CN216979091U - Integrated reaction detection tube - Google Patents

Abstract

The utility model discloses an integrated reaction detection tube, which comprises a tube body and a tube cover, wherein a first cavity for placing a test strip is arranged in the tube body, the top surface of the first cavity is provided with a first opening for the test strip to pass through, a fixed plug is arranged on the first opening, and a abdicating groove matched with the first end of the test strip is arranged on the fixed plug. The utility model also discloses a packaging method and a using method of the integrated reaction detection tube. According to the integrated reaction detection tube, the first cavity is arranged for placing the test strip, the fixing plug is arranged on the first opening of the first cavity, the fixing plug can play a role in positioning the first end of the test strip, in addition, in the inversion process of the detection tube, splashed liquid reagents can be effectively prevented from entering the first cavity, the splashed liquid reagents are further prevented from polluting an NC (numerical control) membrane of the test strip, and the success rate of chromatography detection can be effectively improved.

Description

Integrated reaction detection tube

Technical Field

The utility model belongs to the technical field of immunochromatography detection, and particularly relates to an integrated reaction detection tube.

Background

The immunochromatography detection technology is to use antigen-antibody immunological reaction and chromatography reaction and take the form of dry plate test paper to achieve the purpose of fast and accurately developing color to detect the object to be detected. Generally, a sample for diagnosis or detection usually has some risks, such as toxicity and infectivity, and not only needs to pay attention to sample leakage during sample processing and detection, but also the used test tube should be treated as medical waste, especially for infectious disease detection items, such as influenza a, influenza b, respiratory syncytial virus, novel coronavirus and rotavirus, etc., during sample processing, if sample leakage is caused by misoperation or improper treatment of the used test tube causes a great risk to cause biological safety problems. Therefore, an integrated reaction tube integrating sample collection, sample treatment and detection is urgently needed to be introduced, all operations of contacting samples are concentrated in an integrally closed reagent tube, the life safety of operators is guaranteed to the greatest extent, and meanwhile, the operation convenience is improved. At present, integrated reaction tube products are available on the market, and although the existing products can meet the use requirements to a certain extent, the following defects still exist:

1) when the detection tube is inverted, the liquid medicament mixed with the sample to be detected flows rapidly under the action of gravity, so that the gravitational potential energy of the liquid medicament is converted into kinetic energy, and the liquid medicament splashes under the action of the kinetic energy, so that the liquid medicament contacts an NC (numerical control) membrane of the test strip, and chromatography detection fails;

2) after the detection tube is inverted, the test strip is in a completely sealed environment, and the internal vacuum can influence the chromatography detection effect.

Disclosure of Invention

In view of this, the present invention provides an integrated reaction detecting tube, which can effectively improve the success rate of chromatographic detection.

In order to achieve the purpose, the utility model provides the following technical scheme:

the utility model firstly provides an integrated reaction detection tube, which comprises a tube body and a tube cover, wherein at least one first cavity for placing a test strip is arranged in the tube body, the top surface of the first cavity is provided with a first opening for the test strip to pass through, a fixed plug is arranged on the first opening, and a abdication groove matched with a first end of the test strip is arranged on the fixed plug.

Furthermore, the side wall of the first cavity is provided with a pressing rib for positioning the second end of the test strip.

Furthermore, a guide inclined plane for guiding the test strip is arranged at the top of the pressing rib.

Furthermore, a result observation area is arranged on the side wall of the first cavity, and a highlight convex surface is arranged in the result observation area.

Furthermore, air holes are formed in the first cavity.

Further, the air holes are formed in the bottom surface of the first cavity.

Further, be equipped with the second cavity that is used for depositing liquid medicament in the body, be equipped with the second opening on the top surface of second cavity.

Furthermore, ribs which are convenient for eluting the sample on the swab are arranged on the side wall of the second cavity.

Further, the bottom of second cavity is equipped with the closing-in section, the internal diameter of closing-in section reduces along the orientation from last to bottom gradually, just the bottom of closing-in section is equipped with the ripples point of moulding plastics.

Further, the second cavity comprises a lower cavity positioned at the lower part and a transition section positioned at the upper part, the second opening is square, and the inner wall of the lower cavity is cylindrical; the transition section is used for enabling the second opening and the lower cavity to be smoothly connected.

Further, be equipped with bottom surface open-ended lid groove in the tube cap, the notch in lid groove forms the flap, the tube cap lid is in the upper end of body, and the tube cap with form between the body and be used for the intercommunication the third cavity of first cavity and second cavity.

