CN218530672U - D-dimer assay reagent preparation is with shaking mixing arrangement - Google Patents

D-dimer assay reagent preparation is with shaking mixing arrangement Download PDF

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Publication number
CN218530672U
CN218530672U CN202222392662.0U CN202222392662U CN218530672U CN 218530672 U CN218530672 U CN 218530672U CN 202222392662 U CN202222392662 U CN 202222392662U CN 218530672 U CN218530672 U CN 218530672U
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China
Prior art keywords
movable plate
workbench
fly leaf
workstation
sliding block
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CN202222392662.0U
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Chinese (zh)
Inventor
陈永强
余占江
尹欢
常慧
徐敏
任祥
陈沛
王沁慧
石钰婷
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Jiangsu Aoya Biological Technology Co ltd
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Jiangsu Aoya Biological Technology Co ltd
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Abstract

The utility model provides a D-dimer measuring reagent preparation is with vibrating mixing arrangement, including workstation and guiding mechanism, the workstation upper end is equipped with two guide rails, is equipped with the fly leaf between two guide rails, and the fly leaf is arranged in the workstation top and is connected with the rocker subassembly of establishing in workstation center department, and the fly leaf upper end is equipped with clamping board, and clamping board rotates with the fly leaf to be connected and cooperates with the gear rotation mechanism of establishing between fly leaf and clamping board. The utility model discloses it has the difference with traditional shock mixing arrangement, it rotates the clamping board and connects in the fly leaf upper end, and the rocker subassembly of workstation upper end passes through the slider connecting piece and is connected with the fly leaf, and the crank rocker mechanism of its formation can drive the fly leaf at workstation top horizontal reciprocating motion, and during the horizontal action of fly leaf, the clamping board can be synchronous revolution under gear rotation mechanism's cooperation, makes the reagent pipe in rocking with wave and the mixed effect is even, efficient.

