CN213924862U - Bio-pharmaceuticals stem cell reaction equipment for cell biological gene engineering - Google Patents
Bio-pharmaceuticals stem cell reaction equipment for cell biological gene engineering Download PDFInfo
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- CN213924862U CN213924862U CN202021867741.7U CN202021867741U CN213924862U CN 213924862 U CN213924862 U CN 213924862U CN 202021867741 U CN202021867741 U CN 202021867741U CN 213924862 U CN213924862 U CN 213924862U
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Abstract
The utility model discloses a cell bio-genetic engineering is with bio-pharmaceuticals stem cell response device, including the biological reaction jar, biological reaction jar one end is equipped with the pipeline mouth that is linked together, and the biological reaction jar inner chamber is equipped with tubular static mixer, tubular static mixer's mouth of pipe both ends are connected with the one end of first connecting cylinder and the one end of second connecting cylinder respectively. This cell bio-genetic engineering is with bio-pharmaceuticals stem cell response device is equipped with the second connecting cylinder, it can let the cell liquid that gets into the biological reaction jar obtain the automatic stirring mixed effect of tubular static mixer, the stirring efficiency to the cell liquid has been improved, it is convenient to make its stirring process, and the device is equipped with first connecting cylinder, the diffluence orifice of first connecting cylinder and second connecting cylinder, can play certain branch work effect to tubular static mixer, let the cell liquid obtain mixed effect at the reposition of redundant personnel in-process, let the comprehensive result of use of biological reaction jar strengthened.
Description
Technical Field
The utility model relates to a biological cell response device field specifically is a cell bio-genetic engineering is with bio-pharmaceuticals stem cell response device.
Background
Stem cells are cells having self-replicating function and multi-directional differentiation potential, and can regenerate into various cells, tissues or organs of the human body under specific conditions, and are called "universal cells" in the medical field. The stem cells have important significance in basic research and transformation medical application, and have wide application prospects in the fields of regenerative medicine, disease models, drug screening, precise medicine and the like. The cell culture technology is the most core and basic technology in the biotechnology, and when the cells are cultured in vitro, the bioreactor is the key equipment in the whole culture process, and provides a proper growth environment for the cells, so that the cells can be rapidly proliferated and form the required biological tissue product.
The existing biological pharmacy stem cell reaction equipment is inconvenient to mix and shake cell liquid in the reaction equipment, and the biological pharmacy stem cell reaction equipment for cell biological genetic engineering with the patent number of CN201920865642.6 makes the cell liquid in the reaction tank fully mixed evenly, but the device mixing process is too tedious, and the mixing efficiency is improved limitedly, so that the prior art has the defects that the improvement needs to be carried out.
SUMMERY OF THE UTILITY MODEL
An object of the utility model is to provide a cell bio-genetic engineering is with bio-pharmaceuticals stem cell response device to solve the not good problem of cell liquid mixed mode in the retort that provides among the above-mentioned background art.
In order to achieve the above object, the utility model provides a following technical scheme: the utility model provides a cell bio-genetic engineering is with bio-pharmaceuticals stem cell response device, includes biological reaction jar, biological reaction jar one end is equipped with the pipeline mouth that is linked together, and biological reaction jar inner chamber is equipped with tubular static mixer, tubular static mixer's mouth of pipe both ends are connected with the one end of first connecting cylinder and the one end of second connecting cylinder respectively, and first connecting cylinder and second connecting cylinder all set up to hopper type structure to the other end of second connecting cylinder and the other end of first connecting cylinder are connected with biological reaction jar inner wall side end, all be provided with the diffluence hole on first connecting cylinder and the second connecting cylinder, and the diffluence hole dislocation between it is parallel.
Preferably, both ends all are fixed with the mount about the biological reaction jar outer wall, and the mount alternates through the pivot and rotates and be connected with the pulley to the pulley contacts with solid fixed ring inner wall.
Preferably, solid fixed ring bottom mounting has the supporting seat, and the supporting seat sets up to "L" type structure to alternate in the montant of supporting seat and be used for connecting the one end at the connecting axle at biological reaction jar center.
Preferably, the other end fixedly connected with rocker of connecting axle, and the rocker sets up to "Z" type structure to one of them section horizontal pole one end of rocker sets up to the arc structure.
Preferably, the outer wall of the pipeline opening is in a thread structure, and a matched gland is spirally sleeved on the outer wall of the pipeline opening.
Preferably, the top end of the inner wall of the gland is fixedly glued with a rubber pad.
