CN109498957A - A kind of novel microtubular - Google Patents

A kind of novel microtubular Download PDF

Info

Publication number
CN109498957A
CN109498957A CN201910025134.1A CN201910025134A CN109498957A CN 109498957 A CN109498957 A CN 109498957A CN 201910025134 A CN201910025134 A CN 201910025134A CN 109498957 A CN109498957 A CN 109498957A
Authority
CN
China
Prior art keywords
layer
novel
braiding
microtubular
distal end
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201910025134.1A
Other languages
Chinese (zh)
Inventor
张钲
王平
肖建平
向东东
于伟
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shenzhen Industrial Co Ltd Poly Industry
Original Assignee
Shenzhen Industrial Co Ltd Poly Industry
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shenzhen Industrial Co Ltd Poly Industry filed Critical Shenzhen Industrial Co Ltd Poly Industry
Publication of CN109498957A publication Critical patent/CN109498957A/en
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/0043Catheters; Hollow probes characterised by structural features
    • A61M25/0045Catheters; Hollow probes characterised by structural features multi-layered, e.g. coated
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/0043Catheters; Hollow probes characterised by structural features
    • A61M25/005Catheters; Hollow probes characterised by structural features with embedded materials for reinforcement, e.g. wires, coils, braids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/0043Catheters; Hollow probes characterised by structural features
    • A61M25/0054Catheters; Hollow probes characterised by structural features with regions for increasing flexibility
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/0067Catheters; Hollow probes characterised by the distal end, e.g. tips
    • A61M25/0068Static characteristics of the catheter tip, e.g. shape, atraumatic tip, curved tip or tip structure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M2025/0008Catheters; Hollow probes having visible markings on its surface, i.e. visible to the naked eye, for any purpose, e.g. insertion depth markers, rotational markers or identification of type
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/0043Catheters; Hollow probes characterised by structural features
    • A61M2025/0063Catheters; Hollow probes characterised by structural features having means, e.g. stylets, mandrils, rods or wires to reinforce or adjust temporarily the stiffness, column strength or pushability of catheters which are already inserted into the human body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/02General characteristics of the apparatus characterised by a particular materials
    • A61M2205/0238General characteristics of the apparatus characterised by a particular materials the material being a coating or protective layer
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/32General characteristics of the apparatus with radio-opaque indicia

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Materials For Medical Uses (AREA)

Abstract

The invention discloses a kind of novel microtubulars, for tubular structure, including head end, pipe shaft, diffusion-induced stress pipe and the needle stand set gradually from distal end to proximal end, in which: doped with developability material in the head end, developing ring is equipped between the head end and the pipe shaft;The pipe shaft successively includes jacket layer, braiding enhancement layer, braiding layer and liner layer from outside to inside;And the pipe shaft proximal end and the needle stand are fixedly connected, the pipe shaft proximal end and the needle stand junction be arranged with the diffusion-induced stress pipe.Novel microtubular of the invention has very strong push performance, buckle resistance energy and tracking performance, conduit is gradually hardened from distal end to proximal end simultaneously, it can guarantee the flexibility and shape retention of distal end in this way, it is ensured that microtubular accurately reaches disease in surgical procedure in surgical procedure and becomes position and across tortuous lesion vessels.

