CN217973236U - Dropper for embryo culture - Google Patents
Dropper for embryo culture Download PDFInfo
- Publication number
- CN217973236U CN217973236U CN202221687080.9U CN202221687080U CN217973236U CN 217973236 U CN217973236 U CN 217973236U CN 202221687080 U CN202221687080 U CN 202221687080U CN 217973236 U CN217973236 U CN 217973236U
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- China
- Prior art keywords
- embryo culture
- dropper
- pipette
- housing
- inverted cone
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- 210000001161 mammalian embryo Anatomy 0.000 title claims abstract description 37
- 239000007788 liquid Substances 0.000 claims abstract description 19
- 239000000463 material Substances 0.000 claims description 9
- 230000002209 hydrophobic effect Effects 0.000 claims description 7
- 238000012546 transfer Methods 0.000 abstract description 9
- 239000003153 chemical reaction reagent Substances 0.000 description 4
- 239000000443 aerosol Substances 0.000 description 3
- 230000036512 infertility Effects 0.000 description 3
- 238000004806 packaging method and process Methods 0.000 description 3
- 238000012360 testing method Methods 0.000 description 3
- 238000010586 diagram Methods 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 238000005213 imbibition Methods 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 230000002093 peripheral effect Effects 0.000 description 2
- 238000011161 development Methods 0.000 description 1
- 210000002257 embryonic structure Anatomy 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000002349 favourable effect Effects 0.000 description 1
- 239000001963 growth medium Substances 0.000 description 1
- 238000003780 insertion Methods 0.000 description 1
- 230000037431 insertion Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000035515 penetration Effects 0.000 description 1
- 230000007704 transition Effects 0.000 description 1
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- Apparatus Associated With Microorganisms And Enzymes (AREA)
Abstract
There is provided a dropper useful for embryo culture, comprising: a tube body having a liquid-absorbing end and a connecting end; the connecting part is arranged at the connecting end and comprises an annular body and a boss arranged on the periphery of the annular body, and the boss can be screwed into a spiral slideway arranged on the pipettor and is connected with the pipettor; the filter element is arranged in the pipe body and is positioned at the upper part of the pipe body; and the shell is detachably sleeved on the pipe body. Can be matched with a pipettor to realize the sterile and/or high-efficiency transfer of embryo culture solution or oil seal liquid for assisting reproduction.
Description
Technical Field
The utility model relates to an auxiliary reproduction field especially relates to a burette that can be used to embryo culture.
Background
In recent years, the more people who assist in reproduction, the more and more rapid development and application of assisted reproduction technology are achieved.
For assisted reproduction medical institutions, a large number of different assisted reproduction populations are faced each day, and multiple embryos need to be provided for the physician and user to cultivate and select in order to pick out the optimal embryo for further cultivation. For embryo culture, transfer of culture solution and transfer of oil seal are often involved, and how to transfer aseptically, automatically and/or efficiently is an urgent problem to be solved.
Therefore, there is a need to develop a dropper for embryo culture that can solve one or more of the above-mentioned problems.
SUMMERY OF THE UTILITY MODEL
In order to solve at least one technical problem, according to an aspect of the present invention, there is provided a dropper for embryo culture, comprising:
a tube body having a liquid-absorbing end and a connecting end;
the connecting part is arranged at the connecting end and comprises an annular body and a boss arranged on the periphery of the annular body, and the boss can be screwed into a spiral slideway arranged on the pipettor and is connected with the pipettor;
the filter element is arranged in the pipe body and is positioned at the upper part of the pipe body; and
the shell is detachably sleeved on the pipe body.
According to yet another aspect of the invention, the upper end of the housing abuts the annular body and the tube body is sealingly received within the housing.
According to the utility model discloses in another aspect, the upper end of shell is provided with annular step, annular step butt the annular body.
According to the utility model discloses in another aspect, the boss be two or more and the interval set up in the annular body periphery, the boss is connected with the pipettor gas tightness.
According to yet another aspect of the present invention, the outer periphery of the housing is disposed in the raised hand-held portion.
According to the utility model discloses in another aspect, body and connecting portion integrated into one piece, just the burette that can be used to embryo culture is disposable burette.
According to the utility model discloses in another aspect, the body is including the first portion, second portion and the third portion that connect gradually, the first portion is the back taper portion, and the second portion is back taper portion, and the third portion is the cylinder portion, filter core set up in the cylinder portion, the top of back taper portion forms the imbibition end, connecting portion set up in on the cylinder portion.
According to another aspect of the present invention, the housing is integrally formed, and the pipe body is made of a hydrophobic material.
According to the utility model discloses in another aspect, the body is including the inverted cone portion, back taper barrel portion, first cylinder portion and the second cylinder portion that connect gradually, the top of inverted cone portion forms the imbibition end, connecting portion set up in on the second cylinder portion, the diameter of first cylinder portion is greater than the diameter of second cylinder portion, the body is made by oleophobic material.
According to still another aspect of the present invention, the outer periphery of the second cylindrical portion is provided with a stepped portion.
The utility model discloses can obtain following one or more technological effect:
the independent packaging (detachable) shell can ensure that the surface of the tube body is not polluted when the dropper is loaded, thereby realizing the sterility;
the embryo culture solution or oil seal liquid can be transferred efficiently;
the automatic transfer of embryo culture solution or oil seal liquid can be realized by matching with a liquid transfer device;
the use of the hydrophobic or oleophobic material can save the use of embryo culture solution or oil seal liquid;
the lengthened dropper (sucker) can conveniently extend into the bottom of a long or narrow container, such as a test tube, a reagent bottle, a flask and other containers;
the filter element can prevent liquid from accidentally splashing into the pipette and reduce aerosol from permeating into a pipette tip cone in the pipetting process;
the connecting part (interface) can ensure the tight connection for a long time, and is convenient for loading, disassembling and discarding the dropper.
Drawings
The present invention will be described in further detail with reference to the accompanying drawings and specific embodiments.
FIG. 1 is a schematic structural view of a dropper (without a case) for embryo culture according to a first preferred embodiment of the present invention.
FIG. 2 is a schematic view of the dropper (after being sheathed with a sheath) of FIG. 1 that can be used for embryo culture.
FIG. 3 is a schematic diagram of the housing of the pipette of FIG. 2 that can be used for embryo culture.
Fig. 4 is a schematic structural view of a dropper (without a case) for embryo culture according to a second preferred embodiment of the present invention.
FIG. 5 is a schematic view of the dropper (after being sheathed with a sheath) of FIG. 4 that can be used for embryo culture.
FIG. 6 is a schematic diagram of the housing of the pipette of FIG. 5 that can be used for embryo culture.
Detailed Description
The best mode of the present invention will be described in detail with reference to the accompanying drawings, wherein the detailed description is to be regarded as illustrative in nature and not as restrictive, and various changes and modifications may be made without departing from the spirit and scope of the present invention.
Example 1
According to a preferred embodiment of the present invention, referring to fig. 1 to 6, there is provided a dropper for embryo culture, comprising:
the tube body 1 is provided with a liquid suction end and a connecting end;
the connecting part 2 is arranged at the connecting end and comprises an annular body and a boss 21 arranged on the periphery of the annular body, and the boss 21 can be screwed into a spiral slideway arranged on the pipettor and is connected with the pipettor;
the filter element 3 is arranged in the pipe body 1 and is positioned at the upper part of the pipe body 1; and
the shell is detachably sleeved on the pipe body 1.
It will be appreciated that the pipette is provided with an internal bore which receives and nests the connection 2, and that the helical slide is provided in the peripheral wall of the internal bore.
Preferably, a separate packaging housing is provided to ensure that the surface of the pipette tip is not contaminated when the pipette tip is loaded.
Preferably, the inner surface of the individual casing has local features which are in transition fit with the outer surface of the suction head, so that the casing can be sleeved and fixed outside the suction head and can be removed without damaging the suction head.
Preferably, the elongated tips are adapted to facilitate insertion into the bottom of long or narrow containers, such as test tubes, reagent bottles, flasks and other containers.
Advantageously, the filter element prevents accidental splashing of liquid into the interior of the pipette and reduces the penetration of aerosol onto the pipette tip cone during pipetting.
According to a further preferred embodiment of the invention, see fig. 2, the upper end of the housing abuts the annular body and the pipe body 1 is sealingly received in the housing. Thereby a thorough sterility protection can be achieved.
According to a further preferred embodiment of the invention, see fig. 2-3, the upper end of the housing is provided with an annular step abutting the annular body. The annular step facilitates nesting and/or removal of the housing.
According to another preferred embodiment of the present invention, referring to fig. 1, the number of the bosses is two or more and are disposed at the periphery of the ring body at intervals, and the bosses are connected with the pipettor in an airtight manner.
According to a further preferred embodiment of the invention, the outer circumference of the housing is arranged in a protruding handhold portion (not shown). The hand-held portion may further facilitate the removal of the housing.
According to another preferred embodiment of the present invention, the tube body 1 and the connecting portion 2 are integrally formed, and the dropper usable for embryo culture is a disposable dropper. The dropper is designed to be detached, replaced and discarded after being used for a preset time, which is favorable for providing a stable environment for embryo culture and avoids introducing pollution.
According to another preferred embodiment of the present invention, referring to fig. 1, the pipe body 1 includes a first portion, a second portion and a third portion connected in sequence, the first portion is an inverted cone portion 11, the second portion is an inverted cone portion 12, the third portion is a cylindrical portion 13, the filter element 3 is disposed on the cylindrical portion, the top end of the inverted cone portion forms the liquid suction end, and the connection portion 2 is disposed on the cylindrical portion. The tube is designed for the aspiration and transfer of culture medium, preferably in a volume of about 1000 microliters.
According to another preferred embodiment of the present invention, the housing is integrally formed, and the pipe body 1 is made of hydrophobic material. Advantageously, the hydrophobic material renders the pipette hydrophobic, greatly reducing the loss of sample due to adhesion, which has the advantage of improved pipetting performance and saves expensive reagents.
According to another preferred embodiment of the present invention, referring to fig. 4, the pipe body 1 includes an inverted cone portion 11, an inverted cone portion 12, a (first) cylindrical portion 13, and a second cylindrical portion 15 connected in series, the top end of the inverted cone portion forms the liquid suction end, the connection portion 2 is provided on the second cylindrical portion, the diameter of the first cylindrical portion 13 is larger than the diameter of the second cylindrical portion 15, and the pipe body 1 is made of an oleophobic material. The tube is designed to suck and transfer oil (for oil seal).
According to a further preferred embodiment of the present invention, the outer periphery of the second cylindrical portion is provided with a step portion 14.
When the device is used, the dropper is screwed into the spiral slideway arranged on the peripheral wall of the inner hole of the pipette, then the shell is downwards removed, the pipette moves and applies negative pressure to enable the dropper to suck target liquid, the dropper moves to a target position, and positive pressure is applied to enable the liquid to be dripped into an embryo culture dish. When the dropper needs to be discarded, the dropper is unscrewed and then a new dropper is loaded again.
The utility model discloses can obtain following one or more technological effect:
the independent packaging (detachable) shell can ensure that the surface of the tube body is not polluted when the dropper is loaded, and the sterility is realized;
the embryo culture solution or oil seal liquid can be transferred efficiently;
the embryo culture solution or oil seal liquid can be automatically transferred by matching with a liquid transfer device;
the use of the hydrophobic or oleophobic material can save the use of embryo culture solution or oil seal liquid;
the lengthened dropper (sucker) can conveniently extend into the bottom of a long or narrow container, such as a test tube, a reagent bottle, a flask and other containers;
the filter element can prevent liquid from accidentally splashing into the pipette and reduce aerosol from permeating into a pipette tip cone in the pipetting process;
the connecting part (interface) can ensure the tight connection for a long time, and is convenient for loading, disassembling and discarding the dropper.
It will be understood by those skilled in the art that the present invention is not limited to the above embodiments, and that the foregoing embodiments and descriptions are provided only to illustrate the principles of the present invention without departing from the spirit and scope of the present invention. The scope of the invention is defined by the appended claims and equivalents thereof.
Claims (10)
1. A burette for embryo culture, comprising:
a tube body having a liquid-absorbing end and a connecting end;
the connecting part is arranged at the connecting end and comprises an annular body and a boss arranged on the periphery of the annular body, and the boss can be screwed into a spiral slide arranged on the pipettor and is connected with the pipettor;
the filter element is arranged in the pipe body and is positioned at the upper part of the pipe body; and
the shell is detachably sleeved on the pipe body.
2. The pipette useful for embryo culture as claimed in claim 1, wherein the upper end of the housing abuts the annular body and the tube is sealingly housed within the housing.
3. The pipette useful for embryo culture as claimed in claim 2, wherein the upper end of the housing is provided with an annular step abutting the annular body.
4. The pipette for embryo culture according to claim 3, wherein the number of the bosses is two or more and the bosses are arranged at the periphery of the annular body at intervals, and the bosses are connected with the pipette in an airtight manner.
5. The pipette useful for embryo culture according to claim 4, wherein the outer circumference of the housing is provided to the protruding hand-held portion.
6. The dropper for embryo culture as claimed in claim 5, wherein the tube body and the connecting portion are integrally formed, and the dropper for embryo culture is a disposable dropper.
7. The dropper for embryo culture as claimed in any one of claims 1-6, wherein the tube body comprises a first portion, a second portion and a third portion connected in sequence, the first portion is an inverted cone portion, the second portion is an inverted cone portion, the third portion is a cylinder portion, the filter element is disposed on the cylinder portion, the top end of the inverted cone portion forms the liquid suction end, and the connecting portion is disposed on the cylinder portion.
8. The pipette useful for embryo culture as claimed in claim 7, wherein the housing is integrally formed and the tube body is made of hydrophobic material.
9. The dropper usable for embryo culture according to any one of claims 1 to 6, wherein the tube body comprises an inverted cone portion, a first cylindrical portion and a second cylindrical portion connected in sequence, wherein the top end of the inverted cone portion forms the liquid suction end, the connection portion is disposed on the second cylindrical portion, the diameter of the first cylindrical portion is larger than that of the second cylindrical portion, and the tube body is made of an oleophobic material.
10. The pipette usable for embryo culture according to claim 9, wherein the second cylindrical portion is provided with a stepped portion at the outer periphery thereof.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202221687080.9U CN217973236U (en) | 2022-07-01 | 2022-07-01 | Dropper for embryo culture |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202221687080.9U CN217973236U (en) | 2022-07-01 | 2022-07-01 | Dropper for embryo culture |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN217973236U true CN217973236U (en) | 2022-12-06 |
Family
ID=84275976
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202221687080.9U Active CN217973236U (en) | 2022-07-01 | 2022-07-01 | Dropper for embryo culture |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN217973236U (en) |
-
2022
- 2022-07-01 CN CN202221687080.9U patent/CN217973236U/en active Active
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20240521 Address after: 230000, No. 999 Weiwu Road, Hefei Xinzhan High tech Zone, Hefei City, Anhui Province Patentee after: HEFEI INNOVATION RESEARCH INSTITUTE, BEIHANG University Country or region after: China Address before: Room 102-17, Area C, 1st Floor, 3U Maker Space, Hefei National University Science and Technology Park Entrepreneurship Incubation Center, No. 602 Huangshan Road, High-tech Zone, Hefei City, Anhui Province, 230088 Patentee before: Anhui Aberui Technology Co.,Ltd. Country or region before: China |