CN217786910U - Luminous immunity analyzer - Google Patents

Luminous immunity analyzer Download PDF

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Publication number
CN217786910U
CN217786910U CN202221279519.4U CN202221279519U CN217786910U CN 217786910 U CN217786910 U CN 217786910U CN 202221279519 U CN202221279519 U CN 202221279519U CN 217786910 U CN217786910 U CN 217786910U
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China
Prior art keywords
module
sample
reagent
tray
assembly
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CN202221279519.4U
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Chinese (zh)
Inventor
孟杰
余波
童明
邹杨建
陈颜豪
战乃乾
吴和晋
蔡坤鹏
施志欣
段学欣
胡亚军
赵逸祥
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Zhejiang Pushkang Biotechnology Co ltd
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Zhejiang Pushkang Biotechnology Co ltd
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Priority to CN202221279519.4U priority Critical patent/CN217786910U/en
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Abstract

The application discloses a luminescence immunoassay appearance. The luminescence immunoassay analyzer comprises a frame, a reagent sample module, a detection module, a sample adding module, a liquid path module and an electric control module. The frame comprises a bottom plate and a frame body; the reagent sample module is arranged on the bottom plate and comprises a rotatably arranged reagent loading disc, and a reagent box positioning part, a sample tube positioning part and a substrate tube positioning part are arranged on the reagent loading disc; the detection module comprises a tray frame, a tray, a PMT assembly and a needle washing pool; the sample adding module comprises a guide rail assembly and a sample adding needle assembly, and the sample adding needle assembly is slidably arranged on the guide rail assembly and can move back and forth between the reagent sample module and the detection module; the liquid path module is arranged on the bottom plate and is positioned behind the reagent sample module; the electric control module is arranged on the bottom plate and is positioned behind the detection module. The problem of the luminous immunoassay appearance among the prior art's volume comparison, be not convenient for transport and use can be solved to this application.

Description

Luminous immunity analyzer
Technical Field
The application relates to the technical field of medical equipment, in particular to a luminous immunoassay analyzer.
Background
A luminescence immunoassay instrument is an analytical instrument that combines a luminescence reaction with an immunoreaction to detect an antigen or an antibody. It adopts the micro-multiplication technology, and has good sensitivity and specificity; the detection range is very wide, and the detection range can be detected from traditional proteins, hormones, enzymes to medicines. At present, the structure of the luminescence immunoassay analyzer is comparatively dispersed, and the volume of the whole luminescence immunoassay analyzer is comparatively large, so that the luminescence immunoassay analyzer is inconvenient to carry and use.
SUMMERY OF THE UTILITY MODEL
The main objective of this application provides a luminous immunoassay appearance to solve the volume comparison of the luminous immunoassay appearance among the prior art, the problem of be not convenient for transport and use.
According to an aspect of an embodiment of the present application, there is provided a luminescence immunoassay analyzer including:
the rack comprises a bottom plate and a rack body supported and arranged on the bottom plate;
a reagent sample module disposed on the bottom plate, the reagent sample module including a rotatably disposed reagent loading tray, the reagent loading tray being provided with a reagent cartridge positioning portion, a sample tube positioning portion, and a substrate tube positioning portion;
the detection module is arranged on the bottom plate and is arranged side by side with the reagent sample module, the detection module comprises a tray frame, a tray, a PMT assembly and a needle washing pool, the tray is rotatably arranged on the tray frame, the PMT assembly is arranged at the bottom of the tray frame, and the needle washing pool is arranged at the side edge of the tray frame;
the sample adding module comprises a guide rail assembly and a sample adding needle assembly, the guide rail assembly is arranged on the frame body, and the sample adding needle assembly is slidably arranged on the guide rail assembly so as to move back and forth between the reagent sample module and the detection module;
the liquid path module is arranged on the bottom plate and is positioned behind the reagent sample module so as to at least convey cleaning liquid to the needle washing pool and the sample injection needle assembly; and
and the electronic control module is arranged on the bottom plate and positioned behind the detection module so as to control the reagent sample module, the detection module, the sample adding module and the liquid path module at least.
Further, the reagent sample module further comprises:
the heat dissipation assembly is arranged on the bottom plate, and the reagent loading plate is rotatably arranged on the heat dissipation assembly.
