CN216826241U

CN216826241U - Detection kit based on flow cytometry

Info

Publication number: CN216826241U
Application number: CN202122247776.1U
Authority: CN
Inventors: 徐松
Original assignee: Gaojing Shanghai Biotechnology Co ltd
Current assignee: Gaojing Shanghai Biotechnology Co ltd
Priority date: 2021-09-16
Filing date: 2021-09-16
Publication date: 2022-06-28
Anticipated expiration: 2031-09-16

Abstract

The utility model discloses a detect reagent box based on flow cytometry relates to kit technical field. The utility model comprises a rectangular box body, the top of which is connected with a supporting plate, the end part of which is connected with a box outer cover in a matching way; the supporting plate comprises a rectangular plate body, a plurality of through holes are formed in the rectangular plate body, and tubular surrounding edges are arranged on the upper surface of the rectangular plate body, which is positioned on the periphery of any through hole; a first magnetic ring is fixed on the upper surface of the rectangular plate body positioned on the peripheral side of the tubular surrounding edge, and one surface of the first fixed magnetic ring is connected with a second magnetic ring through a tubular film; during the use, run through the through hole with the test tube, and the tip cooperation of test tube is provided with the shading lid. The utility model realizes the shading of the test tube in the experimental process by arranging the first magnetic ring, the tubular membrane and the second magnetic ring in the supporting plate and matching with the shading cover, and the device has simple structure and convenient use; and can fix and shade test tubes of various different lengths and diameters.

Description

Detection kit based on flow cytometry

Technical Field

The utility model belongs to the technical field of the kit, especially, relate to a detect reagent box based on flow cytometry.

Background

The kit is a box for containing chemical reagents for detecting chemical components, drug residues, virus types and the like, and is generally applied to hospitals or pharmaceutical enterprises, and the production of the kit enables experimenters to get rid of heavy reagent preparation and optimization processes. The detection of various indexes is generally related to the fields of chemical industry, medicine, food biology, medical clinic and the like, and corresponding reagents are integrated in a reagent kit.

Flow Cytometry (FCM) is a new technology for quantitative analysis and sorting of chemical components on the surface or inside of individual cells. FCM separates cells of different cell sizes and intracellular granulometry mainly by collecting forward scattered light (FSC) and side scattered light (SSC), and enables detection of DNA, RNA, cytokines, cell surface antigens, etc. by recognizing cell surface and intracellular specific fluorescent markers. As a rapid cell analysis technology, the technology is not only applied to basic medical researches such as immunology, microbiology and the like, but also widely applied to clinical detection such as oncology, hematology and the like.

In the flow cytometry detection pretreatment process, a test tube filled with a sample needs to be stored and reacted in a dark place, and the test tube is placed in a light-tight drawer or a box with a larger size in the prior art, so that the light-tight effect can be achieved.

SUMMERY OF THE UTILITY MODEL

An object of the utility model is to provide a detect reagent box based on flow cytometry is through setting up magnetic ring one, tubulose membrane and magnetic ring two in the layer board to the use of cooperation shading lid realizes carrying out the shading with the test tube in the experimentation, has solved and has now before to flow cell detection, needs to carry out the light-resistant reaction to the sample, need put into other bigger boxes with the test-tube rack this moment, receives the problem of place restriction and difficult removal.

In order to solve the technical problem, the utility model discloses a realize through following technical scheme:

the utility model relates to a detection kit based on flow cytometry, which comprises a rectangular box body, wherein the top of the rectangular box body is connected with a supporting plate, and the end part of the supporting plate is connected with an outer cover in a matching way; the inner container of the box is detachably connected inside the rectangular box body; the supporting plate comprises a rectangular plate body, and convex edges I protruding towards the bottom are arranged on the periphery of the rectangular plate body; the rectangular plate body is provided with a plurality of through holes, and the upper surface of the rectangular plate body positioned on the periphery of any through hole is provided with a tubular surrounding edge; a first magnetic ring is fixed on the upper surface of the rectangular plate body on the peripheral side of the tubular surrounding edge, and one surface of the first fixed magnetic ring is connected with a second magnetic ring through a tubular film; when the test tube is used, the test tube penetrates through the through hole, the end part of the test tube is matched with the shading cover, and the shading cover is provided with the magnetic ring III matched with the magnetic ring II.

Furthermore, experimental equipment is placed in the inner container of the box, and the experimental equipment comprises a test tube and a reagent bottle.

Further, the tubular film is a black plastic film.

Furthermore, the upper surface of the rectangular plate body positioned on the peripheral sides of the through holes is provided with a second convex edge matched with the box outer cover.

