CN217817751U - Preparation facilities of exosome freeze-dried powder - Google Patents
Preparation facilities of exosome freeze-dried powder Download PDFInfo
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- CN217817751U CN217817751U CN202221856311.4U CN202221856311U CN217817751U CN 217817751 U CN217817751 U CN 217817751U CN 202221856311 U CN202221856311 U CN 202221856311U CN 217817751 U CN217817751 U CN 217817751U
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- exosome
- freeze
- working plate
- dried powder
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Abstract
The utility model discloses a preparation facilities of exosome freeze-dried powder, wherein, preparation facilities of exosome freeze-dried powder includes the working plate, the upper end fixedly connected with mounting bracket of working plate, the upper end fixedly connected with electric putter of mounting bracket, electric putter's lower extreme fixedly connected with connecting plate, the lower extreme fixedly connected with motor of connecting plate, the output shaft fixedly connected with dwang of motor, the lower extreme fixedly connected with apron of dwang, the lower extreme fixedly connected with a plurality of glass stick of apron, the upper end of working plate is provided with the mixed bottle, the first liquid outlet of lower extreme fixedly connected with of mixed bottle, the lower extreme fixedly connected with filter cartridge of working plate, the inner wall fixedly connected with installation piece of filter cartridge, the inboard sliding connection of installation piece has the fixed block. Through setting up motor, glass stick, dwang, carry out intensive mixing to exosome and freeze-drying agent, improve preparation efficiency.
Description
Technical Field
The utility model relates to an exosome freeze-drying powder preparation technical field, in particular to freeze-drying powder's preparation facilities.
Background
The exosome is formed by cells through a series of regulation processes of endocytosis-fusion-efflux and the like, is actively secreted to the outside of the cells, is a subcellular bilayer membrane vesicle with uniform size and 40-100 nm of molecular diameter, and contains substances such as protein, miRNA, mRNA and the like related to cell sources. Exosomes can directly activate receptor cells through plasma membrane receptors, can also transport proteins, miRNAs and mRNAs even organelles into the receptor cells, and can also carry specific substances contained in the cells in different pathological states, thereby playing an important role in physiology and pathology. The application of exosomes is mainly focused on clinical diagnosis, anti-tumor and cosmetic anti-aging.
The preparation facilities of current exosome freeze-dried powder when using, is not convenient for carry out the intensive mixing with exosome and freeze-drying agent, and then produces the influence to preparation efficiency.
SUMMERY OF THE UTILITY MODEL
In order to realize the above-mentioned purpose, provide exosome freeze-dried powder's preparation facilities includes: the glass tube comprises a working plate, wherein the upper end of the working plate is fixedly connected with an installation frame, the upper end of the installation frame is fixedly connected with an electric push rod, the lower end of the electric push rod is fixedly connected with a connecting plate, the lower end of the connecting plate is fixedly connected with a motor, an output shaft of the motor is fixedly connected with a rotating rod, the lower end of the rotating rod is fixedly connected with a cover plate, and the lower end of the cover plate is fixedly connected with a plurality of glass rods;
the upper end of working plate is provided with the mixing flask, the first liquid outlet of lower extreme fixedly connected with of mixing flask, the lower extreme fixedly connected with filter box of working plate, the inner wall fixedly connected with installation piece of filter box, the inboard sliding connection of installation piece has the fixed block, one side fixedly connected with filter membrane of fixed block, the lower extreme fixedly connected with second liquid outlet of filter box, the upper end of working plate is provided with the freeze dryer.
According to the preparation facilities of exosome freeze-dried powder, the interior diapire fixedly connected with water conservancy diversion piece of mixing bottle.
According to the preparation facilities of exosome freeze-dried powder, the glass stick is provided with three.
According to the preparation facilities of exosome freeze-dried powder, the inside of first liquid outlet is provided with the solenoid valve.
According to the preparation facilities of exosome freeze-dried powder, the preceding terminal surface of filter cartridge is provided with sealed lid, one side fixedly connected with handle of sealed lid.
According to the preparation facilities of exosome freeze-drying powder, the lower extreme fixedly connected with a plurality of support column of working plate, the support column is provided with four.
