CN216900093U - Probe board for cell detection - Google Patents
Probe board for cell detection Download PDFInfo
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- CN216900093U CN216900093U CN202122649625.9U CN202122649625U CN216900093U CN 216900093 U CN216900093 U CN 216900093U CN 202122649625 U CN202122649625 U CN 202122649625U CN 216900093 U CN216900093 U CN 216900093U
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- cell detection
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- step groove
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Abstract
The utility model discloses a probe plate for cell detection, wherein probe bodies are arranged in a strip shape, the sides of the probe bodies are fixed to form a probe group, the probe bodies corresponding to the two ends of the probe group are provided with connecting lugs, a step groove for accommodating and placing the connecting lugs is formed in a frame, a clamping strip for clamping the connecting lugs is installed in the step groove, one end of the clamping strip is hinged with the corresponding side of the frame in a turnover mode, and the other end of the clamping strip is connected with the frame in a clamping mode. The card strip is fixed and fixed with the engaging lug compaction through the buckle, and the probe group is difficult not hard up, also need not worry cell sampling hole's conflict effect and bounce-back, and the frame of this device can used repeatedly, and different test sample only need change probe group, practices thrift the cost.
Description
Technical Field
The utility model belongs to the technical field of cell detection equipment, and particularly relates to a probe plate for cell detection.
Background
An extracellular flow meter is the most advanced device for measuring cell energy metabolism. The instrument is designed by a special probe plate and a cell culture micro-porous plate, is controlled by a preset program within a specific time, adds up to four medicaments from the probe plate to a culture medium in a cell plate to be detected, and synchronously detects dissolved oxygen variation (OCR) and pH value variation (ECAR) in real time by utilizing a non-invasive patent optical sensor in a microenvironment of about 2.2-5.6ul temporarily formed during measurement, so that the energy metabolism state of two large energy conversion paths (aerobic metabolism and glycolysis of mitochondria) in cells is quickly known. The method has rapid and accurate test on metabolic indexes such as cell basal metabolic rate, ATP conversion, membrane integrity, limiting respiration rate, mitochondrial function, oxygen free radical generation and the like, saves time and labor, and has scientific and convincing experimental data.
The XF96 model instrument is the one with the largest detection flux at present, and comprises a 96-hole cell culture micro-porous plate and a probe plate which are both made of polystyrene materials. The cell culture micro-plate is used for culturing cells, the influence of drugs on cell metabolism needs to be proved after drug tests or other tests on the cells, and a culture solution containing the cells is added when the micro-plate is used. And probe card and micropore board cooperation are used, and mutual block from top to bottom, probe card include the frame, and the embedded optical fiber post that has of frame, optical fiber post and cell culture hole one-to-one, the avris of optical fiber post has the ware of beating, and the ware of beating is four evenly distributed in the optical fiber post, and its bottom has the hole, adds inhibitor, coupling agent and irritant etc. according to the demand during the use, tests the influence that produces the cell culture. The fiber column is hollow designed for fiber insertion and the bottom seal is used for probe application and contact with the cell fluid. And after the detection, putting the micro-porous plate and the probe plate which are covered together into a data analyzer for detection.
The probe plate of extracellular flow instrument uses to the micropore board cooperation, and the lid closes on the micropore board during use, and the quantity of probe corresponds microporous quantity, and is present mostly 96 hole equipment, and its probe plate quantity that corresponds also is 96, and current probe plate probe is fixed knot with the frame for guarantee the probe enough stability when inserting the application of sample hole, prevent to drop. However, not all cell tests use 96-well, and the laboratory has no extra small-sized products, but only uses 96-well, and the extra probes are wasted. Therefore, the utility model mainly solves the problem of waste caused by adopting a probe with a porous specification in the process of detecting a small amount of samples.
SUMMERY OF THE UTILITY MODEL
The utility model aims to provide a probe plate for cell detection, which mainly solves the problem of waste caused by using a probe with a porous specification in a process of detecting a small amount of samples.
In order to solve the technical problems, the utility model is realized by the following technical scheme:
a probe plate for cell detection comprises a frame, wherein probe bodies arranged in a dot matrix manner are arranged in the frame, and each probe body comprises an optical fiber column and a pesticide spraying hole positioned on the side of the optical fiber column;
the probe bodies are arranged in a strip shape, the sides of the probe bodies are fixed to form probe sets, and the probe sets can be detachably mounted on the frame;
the probe body that the probe group both ends correspond has the engaging lug, the frame is seted up and is held and place the step groove of engaging lug, the card strip of block engaging lug is installed in the step groove, the one end of card strip is articulated with the frame avris that corresponds is convertible, and the other end and the frame buckle of card strip are connected.
Further, the bottom of the step groove is provided with a silica gel pad.
Furthermore, the connecting lug is provided with a positioning hole, and the position of the silica gel pad corresponding to the positioning hole is provided with a limiting bulge.
Furthermore, the inner bending part of the frame is provided with a reinforcing rib.
Further, the corner positions of the frame are provided with raised stripes.
The utility model has the following beneficial effects:
according to test object's quantity installation probe group, the installation is arranged in proper order to the other end extension by the hinged end of card strip to the probe group, and the probe group is adjacent inseparable, and the engaging lug of probe group tip is installed in the step groove, then the card strip at pressfitting both ends, and the card strip is fixed and will the engaging lug compaction is fixed through the buckle, and the probe group is difficult not hard up, also need not worry the conflict effect in cell application of sample hole and bounce-back, and the frame of this device can used repeatedly, and different test samples only need change the probe group, practices thrift the cost.
Of course, it is not necessary for any product to practice the utility model to achieve all of the above-described advantages at the same time.