Furthermore, a limiting convex rib for limiting the pipe cover is arranged on the outer wall of the pipe body, the limiting convex rib divides the pipe body into an upper part and a lower part, and the pipe cover covers the upper part of the pipe body; the axial length of the upper part of the pipe body is smaller than the depth of the cover groove.

Further, a sealing structure is arranged between the pipe body and the pipe cover; the sealing structure adopts a sealing rib arranged between the pipe cover and the limiting convex rib; the sealing rib is arranged on the bottom surface of the pipe cover, or the sealing rib is arranged on the upper side surface of the limiting convex rib.

Furthermore, a reducing section which is in interference fit with the pipe cover is arranged at the position, close to the limiting convex rib, of the upper part of the pipe body; the figures of the sections of any two planes which are parallel to each other and vertical to the axis of the pipe body on the reducing section are similar, and the geometrical size of the section of the lower plane is larger than that of the section of the upper plane.

Further, a sealing structure is arranged between the pipe body and the pipe cover; the sealing structure comprises a sealing convex rib and a sealing groove which are matched with each other; the sealing convex rib is arranged on the outer wall of the upper part of the pipe body, and the sealing groove is arranged on the side wall of the cover groove; or the sealing groove is arranged on the outer wall of the upper part of the pipe body, and the sealing convex rib is arranged on the side wall of the cover groove.

Furthermore, a positioning structure is arranged between the tube body and the tube cover.

Further, the positioning structure comprises positioning bulges and positioning grooves which are arranged in one-to-one correspondence with the positioning bulges; the positioning protrusion is arranged on the outer wall of the upper part of the pipe body, and the positioning groove is arranged on the side wall of the cover groove; or, the positioning groove is arranged on the outer wall of the upper part of the pipe body, and the positioning bulge is arranged on the side wall of the cover groove.

Further, a sealing structure is arranged between the pipe body and the pipe cover, and the sealing structure comprises a sealing convex rib and a sealing groove which are matched with each other;

the side wall of the cover groove comprises an upper side wall section and a lower side wall section, the upper side wall section is located at the upper part, the lower side wall section is located at the lower part, the geometric dimension of the lower side wall section is larger than that of the upper side wall section, the positioning protrusion or the positioning groove is arranged on the lower side wall section, and the sealing convex rib or the sealing groove is arranged on the upper side wall section.

Further, the groove bottom of the cover groove is provided with a pipe cover bulge which is downwards bulged to reduce the volume of the third cavity.

The utility model has the beneficial effects that:

according to the integrated reaction detection tube, the first cavity is arranged for placing the test strip, the fixing plug is arranged on the first opening of the first cavity, the fixing plug can play a role in positioning the first end of the test strip, in addition, in the inversion process of the detection tube, splashed liquid reagents can be effectively prevented from entering the first cavity, the splashed liquid reagents are further prevented from polluting an NC (numerical control) membrane of the test strip, and the success rate of chromatography detection can be effectively improved.

The preferable scheme of the utility model also has the following technical effects:

1) the pressing rib is arranged, so that the second end of the test strip can be positioned, the test strip is prevented from shaking, and the test strip is attached to the side wall of the first cavity to improve the chromatography effect; under the guiding action of the guide inclined plane, the test strip can be easily placed at the designated position of the first cavity;

2) by arranging the air holes in the first cavity, the test strip can be positioned in the environment with the same pressure as the outside after the detection tube is inverted, and the chromatographic detection effect can be effectively improved; in addition, in the production process, the defects of product perforation and the like caused by the fact that the rubber is punched and bent into the die can be avoided, and the qualified rate of product production is obviously increased;

3) the second cavity is used for storing the liquid reagent, and the ribs are arranged on the side wall of the second cavity, so that the scraping effect of the ribs on the swab is utilized, the sample on the swab is conveniently eluted, and the sample elution rate is improved;

4) the bottom of the second cavity is provided with the closing section, and the bottom of the closing section is provided with the injection molding wave point, so that the bottom of the second cavity can be thickened, and the glue feeding of the mold can be ensured in the production process;

5) the transition section is arranged to enable the second opening and the lower cavity to be in smooth transition, so that liquid can be prevented from being hung at the position of the second opening, and packaging is facilitated;

6) the limiting convex ribs are arranged on the outer wall of the pipe body, so that the depth of the pipe cover on the pipe body can be limited, and the distance between the bottom of the cover groove and the top surface of the pipe body is ensured; meanwhile, a sealing rib can be arranged between the limiting convex rib and the bottom surface of the tube cap to play a role in sealing, so that liquid medicament is prevented from leaking in the inversion process of the detection tube; the reducer section is arranged on the upper part of the pipe body and is in interference fit with the pipe cover, so that the binding force between the pipe cover and the pipe body is ensured;