Description

D-dimer assay reagent preparation is with shaking mixing arrangement
Technical Field
The utility model relates to a mixing arrangement especially relates to a D-dimer measuring reagent preparation is with vibrating mixing arrangement.
Background
The D-dimer is a specific degradation product generated by crosslinking fibrin monomer with activated factor XIII and hydrolyzing with plasmin, and is a specific fibrinolysis process marker. The D-dimer is derived from a plasmin-solubilized cross-linked fibrin clot. Among fibrinolytic degradation products, only the D-dimer cross-linked fragment may reflect thrombolytic activity after thrombosis. Therefore, in theory, the quantitative detection of D-dimer can quantitatively reflect the thrombolytic effect of the drug, and can be used for diagnosing and screening newly formed thrombus. Before the D-dimer measurement reagent is tested, the reagent needs to be uniformly mixed and then tested, the reagent is dissolved and mixed, so that chemical components in the reagent can be conveniently detected, and during preparation, the test reagent needs to be uniformly stirred so as to fully react the chemical components in the reagent. To simplify this step, the process is mostly performed by using a mechanical oscillation device.
The utility model discloses a utility model patent of publication (announcement) number CN213699661U discloses a reagent mixed oscillation equipment for inspection, including the bottom plate, the one end of the upside fixed connection square plate of bottom plate, one side fixed connection motor support of square plate, the upside fixed connection motor of motor support, the output shaft of motor passes the square plate, the one end of the output shaft tip fixed connection connecting rod one of motor, the other end swing joint of connecting rod one vibrates the mechanism. The oscillating mechanism on the oscillating device realizes oscillating and mixing of the reagent through the reciprocating oscillation of the oscillating block. Since the reciprocating swing of the swing block is performed only in one direction, the fluctuation range of the liquid agent in the test tube is relatively small when the oscillating mixing is performed, and the mixing efficiency is not high. Therefore, the utility model provides a D-dimer assay reagent preparation is with shaking mixing arrangement in order to solve the problem that exists among the prior art.
SUMMERY OF THE UTILITY MODEL
To the problem, the utility model provides a D-dimer survey reagent preparation is with shaking mixing arrangement for solve current shaking mixing arrangement, its reciprocating motion of swing piece only goes on towards a direction, consequently when shaking the mixture, the fluctuation range of in vitro liquid can be less, has the shortcoming that mixing efficiency is not high.
For realizing the purpose of the utility model, the utility model discloses a following technical scheme realizes: a vibration mixing device for preparing a D-dimer measuring reagent comprises a workbench and a guide mechanism, wherein two guide rails are arranged at the upper end of the workbench, a movable plate is arranged between the two guide rails, and the movable plate is arranged above the workbench and connected with a rocker assembly arranged at the center of the workbench;
the guide mechanism comprises a horizontal guide piece and a sliding block connecting piece, the horizontal guide piece is arranged at the matching position of the two ends of the movable plate and the guide rail, and the sliding block connecting piece is arranged at the matching position of the rocker assembly and the lower end of the movable plate.
The further improvement lies in that: the rocker assembly comprises a connecting rod and a driving motor, the connecting rod is installed at the upper end of the workbench, one end of the connecting rod is fixedly connected with the top end of a rotating shaft arranged at the center of the workbench, and the other end of the connecting rod is arranged below the movable plate and movably connected with the movable plate through a sliding block connecting piece;
the driving motor is installed at the lower extreme of workstation, and driving motor output and pivot bottom fixed connection.
The further improvement lies in that: the gear swing machine comprises a mounting shaft and a toothed plate, the top end of the mounting shaft is fixed at the center of the lower end face of the clamping plate, the top end of the mounting shaft is rotatably connected with the upper end of the movable plate, and a transmission gear is sleeved outside the shaft body of the mounting shaft;
the toothed plate is arranged on one side of the transmission gear, teeth matched with the transmission gear are arranged on the toothed plate, and two ends of the toothed plate are fixedly connected with a support arranged at the upper end of the workbench.
The further improvement is that: the horizontal guide part comprises idler wheels arranged at two ends of the movable plate, and the idler wheels are arranged in guide grooves formed in one sides of the guide rail surfaces facing the movable plate and are in rolling fit with the guide grooves.
The further improvement lies in that: the sliding block connecting piece comprises a sliding groove arranged at the lower end of the movable plate, a sliding block is arranged in the sliding groove, the sliding block is in sliding fit with the sliding groove, and the bottom end of the sliding block is hinged with one end of the connecting rod, which is located below the movable plate.