Drawings
In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings used in the description of the embodiments will be briefly introduced below, and it is obvious that the drawings in the following description are only some embodiments of the present invention, and it is obvious for those skilled in the art that other drawings can be obtained according to the drawings without creative efforts.
FIG. 1: the top structure of the frame of the utility model.
FIG. 2: the structure of the probe set of the utility model.
FIG. 3: the utility model relates to a structure diagram of the bottom of a frame.
In the drawings, the components represented by the respective reference numerals are listed below:
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
In the description of the present invention, it is to be understood that the terms "opening," "upper," "lower," "thickness," "top," "middle," "length," "inner," "peripheral," and the like are used in an orientation or positional relationship that is merely for convenience in describing and simplifying the description, and do not indicate or imply that the referenced component or element must have a particular orientation, be constructed and operated in a particular orientation, and thus should not be considered as limiting the present invention.
As shown in fig. 1-3: a probe plate for cell detection comprises a frame 1, wherein a probe body 21 which is arranged in a dot matrix manner is arranged in the frame 1, and comprises an optical fiber column and a pesticide spraying hole which is positioned at the side of the optical fiber column; the method is characterized in that:
the probe bodies 21 are arranged in a strip shape, the sides of the probe bodies are fixed to form probe groups 2, and the probe groups 2 can be detachably mounted on the frame 1; typically corresponding to a 96 well probe card, 8 in a set to form a strip.
According to the utility model, the number of the probe sets is installed according to the number of the test objects, the probe sets extend from the hinged ends of the clamping strips to the other ends of the clamping strips and are sequentially arranged and installed, the probe sets are adjacent and compact, the connecting lugs at the end parts of the probe sets are installed in the stepped grooves, then the clamping strips at the two ends are pressed, the clamping strips are fixed through the buckles and press-fix the connecting lugs, the probe sets are not easy to loosen, and the rebounding is not caused by the interference effect of the cell sample adding holes.
The frame of the device can be reused, and different test samples only need to be replaced by probe sets, so that the cost is saved.
As shown in fig. 1: the bottom of the step groove 11 is provided with a silica gel pad 4. The tightness between the connecting lug and the clamping strip is improved.
As shown in fig. 1-2: the connecting lug 22 is provided with a positioning hole 23, and the position of the silica gel pad 4 corresponding to the positioning hole 23 is provided with a limiting bulge 41. During installation, the locating hole corresponds spacing protruding installation for the probe group is installed in the location, and the probe body of being convenient for pinpoints cell application of sample hole.
As shown in fig. 3: the inner bending part of the frame 1 is provided with a reinforcing rib 12. The frame is polystyrene material for improve the intensity of frame.
As shown in fig. 1: the corner positions of the frame 1 have raised stripes 13. The position of holding between the fingers is held to the stripe correspondence for improve frictional force, it is more stable to be convenient for to hand.
In the description herein, references to the description of "one embodiment," "an example," "a specific example" or the like are intended to mean that a particular feature, structure, material, or characteristic described in connection with the embodiment or example is included in at least one embodiment or example of the utility model. In this specification, the schematic representations of the terms used above do not necessarily refer to the same embodiment or example. Furthermore, the particular features, structures, materials, or characteristics described may be combined in any suitable manner in any one or more embodiments or examples.
The preferred embodiments of the utility model disclosed above are intended to be illustrative only. The preferred embodiments are not intended to be exhaustive or to limit the utility model to the precise forms disclosed. Obviously, many modifications and variations are possible in light of the above teaching. The embodiments were chosen and described in order to best explain the principles of the utility model and the practical application, to thereby enable others skilled in the art to best utilize the utility model. The utility model is limited only by the claims and their full scope and equivalents.
Claims (5)
1. A probe plate for cell detection comprises a frame (1), wherein probe bodies (21) which are arranged in a dot matrix manner are arranged in the frame (1), and each probe body comprises an optical fiber column and a pesticide spraying hole which is positioned at the side of the optical fiber column; the method is characterized in that:
the probe bodies (21) are arranged in a strip shape, the sides of the probe bodies are fixed to form probe sets (2), and the probe sets (2) can be detachably mounted on the frame (1);
probe body (21) that probe group (2) both ends correspond have engaging lug (22), step groove (11) of holding and placing engaging lug (22) are seted up in frame (1), block strip (3) of block engaging lug (22) are installed in step groove (11), the one end of block strip (3) is connected with frame (1) avris that corresponds is convertible articulated, and the other end and frame (1) buckle of block strip (3) are connected.
2. The probe card for cell detection according to claim 1, wherein: the bottom of the step groove (11) is provided with a silica gel pad (4).
3. The probe card for cell detection according to claim 2, wherein: the connecting lug (22) is provided with a positioning hole (23), and the position of the silica gel pad (4) corresponding to the positioning hole (23) is provided with a limiting bulge (41).
4. The probe card for cell detection according to claim 1, wherein: the inner bending part of the frame (1) is provided with a reinforcing rib (12).
5. The probe card for cell detection according to claim 1, wherein: the corner position of the frame (1) is provided with a raised stripe (13).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202122649625.9U CN216900093U (en) | 2021-10-29 | 2021-10-29 | Probe board for cell detection |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202122649625.9U CN216900093U (en) | 2021-10-29 | 2021-10-29 | Probe board for cell detection |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN216900093U true CN216900093U (en) | 2022-07-05 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202122649625.9U Active CN216900093U (en) | 2021-10-29 | 2021-10-29 | Probe board for cell detection |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN216900093U (en) |
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2021
- 2021-10-29 CN CN202122649625.9U patent/CN216900093U/en active Active
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