CN219728972U - Kit for uridine detection - Google Patents
Kit for uridine detection Download PDFInfo
- Publication number
- CN219728972U CN219728972U CN202321146134.5U CN202321146134U CN219728972U CN 219728972 U CN219728972 U CN 219728972U CN 202321146134 U CN202321146134 U CN 202321146134U CN 219728972 U CN219728972 U CN 219728972U
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- CN
- China
- Prior art keywords
- kit
- box
- uridine
- protection box
- wall
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- DRTQHJPVMGBUCF-XVFCMESISA-N Uridine Chemical compound O[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1N1C(=O)NC(=O)C=C1 DRTQHJPVMGBUCF-XVFCMESISA-N 0.000 title claims abstract description 30
- 238000001514 detection method Methods 0.000 title claims abstract description 29
- DRTQHJPVMGBUCF-PSQAKQOGSA-N beta-L-uridine Natural products O[C@H]1[C@@H](O)[C@H](CO)O[C@@H]1N1C(=O)NC(=O)C=C1 DRTQHJPVMGBUCF-PSQAKQOGSA-N 0.000 title claims abstract description 15
- DRTQHJPVMGBUCF-UHFFFAOYSA-N uracil arabinoside Natural products OC1C(O)C(CO)OC1N1C(=O)NC(=O)C=C1 DRTQHJPVMGBUCF-UHFFFAOYSA-N 0.000 title claims abstract description 15
- 229940045145 uridine Drugs 0.000 title claims abstract description 15
- 238000002955 isolation Methods 0.000 claims abstract description 31
- 230000000087 stabilizing effect Effects 0.000 claims abstract description 8
- 238000007789 sealing Methods 0.000 claims abstract description 6
- 230000007246 mechanism Effects 0.000 claims abstract description 5
- 239000006260 foam Substances 0.000 claims description 10
- 239000003153 chemical reaction reagent Substances 0.000 claims description 7
- 230000009286 beneficial effect Effects 0.000 abstract description 5
- DJJCXFVJDGTHFX-UHFFFAOYSA-N Uridinemonophosphate Natural products OC1C(O)C(COP(O)(O)=O)OC1N1C(=O)NC(=O)C=C1 DJJCXFVJDGTHFX-UHFFFAOYSA-N 0.000 description 11
- FOGRQMPFHUHIGU-UHFFFAOYSA-N Uridylic acid Natural products OC1C(OP(O)(O)=O)C(CO)OC1N1C(=O)NC(=O)C=C1 FOGRQMPFHUHIGU-UHFFFAOYSA-N 0.000 description 11
- DJJCXFVJDGTHFX-XVFCMESISA-N uridine 5'-monophosphate Chemical compound O[C@@H]1[C@H](O)[C@@H](COP(O)(O)=O)O[C@H]1N1C(=O)NC(=O)C=C1 DJJCXFVJDGTHFX-XVFCMESISA-N 0.000 description 11
- 210000002700 urine Anatomy 0.000 description 6
- 230000000694 effects Effects 0.000 description 5
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 description 4
- 238000005299 abrasion Methods 0.000 description 3
- 241000252254 Catostomidae Species 0.000 description 2
- 108090000790 Enzymes Proteins 0.000 description 2
- 102000004190 Enzymes Human genes 0.000 description 2
- 239000007853 buffer solution Substances 0.000 description 2
- 238000005259 measurement Methods 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 108010092364 Glucuronosyltransferase Proteins 0.000 description 1
- 108090000992 Transferases Proteins 0.000 description 1
- HDYANYHVCAPMJV-LXQIFKJMSA-N UDP-alpha-D-glucuronic acid Chemical compound C([C@@H]1[C@H]([C@H]([C@@H](O1)N1C(NC(=O)C=C1)=O)O)O)OP(O)(=O)OP(O)(=O)O[C@H]1O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]1O HDYANYHVCAPMJV-LXQIFKJMSA-N 0.000 description 1
- XCCTYIAWTASOJW-XVFCMESISA-N Uridine-5'-Diphosphate Chemical compound O[C@@H]1[C@H](O)[C@@H](COP(O)(=O)OP(O)(O)=O)O[C@H]1N1C(=O)NC(=O)C=C1 XCCTYIAWTASOJW-XVFCMESISA-N 0.000 description 1
- 239000012445 acidic reagent Substances 0.000 description 1
- 230000004075 alteration Effects 0.000 description 1
- 238000003759 clinical diagnosis Methods 0.000 description 1
- 239000003086 colorant Substances 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000002207 metabolite Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000035790 physiological processes and functions Effects 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 238000005070 sampling Methods 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
Landscapes
- Investigating Or Analysing Biological Materials (AREA)
Abstract