7) of course, the sealing structure can also be a sealing convex rib and a sealing groove which are arranged between the pipe body and the pipe cover; meanwhile, a positioning structure can be arranged between the pipe body and the pipe cover, and the positioning structure comprises a positioning bulge and a positioning groove; in order to enable the pipe cover to be covered into the pipe body and the pipe cover to be taken down from the pipe body more conveniently, the side wall of the cover groove is divided into two sections, the geometric dimension of the lower section of the side wall is larger than that of the upper end of the side wall, the positioning structure is arranged on the lower section of the side wall, and the sealing structure is arranged on the upper section of the side wall, so that when the pipe cover is covered into the pipe body, the lower section of the side wall can be easily positioned through the sealing structure arranged on the upper part of the pipe body by utilizing the positioning structure, and meanwhile, the sealing structure between the pipe cover and the pipe body is just matched together; when the pipe cover is taken down from the pipe body, the lower section of the side wall can easily pass through the sealing structure arranged at the upper part of the pipe body and be taken down smoothly after overcoming the structural force of the positioning structure and the sealing structure;

8) the bottom of the cover groove is provided with a pipe cover bulge, so that the volume of the third cavity can be reduced, and the requirement on the using amount of the liquid medicament is reduced.

Drawings

In order to make the object, technical scheme and beneficial effect of the utility model more clear, the utility model provides the following drawings for explanation:

FIG. 1 is a schematic structural view of an integrated reaction detecting tube of the present invention in example 1;

FIG. 2 is an isometric view of FIG. 1;

FIG. 3 is a lower isometric view of FIG. 1;

FIG. 4 is a schematic structural view of the tube body according to the present embodiment;

FIG. 5 is a perspective view of the tube body of the present embodiment;

FIG. 6 is a schematic view of the tube cap of the present embodiment;

FIG. 7 is a perspective view of the tube cover of the present embodiment;

FIG. 8 is a schematic structural view of the fixing plug of the present embodiment;

FIG. 9 is an exploded view of the integrated reaction detector tube of this embodiment;

FIG. 10 is a schematic diagram of a test strip;

FIG. 11 is a schematic structural view of an integrated reaction detecting tube of example 2 of the present invention;

FIG. 12 is an exploded view of the integrated reaction detector tube of this embodiment;

fig. 13 is a schematic structural view of the tube cap of the present embodiment.

Description of reference numerals:

1-test paper strip; 2-a first end; 3-NC film; 4-a second end;

10-a pipe body; 10 a-the upper part of the pipe body; 10 b-the lower part of the pipe body; 11-a first cavity; 12-a first opening; 13-a fixed plug; 14-a yielding slot; 15-ribbing; 16-a guide ramp; 17-result observation zone; 18-air holes; 19-a second cavity; 19 a-lower chamber; 19 b-a transition section; 20-a second opening; 21-ribs; 22-a closing section; 23-injection molding of a wave point; 24-limit ribs; 25-sealing convex ribs; 26-positioning projections; 27-a reducing section;

30-a tube cap; 31-cover slot; 31 a-upper side wall portion; 31 b-lower part of side wall; 32-cover opening; 33-a third cavity; 34-sealing the groove; 35-a positioning groove; 36-tube cover projection; 37-sealing rib.

Detailed Description

The present invention is further described with reference to the following drawings and specific examples so that those skilled in the art can better understand the present invention and can practice the present invention, but the examples are not intended to limit the present invention.

Example 1

FIG. 1 is a schematic view showing the structure of an integrated reaction detecting tube of example 1 of the present invention. The integrated reaction detection tube of this embodiment, including body 10 and tube cap 30, be equipped with at least one first cavity 11 that is used for placing test paper strip 1 in the body 10, the top surface of first cavity 11 is equipped with the first opening 12 that is used for test paper strip 1 to pass through, and installs fixed stopper 13 on the first opening 12, is equipped with the groove 14 of stepping down that matches with the first end 2 of test paper strip 1 on the fixed stopper 13. The integrated form reaction detection tube of this embodiment places test paper strip 1 through setting up first cavity 11 to set up fixed plug 13 on first opening 12 of first cavity 11, fixed plug 13 not only can play the effect of the first end of location test paper strip 1, invert the in-process at the test tube moreover, can effectively prevent that the liquid reagent that splashes from entering into first cavity 11 in, and then avoid the liquid reagent pollution test paper strip that splashes, can effectively improve the success rate that the chromatography detected. The pipe body 10 of this embodiment is provided with a first cavity 11 therein, and during use, a test strip 1 can be placed in the first cavity 11 to realize the detection of a single item, and at least two test strips 1 can also be placed in the first cavity 11 at the same time to realize the synchronous detection of two or more items. Certainly, in other embodiments, two or more first cavities 11 may be disposed in the tube 10, and at this time, the test strip may be selectively placed in different first cavities 11 to implement synchronous detection of multiple items.

