CN218860745U - Quantitative glue sealing device - Google Patents
Quantitative glue sealing device Download PDFInfo
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- CN218860745U CN218860745U CN202222984644.1U CN202222984644U CN218860745U CN 218860745 U CN218860745 U CN 218860745U CN 202222984644 U CN202222984644 U CN 202222984644U CN 218860745 U CN218860745 U CN 218860745U
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Abstract
The utility model relates to a mounting glue technical field, aiming at the problem that the sealing glue extrusion amount is difficult to control in the hybridization process of the prior FISH experimental species, the utility model provides a quantitative sealing glue device, which comprises a sealing glue box body, wherein the sealing glue box body is provided with a plurality of horizontally distributed plate placing drawers, and a glue outlet component is arranged at the top of the sealing glue box body; the glue outlet assembly comprises a plurality of glue outlet pipelines and a plurality of glue outlet nozzles, the glue outlet nozzles are arranged at one ends of the glue outlet pipelines close to the slide placing drawer, and the glue outlet ports of the glue outlet nozzles are arranged right opposite to the surface of the slide glass; the glue outlet nozzle is provided with a control assembly, the control assembly comprises an electromagnetic valve, a quantitative module and a control module, and the control module is respectively electrically connected with the electromagnetic valve and the quantitative module. The slide glass is fixedly placed through the slide placing drawer, and the mounting glue drips onto the surface of the corresponding cover glass on the slide glass from the glue outlet nozzle, so that quantitative glue sealing is realized, and the situations of waste and the like during manual glue squeezing are avoided.
Description
Technical Field
The utility model relates to a mounting is glued technical field, particularly, relates to a ration molding equipment.
Background
Fluorescence In Situ Hybridization (FISH) is based on the principle of complementary pairing of nucleic acid bases, DNA or RNA probes are labeled with haptens and are complementarily paired with denatured single-stranded nucleic acid sequences, the haptens are identified by antibodies with fluorophores for detection, or the probes are directly labeled with the fluorophores and combined with target sequences, and the distribution of the target sequences in cell nuclei, chromosomes or slice tissues is directly observed by a fluorescence microscope.
In the denaturation-annealing-renaturation process, a probe is required to be hybridized with a nucleic acid to be detected according to the base complementary pairing principle. Hybridization is the most critical step and the longest period of the FISH experiment, and any detail can influence the success rate of the experiment. In the hybridization process, in order to prevent evaporation of hybridization solution caused by long-time high-temperature incubation, a silicified cover glass is required to be added, and rubber glue is adopted for sealing glue treatment. The common rubber cement is tubular packaging, such as Marabu FixoGum FISH sealing adhesive, and has the following problems in use: the extrusion amount is difficult to control, and waste is caused by excessive extrusion of the sheet sealing glue; due to the problem of manipulation, bubbles are easily generated, or the periphery of the slide is not tightly sealed, so that the hybridization is not successful, and the slide reading is affected.
Therefore, a quantitative sealant sealing device is urgently needed to avoid the problem of difficult control of the extrusion amount of the sealing adhesive in the above experimental operation.
SUMMERY OF THE UTILITY MODEL
The utility model aims to solve current FISH experimental species, the problem of the difficult control of extrusion capacity is sealed to the hybridization process. The application provides a ration molding equipment, through putting the fixed slide glass of placing of piece drawer, the mounting is glued and is dripped the cover glass surface that corresponds on the slide glass from the play jiao zui to realize the ration and glue, appear extravagant the wait condition when avoiding manual crowded glue.
The utility model discloses a following technical scheme realizes:
a quantitative glue sealing device comprises a glue sealing box body, wherein the glue sealing box body is provided with a plurality of horizontally distributed sheet placing drawers, and a glue discharging assembly penetrates through the top of the glue sealing box body; the glue outlet assembly comprises a plurality of glue outlet pipelines and a plurality of glue outlet nozzles, the glue outlet nozzles are arranged at one ends of the glue outlet pipelines close to the slide placing drawer, and glue outlet ports of the glue outlet nozzles are arranged right opposite to the surface of the slide glass; the glue outlet nozzle is provided with a control assembly, the control assembly comprises an electromagnetic valve, a quantitative module and a control module, and the control module is respectively electrically connected with the electromagnetic valve and the quantitative module.