The utility model discloses a kit for uridine detection, which relates to the technical field of detection kits and comprises a protection box and a reference component, wherein one side of the top end of the protection box is hinged with a sealing cover through a hinge, the inside of the protection box is provided with a detection component, the detection component comprises two connecting grooves, two connecting blocks, a first isolation box, a supporting plate and a stabilizing mechanism, the two connecting grooves are formed in one side corresponding to the protection box, and the inside of the two connecting grooves are both connected with the connecting blocks in a sliding manner, and the kit has the beneficial effects that: the arc limiting plate that sets up through spacing spring at the inner wall of standing groove is used for spacing the pipe wall of sample cell, and applicable specification is more sample cell, all is provided with the rubber circle on the top of every standing groove for the pipe wall of protection sample cell reduces collision and wearing and tearing, when the sample cell in the first isolation box takes place unexpected pollution, the pull rod of accessible pulling both sides, the pull rod pulls out first isolation box from between two spread grooves.
Description
Technical Field
The utility model relates to a kit, in particular to a kit for detecting uridine, and belongs to the technical field of detection kits.
Background
Uridylic acid is one of the important metabolites in the human body, and changes in its levels may be associated with various diseases or physiological states. The kit provides a simple and rapid biochemical index by detecting the level of the uridylic acid in urine, is beneficial to medical research and clinical diagnosis, and is needed for measuring the level of the uridylic acid in urine;
the uridine diphosphate glucuronic acid transferase gene polymorphism detection kit disclosed in the application number of CN201220164654.4 has the beneficial effects that the kit has a simple structure, reasonable design, convenient use, easy manufacture and difficult pollution in the detection process; the kit has the advantages of high accuracy, short time consumption and the like when detecting the polymorphism of the uridine diphosphate glucuronyltransferase gene, but the detection kit has the following defects:
in actual use, because market detection sample cell specification variety is more, this detection kit does not carry out the effect promotion in the aspect of to the suitability of storing many specifications sample cell, and application scope is lower, when unexpected emergence pollution in sample district, inconvenient to dismantle alone the sample district, uses comparatively inconvenient in the aspect of colour chip contrast and time record simultaneously.
Disclosure of Invention
The utility model aims to provide a kit for detecting uridine, which is used for solving the problems that the detection kit is not beneficial to improving the applicability of storing multiple-specification sample tubes, has a low application range, is inconvenient to detach a sample area independently when the sample area is polluted accidentally, and is inconvenient to use in color card comparison and time recording.
In order to achieve the above purpose, the present utility model provides the following technical solutions: the utility model provides a kit that uridine detected, includes protection box and reference subassembly, one side on the top of protection box has sealed lid through the hinge, the inside of protection box is equipped with detection component, detection component includes two spread grooves, two connecting blocks, first isolation box, backup pad and stabilizing mean, two the spread groove is seted up in the corresponding one side of protection box, two the equal sliding connection in inside of spread groove has the connecting block, two fixed first isolation box that is equipped with between the connecting block, the fixed backup pad that is equipped with in top of first isolation box inner wall, the opposite side of protection box inner wall is fixed and is provided with two symmetrical second isolation boxes.