Description

A kind of novel microtubular
Technical field
The present invention relates to a kind of microtubular more particularly to a kind of novel microtubulars.
Background technique
With the development of the social economy, deep variation, especially aging of population and city has occurred in national life mode The acceleration of town process, Chinese cardiovascular risk factors fashion trend is obvious, and the number of the infected for resulting in cardiovascular disease continues Increase.China probably has 2,200,000 with the patient of chronic total occlusion of coronary artery at present.
Clinically, when carrying out Minimally Interventional Therapy for the blood vessel of Chronic total occlusion or vascular dissection, in order to Improve the success rate of seal wire passed through, it usually needs microtubular and seal wire are used cooperatively, and microtubular is seal wire small first It is intravascular that additional support force is provided, and the two alternately moves ahead, and substantially increases the ability that seal wire passes through Occlusion.
After lesion locations are passed through in seal wire completion, it is also necessary to confirm that seal wire is in the very intracavitary next step that can carry out of blood vessel and controls Treat operation, such as the technological means such as balloon expandable, stenter to implant.Pass through imaging evaluation seal wire to blood vessel distal injection contrast agent Whether the true chamber of blood vessel is in.
In the course of surgery, it needs microtubular being pushed to lesion locations from vitro, this requires microtubulars to have very by force Push performance, buckle resistance energy and tracking performance etc., it is ensured that microtubular accurately reaches disease in surgical procedure and becomes position simultaneously Across lesion vessels, passes through and withdraw from without injuring healthy blood vessel, while convenient for seal wire.
Existing microtubular, it is small generally cannot all to meet pipe size simultaneously, but meet push performance, buckle resistance energy and Tracking performance is excellent, increases seal wire in this way and passes through the difficulty of Occlusion, while increasing the operation requirement to doctor, extends Conduit increases the physical effects of patient in the internal time of patient.
CN 107376101A describes a kind of microtubular for Transcaheter cloure TACE, the microtubular It include: tube socket, diffusion-induced stress pipe, pipe shaft and head end;Diffusion-induced stress pipe sleeve is covered in the outside of tube socket and pipe shaft junction, and is passed through The mode of back-off is fixed together with tube socket;Pipe shaft includes liner layer, enhancement layer and jacket layer;Enhancement layer includes braiding section, takes Section and spiral section are connect, wherein braiding section, close to tube socket, spiral section leans near head end, lap segment is located between braiding section and spiral section; The structure of helical spring is made of single taenidium for spiral section, and the microtubular head end of patent statement has good submissive Property, while head end has good shape retentivity, still, pushability performance is poor, because of one layer of braiding that proximal end only has Layer is reinforced, if it is desired to the wall thickness of conduit must be increased by improving push performance, will increase the size of conduit in this way, increases pipe size It will increase the difficulty by tortuous blood vessel, while increasing the risk and difficulty of operation.
US 7507229B2 describes a kind of for protruding into the multi-layer duct of the depths of human body, including liner layer, braiding layer And oversheath.Conduit is provided across height flexibility needed for vascular system and high intensity.External sheath layer is gradually hardened by 7 kinds Polymer material composition, the count of middle braid layer only has one-shot change, can not achieve the hardness of microtubular from distal end The process being gradually hardened to proximal end.
To sum up, the generally existing following problems of existing microtubular: microtubular is difficult the size having had both and good physical Energy;Microtubular cannot be guaranteed gradually to be hardened from conduit pipe shaft is distal-to-proximal;Flexibility is good, but push performance is bad, is easy It gives a discount;Head end shape retentivity is bad, can not be successfully into vascular bifurcation position.
Summary of the invention
The present invention is to solve above-mentioned technical problem present in existing microtubular, provides a kind of existing good size, and have Good physical property, while head end has the novel microtubular of good shape retentivity again.
To achieve the above object, the invention adopts the following technical scheme:
Provide a kind of novel microtubular, be tubular structure, including set gradually from distal end to proximal end head end, pipe shaft, Diffusion-induced stress pipe and needle stand, in which:
Doped with developability material in the head end, developing ring is equipped between the head end and the pipe shaft;
The pipe shaft successively includes jacket layer, braiding enhancement layer, braiding layer and liner layer from outside to inside;And
The proximal end of the pipe shaft is fixedly connected with the needle stand, and the pipe shaft proximal end and the junction of the needle stand are arranged with The diffusion-induced stress pipe.
Further, the outer diameter of the head end becomes larger from distal end to proximal end.
Further, the material of the head end is soft polyamide or flexibel polyurethane.
Further, the developability material is in tungsten powder or barium sulfate or bismuth oxide or bismuth subcarbonate or artificial schellite One or more of combinations.
Further, the proximal face joint welding of the head end is in braiding layer, and the braiding layer of the pipe shaft distal end The pipe shaft is stretched out with liner layer.
Further, the developing ring is embedded in the head end, and the developing ring coats the braiding layer completely Distal end end face.
Further, the material of the developing ring is platinumiridio or gold or platinum.
Further, the liner layer with a thickness of 0.008-0.02mm.
Further, the material of the liner layer is high density polyethylene (HDPE) or polytetrafluoroethylene (PTFE).
Further, the internal diameter of the liner layer becomes larger from distal end to proximal end, and the internal diameter of the liner layer distal end is 0.41-0.45mm, the internal diameter of the liner layer proximal end are 0.48-0.53mm.
Further, the braiding layer is woven by stainless steel braided wires or NiTi braided wires mariages, the braided wires For circle silk or flat filament or elliptical filaments.
Further, the braiding line number of the braiding layer is 16-32 strands, and the count PPI of the braiding layer is from distally It is gradually become smaller to proximal end, the count PPI of the braiding layer distal end is 220-280, the count of the braiding layer proximal end PPI is 50-100.
