CN216808825U - Transmission device and single cell sequencer comprising same - Google Patents
Transmission device and single cell sequencer comprising same Download PDFInfo
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- CN216808825U CN216808825U CN202123452757.9U CN202123452757U CN216808825U CN 216808825 U CN216808825 U CN 216808825U CN 202123452757 U CN202123452757 U CN 202123452757U CN 216808825 U CN216808825 U CN 216808825U
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Abstract
The utility model discloses a transmission device and a single cell sequencer comprising the same. The connecting component comprises a connecting rod, and the input end of the connecting component is connected with the output shaft of the power source; the sealing assembly is formed at the output end of the connecting assembly, and a sealing surface is formed on one side of the sealing assembly, which is deviated from the output end of the connecting assembly; the guide assembly comprises a moving member and a positioning member, the moving member is arranged at the output end of the connecting assembly, the positioning member is fixed relative to the power source, the positioning member comprises a containing cavity for the moving member to wear, the containing cavity extends along the direction perpendicular to the sealing surface, and the moving member is matched with the containing cavity. The spring that adopts when avoiding kick-backing is ageing, drives coupling assembling through the power supply and removes, and the direction subassembly is fixed a position coupling assembling, and coupling assembling's output drives seal assembly and lifts and push down.
Description
Technical Field
The utility model relates to a transmission device and a single cell sequencer comprising the same.
Background
The existing integrated single cell sequencer pressing device rebounds by compressing the spring when pressing, releases the spring when rising, and realizes lifting of the device by utilizing the elasticity of the spring, so that the spring has the risk of aging and failure after long-term use. Meanwhile, the number of samples in a single experiment of the conventional integrated single-cell sequencer is unique, and even if the number of samples can be changed, the integrated single-cell sequencer is realized by relatively complex operation and high cost.
SUMMERY OF THE UTILITY MODEL
The utility model aims to solve the technical problems that a single cell sequencer in the prior art is easy to fail and the number of samples in a single experiment is unique, and provides a transmission device and the single cell sequencer comprising the same.
The utility model solves the technical problems through the following technical scheme:
a transmission including a power source having a rotating output shaft, the transmission further comprising:
the connecting assembly comprises a connecting rod, and the input end of the connecting assembly is connected with the output shaft of the power source;
the sealing assembly is formed at the output end of the connecting assembly, and a sealing surface is formed on one side of the sealing assembly, which is far away from the output end of the connecting assembly;
the guide assembly, the guide assembly includes moving member and setting element, the moving member is established coupling assembling's output, the setting element is relative power source rigidity, the setting element is including supplying the chamber that holds that the moving member wore to establish, hold the chamber along the perpendicular to the direction of sealed face extends, the moving member with hold the chamber cooperation.
Among this technical scheme, the easy ageing problem of spring of adopting when avoiding kick-backing drives coupling assembling through the power supply and removes, and direction subassembly fixes a position coupling assembling, and coupling assembling's output drives seal assembly and lifts and push down. Coupling assembling does not have the ascending displacement of horizontal direction for the spring, therefore the sealed space that forms on the seal assembly can realize the increase of single experiment sample quantity, to the sample of the same quantity, can accelerate the experimental speed, reduces the experiment time, improves production efficiency, reduces the experiment cost, improves the reliability of instrument.
Preferably, the connecting assembly comprises three connecting rods, a first connecting rod is connected with the output shaft, a second connecting rod is rotatably connected with the first connecting rod, one end of a third connecting rod is rotatably connected with the second connecting rod, and the other end of the third connecting rod is connected with the sealing assembly.
In the technical scheme, as the kinematic pairs in the connecting rod mechanism are all low pairs in surface contact, the bearing pressure is small, the lubrication is convenient, the abrasion is light, and the bearing capacity is high. The components are simple in shape and convenient to process, and the contact between the components is kept by the geometrical constraint of the components, so that the components work reliably. The three sections of connecting rods can realize the conversion from the rotating motion to the moving motion.
Preferably, the first connecting rod and the second connecting rod, and the second connecting rod and the third connecting rod are connected through a bearing.
In the technical scheme, the bearing ensures the smoothness and no blockage when the connecting rod rotates.
Preferably, the transmission means comprises a gas circuit board detachably mounted on a face of the output end close to the seal assembly, and the seal face is formed on a face of the gas circuit board far from the output end.
In the technical scheme, the gas circuit board can be replaced, and the number of samples in a single experiment can be changed by upgrading the matched components. The sealed space is formed on the gas circuit board, and sealing can be realized.
Preferably, the seal assembly includes an adapter plate, and the adapter plate is arranged between a surface of the output end close to the gas circuit board and a surface of the gas circuit board close to the output end.
In the technical scheme, the adapter plate is combined with the gas circuit board and the output end to realize the connection of the gas circuit board and the output end.
Preferably, transmission includes the mount pad, be equipped with the through-hole on the mount pad, the power supply is established on the mount pad, coupling assembling wears out the through-hole.