Compared with the prior art, the beneficial effects of the utility model are that: this cell bio-genetic engineering is with bio-pharmaceuticals stem cell response device is equipped with the second connecting cylinder, it can let the cell liquid that gets into the biological reaction jar obtain the automatic stirring mixed effect of tubular static mixer, the stirring efficiency to the cell liquid has been improved, it is convenient to make its stirring process, and the device is equipped with first connecting cylinder, the diffluence orifice of first connecting cylinder and second connecting cylinder, can play certain branch work effect to tubular static mixer, let the cell liquid obtain mixed effect at the reposition of redundant personnel in-process, let the comprehensive result of use of biological reaction jar strengthened.
Drawings
FIG. 1 is a diagram of a stem cell reaction apparatus for bio-pharmaceuticals for cell bio-genetic engineering according to the present invention;
FIG. 2 is an enlarged view of the portion A of FIG. 1 of a bio-pharmaceutical stem cell reaction apparatus for cell bio-genetic engineering according to the present invention;
FIG. 3 is a schematic view of the fixing ring connecting pulley of the bio-pharmaceutical stem cell reaction device for cell bio-genetic engineering of the present invention.
In the figure: 1. biological reaction jar, 2, tubular static mixer, 3, solid fixed ring, 4, pulley, 5, mount, 6, rocker, 7, connecting axle, 8, supporting seat, 9, pipeline mouth, 10, cushion, 11, gland, 12, first connecting cylinder, 13, second connecting cylinder.
Detailed Description
The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention.
Referring to fig. 1-3, the present invention provides a technical solution: a cell bio-genetic engineering bio-pharmaceutical stem cell reaction device comprises a bio-reaction tank 1, a tubular static mixer 2, a fixing ring 3, a pulley 4, a fixing frame 5, a rocker 6, a connecting shaft 7, a supporting seat 8, a pipeline port 9, a rubber mat 10, a gland 11, a first connecting cylinder 12 and a second connecting cylinder 13, wherein one end of the bio-reaction tank 1 is provided with the pipeline port 9 communicated with each other, the inner cavity of the bio-reaction tank 1 is provided with the tubular static mixer 2, the upper end and the lower end of the outer wall of the bio-reaction tank 1 are both fixed with the fixing frame 5, the fixing frame 5 is in alternate rotating connection with the pulley 4 through a rotating shaft, the pulley 4 is in contact with the inner wall of the fixing ring 3, the pulley 4 rotates along with the friction of the fixing ring 3 along with the rotation of the bio-reaction tank 1, the rotating track of the bio-reaction tank 1 is supported by sliding, so that the rotating process is more stable, the supporting seat 8 is fixed at the bottom end of the fixing ring 3, the supporting seat 8 is set to be L-shaped structure, and one end of a connecting shaft 7 used for connecting the center of the biological reaction tank 1 is inserted into a vertical rod of the supporting seat 8, the biological reaction tank 1 can rotate through the connecting shaft 7 to enable cell liquid to repeatedly pass through the tubular static mixer 2 to be stirred for many times so as to improve the stirring effect, meanwhile, the position of a pipeline opening 9 is flexibly changed through the rotation of the biological reaction tank 1, the charging and discharging operation of the cell liquid is convenient and efficient, the other end of the connecting shaft 7 is fixedly connected with a rocker 6, the rocker 6 is set to be Z-shaped structure, one end of one section of a cross rod of the rocker 6 is set to be arc-shaped structure, the rocker 6 is convenient to be stressed, the rotating operation of the connecting shaft 7 and the biological reaction tank 1 is convenient and labor-saving, the outer wall of the pipeline opening 9 is set to be thread-shaped structure, a matched gland 11 is spirally sleeved on the outer wall of the pipeline opening, and the gland 11 and the pipeline opening 9 are mutually in spiral clamping structure, this structural connection is firm, and easy dismounting, the efficiency of the business turn over material of cell liquid has further been improved, 11 inner wall top plys of gland are fixed with cushion 10, cushion 10 can increase the sealed effect of pipeline mouth 9, avoid pipeline mouth 9 to cause the condition emergence that the liquid spilled over along with the angular variation of biological reaction jar 1, the mouth of pipe both ends of tubular static mixer 2 are connected with the one end of first connecting cylinder 12 and the one end of second connecting cylinder 13 respectively, and first connecting cylinder 12 and second connecting cylinder 13 all set up to hopper type structure, and the other end of second connecting cylinder 13 and the other end of first connecting cylinder 12 are connected with 1 inner wall side of biological reaction jar, all be provided with the reposition of redundant personnel hole on first connecting cylinder 12 and the second connecting cylinder 13, and the reposition of redundant personnel hole dislocation between them is parallel.