Furthermore, a rib 15 for positioning the second end 4 of the test strip 1 is disposed on the side wall of the first cavity 11. Through setting up the rib 15, can fix a position second end 4 of test paper strip 1, prevent that test paper strip 1 from rocking to make test paper strip 1 paste on the lateral wall of first cavity 11 with heightening the chromatography effect, as shown in fig. 4. Preferably, the top of the rib 15 is provided with a guide inclined plane 16 for guiding the test strip 1, so that the test strip 1 can be easily placed at a specific position of the first cavity 11 under the guiding action of the guide inclined plane 16.

Further, as shown in fig. 2, a result observation area 17 is disposed on the sidewall of the first cavity 11, and a highlight convex surface is disposed in the result observation area 17, so as to facilitate reading of the detection result.

Further, as shown in fig. 3, a vent hole 18 is formed in the first cavity 11, and after the detection tube is inverted, the test strip 1 can be placed in the same pressure environment as the outside, so that the chromatographic detection effect can be effectively improved. The airing hole 18 of the present embodiment is provided on the bottom surface of the first cavity 11. In the production process, the defects of product perforation and the like caused by the fact that the rubber is punched and bent into the die can be avoided, and the requirement of die stripping can be met.

Further, as shown in fig. 4, a second cavity 19 for storing the liquid medicine is provided in the tube 10, and a second opening 20 is provided on a top surface of the second cavity 19. Be equipped with the rib 21 of being convenient for elute the sample on the swab on the lateral wall of second cavity 19 of this embodiment, utilize the scraping effect of rib 21 to the swab, the sample on the elution swab of being convenient for improves sample elution rate.

Further, as shown in fig. 4, a closing section 22 is disposed at the bottom of the second cavity 19, an inner diameter of the closing section 22 gradually decreases along a direction from top to bottom, and an injection molding wave point 23 is disposed at the bottom of the closing section 22. Set up the binding off section through the bottom at the second cavity to set up the ripples point of moulding plastics in the bottom of binding off section, so, can make the bottom of second cavity thick, in process of production, advance gluey with the assurance mould.

Further, as shown in fig. 6, a cover groove 31 with an open bottom is formed in the tube cover 30 of the present embodiment, a notch of the cover groove 31 forms a cover opening 32, the tube cover 30 covers the upper end of the tube body 10, and a third cavity 33 for communicating the first cavity 11 and the second cavity 19 is formed between the tube cover 30 and the tube body 10.

As shown in fig. 5, the outer wall of the tube body 10 of the present embodiment is provided with a limiting rib 24 for limiting the tube cover 30, the limiting rib 24 divides the tube body into an upper tube body part 10a and a lower tube body part 10b, and the tube cover 30 covers the upper tube body part 10 a; the axial length of the upper portion 10a of the tube body is smaller than the depth of the cover groove 31, so that after the tube cover 30 is covered on the upper portion 10a of the tube body, under the limiting action of the limiting convex rib 24, a gap is formed between the bottom of the cover groove 31 and the top surface of the tube body 10, and a third cavity 33 is formed.

Further, a sealing structure is provided between the tube body 10 and the tube cover 30 in the present embodiment. The sealing structure of the present embodiment includes the sealing rib 25 and the sealing groove 34 that are fitted to each other. Specifically, the sealing structure may be such that the sealing rib 25 is disposed on the outer wall of the upper portion 10a of the tube body, and the sealing groove 34 is disposed on the side wall of the cover groove 31; the sealing structure may also be such that the sealing groove 34 is provided on the outer wall of the upper body portion 10a and the sealing rib 25 is provided on the side wall of the cover groove 31. The sealing rib 25 of the present embodiment is provided on the outer wall of the upper portion 10a of the tube body, and the sealing groove 34 is provided on the sidewall of the cap groove 31.