Preferably, the surface of the inner bottom of the slide placing drawer is provided with a plurality of limiting blocks, and the glass slide is clamped with the side wall surfaces of the limiting blocks.
Preferably, the inner bottom surface of the slide placing drawer is provided with a pair of concave parts, the concave parts are arranged between two adjacent limiting blocks, so that the surfaces of the concave parts are covered with the holding ends of the glass slides after the glass slides are clamped with the limiting blocks.
Preferably, go out the gluey pipeline and keep away from the one end of going out gluey mouth is configured with helical joint, helical joint wears to locate the top of film-making box, go out gluey pipeline bury underground in seal gluey box top.
Preferably, the screw joint is provided with a screw plug.
Preferably, the middle part of the glue outlet pipeline is communicated with a buffer storage tank, and the buffer storage tank is embedded at the top of the glue sealing box body.
Preferably, the control assembly further includes a numerical control panel and a power module, the numerical control panel is disposed on an outer surface of the sealant box body, the numerical control panel is electrically connected to the control module and the power module, and the power module is electrically connected to the electromagnetic valve, the quantitative module and the control module.
Preferably, the control module further comprises a timer and an alarm, the timer is electrically connected with the control module and the power module respectively, and the alarm is electrically connected with the control module and the power module respectively.
The technical scheme of the utility model following beneficial effect has:
(1) Through putting the fixed slide glass of placing of piece drawer, the mounting is glued and is dripped the cover glass surface that corresponds on the slide glass from the play jiao zui to realize the ration and glue, appear extravagant the wait condition when avoiding manual crowded to glue.
(2) When the device is used, the number and the configuration positions of the glue outlet pipelines and the glue outlet nozzles can be adjusted according to actual conditions so as to meet the requirement of sealing glue on a cover glass area of the surface of the glass slide with the probe in an experiment.
Drawings
In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings that are required to be used in the embodiments will be briefly described below, it should be understood that the following drawings only illustrate some embodiments of the present invention, and therefore should not be considered as limiting the scope, and for those skilled in the art, other related drawings can be obtained according to the drawings without inventive efforts.
FIG. 1 is a schematic view of a quantitative sealant sealing apparatus in example 1;
FIG. 2 is a schematic cross-sectional view of the quantitative sealant sealing apparatus in embodiment 1;
FIG. 3 is a partially enlarged schematic view of the portion A in FIG. 2;
FIG. 4 is a schematic view showing a structure of the sheet drawer according to embodiment 1;
FIG. 5 is a circuit diagram of the quantitative encapsulation apparatus in embodiment 1.
An icon: 1-glue sealing box body, 2-sheet placing drawer, 21-limiting block, 22-concave part, 31-glue outlet pipeline, 32-glue outlet nozzle, 33-spiral joint, 34-spiral plug, 35-buffer storage tank, 41-electromagnetic valve, 42-quantitative module, 43-control module, 44-numerical control panel, 45-power module, 46-timer and 47-alarm.
Detailed Description
In order to make the objects, technical solutions and advantages of the embodiments of the present invention clearer, the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are some, but not all, embodiments of the present invention. The components of the embodiments of the present invention generally described and illustrated in the figures herein may be arranged and designed in a wide variety of different configurations.
Thus, the following detailed description of the embodiments of the present invention, presented in the accompanying drawings, is not intended to limit the scope of the invention, as claimed, but is merely representative of selected embodiments of the invention. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative efforts belong to the protection scope of the present invention.
It should be noted that: like reference numbers and letters refer to like items in the following figures, and thus, once an item is defined in one figure, it need not be further defined or explained in subsequent figures.