In this technical scheme, the power supply is established on the mount pad, reserves coupling assembling's motion space.
Preferably, the sealing component comprises a screw, and the screw penetrates into the side face of the sealing component and abuts against the output end.
In this technical scheme, realize through the screw that seal assembly and coupling assembling's dismantlement are connected, conveniently change seal assembly.
Preferably, the sealing assembly and the output end of the connecting assembly are integrally formed.
In this technical scheme, directly adopt coupling assembling's output to seal, material saving, and can improve structural stability.
A single cell sequencer, the single cell sequencer comprising:
a transmission device;
the bearing piece is provided with a groove, the bearing piece comprises a sealing gasket, the sealing gasket is arranged between the bearing surface and the sealing surface, and a sealing space is formed between the surface of the sealing gasket facing the transmission device and the bearing surface.
In the technical scheme, the pressing device is adopted in the single cell sequencer, the risk of lifting failure of the pressing device can be solved, and the sealing space formed between the bearing piece and the transmission device can be used for sealing the microfluidic chip.
Preferably, the sealing gasket is made of silica gel or rubber.
In the technical scheme, sealing can be realized.
The positive progress effects of the utility model are as follows:
the problem that the spring that adopts when avoiding kick-backing is easily ageing drives coupling assembling through the power supply and removes, and direction subassembly fixes a position coupling assembling, and coupling assembling's output drives seal assembly and lifts and push down. The sealed space that forms on the seal assembly realizes the change of single experiment sample quantity, to the sample of the same quantity, can accelerate the experimental speed, reduces the experiment time, improves production efficiency, reduces the experiment cost, improves the reliability of instrument.
Drawings
Fig. 1 is an overall schematic view of a transmission according to an embodiment of the present invention.
Fig. 2 is another perspective overall view of the transmission device according to an embodiment of the utility model.
Fig. 3 is an isometric view of a transmission of one embodiment of the present invention.
Fig. 4 is a side view of a transmission according to an embodiment of the present invention.
Fig. 5 is a schematic structural diagram of a connecting assembly according to an embodiment of the utility model.
Fig. 6 is a schematic structural diagram of a sealing assembly according to an embodiment of the present invention.
Fig. 7 is a schematic structural diagram of a carrier according to an embodiment of the utility model.
Description of the reference numerals
A bearing member 200, a bearing surface 210
Connecting component 1, input end 11, output end 12, first connecting rod 13, second connecting rod 14, third connecting rod 15 and bearing 16
Sealing assembly 2, sealing face 21, gas circuit board 22, adapter plate 23, first screw 24, second screw 25, third screw 26
Guide assembly 3, moving member 31, positioning member 32, and accommodation chamber 33
Mounting seat 4, through hole 41 and sealing gasket 42
Detailed Description
The utility model is further illustrated by the following examples, which are not intended to limit the scope of the utility model.
As shown in fig. 1 and 2, the present invention discloses a transmission device, which includes a power source 100, the power source 100 having a rotating output shaft 110, a connecting assembly 1, a sealing assembly 2 and a guide assembly 3. The connecting assembly 1 comprises a connecting rod, an output shaft 110 of the power source 100 is connected with an input end 11 of the connecting assembly 1, and an output end 12 of the connecting assembly 1 is connected with the output shaft 110 of the power source 100. The sealing assembly 2 is formed at the output end 12 of the connecting assembly 1, and the side of the sealing assembly 2 facing away from the output end 12 of the connecting assembly 1 forms a sealing surface 21.
The guiding assembly 3 includes a moving member 31 and a positioning member 32, the moving member 31 is disposed at the output end 12 of the connecting assembly 1, the positioning member 32 is fixed with respect to the power source 100, the positioning member 32 includes a cavity 33 for the moving member 31 to penetrate, the cavity 33 extends along the direction perpendicular to the sealing surface 21, and the moving member 31 is matched with the cavity 33. The problem that the spring that adopts when avoiding kick-backing is easily ageing drives coupling assembling 1 through power supply 100 and removes, and direction subassembly 3 is fixed a position coupling assembling 1. The output end 12 of the connecting assembly 1 brings the sealing assembly 2 up and down. The output shaft 110 of the power source 100 rotates to drive the connecting component 1 to move, the connecting component 1 drives the sealing component 2 to lift up and press down, and the guide component 3 guides the connecting component 1 in the process, so that the sealing component 2 can lift up and press down relative to the microfluidic chip 300. Compare in the spring, coupling assembling 1 does not have the displacement on the horizontal direction, and consequently the sealed space that forms on the seal assembly 2 can realize the increase of single experiment sample quantity, to the sample of the same quantity, can accelerate the experimental speed, reduces the test time, improves production efficiency, reduces the experiment cost, improves the reliability of instrument.
As shown in fig. 1 and 2, the power source 100 employs a dc gear motor, which can reduce the rotation speed, and the dc gear motor rotates in one direction, thereby increasing the operation stability.