The working principle is as follows: when the biopharmaceutical stem cell reaction device for cell bio-genetic engineering is used, firstly, the gland 11 is spirally taken down from the pipeline opening 9, the cell liquid to be reacted is input into the biological reaction tank 1 from the pipeline opening 9, in the process, part of the cell liquid enters the tubular static mixer 2 through the second connecting cylinder 13 to be mixed, meanwhile, the other part of the cell liquid enters the tank body of the biological reaction tank 1 from the shunting hole of the first connecting cylinder 12 through the shunting hole of the second connecting cylinder 13, then, the connecting shaft 7 is shaken through the rocker 6, the connecting shaft 7 is forced to move to drive the biological reaction tank 1 to rotate, the biological reaction tank 1 rotates to drive the pulley 4 and the fixed ring 3 to rotate in a friction manner through the fixed frame 5, then, the cell liquid sinking into the bottom of the biological reaction tank 1 enters the tubular static mixer 2 again through the first connecting cylinder 12 to be stirred, and then, the cell liquid in the biological reaction tank 1 is enabled to be increased by the tubular static mixer 2 along with the rotation effect of the biological reaction tank 1 The cell liquid in the biological reaction tank 1 is fully mixed by secondary stirring, so that the cell reaction efficiency can be improved, and the cell reaction efficiency is the using process of the biological pharmacy stem cell reaction equipment for the cell biological gene engineering.
Although the present invention has been described in detail with reference to the foregoing embodiments, it will be apparent to those skilled in the art that modifications may be made to the embodiments or portions thereof without departing from the spirit and scope of the invention.
Claims (6)
1. The utility model provides a cell bio-genetic engineering is with bio-pharmaceuticals stem cell response device, includes biological reaction jar (1), biological reaction jar (1) one end is equipped with pipeline mouth (9) that are linked together, and biological reaction jar (1) inner chamber is equipped with tubular static mixer (2), its characterized in that: the pipe orifice both ends of tubular static mixer (2) are connected with the one end of first connecting cylinder (12) and the one end of second connecting cylinder (13) respectively, and just first connecting cylinder (12) and second connecting cylinder (13) all set up to hopper type structure to the other end of second connecting cylinder (13) and the other end of first connecting cylinder (12) are connected with biological reaction jar (1) inner wall side, all be provided with the reposition of redundant personnel hole on first connecting cylinder (12) and the second connecting cylinder (13), and the reposition of redundant personnel hole dislocation between it is parallel.
2. The apparatus for stem cell reaction in biopharmaceuticals for cell bio-genetic engineering according to claim 1, wherein: both ends all are fixed with mount (5) about biological reaction jar (1) outer wall, and mount (5) alternate through the pivot and rotate and be connected with pulley (4) to pulley (4) contact with solid fixed ring (3) inner wall.
3. The apparatus for stem cell reaction in biopharmaceuticals for cell bio-genetic engineering according to claim 2, wherein: fixed ring (3) bottom mounting has supporting seat (8), and supporting seat (8) set up to "L" type structure to alternate in the montant of supporting seat (8) and be used for connecting the one end at connecting axle (7) at biological reaction jar (1) center.
4. The apparatus for stem cell reaction in biopharmaceuticals for cell bio-genetic engineering according to claim 3, wherein: the other end fixedly connected with rocker (6) of connecting axle (7), and rocker (6) set up to "Z" type structure to one of them section horizontal pole one end of rocker (6) sets up to the arc structure.
5. The apparatus for stem cell reaction in biopharmaceuticals for cell bio-genetic engineering according to claim 1, wherein: the outer wall of the pipeline port (9) is in a thread structure, and a matched gland (11) is spirally sleeved on the outer wall of the pipeline port.
6. The apparatus for stem cell reaction in biopharmaceuticals for cell bio-genetic engineering according to claim 5, wherein: and a rubber pad (10) is glued and fixed at the top end of the inner wall of the gland (11).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202021867741.7U CN213924862U (en) | 2020-09-01 | 2020-09-01 | Bio-pharmaceuticals stem cell reaction equipment for cell biological gene engineering |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202021867741.7U CN213924862U (en) | 2020-09-01 | 2020-09-01 | Bio-pharmaceuticals stem cell reaction equipment for cell biological gene engineering |
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| Publication Number | Publication Date |
|---|---|
| CN213924862U true CN213924862U (en) | 2021-08-10 |
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| CN202021867741.7U Active CN213924862U (en) | 2020-09-01 | 2020-09-01 | Bio-pharmaceuticals stem cell reaction equipment for cell biological gene engineering |
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Address after: 116000 No. 103-9-3, 1f, block a, overseas students entrepreneurship Park, No. 1, Torch Road, high tech Industrial Park, Dalian, Liaoning Patentee after: Dalian Cixing Bencao Nutrition Technology Co.,Ltd. Address before: 116000 No. 103-9-3, 1f, block a, overseas students entrepreneurship Park, No. 1, Torch Road, high tech Industrial Park, Dalian, Liaoning Patentee before: Dalian Shanhai Wuhua Science and Technology Development Co.,Ltd. |
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