Further, the reagent loading tray has an inner ring tray and an outer ring tray provided on the outer periphery of the inner ring tray, a plurality of the reagent cartridge positioning portions are provided at intervals in the circumferential direction of the inner ring tray, and a plurality of the sample tube positioning portions and a plurality of the substrate tube positioning portions are provided at intervals on the outer periphery of the outer ring tray.
Furthermore, the reagent sample module further comprises a code scanning assembly and a first motor, wherein the code scanning assembly is arranged on the heat dissipation assembly and located on the outer side of the reagent loading disc, and the first motor is in driving connection with the reagent loading disc to drive the reagent loading disc to rotate.
Further, detection module still includes the apron, the apron can set up with overturning in the tray frame is in order to be used for with the tray covers or opens, be provided with the application of sample hole on the apron.
Further, the detection module further comprises a light-tight assembly for sealing at least the well and the PMT assembly.
Further, the periphery of tray frame sets up the light screen, the bottom of tray frame is provided with the second motor, the second motor with the tray drive is connected in order to drive the tray rotates.
Further, the needle washing pool is located between the tray frame and the reagent sample module, and a liquid level sensor is arranged at the bottom of the needle washing pool.
Further, the liquid path module includes:
a mounting plate mounted to the base plate;
the cleaning liquid container is connected with a first plate penetrating quick-connection plug arranged on the mounting plate;
the waste liquid container is connected with a second plate-penetrating quick-plug connector arranged on the mounting plate;
the plunger pump is communicated with the first plate penetrating quick-connection connector and is used for pumping cleaning liquid to the sample injection needle assembly;
the peristaltic pump is communicated with the first plate penetrating quick-connection connector and is used for pumping cleaning liquid to the needle washing pool;
the waste liquid diaphragm pump is communicated with the second plate penetrating quick-connection plug so as to pump the condensate at the reagent sample module to the waste liquid container;
and the needle washing diaphragm pump is communicated with the second plate penetrating quick-connection connector to pump the waste liquid in the needle washing pool to the waste liquid container.
The third motor is in driving connection with the sampling needle assembly to drive the sampling needle assembly to reciprocate horizontally, and the fourth motor is in driving connection with the sampling needle assembly to drive the sampling needle assembly to reciprocate vertically.
Compared with the prior art, the technical scheme of the application has at least the following technical effects:
the utility model provides a luminous immunoassay appearance adopts the modularized design, and whole structure includes the frame and sets up reagent sample module, detection module, application of sample module, liquid circuit module and the automatically controlled module in the frame, and the compact structure nature of whole luminous immunoassay appearance can be improved to the mode of modularized design, and then can reduce whole luminous immunoassay appearance's whole volume, convenient to use and transport more. Meanwhile, the modular design mode is adopted, and the luminous immunoassay analyzer is convenient to assemble and overhaul.
Drawings
The accompanying drawings, which are included to provide a further understanding of the application and are incorporated in and constitute a part of this application, illustrate embodiment(s) of the application and together with the description serve to explain the application and not to limit the application. In the drawings:
FIG. 1 is a schematic structural diagram of a luminescence immunoassay analyzer disclosed in an embodiment of the present application;
FIG. 2 is a schematic structural view of a luminescence immunoassay analyzer disclosed in an embodiment of the present application with a partial housing removed;
FIG. 3 is a schematic structural diagram of a rack disclosed in an embodiment of the present application;
FIG. 4 is a schematic diagram of a reagent sample module disclosed in an embodiment of the present application in a first viewing angle;
FIG. 5 is a schematic diagram of a reagent sample module disclosed in an embodiment of the present application, shown from a second perspective;
fig. 6 is a schematic structural diagram of a detection module disclosed in an embodiment of the present application when the detection module is at a first viewing angle;
fig. 7 is a partial structural schematic view of a detection module disclosed in an embodiment of the present application when the detection module is at a second viewing angle;
fig. 8 is a schematic structural diagram of a detection module disclosed in an embodiment of the present application at a third viewing angle;
FIG. 9 is a cross-sectional view of a portion of a needle wash basin disclosed in an embodiment of the present application;
FIG. 10 is an enlarged view of the area M in FIG. 9;
fig. 11 is a schematic structural diagram of a liquid path module disclosed in an embodiment of the present application at a first viewing angle;
fig. 12 is a schematic structural diagram of a liquid path module disclosed in an embodiment of the present application at a second viewing angle;
fig. 13 is a schematic structural view of a sample application module disclosed in an embodiment of the present application when the sample application module is at a first viewing angle;
fig. 14 is a schematic structural view of a sample application module disclosed in an embodiment of the present application at a second viewing angle;
fig. 15 is a schematic structural diagram of an electronic control module disclosed in the embodiment of the present application.
Wherein the figures include the following reference numerals:
10. a frame; 11. a base plate; 111. damping feet; 112. an air inlet screen plate; 12. a frame body; 13. an upper cover; 14. a printer; 15. a display screen; 16. a status indicator light; 20. a reagent sample module; 21. a reagent loading tray; 211. a kit positioning part; 212. a sample tube positioning section; 213. a substrate tube positioning portion; 2101. an inner ring disc; 2102. an outer ring disc; 22. a heat dissipating component; 221. a radiating air duct metal plate; 222. a heat sink; 223. a fan; 23. a code scanning component; 24. a first motor; 30. a detection module; 31. a tray rack; 311. a visor; 32. a tray; 33. a PMT component; 34. a needle washing pool; 341. a liquid level sensor; 35. a cover plate; 351. a sample application hole; 352. a door magnetic switch; 361. a tubular electromagnet; 362. a first light-tight member; 363. a lifting magnet; 364. a second light-tight member; 37. a second motor; 40. a sample adding module; 41. a guide rail assembly; 411. a horizontal guide rail; 412. a vertical guide rail; 42. a sample injection needle assembly; 421. a fixed block; 422. a sample adding needle; 43. a third motor; 44. a fourth motor; 50. a liquid path module; 51. mounting a plate; 52. a three-way joint; 53. an electromagnetic valve; 54. a plunger pump; 55. a peristaltic pump; 56. a waste liquid diaphragm pump; 57. a needle washing diaphragm pump; 58. a first board-through quick connector; 59. a second board-through quick connector; 510. a first float switch receptacle; 511. a second float switch receptacle; 60. an electronic control module; 61. a mounting frame; 62. a main control board; 63. a switching power supply; 64. a power switch; 65. a filter; 66. an isolation transformer; 67. a servo motor driver; 70. a kit; 80. a sample tube; 90. a substrate tube.
Detailed Description
It should be noted that the embodiments and features of the embodiments in the present application may be combined with each other without conflict. The present application will be described in detail below with reference to the embodiments with reference to the attached drawings.
It is noted that the terminology used herein is for the purpose of describing particular embodiments only and is not intended to be limiting of example embodiments according to the present application. As used herein, the singular forms "a", "an", and "the" are intended to include the plural forms as well, and it should be understood that when the terms "comprises" and/or "comprising" are used in this specification, they specify the presence of stated features, steps, operations, devices, components, and/or combinations thereof, unless the context clearly indicates otherwise.
The relative arrangement of the components and steps, the numerical expressions, and numerical values set forth in these embodiments do not limit the scope of the present application unless specifically stated otherwise. Meanwhile, it should be understood that the sizes of the respective portions shown in the drawings are not drawn in an actual proportional relationship for the convenience of description. Techniques, methods, and apparatus known to those of ordinary skill in the relevant art may not be discussed in detail, but are intended to be part of the specification where appropriate. In all examples shown and discussed herein, any particular value should be construed as merely illustrative, and not limiting. Thus, other examples of the exemplary embodiments may have different values. It should be noted that: like reference numbers and letters refer to like items in the following figures, and thus, once an item is defined in one figure, further discussion thereof is not required in subsequent figures.
Referring to fig. 1 and 2, according to an embodiment of the present disclosure, there is provided a luminescence immunoassay analyzer including a rack 10, a reagent sample module 20, a detection module 30, a sample adding module 40, a liquid path module 50, and an electric control module 60.
Referring to fig. 3 to 8, the rack 10 includes a bottom plate 11 and a rack body 12 supported on the bottom plate 11; the reagent sample block 20 is provided on the bottom plate 11, the reagent sample block 20 includes a rotatably provided reagent loading tray 21, and the reagent loading tray 21 is provided with a reagent cartridge positioning portion 211, a sample tube positioning portion 212, and a substrate tube positioning portion 213; the detection module 30 is arranged on the bottom plate 11 and arranged side by side with the reagent sample module 20, the detection module 30 comprises a tray frame 31, a tray 32, a PMT (photomultiplier tube) assembly 33 and a needle washing pool 34, the tray 32 is rotatably arranged on the tray frame 31, the PMT assembly 33 is arranged at the bottom of the tray frame 31, and the needle washing pool 34 is arranged at the side edge of the tray frame 31; the sample adding module 40 comprises a guide rail assembly 41 and a sample adding needle assembly 42, the guide rail assembly 41 is arranged on the frame body 12, and the sample adding needle assembly 42 is slidably arranged on the guide rail assembly 41 to reciprocate between the reagent sample module 20 and the detection module 30 for sample adding; the liquid path module 50 is disposed on the bottom plate 11 and behind the reagent sample module 20 for delivering the cleaning liquid at least to the needle washing pool 34 and the needle feeding assembly 42; the electronic control module 60 is disposed on the bottom plate 11 and behind the detection module 30 to at least control the reagent sample module 20, the detection module 30, the sample adding module 40, and the liquid path module 50.
In this embodiment, the rear direction refers to a direction away from the operator when the luminescence immunoassay analyzer is used, and specifically, the rear direction is the front and rear direction shown in fig. 1.
In actual use, the reagent cartridge 70 is placed at the reagent cartridge positioning portion 211, the sample tube 80 containing the sample is placed at the sample tube positioning portion 212, the substrate tube 90 is placed at the substrate tube positioning portion 213, and the microfluidic disk is placed on the tray 32. The sample, reagents, substrates, etc. are then loaded into the microfluidic chip by the loading needle assembly 42 of the loading module 40, and thereafter, the rotational speed, direction, etc. of the tray 32 are controlled, and the sample is subjected to luminescence immunoassay by the PMT assembly 33. In the process of loading the sample by the sample loading needle assembly 42, the needle washing pool 34 can be extended into for washing according to the use requirement.
According to the structure of the luminous immunoassay analyzer of the application, the luminous immunoassay analyzer adopts the modular design, the whole structure comprises a rack 10 and a reagent sample module 20 arranged on the rack 10, a detection module 30, a sample adding module 40, a liquid path module 50 and an electric control module 60, the modular design mode can improve the compactness of the whole luminous immunoassay analyzer, and further the whole volume of the whole luminous immunoassay analyzer can be reduced, and the luminous immunoassay analyzer is more convenient to use and carry. Meanwhile, the modular design mode is adopted, and the luminous immunoassay analyzer is convenient to assemble and overhaul.
The respective modules of the luminescence immunoassay analyzer will be described in detail below.
As shown in fig. 1 to fig. 3, the rack 10 in this embodiment is substantially a structure similar to a rectangular parallelepiped, the bottom of the bottom plate 11 is provided with a shock absorbing foot 111, and the bottom plate 11 is provided with an air inlet mesh plate 112, so that air can enter the inside of the rack 10 from the air inlet mesh plate 112 to dissipate heat of a heating element and the like in the rack 10.
Further, be provided with structures such as upper cover 13, printer 14, display screen 15 and status indicator 16 on the frame 10 in this application, wherein, upper cover 13 sets up in the top of frame 10 with overturning, when opening upper cover 13, is convenient for control the luminous immunoassay appearance in order to carry out luminous immunodetection to samples such as blood. The printer 14 is used to print a corresponding detection report. The display screen 15 can be used for displaying information such as detection data and detection items of the luminescence immunoassay, and is also convenient for controlling the luminescence immunoassay analyzer. Alternatively, the display screen 15 may be a display screen such as a touch screen. Status indicator light 16 may be used to indicate the operating status of the luminescent immunoassay analyzer.
