CN218539671U - Embryo transfer device of adjustable negative pressure - Google Patents

Abstract

The utility model discloses an embryo transfer device of adjustable negative pressure, including pipettor rifle head, flow regulator, the hose of breathing in, filter, silica gel sealed tube and pasteur's straw. The pipette head comprises a filter element, the pipette head is a conical pipe body with a large aperture at one end and a small aperture at the other end, the small aperture end is inserted into the rear port of the air suction hose, the flow regulator is fixedly connected to the air suction hose, the filter is a 0.22 mu m semipermeable membrane, the rear end of the filter is inserted into the front port of the air suction hose, and the filter and the pasteur suction pipe are fixedly connected through a silica gel sealing pipe. The utility model discloses simple structure, convenient for material collection, low cost practices thrift a lot of times, reduces the possibility that the embryo lost and avoids misoperation to bring the harm for the embryo, reduces the tired sense of hand muscle simultaneously, can not bring the damage for muscle and joint, can prevent impurity pollution embryo such as the bacterium in the air and in the oral cavity.

Description

Embryo transfer device of adjustable negative pressure

Technical Field

The utility model relates to a medical apparatus in reproductive medicine, in particular to an embryo transfer device with adjustable negative pressure.

Background

Infertility is a worldwide problem affecting the harmony of families and society, and about 10% -20% of women of childbearing age worldwide suffer from different types of infertility. Tube infant technology offers the possibility of many infertility patients gestating new lives. Currently, the tube baby technology has been developed to the fourth generation, and the main methods are: firstly, taking the egg cell nucleus of a female, transplanting the egg cell nucleus into a high-quality enucleated egg cell, and recombining the egg cell nucleus and the enucleated egg cell into an egg cell with stronger vitality: the recombined egg cells are transplanted into the mother uterus after in vitro fertilization to form embryos, and the subsequent development is completed.

In vitro fertilization refers to a technique in which sperm and eggs complete the fertilization process in an environment artificially controlled in vitro. The fertilized ovum is cultured to form an early embryo which is then transplanted into the uterus of the female. However, the diameter of the ovum and embryo is about 120-150 μm, so workers need to transfer the ovum and embryo when in vitro fertilization and embryo transfer, and the transfer often needs some auxiliary medical appliances. The device commonly used for transferring embryos is a pasteur pipette with a rubber head, and workers complete the transfer process by squeezing the rubber head to generate negative pressure to suck embryos from a culture dish or spit embryos out of the pasteur pipette. However, the device has a plurality of defects that when the squeezing force is not good for workers to master, the great air flow is generated due to the excessive force, and the embryo is lost. In addition, the Pasteur pipette is long, the hand of a worker needs to be in a suspended state during operation, accurate embryo transfer is difficult to complete under the state, and the fatigue of the hand is increased and the muscle and the joint are damaged for a long time. Therefore, in order to use the conventional embryo transfer device, it takes a long time for the worker to exercise the manipulation method.

SUMMERY OF THE UTILITY MODEL

An object of the utility model is to provide an embryo transfer device of adjustable negative pressure to solve a great deal of problems that above-mentioned background art tradition embryo transfer utensil exists.

In order to achieve the above purpose, the utility model provides the following technical scheme.

An embryo transfer device capable of adjusting negative pressure comprises a pipette head, a flow regulator, an air suction hose, a filter, a silica gel sealing tube and a pasteur suction tube; the pipette head is a conical pipe body with a large aperture at one end and a small aperture at the other end, the small aperture end is inserted into the rear port of the air suction hose, the flow regulator is fixedly connected to the air suction hose, the rear end of the filter is inserted into the front port of the air suction hose, and the filter is fixedly connected with the pasteur suction pipe through a silica gel sealing pipe.

Further, the pipette tip comprises a filter element, and the filter element is arranged in the conical tube body and is arranged at one end close to the pipette tip with a large aperture. The filter element plays a role in primary filtration of gas exhaled by a worker when the worker transfers embryos from the Pasteur pipette, and the chance of embryo pollution can be reduced due to bacteria and impurities contained in the cavity.

Further, the flow regulator changes the gas flow by changing the cross-sectional area of the suction hose through the extrusion of the pulley. The flow regulator prevents the operator from causing misoperation or embryo loss due to overlarge inspiration or expiration flow, and can accurately control the flow regulator to suck and transfer the embryo.

Furthermore, the suction hose is made of latex.

Further, the length of the suction hose is 10-15cm.

Further, the filter is a 0.22 μm semi-permeable membrane. The thickness of the semipermeable membrane is about 100-130 μm, and the semipermeable membrane with the aperture of 0.22 μm can retain most bacteria on the surface of the filter membrane, thereby providing good bacteria-blocking effect and playing a role in further filtration.