Example 1
As shown in fig. 1 to 5, the present embodiment provides a quantitative sealant sealing device, which includes a sealant box 1, the sealant box 1 is configured with a plurality of horizontally distributed sheet placing drawers 2, and a sealant discharging assembly is disposed through the top of the sealant box 1; the glue outlet assembly comprises a plurality of glue outlet pipelines 31 and a plurality of glue outlet nozzles 32, the glue outlet nozzles 32 are arranged at one ends of the glue outlet pipelines 31 close to the slide placing drawer 2, and glue outlet ports of the glue outlet nozzles 32 are arranged opposite to the surfaces of the glass slides; the glue outlet 32 is provided with a control assembly, the control assembly comprises an electromagnetic valve 41, a quantitative module 42 and a control module 43, the control module 43 is electrically connected with the electromagnetic valve 41 and the quantitative module 42 respectively, and the electromagnetic valve 41 is used for controlling the opening and closing of the glue outlet. Through putting the slide glass of fixed placing of piece drawer 2, the mounting is glued from going out gluey mouth 32 drippage to the slide glass on the corresponding glass cover plate surface to realize the ration and glue, appear extravagant the circumstances such as when avoiding manual crowded glue.
In this embodiment, the control module 43 is a controller, and may be a single chip microcomputer (for example, 8051 series single chip microcomputers, STM32 series single chip microcomputers), an FPGA programmable controller, or the like; the quantitative module 42 comprises an infrared sensor, a PLC and the like, the infrared sensor is arranged at one end of the glue outlet pipeline 31 close to the glue outlet nozzle 32, an infrared lens of the infrared sensor is over against the inner cavity of the glue outlet pipeline 31, the flow volume of the sealing glue flowing through can be sensed and collected, and the PLC is used for calculating the flow volume; the controller sets a quantitative value, when the flow rate of the glue flowing through the infrared sensor in the glue outlet pipeline 31 reaches a set value, the quantitative module 42 transmits a signal to the controller, and the controller controls the electromagnetic valve 41 to be closed, namely, the glue outlet is stopped. Those skilled in the art can select other conventional quantitative devices for quantitative liquid discharge of the liquid discharge pipe according to the actual situation, and can also select to embed the devices in the control module 43 and the quantitative module 42 in the sealant box 1 or to arrange the devices on the inner side wall or the outer side wall of the sealant box 1 according to the actual situation.
In this embodiment, the surface of the inner bottom of the slide placing drawer 2 is provided with a plurality of limiting blocks 21, and the glass slides are clamped with the side wall surfaces of the limiting blocks 21; the inner bottom surface of the slide placing drawer 2 is provided with a pair of concave parts 22, and the concave parts 22 are arranged close to the space between two adjacent limiting blocks 21, so that the holding ends of the glass slides cover the surfaces of the concave parts 22 after the glass slides are clamped with the limiting blocks 21. A spiral joint 33 is arranged at one end of the glue outlet pipeline 31 far away from the glue outlet nozzle 32, the spiral joint 33 penetrates through the top of the sheet making box body, and the glue outlet pipeline 31 is embedded in the top of the glue sealing box body 1; the screw joint 33 is provided with a screw stopper 34.
In this embodiment, the middle portion of the glue outlet pipe 31 is communicated with the buffer storage tank 35, and the buffer storage tank 35 is embedded in the top of the glue sealing box 1. The buffer tank 35 is provided to avoid the problem of insufficient glue discharge or air bubbles.
In this embodiment, the control assembly further includes a numerical control panel 44 and a power module 45, the numerical control panel 44 is disposed on the outer surface of the sealant box 1, the numerical control panel 44 is electrically connected to the controller and the power module 45, and the power module 45 is electrically connected to the electromagnetic valve 41, the quantitative module 42, and the controller. The controller further includes a timer 46 and an alarm 47, the timer 46 being electrically connected to the controller and power module 45, respectively, and the alarm 47 being electrically connected to the controller and power module 45, respectively. The power module 45 is a power supply, and a common small-sized direct current power supply can be selected.