Further, a positioning structure is disposed between the tube 10 and the tube cover 30. The positioning structure of the present embodiment includes positioning protrusions 26 and positioning grooves 35 provided in one-to-one correspondence with the positioning protrusions 26. Specifically, the positioning structure may be that the positioning protrusion 26 is disposed on the outer wall of the upper portion 10a of the tube body, and the positioning groove 35 is disposed on the side wall of the cover groove 31; the positioning structure may also be such that the positioning groove 35 is provided on the outer wall of the tube body upper portion 10a and the positioning projection 26 is provided on the side wall of the cover groove 31. The positioning projection 26 of the present embodiment is provided on the outer wall of the upper portion 10a of the tube body, and the positioning groove 35 is provided on the side wall of the cover groove 31.

The sidewall of the cover groove 31 of the present embodiment includes an upper sidewall section 31a at the upper portion and a lower sidewall section 31b at the lower portion, the lower sidewall section 31b has a geometry larger than that of the upper sidewall section 31a, the positioning projection 26 or the positioning groove 35 is provided on the lower sidewall section 31b, and the sealing bead 25 or the sealing groove 34 is provided on the upper sidewall section 31 a. In this embodiment, the positioning projection 26 is provided on the sidewall lower section 31b, and the sealing bead 25 is provided on the sidewall upper section 31 a.

Further, as shown in fig. 6, the bottom of the cover groove 31 is provided with a tube cover protrusion 36 protruding downward to reduce the volume of the third cavity 33, so as to reduce the requirement for the usage amount of the liquid medicament.

The following describes in detail an embodiment of the method for packaging an integrated reaction detector according to the present invention with reference to the above-mentioned embodiment of the integrated reaction detector of the present embodiment.

The method for packaging the integrated reaction detection tube comprises the following steps:

1) after the liquid medicine is injected into the second cavity 19, a sealing film is attached to the second opening 20; then, the test strip 1 is placed in the first cavity 11, and the first end 4 of the test strip 1 extends out of the first opening;

2) the cap 30 is put on the tube body 10.

Preferably, a desiccant is placed in the third cavity 33 before the tube cover 30 is placed over the tube 10 to keep the tube dry.

Preferably, after the test strip 1 is placed in the first cavity 11, a fixing plug 13 is mounted on the first opening 12. Play the effect of the first end of location test paper strip 1, invert the in-process at the test tube moreover, can effectively prevent that the liquid reagent that splashes from entering into first cavity 11, and then avoid the liquid reagent that splashes to pollute NC membrane 3 of test paper strip, can effectively improve the success rate of chromatography detection.

The following describes in detail a specific embodiment of the method of using the integrated reaction detector of the present invention with reference to the above-mentioned specific embodiment of the integrated reaction detector of the present example.

In the using method of the integrated reaction detection tube of this embodiment, specifically, in the detection tube of this embodiment, the test strip 1 is placed in the first cavity 11, the liquid medicament is placed in the second cavity 19, and the sealing film is attached to the second opening 20. Specifically, the application method of the integrated reaction detection tube of the embodiment includes the following steps:

the method comprises the following steps: the tube cover 30 is taken off from the tube body 10, and the sealing film on the second opening 20 is torn off; specifically, when the desiccant is placed in the third cavity 33, after the tube cover 30 is removed from the tube body 10, the desiccant is removed, and then the sealing film on the second opening 20 is torn off;

step two: extending the sampling swab into the second cavity 19, mixing the sample to be detected with the liquid medicament, breaking the sampling swab and leaving the broken sampling swab in the second cavity 19;

step three: covering the tube body 10 with the tube cover 30;

step four: inverting the integrated reaction detection tube of this embodiment to allow the liquid reagent mixed with the sample to be detected to contact the first end 2 of the test strip 1 through the third cavity 33;

step five: the test result was observed by the test strip 1.

The embodiment further provides an application method of the integrated reaction detection tube, and the integrated reaction detection tube of the embodiment can be applied to immunochromatography detection of novel coronavirus, influenza a, influenza b, respiratory syncytial virus or rotavirus adenovirus.

Example 2

FIG. 11 is a schematic view showing the structure of an integrated reaction detecting tube of example 2 of the present invention. The integrated reaction detection tube of the embodiment comprises a tube body 10 and a tube cap 30, wherein at least one first cavity 11 for placing the test strip 1 is arranged in the tube body 10, a first opening 12 for the test strip 1 to pass through is arranged on the top surface of the first cavity 11, a fixing plug 13 (not shown in the figure) is arranged on the first opening 12, and a yielding groove 14 matched with the first end 2 of the test strip 1 is arranged on the fixing plug 13. The integrated form reaction detection tube of this embodiment places test paper strip 1 through setting up first cavity 11 to set up fixed plug 13 on first opening 12 of first cavity 11, fixed plug 13 not only can play the effect of the first end of location test paper strip 1, invert the in-process at the test tube moreover, can effectively prevent that the liquid reagent that splashes from entering into first cavity 11, and then avoid the liquid reagent pollution NC membrane 3 of test paper strip that splashes, can effectively improve the success rate that the chromatography detected. The pipe body 10 of this embodiment is provided with a first cavity 11 therein, and during use, a test strip 1 can be placed in the first cavity 11 to realize the detection of a single item, and at least two test strips 1 can also be placed in the first cavity 11 at the same time to realize the synchronous detection of two or more items. Certainly, in other embodiments, two or more first cavities 11 may be disposed in the tube 10, and at this time, the test strip may be selectively placed in different first cavities 11 to implement synchronous detection of multiple items.

