CN218792630U - Anti-bending artificial blood vessel - Google Patents

Anti-bending artificial blood vessel Download PDF

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Publication number
CN218792630U
CN218792630U CN202220509395.8U CN202220509395U CN218792630U CN 218792630 U CN218792630 U CN 218792630U CN 202220509395 U CN202220509395 U CN 202220509395U CN 218792630 U CN218792630 U CN 218792630U
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blood vessel
artificial blood
synthetic polymer
bending
resistant
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李松
祝翊倩
陆亚明
孙彬彬
邢美毅
段晓博
王春蕾
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Shengna Technology Shanghai Co ltd
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Shengna Technology Shanghai Co ltd
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    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
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Abstract

The utility model discloses an anti-bending artificial blood vessel, which comprises an artificial blood vessel inner layer, a synthetic polymer anti-bending layer and an artificial blood vessel outer layer; the inner layer of the artificial blood vessel is a synthetic polymer tube body; the outer layer of the artificial blood vessel is a synthetic polymer fiber membrane; the appearance of the synthesized macromolecule bending-resistant folded ring is of a non-equidistant spiral structure; the synthetic polymer bending-resistant folded ring is wound on the outer wall of the inner layer of the artificial blood vessel, is arranged between the inner layer of the artificial blood vessel and the outer layer of the artificial blood vessel, and is covered and fixed by the inner layer of the artificial blood vessel and the outer layer of the artificial blood vessel. The utility model also discloses a preparation method of the artificial blood vessel. The utility model discloses, make artificial blood vessel can carry out 180 arbitrary bendings of complete ring and can not appear flat collapse, kink phenomenon, guarantee that whole artificial blood vessel all possesses good anti performance of buckling, can effectively improve artificial blood vessel's anti performance of buckling, effectively improve artificial blood vessel compliance simultaneously.