Further, the braiding enhancement layer is set to the proximal end of the pipe shaft, and the length of the braiding enhancement layer is 800- 1100mm。
Further, the braiding enhancement layer is woven by stainless steel braided wires or NiTi braided wires mariages, the volume The braiding line number for knitting enhancement layer is 20-36 strands, and being horizontally disposed in the braiding enhancement layer has several braiding reinforced wires 10.
Further, the proximal end face of the diffusion-induced stress pipe is fixedly connected by buckling with the distal face of the needle stand.
Further, the hardness of the jacket layer becomes larger from distal end to proximal end, the variation of the hardness of the jacket layer Range is 30-71D.
Further, the jacket layer is made of the different polyamide of a variety of hardness, polyurethane and polyolefine material;
Further, the outer diameter of the jacket layer becomes larger from distal end to proximal end, and the outer diameter of the jacket layer distal end is 0.05-0.066mm, the internal diameter of 4 proximal end of jacket layer are 0.81-0.92mm.
Further, hydrophilic coating is coated on the outer surface of the jacket layer.
The present invention by adopting the above technical scheme, compared with prior art, has the following technical effect that
Novel microtubular of the invention, have very strong push performance, buckle resistance energy and tracking performance, while conduit from It is distal-to-proximal to be gradually hardened, it can guarantee the flexibility and shape retention of distal end, it is ensured that microtubular is accurate in surgical procedure It reaches patient's diseased region and passes through tortuous lesion vessels.
Detailed description of the invention
Fig. 1 is the overall structure diagram of novel microtubular;
Fig. 2 is the braiding structure schematic diagram of novel microtubular;
Fig. 3 is novel microtubular pipe shaft and head end the schematic diagram of the section structure;
Fig. 4 is the braiding layer braiding structure schematic diagram of novel microtubular;
Fig. 5 is the sectional view of Section A-A in novel microtubular;
Fig. 6 is the braiding structure schematic diagram of braiding layer in novel microtubular;
Fig. 7 is the braiding structure schematic diagram that enhancement layer is woven in novel microtubular;
Fig. 8 is the sectional view of section B-B in novel microtubular;
Fig. 9 is the structural schematic diagram of jacket layer in novel microtubular;
Figure 10 is the structural schematic diagram of head end in novel microtubular
Figure 11 is the status diagram that novel microtubular enters blood vessel;
Wherein, each appended drawing reference are as follows:
1- head end, 2- pipe shaft, 3- needle stand, 4- jacket layer, 5- liner layer, 6- braiding layer, 7- weave enhancement layer, and 8- diffusion is answered Solenoid, 9- developing ring, 10- weave reinforced wire, 11 control towers protrusion, 12- control tower groove.
Specific embodiment
The present invention is described in more detail below by specific embodiment, for a better understanding of the present invention, But following embodiments are not intended to limit the scope of the invention.
As shown in figs. 1-11, be tubular structure the embodiment of the invention provides a kind of novel microtubular, including from distal end to Head end 1, pipe shaft 2, diffusion-induced stress pipe 8 and the needle stand 3 that proximal end is set gradually, in which: doped with developability material in head end 1, Developing ring 9 is equipped between head end 1 and pipe shaft 2;Pipe shaft 2 successively includes jacket layer 4, braiding enhancement layer 7, braiding layer 6 from outside to inside And liner layer 5;And the proximal end of pipe shaft 2 is fixedly connected with needle stand 3, the junction of 2 proximal end of pipe shaft and needle stand 3 is arranged with diffusion Stress tube 8.
The one side of the present embodiment, such as Fig. 1-3, shown in 9-11, the outer diameter of head end 1 becomes larger from distal end to proximal end, head End 1 uses airflow design, and it is smooth to guarantee that the head end of microtubular protrudes into human vas.
The one side of the present embodiment, the material of head end 1 are soft polyamide or flexibel polyurethane, and preferably polyether block is poly- Amide, polyether-block-polyamide have the performance of thermoplastic elastomer (TPE), polyether-block-polyamide due to its unique chemical structure For most light engineering thermoplastic elastomer, there is no the loss of mechanical performance under repeated deformation, and antifatigue, while polyethers is embedding Section polyamide is to guarantee that microtubular keeps size constancy, polyethers under different environmental conditions with accurate dimensional stability The good rebound of block polyamide and elasticity are restored, when microtubular is extracted out from human vas, it is ensured that microtubular is indeformable.
The one side of the present embodiment, such as Fig. 1-3, shown in 9-11, developability material is tungsten powder or barium sulfate or three oxidations two Bismuth or one or more of bismuth subcarbonate or artificial schellite, head end add simultaneously using soft polyether-block-polyamide material as base-material Enter that the extruding pipe that the auxiliary material of development is formed is logical, by welding procedure by head end with pipe shaft being combined together tightly.
The one side of the present embodiment, as shown in Figure 10, the proximal face joint welding of head end 1 is in braiding layer 6, and pipe shaft 2 is remote The braiding layer 6 and liner layer 5 at end stretch out pipe shaft 2, and the proximal face of head end 1 is equipped with protrusion 11 of setting up the stage, the distal end of pipe shaft 2 be equipped with by The groove 12 of setting up the stage that the upper surface of braiding layer 6 and 4 side end face of jacket layer are constituted, control tower protrusion 11 and 12 company of matching of control tower groove It connects, control tower protrusion 11 passes through welded connecting with control tower groove 12.
The one side of the present embodiment, such as Fig. 1-2, shown in 10-11, developing ring 9 is embedded in head end 1, and developing ring 9 is complete The distal end end face of braiding layer 6 is coated, one end of developing ring 9 is located at the junction of control tower protrusion 11 with control tower groove 12, developing ring 9 By braiding layer 6 tightly be strapped in internal layer, while providing the effect of development, then the extruded tube sleeve of the tube head 1 with developability Onto developing ring 9, the inside is wrapped in by welding, the dual development effect of head end may be implemented in this way, provided for patient One good development effect.