Further, as shown in fig. 11, a pressing rib 15 for positioning the second end 4 of the test strip 1 is disposed on a side wall of the first cavity 11. Through setting up the muscle 15, can fix a position the second end 4 of test paper strip 1, prevent that test paper strip 1 from rocking to make test paper strip 1 paste in order to heighten the chromatography effect on the lateral wall of first cavity 11. Preferably, the top of the rib 15 is provided with a guide slope 16 for guiding the test strip 1, so that the test strip 1 can be easily placed in a designated position of the first cavity 11 under the guiding action of the guide slope 16.

Further, a result observation area 17 is arranged on the side wall of the first cavity 11, and a highlight convex surface is arranged in the result observation area 17, so that the detection result can be read conveniently.

Furthermore, the first cavity 11 is provided with the air holes 18, and after the detection tube is inverted, the test strip 1 can be in the same pressure environment as the outside, so that the chromatographic detection effect can be effectively improved. The airing hole 18 of the present embodiment is provided on the bottom surface of the first cavity 11. In the production process, the defects that the product is perforated and the like due to the fact that the rubber punching and bending die insert is adopted can be avoided, and the requirement for die stripping can be met.

Further, a second cavity 19 for storing the liquid medicament is arranged in the tube body 10, and a second opening 20 is arranged on the top surface of the second cavity 19. Be equipped with the rib 21 of being convenient for elute the sample on the swab on the lateral wall of second cavity 19 of this embodiment, utilize the scraping effect of rib 21 to the swab, the sample on the elution swab of being convenient for improves sample elution rate.

Further, the second cavity 19 includes a lower cavity 19a located at the lower part and a transition section 19b located at the upper part, the second opening 20 is square, and the inner wall of the lower cavity 19a is cylindrical; the transition section 19b serves to smoothly transition between the second opening 20 and the lower cavity 19 a. The transition section is arranged to enable the second opening and the lower cavity to be in smooth transition, so that liquid can be prevented from being hung at the position of the second opening, and packaging is facilitated.

Further, the bottom of the second cavity 19 is provided with a closing section 22, the inner diameter of the closing section 22 is gradually reduced along the direction from top to bottom, and the bottom of the closing section 22 is provided with an injection molding wave point 23. The bottom of the second cavity is provided with the closing section, and the bottom of the closing section is provided with the injection molding wave point, so that the bottom of the second cavity can be thickened, and the glue can be fed into the mold in the production process.

Further, as shown in fig. 13, a cover groove 31 with an open bottom is formed in the tube cover 30 of the present embodiment, a notch of the cover groove 31 forms a cover opening 32, the tube cover 30 covers the upper end of the tube body 10, and a third cavity 33 for communicating the first cavity 11 and the second cavity 19 is formed between the tube cover 30 and the tube body 10.

As shown in fig. 12, the outer wall of the tube body 10 of the present embodiment is provided with a limiting rib 24 for limiting the tube cover 30, the limiting rib 24 divides the tube body into an upper tube body part 10a and a lower tube body part 10b, and the tube cover 30 covers the upper tube body part 10 a; the axial length of the upper portion 10a of the tube body is smaller than the depth of the cover groove 31, so that after the tube cover 30 is covered on the upper portion 10a of the tube body, under the limiting action of the limiting convex rib 24, a gap is formed between the bottom of the cover groove 31 and the top surface of the tube body 10, and a third cavity 33 is formed.