Description

Anti-bending artificial blood vessel
Technical Field
The utility model relates to the technical field of medical equipment, a bending-resistant artificial blood vessel is related to.
Background
According to epidemiological statistics, the incidence rate of chronic nephropathy in China is up to 10.8%, the number of patients is about 1.3 hundred million, and the number of end-stage nephropathy is about 300 ten thousand. Clinically, hemodialysis is one of the main treatment means for patients with end-stage renal disease. The establishment of a reasonable vascular access has great significance for the end-stage nephropathy patients to successfully receive dialysis treatment.
However, with the improvement of domestic living standard and medical technology, the life cycle of hemodialysis patients is prolonged, the autologous blood vessels are irreversibly damaged along with the increase of dialysis age and are limited by the quality and quantity of the autologous blood vessels, and artificial arteriovenous fistulation is an ideal treatment means for maintaining high-quality dialysis. However, the artificial blood vessel is bent or kinked along with the limb movement of the patient after being implanted into the human body, and if the artificial blood vessel lacks good mechanical support, the artificial blood vessel may generate blood coagulation to block the blood vessel, so that thrombus is formed, and the artificial blood vessel is forced to be subjected to thrombus removal or secondary operation, which directly influences the dialysis and the life quality of the patient after the operation.
At present, a lot of artificial blood vessels such as company products of Bard, nicast, gore and the like are clinically used in China, wherein Bard realizes bending and kinking resistance by winding a full-ring hard structure silk thread outside an expanded polytetrafluoroethylene tube, but the mechanical matching of the whole artificial blood vessel is obviously enhanced due to the hard high-density full-ring silk thread, so that the mechanical matching of the artificial blood vessel and the autologous blood vessel is greatly reduced, and the autologous blood vessel at an anastomotic stoma is torn and drawn by the artificial blood vessel, and the blood leakage phenomenon is caused. Only the middle 80mm of the Nicast artificial blood vessel product with the length of 400mm has a bending-resistant folding ring, so that only 80mm of blood vessel has a bending-resistant function, other parts without the bending ring can not realize good bending-resistant performance, and meanwhile, the bending-resistant part is shorter, so that the clinical application material-taking length is limited. Gore company adopts silica gel compact layer thickening artificial blood vessel body to promote mechanical properties and realize anti buckling, nevertheless because of the silica gel elastomer mechanical strength is lower, can not realize 180 arbitrary bendings, the thick clinical suture of not being convenient for of silica gel layer thickness simultaneously. In chinese patent document CN112472361B, the bohan poplar company uses a high temperature extrusion process at 300 ℃ or higher to prepare the bending-resistant corrugated ring, and the high temperature is not favorable for receiving the electrostatic spinning material, which can seriously affect the state of the nanofiber, and cause the inner layer of the nanofiber to be broken and deformed at high temperature, so that the processes of adding the first dense layer and the second dense layer are complicated, and are not favorable for realizing industrialization.
SUMMERY OF THE UTILITY MODEL
The to-be-solved technical problem of the utility model is, make artificial blood vessel can carry out 180 arbitrary bendings of complete ring and can not appear flat collapse, kink phenomenon, guarantee that whole artificial blood vessel all possesses good anti bending property, can effectively improve artificial blood vessel's anti bending property, effectively improve artificial blood vessel compliance simultaneously.
In order to solve the technical problem, the utility model provides an anti-bending artificial blood vessel tube, which comprises an artificial blood vessel inner layer 1, a synthetic polymer anti-bending folded ring 2 and an artificial blood vessel outer layer;
the inner layer 1 of the artificial blood vessel is a synthetic polymer tube body;
the outer layer of the artificial blood vessel is a synthetic polymer fiber membrane;
the appearance of the synthetic polymer bending-resistant folded ring 2 is a non-equidistant spiral structure;
the synthetic polymer bending-resistant folded ring 2 is wound on the outer wall of the artificial blood vessel inner layer 1, is arranged between the artificial blood vessel inner layer 1 and the artificial blood vessel outer layer, and is covered and fixed by the artificial blood vessel inner layer 1 and the artificial blood vessel outer layer.
Preferably, the distance between the synthetic polymer bending-resistant ring 2 is gradually increased from the middle part of the artificial blood vessel to the two ends of the artificial blood vessel along the central line of the artificial blood vessel.
Preferably, the length of the synthetic polymer bending-resistant folded ring 2 is consistent with the length of the central line of the artificial blood vessel;
the length of the synthetic polymer bending-resistant ring 2 is 400 mm-600 mm.
Preferably, the artificial blood vessel inner layer 1 is prepared by adopting a synthetic polymer material through an electrostatic spinning process;
the outer layer of the artificial blood vessel is prepared by adopting a synthetic polymer material through an electrostatic spinning process.
Preferably, the inner diameter of the artificial blood vessel inner layer 1 is 3 mm-6 mm, and the thickness of the tube wall is 0.3-1 mm.
Preferably, the thickness of the outer layer of the artificial blood vessel is 0.1 mm-0.5 mm.
Preferably, the synthetic polymer material comprises polyurethane, siloxane-terminated polycarbonate, nylon, polytetrafluoroethylene, polyvinyl alcohol, polylactic acid, polyethylene and polycaprolactone.
Preferably, the synthetic polymer material comprises polyurethane, siloxane-terminated polycarbonate, polyethylene terephthalate and perfluoroethylene propylene copolymer.
Preferably, the synthetic polymer bending-resistant folded ring 2 is formed by winding solid silk threads, and the diameter of the silk threads is 0.2 mm-0.4 mm;
the ring spacing of the synthetic polymer bending-resistant folded ring 2 is 1 mm-8 mm.
The utility model discloses an anti-bending artificial blood vessel, anti-bending book encircles and adopts non-equidistance helical structure, make artificial blood vessel can the complete ring carry out 180 arbitrary bendings and can not appear flat collapse, kink phenomenon, guarantee that whole root artificial blood vessel all possesses good anti performance of buckling, can effectively improve artificial blood vessel's anti performance of buckling, effectively improve artificial blood vessel compliance simultaneously, can effectively alleviate the autologous blood vessel that brings because of the design of high density complete ring torn by the tractive, the condition of blood leakage, the doctor can be in arbitrary interstellar intercepting, be convenient for satisfy clinical diversity length demand, can effectively prevent to take place to buckle or kink after artificial blood vessel implants the human body.