The one side of the present embodiment, such as Fig. 3, shown in 5,8,10, liner layer 5 with a thickness of 0.008-0.02mm, guaranteeing While 5 mechanical strength of liner layer, the thickness control of liner layer 5 is ensured that microtubular protrudes into people within 0.008-0.02mm Body blood vessel it is smooth, the mechanical strength of liner layer 5 will not be enhanced and sacrifice the integral thickness of microtubular.
The one side of the present embodiment, the material of developing ring 9 are platinumiridio or gold or platinum, platinumiridio, gold and Platinum develops clearly under X-ray, and medical personnel can be helped to position the position of microtubular in the blood vessel.
The one side of the present embodiment, the material of liner layer 5 are high density polyethylene (HDPE) or polytetrafluoroethylene (PTFE), highdensity poly- second Alkene and the equal part packet postal small volume of highdensity polytetrafluoroethylene (PTFE), the preferable feature of mechanical strength, liner layer select high density poly- While ethylene and high density polytetrafluoroethylene (PTFE) improve the mechanical strength of microtubular entirety, guarantee the diameter of microtubular it is smaller with Just microtubular is smooth enters human vas.
The one side of the present embodiment, such as Fig. 3, shown in 5,8,10, the internal diameter of liner layer 5 becomes larger from distal end to proximal end, The internal diameter of 5 distal end of liner layer is 0.41-0.45mm, and the internal diameter of 5 proximal end of liner layer is 0.48-0.53mm, and liner layer 5 can be to lead Silk, which provides, stablizes support.
The one side of the present embodiment, such as Fig. 2-6, shown in 10, braiding layer 6 is by stainless steel braided wires or NiTi braided wires mariages It weaves, braided wires are circle silk or flat filament or elliptical filaments, and the flexibility of microtubular can be enhanced using mariages braiding and prevent beating Folding ability.
The one side of the present embodiment, such as Fig. 2-6, shown in 10, the braiding line number of braiding layer 6 is 16-32 strands, braiding layer 6 Count PPI gradually becomes smaller from distal end to proximal end, and the count PPI of 6 distal end of braiding layer is 220-280,6 proximal end of braiding layer Count PPI be 50-100, in addition gradual change when the firmness change of conduit is woven using mariages, microtubular can be enhanced Flexibility and anti-discounting ability.
The one side of the present embodiment, as shown in Fig. 2-3,7-8,11, braiding enhancement layer 7 is set to the proximal end of pipe shaft 2, and braiding adds The length of strong layer 7 is 800-1100mm, and braiding enhancement layer 7 is not arranged in reason in braiding layer 6 comprehensively and is: due to microtubular Head end be introduced into human vas, therefore need preferable submissive performance, and part can be reduced to a certain extent by weaving enhancement layer 7 The flexibility of conduit is difficult to enter human vas, braiding enhancement layer 7 to the proximal end for being arranged in pipe shaft 2 to avoid the occurrence of microtubular.
The one side of the present embodiment, as shown in Fig. 2-3,7-8,11, braiding enhancement layer 7 is compiled by stainless steel braided wires or NiTi It knits a mariages to weave, the braiding line number of braiding enhancement layer 7 is 20-36 strands, and weaving to be horizontally disposed in enhancement layer 7 has several volumes Reinforced wire 10 is knitted, the push performance and twisting property of pipe shaft 2 can be enhanced by increasing braiding enhancement layer 7, while microtubular possesses Lesser size improves the passability of blood vessel, and especially when the collateral position tortuous in height occurs for lesion, the micro- of this design is led The advantage of pipe clinically is fairly obvious.
The one side of the present embodiment, as shown in Figure 1, left side of the right side of diffusion-induced stress pipe 8 by buckle and needle stand 3 It is fixedly connected, 2 proximal connecting end of microtubular pipe shaft is expanded into horn mouth, then inserted with the PC material of hard transparent by needle stand 3 Enter needle stand 3, then connect it with pipe shaft 2 with UV uv-curable glue, goes diffusion-induced stress pipe 8 with soft elastomer TPE material, Diffusion-induced stress pipe 8 is connect by back-off with needle stand 3.
The one side of the present embodiment, as shown in figure 9, the hardness of jacket layer 4 becomes larger from distal end to proximal end, jacket layer 4 The variation range of hardness is 30-71D, the gradual change when firmness change of conduit, can promoted it is micro- lead anti-discounting ability while Have both certain flexibility.
The one side of the present embodiment, as shown in figure 9, jacket layer 4 is by the different polyamide of a variety of hardness, polyurethane and gathers Olefin material is constituted, and in these three high molecular materials of polyamide, polyurethane and polyolefin, the hardness of polyamide is minimum, and The hardness highest of polyolefin, by unlike material, its own hardness performance realizes the hardness gradient effect of jacket layer 4.
The one side of the present embodiment, as shown in figure 9, the outer diameter of jacket layer 4 becomes larger from distal end to proximal end, jacket layer 4 The outer diameter of distal end is 0.05-0.066mm, and the internal diameter of 4 proximal end of jacket layer is 0.81-0.92mm, and jacket layer 4 sets for streamlined structure Meter, it is smooth into human vas that such structure design is conducive to microtubular.
The one side of the present embodiment is coated with hydrophilic coating on the outer surface of jacket layer 4, significantly reduces entire micro- lead The coefficient of friction of pipe further enhances his passage capacity.
The present invention is difficult the size having had both and good physical property for existing microtubular, it cannot be guaranteed that from catheter tube Body is distal-to-proximal to be gradually hardened, flexibility is good, but it is bad to push performance, be easy to give a discount and head end shape retentivity not Good, the problems such as can not be successfully into vascular bifurcation position, the present invention has very strong push performance, buckle resistance energy and tracing property Can, while conduit is gradually hardened from distal end to proximal end, can guarantee the flexibility and shape retention of distal end in this way, it is ensured that micro- to lead Pipe accurately reaches disease in surgical procedure and becomes position and across tortuous lesion vessels.
The specific embodiment of microtubular of the present invention is described in detail above, but it is merely an example, the present invention It is not restricted to particular embodiments described above.To those skilled in the art, what any couple of present invention carried out is equal Modifications and substitutions are also all among scope of the invention.Therefore, made impartial without departing from the spirit and scope of the invention Transformation and modification, all should be contained within the scope of the invention.