Further, a sealing structure is provided between the tube body 10 and the tube cap 30. the sealing structure of the present embodiment employs a sealing rib 37 provided between the tube cap 30 and the stopper rib 24. Specifically, the sealing rib 37 may be provided on the bottom surface of the tube cover 30, and the sealing rib may also be provided on the upper side surface of the position-restricting convex rib 24. The sealing rib 37 of the present embodiment may be provided on the bottom surface of the tube cover 30. In order to ensure that the tube body 10 and the tube cover 30 have enough combining force to ensure the sealing effect, the upper portion 10a of the tube body of the embodiment is provided with a reducing section 27 for interference fit with the tube cover 30 at a position close to the limiting convex rib 24; any two planes parallel to each other and perpendicular to the axis of the pipe body have similar figures between the cross sections taken on the reducer section 27, and the geometrical size of the cross section taken on the lower plane is larger than that taken on the upper plane, so that the coupling force between the cap 30 and the pipe body 10 can be ensured.

Further, a positioning structure is disposed between the tube 10 and the tube cover 30. The positioning structure of the present embodiment includes positioning protrusions 26 and positioning grooves 35 provided in one-to-one correspondence with the positioning protrusions 26. Specifically, the positioning structure may be that the positioning protrusion 26 is disposed on the outer wall of the upper portion 10a of the tube body, and the positioning groove 35 is disposed on the side wall of the cover groove 31; the positioning structure may also be such that the positioning groove 35 is provided on the outer wall of the tube body upper portion 10a and the positioning projection 26 is provided on the side wall of the cover groove 31. The positioning projection 26 of the present embodiment is provided on the outer wall of the upper portion 10a of the pipe body, and the positioning groove 35 is provided on the side wall of the cover groove 31.

Further, the bottom of the cover groove 31 is provided with a tube cover protrusion 36 protruding downwards to reduce the volume of the third cavity 33, so as to reduce the requirement for the usage amount of the liquid medicament.

The following describes in detail an embodiment of the method for packaging an integrated reaction detector according to the present invention with reference to the above-mentioned embodiment of the integrated reaction detector of the present embodiment.

The method for packaging the integrated reaction detection tube comprises the following steps:

1) after the liquid medicine is injected into the second cavity 19, a sealing film is attached to the second opening 20; then, the test strip 1 is placed in the first cavity 11, and the first end 4 of the test strip 1 extends out of the first opening;

2) the cap 30 is put on the tube 10.

Preferably, a desiccant is placed in the third cavity 33 before the tube cover 30 is placed over the tube 10 to keep the tube dry.

Preferably, after the test strip 1 is placed in the first cavity 11, a fixing plug 13 is mounted on the first opening 12. Play the effect of the first end of location test paper strip 1, invert the in-process at the test tube moreover, can effectively prevent that the liquid reagent that splashes from entering into first cavity 11, and then avoid the liquid reagent that splashes to pollute NC membrane 3 of test paper strip, can effectively improve the success rate of chromatography detection.

The following describes in detail a specific embodiment of the method of using the integrated reaction detector of the present invention with reference to the above-mentioned specific embodiment of the integrated reaction detector of the present example.

In the using method of the integrated reaction detection tube of this embodiment, specifically, in the detection tube of this embodiment, the test strip 1 is placed in the first cavity 11, the liquid medicament is placed in the second cavity 19, and the sealing film is attached to the second opening 20. Specifically, the application method of the integrated reaction detection tube of the embodiment includes the following steps:

the method comprises the following steps: the tube cover 30 is taken off from the tube body 10, and the sealing film on the second opening 20 is torn off; specifically, when the desiccant is placed in the third cavity 33, after the tube cover 30 is removed from the tube body 10, the desiccant is removed, and then the sealing film on the second opening 20 is torn off;

step two: extending the sampling swab into the second cavity 19, mixing the sample to be detected with the liquid medicament, breaking the sampling swab and leaving the broken sampling swab in the second cavity 19;

step three: covering the tube body 10 with the tube cover 30;

step four: the integrated reaction detection tube of the embodiment is inverted, so that the liquid medicament mixed with the sample to be detected contacts the first end 2 of the test strip 1 through the third cavity 33;

step five: the test result was observed by the test strip 1.

The embodiment also provides an application method of the integrated reaction detection tube, and the integrated reaction detection tube can be applied to immunochromatography detection of novel coronavirus, influenza a, influenza b, respiratory syncytial virus or rotavirus adenovirus.

The above-mentioned embodiments are merely preferred embodiments for fully illustrating the present invention, and the scope of the present invention is not limited thereto. The equivalent substitutions or changes made by the person skilled in the art on the basis of the present invention are all within the protection scope of the present invention. The protection scope of the utility model is subject to the claims.

Claims (17)

1. The utility model provides an integrated form reaction detection tube, includes body and tube cap, its characterized in that: the internal first cavity that is used for placing the test paper strip that is equipped with of body, the top surface of first cavity is equipped with and is used for the first opening that the test paper strip passes through, just install the fixed stopper on the first opening, be equipped with the groove of stepping down that matches with the first end of test paper strip on the fixed stopper.

2. The integrated reaction detection tube of claim 1, wherein: and a rib for positioning the second end of the test strip is arranged on the side wall of the first cavity.

3. The integrated reaction detection tube of claim 1, wherein: and a result observation area is arranged on the side wall of the first cavity, and a highlight convex surface is arranged in the result observation area.

4. The integrated reaction detection tube of claim 1, wherein: and air holes are formed in the first cavity.

5. The integrated reaction detection tube of claim 4, wherein: the air holes are formed in the bottom surface of the first cavity.

6. The integrated reaction detection tube according to any one of claims 1 to 5, wherein: the second cavity for storing liquid medicament is arranged in the tube body, and a second opening is formed in the top surface of the second cavity.

7. The integrated reaction detection tube of claim 6, wherein: the side wall of the second cavity is provided with a rib which is convenient for eluting the sample on the swab.

8. The integrated reaction detection tube of claim 6, wherein: the bottom of second cavity is equipped with the closing-in section, the internal diameter of closing-in section reduces along the orientation from last to down gradually, just the bottom of closing-in section is equipped with the ripples point of moulding plastics.

9. The integrated reaction detection tube of claim 6, wherein: the second cavity comprises a lower cavity positioned at the lower part and a transition section positioned at the upper part, the second opening is square, and the inner wall of the lower cavity is cylindrical; the transition section is used for enabling the second opening and the lower cavity to be smoothly connected.

10. The integrated reaction detection tube of claim 6, wherein: be equipped with bottom surface open-ended lid groove in the tube cap, the notch in lid groove forms the flap, the tube cap lid the upper end of body and tube cap with form between the body and be used for the intercommunication the third cavity of first cavity and second cavity.

11. The integrated reaction detection tube of claim 10, wherein: the outer wall of the pipe body is provided with a limiting convex rib for limiting the pipe cover, the limiting convex rib divides the pipe body into an upper part and a lower part, and the pipe cover covers the upper part of the pipe body; the axial length of the upper part of the pipe body is smaller than the depth of the cover groove.

12. The integrated reaction detection tube of claim 11, wherein: a sealing structure is arranged between the pipe body and the pipe cover; the sealing structure adopts a sealing rib arranged between the pipe cover and the limiting convex rib; the sealing rib is arranged on the bottom surface of the pipe cover, or the sealing rib is arranged on the upper side surface of the limiting convex rib.

13. The integrated reaction detection tube of claim 12, wherein: a reducer section which is in interference fit with the pipe cover is arranged at the position, close to the limiting convex rib, of the upper part of the pipe body; the figures of the sections of any two planes which are parallel to each other and vertical to the axis of the pipe body and cut on the reducer section are similar, and the geometrical size of the section cut by the lower plane is larger than that of the section cut by the upper plane.

14. The integrated reaction detection tube of claim 10, wherein: a sealing structure is arranged between the pipe body and the pipe cover; the sealing structure comprises a sealing convex rib and a sealing groove which are matched with each other; the sealing convex rib is arranged on the outer wall of the upper part of the pipe body, and the sealing groove is arranged on the side wall of the cover groove; or the sealing groove is arranged on the outer wall of the upper part of the pipe body, and the sealing convex rib is arranged on the side wall of the cover groove.

15. The integrated reaction detection tube according to claim 10, wherein: a positioning structure is arranged between the pipe body and the pipe cover; the positioning structure comprises positioning bulges and positioning grooves which are arranged in one-to-one correspondence with the positioning bulges; the positioning protrusion is arranged on the outer wall of the upper part of the pipe body, and the positioning groove is arranged on the side wall of the cover groove; or the positioning groove is arranged on the outer wall of the upper part of the pipe body, and the positioning bulge is arranged on the side wall of the cover groove.

16. The integrated reaction detection tube of claim 15, wherein: a sealing structure is arranged between the pipe body and the pipe cover, and comprises a sealing convex rib and a sealing groove which are matched with each other;

the side wall of the cover groove comprises an upper side wall section and a lower side wall section, the upper side wall section is located at the upper part, the lower side wall section is located at the lower part, the geometric dimension of the lower side wall section is larger than that of the upper side wall section, the positioning protrusion or the positioning groove is arranged on the lower side wall section, and the sealing convex rib or the sealing groove is arranged on the upper side wall section.

17. The integrated reaction detection tube of claim 10, wherein: and a pipe cover bulge which is downwards bulged to reduce the volume of the third cavity is arranged at the bottom of the cover groove.

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