Referring to fig. 2, 4-5, the reagent sample module 20 of the present application further includes a heat sink 22, the heat sink 22 is disposed on the bottom plate 11, and the reagent loading tray 21 is rotatably disposed on the heat sink 22. Optionally, the heat dissipation assembly 22 includes a heat dissipation air duct metal plate 221 and a heat dissipation sheet 222 disposed inside the heat dissipation air duct metal plate 221, a fan 223 is disposed in the heat dissipation air duct metal plate 221, and when the fan 223 works, air can enter the heat dissipation air duct metal plate 221 from the air inlet mesh plate 112, so that a reagent, a sample, a substrate and the like placed on the reagent loading tray 21 can be cooled, and the reagent, the sample, the substrate and the like are prevented from deteriorating.
Further, the reagent loading disk 21 has an inner ring disk 2101 and an outer ring disk 2102 in which the outer periphery of the inner ring disk 2101 is provided, a plurality of reagent cartridge positioning portions 211 are provided at intervals in the circumferential direction of the inner ring disk 2101, and a plurality of sample tube positioning portions 212 and a plurality of substrate tube positioning portions 213 are provided at intervals in the outer periphery of the outer ring disk 2102. The plurality of reagent cartridge positioning portions 211, sample tube positioning portions 212, and substrate tube positioning portions 213 facilitate positioning of the plurality of reagent cartridges 70, sample tubes 80, and substrate tubes 90, and can improve the detection efficiency of the luminescence immunoassay analyzer of the present application. Alternatively, the cartridge positioning portion 211, the sample tube positioning portion 212, and the substrate tube positioning portion 213 in the present application may be a positioning groove, a positioning snap, or the like.
Further, the reagent sample module 20 further comprises a code scanning assembly 23 and a first motor 24, the code scanning assembly 23 is disposed on the heat dissipation assembly 22 and located outside the reagent loading tray 21, the first motor 24 is in driving connection with the reagent loading tray 21 to drive the reagent loading tray 21 to rotate, when the reagent loading tray 21 rotates, not only can the reagents in the reagent kit 70 be uniformly mixed, but also the sample tube 80 can be rotated to be opposite to the code scanning assembly 23, so that the code scanning assembly 23 can scan the sample tube 80. When the luminescence immunoassay analyzer works, after the code scanning assembly 23 scans the sample tube 80, the electronic control module 60 can be used to start the corresponding control program to perform detection analysis on the sample.
As shown in fig. 2, 6 to 10, the detecting module 30 in this embodiment further includes a cover plate 35, the cover plate 35 is disposed on the tray rack 31 in a turnable manner for covering or uncovering the tray 32, and the cover plate 35 is provided with a sample adding hole 351. In practical use, after the microfluidic disk is placed on the tray 32 and the cover plate 35 is covered, the microfluidic disk can be located in a relatively closed space, and then, through the effect of the sample adding hole 351, the reagents, the sample plates, the substrates and the like can be conveniently added into the microfluidic disk.
Optionally, the cover plate 35 in this embodiment is further provided with a magnetic switch 352, so that the cover plate 35 can be stably placed on the tray 32.
Further, the detection module 30 in this embodiment further includes a light-tight assembly for sealing at least the loading hole 351 and the PMT assembly 33. Specifically, the light-sealing unit in this embodiment includes a tubular electromagnet 361, and a first light-sealing member 362 is provided at an end of the tubular electromagnet 361, so that the tubular electromagnet 361 operates to seal the sample addition hole 351 with the first light-sealing member 362 after the addition of the reagent, the sample, the substrate, and the like is completed. Alternatively, the first sealing member 362 may be an elastic sealing block or the like. The light-tight assembly further comprises a lifting magnet 363 and a second light-tight piece 364 arranged at the end of the lifting magnet 363, when the lifting magnet 363 is lifted, light emitted by the photomultiplier tube on the PMT assembly 33 can be irradiated into the micro-fluidic disc on the tray 32 from the second light-tight piece 364, and is not interfered by the outside, so that the detection accuracy of the luminescence immunoassay analyzer in the embodiment can be further improved. Illustratively, the second light-tight member 364 in this embodiment is a light-shielding ring with elasticity.
Referring to fig. 7 to 10, a light shielding plate 311 is disposed on the periphery of the tray frame 31, and a second motor 37 is disposed at the bottom of the tray frame 31, wherein the second motor 37 is drivingly connected to the tray 32 to drive the tray 32 to rotate. The needle washing pool 34 is located between the tray frame 31 and the reagent sample module 20, and a liquid level sensor 341 is arranged at the bottom of the needle washing pool 34, so that the liquid level in the needle washing pool 34 can be conveniently detected, and the cleaning liquid in the needle washing pool 34 can be conveniently pumped out at a proper time. Alternatively, the reservoir 34 in this embodiment is a fountain-type reservoir, i.e., a manner in which cleaning solution is poured upwardly from the bottom of the reservoir 34 to clean the loading needle assembly 42.
Referring to fig. 2, 11-12, the fluid path module 50 of the present application includes a mounting plate 51, a cleaning fluid container (not shown), a waste fluid container (not shown), a plunger pump 54, a peristaltic pump 55, a waste fluid diaphragm pump 56, and a needle washing diaphragm pump 57. The mounting plate 51 is mounted on the base plate 11; the cleaning liquid container is connected with a first plate-penetrating quick-connection plug 58 arranged on the mounting plate 51; the waste liquid container is connected with a second plate-penetrating quick-plug connector 59 arranged on the mounting plate 51; the plunger pump 54 is in communication with the first through-plate quick-connect connector 58 for pumping the wash solution to the needle assembly 42; the peristaltic pump 55 is in communication with the first threading quick connector 58 for pumping the cleaning liquid to the needle wash basin 34; the waste liquid diaphragm pump 56 is in communication with the second plate-through quick-connect connector 59 for pumping condensate at the reagent sample module 20 to a waste liquid container; the needle washing diaphragm pump 57 is in communication with the second quick-connect plate 59 for pumping the waste liquid in the needle washing basin 34 to a waste liquid container. Further, the liquid path module 50 is further provided with a first float switch socket 510 and a second float switch socket 511, wherein the first float switch socket 510 is connected with a first float (not shown in the figure) for detecting the liquid level of the cleaning liquid container, and the second float switch socket 511 is connected with a second float (not shown in the figure) for detecting the liquid level of the waste liquid container.
Specifically, the liquid path module 50 in this embodiment is further provided with a three-way joint 52 and an electromagnetic valve 53, during actual connection, one end of the plunger pump 54 is communicated with the first plate-penetrating quick-plug connector 58, the other end of the plunger pump 54 is communicated with the first end of the three-way joint 52, one end of the peristaltic pump 55 is communicated with the second end of the three-way joint 52, the other end of the peristaltic pump 55 is communicated with the needle washing pool 34, the electromagnetic valve 53 is disposed on a pipe between the peristaltic pump 55 and the second end of the three-way joint 52, so as to control on/off of the pipe, and the third end of the three-way joint 52 is communicated with the sample injection needle assembly 42, so as to deliver the cleaning liquid to the sample injection needle assembly 42 to be used as the diluent.
Referring to fig. 2, 13 and 14, the sample application module 40 in this embodiment further includes a third motor 43 and a fourth motor 44, the third motor 43 is drivingly connected to the sample application needle assembly 42 to drive the sample application needle assembly 42 to reciprocate horizontally, the fourth motor 44 is drivingly connected to the sample application needle assembly 42 to drive the sample application needle assembly 42 to reciprocate vertically, and further, the sample application needle assembly 42 can be driven to reciprocate between the reagent sample module 20 and the detection module 30.
Specifically, the guide rail assembly 41 includes a horizontal guide rail 411 and a vertical guide rail 412, wherein the horizontal guide rail 411 is horizontally disposed on the frame body 12, the vertical guide rail 412 is movably disposed on the horizontal guide rail 411 and extends along a direction perpendicular to the horizontal guide rail 411, the loading needle assembly 42 is disposed on the vertical guide rail 412, when the third motor 43 rotates, the vertical guide rail 412 can be driven to move along the horizontal guide rail 411, and when the fourth motor 44 rotates, the loading needle assembly 42 can be driven to move along the vertical guide rail 412, which is simple in structure and convenient to implement. For example, the third motor 43 and the fourth motor 44 of the present application are both stepping motors, and have high control accuracy and good stability.
Further, the sampling needle assembly 42 includes a fixing block 421 and a sampling needle 422, wherein the fixing block 421 is slidably disposed on the vertical guide rail 412, the sampling needle 422 is fixedly mounted on the fixing block 421, and the third motor 43 and the fourth motor 44 can drive the fixing block 421 to move relative to the horizontal guide rail 411 and the vertical guide rail 412 when operating, so as to drive the sampling needle 422 to reciprocate between the reagent sample module 20 and the detection module 30 for reagent sampling and cleaning of the sampling needle 422, and the sampling needle assembly is simple in structure and convenient to control.
Referring to fig. 15, the electronic control module 60 in this embodiment is provided with a mounting bracket 61, a main control board 62, a switching power supply 63, a power switch 64, a filter 65, an isolation transformer 66, a servo motor driver 67, and the like. The mounting bracket 61 is installed on the base plate 11, and the main control board 62, the switching power supply 63, the power switch 64, the filter 65, the isolation transformer 66 and the servo motor driver 67 are all installed on the mounting bracket 61. The main control board 62 is connected to the reagent sample module 20, the detection module 30, the sample adding module 40, and the liquid path module 50 in a control manner, so as to control the reagent sample module 20, the detection module 30, the sample adding module 40, and the liquid path module 50. The switch power supply 63, the power switch 64, the filter 65, the isolation transformer 66, the servo motor driver 67 and other structures can regulate and control the voltage, the power on-off, the control signal and the like of the luminescence immunoassay analyzer.
For ease of description, spatially relative terms such as "over 8230 \ 8230;,"' over 8230;, \8230; upper surface "," above ", etc. may be used herein to describe the spatial relationship of one device or feature to another device or feature as shown in the figures. It will be understood that the spatially relative terms are intended to encompass different orientations of the device in use or operation in addition to the orientation depicted in the figures. For example, if a device in the figures is turned over, devices described as "above" or "on" other devices or configurations would then be oriented "below" or "under" the other devices or configurations. Thus, the exemplary terms "at 8230; \8230; above" may include both orientations "at 8230; \8230; above" and "at 8230; \8230; below". The device may be otherwise variously oriented (rotated 90 degrees or at other orientations) and the spatially relative descriptors used herein interpreted accordingly.
It should be noted that the terms "first", "second", and the like are used to define the components, and are only used for convenience of distinguishing the corresponding components, and the terms have no special meanings unless otherwise stated, and therefore, the scope of protection of the present application is not to be construed as being limited.
The above description is only a preferred embodiment of the present application and is not intended to limit the present application, and various modifications and changes may be made by those skilled in the art. Any modification, equivalent replacement, improvement and the like made within the spirit and principle of the present application shall be included in the protection scope of the present application.

Claims (10)

1. A luminescence immunoassay analyzer, comprising:
the rack (10) comprises a bottom plate (11) and a rack body (12) supported and arranged on the bottom plate (11);
a reagent sample module (20), wherein the reagent sample module (20) is arranged on the bottom plate (11), the reagent sample module (20) comprises a rotatably arranged reagent loading tray (21), and a reagent kit positioning part (211), a sample tube positioning part (212) and a substrate tube positioning part (213) are arranged on the reagent loading tray (21);
a detection module (30), wherein the detection module (30) is arranged on the bottom plate (11) and is arranged side by side with the reagent sample module (20), the detection module (30) comprises a tray frame (31), a tray (32), a PMT assembly (33) and a needle washing pool (34), the tray (32) is rotatably arranged on the tray frame (31), the PMT assembly (33) is arranged at the bottom of the tray frame (31), and the needle washing pool (34) is arranged at the side edge of the tray frame (31);
a sample application module (40), wherein the sample application module (40) comprises a guide rail assembly (41) and a sample application needle assembly (42), the guide rail assembly (41) is arranged on the frame body (12), and the sample application needle assembly (42) is slidably arranged on the guide rail assembly (41) to reciprocate between the reagent sample module (20) and the detection module (30);
a liquid path module (50), wherein the liquid path module (50) is arranged on the bottom plate (11) and is positioned behind the reagent sample module (20) so as to at least convey a cleaning liquid to the needle washing pool (34) and the sample adding needle assembly (42); and
an electronic control module (60), wherein the electronic control module (60) is disposed on the bottom plate (11) and behind the detection module (30) to at least control the reagent sample module (20), the detection module (30), the sample adding module (40) and the liquid path module (50).
2. The luminescent immunoassay analyzer of claim 1, wherein the reagent sample module (20) further comprises:
the heat dissipation assembly (22), the heat dissipation assembly (22) is arranged on the bottom plate (11), and the reagent loading plate (21) is rotatably arranged on the heat dissipation assembly (22).
3. The luminescent immunoassay analyzer of claim 1, wherein the reagent loading tray (21) has an inner ring tray (2101) and an outer ring tray (2102) provided at the outer periphery of the inner ring tray (2101), a plurality of the reagent cartridge positioning parts (211) are provided at intervals in the circumferential direction of the inner ring tray (2101), and a plurality of the sample tube positioning parts (212) and a plurality of the substrate tube positioning parts (213) are provided at intervals at the outer periphery of the outer ring tray (2102).
4. The luminescence immunoassay analyzer of claim 2, wherein the reagent sample module (20) further comprises a code scanning assembly (23) and a first motor (24), the code scanning assembly (23) is disposed on the heat dissipation assembly (22) and located outside the reagent loading tray (21), and the first motor (24) is drivingly connected to the reagent loading tray (21) for driving the reagent loading tray (21) to rotate.
5. The luminoimmunoassay analyzer according to claim 1, wherein the detection module (30) further comprises a cover plate (35), the cover plate (35) is reversibly arranged on the tray rack (31) for covering or uncovering the tray (32), and the cover plate (35) is provided with a sample adding hole (351).
6. The luminoimmunoassay analyzer of claim 5, wherein the detection module (30) further comprises a light-tight assembly for sealing at least the loading well (351) and the PMT assembly (33).
7. The luminescence immunoassay instrument according to claim 1, wherein a light shielding plate (311) is arranged on the periphery of the tray frame (31), a second motor (37) is arranged at the bottom of the tray frame (31), and the second motor (37) is in driving connection with the tray (32) to drive the tray (32) to rotate.
8. The luminescent immunoassay analyzer of claim 1, wherein the needle wash basin (34) is located between the tray rack (31) and the reagent sample module (20), and a liquid level sensor (341) is provided at a bottom of the needle wash basin (34).
9. The luminescent immunoassay analyzer of claim 1, wherein the liquid path module (50) comprises:
a mounting plate (51), the mounting plate (51) being mounted to the base plate (11);
the cleaning liquid container is connected with a first plate-penetrating quick-plugging connector (58) arranged on the mounting plate (51);
the waste liquid container is connected with a second plate penetrating quick-connection plug (59) arranged on the mounting plate (51);
a plunger pump (54), the plunger pump (54) in communication with the first through-plate quick-connect connector (58) for pumping a wash solution to the needle assembly (42);
a peristaltic pump (55), the peristaltic pump (55) being in communication with the first threading quick connector (58) for pumping a cleaning liquid to the needle wash basin (34);
a waste liquid diaphragm pump (56), the waste liquid diaphragm pump (56) being in communication with the second through-plate quick-connect connector (59) for pumping condensate at the reagent sample module (20) to the waste liquid container;
and the needle washing diaphragm pump (57), the needle washing diaphragm pump (57) is communicated with the second plate penetrating quick-plug connector (59) to pump the waste liquid in the needle washing pool (34) to the waste liquid container.
10. The luminescence immunoassay analyzer of any one of claims 1 to 9, wherein the sample application module (40) further comprises a third motor (43) and a fourth motor (44), the third motor (43) is drivingly connected to the sample application needle assembly (42) to drive the sample application needle assembly (42) to reciprocate horizontally, and the fourth motor (44) is drivingly connected to the sample application needle assembly (42) to drive the sample application needle assembly (42) to reciprocate vertically.
CN202221279519.4U 2022-05-23 2022-05-23 Luminous immunity analyzer Active CN217786910U (en)

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Application Number Priority Date Filing Date Title
CN202221279519.4U CN217786910U (en) 2022-05-23 2022-05-23 Luminous immunity analyzer

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202221279519.4U CN217786910U (en) 2022-05-23 2022-05-23 Luminous immunity analyzer

Publications (1)

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CN217786910U true CN217786910U (en) 2022-11-11

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