Claims (19)

  1. Be tubular structure 1. a kind of novel microtubular, which is characterized in that including set gradually from distal end to proximal end head end (1), Pipe shaft (2), diffusion-induced stress pipe (8) and needle stand (3), in which:
    Doped with developability material in the head end (1), developing ring (9) are equipped between the head end (1) and the pipe shaft (2);
    The pipe shaft (2) successively includes jacket layer (4), braiding enhancement layer (7), braiding layer (6) and liner layer from outside to inside (5);And
    The proximal end of the pipe shaft (2) is fixedly connected with the needle stand (3), the connection of pipe shaft (2) proximal end and the needle stand (3) Place is arranged with the diffusion-induced stress pipe (8).
  2. 2. novel microtubular according to claim 1, which is characterized in that the outer diameter of the head end (1) is from distal end to proximal end It becomes larger.
  3. 3. novel microtubular according to claim 2, which is characterized in that the material of the head end (1) is soft polyamide Or flexibel polyurethane.
  4. 4. novel microtubular according to claim 1, which is characterized in that the developability material be tungsten powder or barium sulfate or The combination of one or more of bismuth oxide or bismuth subcarbonate or artificial schellite.
  5. 5. novel microtubular according to claim 1, which is characterized in that the proximal face joint welding of the head end (1) is being compiled In tissue layer (6), and the braiding layer (6) of the pipe shaft (2) distal end and liner layer (5) stretch out the pipe shaft (2).
  6. 6. novel microtubular according to claim 1, which is characterized in that the developing ring (9) is embedded at the head end (1) It is interior, and the developing ring (9) coats the distal end end face of the braiding layer (6) completely.
  7. 7. novel microtubular according to claim 1, which is characterized in that the material of the developing ring (9) is platinumiridio Or gold or platinum.
  8. 8. novel microtubular according to claim 1, which is characterized in that the liner layer (5) with a thickness of 0.008- 0.02mm。
  9. 9. novel microtubular according to claim 8, which is characterized in that the material of the liner layer (5) is poly- for high density Ethylene or polytetrafluoroethylene (PTFE).
  10. 10. novel microtubular according to claim 1, which is characterized in that the internal diameter of the liner layer (5) is from distal end to close End becomes larger, and the internal diameter of liner layer (5) distal end is 0.41-0.45mm, and the internal diameter of liner layer (5) proximal end is 0.48-0.53mm。
  11. 11. novel microtubular according to claim 1, which is characterized in that the braiding layer (6) by stainless steel braided wires or NiTi braided wires mariages weaves, and the braided wires are circle silk or flat filament or elliptical filaments.
  12. 12. novel microtubular according to claim 1, which is characterized in that the braiding line number of the braiding layer (6) is 16- 32 strands, the count PPI of the braiding layer (6) gradually becomes smaller from distal end to proximal end, and the braiding of braiding layer (6) distal end is close Degree PPI is 220-280, and the count PPI of braiding layer (6) proximal end is 50-100.
  13. 13. novel microtubular according to claim 1, which is characterized in that the braiding enhancement layer (7) is set to the pipe shaft (2) proximal end, the length of braiding enhancement layer (7) are 800-1100mm.
  14. 14. novel microtubular according to claim 1, which is characterized in that the braiding enhancement layer (7) is woven by stainless steel Silk or NiTi braided wires mariages weave, and the braiding line number of braiding enhancement layer (7) is 20-36 strands, and the braiding is reinforced Being horizontally disposed in layer (7) has several braiding reinforced wires (10).
  15. 15. novel microtubular according to claim 1, which is characterized in that the proximal end face of the diffusion-induced stress pipe (8) passes through Buckle is fixedly connected with the distal face of the needle stand (3).
  16. 16. novel microtubular according to claim 1, which is characterized in that the hardness of the jacket layer (4) is from distal end to close End becomes larger, and the variation range of the hardness of the jacket layer (4) is 30-71D.
  17. 17. novel microtubular according to claim 16, which is characterized in that the jacket layer (4) is different by a variety of hardness Polyamide, polyurethane and polyolefine material constitute.
  18. 18. novel microtubular according to claim 1, which is characterized in that the outer diameter of the jacket layer (4) is from distal end to close End becomes larger, and the outer diameter of jacket layer (4) distal end is 0.05-0.066mm, and the internal diameter of jacket layer (4) proximal end is 0.81-0.92mm。
  19. 19. novel microtubular according to claim 1, which is characterized in that be coated on the outer surface of the jacket layer (4) Hydrophilic coating.
CN201910025134.1A 2018-12-19 2019-01-11 A kind of novel microtubular Pending CN109498957A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN201811556875 2018-12-19
CN2018115568754 2018-12-19