Drawings
In order to more clearly illustrate the technical solution of the present invention, the drawings required for the present invention are briefly introduced below, and it is obvious that the drawings in the following description are only some embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to these drawings without creative efforts.
Fig. 1 is a schematic structural view of an embodiment of the anti-bending artificial blood vessel of the present invention without an artificial blood vessel outer layer.
The reference numbers in the figures illustrate that:
1 is the inner layer of an artificial blood vessel; 2 synthesizing the macromolecule bending-resistant ring.
Detailed Description
The technical solutions of the present invention will be described clearly and completely with reference to the accompanying drawings, and it should be understood that the described embodiments are only some embodiments, but not all embodiments, of the present invention. Based on the embodiments of the present invention, all other embodiments obtained by a person of ordinary skill in the art without creative efforts belong to the protection scope of the present invention.
Example one
As shown in fig. 1, the bending-resistant artificial blood vessel comprises an artificial blood vessel inner layer 1, a synthetic polymer bending-resistant fold ring 2 and an artificial blood vessel outer layer;
the inner layer 1 of the artificial blood vessel is a synthetic polymer tube body;
the outer layer of the artificial blood vessel is a synthetic polymer fibrous membrane;
the appearance of the synthetic polymer bending-resistant folded ring 2 is a non-equidistant spiral structure;
the synthetic polymer bending-resistant folded ring 2 is wound on the outer wall of the artificial blood vessel inner layer 1, is arranged between the artificial blood vessel inner layer 1 and the artificial blood vessel outer layer, and is coated and fixed by the artificial blood vessel inner layer 1 and the artificial blood vessel outer layer.
The artificial blood vessel of the first embodiment has a three-layer structure, the inner layer is a synthetic polymer tube, the outer layer is a synthetic polymer fiber membrane, a synthetic polymer bending-resistant ring is arranged between the inner layer and the outer layer, the bending-resistant ring is fixed by coating the inner layer and the outer layer, and the synthetic polymer bending-resistant ring 2 has a non-equidistant spiral structure.
The artificial blood vessel of the first embodiment, bending-resistant corrugated rim adopts non-equidistance helical structure, make artificial blood vessel can the complete ring carry out 180 arbitrary bendings and can not appear flat collapse, kink phenomenon, guarantee that whole artificial blood vessel all possesses good anti buckling performance, can effectively improve artificial blood vessel's anti buckling performance, effectively improve artificial blood vessel compliance simultaneously, can effectively alleviate the autologous blood vessel that brings because of the design of high density complete ring and be torn by the tractive, the condition of blood leakage, the doctor can be intercepted at arbitrary interloop, be convenient for satisfy clinical diversity length demand, can effectively prevent to take place to buckle or kink after artificial blood vessel implants the human body.
Example two
Based on the artificial blood vessel of the first embodiment, the distance between the synthetic polymer bending-resistant rings 2 gradually increases from the middle part of the artificial blood vessel to the two ends of the artificial blood vessel along the central line of the artificial blood vessel.
Preferably, the length of the synthetic polymer bending-resistant fold 2 is consistent with the length of the central line of the artificial blood vessel.
Preferably, the length of the synthetic polymer bending-resistant fold ring 2 is 400 mm-600 mm.
In the artificial blood vessel of the second embodiment, the synthetic polymer bending-resistant folded rings 2 are of a gradually-changed inter-annular-space structure with the bending-resistant performance and spirally wound, and the inter-annular-space of the synthetic polymer bending-resistant folded rings 2 is gradually increased from the middle part of the artificial blood vessel to the two ends of the artificial blood vessel, and the inter-annular-space of the synthetic polymer bending-resistant folded rings 2 in the middle part of the artificial blood vessel is smaller, so that the inter-annular-space is increased like the extension of the two ends, the mechanics of the artificial blood vessel can be effectively reduced, and the compliance of the artificial blood vessel is improved.
EXAMPLE III
Based on the artificial blood vessel of the first embodiment, the inner layer 1 of the artificial blood vessel is prepared by adopting a synthetic polymer material through an electrostatic spinning process;
the outer layer of the artificial blood vessel is prepared by adopting a synthetic polymer material through an electrostatic spinning process.
Preferably, the inner diameter of the artificial blood vessel inner layer 1 is 3 mm-6 mm, and the thickness of the tube wall is 0.3-1 mm.
Preferably, the thickness of the outer layer of the artificial blood vessel is 0.1 mm-0.5 mm.
Preferably, the synthetic polymer material includes, but is not limited to, polyurethane (aromatic, aliphatic, etc.), siloxane-terminated polycarbonate (aliphatic, aromatic), nylon, polytetrafluoroethylene, polyvinyl alcohol, polylactic acid, polyethylene, polycaprolactone.
Preferably, the synthetic polymer material includes polyurethane (aromatic, aliphatic, etc.), siloxane-terminated polycarbonate (aliphatic, aromatic), polyethylene terephthalate (PET), and perfluoroethylene propylene copolymer (FEP).
In the artificial blood vessel of the third embodiment, the artificial blood vessel inner layer 1 and the artificial blood vessel outer layer are both prepared by adopting an electrostatic spinning mode of synthetic polymer materials.
Example four
Based on the artificial blood vessel of the first embodiment, the synthetic polymer bending-resistant folded ring 2 is formed by winding solid silk threads, and the diameter of the silk threads is 0.2 mm-0.4 mm;
the ring spacing (thread pitch) of the synthetic polymer bending-resistant folded ring 2 is 1 mm-8 mm.
The above are merely preferred embodiments of the present application and are not intended to limit the present application. Various modifications and changes may occur to those skilled in the art. Any modification, equivalent replacement, improvement and the like made within the spirit and principle of the present application shall be included in the protection scope of the present application.