Further, the inner diameter of the suction hose is equal to the outer diameter of the upper port of the filter. This is to enhance the seal of the device and prevent contamination of the embryos by external agents during the removal process.

Furthermore, the inner diameter of the silica gel sealing tube is equal to the outer diameter of the pasteur sucker and the outer diameter of the lower port of the filter (5).

Further, a tampon is disposed within the pasteur pipette at a location below the filter. The purpose of this is to provide buffering and further filtration to ensure sterile handling.

Furthermore, the aperture of the small-caliber end of the pasteur pipette is 140-170 μm. The diameter of the embryo is 120-150 μm, which ensures that the embryo can be sucked into the pasteur pipette.

Furthermore, the Basist sucker is integrally formed by injection molding of a transparent glass material.

Compared with the prior art, the utility model discloses there is following beneficial effect:

the utility model discloses simple structure, convenient for material collection, low cost, compare in traditional extrusion inspiratory device, this transfer device is breathed in through the manual work and can be absorbed with control flow regulator more accurate control, practice thrift a lot of times, reduce the possibility that the embryo lost and avoid misoperation to bring the harm for the embryo, reduce the tired sense of hand muscle simultaneously, can not bring the damage for muscle and joint, the filter core that is equipped with, filter and tampon can prevent impurity pollution embryos such as bacterium in the air and the oral cavity, the pipettor rifle head as the suction nozzle can be changed at any time, clean health.

Drawings

In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings required to be used in the embodiments will be briefly described below, and it is obvious that the drawings in the following description are only some embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to these drawings without creative efforts.

Fig. 1 is a schematic structural view of the negative pressure adjustable embryo transfer device of the present invention.

Reference numerals: 1. the device comprises a pipette head, 2, a filter element, 3, a flow regulator, 4, an air suction hose, 5, a filter, 6, a silica gel sealing tube, 7, a cotton plug, 8 and a Basette suction pipe.

Detailed Description

The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the present application, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by a person skilled in the art without creative efforts belong to the protection scope of the present invention.

The following, with reference to the drawings and the detailed description, further description of the present invention is made:

referring to fig. 1, an embryo transfer device capable of adjusting negative pressure according to an embodiment of the present invention includes a pipette tip 1, a flow regulator 3, a suction hose 4, a filter 5, a silica gel sealing tube 6, and a pasteur suction tube 8; the pipette tip 1 is a conical tube body with a large aperture at one end and a small aperture at the other end, the small aperture end is inserted into the rear port of the air suction hose 4, the flow regulator 3 is fixedly connected to the air suction hose 4, the rear end of the filter 5 is inserted into the front port of the air suction hose 4, and the filter 5 and the pasteur pipette 8 are fixedly connected through a silica gel sealing tube 6.

Further, the pipette tip 1 comprises a filter element 2, and the filter element 2 is arranged in the conical tube body and is arranged at one end close to the pipette tip 1 with a large aperture. The filter element plays a role in primary filtration of gas exhaled by a worker when the worker transfers embryos from the Pasteur pipette 8, and the opportunity of embryo pollution can be reduced due to bacteria and impurities contained in the cavity.

Further, the flow regulator 3 changes the gas flow by changing the cross-sectional area of the suction hose 4 by means of pulley squeezing. The flow regulator prevents the operator from causing misoperation or embryo loss due to overlarge inspiration or expiration flow, and can accurately control the flow regulator to suck and transfer the embryo.

Further, the suction hose 4 is made of latex.

Further, the length of the suction hose 4 is 10-15cm.

Further, the filter 5 is a 0.22 μm semipermeable membrane. The semi-permeable membrane with the thickness of about 100-130 mu m and the pore diameter of 0.22 mu m can retain most of bacteria on the surface of the filter membrane, provide good bacteria-blocking effect and play a role in further filtration.

Further, the inner diameter of the suction hose 4 is equal to the outer diameter of the upper end of the filter 5. This is to enhance the seal of the device and prevent contamination of the embryos by external agents during the removal process.

Further, the inner diameter of the silica gel sealing tube 6 is equal to the outer diameter of the pasteur pipette 8 and the outer diameter of the lower port of the filter 5.

Further, a tampon 7 is arranged inside the top end of the pasteur straw 8, and the tampon 7 is positioned below the filter 5. The purpose of this is to provide buffering and further filtration to ensure aseptic handling.

Furthermore, the aperture of the small-caliber end of the Pasteur pipette 8 is 140-170 μm. The diameter of the embryo is 120-150 μm, which ensures that the embryo can be sucked into the pasteur pipette 8.