In this embodiment, when the device is used, a person skilled in the art can adjust the number and the arrangement position of the glue outlet pipes 31 and the glue outlet nozzles 32 according to actual conditions, so as to meet the requirement of performing glue sealing treatment on a cover glass region where a probe is added on the surface of a slide glass in an experiment.
The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention, and various modifications and changes may be made by those skilled in the art. Any modification, equivalent replacement, or improvement made within the spirit and principle of the present invention should be included in the protection scope of the present invention.
Claims (8)
1. The quantitative glue sealing device is characterized by comprising a glue sealing box body (1), wherein the glue sealing box body (1) is provided with a plurality of horizontally distributed sheet placing drawers (2), and a glue discharging assembly penetrates through the top of the glue sealing box body (1);
the glue outlet assembly comprises a plurality of glue outlet pipelines (31) and a plurality of glue outlet nozzles (32), the glue outlet nozzles (32) are arranged at one end of each glue outlet pipeline (31) close to the slide placing drawer (2), and the glue outlet of each glue outlet nozzle (32) is arranged right opposite to the surface of the glass slide;
go out jiao zui (32) and dispose control assembly, control assembly includes solenoid valve (41), ration module (42) and control module (43), control module (43) respectively with solenoid valve (41) with ration module (42) electricity is connected.
2. The quantitative sealant sealing device according to claim 1, wherein a plurality of limiting blocks (21) are disposed on the surface of the inner bottom of the sheet placing drawer (2), and the glass slide is clamped with the side wall surfaces of the limiting blocks (21).
3. The quantitative glue sealing device according to claim 2, characterized in that a pair of concave portions (22) are arranged on the inner bottom surface of the sheet placing drawer (2), and the concave portions (22) are arranged close to and between two adjacent limiting blocks (21), so that after the glass slide is clamped with the limiting blocks (21), the holding end of the glass slide covers the surface of the concave portions (22).
4. The quantitative sealant sealing device as claimed in claim 1, wherein a screw joint (33) is disposed at an end of the sealant outlet pipe (31) far away from the sealant outlet nozzle (32), the screw joint (33) penetrates through a top of the sealant box body (1), and the sealant outlet pipe (31) is embedded in the top of the sealant box body (1).
5. The quantitative sealant device as claimed in claim 4, characterized in that the screw joint (33) is provided with a screw stopper (34).
6. The quantitative sealant sealing device of claim 4, wherein a buffer storage tank (35) is connected to a middle portion of the sealant outlet pipe (31), and the buffer storage tank (35) is embedded in a top portion of the sealant box body (1).
7. The quantitative sealant device according to any one of claims 1 to 6, wherein the control assembly further comprises a numerical control panel (44) and a power module (45), the numerical control panel (44) is disposed on an outer surface of the sealant box body (1), the numerical control panel (44) is electrically connected to the control module (43) and the power module (45), respectively, and the power module (45) is electrically connected to the solenoid valve (41), the quantitative module (42) and the control module (43), respectively.
8. The quantitative sealant device as claimed in claim 7, wherein the control module (43) further comprises a timer (46) and an alarm (47), the timer (46) is electrically connected to the control module (43) and the power module (45), respectively, and the alarm (47) is electrically connected to the control module (43) and the power module (45), respectively.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202222984644.1U CN218860745U (en) | 2022-11-09 | 2022-11-09 | Quantitative glue sealing device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202222984644.1U CN218860745U (en) | 2022-11-09 | 2022-11-09 | Quantitative glue sealing device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN218860745U true CN218860745U (en) | 2023-04-14 |
Family
ID=87374725
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202222984644.1U Active CN218860745U (en) | 2022-11-09 | 2022-11-09 | Quantitative glue sealing device |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN218860745U (en) |
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2022
- 2022-11-09 CN CN202222984644.1U patent/CN218860745U/en active Active
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