Claims (7)

1. An anti-bending artificial blood vessel is characterized by comprising an artificial blood vessel inner layer (1), a synthetic polymer anti-bending folding ring (2) and an artificial blood vessel outer layer;
the artificial blood vessel inner layer (1) is a synthetic polymer tube body;
the outer layer of the artificial blood vessel is a synthetic polymer fibrous membrane;
the appearance of the synthetic polymer bending-resistant folded ring (2) is a non-equidistant spiral structure;
the synthetic polymer bending-resistant folded ring (2) is wound on the outer wall of the artificial blood vessel inner layer (1), is arranged between the artificial blood vessel inner layer (1) and the artificial blood vessel outer layer, and is coated and fixed by the artificial blood vessel inner layer (1) and the artificial blood vessel outer layer.
2. The kink-resistant artificial blood vessel according to claim 1,
the space between the synthetic polymer bending-resistant folding rings (2) is gradually increased from the middle part of the artificial blood vessel to the two ends of the artificial blood vessel along the central line of the artificial blood vessel.
3. The kink-resistant artificial blood vessel according to claim 1,
the length of the synthetic polymer bending-resistant folded ring (2) is consistent with the length of the central line of the artificial blood vessel;
the length of the synthetic polymer bending-resistant folding ring (2) is 400-600 mm.
4. The kink-resistant artificial blood vessel according to claim 1,
the artificial blood vessel inner layer (1) is prepared from a synthetic high polymer material through an electrostatic spinning process;
the outer layer of the artificial blood vessel is prepared by adopting a synthetic polymer material through an electrostatic spinning process.
5. The kink-resistant artificial blood vessel according to claim 1,
the inner diameter of the artificial blood vessel inner layer (1) is 3 mm-6 mm, and the thickness of the tube wall is 0.3-1 mm.
6. The kink-resistant artificial blood vessel according to claim 1,
the thickness of the outer layer of the artificial blood vessel is 0.1 mm-0.5 mm.
7. The kink-resistant artificial blood vessel according to claim 1,
the synthetic polymer bending-resistant folding ring (2) is formed by winding solid silk threads, and the diameter of the silk threads is 0.2-0.4 mm;
the space between the synthetic polymer bending-resistant folded rings (2) is 1 mm-8 mm.
CN202220509395.8U 2022-03-10 2022-03-10 Anti-bending artificial blood vessel Active CN218792630U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202220509395.8U CN218792630U (en) 2022-03-10 2022-03-10 Anti-bending artificial blood vessel

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202220509395.8U CN218792630U (en) 2022-03-10 2022-03-10 Anti-bending artificial blood vessel

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CN218792630U true CN218792630U (en) 2023-04-07

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116549171A (en) * 2023-07-12 2023-08-08 苏州美创医疗科技有限公司 Artificial blood vessel

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116549171A (en) * 2023-07-12 2023-08-08 苏州美创医疗科技有限公司 Artificial blood vessel

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