Further, the pasteur pipette 8 is integrally formed by injection molding of a transparent glass material.

The utility model discloses a use method does:

during operation, the flow regulator 3 is fixed on the air suction hose 4, the end with the smaller diameter of the pipette tip 1 is inserted into the rear end port of the air suction hose 4, the rear end port of the filter 5 is inserted into the front end port of the air suction hose 4, the front end port of the filter 5 is fixedly connected with the pasteur suction pipe 7 through the silica gel sealing pipe 6, the end with the smaller diameter of the pasteur suction pipe 8 is aligned with an embryo to be sucked, the flow regulator 3 is regulated to enable the flow to be minimum, air suction is carried out in a manual air suction mode, the flow regulator 3 is gradually opened to regulate the negative pressure until the embryo is accurately controlled to be sucked, so that the embryo is transferred into the pasteur suction pipe 8 to be transferred, the pipette tip 1 is blocked to ensure that the pressure in the pasteur suction pipe 8 is unchanged, when the embryo is transferred into the next culture dish, the blocked pipette tip 1 is loosened and the embryo is breathed into the pipette tip 1, impurities such as bacteria in the oral cavity can be filtered by the filter element 2, the filter 5 and the pipette 7, sterile operation is ensured, and the embryo is made to fall off from the embryo from the culture dish due to finish the embryo transfer of the embryo due to the effect of the pressure.

By the above embodiment, it can be derived that: the utility model discloses simple structure, convenient for material collection, low cost, compare in traditional extrusion inspiratory device, this transfer device is breathed in through the manual work and can be absorbed with control flow regulator more accurate control, practice thrift a lot of times, reduce the possibility that the embryo lost and avoid misoperation to bring the harm for the embryo, reduce the tired sense of hand muscle simultaneously, can not bring the damage for muscle and joint, the filter core that is equipped with, filter and tampon can prevent impurity pollution embryos such as bacterium in the air and the oral cavity, the pipettor rifle head as the suction nozzle can be changed at any time, clean health.

Finally, it should be noted that: the above embodiments are only used to illustrate the technical solution of the present invention, and not to limit the same; although the present invention has been described in detail with reference to the foregoing embodiments, those skilled in the art will understand that: the technical solutions described in the foregoing embodiments may still be modified, or some technical features may be equivalently replaced; such modifications and substitutions do not depart from the spirit and scope of the embodiments of the present invention.

Claims (10)

1. An embryo transfer device capable of adjusting negative pressure is characterized by comprising a pipette head (1), a flow regulator (3), an air suction hose (4), a filter (5), a silica gel sealing tube (6) and a Pasteur suction tube (8); the pipette tip (1) is a conical tube body with a large aperture at one end and a small aperture at the other end, the end with the small aperture is inserted into the rear port of the air suction hose (4), the flow regulator (3) is fixedly connected to the air suction hose (4), the rear end of the filter (5) is inserted into the front port of the air suction hose (4), and the filter (5) and the pasteur suction pipe (8) are fixedly connected through a silica gel sealing pipe (6).

2. The negative pressure adjustable embryo transfer device according to claim 1, wherein the pipette tip (1) comprises a filter element (2), and the filter element (2) is arranged in the conical tube and is arranged at one end close to the pipette tip (1) with a large aperture.

3. The embryo transfer device with adjustable negative pressure according to claim 1, wherein the flow regulator (3) changes the air flow by changing the cross-sectional area of the suction hose (4) through pulley extrusion.

4. An adjustable negative pressure embryo transfer device according to claim 1, wherein the suction hose (4) is made of latex.

5. An embryo transfer device with adjustable negative pressure according to claim 1, characterized in that the length of the suction hose (4) is 10-15cm.

6. An embryo transfer device with adjustable negative pressure according to claim 1, characterized in that the filter (5) is a 0.22 μm semi-permeable membrane.

7. An adjustable negative pressure embryo transfer device according to claim 1, wherein the inner diameter of the suction hose (4) is equal to the outer diameter of the port on the filter (5).

8. The negative pressure adjustable embryo transfer device according to claim 1, wherein the inner diameter of the silica gel sealing tube (6) is equal to the outer diameter of the pasteur pipette (8) and the outer diameter of the lower port of the filter (5).

9. An adjustable negative pressure embryo transfer device according to claim 1, wherein a tampon (7) is arranged inside the pasteur pipette (8) at a position below the filter (5).

10. The negative pressure adjustable embryo transfer device according to claim 1, wherein the aperture of the small-bore end of the pasteur pipette (8) is 140-170 μm.

Images