The further improvement lies in that: the lower end of the workbench is provided with two supporting seats, the two supporting seats are symmetrically arranged on two sides of the driving motor and fixedly connected with the workbench, and the lower end face of each supporting seat is provided with a rubber gasket.
The utility model has the advantages that: the clamping plate is rotatably connected to the upper end of the movable plate, the rocker assembly at the upper end of the workbench is connected with the movable plate through the slider connecting piece, a crank rocker mechanism formed by the clamping plate can drive the movable plate to horizontally reciprocate above the workbench, and when the movable plate horizontally moves, the clamping plate can synchronously rotate under the cooperation of the gear rotating mechanism, so that the reagent tube can be shaken during shaking, the mixed oscillation of the measured reagent is realized, the mixing effect is uniform, and the efficiency is high.
Drawings
Fig. 1 is a structural diagram of the present invention.
Fig. 2 is a structural view of the connecting rod of the present invention.
Fig. 3 is a structural diagram of the movable plate of the present invention.
Fig. 4 is a structural diagram of the driving motor of the present invention.
Wherein: 1. a work table; 2. a toothed plate; 3. a support; 4. teeth; 5. a guide rail; 6. a connecting rod; 7. a movable plate; 8. installing a clamping plate; 9. a test tube rack; 10. a transmission gear; 11. a guide groove; 12. installing a shaft; 13. a chute; 14. a slider; 15. a roller; 16. a supporting seat; 17. a rubber gasket; 18. the motor is driven.
Detailed Description
In order to deepen the understanding of the present invention, the following embodiments are combined to further detail the present invention, and the present embodiment is only used to explain the present invention, and does not constitute the limitation of the protection scope of the present invention.
According to the drawings of fig. 1, 2, 3 and 4, the embodiment provides an oscillating and mixing device for preparing a D-dimer measuring reagent, which comprises a workbench 1 and a guide mechanism, wherein two guide rails 5 are arranged at the upper end of the workbench 1, a movable plate 7 is arranged between the two guide rails 5, and the movable plate 7 is arranged above the workbench 1 and connected with a rocker assembly arranged at the center of the workbench 1;
a clamping plate 8 is arranged at the upper end of the movable plate 7, the clamping plate 8 is rotatably connected with the movable plate 7 and matched with a gear rotating mechanism arranged between the movable plate 7 and the clamping plate 8, and a test tube rack 9 is assembled at the upper end of the clamping plate 8; the rocker component is connected with the movable plate 7 to form a crank rocker mechanism which is used for controlling the movable plate 7 to horizontally reciprocate above the workbench 1, and the movable plate 7 rocks the reagent tubes assembled on the test tube rack 9 in the reciprocating movement. When the test tube rack is shaken, the gear swing mechanism can drive the test tube rack 9 to rotate on the upper end of the movable plate 7, so that the reagent tube is shaken during shaking, mixing oscillation of the D-dimer determination reagent is realized, the mixing effect is uniform, and the efficiency is high.
The guide mechanism comprises a horizontal guide piece and a sliding block connecting piece, the horizontal guide piece is arranged at the matching position of the two ends of the movable plate 7 and the guide rail 5, and the sliding block connecting piece is arranged at the matching position of the rocker assembly and the lower end of the movable plate 7. The guide rails 5 at both ends of the movable plate 7 limit the movable plate 7 through horizontal guide members, so that the movable plate 7 horizontally moves along the guide rails 5, and the slider connecting member at the lower end of the movable plate 7 plays a role in movable guiding and connecting, so that the movable plate 7 horizontally reciprocates when the rocker assembly rotates.
Specifically, the rocker assembly comprises a connecting rod 6 and a driving motor 18, the connecting rod 6 is mounted at the upper end of the workbench 1, one end of the connecting rod 6 is fixedly connected with the top end of a rotating shaft arranged at the center of the workbench 1, and the other end of the connecting rod 6 is arranged below the movable plate 7 and is movably connected with the movable plate 7 through a slider connecting piece;
the driving motor 18 is arranged at the lower end of the workbench 1, and the output end of the driving motor 18 is fixedly connected with the bottom end of the rotating shaft. The rotating shaft penetrates through the workbench 1 and is rotatably connected with the workbench 1. When the driving motor 18 is started, the connecting rod 6 is driven by the rotating shaft to rotate around the center, the other end of the connecting rod 6 is connected with the movable plate 7 through the horizontal guide piece, the movable plate 7 is pushed when the connecting rod moves, the rotating motion of the connecting rod 6 is converted into the reciprocating horizontal motion of the movable plate 7 under the limitation of the guide rail 5, and then the test tube rack 9 is efficiently shaken.
Specifically, the gear swing machine comprises a mounting shaft 12 and a toothed plate 2, the top end of the mounting shaft 12 is fixed at the center of the lower end face of the clamping plate 8, the top end of the mounting shaft 12 is rotatably connected with the upper end of the movable plate 7, and a transmission gear 10 is sleeved outside the shaft body of the mounting shaft 12;
the toothed plate 2 is arranged on one side of the transmission gear 10, teeth 4 matched with the transmission gear 10 are formed in the toothed plate 2, and two ends of the toothed plate 2 are fixedly connected with the support 3 arranged at the upper end of the workbench 1. The gear rotating mechanism works only when the movable plate 7 acts, and shakes the reagent tubes assembled on the test tube rack 9 by controlling the test tube rack 9 to rotate. During operation, the movable plate 7 moves horizontally above the workbench 1, the transmission gear 10 assembled at the upper end of the movable plate 7 is meshed with the teeth 4 on the toothed plate 2 to drive the mounting shaft 12 to rotate, the mounting shaft 12 drives the test tube rack 9 to rotate, when the transmission gear 10 moves to the end of the teeth 4, the movable plate 7 returns reversely, and the transmission gear 10 continues to be matched with the teeth 4, but the rotating direction of the transmission gear changes.
It should be noted that, a space is left between the upper end and the lower end of the toothed plate 2 and between the movable plate 7 and the clamping plate 8, so as to prevent the movable plate 7 and the clamping plate 8 from generating friction with the toothed plate 2 during the movement, and the length of the toothed plate 2 should also be greater than the horizontal movement path of one reciprocating movement of the movable plate 7.
More specifically, the horizontal guide member includes rollers 15 provided at both ends of the movable plate 7, and the rollers 15 are disposed in the guide grooves 11 formed at the side of the guide rail 5 facing the movable plate 7 and are in rolling engagement with the guide grooves 11. When the link 6 pushes the movable plate 7, the guide grooves 11 formed at both ends of the movable plate 7 roll along the rollers 15. Compared with sliding fit, the roller 15 is matched with the guide groove 11, sliding friction can be replaced by rolling friction, friction resistance between the guide rail 5 and the movable plate 7 can be further reduced, and the service life between the movable plate 7 and the guide groove 11 can be prolonged.
The sliding block connecting piece comprises a sliding groove 13 arranged at the lower end of the movable plate 7, a sliding block 14 is arranged in the sliding groove 13, the sliding block 14 is in sliding fit with the sliding groove 13, and the bottom end of the sliding block 14 is hinged with one end, below the movable plate 7, of the connecting rod 6. And the sliding blocks 14 are arranged in the sliding grooves 13 and used for connecting the connecting rods 6, when the connecting rods 6 rotate, the sliding blocks 14 connected with the connecting rods 6 in a rotating mode slide along the sliding grooves 13 and push the movable plate 7 through matching with the sliding grooves 13, so that the movable plate 7 horizontally reciprocates above the workbench 1, and the guide rails 5 positioned on two sides of the movable plate 7 guide the movable plate 7 through horizontal guide pieces.
More specifically, 1 lower extreme of workstation is equipped with two supporting seats 16, and two supporting seats 16 symmetry set up in driving motor 18 both sides and with workstation 1 fixed connection, and the terminal surface is provided with rubber gasket 17 under the supporting seat 16. Two supporting seats 16 set up the lower extreme at workstation 1 for support workstation 1, rubber gasket 17's setting, be used for reinforcing the frictional force between supporting seat 16 and the place the platform, improve the stability of during operation, for making supporting seat 16 carry out effectual support to workstation 1, two supporting seats 16 should set up the border position in workstation 1 both sides.
According to the vibrating and mixing device for preparing the D-dimer measuring reagent, on the basis of a traditional vibrating and mixing device, the movable plate 7 is installed at the upper end of the workbench 1, the test tube rack 9 is installed at the upper end of the clamping plate 8, the lower end of the clamping plate 8 is rotatably connected with the upper end of the movable plate 7, a rocker assembly at the upper end of the workbench 1 is connected with the movable plate 7 through a slider connecting piece, so that a crank rocker mechanism is formed, the movable plate 7 can be driven to horizontally reciprocate above the workbench 1, when the movable plate 7 horizontally acts, the clamping plate 8 can synchronously rotate on the upper end of the movable plate 7 under the cooperation of the gear rotating mechanism, a reagent tube can shake during shaking, mixed oscillation of the measuring reagent is achieved, the mixing effect is uniform, and the efficiency is high.
The foregoing illustrates and describes the general principles, features and advantages of the present invention. It will be understood by those skilled in the art that the present invention is not limited to the above embodiments, and that the foregoing embodiments and descriptions are provided only to illustrate the principles of the present invention without departing from the spirit and scope of the present invention. The scope of the invention is defined by the appended claims and equivalents thereof.