Publications (1)

Publication Number Publication Date
CN109498957A true CN109498957A (en) 2019-03-22

Family

ID=65757680

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201910025134.1A Pending CN109498957A (en) 2018-12-19 2019-01-11 A kind of novel microtubular

Country Status (3)

Country Link
JP (1) JP2022515796A (en)
CN (1) CN109498957A (en)
WO (1) WO2020124551A1 (en)

Cited By (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109999316A (en) * 2019-04-29 2019-07-12 南通伊诺精密塑胶导管有限公司 A kind of blood vessel microtubular with developing mark function
CN110537956A (en) * 2019-10-09 2019-12-06 上海加奇生物科技苏州有限公司 Catheter special for pumping thrombus at far end of cerebral vessel
CN110947077A (en) * 2019-12-02 2020-04-03 心凯诺医疗科技(上海)有限公司 High-flexibility distal access guiding catheter and preparation method thereof
WO2020124551A1 (en) * 2018-12-19 2020-06-25 深圳市业聚实业有限公司 Novel microcatheter
CN111467650A (en) * 2020-05-27 2020-07-31 深圳北芯生命科技有限公司 Micro-catheter
CN112402060A (en) * 2020-11-02 2021-02-26 金仕生物科技(常熟)有限公司 Delivery system of intervention valve
CN112401973A (en) * 2020-11-19 2021-02-26 上海腾复医疗科技有限公司 Multifunctional sheath tube
CN112472955A (en) * 2020-12-15 2021-03-12 上海融脉医疗科技有限公司 Multi-segment hardness interventional catheter and weaving method thereof
CN112472953A (en) * 2020-12-03 2021-03-12 广东博迈医疗器械有限公司 Braided catheter with reinforcing ribs
CN113181506A (en) * 2021-04-23 2021-07-30 谱高医疗科技(南京)有限公司 Micro catheter with weaving and spring winding composite structure
CN113198085A (en) * 2021-05-11 2021-08-03 深圳麦普奇医疗科技有限公司 Conveniently-implanted transradial coronary angiography catheter
CN113855992A (en) * 2020-06-30 2021-12-31 微创神通医疗科技(上海)有限公司 A catheter
CN114191685A (en) * 2021-10-19 2022-03-18 深圳北芯医疗科技有限公司 Catheter sheath
CN114699623A (en) * 2022-04-07 2022-07-05 深圳市凯思特医疗科技股份有限公司 Angiography catheter and angiography device
CN114832203A (en) * 2020-05-27 2022-08-02 深圳北芯生命科技股份有限公司 Microcatheter with tapered tip
CN114904121A (en) * 2022-04-24 2022-08-16 广州易介医疗科技有限公司 Medical leading-in tube, guiding catheter device thereof and radial artery access catheter system
CN115154865A (en) * 2022-06-30 2022-10-11 上海英威思医疗科技有限公司 Reinforced catheter
EP4013484A4 (en) * 2019-08-13 2023-10-11 Shanghai Wallaby Medical Technologies Co., Inc. Multi-layer catheter construction
CN117861041A (en) * 2024-01-09 2024-04-12 上海心玮医疗科技股份有限公司 Microcatheter
WO2024139988A1 (en) * 2022-12-28 2024-07-04 先健科技(深圳)有限公司 Suction catheter