Further, port department week of rectangle box body is provided with step portion one, the bottom of layer board be provided with step portion one complex step portion two.

Further, the light shielding cover comprises a substrate, and a convex tube capable of being inserted into a test tube port is arranged at the center of the substrate; and a rubber gasket is arranged on the base plate on the peripheral side of the convex pipe.

Further, the edge side of the rubber gasket is provided with a flange protruding upwards.

Further, the third magnetic ring is arranged on the peripheral side of the rubber gasket.

Furthermore, the side of the inner top of the outer cover of the box is provided with a rubber column or a rubber tube which is in sleeve joint with the convex tube.

Furthermore, the rectangular box body, the supporting plate and the box outer cover are made of light-tight materials which comprise light-tight plastics, wood plates and metal materials.

The utility model discloses following beneficial effect has:

the utility model realizes the shading of the test tube in the experimental process by arranging the magnetic ring I, the tubular membrane and the magnetic ring II in the supporting plate and matching with the shading cover, and the device has simple structure and convenient use; and can fix and shade test tubes of various different lengths and diameters.

Of course, it is not necessary for any particular product to achieve all of the above-described advantages at the same time.

Drawings

In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings used in the description of the embodiments will be briefly introduced below, and it is obvious that the drawings in the following description are only some embodiments of the present invention, and it is obvious for those skilled in the art that other drawings can be obtained according to these drawings without creative efforts.

FIG. 1 is a schematic view of the structure of the detection kit of the present invention;

FIG. 2 is a schematic view of a part of the structure of the detection kit of the present invention;

FIG. 3 is a schematic sectional view of the detection kit according to the present invention;

FIG. 4 is an enlarged view of a portion A of FIG. 3;

FIG. 5 is a schematic view of the rectangular box structure of the present invention;

FIG. 6 is a schematic view of the structure of the supporting plate of the present invention;

FIG. 7 is a schematic view of the structure of the outer cover of the box of the present invention;

fig. 8 is a schematic view of the structure of the light-shielding cover of the present invention.

Detailed Description

The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by a person of ordinary skill in the art without creative efforts belong to the protection scope of the present invention.

In the description of the present invention, it is to be understood that the terms "open hole", "upper", "lower", "thickness", "top", "middle", "length", "inner", "around", and the like, indicate positional or positional relationships, are merely for convenience in describing the present invention and to simplify the description, and do not indicate or imply that the components or elements referred to must have a particular orientation, be constructed and operated in a particular orientation, and therefore should not be construed as limiting the present invention.

Referring to fig. 1-8, the present invention relates to a flow cytometry-based assay kit, which comprises a rectangular box body 1, wherein the top of the rectangular box body 1 is connected with a support plate 3, and the end of the support plate 3 is connected with an outer cover 4; the rectangular box body 1 is detachably connected with an inner container 2; the supporting plate 3 comprises a rectangular plate body 31, wherein a convex edge 32 protruding towards the bottom is arranged on the peripheral side of the rectangular plate body 31; a plurality of through holes 30 are formed in the rectangular plate body 31, and a tubular surrounding edge 34 is arranged on the upper surface of the rectangular plate body 31 positioned on the periphery side of any through hole 30; the upper surface of the rectangular plate body 31 positioned on the periphery of the tubular surrounding edge 34 is fixed with a first magnetic ring 35, one surface of the first fixed magnetic ring 35 is connected with a second magnetic ring 37 through a tubular film 36, and the tubular film 36 is a black plastic film.

During the use, run through hole 30 with the test tube, and the tip cooperation of test tube is provided with shading lid 5, is provided with on shading lid 5 with the magnetic ring three 55 of magnetic ring two 37 complex, and shading lid 5 is located the tip of test tube this moment, and magnetic ring two 37 adsorbs to form on magnetic ring three 55 that black plastic film cover realizes the test tube shading in the week side of test tube.

Meanwhile, as shown in fig. 2, when the test tube box is used, the box liner 2 is taken out of the rectangular box body 1, the supporting plate 3 is assembled at the port in the rectangular box body 1, and the bottom of the test tube is contacted with the inner bottom side surface of the rectangular box body 1 at the moment. Through this setting, realize that this structure can fix and the shading to the test tube of multiple different length, diameter.

Experimental equipment is arranged in the box inner container 2, and the experimental equipment comprises a test tube and a reagent bottle. The rectangular box body 1, the supporting plate 3 and the box outer cover 4 are made of light-proof materials, and the light-proof materials comprise light-proof plastics, wood plates and metal materials.

The upper surface of the rectangular plate body 31 positioned on the periphery of the through holes 30 is provided with a first step part 11 matched with the outer box cover 4 along the periphery of the port of the rectangular box body 1 along a second convex edge 38, and the bottom end of the supporting plate 3 is provided with a second step part 33 matched with the first step part 11; the inner top side of the box outer cover 4 is provided with a rubber column or a rubber tube which is in sleeve fit with the convex tube 52.

The light shielding cover 5 comprises a base plate 51, and a convex tube 52 which can be inserted into the test tube port is arranged at the center of the base plate 51; a rubber gasket 53 is arranged on the base plate 51 positioned on the peripheral side of the convex pipe 52; the edge side of the rubber washer 53 is provided with a flange 54 projecting upward; the magnetic ring three 55 is arranged on the peripheral side of the rubber gasket 53.

In the description herein, references to the description of "one embodiment," "an example," "a specific example," etc., mean that a particular feature, structure, material, or characteristic described in connection with the embodiment or example is included in at least one embodiment or example of the invention. In this specification, the schematic representations of the terms used above do not necessarily refer to the same embodiment or example. Furthermore, the particular features, structures, materials, or characteristics described may be combined in any suitable manner in any one or more embodiments or examples.

The preferred embodiments of the present invention disclosed above are intended only to help illustrate the present invention. The preferred embodiments are not intended to be exhaustive or to limit the invention to the precise embodiments disclosed. Obviously, many modifications and variations are possible in light of the above teaching. The embodiments were chosen and described in order to best explain the principles of the invention and its practical applications, to thereby enable others skilled in the art to best understand the invention for and utilize the invention. The present invention is limited only by the claims and their full scope and equivalents.

Claims

1. A flow cytometry-based detection kit is characterized in that: comprises that

The box comprises a rectangular box body (1), wherein the top of the rectangular box body (1) is connected with a supporting plate (3), and the end part of the supporting plate (3) is connected with an outer box cover (4) in a matching way;

the rectangular box body (1) is detachably connected with a box inner container (2);

the supporting plate (3) body is a rectangular plate body (31), and the periphery of the rectangular plate body (31) extends to the bottom to form a first convex edge (32) matched with the box body;

the rectangular plate body (31) is provided with a plurality of through holes (30), and a tubular surrounding edge (34) is formed around each through hole (30); a first magnetic ring (35) is fixed on the upper surface of the rectangular plate body (31) positioned on the peripheral side of the tubular surrounding edge (34), and the upper surface of the first fixed magnetic ring (35) is connected with a second magnetic ring (37) through a tubular film (36);

and the shading cover (5) is provided with a magnetic ring III (55) matched with the magnetic ring II (37).

2. A flow cytometry-based detection kit according to claim 1, wherein experimental equipment is placed in the box inner container (2), and the experimental equipment comprises a test tube and a reagent bottle.

3. A flow cytometry-based detection kit as claimed in claim 1 wherein the tubular membrane (36) is a black plastic film.

4. A flow cytometry-based detection kit according to claim 1, wherein the upper surface of the rectangular plate (31) located on the periphery of the through hole (30) is provided with a protruding edge two (38) matched with the cartridge outer cover (4).

5. The flow cytometry-based detection kit according to claim 1, wherein a first step portion (11) is arranged on the periphery of the port of the rectangular box body (1), and a second step portion (33) matched with the first step portion (11) is arranged at the bottom end of the supporting plate (3).

6. A flow cytometry-based detection kit according to claim 1, wherein the light shielding cover (5) comprises a base plate (51), a convex tube (52) capable of being inserted into a test tube port is arranged at the center of the base plate (51);

and a rubber gasket (53) is arranged on the base plate (51) positioned on the peripheral side of the convex pipe (52).

7. A flow cytometry-based detection kit according to claim 6, wherein the rubber gasket (53) is provided at its edge side with an upwardly projecting bead (54).

8. A flow cytometry-based detection kit as claimed in claim 6 or 7 wherein the magnetic ring three (55) is disposed on the peripheral side of the rubber gasket (53).

9. A flow cytometry-based detection kit according to claim 6 or 7, wherein the inner top side surface of the outer box cover (4) is provided with a rubber column or a rubber tube which is sleeved and matched with the convex tube (52).

10. A flow cytometry-based detection kit according to claim 1, wherein the rectangular case (1), the support plate (3) and the case cover (4) are made of light-proof materials, and the light-proof materials comprise light-proof plastics, wood plates and metal materials.