Claims (6)

1. A vibration mixing device for preparing a D-dimer measuring reagent comprises a workbench (1) and a guide mechanism, and is characterized in that two guide rails (5) are arranged at the upper end of the workbench (1), a movable plate (7) is arranged between the two guide rails (5), and the movable plate (7) is arranged above the workbench (1) and connected with a rocker assembly arranged at the center of the workbench (1);
a clamping plate (8) is arranged at the upper end of the movable plate (7), the clamping plate (8) is rotatably connected with the movable plate (7) and matched with a gear rotating mechanism arranged between the movable plate (7) and the clamping plate (8), and a test tube rack (9) is assembled at the upper end of the clamping plate (8);
the guide mechanism comprises a horizontal guide piece and a sliding block connecting piece, the horizontal guide piece is arranged at the matching position of the two ends of the movable plate (7) and the guide rail (5), and the sliding block connecting piece is arranged at the matching position of the rocker assembly and the lower end of the movable plate (7).
2. The oscillating mixing device for preparing a D-dimer measuring reagent according to claim 1, wherein: the rocker assembly comprises a connecting rod (6) and a driving motor (18), the connecting rod (6) is installed at the upper end of the workbench (1), one end of the connecting rod (6) is fixedly connected with the top end of a rotating shaft arranged at the center of the workbench (1), and the other end of the connecting rod (6) is arranged below the movable plate (7) and is movably connected with the movable plate (7) through a sliding block connecting piece;
the driving motor (18) is installed at the lower end of the workbench (1), and the output end of the driving motor (18) is fixedly connected with the bottom end of the rotating shaft.
3. The oscillating mixing device for preparing a D-dimer measuring reagent according to claim 1, wherein: the gear rotating machine comprises an installation shaft (12) and a toothed plate (2), the top end of the installation shaft (12) is fixed at the center of the lower end face of the clamping plate (8), the top end of the installation shaft (12) is rotatably connected with the upper end of the movable plate (7), and a transmission gear (10) is sleeved outside the shaft body of the installation shaft (12);
drive gear (10) one side is arranged in pinion rack (2), set up tooth (4) with drive gear (10) matched with on pinion rack (2), pinion rack (2) both ends with establish support (3) fixed connection in workstation (1) upper end.
4. The shaking mixing device for preparing a D-dimer measuring reagent according to claim 1, wherein: the horizontal guide piece comprises idler wheels (15) arranged at two ends of the movable plate (7), and the idler wheels (15) are arranged in guide grooves (11) formed in one side, facing the movable plate (7), of the guide rail (5) and are in rolling fit with the guide grooves (11).
5. The oscillating mixing device for preparing a D-dimer measuring reagent according to claim 2, wherein: the sliding block connecting piece comprises a sliding groove (13) formed in the lower end of the movable plate (7), a sliding block (14) is arranged in the sliding groove (13), the sliding block (14) is in sliding fit with the sliding groove (13), and the bottom end of the sliding block (14) is hinged to one end, located below the movable plate (7), of the connecting rod (6).
6. The oscillating mixing device for preparing a D-dimer measuring reagent according to claim 2, wherein: workstation (1) lower extreme is equipped with two supporting seats (16), two supporting seat (16) symmetry set up in the both sides of driving motor (18) and with workstation (1) fixed connection, the terminal surface is provided with rubber gasket (17) under supporting seat (16).
CN202222392662.0U 2022-09-08 2022-09-08 D-dimer assay reagent preparation is with shaking mixing arrangement Active CN218530672U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202222392662.0U CN218530672U (en) 2022-09-08 2022-09-08 D-dimer assay reagent preparation is with shaking mixing arrangement

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202222392662.0U CN218530672U (en) 2022-09-08 2022-09-08 D-dimer assay reagent preparation is with shaking mixing arrangement

Publications (1)

Publication Number Publication Date
CN218530672U true CN218530672U (en) 2023-02-28

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ID=85272240

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202222392662.0U Active CN218530672U (en) 2022-09-08 2022-09-08 D-dimer assay reagent preparation is with shaking mixing arrangement

Country Status (1)

Country Link
CN (1) CN218530672U (en)

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