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111658966A (en) * 2020-07-03 2020-09-15 为泰医疗器械(深圳)有限公司 Double-channel type micro catheter
CN111672010A (en) * 2020-07-15 2020-09-18 禾木(中国)生物工程有限公司 Micro-catheter
CN114948085A (en) * 2022-06-02 2022-08-30 上海畅德医疗科技有限公司 Perfusion catheter and application thereof
CN116899035A (en) * 2023-07-14 2023-10-20 上海励楷科技有限公司 Intracranial aspiration catheter

Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5971975A (en) * 1996-10-09 1999-10-26 Target Therapeutics, Inc. Guide catheter with enhanced guidewire tracking
US20040153049A1 (en) * 2002-10-10 2004-08-05 Hewitt Todd J. Wire braid-reinforced microcatheter
US20040176740A1 (en) * 2003-03-05 2004-09-09 Scimed Life Systems, Inc. Multi-braid exterior tube
CN104707235A (en) * 2013-12-17 2015-06-17 常州乐奥医疗科技有限公司 Novel micro-catheter
CN205322975U (en) * 2015-12-04 2016-06-22 刘宗军 Through radial artery coronary radiography pipe
CN106823102A (en) * 2017-03-09 2017-06-13 珠海德瑞医疗器械有限公司 A kind of mariages braided blood vessel angiography catheter
CN207137135U (en) * 2017-03-09 2018-03-27 珠海德瑞医疗器械有限公司 A kind of mariages braided blood vessel angiography catheter
CN108601920A (en) * 2015-09-11 2018-09-28 科思瑞公司 Polymeric tubings axis with reinforcement material
CN209884980U (en) * 2018-12-19 2020-01-03 深圳市业聚实业有限公司 Novel micro-catheter

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6355027B1 (en) * 1999-06-09 2002-03-12 Possis Medical, Inc. Flexible microcatheter
JP4837302B2 (en) * 2005-03-25 2011-12-14 川澄化学工業株式会社 Microcatheter
CN101553271B (en) * 2006-09-13 2012-08-29 川澄化学工业株式会社 Microcatheter
JP4743800B2 (en) * 2008-10-11 2011-08-10 朝日インテック株式会社 catheter
JP5446488B2 (en) * 2009-06-11 2014-03-19 住友ベークライト株式会社 Catheter manufacturing method
CN101933821B (en) * 2009-06-30 2014-03-12 上海微创医疗器械(集团)有限公司 Mciro-catheter
JP6578382B2 (en) * 2015-05-29 2019-09-18 コヴィディエン リミテッド パートナーシップ Tapering outer diameter catheter
WO2018042596A1 (en) * 2016-09-01 2018-03-08 朝日インテック株式会社 Catheter
CN206325099U (en) * 2016-10-20 2017-07-14 深圳市业聚实业有限公司 Guiding catheter
WO2020124551A1 (en) * 2018-12-19 2020-06-25 深圳市业聚实业有限公司 Novel microcatheter

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5971975A (en) * 1996-10-09 1999-10-26 Target Therapeutics, Inc. Guide catheter with enhanced guidewire tracking
US20040153049A1 (en) * 2002-10-10 2004-08-05 Hewitt Todd J. Wire braid-reinforced microcatheter
US20040176740A1 (en) * 2003-03-05 2004-09-09 Scimed Life Systems, Inc. Multi-braid exterior tube
CN104707235A (en) * 2013-12-17 2015-06-17 常州乐奥医疗科技有限公司 Novel micro-catheter
CN108601920A (en) * 2015-09-11 2018-09-28 科思瑞公司 Polymeric tubings axis with reinforcement material
CN205322975U (en) * 2015-12-04 2016-06-22 刘宗军 Through radial artery coronary radiography pipe
CN106823102A (en) * 2017-03-09 2017-06-13 珠海德瑞医疗器械有限公司 A kind of mariages braided blood vessel angiography catheter
CN207137135U (en) * 2017-03-09 2018-03-27 珠海德瑞医疗器械有限公司 A kind of mariages braided blood vessel angiography catheter
CN209884980U (en) * 2018-12-19 2020-01-03 深圳市业聚实业有限公司 Novel micro-catheter

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
李毅刚主编: "快速性心律失常介入诊疗临床关键技术", 28 February 2010, 科学技术文献出版社, pages: 23 *