According to the preparation facilities of exosome freeze-dried powder, the lower extreme fixedly connected with bottom plate of support column.
The utility model discloses a solve one of the technical problem that exists among the prior art at least, provide the preparation facilities of exosome freeze-dried powder, main innovation point:
1. through setting up motor, glass stick, dwang, carry out intensive mixing to exosome and freeze-drying agent, improve preparation efficiency.
2. Through setting up the filter membrane, filter the mixed solution of exosome and freeze-drying agent for the freeze-dried powder quality of preparing is higher.
Additional aspects and advantages of the invention will be set forth in part in the description which follows and, in part, will be obvious from the description, or may be learned by practice of the invention.
Drawings
The present invention will be further described with reference to the accompanying drawings and examples;
fig. 1 is a perspective view of an exosome lyophilized powder preparation device provided by the utility model;
FIG. 2 is a cross-sectional view of the device for preparing exosome lyophilized powder provided by the present invention;
fig. 3 is a schematic structural view of a point a in fig. 2 according to the present invention;
fig. 4 is a front view of the filter cartridge of the device for preparing exosome lyophilized powder provided by the utility model.
Illustration of the drawings:
1. a working plate; 2. a mounting frame; 3. an electric push rod; 4. a connecting plate; 5. a motor; 6. rotating the rod; 7. a glass rod; 8. mixing the bottles; 9. a support column; 10. a cover plate; 11. a flow guide block; 12. an electromagnetic valve; 13. a first liquid outlet; 14. a filter cartridge; 15. a second liquid outlet; 16. mounting blocks; 17. a fixed block; 18. filtering the membrane; 19. a sealing cover; 20. a handle; 21. a freeze dryer; 22. a base plate.
Detailed Description
This section will describe in detail the embodiments of the present invention, preferred embodiments of the present invention are shown in the attached drawings, which are used to supplement the description of the text part of the specification with figures, so that one can intuitively and vividly understand each technical feature and the whole technical solution of the present invention, but they cannot be understood as the limitation of the protection scope of the present invention.
Referring to fig. 1-4, the embodiment of the present invention provides a device for preparing exosome freeze-dried powder, which comprises a working plate 1, wherein the upper end of the working plate 1 is fixedly connected with an installation frame 2, the upper end of the installation frame 2 is fixedly connected with an electric push rod 3, the lower end of the electric push rod 3 is fixedly connected with a connection plate 4, the lower end of the connection plate 4 is fixedly connected with a motor 5, the output shaft of the motor 5 is fixedly connected with a rotating rod 6, the lower end of the rotating rod 6 is fixedly connected with a cover plate 10, the lower end of the cover plate 10 is fixedly connected with a plurality of glass rods 7, and by arranging the motor 5, the glass rods 7 and the rotating rod 6, exosome and freeze-dried agent are fully mixed, so as to improve the preparation efficiency;
the upper end of working plate 1 is provided with mixing flask 8, the first liquid outlet 13 of lower extreme fixedly connected with of mixing flask 8, the lower extreme fixedly connected with filter cartridge 14 of working plate 1, the inner wall fixedly connected with installation piece 16 of filter cartridge 14, the inboard sliding connection of installation piece 16 has fixed block 17, one side fixedly connected with filter membrane 18 of fixed block 17, through setting up filter membrane 18, filter the mixed solution of exosome and freeze-drying agent, the freeze-drying powder quality of feasible preparation is higher, the lower extreme fixedly connected with second liquid outlet 15 of filter cartridge 14, the upper end of working plate 1 is provided with freeze dryer 21, freeze dryer 21 is any one among the prior art.
Interior diapire fixedly connected with water conservancy diversion piece 11 of mixing bottle 8, through setting up water conservancy diversion piece 11, prevent that the mixed liquid of exosome from remaining in mixing bottle 8's bottom, glass stick 7 is provided with threely, the inside of first liquid outlet 13 is provided with solenoid valve 12, the preceding terminal surface of filter box 14 is provided with sealed lid 19, conveniently change filter membrane 18, one side fixedly connected with handle 20 of sealed lid 19, conveniently open sealed lid 19, the lower extreme fixedly connected with a plurality of support column 9 of working plate 1, support column 9 is provided with four, the lower extreme fixedly connected with bottom plate 22 of support column 9.
