound that reaction unit brought, has improved the practicality of device.

Drawings

Fig. 1 is a first perspective view of the structure of the present invention;

fig. 2 is a second perspective view of the structure of the present invention;

FIG. 3 is a schematic perspective view of the inner structure of the structural box of the present invention;

FIG. 4 is a first schematic perspective cross-sectional view of the structure of the present invention;

fig. 5 is a second schematic perspective cross-sectional view of the structure of the present invention;

fig. 6 is an enlarged schematic view of the structure of the area a in fig. 4 according to the present invention.

In the figure: 1. a base; 2. a work table; 3. a fixed cylinder; 4. a telescopic cylinder; 5. a spring; 6. an observation stage; 7. a culture dish; 8. a reaction box; 9. a box body; 10. a reaction tank; 11. stirring blades; 12. an inlet and an outlet; 13. a funnel; 14. capping; 15. a gear shaft; 16. a ball bearing; 17. a first tensioning wheel; 18. a second tensioning wheel; 19. flattening the belt; 20. a rotating shaft; 21. a servo motor; 22. a protective door.

Detailed Description

The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments.

Referring to fig. 1-6, a bio-pharmaceutical stem cell reaction device for cell bio-genetic engineering, comprising a base 1, a plurality of fixed cylinders 3 fixedly connected to the upper surface of the base 1, the plurality of fixed cylinders 3 distributed in a circular array, a telescopic cylinder 4 movably connected to the inner wall of the plurality of fixed cylinders 3, a worktable 2 fixedly connected to the top end of the telescopic cylinder 4, a spring 5 sleeved on the inner wall of the telescopic cylinder 4, both ends of the spring 5 respectively fixedly connected to the base 1 and the worktable 2, the worktable 2 movably connected to the base 1, the fixed cylinders 3, the telescopic cylinders 4 and the spring 5 arranged between the base 1 and the worktable 2 can reduce the vibration and sound caused by the reaction device, improve the practicability of the device, an observation platform 6 fixedly connected to the upper surface of the worktable 2, a culture dish 7 movably connected to the upper surface of the observation platform 6, the culture dish 7 being a cell culture dish 7, glass is used as a material and can be used for culturing plant cells, microorganisms and animal cells, the upper surface of a workbench 2 is fixedly connected with a reaction box 8 and a box body 9, the reaction box 8 is fixedly connected with the box body 9, the box body 9 is semi-wrapped on the reaction box 8 and can prevent internal mechanical damage to external personnel, both sides of the reaction box 8 are fixedly provided with ball bearings 16, the inner wall of each ball bearing 16 is fixedly connected with a gear shaft 15, one end of each gear shaft 15 is fixedly connected with a reaction tank 10, the inner wall of each reaction tank 10 is fixedly connected with a stirring blade 11, the stirring blade 11 adopts a spiral structure, each stirring blade 11 is an axial flow type high-performance stirrer with a wide application range, the discharge performance is good, the shearing force is low, both sides of the reaction tank 10 are provided with an inlet and an outlet 12, the inner wall of the inlet and outlet 12 is movably connected with a cover cap 14, and the top of the reaction box 8 is movably connected with a funnel 13, the cell sap is poured into the reaction tank 10 through the funnel 13, then the funnel 13 is moved away, the cap 14 is placed into the inlet and outlet 12, the outer wall of the reaction tank 8 is movably connected with a protective door 22 through a shaft, the protective door 22 is made of glass, the condition of the cell sap in the culture dish 7 on the reaction tank 8 can be observed through the protective door 22, the outer wall of the gear shaft 15 is fixedly connected with a first tensioning wheel 17, a flat belt 19 is movably connected in the first tensioning wheel 17, one end of the flat belt 19, which is far away from the first tensioning wheel 17, is movably connected with a second tensioning wheel 18, the inner wall of the second tensioning wheel 18 is fixedly connected with a rotating shaft 20, two ends of the rotating shaft 20 are respectively provided with the first tensioning wheel 18, the second tensioning wheel 17 and the flat belt 19, the reaction tank 10 can stably rotate, the center of gravity does not deviate, the rotating shaft 20 is movably connected with the tank body 9, one end of the rotating shaft 20 is fixedly connected with a servo motor 21, the servo motor 21 is fixedly connected with the working platform 2, the rotating shaft 20 is driven by an output shaft of the servo motor 21, the rotating shaft 20 is driven by the first tensioning wheel 17, the second tensioning wheel 18 and the flat belt 19, the gear shaft 15 and the cell sap can not uniformly mix the cell sap, and the dry cell sap in the reaction tank 10 and the mixing of the stirring shaft 11 can be uniformly crushed.