Cited By (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020124551A1 (en) * 2018-12-19 2020-06-25 深圳市业聚实业有限公司 Novel microcatheter
CN109999316A (en) * 2019-04-29 2019-07-12 南通伊诺精密塑胶导管有限公司 A kind of blood vessel microtubular with developing mark function
CN109999316B (en) * 2019-04-29 2021-05-28 南通伊诺精密塑胶导管有限公司 Blood vessel micro-catheter with developing and marking functions
EP4013484A4 (en) * 2019-08-13 2023-10-11 Shanghai Wallaby Medical Technologies Co., Inc. Multi-layer catheter construction
CN110537956A (en) * 2019-10-09 2019-12-06 上海加奇生物科技苏州有限公司 Catheter special for pumping thrombus at far end of cerebral vessel
WO2021068421A1 (en) * 2019-10-09 2021-04-15 上海加奇生物科技苏州有限公司 Special catheter for thrombus aspiration from distal cerebral vessel
CN110947077A (en) * 2019-12-02 2020-04-03 心凯诺医疗科技(上海)有限公司 High-flexibility distal access guiding catheter and preparation method thereof
CN110947077B (en) * 2019-12-02 2024-05-07 心凯诺医疗科技(上海)有限公司 High-flexibility distal end access guide catheter and preparation method thereof
CN111467650A (en) * 2020-05-27 2020-07-31 深圳北芯生命科技有限公司 Micro-catheter
CN114832203A (en) * 2020-05-27 2022-08-02 深圳北芯生命科技股份有限公司 Microcatheter with tapered tip
CN113855992A (en) * 2020-06-30 2021-12-31 微创神通医疗科技(上海)有限公司 A catheter
CN112402060A (en) * 2020-11-02 2021-02-26 金仕生物科技(常熟)有限公司 Delivery system of intervention valve
CN112401973B (en) * 2020-11-19 2022-09-27 上海腾复医疗科技有限公司 Multifunctional sheath tube
CN112401973A (en) * 2020-11-19 2021-02-26 上海腾复医疗科技有限公司 Multifunctional sheath tube
CN112472953A (en) * 2020-12-03 2021-03-12 广东博迈医疗器械有限公司 Braided catheter with reinforcing ribs
CN112472955A (en) * 2020-12-15 2021-03-12 上海融脉医疗科技有限公司 Multi-segment hardness interventional catheter and weaving method thereof
CN113181506A (en) * 2021-04-23 2021-07-30 谱高医疗科技(南京)有限公司 Micro catheter with weaving and spring winding composite structure
CN113198085A (en) * 2021-05-11 2021-08-03 深圳麦普奇医疗科技有限公司 Conveniently-implanted transradial coronary angiography catheter
CN114191685A (en) * 2021-10-19 2022-03-18 深圳北芯医疗科技有限公司 Catheter sheath
CN114699623A (en) * 2022-04-07 2022-07-05 深圳市凯思特医疗科技股份有限公司 Angiography catheter and angiography device
CN114699623B (en) * 2022-04-07 2022-12-27 深圳市凯思特医疗科技股份有限公司 Angiographic catheter and angiographic apparatus
CN114904121B (en) * 2022-04-24 2023-11-17 广州易介医疗科技有限公司 Medical ingress pipe, guiding catheter device thereof and radial artery access catheter system
CN114904121A (en) * 2022-04-24 2022-08-16 广州易介医疗科技有限公司 Medical leading-in tube, guiding catheter device thereof and radial artery access catheter system
CN115154865A (en) * 2022-06-30 2022-10-11 上海英威思医疗科技有限公司 Reinforced catheter
WO2024139988A1 (en) * 2022-12-28 2024-07-04 先健科技(深圳)有限公司 Suction catheter
CN117861041A (en) * 2024-01-09 2024-04-12 上海心玮医疗科技股份有限公司 Microcatheter
CN117861041B (en) * 2024-01-09 2024-07-16 上海心玮医疗科技股份有限公司 Microcatheter

Also Published As

Publication number Publication date
JP2022515796A (en) 2022-02-22
WO2020124551A1 (en) 2020-06-25

Similar Documents

Publication Publication Date Title
CN109498957A (en) A kind of novel microtubular
CN209884980U (en) Novel micro-catheter
JP2545981B2 (en) Balloon catheter
CN108514677A (en) A kind of microtubular
JP4547374B2 (en) Medical device including unbalanced reinforcing member and method for manufacturing the same
CN2889337Y (en) Microtube
US20060253102A1 (en) Non-expandable transluminal access sheath
CN108025160A (en) Guiding extension conduit with fill openings
JP2001518325A (en) Soft-tip high-performance braided catheter
US6740073B1 (en) Guiding catheter reinforcement with angled distal end
CN209137697U (en) A kind of microtubular
CN218420634U (en) Reinforced catheter with braided middle layer catheter
WO2022166538A1 (en) Catheter reinforcement layer and catheter
CN111035432A (en) Thrombus cleaning brush device
CN112354065A (en) Medical catheter
CN218420636U (en) Reinforced catheter with spiral diffusion stress tube
CN218420635U (en) Reinforcing pipe with interval fretwork formula diffusion stress pipe
CN218685686U (en) Reinforced catheter
CN218280297U (en) Reinforcing pipe with spiral spring intermediate layer pipe
CN111888622B (en) Stepless gradual change type catheter
CN218552889U (en) Sacculus pipe based on double-deck hypotube
CN114081681B (en) Trans-femoral valve delivery system
CN211584832U (en) Distal access catheter
JPH08308932A (en) Sliding catheter
CN115154865A (en) Reinforced catheter

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination