CN217156538U

CN217156538U - Incubation unit and sample analyzer

Info

Publication number: CN217156538U
Application number: CN202123434176.2U
Authority: CN
Inventors: 方泉; 练子富; 李临
Original assignee: Kemei Boyang Diagnostic Technology Shanghai Co ltd
Current assignee: Kemei Boyang Diagnostic Technology Shanghai Co ltd
Priority date: 2021-12-31
Filing date: 2021-12-31
Publication date: 2022-08-09
Anticipated expiration: 2031-12-31

Abstract

The present application relates to an incubation unit and a sample analyzer. The incubation unit comprises a body and a separate injection disc, wherein the separate injection disc is used for placing the reaction containers and can drive the reaction containers to move to different stations; the positioning assembly comprises a first driving part and a clamping part connected with the first driving part, the first driving part can drive the clamping part to move, and the clamping part can be clamped with the reaction container to position the reaction container; the abandon cup assembly comprises a second driving part and a pushing part, the second driving part is used for driving the pushing part to move, and the pushing part is used for separating the reaction vessel from the dispensing disc and pushing the reaction vessel to a preset position; the position detection assembly comprises at least one detection part, and the detection part is at least used for detecting the position reached by the reaction container pushed by the pushing part. The scheme that this application provided, through sequential control with multistation integration in an organic whole, the whole high-efficient accuracy of operation, the reliability is high.

Description

Incubation unit and sample analyzer

Technical Field

The application relates to the technical field of medical equipment, in particular to an incubation unit and a sample analyzer.

Background

A sample analyzer (biochemical analysis, immunoassay analyzer) is an instrument for detecting a specific substance in blood. In order to obtain a detection signal, the liquid in the cuvette is usually subjected to a specific reaction, such as a biochemical reaction, an immunological reaction. This reaction generally needs to be carried out under defined temperature conditions. If the reaction temperature does not meet the prescribed temperature, the reaction does not proceed sufficiently and a correct detection signal cannot be obtained. The incubation unit is an important component of the sample analyzer, is used for providing proper temperature for the reaction container, and needs to meet the procedures of sample introduction, liquid adding, detection, unloading and the like, and for the incubation unit, the conversion, the performance and the like among the procedures have great influence on the accuracy and the precision of the detection result.

SUMMERY OF THE UTILITY MODEL

In order to solve or partially solve the problem that exists among the correlation technique, this application provides an incubate unit and sample analysis appearance, through time sequence control with the multistation integration in an organic whole, the whole high efficiency accuracy of operation, the reliability is high.

A first aspect of the application provides an incubation unit for a sample analyzer, the incubation unit comprising:

the body at least comprises a cup feeding station, a sample adding and mixing station, a detection station and a cup abandoning station;

the dispensing disc is movably connected to the body and used for placing the reaction containers, and the action of the dispensing disc can drive the reaction containers to move to different stations;

the detection station is provided with a positioning assembly, the positioning assembly comprises a first driving part and a clamping part connected with the first driving part, the first driving part can drive the clamping part to move, and the clamping part can be clamped with the reaction container to position the reaction container;

the cup abandoning station is provided with a cup abandoning component and a position detection component,

the cup abandoning assembly comprises a second driving part and a pushing part which are matched, the second driving part is used for driving the pushing part to move, when the reaction container moves to the cup abandoning station, the pushing part is used for separating the reaction container from the dispensing disc and pushing the reaction container to a preset position,

the position detection assembly comprises at least one detection part, and the detection part is at least used for detecting the position reached by the reaction container pushed by the pushing part.

A second aspect of the present application provides a sample analyzer comprising an incubation unit as described in the above.

The technical scheme provided by the application can comprise the following beneficial effects: the positioning assembly arranged in the incubation unit can assist in positioning the dispensing disc through the positioning assembly, so that the target reaction container can stop at the corresponding station when rotating along with the dispensing disc, and the position precision is higher. The cup discarding assembly is beneficial to discarding the target reaction vessel to a fixed position at a cup discarding station more stably and more accurately. The position detection assembly can monitor the position of the target reaction vessel in the discarding cup assembly, and the blockage in the discarding cup assembly is avoided. Through the design of integrating a plurality of stations that use in with sample analysis in an organic whole for it has higher integrated level to incubate the unit, can make things convenient for quick convert reaction vessel to different stations, and can maintain reaction vessel at suitable temperature throughout in the conversion process, with the stability and the degree of accuracy of guaranteeing to incubate the result.

It is to be understood that both the foregoing general description and the following detailed description are exemplary and explanatory only and are not restrictive of the application.

Drawings

The foregoing and other objects, features and advantages of the application will be apparent from the following more particular descriptions of exemplary embodiments of the application, as illustrated in the accompanying drawings wherein like reference numbers generally represent like parts throughout the exemplary embodiments of the application.

FIG. 1 is a schematic diagram of the overall structure of an incubation unit shown in the embodiment of the present application;

FIG. 2 is a schematic partial perspective structural view of an incubation unit according to an embodiment of the present application;

FIG. 3 is a schematic view of a portion of the structure of FIG. 2;

fig. 4 is a schematic structural diagram of the whole positioning assembly in the incubation unit shown in the embodiment of the present application;

FIG. 5 is a front view of a positioning assembly in an incubation unit shown in an embodiment of the present application;

FIG. 6 is a schematic diagram of the overall structure of a disposable cup assembly in an incubation unit according to an embodiment of the present application;

FIG. 7 is a schematic diagram of a cross-sectional structure of a disposable cup assembly in an incubation unit according to an embodiment of the present application;

FIG. 8 is a schematic cross-sectional view of another disposable cup assembly in an incubation unit according to an embodiment of the present application.

Detailed Description

Embodiments of the present application will be described in more detail below with reference to the accompanying drawings. While embodiments of the present application are illustrated in the accompanying drawings, it should be understood that the present application may be embodied in various forms and should not be limited to the embodiments set forth herein. Rather, these embodiments are provided so that this disclosure will be thorough and complete, and will fully convey the scope of the disclosure to those skilled in the art.

The terminology used herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the application. As used in this application and the appended claims, the singular forms "a", "an", and "the" are intended to include the plural forms as well, unless the context clearly indicates otherwise. It should also be understood that the term "and/or" as used herein refers to and encompasses any and all possible combinations of one or more of the associated listed items.

It should be understood that although the terms "first," "second," "third," etc. may be used herein to describe various information, these information should not be limited to these terms. These terms are only used to distinguish one type of information from another. For example, first information may also be referred to as second information, and similarly, second information may also be referred to as first information, without departing from the scope of the present application. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more of that feature. In the description of the present application, "a plurality" means two or more unless specifically limited otherwise.

A sample analyzer (e.g., biochemical analysis, immunoassay analyzer) is an instrument for detecting a specific substance in blood. The incubation unit is an important component of the sample analyzer for providing the reaction vessel with a suitable temperature to meet the incubation requirements. In addition, in the incubation process, the operations of sample introduction, sample adding mixing, detection, unloading and the like are required to be carried out on the sample, and in the series of operation processes, the reaction container is always ensured to be at a proper temperature, so that the incubation result is prevented from being influenced. When the reaction container is switched to different positions in the incubation unit for corresponding operation, the switching process is not tightly connected, the stability is poor, the reaction container is not easy to be always maintained at a proper temperature, and the final sample analysis result is easily influenced under the influence of the factors in various aspects.

To above-mentioned problem, this application embodiment provides an incubation unit, and the design that the multistation integrates has guaranteed the accuracy of operation high efficiency, stability and testing result.

The technical solutions of the embodiments of the present application are described in detail below with reference to the accompanying drawings.

Fig. 1 is a schematic view of the overall structure of an incubation unit shown in the embodiment of the present application.

Fig. 2 is a schematic structural diagram of a partial perspective view of an incubation unit shown in an embodiment of the present application.

Fig. 3 is a partial structural view of fig. 2.

Referring to fig. 1 to 3, the incubation unit includes a body 1, the body 1 at least includes a cup feeding station 1a, a sample adding and mixing station 1b, a detection station 1c, and a cup discarding station 1d, a dispensing disc 6 is movably connected to the body 1 for placing a reaction container 5, and the action of the dispensing disc 6 can drive the reaction container 5 to move to different stations. The incubation unit further comprises a positioning assembly 4 located at the detection station 1c, a cup discarding assembly 2 located at the cup discarding station 1d, and a position detection assembly 3. A plurality of stations with different operations in the incubation process are integrated in the body, and the reaction container 5 can be conveniently and stably switched to the corresponding station by driving the separate injection disc 6 to act, so that the integration level is high, and the ordered and stable proceeding of each step is ensured.

In an embodiment, the body 1 includes a housing 11, an incubation disc 13, and a top cover 12, the top of the housing 11 has an open end, the top cover 12 covers the open end and is detachably connected to the housing 11 to form an accommodation cavity 111, the incubation disc 13 is disposed on an inner wall of the housing 11, and the dispensing disc 6 and the incubation disc 13 are located in the accommodation cavity 111. On the one hand, this arrangement allows the reaction vessels 5 located on the dispensing disk 6 to be always located in the accommodating cavities 111 during the movement, so that the reaction vessels 5 can be always maintained at the set temperature. On the other hand, the arrangement mode of limiting the reaction vessel 5 in the accommodating cavity 111 avoids the situation that the reaction vessel 5 is influenced by external factors to generate the jumping in the axial direction. In yet another aspect, the reaction vessels 5 on the dispensing disc 6 are protected from light.

Wherein, the position that top cap 12 corresponds application of sample mixing station 1b is equipped with at least one through-hole 121, can add liquid from through-hole 121 externally when reaction vessel 5 is located application of sample mixing station 1b, and liquid includes but not limited to sample, reagent and general liquid to obtain mixed liquid after making reaction vessel 5 in the liquid application mixing.

Optionally, the incubation unit includes a heating component, and the heating component is disposed in the accommodating cavity 111 and is configured to heat the accommodating cavity 111, so that the accommodating cavity 111 is maintained at a desired suitable temperature. It is understood that the heating assembly may be a heating pipeline uniformly arranged on the inner wall of the incubation plate 13 or the housing 11, or other heating device capable of heating the accommodating cavity 111 to maintain the reaction container 5 therein at a suitable temperature, and is not limited in particular.

And in order to guarantee that the reaction vessel 5 that is located holding chamber 111 can both have more stable temperature when moving to different stations, guarantee that the temperature is in required scope, at least one side of top cap 12 can be covered with the heat preservation, and through-hole 121 runs through the heat preservation. The temperature diffusion in the accommodating cavity 111 can be avoided too fast through the arrangement of the heat preservation layer, so that the heat preservation effect is achieved. Optionally, other side walls of the housing 11 for forming the accommodating cavity 111 may also be covered with an insulating layer, so as to improve the insulating performance of the accommodating cavity 111. For the heat preservation layer, the light-tight material with heat preservation performance can be selected for use to play light-tight effect when playing better heat preservation effect, avoid influencing the sample analysis result.

Optionally, the body 1 may further include a shielding assembly, the shielding assembly is located on the top cover 12, and the shielding assembly includes: at least one apron and power portion, power portion can drive the apron and rotate to it can cover or open through-hole 121 to drive the apron. Through the apron that sets up, can detect when reaction vessel 5 is in application of sample mixing station 1b, control power portion rotates the apron in order to open through hole 121 to can make things convenient for quick liquid feeding mixing operation of carrying on. After the temperature control is completed, the power part control cover plate covers the through hole 121, so that the path of temperature diffusion in the accommodating cavity 111 is reduced, and the heat preservation effect in the accommodating cavity 111 is improved. Other matching structures for the shielding assembly for opening or closing one or more through holes 121 can be provided, and are not described in detail herein.

In an embodiment, the cup feeding station 1a, the sample adding and mixing station 1b, the detection station 1c and the cup discarding station 1d are circumferentially arranged on the body 1 according to a time sequence, the dispensing disc 6 is rotatably connected to the accommodating cavity 111, so that the dispensing disc 6 can rotate around the axis of the body 1 to drive the reaction containers 5 to circumferentially rotate to the corresponding stations according to the preset time sequence and start and stop after reaching the positions, the dispensing disc 6 is circumferentially provided with a plurality of accommodating positions 61, and the accommodating positions 61 are used for accommodating the reaction containers 5. The rotation and the time sequence of the dispensing disc 6 are combined by the circumferential arrangement of the stations, so that the reaction containers 5 arranged on the dispensing disc 6 can complete the complete sample analysis before completing one rotation, and the reaction containers 5 can be filled into the dispensing disc 6 and discarded. And along with the process of presetting the time sequence and rotating along the circumferential direction, according to the sequence that reaction vessel 5 got into, can realize the continuous work of a plurality of reaction vessels 5, improved sample analysis efficiency. This kind of mode is integrated in an organic whole with each process, and a plurality of positions 61 of holding are circumference evenly arranged, as long as hold position 61 pivoted angle and interval how long as rotate relevant parameter and chronogenesis's injecture can make things convenient for fast rotate reaction vessel 5 to corresponding station, and the whole operation is high-efficient accurate, and the reliability is higher.

It can be understood that the incubation unit further comprises a support 11b, the body 1 is located on the support 11b, a support shaft rotatably connected to the support 11b at least partially penetrates the housing 11 and the incubation disk 13 to be connected to the dispensing disk 6, and a third driving unit 11a is connected to the support shaft for rotating the support shaft to rotate the dispensing disk 6 around the axis of the body 1. In order to rotate the dispensing disk 6, the support shaft may be fixedly connected to the dispensing disk 6 by a link, the axis of the support shaft coincides with the axis of the main body 1, and the third driving unit 11a drives the support shaft to rotate, so as to rotate the dispensing disk 6.

Alternatively, the third driving portion 11a may be a driving motor disposed on the supporting seat 11b, and the driving motor drives the supporting shaft to rotate so that the connecting rod drives the dispensing disc 6 to rotate around the axis of the body 1. Or the structure that the motor is matched with the synchronous belt wheel can be adopted, the output shaft of the motor is connected with the first belt wheel, the second belt wheel is positioned on the supporting seat 11b, the first belt wheel and the second belt wheel are connected through the first synchronous belt, and the supporting shaft of the second belt wheel, which is coaxially connected, at least partially penetrates through the shell 11, so that the supporting shaft positioned in the accommodating cavity 111 is fixedly connected with the dispensing disc 6 through the connecting rod, and the axis of the supporting shaft is superposed with the axis of the body 1. With the rotation that can more accurate control branch injection dish 6 through the cooperation of first hold-in range, promote the precision that reaction vessel 5 moved to different stations.

In an embodiment, the cup inlet 112 is correspondingly formed on the housing 11, the top cover 12 and the incubation disc 13 corresponding to the position of the cup inlet station 1a of the body 1, so that an operator can conveniently and quickly place the reaction container 5 in the accommodating position 61 corresponding to the position of the cup inlet 112. The reaction vessel 5 includes a vessel body 51 and a vessel shoulder 52 projecting radially outward, and when the reaction vessel 5 is placed at the receiving position 61, the vessel shoulder 52 is located above the receiving position 61, and the bottom surface of the vessel shoulder 52 is in contact engagement with the surface of the dispensing disk 6, thereby supporting the reaction vessel 5 on the dispensing disk 6.

In order to facilitate placing the reaction vessels 5 in the receiving locations 61 or removing the reaction vessels 5 from the receiving locations 61, the receiving locations 61 may be recesses provided at the edge of the dispensing disk 6 and having openings 611 from which the reaction vessels 5 can be placed or removed in the radial direction. The accommodating position 61 is directly set in a groove structure formed on the edge opening 611 of the dispensing disc 6, so that the reaction container 5 can be directly extruded into the groove from the cup inlet 112 of the cup inlet station 1a in the rotating process of the dispensing disc 6, and the reaction container 5 is connected to the dispensing disc 6 through the matching of the container shoulder 52 and the dispensing disc 6, the structure is simple, and the cup inlet efficiency is improved.

Optionally, when the reaction container 5 enters the accommodating position 61, in order to complete the cup entering work at the cup entering station 1a and improve the sample injection efficiency, on the basis that the accommodating position 61 is set to the above structure, the size of the accommodating position 61 is set to be larger than that of the reaction container 5, that is, a fit gap is formed between the accommodating position and the reaction container, and the container shoulder 52 of the reaction container 5 is supported on the dispensing disc 6, so as to facilitate the cup entering.

In an embodiment, the detection station 1b is provided with a positioning assembly 4, the positioning assembly 4 includes a first driving portion 41 and a connected clamping portion 42, the first driving portion 41 can drive the clamping portion 42 to move, and the clamping portion 42 can be clamped with the reaction container 5 to position the reaction container 5. Through the positioning assembly 4, the reaction vessel 5 moving to the detection station 1c can be positioned in an auxiliary manner, the precision of the stop position of the reaction vessel 5 driven by the dispensing disc 6 in the moving process can be improved, and the situation that the reaction vessel 5 is easy to shift when stopping at the corresponding station is avoided.

Optionally, when there is a fit clearance between the reaction vessel 5 and the accommodating position 61, the reaction vessel 5 enters the accommodating position 61 corresponding to the cup inlet 112 through the cup feeding station 1 a. When the dispensing disc 6 drives the reaction vessel 5 to enter the detection station 1b, the dispensing disc 6 is controlled to stop rotating, so that the vessel mouth of the reaction vessel 5 can be opposite to the detection position of the detection station 1 c. However, since the reaction vessels 5 have a fit clearance with respect to the receiving locations 61, when the rotation of the dispensing disk 6 is controlled to stop, the positions of the reaction vessels 5 with respect to the receiving locations 61 may be different from the positions of the reaction vessels 5 during movement, which may cause a deviation in the reaction vessels 5 finally positioned at the detection positions, thereby causing a problem that the detection cannot be completed. Therefore, the positioning assembly 4 is arranged to perform auxiliary positioning, the dispensing disc 6 drives the reaction vessel 5 to rotate to the detection station 1c, and the clamping portion 42 moves to be clamped with the reaction vessel 5 to limit the relative movement between the reaction vessel 5 and the accommodating position 61. Thereby play limiting displacement to reaction vessel 5 through joint portion 42 for reaction vessel 5 can be more accurate fix a position the detection position, avoid taking place the skew.

Specifically, along with the rotation of the dispensing disk 6, the reaction container 5 subjected to sample adding and mixing can be driven to continue rotating from the sample adding and mixing station 1b to the direction of the detection station 1 c. When the reaction vessel 5 is detected to reach the detection station 1c, the first driving portion 41 is controlled to drive the clamping portion 42 to act, the clamping portion 42 moves towards the direction close to the detection station 1c along the radial direction of the body 1, and the clamping portion 42 is clamped with the reaction vessel 5 corresponding to the detection station 1 c. Through the joint of joint portion 42 and reaction vessel 5 for reaction vessel 5 can be accurate fix a position to the detection position in detecting station 1c, improves positioning accuracy. Moreover, when the dispensing disk 6 stops at the detection station 1c, if the dispensing disk 6 cannot stop in time due to inertia or the like, the relative position of the reaction vessel 5 at the receiving station 61 is different between the moving state and the stopping state of the dispensing disk 6, which affects the accuracy of the reaction vessel 5 at the detection position after the dispensing disk 6 stops, and the provision of the engaging portion 42 can compensate for such a deficiency, thereby ensuring the positioning accuracy of the reaction vessel 5 at the detection station 1 c.

Optionally, the incubation disk 13 is at least located on the bottom wall and the side wall in the housing 11, and the incubation disk 13 located on the side wall is in clearance fit with the edge of the dispensing disk 6, so as to limit the reaction vessels 5 in the accommodating positions 61 from being separated during rotation of the dispensing disk 6. The positioning assembly 4 is disposed on the bottom wall of the incubation disc 13 in the accommodating cavity 111, the first driving portion 41 is fixedly connected to the incubation disc 13, and the first driving portion 41 is controlled to drive the clamping portion 42 to move along the radial direction to clamp or release the clamping with the corresponding reaction vessel 5.

To detecting station 1c, the body 1 position that corresponds is equipped with detection assembly, and is equipped with at least one through-hole corresponding to detecting station 1 c's top cap 12 position, and when reaction vessel 5 ran to detecting station 1c, the through-hole can be relative with reaction vessel 5 for detection assembly passes through the through-hole and detects the mixed liquid in reaction vessel 5. And in order to make the holding chamber 111 have heat preservation, shading effect, the detecting component is including setting up in the shell 10 of top cap, and shell 10 shelters from the through-hole, and detecting component such as the detector for detect sets up in inside shell 10. The detector for detecting the mixed solution may be, for example, a light detection unit that detects the mixed solution in the reaction vessel 5 by passing laser light through the through hole, and the light detection unit is fixed to the top cover 12 or the housing 11.

It can be understood that the reaction vessel 5 is rotated by the dispensing disk 6 which rotates about the axis of the body 1, and when it is detected that the reaction vessel 5 has rotated to the detection station 1c, the dispensing disk 6 is controlled to stop rotating so as to position the reaction vessel 5 at the detection station 1 c. Due to the deviation of the precision problems such as control rotation and matching caused by long-term wear of the equipment, the reaction container 5 is easy to be positioned at the detection station 1c, so that the relative position of the through hole and the reaction container 5 gradually deviates, and the detection of the mixed liquid in the reaction container 5 is influenced. Therefore, the positioning assembly 4 is disposed at a position closer to the detection station 1c in the accommodating cavity 111, so that when it is detected that the reaction container 5 after sample injection and mixing rotates to the detection station 1c, a stop command is issued to the third driving part 11a for controlling the dispensing disc 6 to stop rotating, and the command is also sent to the first driving part 41 of the positioning assembly 4, and the first driving part 41 and the third driving part 11a simultaneously operate, so that the dispensing disc 6 stops moving, and the clamping part 42 is clamped with the reaction container 5, thereby realizing double positioning of the reaction container 5, and improving the precision and stability of positioning the reaction container 5 at the detection station 1 c.

As a specific embodiment of the present application, referring to fig. 4 and 5, for the provided clamping portion 42, the clamping portion 42 may include a fixture block 421 having a clamping groove 422, and the fixture block 421 is connected to the output end of the first driving portion 41, and can drive the fixture block 421 to move along the radial direction to the clamping groove 422 to abut against the reaction container 5. The first driving portion 41 can push the fixture block 421 to approach or separate from the sidewall of the incubation disc 13 along the radial direction of the body 1, and a clamping groove 422 is disposed on one side of the fixture block 421 facing the sidewall of the incubation disc 13, and the clamping groove 422 may be, for example, a V-shape or an arc shape recessed inwards along the radial direction of the body 1. The structure is simple in matching and easy to realize.

Optionally, the clamping groove 422 is configured as a symmetrical V-shaped structure, and the outer wall of the reaction container 5 facing to the clamping groove 422 is an arc-shaped surface. The V-shaped clamping groove 422 can be adapted to clamping matching with reaction containers 5 of different shapes, and the positioning assembly 4 does not need to be replaced. In addition, the V-shaped clamping groove 422 can better clamp the reaction vessel 5 through the two V-shaped side faces, so that the positioning precision is improved, and shaking is avoided.

Alternatively, the fastening portion 42 may also include a fastener and a hook, one of which is disposed at the output end of the first driving portion 41, and the other is disposed at the reaction container 5. The output end of the first driving portion 41 may be connected to a supporting block, the fastener is disposed on the supporting block, and the hook is disposed on the outer sidewall of the reaction vessel 5. First drive division 42 moves and drives the buckle and is close to hatching the dish 13 motion along body 1 radial direction, realizes the joint to buckle and pothook to realize fixing a position reaction vessel 5 in detection station 1c through joint between them. Alternatively, the matching structure of the arranged buckle and the hook can be realized by automatic control, the buckle is a ring-shaped or hook-shaped structure arranged on the reaction vessel 5, and when the buckle is detected to be abutted against the preset position of the hook, the hook can be controlled to rotate to be buckled with the buckle. After the detection is finished, the clamping hook is controlled to rotate reversely to be buckled with the buckle.

It should be emphasized that the engaging portion 42 may be provided with other engaging structures capable of engaging and disengaging, which are not listed here.

And to the first drive portion 41 that sets up, in order to improve the positioning accuracy and the positioning stability of joint portion 42, first drive portion 41 can include motor 411, motor 411 fixed connection is in the holding chamber 111 of body 1, the guide part includes complex screw rod 412 and slider 413, the extending direction of screw rod 412 is parallel with the radial direction of body 1, slider 413 swing joint is in screw rod 412, motor 411 can drive the screw rod 412 of connecting and rotate, so as to drive slider 413 along the extending direction motion of screw rod 412, thereby make joint portion 42 can realize the joint or release the joint to reaction vessel 5. Through setting up to the vice structure cooperation form of screw nut for the rotation of motor 411 drive screw 412 can drive the slider 413 with screw 412 screw-thread fit slides along body 1 radial direction, and this kind of structure cooperation can be more accurate control slider 413's direction of motion and movement distance, avoids joint portion 42 to reduce the stability and the precision of joint because of excessive movement or undermotion.

In an optional embodiment, the positioning assembly 4 may further include a stroke control portion 414 for controlling the reciprocating motion of the sliding block 413, the stroke control portion 414 may be a stroke switch disposed at the bottom of the incubation disc 13, when the clamping portion 42 is clamped with the reaction container, the stroke switch sends a signal to control the clamping portion 42 to stop moving, so as to prevent the clamping portion 412 from pressing the reaction container 5 to deform or damage the reaction container 5 due to the over-movement of the sliding block 413; meanwhile, the control clamping portion 42 is kept in a static state within a set time, so that the stability of the reaction container 5 is ensured when the detection device detects a sample to be detected within the set time. When the set time is reached, the motor 411 is controlled to rotate reversely to withdraw the slide block, so that the clamping part 413 and the reaction vessel 5 are released from clamping.

It is understood that the stroke control portion 414 may be other structures capable of achieving the purpose of forming control, such as an optocoupler, which is not listed here.

Optionally, no matter what structure cooperation form the positioning assembly 4 is set to, when the clamping portion 42 is matched with at least one reaction container 5 to position the reaction container 5 with the mixed liquid at the detection station 1c, in order to control the rotation of the dispensing disc 6 conveniently and enable the reaction container 5 to be accurately positioned at different stations, the plurality of containing positions 61 are uniformly arranged along the circumference of the dispensing disc 6, and a preset angle is formed between adjacent containing positions 61, and when the dispensing disc 6 rotates by one preset angle, the clamping portion 42 is controlled to be clamped with the reaction container 5. The preset angle set between adjacent receiving positions 61 may be adaptively adjusted according to specific conditions such as the rotation speed of the dispensing disk 6, the angle between different stations, or the reaction speed for controlling the operation of each driving unit, and is not particularly limited herein.

In one embodiment, referring to fig. 6 and 7, in the cup discarding station 1d of the body 1, the reaction vessel 5 containing the detected mixture is discharged from the dispensing tray 6 and discarded into the collecting device, and this is achieved by the cup discarding assembly 2 disposed in the cup discarding station 1 d. The discarding cup assembly 2 comprises a second driving part 22 and a pushing part 23 which are matched, the second driving part 22 is used for driving the pushing part 23 to move, and when the reaction vessel 5 moves to the discarding cup station 1d, the pushing part 23 is used for separating the reaction vessel 5 from the dispensing disc 6 and pushing the reaction vessel to a preset position. The disposal cup assembly 2 is provided to facilitate the disposal of the reaction vessel 5 to a fixed position at the disposal cup station 1d with more stability and higher accuracy.

The pushing part 23 is connected to the matching assembly 221, the matching assembly 221 is used for driving the pushing part 23 to move, the driving assembly 222 can provide power for the movement of the matching assembly 221, when the reaction container moves to the cup discarding station 1d, the driving assembly 222 can drive the matching assembly 221 to move, the matching assembly 221 drives the pushing part 23 to move, and the pushing part 23 is used for separating the reaction container 5 from the dispensing disc 6 and pushing the reaction container 5 to a preset position. The second driving portion 22 is formed by disposing the driving member 222 and the fitting member 221 separately. If the pushing portion 23 is directly driven by the driving mechanism, the driving mechanism under high-speed operation cannot be immediately stopped after receiving a start or stop command, which easily causes the situation that the pushing portion 23 is over-moved or stopped before reaching a set position. Therefore, by arranging the driving component 222 and the matching component 221 which are matched, the matching component 221 is used as a buffer, so that the positioning precision of the pushing part 23 can be controlled more accurately and stably, and the problem that the positioning precision of the driving mechanism is not high is solved. Moreover, the driving module 222 and the matching module 221 are arranged to improve the positioning accuracy of the pushing unit 23, and simultaneously, the reaction vessels 5 can be smoothly separated from the dispensing disc 6 and pushed in the first channel 213, so that the pushing unit 23 is prevented from pressing and blocking the reaction vessels 5 in the first channel 213 when the positioning accuracy is not high.

Abandon cup subassembly 2 and include mounting bracket 21, mounting bracket 21 is connected in the position that body 1 corresponds abandon cup station 1d, and mounting bracket 21 has the first passageway 213 with holding chamber 111 intercommunication, and second drive division 22 is connected in mounting bracket 21, and push portion 23 is connected with second drive division 22, and second drive division 22 is used for driving push portion 23 to move.

It is understood that the body 1 is provided with a cup outlet 113 penetrating the housing 11 and the incubation disk 13 corresponding to the cup discarding station 1d, the cup outlet 113 is communicated with the first channel 213, the first channel 213 extends in the radial direction of the body 1 and passes through the cup outlet 113 to the dispensing disk 6, the pushing part 23 can separate the reaction vessel 5 from the dispensing disk 6 into the first channel 213, and the pushing part 23 can push the reaction vessel 5 to move in the extending direction of the first channel 213. The reaction vessel 5 rotated to the cup discarding station 1d is opposed to the through opening 113 so that the extending directions of the reaction vessel 5 and the first channel 213 are aligned, and the pushing portion 23 can smoothly disengage the reaction vessel 5 from the opening 611 of the dispensing disk 6 in the radial direction of the body 1 by only abutting at least a part of the reaction vessel 5 and applying a force in a direction away from the axis of the body 1, and directly enter the first channel 213 with the pushing of the pushing portion 23. The matching structure is simple, the reaction container 5 is convenient to push, and the work of abandoning the reaction container 5 from the first channel 213 to the collecting device can be well completed.

In an alternative embodiment, the matching assembly 221 includes a guide rail 221a and a sliding block 221b, the guide rail 221a extends along the radial direction of the body 1, the pushing portion 23 is connected to the sliding block 221b, and the sliding block 221b can move the pushing portion 23 along the extending direction of the first channel 213 along the movement of the guide rail 221 a. Through the arrangement of the guide rail 221a and the slide block 221b which are matched with each other, the power provided by the driving assembly 222 is converted into the sliding of the slide block 221b relative to the guide rail 221a, so that the movement precision of the slide block 221b relative to the guide rail 221a can be better controlled, the precision of controlling the displacement of the pushing part 23 is further improved, the pushing part 23 can be favorable for accurately separating the reaction container 5 from the dispensing disc 6 and pushing the reaction container 5 to the first channel 213, the abandoning work of the reaction container 5 can be smoothly realized, and the reaction container 5 is prevented from being stacked in the first channel 213.

The driving assembly 222 includes a driving motor 222a and a synchronous pulley set, the synchronous pulley set includes a first synchronous pulley 222b, a second synchronous pulley 222c and a second synchronous belt connecting the first synchronous pulley 222b and the second synchronous pulley, the first synchronous pulley 222b is connected to an output shaft of the driving motor 222a, the second synchronous pulley 222c is connected to the mounting bracket 211, the sliding block 221b is connected to the second synchronous belt, a plane formed by a connection line between an axis of the first synchronous pulley 222b and an axis of the second synchronous pulley 222c is parallel to an extending direction of the guide rail 221a, and the driving motor 222a can drive the first synchronous pulley 222b to rotate, so that the second synchronous belt is matched to drive the sliding block 221b to slide along the guide rail 221 a. Through the synchronous belt group connected with the output shaft of the driving motor 222a, the rotation of the driving motor 222a is converted into the motion of the synchronous belt, the motion speed of the synchronous belt is far lower than the rotation speed of the driving motor 222a, and compared with the situation that the motion of the sliding block 221b is controlled by directly controlling the driving motor 222a to start or stop rotating, the motion precision of the sliding block 221b is controlled to be higher by controlling the motion of the synchronous belt, so that the higher motion precision of the pushing part 23 is ensured, and the situations of under-motion or over-motion and the like of the pushing part 23 are avoided.

Optionally, the second driving portion 22 further includes a limiting component, the limiting component is configured to limit the movement of the sliding block 221b, the limiting component includes a stroke block 221c and a stroke control, the stroke block 221c is connected to the sliding block 221b, and the stroke control is respectively located at two sides of the stroke block 221c along the extending direction of the guide rail 221 a. When the sliding block 221c moves along the guide rail 221a, through the matching of the set stroke control and the stroke block 221c, the sliding block 221b can be prevented from driving the pushing part 23 to move excessively when the driving component 222 fails, the movement of the pushing part 23 is limited to a limited range to reciprocate, and the stability and the precision of the movement of the pushing part 23 are improved. The set stroke control may be a butting block for limiting the movement of the sliding block 221c by butting the stroke block 221c and the butting block, or may be a photosensitive automatic control structure such as an optical coupler for limiting the sliding block 221c, and the relative distance of the stroke block 221c is measured by light formed by the optical coupler 3. Or other stroke control capable of realizing limit may also be set, and is not limited specifically herein.

Specifically, the mounting bracket 21 includes a mounting seat 212 and a mounting plate 211 disposed thereon, the mounting seat 212 is connected to one side of the body 1, the mounting plate 211 extends along a radial direction of the body 1 and partially protrudes out of the mounting seat 212 to above the body 1, the second driving portion 22 is disposed on the mounting plate 211, the first channel 213 is disposed on the mounting seat 212, the mounting plate 211 is provided with a moving channel 211a, the moving channel 211a is communicated with the first channel 213, and the pushing portion 23 at least partially penetrates through the moving channel 211 a. By arranging the mounting plate 211 and the mounting seat 212 in a matching manner, the second driving unit 22 can drive the pushing unit 23 to push the reaction vessel 5 out of the dispensing disc 6 during the reciprocating movement, and drive the pushed reaction vessel 5 to enter the first channel 213 and push the reaction vessel 5 to a fixed collection position along the first channel 213 to complete the cup discarding operation, so as to prevent the reaction vessel 5 from being accumulated in the first channel 213 or not being separated from the dispensing disc 6.

It is understood that the fitting plate 211 and the fitting seat 212 are engaged with each other in order to achieve good engagement between the second driving unit 22, the pushing unit 23, the dispensing disk 6, the reaction vessels 5 thereon, and the first channel 213, and to stably push the reaction vessels 5 to the collection position without accumulating in the first channel 213. For the disposable cup assembly 2, the specific structural cooperation between the parts can be, for example: the mounting seat 212 is arranged at a side portion of the body 1 corresponding to the cup discarding station 1d, a first channel 213 extending along the radial direction of the body 1 is arranged at one side of the mounting seat 212 facing the body 1, the first channel 213 extends into the accommodating cavity 111 through the cup outlet 113 to be in clearance fit with the internal dispensing disc 6, and when the reaction vessel 5 rotates to the cup discarding station 1d along with the dispensing disc 6, the opening 611 of the accommodating position 61 provided with the reaction vessel 5 is opposite to the first channel 213. The portion of the mounting plate 211 above the mounting seat 212 extends at least above the dispensing disc 6 corresponding to the reaction vessel 5 along the radial direction of the body 1, so that when the slide block 221c drives the pushing portion 23 to move, the pushing portion 23 can move at least above the receiving position 61, and push the reaction vessel 5 to be ejected and enter the first channel 213 after the pushing portion 23 abuts against the side of the reaction vessel 5 away from the opening 611. The pushing portion 23 is disposed above the reaction container 5, so that the stability and strength of the force applied to the reaction container 5 can be improved, and the extending length of the corresponding guide rail 221a, the specific positions of the limiting component relatively disposed on the two sides of the sliding block 221c, the specific arrangement positions of the two synchronous pulleys in the driving component 222, the extending length and position of the moving channel 211a along the radial direction of the body 1, and the like can be adaptively adjusted according to the setting of the pushing portion 23, which is not specifically limited herein.

When the reaction container 5 is rotated to be located at the cup discarding position 1d, since the reaction container 5 is a cup body structure having the container shoulder 52 therein, in order to enable the pushing portion 23 to have a good cup pushing effect on the reaction container 5, the reaction container 5 can be rapidly and stably released from the opening 611 to the first channel 213 along the radial direction of the body 1. The pushing portion 23 includes a dial 232 and a base 231 connecting the dial 232 to the sliding block 221b, the dial 232 passes through the moving channel 211a, the dial 232 has an abutment surface 232a, and the abutment surface 232a is used for abutting against the sidewall of the container shoulder 52 to push the reaction container 5 to move. Before the reaction container 5 reaches the cup discarding station 1d, the shifting block 232 can move to a position above the cup discarding station 1d corresponding to the accommodating position 61 in advance, and at least part of the shifting block 232 is located on one side of the accommodating position 61 far away from the second driving part 22, so that when the reaction container 5 reaches the cup discarding station 1d, one side of the reaction container 5 far away from the opening 611 can be abutted against the abutting surface 232a, and the reaction container 5 can be driven to be separated from the dispensing disc 6 by the movement of the shifting block 232 towards the side close to the opening 611.

Optionally, when the shifting block 232 is engaged with the reaction vessel 5 having the vessel shoulder 52 to push the reaction vessel to be separated from the dispensing disc 6, a surface of the shifting block 232 facing a side of the first channel 213 is provided with a recess 232b, so that the shifting block 232 forms two opposite convex structures along a radial direction of the body 1, and the abutting surface 232a is provided on at least one opposite side wall of the convex structure. When the cuvette assembly 2 is in operation, at least part of the container shoulder 52 of the reaction container 5 is located in the recess 232b, and the abutment surface 232a corresponds to the reaction container 5 in the radial direction of the body 1. When the drive paddle 232 moves to separate the reaction vessel 5 from the dispensing tray 6, at least the abutment surface 232a on the side away from the opening 611 abuts the reaction vessel 5 and pushes the reaction vessel 5 to move in the radial direction to enter the first path 213.

With the paddle 232 provided, the surface thereof on the side facing the first channel 213 may be flush with or clearance-fitted to the lower surface of the cell shoulder 52 when the reaction cell 5 is placed on the dispensing disk 6. When the two are in clearance fit, the surface of the side of the dial 232 facing the first channel 213 is above the lower surface of the container shoulder 52 as seen in the height direction of the incubation unit, and the clearance between the two surfaces is no more than half the height of the container shoulder 52.

In an alternative embodiment, the pushing portion 23 may also be configured as two clamping blocks that can approach or separate from each other along the radial direction of the body 1, the movement of the two clamping blocks that approach or separate from each other can be controlled by the driving member, before the reaction vessel 5 enters the cup discarding station 1d, the pushing portion 23 is located above the dispensing disc 6, and the two clamping blocks are respectively located at two sides of the reaction vessel 5 to be entered, after the reaction vessel 5 enters the cup discarding station 1d, the two clamping blocks can be controlled to clamp the reaction vessel 5, and then the reaction vessel 5 can be conveniently and rapidly separated from the dispensing disc 6 into the first channel 213 by the control of the second driving portion 222, the structural matching stability of the pushing portion 23 is good, and the reaction vessel 5 can be accurately put into the collection position from the first channel 213. Other configurations of the pushing portion 23 may be provided to ensure that the reaction vessels 5 are pushed to the collection position, so as to avoid accumulation in the channel, not to mention here.

In one embodiment, the first channel 213 includes a first sub-channel 213a and a second sub-channel 213c connected to each other along the extending direction of the first channel 213, the first sub-channel 213a is located above the second sub-channel 213c, and the width of the first sub-channel 213a is greater than the width of the second sub-channel 213c, so that a stepped surface 213b is formed therebetween, and the stepped surface 213b is flush with or clearance-fitted to the surface of the paddle 232 close to the first channel 213 along the height direction of the incubation unit. With the first sub-passage 213a and the second sub-passage 213c provided, the shape of the cross section thereof in the extending direction of the first passage 213 is adapted to the shape of the reaction vessel 5, and the width of the second sub-passage 213c is not less than the diameter of the vessel body 51 and less than the width of the vessel shoulder, and not more than 5mm of the diameter of the vessel body 51 at most. The width of the first sub-passage 213a is greater than the diameter of the container shoulder 52. The design of the first sub-channel 213a and the second sub-channel 213c enables the reaction vessel 5 to be limited in the channel with limited space when the pushing part 23 pushes the reaction vessel 5 into the first channel 213, and the lower surface of the vessel shoulder 52 in the reaction vessel 5 contacts with the stepped surface 213b, so that when the pushing part 23 pushes the reaction vessel 5 out into the first channel 213, the reaction vessel 5 can directly enter the first channel 213 along the radial direction, and the phenomenon of skewness caused by uneven force when pushing the reaction vessel 5 is avoided by means of shape matching, which results in the accumulation of the reaction vessel 5 in the first channel 213 and the inability of being pushed to a fixed collection position by the pushing part 23.

Optionally, the mounting seat 212 further includes a second channel 214 communicating with the first channel 213, the second channel 214 intersects the first channel 213, and the pushing part 23 can push the reaction vessel 5 from the first channel 213 into the second channel 214. With the second passage 214 provided for communicating with the collecting means for collecting the used reaction vessels 5, the diameter of the second passage 214 is at least larger than the height of the reaction vessels 5 so that the reaction vessels 5 can smoothly enter the collecting means from the second passage 214. The extending direction of the second channel 214 may be perpendicular to the extending direction of the first channel 213 or inclined downward at a certain angle with respect to the extending direction, as long as the reaction vessels 5 are not stacked or stuck in the second channel 214, and is not particularly limited.

It will be appreciated that the predetermined positions referred to above will be different depending on the configuration of the first channel 213, the second channel 214, etc. in the mounting base 212. For example, when the first passage 213 and the second passage 214 intersecting as described above are provided, the preset position thereof is the intersection position where the two passages intersect. The reaction container 5 is not particularly limited as long as the reaction container 5 can be pushed to a predetermined position and the reaction container 5 can directly or indirectly enter the collecting device.

It can be understood that, during the rotation of the dispensing disc 6, an in-place detection device such as an optical coupler is arranged at a position corresponding to each station, and the control unit can complete sample analysis according to the arranged in-place detection device and the combination of components in each station according to time sequence. Taking a reaction vessel 5 as an example, when the dispensing disc 6 rotates to an empty accommodating position 61 opposite to the cup inlet 112, the in-place detection device sends a signal to the control unit, and the control unit controls the third driving unit 11a to stop the operation of driving the dispensing disc 6 to rotate, and continues to rotate after the cup inlet operation is completed. The sample mixing station 1b and the detection station 1c are sequentially passed through in time sequence according to the same principle, and a detailed description is omitted. When the in-place detection device detects that the reaction vessel 5 reaches the cup discarding station 1d, the third driving part 11a is controlled to stop, in this state, the pushing part 23 in the cup discarding assembly 2 has been moved to above the accommodating position 61 in advance, when the reaction vessel 5 enters the cup discarding station 1d, two protruding structures of the shifting block 232 are arranged on two sides of the reaction vessel 5 in the extending direction of the first channel 213, and the abutting surface 232a of the shifting block 232 abuts against or is in clearance fit with the side wall of the corresponding vessel shoulder 52 of the reaction vessel 5. And the second driving part 222 is driven to drive the matching component 221 to move, so as to drive the reaction container 5 to be taken out from the opening 611 of the accommodating position 61 and enter the first channel 213 to a preset position, thereby realizing cup throwing of the reaction container 5.

In an embodiment, a position detection assembly 3 may be further included, the position detection assembly 3 including at least one detecting portion 31 at least located on the cuvette discarding assembly 2, the detecting portion 31 at least being used for detecting a position of the reaction vessel 5 moving on the cuvette discarding assembly 2. Through the detection part 31, the condition that the reaction vessel 5 moves in the cup abandoning assembly 2 can be detected at least, and whether the reaction vessel 5 is pushed to move in the cup abandoning assembly 2 at a certain time or not can be judged according to the detected result, so that the condition that the reaction vessel 5 is not pushed to the right position and is retained in the cup abandoning assembly 2 is avoided, the normal use of the incubation unit is not influenced due to the fact that the reaction vessel 5 is partially blocked during cup abandoning, and meanwhile, the problem of blocking can be solved in time by a worker to remove the fault conveniently.

Optionally, the detecting part 31 is at least located at a position corresponding to the first channel 213, and is used for detecting the position of the reaction container 5 on the first channel 213. When the detecting part 31 is disposed at a position corresponding to the first channel 213, the position of the reaction container 5 pushed by the pushing part 23 on the first channel 213 can be detected by the detecting part 31, so as to determine whether the reaction container 5 is pushed to move at a certain time without being pushed in place and being retained in the first channel 213, thereby ensuring that the normal use of the incubation unit is not affected due to local congestion of the reaction container 5 when the cup is thrown, and simultaneously being convenient for the staff to solve the congestion problem in time to remove the fault.

With the probe unit 31 provided, the probe unit 31 is located at least at a position corresponding to a side of the first lane 213 away from the dispensing disk 6 in the extending direction of the first lane 213, and the probe unit 31 is configured to detect the reaction vessel 5 passing through the position. The detecting portion 31 is disposed at a position of the first passage 213 relatively far from the body 1, so that when the reaction vessel 5 moves in the first passage 213 while the cup pushing is performed at the cup discarding position 1d, when the detecting portion 31 disposed at an end far from the body 1 can detect that the reaction vessel 5 passes through the position, it represents that the reaction vessel 5 is not jammed at the first half, so that the reaction vessel 5 can finally enter the collecting device. When the pushing portion 23 does not detect the reaction container 5 at the predetermined position during the pushing process, it is proved that the reaction container 5 is still in the first channel 213 and is not pushed into place by the pushing portion 23, which easily causes the reaction container 5 to be stacked in the first channel 213. At this time, the detection part 31 can send out an alarm signal so that the worker can timely remove the fault and avoid influencing the normal sample analysis work.

Alternatively, a plurality of detecting parts 31 may be sequentially arranged along the extending direction of the first passage 213, and the plurality of detecting parts 31 are used to detect the specific position of the reaction vessel 5 moving the first passage 213 before the reaction vessel 5 moves to the preset position along the first passage 213. In order to realize the real-time monitoring to reaction vessel 5, can learn reaction vessel 5 in this time quantum of first passageway 213 motion, the position that different time reaction vessel 5 was located to and whether leave this position at the next moment and get into next position, improve the detection effect to reaction vessel 5 position state, can in time discover the problem, avoid blocking up at first passageway 213.

When the discarding cup assembly 2 is provided with the first channel 213 and the second channel 214 communicated with each other, the second channel 214 is used for introducing the reaction vessel 5 into the collecting device, and the detecting part 31 may be provided at a position corresponding to the second channel 214 for detecting the position of the reaction vessel 5 in the second channel 214. Through the setting with the second passageway 214 corresponding position that detection portion 31 set up, detect reaction vessel 5 at this position after the time that surpasses the default at this position at this detection portion 31, then send out the warning, probably be the condition that reaction vessel 5 was filled up in the collection device and overflow to second passageway 214 appears, remind the staff in time to handle, guarantee incubation unit's normal operating, avoid filling up the collection device because the maloperation and flowing backward to first passageway 213 and cause and pile up.

It is understood that, for the detecting portion 31, it is also possible to arrange the mounting plate 211 in the cup discarding assembly 2 at a position corresponding to the pushing portion 23, and the detecting portion 31 is used for detecting the moving position of the pushing portion 23. The position of the pushing part 23 is directly detected by the detecting part 31, so that the pushing part 23 can be ensured to move in place during the reciprocating movement process, the reaction vessel 5 is pushed to a fixed position, and the reaction vessel 5 is prevented from being accumulated in the first channel 213 to cause blockage.

The detecting unit 31 itself may be a structure that is identified by light sensation, or a structure that is identified by contact, that is, the detecting unit 31 may be disposed at a position of the housing 11 corresponding to the cup discarding station 1d to detect whether the reaction vessel 5 reaches the cup discarding station 1d, and is not particularly limited herein.

In an alternative embodiment, referring to fig. 8, the probe portion 31 includes a probe 311, the discard cup assembly 2 has an alignment bore 212a communicating with the first channel 213, and the probe 311 extends at least partially into the alignment bore 212 a. The probe 311 can detect the position of the reaction vessel 5 in the first channel 213 through the alignment hole 212a, and when the reaction vessel 5 moves along the first channel 213 to a position corresponding to the probe 311, the probe 311 can sense the reaction vessel 5, thereby detecting the position of the reaction vessel 5. For example, when the probe portion 31 is provided as a mechanical fitting structure, the probe 311 has a contact surface, and when the reaction vessel 5 moves along the first passage 213, the contact surface of the probe 311 can come into contact with the reaction vessel 5, and the reaction vessel 5 can continue to move relative to the contact surface to release the contact. For another example, when the detecting unit 31 is configured to be a photoelectric sensor, the probe 311 can form a light beam to be incident on the first channel 213 through the alignment hole, and the reaction cuvette 5 can interrupt the light beam when the reaction cuvette 5 moves to the position along the first channel 213. By forming the complete light beam in the first passage 213, the reaction vessel 5 is shielded as the reaction vessel 5 passes through the position, so that the formed light beam is interrupted, thereby enabling the position of the reaction vessel 5 in the first passage 213 to be determined.

Optionally, when the detection portion 31 is set as the photoelectric sensing structure, in order to realize a better position detection effect thereof, the detection portion 31 is an optical coupler, the alignment holes 212a are symmetrically arranged on two side walls of the first channel 213, and along the extending direction perpendicular to the first channel 213, two output ends of the optical coupler are located on two symmetrical sides of the first channel 213, that is, located at the corresponding alignment holes 212a respectively, two output ends form a light beam in the first channel 213, when the reaction container 5 moves to the position, the reaction container 5 breaks the light beam and then represents the position of the reaction container 5 at this moment, and position positioning can be performed.

In an embodiment, when the reaction vessel 5 has the structure of the vessel body 51 and the vessel shoulder 52 and the first channel 213 is provided in a stepped structure including the first sub-channel 213a and the second sub-channel 213c adapted to the reaction vessel 5 having the structure, for the probe 31 provided, the alignment hole 212a for providing the probe 311 may be provided in a sidewall of at least one of the first sub-channel 213a and the second sub-channel 213c such that the alignment hole 212a penetrates at least one of the first sub-channel 213a and the second sub-channel 213 c. When the position of the aligning hole 212a is set to correspond to the position of the first sub-passage 213a, the probe 311 at least partially protruding into the aligning hole 212a is used to engage with the vessel shoulder 52 of the reaction vessel 5 to judge whether there is a pile of the reaction vessel 5 in the first passage 213 by detecting whether the vessel shoulder 52 passes through this position within a set interval time, stays at this position for more than a preset time, or the like. Similarly, when the alignment hole 212a is disposed at a position corresponding to the second sub-channel 213c, the probe 311 at least partially extending into the alignment hole 213a is used to engage with the container body 51 of the reaction container 5, which will not be described in detail herein.

In an optional embodiment, the detecting portion 31 may further include an identifying unit, and in the process that the reaction container 5 moves along the first channel 213, the detecting portion 31 may determine, according to a preset time, the number of times that the reaction container 5 passing through the position corresponding to the detecting portion 31 passes through, to determine whether there is a case that the reaction container 5 is not pushed in place when the reaction container 5 is pushed to move at a certain time, so that the number of times that the reaction container 5 actually passes through is less than the preset number of times, thereby ensuring that the normal use of the incubation unit is not affected due to local congestion of the reaction container 5 when the cup is thrown, so that a worker can timely remove a fault. For example, the identification unit may include at least one of a counter and a timer, each electrically connected to the probe 311, for limiting the number of times the reaction vessel 5 is detected within a preset time to a preset number of times, and for limiting the time the reaction vessel 5 is detected within a preset time range. The in-position detection of the reaction vessel 5 can be combined with the time sequence by providing a counter, a timer, or the like, and whether or not the reaction vessel 5 is stacked in the first channel 213 can be determined more accurately by the time interval between the reaction vessel 5 passing through the corresponding position, the number of times the reaction vessel 5 has passed through a certain period of time, the time for detecting the reaction vessel 5 while maintaining the position, or the like.

Optionally, the position detection assembly 3 may also be disposed in the detection station 1c, the sample adding and mixing station 1b, and the like, and is configured to detect whether the reaction container 5 accurately reaches the corresponding station, so as to improve the positioning accuracy, which is not specifically limited herein.

As a specific embodiment of the present application, the incubation unit includes a control portion, the control portion may include a middle computer and a lower computer, the middle computer is configured to receive a signal from the lower computer and send an instruction to the lower computer, and the lower computer is configured to execute an instruction control mechanism of the middle computer to implement a corresponding action and feed back a signal formed by the executed corresponding action to the middle computer. The lower computer may include a control unit disposed corresponding to the above-mentioned electronic components, such as the driving motor, the detector, and the detecting portion, and all the above-mentioned electronic components are connected to the control unit, so as to enable the incubation unit to sequentially implement the incubation operation, which will not be described in detail herein.

In the incubation unit, the positioning assembly 4 provided in the incubation unit can position the dispensing tray 6 in an auxiliary manner, so that the reaction vessel 5 can stop at the corresponding station with higher precision when rotating along with the dispensing tray 6. The disposal cup assembly 2 is provided to facilitate the disposal of the reaction vessel 5 to the collection means at the disposal cup station 1d with more stability and higher accuracy. The position detection assembly 3 is arranged to monitor the position of the reaction vessel 5 in the discard cup assembly 2 and avoid clogging in the discard cup assembly 2. Through the design of integrating a plurality of stations in will hatching in an organic whole for the unit of hatching has higher integrated level, can be convenient quick with reaction vessel 5 conversion to different stations, and can maintain reaction vessel 5 at suitable temperature throughout in the conversion process, with the stability and the degree of accuracy of guaranteeing to hatch the result.

The application also provides a sample analyzer, and the sample analyzer includes the incubation unit, and the incubation unit is the incubation unit described in the foregoing, and is not described herein any more.

Based on the incubation unit, the present application provides a sample analysis method, taking a reaction container 5 as an example for performing sample analysis in the incubation unit, the sample analysis method comprising:

s101, the reaction vessel 5 is loaded by the loading mechanism and enters the dispensing disc 6 from the cup entering station 1 a.

S102, the reaction container 5 enters a sample adding and mixing station 1b, and a sample is added into the reaction container 5 for mixing.

S103, after the reaction containers 5 mixed by sample adding are mixed, the reaction containers are driven by the dispensing disc 6 to move to the detection station 1c according to a time sequence, when the detection station 1c detects that the reaction containers 5 move to the detection station 1c, a detection signal is sent to the positioning assembly 4, the positioning assembly 4 receives the detection signal to control the first driving part 41 to move so that the clamping part 42 is clamped with the reaction containers 5, the detection station 1c sends a completion command to the positioning assembly 4 after detection is completed, and the first driving part 41 receives the completion command to control the clamping part 42 to be released from clamping with the reaction containers 5.

S104, the dispensing disc 6 drives the reaction vessel 5 to move continuously to the cup discarding station 1d according to the time sequence, when it is detected that the reaction vessel 5 moves to the cup discarding station 1d, the second driving part 22 is controlled to move so that the pushing part 23 drives the reaction vessel 5 to separate from the dispensing disc 6 and move to a preset position, and the detecting part 31 is at least used for detecting the position where the pushing part 23 pushes the reaction vessel 5 to arrive.

The reaction vessel 5 is loaded by the loading mechanism from the cup feed station 1a into the dispensing disk 6. The reaction container 5 enters the dispensing disc 6 from the cup inlet 112, so that the reaction container 5 enters from the opening 611 to be matched with the accommodating position 61 in the dispensing disc 6, and the rotation of the dispensing disc 6 can drive the reaction container 5 to rotate out from the cup inlet station 1a to move to the next sample mixing station. It can be understood that, in the cup entering station 1a, when the reaction vessel 5 is placed in the containing position 61, the control unit may control the dispensing disc 6 to stop at the cup entering station 1a, and after the containing position 61 opposite to the cup entering opening 112 is placed in the reaction vessel 5 through the opening 611, the dispensing disc 6 is controlled to rotate to the next placing cavity containing position 61 opposite to the cup entering opening 112, thereby implementing cup entering. Or the dispensing disc 6 may be kept in motion all the time during the whole cup entering process, and when the dispensing disc rotates to the position where the cup entering opening 112 is opposite to the placing cavity accommodating position 61, the reaction vessel 5 is rapidly placed in the placing cavity accommodating position 61 by using a time gap, so as to improve the efficiency. And is not particularly limited herein.

The reaction vessel 5 enters the sample-adding-and-mixing station 1b, and a sample is added to and mixed with the reaction vessel 5. And controlling the dispensing disc 6 to rotate according to a time sequence, and controlling the automatic or manual addition of one or more liquids from at least one through hole 121 of the top cover 12 when detecting that the reaction container 5 is driven to enter the sample adding and mixing station 1b by the rotation of the dispensing disc 6 so as to mix the added liquids in the reaction container 5 to obtain a mixed liquid. It can be understood that the device for sample addition in the sample adding and mixing station 1b can be configured as an automatic sample adding device, and the device can control sample addition to the reaction container 5 through the through hole 121 when the device can detect that the reaction container 5 moves to the position when the dispensing disk 6 rotates.

The reaction container 5 mixed by sample adding is continuously driven by the dispensing disc 6 to rotate to the detection station 1c according to the time sequence, and in the detection station 1c, a detection head or a detection ray of a detector is required to enter from the through hole to detect the mixed liquid in the opposite reaction container 5. In order to ensure the detection accuracy, when the reaction vessel 5 moves to the station, the dispensing disk 6 needs to be controlled to stop so that the vessel mouth of the reaction vessel 5 faces the through-hole. Through the locating component 4 who sets up, when detecting that reaction vessel 5 operates to detection station 1c, control locating component 4 work for joint portion 42 can realize the joint with dividing the carousel 6, with divide the carousel 6 pivoted assistance-localization real-time through joint portion 42 restriction, has improved the counterpoint precision of through-hole and reaction vessel's container mouth.

It can be understood that, for the positioning assembly 4 provided, the positioning method specifically includes: taking a reaction vessel 5 as an example, controlling the dispensing disc 6 to drive the reaction vessel 5 to rotate in time sequence, when detecting that the reaction vessel 5 moves to the detection station 1c, sending a position signal to the control unit, when receiving the position signal, the control unit sending a control command to the first driving part 41 and the third driving part 11a, respectively, after receiving the control command, the third driving part 11a, the dispensing disc 6 is controlled to stop rotating, the first driving part 41 controls the clamping part 42 to move until the clamping part 42 is clamped with at least the reaction vessel 5 positioned at the detection station 1c, and after the detection is finished, the control unit receives the detection finished signal, controls the first driving part 41 to control the clamping part 42 to move so as to release the clamping with the reaction vessel 5, at the same time, the third driving unit 11a drives the dispensing disk 6 to rotate, so that the reaction container 5 after the detection is completed continues to rotate with the dispensing disk 6 to the next station. Therefore, the positioning precision of the reaction container 5 at the detection station 1c is ensured through the auxiliary positioning of the positioning assembly 4, and the relative position of the container opening of the reaction container 5 and the through hole is ensured not to be deviated.

The separate injection disc 6 drives the reaction vessel 5 to move continuously to the cup abandoning station 1d, and when the cup abandoning assembly 2 is used for carrying out cup abandoning work on the in-place reaction vessel 5, the cup abandoning method of the cup abandoning assembly 2 specifically comprises the following steps: before the reaction container 5 is detected to move to the cup discarding position 1d, the second driving part 22 is controlled to move to drive the matching component 221 to move, so that the pushing part 23 moves to the initial position along the first channel 213 in the direction close to the dispensing disc 6, and when the reaction container 5 moves to the cup discarding position 1d, the second driving part 22 is controlled to move in the reverse direction, so that the pushing part 23 can abut against the reaction container 5 and drive the reaction container 5 to move along the first channel 213.

When throwing the cup through abandoning cup subassembly 2, be located and abandon the position detection subassembly 3 of cup subassembly 2 and be used for carrying out position detection to reaction vessel 5 at least, avoid reaction vessel 5 to block up in the passageway and influence the use of incubating the unit.

The working method specifically comprises the following steps: in the cup discarding station 1d, in the process of pushing the reaction vessel 5 to move by the cup discarding assembly 2, if the reaction vessel 5 detected by the detecting part 31 meets the preset condition, it is determined that the reaction vessel 5 is in a normal moving state in the cup discarding assembly 2. The cup abandoning assembly 2 is combined with the position detection mechanism 3, the movement of the reaction vessel 5 in the cup abandoning assembly 2 is monitored through the detection part 31, and if the detected reaction vessel 5 can be maintained under the condition that the preset conditions are met all the time, the cup abandoning work in the cup abandoning station 1d is represented to be in a normal running state. When the reaction vessel 5 detected by the detection part 31 does not satisfy the preset condition, the place where the problem occurs can be determined according to the different conditions of the specific conditions that are not satisfied detected by the detection part 31, so that the problem can be solved timely and efficiently, and the reaction vessel 5 is prevented from being blocked in the channel.

In one embodiment, the detecting portion 31 is located at a predetermined position in the first passage 213, and the cup throwing operation is completed by pushing the reaction vessel 5 to move to the predetermined position by the cup throwing assembly 2. The detection method comprises the following steps: in the cup discarding station 1d, in the process of pushing the reaction vessel 5 to move by the cup discarding assembly 2, if the reaction vessel 5 which can be detected by the detecting part 31 at every preset time reaches the preset position, it is determined that the reaction vessel 5 is in a normal moving state in the cup discarding assembly 2, or if the number of times that the reaction vessel 5 passes through the preset position, which is detected by the detecting part 31 at the preset time, is a preset number of times, it is determined that the reaction vessel 5 is in a normal moving state in the cup discarding assembly 2; otherwise, it is determined that the first channel 213 is blocked by the cup holder of the reaction vessel 5, and the detecting unit 31 sends an alarm signal to stop the operation. The detecting unit 31 provided at the predetermined position can detect and count the in-place state of the reaction container 5 moving along the first path 213.

According to the specific conditions of the rotation speed of the dispensing disc 6, the time required by the cup discarding assembly 2 when discarding the reaction containers 5, and the like, the preset data set by the identification unit in the detection part 31 is determined, and the preset data can be preset times when the reaction containers pass through the counter in a period of time, or preset time when two adjacent reaction containers 5 reach a preset position, and the preset time can be detected by a timer in the identification unit. Taking a preset number of times as an example, the number of times the reaction vessel 5 is detected by the counter is counted every 1 hour, for example. When the cup throwing assembly 2 drives the reaction container 5 to reach the preset position to complete one cup throwing operation within 1 hour in the process of cup throwing, each time the reaction container 5 is at the preset position, the reaction container can be detected by the detecting part 31 and is recorded by the timer for 1 time. After one hour, the detection times obtained by the counting of the counter are compared with the preset times, if the detection times are equal to the preset times, the cup throwing work in the cup throwing assembly 2 is normal every time, and the cup throwing assembly can continue to work to perform the detection for the next hour again. If the detection times are less than the preset times, it indicates that there may be at least one cup-throwing time when the reaction vessel 5 does not reach the preset position, and one or more subsequent reaction vessels 5 are blocked in the channel. And the detection part 31 sends out an alarm signal and controls to stop when stacking, and after the staff gets rid of the reaction container 5 blocked in the first channel 213, the system is restarted and a new round of timing detection is repeated.

In one embodiment, the detecting portion 31 is disposed at one or more positions before the preset position along the extending direction of the first channel 213, in the cup discarding station 1d, in the process of pushing the reaction vessel 5 to move by the cup discarding assembly 2, if the detecting portion 31 can detect the reaction vessel 5 at the corresponding position and the detected same reaction vessel 5 is maintained at the detected position for less than the preset time, it is determined that the reaction vessel 5 is in a normal moving state in the cup discarding assembly 2, otherwise, it is determined that the first channel 213 has a jammed cup of the reaction vessel 5, and the detecting portion 31 sends an alarm signal and controls to stop. Specifically, the timer provided in the identification unit of the detection part 31 can time the time for keeping identifying the reaction container 5, and if the discard cup assembly 2 drives the reaction container 5 to move to realize normal operation of the discard cup, the time for identifying the reaction container 5 passing through the detection part 31 each time can be set to be not more than the preset time according to the speed of the reaction container 5 moving in the first channel 213. When the time of the reaction container 5 recognized by the detection part 31 exceeds the preset time, it indicates that the reaction container 5 may be jammed or has been jammed to the position where the detection part 31 is provided, and at least one reaction container 5 is jammed in the first passage 213. The detector 31 sends an alarm signal to stop the control until the worker removes the reaction vessel 5 accumulated in the first channel 213, and then restarts the control.

In one embodiment, the detecting portion 31 is further disposed in the housing 11 or the cup discarding assembly 2 corresponding to the cup discarding station 1d for detecting the position of the reaction vessel 5 when it is rotated to the cup discarding station 1 d. Before the reaction vessel 5 is pushed to move by the discarding cup assembly 2, the detecting part 31 can detect the position where the dispensing disc 6 drives the reaction vessel 5 to move, and when the reaction vessel 5 is detected to move to the discarding cup station 1d, the detecting part 31 can send a position signal to control the dispensing disc 6 to stop. The detecting unit 31 serves as an in-position detecting means for recognizing that the reaction container 5 has reached the discard cup station 1d, and after in-position, can generate an in-position signal to be sent to the third driving unit 11a and the second driving unit 22 of the discard cup assembly 2. Upon receiving the in-position signal, the third drive unit 11a controls the dispensing disk 6 to stop moving, and the second drive unit 22 starts and controls the pusher 23 at the initial position to start the cup-throwing operation. In the process that the reaction container 5 moves along the first channel 213, the detection parts 31 arranged at different positions start to work, and if any detection part 31 in the first channel 213 or at a preset position detects that the blockage exists according to the method, an alarm signal can be sent out to control the whole cup throwing work or the sample analysis work to stop, and the cup throwing work or the sample analysis work is restarted after the fault is eliminated.

Optionally, the detecting portions 31 may also be disposed on two sides of the pushing portion 23 along the moving direction of the pushing portion 23, so as to limit the movement of the pushing portion 23, and when the second driving portion 22 is controlled to move to drive the pushing portion 23 to move, the setting of the position and the timing sequence may be implemented by the detecting portions 31 disposed on two sides of the pushing portion 23. When the pushing part 23 moves to the reaction container 5 and reaches the preset position, the detecting part 31 recognizes the position of the pushing part 23 to control and stop, and controls the second driving part 22 to move reversely according to the preset time sequence and reset after the detecting part 31 detects the pushing part 23, and after the pushing part 23 at the reset position is recognized by the corresponding detecting part 31, the in-place signal is sent out, the second driving part 22 is controlled to stop moving according to the time sequence, the third driving part 11a is started to enter the next reaction container 5 to enter the cup discarding station 1d and finish the cup discarding work, and the cycle is performed.

Similarly, the position of the detecting unit 31 disposed in the second channel 214 may also be detected in the above manner, for example, in the cup discarding station 1d, when the cup discarding assembly 2 pushes the reaction vessel 5 to move, if the detecting unit 31 can detect the reaction vessel 5 at the position corresponding to the second channel 214 and the detected same reaction vessel 5 is maintained at the detected position for less than the preset time, it is determined that the reaction vessel 5 is in a normal moving state in the cup discarding assembly 2, otherwise, it is determined that the reaction vessel 5 is stacked on the second channel 214, and the detecting unit 31 sends an alarm signal and controls to stop. In this way, the situation that the reaction container 5 is in the second channel 214 is identified and detected, and the reaction container 5 of the collecting device is prevented from flowing backwards to the second channel 214 after being filled, so that the second channel 214 is prevented from being blocked. And will not be described in detail herein.

Having described embodiments of the present application, the foregoing description is intended to be exemplary, not exhaustive, and not limited to the disclosed embodiments. Many modifications and variations will be apparent to those of ordinary skill in the art without departing from the scope and spirit of the described embodiments. The terminology used herein is chosen in order to best explain the principles of the embodiments, the practical application, or improvements made to the technology in the marketplace, or to enable others of ordinary skill in the art to understand the embodiments disclosed herein.

Claims

1. An incubation unit for a sample analyzer, comprising:

the cup abandoning station is provided with a cup abandoning assembly and a position detection assembly, the cup abandoning assembly comprises a second driving part and a pushing part which are matched, the second driving part is used for driving the pushing part to move, when the reaction container moves to the cup abandoning station, the pushing part is used for separating the reaction container from the separate injection disk and pushing the reaction container to a preset position,

2. The incubation unit of claim 1, wherein the cup feeding station, the sample adding and mixing station, the detection station and the cup discarding station are arranged circumferentially in time sequence on the body, the body is provided with a containing cavity, the dispensing disc is rotatably connected with the containing cavity,

the separated injection disk is provided with a plurality of containing positions along the circumferential direction, and the containing positions are used for placing the reaction containers.

3. The incubation unit of claim 2, wherein there is a fit clearance between the reaction vessel and the receiving site,

the separated injection disk drives the reaction container to rotate to the detection station, and the clamping portion moves to the position where the reaction container is clamped to limit the relative movement of the reaction container and the containing position.

4. The incubation unit according to claim 2, wherein the clamping portion comprises a clamping block provided with a clamping groove, the clamping block is connected with the output end of the first driving portion and can drive the clamping block to move along the radial direction of the body until the clamping groove abuts against the reaction container.

5. The incubation unit of claim 2, wherein the discard cup assembly further comprises a mounting bracket provided with a first channel communicating with the receiving cavity corresponding to the discard cup station, the second driving part being mounted to the mounting bracket,

the second driving part comprises a driving assembly and a matching assembly, the pushing part is connected with the matching assembly, and the matching assembly is used for driving the pushing part to move, so that the pushing part can push the reaction container to move to the preset position along the first channel.

6. The incubation unit of claim 5, wherein the detection portion is connected to at least the first channel,

when the pushing part pushes the reaction container to move along the first channel, the detection part can detect the position of the reaction container on the first channel.

7. The incubation unit of claim 6, wherein the detection portion is capable of detecting whether the reaction vessel reaches or passes the predetermined position.

8. The incubation unit of claim 7, wherein the detection portion comprises an identification unit for identifying at least the number of times the reaction vessel reaches or is in the preset position.

9. An incubation unit according to any of claims 1-8, wherein the body comprises:

a housing having an open end;

an incubation tray within the housing, at least the positioning assembly being coupled to the incubation tray;

a top cover which covers the opening end and is detachably connected with the shell,

the position of the top cover corresponding to the sample adding and mixing station is provided with at least one through hole;

and the heat insulation layer covers at least one side of the top cover, and the through hole penetrates through the heat insulation layer.

10. A sample analyzer comprising an incubation unit according to any of claims 1-9.