The working principle is as follows: this preparation facilities of exosome freeze-dried powder, connect external power supply with the device when using, add exosome and freeze-drying agent in the mixing flask 8, start electric putter 3, motor 5, electric putter 3 drives apron 10 and descends, cover mixing flask 8, motor 5 drives dwang 6 and rotates, dwang 6 drives glass stick 7 and rotates, stir the mixture with the freeze-drying agent to exosome, after the mixture is accomplished, open solenoid valve 12, exosome mixed liquid gets into in filter cartridge 14 through first liquid outlet 13, filter through filter membrane 18, flow out through second liquid outlet 15, collect through the container, low temperature refrigeration twenty-four hours after collecting, then freeze-dry twenty-four hours in freeze dryer 21, after freeze-dry, obtain exosome freeze-dried powder.
The embodiments of the present invention have been described in detail with reference to the accompanying drawings, but the present invention is not limited to the above embodiments, and various changes can be made without departing from the spirit of the present invention within the knowledge of those skilled in the art.
Claims (7)
1. Preparation facilities of exosome freeze-dried powder, its characterized in that includes: the glass cleaning device comprises a working plate (1), wherein the upper end of the working plate (1) is fixedly connected with a mounting frame (2), the upper end of the mounting frame (2) is fixedly connected with an electric push rod (3), the lower end of the electric push rod (3) is fixedly connected with a connecting plate (4), the lower end of the connecting plate (4) is fixedly connected with a motor (5), an output shaft of the motor (5) is fixedly connected with a rotating rod (6), the lower end of the rotating rod (6) is fixedly connected with a cover plate (10), and the lower end of the cover plate (10) is fixedly connected with a plurality of glass rods (7);
the upper end of working plate (1) is provided with mixing bottle (8), the first liquid outlet of lower extreme fixedly connected with (13) of mixing bottle (8), the lower extreme fixedly connected with filter cartridge (14) of working plate (1), the inner wall fixedly connected with installation piece (16) of filter cartridge (14), the inboard sliding connection of installation piece (16) has fixed block (17), one side fixedly connected with filter membrane (18) of fixed block (17), the lower extreme fixedly connected with second liquid outlet (15) of filter cartridge (14), the upper end of working plate (1) is provided with freeze dryer (21).
2. A preparation device of exosome lyophilized powder according to claim 1, wherein a flow guide block (11) is fixedly connected to the inner bottom wall of the mixing bottle (8).
3. A device for preparing exosome freeze-dried powder according to claim 1, characterized in that the glass rod (7) is provided with three.
4. A preparation apparatus for exosome freeze-dried powder according to claim 1, wherein an electromagnetic valve (12) is arranged inside the first liquid outlet (13).
5. A preparation apparatus for exosome lyophilized powder according to claim 1, wherein a sealing cover (19) is arranged on the front end face of the filter cartridge (14), and a handle (20) is fixedly connected to one side of the sealing cover (19).
6. A preparation apparatus of exosome freeze-dried powder according to claim 1, characterized in that the lower end of the working plate (1) is fixedly connected with a plurality of support columns (9), and the number of the support columns (9) is four.
7. A preparation device of exosome freeze-dried powder according to claim 6, characterized in that the lower end of the support column (9) is fixedly connected with a bottom plate (22).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202221856311.4U CN217817751U (en) | 2022-07-19 | 2022-07-19 | Preparation facilities of exosome freeze-dried powder |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202221856311.4U CN217817751U (en) | 2022-07-19 | 2022-07-19 | Preparation facilities of exosome freeze-dried powder |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN217817751U true CN217817751U (en) | 2022-11-15 |
Family
ID=83966129
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202221856311.4U Active CN217817751U (en) | 2022-07-19 | 2022-07-19 | Preparation facilities of exosome freeze-dried powder |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN217817751U (en) |
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2022
- 2022-07-19 CN CN202221856311.4U patent/CN217817751U/en active Active
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