CN218741679U

CN218741679U - Agitating unit is used in production of carbamatinib

Info

Publication number: CN218741679U
Application number: CN202222197206.0U
Authority: CN
Inventors: 赵跃; 陈晨; 万新锋; 杨延召; 张鹏伟; 张明千; 王杰明; 周深; 程壮壮
Original assignee: Anqing Duohui Biotechnology Co ltd
Current assignee: Anqing Duohui Biotechnology Co ltd
Priority date: 2022-08-18
Filing date: 2022-08-18
Publication date: 2023-03-28
Anticipated expiration: 2032-08-18

Abstract

The utility model discloses an agitating unit is used in production of carmatinib, the power distribution box comprises a box body, the equal fixedly connected with pillar in the lower extreme left and right sides of box, the inboard of box is equipped with the stirring storehouse, the inboard in stirring storehouse is equipped with rabbling mechanism, the outside of rabbling mechanism is equipped with rubbing crusher and constructs, the lower extreme in stirring storehouse is equipped with the discharging pipe. The above structure is adopted in the utility model, on the basis of rabbling mechanism operation, utilize the jack-post to pass through sprocket and outside chain linkage first axostylus axostyle and rotate in crushing case, and the right-hand member of first axostylus axostyle and the right-hand member of second axostylus axostyle carry out the syntropy motion meshing through the gear, make first on the first axostylus axostyle roll and the second on the second axostylus axostyle roll can mutually support smash the raw materials in crushing case, thereby can improve the quality that the raw materials mixes, and reduce the equipment input of enterprise, the machine need not be changed simultaneously, the loss of raw materials is reduced.

Description

Agitating unit is used in production of carbamatinib

Technical Field

The utility model belongs to the technical field of the production of carbamatinib, in particular to agitating unit is used in the production of carbamatinib.

Background

Carbamatinib is a potent, oral, selective, ATP-competitive inhibitor of c-Met kinase. The carbaminib can effectively inhibit the proliferation and migration of c-met dependent tumor cells, can effectively induce apoptosis and has antitumor activity.

Two kinds of powder raw materials of bromoquinoline and bis dibenzylidene acetone palladium need to be mixed and stirred in the production process of the carbamatinib, however, a special smashing device is needed to be used for smashing a small amount of hard particles contained in the raw materials before the raw materials are stirred by a stirring device in the prior art, then the smashed raw materials are collected, and finally the smashed raw materials are put into the stirring device to be stirred, smashing equipment is added in the implementation process, so that the input cost is increased, meanwhile, the raw materials enter another equipment from one equipment to invisibly influence the yield problem of the raw materials, and therefore technical improvement is needed.

SUMMERY OF THE UTILITY MODEL

To the problem of mentioning in the background art, the utility model aims at providing a agitating unit is used in camatinib production to solve the problem of mentioning in the above background art.

The above technical object of the present invention can be achieved by the following technical solutions:

the utility model provides a stirring apparatus for producing of carmatinib, the power distribution box comprises a box body, the equal fixedly connected with pillar in the lower extreme left and right sides of box, the inboard of box is equipped with the stirring storehouse, the inboard in stirring storehouse is equipped with rabbling mechanism, the outside of rabbling mechanism is equipped with rubbing crusher and constructs, the lower extreme in stirring storehouse is equipped with the discharging pipe, the front of box is equipped with the blown down tank, the lower extreme of discharging pipe stretches into the blown down tank, the upper end symmetry fixed mounting of box has crushing case, the upper end of crushing case is equipped with the hopper, the lower extreme and the stirring storehouse of crushing case lead to each other, the lower extreme adhesive connection of pillar has the shock pad.

Further, as preferred technical scheme, rabbling mechanism includes the motor, motor fixed mounting is in the left side of box, the inside rotation in stirring storehouse is connected with the jack-post, the equal symmetry fixed mounting in both ends about the jack-post has the stirring frame, the outside fixed mounting of jack-post has the board of stirring, the outside of stirring the board is equipped with the round hole, the box wall of box and the output fixed connection of motor are run through to the left end of jack-post, rubbing crusher constructs the left end outer wall of establishing at the jack-post.

Further, as preferred technical scheme, rubbing crusher constructs including first axostylus axostyle and second axostylus axostyle, first axostylus axostyle and second axostylus axostyle all rotate to be connected in the inside of smashing the case, the outside symmetry fixed mounting of first axostylus axostyle has first roller, the outside fixed mounting of second axostylus axostyle has the second roller, the left end of first axostylus axostyle runs through the left crushing case in box upper end, the left end outer wall of the left end of first axostylus axostyle and the equal fixed mounting of the left end outer wall of jack-post has the sprocket, the sprocket of jack-post left end outer wall, the sprocket outside meshing of first axostylus axostyle left end outer wall is connected with same chain, the right-hand member of first axostylus axostyle and the right-hand member of second axostylus axostyle all run through crushing case fixed mounting on box upper end right side have the gear, the gear of first axostylus axostyle right-hand member and the gear on second axostylus axostyle right side are the meshing connection.

Further, as preferred technical scheme, the crushing case outside fixed mounting on box upper end right side has the protecting crust, the protecting crust covers the gear.

Further, as preferred technical scheme, the lower extreme of hopper stretches into crushing incasement portion fixed mounting has flat mouth.

Further, as preferred technical scheme, the left side fixed mounting of box has the mounting panel, motor fixed mounting is in the upper end of mounting panel.

Further, as preferred technical scheme, the collection box has been placed to the inboard of blown down tank, the collection box is established under the discharging pipe.

To sum up, the utility model discloses mainly have following beneficial effect:

firstly, the output end of a motor is utilized to drive a shaft column to rotate in a stirring bin, raw materials outside the stirring bin can be mixed and stirred through an external stirring frame, rubber plates arranged outside the shaft column in a staggered mode can be used for core stirring, round holes are additionally formed in a stirring plate, two raw materials can be further stirred and mixed through the round holes in the stirring process of the stirring plate, and therefore the stirring and mixing efficiency of the raw materials can be improved;

the second, on the basis of rabbling mechanism operation, utilize the jack-post to pass through the sprocket and rotate in crushing case with outside chain linkage first axostylus axostyle, and the right-hand member of first axostylus axostyle and the right-hand member of second axostylus axostyle carry out the syntropy motion meshing through the gear, make first roller and the second roller on the second axostylus axostyle on the first axostylus axostyle can mutually support and smash the raw materials in crushing case, thereby can improve the quality that the raw materials mixes, and reduce the equipment input of enterprise, need not change the machine simultaneously, the loss of raw materials has been reduced.

Drawings

Fig. 1 is a perspective view of the present invention;

fig. 2 is a schematic structural diagram of the present invention;

figure 3 is a cross-sectional view of the crushing box of the present invention.

Reference numerals: 1. the device comprises a box body, 2, a support column, 3, a stirring bin, 4, a shock pad, 5, a stirring mechanism, 501, a stirring frame, 502, a stirring plate, 503, a round hole, 504, a shaft column, 505, a motor, 6, a mounting plate, 7, a discharging pipe, 8, a collecting box, 9, a crushing mechanism, 901, a chain wheel, 902, a chain, 903, a first shaft rod, 904, a gear, 905, a first crushing roller, 906, a second shaft rod, 907 and a second crushing roller, 10, a crushing box, 11, a protective shell, 12, a flat nozzle, 13, a discharging groove, 14 and a hopper.

Detailed Description

The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention.

Example 1

Referring to fig. 1-3, the stirring apparatus for producing camatinib in this embodiment includes a box 1, pillars 2 are fixedly connected to both left and right sides of a lower end of the box 1, a stirring bin 3 is disposed inside the box 1, a stirring mechanism 5 is disposed inside the stirring bin 3, a crushing mechanism 9 is disposed outside the stirring mechanism 5, a discharging pipe 7 is disposed at a lower end of the stirring bin 3, a discharging groove 13 is disposed on a front surface of the box 1, a lower end of the discharging pipe 7 extends into the discharging groove 13, crushing boxes 10 are symmetrically and fixedly mounted at an upper end of the box 1, a hopper 14 is disposed at an upper end of the crushing boxes 10, a lower end of the crushing boxes 10 is connected to the stirring bin 3, and shock pads 4 are bonded to lower ends of the pillars 2, so that stability of the lower ends of the pillars 2 can be improved by disposing the shock pads 4; the lower end of the hopper 14 extends into the crushing box 10 and is fixedly provided with the flat nozzle 12, and the flat nozzle 12 is arranged at the lower end of the hopper 14, so that raw materials can be conveniently guided between the first rolling roller 905 and the second rolling roller 907 to be crushed and rolled; the mounting plate 6 is fixedly mounted on the left side of the box body 1, the motor 505 is fixedly mounted at the upper end of the mounting plate 6, and the mounting plate 6 is arranged on the left side of the box body 1, so that the motor 505 can be conveniently mounted; collection box 8 has been placed to the inboard of blown down tank 13, collects box 8 and establishes under discharging pipe 7, collects box 8 through the inboard setting at blown down tank 13, can conveniently collect the mixture.