The electrical components in the document are electrically connected with an external master controller and 220V mains supply, and the master controller can be a computer or other conventional known devices for playing a role in control.

The working principle is as follows: the cell sap is poured into a reaction tank 10 from an inlet and an outlet 12 through a funnel 13, the funnel 13 is removed, a cap 14 is placed into the inlet and the outlet 12, a servo motor 21 is started, an output shaft of the servo motor 21 drives a rotating shaft 20 in a box body 9 to rotate, the rotating shaft 20 drives a second tensioning wheel 18 to rotate, the second tensioning wheel 18 drives a first tensioning wheel 17 to rotate through a flat belt 19, the first tensioning wheel 17 drives a gear shaft 15 to rotate, the gear shaft 15 rotates in a ball bearing 16 to drive the reaction tank 10 and a stirring blade 11 to rotate, a damping device formed by matching a fixed cylinder 3, a telescopic cylinder 4 and a spring 5 between a base 1 and a workbench 2 can reduce vibration and sound brought by the reaction device, after stirring reaction is completed, a protective door 22 in the reaction tank 8 is opened, a culture dish 7 is placed on an observation platform 6, the inlet and the outlet 12 at the bottom end of the reaction tank 10 is opened, and the cell sap after the reaction is completed is poured into the culture dish 7.

Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.

Claims

1. The utility model provides a cell bio-genetic engineering is with bio-pharmaceuticals stem cell response device, includes base (1), its characterized in that: the utility model discloses a quick-witted, including base (1), the last fixed surface of base (1) is connected with a plurality of solid fixed cylinder (3), and is a plurality of the inner wall swing joint of solid fixed cylinder (3) has telescopic cylinder (4), the top fixedly connected with workstation (2) of telescopic cylinder (4), spring (5) have been cup jointed to the inner wall of telescopic cylinder (4), the last fixed surface of workstation (2) is connected with reaction box (8) and box (9), the equal fixed mounting in both sides of reaction box (8) has ball bearing (16), the inner wall fixed connection of ball bearing (16) has gear shaft (15), the one end fixedly connected with retort (10) of gear shaft (15), the inner wall fixedly connected with stirring leaf (11) of retort (10), the first take-up pulley (17) of outer wall fixedly connected with of gear shaft (15), swing joint has flat belt (19) in first take-up pulley (17), the one end that first take-up pulley (17) was kept away from in flat belt (19) is connected with second take-up pulley (18), the inner wall fixedly connected with rotation axis (20) of second take-up pulley (18), the one end fixed connection of rotation axis (20) is connected with servo motor (21).

2. The biopharmaceutical stem cell reaction device for cell bio-genetic engineering according to claim 1, wherein: the fixed cylinders (3) are distributed in a circular array.

3. The biopharmaceutical stem cell reaction device for cell bio-genetic engineering according to claim 1, wherein: the two ends of the spring (5) are fixedly connected with the base (1) and the workbench (2) respectively, and the workbench (2) is movably connected with the base (1).

4. The biopharmaceutical stem cell reaction device for cell bio-genetic engineering according to claim 1, wherein: the upper surface fixed connection of workstation (2) has observation platform (6), the upper surface swing joint of observation platform (6) has culture dish (7).

5. The biopharmaceutical stem cell reaction device for cell bio-genetic engineering according to claim 1, wherein: the reaction box (8) is fixedly connected with the box body (9).

6. The biopharmaceutical stem cell reaction device for cell bio-genetic engineering according to claim 1, wherein: the reactor is characterized in that an inlet and an outlet (12) are formed in both sides of the reaction tank (10), and the inner walls of the inlet and the outlet (12) are movably connected with a cover cap (14).

7. The biopharmaceutical stem cell reaction device for cell bio-genetic engineering according to claim 1, wherein: the top of reaction box (8) swing joint has funnel (13), the outer wall of reaction box (8) has guard gate (22) through axle swing joint.

8. The biopharmaceutical stem cell reaction device for cell bio-genetic engineering according to claim 1, wherein: the rotating shaft (20) is movably connected with the box body (9).

9. The biopharmaceutical stem cell reaction device for cell bio-genetic engineering according to claim 1, wherein: the servo motor (21) is fixedly connected with the workbench (2).