Preferably, the stabilizing mean includes a plurality of standing groove, a plurality of spacing spring and a plurality of arc limiting plate, and a plurality of the standing groove equidistance is offered on the surface of backup pad, every one side of standing groove inner wall is all through spacing spring elastic connection having arc limiting plate.
Preferably, each of the top ends of the placing grooves is fixedly provided with a rubber ring, the top ends of the first isolation boxes are fixedly provided with four fixed blocks which are equidistantly arranged, and lifting rods are respectively and rotatably connected between every two corresponding fixed blocks.
Preferably, the reference assembly comprises a foam plate, a mounting groove, a contrast card and a timer main body, wherein the foam plate is fixedly arranged at the bottom end of the sealing cover, the mounting groove is formed in the middle of the foam plate, the contrast card is fixedly arranged in the mounting groove, and the timer main body is fixedly arranged on the surface of the protection box.
Preferably, the inner wall of one of the second isolation boxes is fixedly provided with a first placing plate, and the surface of the first placing plate is provided with three reagent bottles which are arranged at equal intervals.
Preferably, the inner wall of the second isolation box is fixedly provided with a second placing plate, and the surface of the second placing plate is provided with a plurality of sampling device suction heads which are equidistantly arranged.
Preferably, the four corners of protection box bottom all are fixed and are equipped with the supporting legs.
Compared with the related art, the kit for detecting uridine provided by the utility model has the following components in percentage by weight
The beneficial effects are that:
1. the second placing plate is used for storing a plurality of sample injector suction heads, for detecting sample tubes of different specifications in the applicable market, the arc-shaped limiting plates arranged on the inner walls of the placing grooves through the limiting springs are used for limiting the tube walls of the sample tubes, and can be applicable to sample tubes of more specifications, rubber rings are arranged at the top ends of the placing grooves and used for protecting the tube walls of the sample tubes to reduce collision and abrasion, so that a better protection effect is achieved;
2. for improving the efficiency of measuring work, be provided with the contrast card in the inside of mounting groove and be used for reading measuring result, contain different colour pieces, correspond different uridylic acid concentration ranges, the time-recorder main part on protection box surface is convenient for record detection time.
Drawings
FIG. 1 is a schematic diagram of the structure of the present utility model;
FIG. 2 is a schematic top view of the present utility model;
FIG. 3 is a schematic side view of the present utility model;
fig. 4 is an enlarged schematic view of the structure of fig. 2 at a.
In the figure: 1. a protective case; 2. sealing cover; 3. a detection assembly; 4. a second isolation box; 5. a reference assembly; 6. a fixed block; 7. a lifting rod; 8. a first placing plate; 9. a reagent bottle; 10. a second placing plate; 11. a sample applicator tip; 12. supporting feet; 31. a connecting groove; 32. a connecting block; 33. a first isolation box; 34. a support plate; 35. a stabilizing mechanism; 351. a placement groove; 352. a limit spring; 353. an arc limiting plate; 354. a rubber ring; 51. a foam board; 52. a mounting groove; 53. a contrast card; 54. a timer body.
Detailed Description
The following description of the embodiments of the present utility model will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present utility model, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the utility model without making any inventive effort, are intended to be within the scope of the utility model.
Example 1:
referring to fig. 1-4, the utility model provides a kit for detecting uridine, which comprises a protection box 1 and a reference component 5, wherein one side of the top end of the protection box 1 is hinged with a sealing cover 2 through a hinge, the inside of the protection box 1 is provided with a detection component 3, the detection component 3 comprises two connecting grooves 31, two connecting blocks 32, a first isolation box 33, a supporting plate 34 and a stabilizing mechanism 35, the two connecting grooves 31 are arranged on one corresponding side of the protection box 1, the inside of the two connecting grooves 31 are both connected with the connecting blocks 32 in a sliding manner, the first isolation box 33 is fixedly arranged between the two connecting blocks 32, the top of the inner wall of the first isolation box 33 is fixedly provided with a supporting plate 34, and the other side of the inner wall of the protection box 1 is fixedly provided with two symmetrical second isolation boxes 4;
the stabilizing mechanism 35 comprises a plurality of placing grooves 351, a plurality of limiting springs 352 and a plurality of arc-shaped limiting plates 353, wherein the placing grooves 351 are equidistantly formed on the surface of the supporting plate 34, and one side of the inner wall of each placing groove 351 is elastically connected with each arc-shaped limiting plate 353 through the limiting spring 352;
the top end of each placing groove 351 is fixedly provided with a rubber ring 354, the top end of the first isolation box 33 is fixedly provided with four fixed blocks 6 which are equidistantly arranged, and a lifting rod 7 is rotatably connected between every two corresponding fixed blocks 6;
the inner wall of one second isolation box 4 is fixedly provided with a first placing plate 8, and the surface of the first placing plate 8 is clamped with three reagent bottles 9 which are equidistantly arranged;
the inner wall of the other second isolation box 4 is fixedly provided with a second placing plate 10, and the surface of the second placing plate 10 is provided with a plurality of sample injector suckers 11 which are equidistantly arranged;
the four corners of the bottom end of the protection box 1 are fixedly provided with supporting feet 12;
specifically, as shown in fig. 1, fig. 2, fig. 3 and fig. 4, a uridylic acid reagent for measuring the uridylic acid level in urine comprises a uridylic acid enzyme, hydrogen peroxide, buffer solution and three reagent bottles 9 on the surface of a first placing plate 8, a second placing plate 10 is used for storing a plurality of sample injector suction heads 11, for detecting sample tubes with different specifications in the market, an arc limiting plate 353 arranged on the inner wall of a placing groove 351 through a limiting spring 352 is used for limiting the tube wall of the sample tube, the sample tubes with more specifications are applicable, rubber rings 354 are arranged on the top end of each placing groove 351 and used for protecting the tube wall of the sample tube to reduce collision and abrasion, so that a better protection effect is achieved, when the sample tubes in the first isolating box 33 are accidentally polluted, the first isolating box 33 is conveniently detached by pulling two lifting rods 7, the first isolating box 33 is pulled out from between two connecting grooves 31 by the lifting rods 7, other objects of the first isolating box 33 are independently detached to prevent the pollution of the protecting box 1, and the other objects of the protecting box 1 are better isolated, and the subsequent workers are convenient to process.
Example 2:
the reference component 5 comprises a foam plate 51, a mounting groove 52, a contrast card 53 and a timer main body 54, wherein the foam plate 51 is fixedly arranged at the bottom end of the sealing cover 2, the mounting groove 52 is formed in the middle of the foam plate 51, the contrast card 53 is fixedly arranged in the mounting groove 52, and the timer main body 54 is fixedly arranged on the surface of the protection box 1;
specifically, as shown in fig. 1, 2 and 3, first, in order to improve the efficiency of the measurement work, a contrast card 53 is provided inside the mounting groove 52 for reading the measurement result, and the timer main body 54 on the surface of the protection box 1 is convenient for recording the detection time, including different color blocks, corresponding to different uridylic acid concentration ranges.
Working principle: when the kit is particularly used, the kit is firstly used for measuring the uridylic acid level of urine, comprises uridylic acid enzyme, hydrogen peroxide, buffer solution and the like which can be stored through three reagent bottles 9 on the surface of a first placing plate 8, a second placing plate 10 is used for storing a plurality of sample injector suckers 11, for detecting sample tubes with different specifications in the market, an arc-shaped limiting plate 353 arranged on the inner wall of a placing groove 351 through a limiting spring 352 is used for limiting the tube wall of the sample tube, and can be suitable for sample tubes with more specifications, a rubber ring 354 is arranged at the top end of each placing groove 351 and used for protecting the tube wall of the sample tube to reduce collision and abrasion, so that a better protection effect is achieved, when the sample tube in a first isolation box 33 is accidentally polluted, for the convenience of dismantling the first isolation box 33, the lifting rod 7 on two sides is pulled, the lifting rod 7 pulls the first isolation box 33 out from between the two connecting grooves 31, the first isolation box 33 is independently dismantled to prevent other objects of the pollution prevention protection box 1, a good isolation effect is achieved, the subsequent treatment of workers is facilitated, urine samples are obtained, the urine samples are placed in clean sample tubes, a certain amount of uridylase reagent is added into the sample tubes through the sample injector suction head 11, the sample tubes are fully mixed, the reacted sample tubes are closely attached to the comparison card 53 to read color blocks with the closest colors in the test tubes on the color comparison card, the corresponding uridylic acid concentration ranges are recorded, the timer main body 54 on the surface of the protection box 1 is convenient for recording detection time, the use is more convenient, and the working efficiency is improved.
Although embodiments of the present utility model have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made therein without departing from the principles and spirit of the utility model, the scope of which is defined in the appended claims and their equivalents.
Claims (7)
1. The utility model provides a kit that uridine detected, includes protection box (1) and reference subassembly (5), its characterized in that, one side on the top of protection box (1) articulates through the hinge has sealed lid (2), the inside of protection box (1) is equipped with detection component (3), detection component (3) include two spread grooves (31), two connecting blocks (32), first isolation box (33), backup pad (34) and stabilizing mean (35), two the corresponding one side at protection box (1) is seted up in spread grooves (31), two equal sliding connection in inside of spread grooves (31) has connecting block (32), two fixed first isolation box (33) that are equipped with between connecting block (32), the fixed backup pad (34) that is equipped with in top of first isolation box (33) inner wall, the opposite side of protection box (1) inner wall is fixed and is provided with two symmetrical second isolation box (4).
2. A kit for uridine detection according to claim 1, wherein: the stabilizing mechanism (35) comprises a plurality of placing grooves (351), a plurality of limiting springs (352) and a plurality of arc limiting plates (353), wherein the placing grooves (351) are equidistantly formed in the surface of the supporting plate (34), and one side of the inner wall of each placing groove (351) is elastically connected with each arc limiting plate (353) through the limiting springs (352).
3. A kit for uridine detection according to claim 2, wherein: every the top of standing groove (351) is all fixed and is equipped with rubber circle (354), the fixed block (6) that are equipped with four equidistance settings in top of first isolation box (33), every two corresponding all rotate between fixed block (6) and be connected with lifter (7).
4. A kit for uridine detection according to claim 1, wherein: the reference assembly (5) comprises a foam plate (51), a mounting groove (52), a comparison card (53) and a timer main body (54), wherein the foam plate (51) is fixedly arranged at the bottom end of the sealing cover (2), the mounting groove (52) is formed in the middle of the foam plate (51), the comparison card (53) is fixedly arranged in the mounting groove (52), and the timer main body (54) is fixedly arranged on the surface of the protection box (1).
5. A kit for uridine detection according to claim 1, wherein: one of them the inner wall of second isolation box (4) is fixed to be equipped with first board (8) of placing, the surface card of board (8) is equipped with reagent bottle (9) that three equidistance set up is placed to the first.
6. A kit for uridine detection according to claim 1, wherein: the other inner wall of the second isolation box (4) is fixedly provided with a second placing plate (10), and the surface of the second placing plate (10) is provided with a plurality of sample injector suction heads (11) which are equidistantly arranged.
7. A kit for uridine detection according to claim 1, wherein: four corners of the bottom end of the protection box (1) are fixedly provided with supporting feet (12).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202321146134.5U CN219728972U (en) | 2023-05-12 | 2023-05-12 | Kit for uridine detection |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202321146134.5U CN219728972U (en) | 2023-05-12 | 2023-05-12 | Kit for uridine detection |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN219728972U true CN219728972U (en) | 2023-09-22 |
Family
ID=88031060
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202321146134.5U Active CN219728972U (en) | 2023-05-12 | 2023-05-12 | Kit for uridine detection |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN219728972U (en) |
-
2023
- 2023-05-12 CN CN202321146134.5U patent/CN219728972U/en active Active
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