Example 2

Referring to fig. 2, on the basis of embodiment 1, in order to achieve the purpose of efficient stirring, the present embodiment innovatively designs a stirring mechanism 5, specifically, the stirring mechanism 5 includes a motor 505, the motor 505 is fixedly installed on the left side of the box 1, a shaft column 504 is rotatably connected inside the stirring bin 3, stirring frames 501 are symmetrically and fixedly installed at both upper and lower ends of the shaft column 504, a stirring plate 502 is fixedly installed at the outer side of the shaft column 504, a circular hole 503 is formed in the outer side of the stirring plate 502, the left end of the shaft column 504 penetrates through the box wall of the box 1 and is fixedly connected to the output end of the motor 505, a crushing mechanism 9 is installed on the outer wall of the left end of the shaft column 504, the shaft column 504 is driven by the output end of the motor 505 to rotate in the stirring bin 3, through the external stirring frame 501, the raw materials inside the stirring bin 3 can be mixed and stirred, the rubber plates staggered outside the shaft column 504 can stir the core, the circular hole 503 is added to the stirring plate 502, and the two raw materials can be further stirred and mixed through the circular hole 503 in the stirring process of the stirring plate 502.

Example 3

Referring to fig. 1 to 3, in this embodiment, on the basis of embodiment 1, in order to achieve the purpose of conveniently performing crushing treatment on raw materials, the crushing mechanism 9 is innovatively designed in this embodiment, specifically, the crushing mechanism 9 includes a first shaft 903 and a second shaft 906, the first shaft 903 and the second shaft 906 are both rotatably connected inside the crushing box 10, a first rolling roller 905 is symmetrically and fixedly installed on the outer side of the first shaft 903, a second rolling roller 907 is fixedly installed on the outer side of the second shaft 906, the left end of the first shaft 903 penetrates through the crushing box 10 on the left side of the upper end of the box body 1, a sprocket 901 is fixedly installed on the left end of the first shaft 903 and the outer wall of the left end of the shaft 504, a sprocket 901 on the outer wall of the left end of the shaft 504, and the same chain 902 is engaged and connected on the outer side of the sprocket 901 on the outer wall of the left end of the first shaft 903, the right end of the first shaft lever 903 and the right end of the second shaft lever 906 both penetrate through the crushing box 10 on the right side of the upper end of the box body 1 and are fixedly provided with a gear 904, the gear 904 on the right end of the first shaft lever 903 and the gear 904 on the right side of the second shaft lever 906 are in meshed connection, through the arrangement of the crushing mechanism 9, on the basis of the operation of the stirring mechanism 5, the shaft column 504 is used for being linked with an external chain 902 through a chain wheel 901 to enable the first shaft lever 903 to rotate in the crushing box 10, and the right end of the first shaft lever 903 and the right end of the second shaft lever 906 are in same-direction movement meshing through the gear 904, so that a first rolling roller 905 on the first shaft lever 903 and a second rolling roller 907 on the second shaft lever 906 can be matched with each other to crush raw materials in the crushing box 10; the crushing case 10 outside fixed mounting on box 1 upper end right side has protecting crust 11, and protecting crust 11 covers gear 904, through set up protecting crust 11 in box 1 upper end, can conveniently cover the protection to gear 904.

The use principle and the advantages are as follows: when the stirring device is used, two powder raw materials of bromoquinoline and bis-dibenzylidene acetone palladium are firstly placed in the corresponding hopper 14 and then enter the crushing box 10 through the flat nozzle 12, the output end of the motor 505 is used for driving the shaft column 504 to rotate in the stirring bin 3, the raw materials outside the stirring bin 3 can be mixed and stirred through the external stirring frame 501, the rubber plates arranged outside the shaft column 504 in a staggered mode can be used for stirring the core, the circular hole 503 is additionally formed in the stirring plate 502, the two raw materials pass through the circular hole 503 in the stirring process of the stirring plate 502, the stirring and mixing can be further carried out, meanwhile, on the basis of operation of the stirring mechanism 5, the shaft column 504 is used for being linked with the first shaft rod 903 to rotate in the crushing box 10 through the chain wheel 901 and the external chain 902, the right end of the first shaft rod 903 and the right end of the second shaft rod 906 are meshed through the same-direction movement of the gear 904, the first rolling roller 905 on the first shaft rod 903 and the second rolling roller 907 on the second shaft rod 906 can be matched with each other to crush the crushing box 10 to crush the raw materials, after stirring is completed, the discharging pipe 7 is opened, and then the collecting box 8 can be collected through the shaft rod 906.

Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.

Claims

1. The utility model provides a agitating unit is used in production of carbamatinib which characterized in that: including box (1), the equal fixedly connected with pillar (2) of the lower extreme left and right sides of box (1), the inboard of box (1) is equipped with stirring storehouse (3), the inboard of stirring storehouse (3) is equipped with rabbling mechanism (5), the outside of rabbling mechanism (5) is equipped with rubbing crusher structure (9), the lower extreme of stirring storehouse (3) is equipped with discharging pipe (7), the front of box (1) is equipped with blown down tank (13), blown down tank (13) are stretched into to the lower extreme of discharging pipe (7), the upper end symmetry fixed mounting of box (1) has crushing case (10), the upper end of crushing case (10) is equipped with hopper (14), the lower extreme and the stirring storehouse (3) of crushing case (10) communicate with each other, the lower extreme adhesive connection of pillar (2) has shock pad (4).

2. The stirring device for producing carbaminib according to claim 1, wherein: rabbling mechanism (5) are including motor (505), motor (505) fixed mounting is in the left side of box (1), the inside rotation in stirring storehouse (3) is connected with jack-post (504), the equal symmetrical fixed mounting in both ends has stirring frame (501) about jack-post (504), the outside fixed mounting of jack-post (504) has stirs board (502), the outside of stirring board (502) is equipped with round hole (503), the left end of jack-post (504) runs through the tank wall of box (1) and the output fixed connection of motor (505), the left end outer wall in jack-post (504) is established in rubbing crusher structure (9).

3. The stirring device for producing carbamatinib according to claim 2, characterized in that: the crushing mechanism (9) comprises a first shaft lever (903) and a second shaft lever (906), the first shaft lever (903) and the second shaft lever (906) are rotatably connected inside the crushing box (10), a first rolling roller (905) is symmetrically and fixedly mounted on the outer side of the first shaft lever (903), a second rolling roller (907) is fixedly mounted on the outer side of the second shaft lever (906), the left end of the first shaft lever (903) penetrates through the crushing box (10) on the left side of the upper end of the box body (1), a chain wheel (901) is fixedly mounted on the left end of the first shaft lever (903) and the outer wall of the left end of the shaft column (504), a gear (904) is fixedly mounted on the outer wall of the left end of the shaft column (504), the outer side of the chain wheel (901) on the outer wall of the left end of the first shaft lever (903) is connected with the same chain (902) in an engaged manner, the right end of the first shaft lever (903) and the right end of the second shaft lever (906) penetrate through the crushing box (10) on the right side of the upper end of the box body (1), and a gear (904) is connected with the gear (904) in an engaged manner.

4. The stirring device for producing carbamatinib according to claim 3, characterized in that: the crushing case (10) outside fixed mounting on box (1) upper end right side has protecting crust (11), gear (904) are covered by protecting crust (11).

5. Stirring device is used in production of carbamatinib according to claim 1, characterized in that: the lower end of the hopper (14) extends into the crushing box (10) and is fixedly provided with a flat nozzle (12).

6. The stirring device for producing carbamatinib according to claim 2, characterized in that: the left side fixed mounting of box (1) has mounting panel (6), motor (505) fixed mounting is in the upper end of mounting panel (6).

7. The stirring device for producing carbaminib according to claim 1, wherein: a collecting box (8) is placed on the inner side of the discharge chute (13), and the collecting box (8) is arranged under the discharge pipe (7).