In other embodiments, seal assembly 2 and coupling assembling 1's output 12 can integrated into one piece, directly adopts coupling assembling 1's output 12 to seal, and material saving uses less part, reduces the assembly degree of difficulty, improves structural stability.
As shown in fig. 1 and 2, the connecting assembly 1 includes three links, a first link 13 is connected to the output shaft 110, a second link 14 is rotatably connected to the first link 13, one end of a third link 15 is rotatably connected to the second link 14, and the other end of the third link 15 is connected to the sealing assembly 2. As the kinematic pairs in the link mechanism are all low pairs in surface contact, the bearing pressure is small, the lubrication is convenient, the abrasion is light, and the bearing capacity is high. The components are simple in shape and convenient to process, and the contact between the components is kept by the geometrical constraint of the components, so that the components work reliably. The three sections of connecting rods can realize the conversion from the rotating motion to the moving motion.
In other embodiments, the connecting assembly 1 may include more than three links, which also allow the output end 12 of the link to travel in a direction perpendicular to the sealing surface 21.
As shown in fig. 1 and 2, the first link 13 and the second link 14, and the second link 14 and the third link 15 are connected by a bearing 16. The bearing 16 ensures that the connecting rod rotates smoothly and does not block.
In other embodiments, at least one of the first link 13 and the second link 14, and the second link 14 and the third link 15 may be connected by a polished rod. The polished rod connection can also realize the rotation of the connecting rod, and simultaneously, the process of arranging the bearing is avoided.
As shown in fig. 1 and 3, the actuator includes a gas circuit board 22, the gas circuit board 22 is detachably mounted on the face of the output end 12 close to the seal assembly 2, and the sealing face 21 is formed on the face of the gas circuit board 22 away from the output end 12. The gas circuit board 22 can be replaced, and the upgrade of the matched components can realize the change of the number of samples in a single experiment. The sealed space is formed on the gas path plate 22, and sealing can be achieved. In the operation process, the power source 100 drives the output shaft 110 to rotate to drive the connecting component 1, and the connecting component 1 drives the gas circuit board 22, so that the gas circuit board 22 is pressed down relative to the microfluidic chip 300. The seal assembly 2 includes an adapter plate 23, the adapter plate 23 being disposed between a face of the output end 12 adjacent the gas panel 22 and a face of the gas panel 22 adjacent the output end 12. The adapter plate 23 combines the gas panel 22 and the output 12.
As shown in fig. 1 and fig. 4, the transmission device includes a mounting base 4, a through hole 41 is provided on the mounting base 4, the power source 100 is provided on the mounting base 4, and the connecting component 1 penetrates through the through hole 41. The power source 100 is arranged on the mounting seat 4, and the movement space of the connecting component 1 can be reserved.
As shown in fig. 5 and 6, the sealing assembly 2 comprises a screw that penetrates the side of the sealing assembly 2, the screw abutting against the output end 12. The detachable connection of the sealing component 2 and the connecting component 1 is realized through screws, and the sealing component 2 is convenient to replace. The screws of the plurality of sides of the sealing member 2 are first screws 24 and second screws 25, respectively, and the screw penetrating the bottom surface of the sealing member 2 is a third screw 26. Through the screw of different angles, realize seal assembly 2's removable connection and stable fixed. When the air channel plate 22 is replaced, the air channel plate 22 can be taken out by screwing the first screw 24 and the second screw 25 and taking the air channel plate 22 away from the output end 12. The gas circuit board 22 can be removed and replaced by turning the third screw 26. The mounting step of the gas panel 22 is the reverse of the removal step.
As shown in fig. 1 and fig. 7, the present invention further discloses a single cell sequencer, which includes an actuator and a supporting member 200, wherein a supporting surface 210 is disposed on the supporting member 200 at a position facing the actuator, a groove (not shown) for supporting a sample is disposed on the supporting surface 210, a sealing space is formed between the sealing surface 21 of the sealing assembly 2 and the supporting surface 210, the supporting member 200 has a sealing gasket 42, a lower surface of the sealing gasket 42 is engaged with the microfluidic chip 300 in the groove of the supporting member 200, a surface of the gas channel plate 22 in the sealing assembly 2 facing the supporting member 200 is engaged with an upper surface of the sealing gasket 42, and the sealing of the microfluidic chip 300 is achieved by the sealing gasket 42. The material of the sealing gasket 42 is silica gel or rubber, which can realize sealing.
Example 2
The other parts of the transmission device disclosed in this embodiment are the same as those of embodiment 1, except that the connecting assembly is of a two-link structure (not shown in the figure), one end of the first link is connected to the rotation output shaft of the power source, and the other end of the first link is disposed in the kidney-shaped hole and connected to the second link. The second connecting rod is arranged in the waist-shaped hole, and the gas circuit board is connected with the second connecting rod, so that the rotation of the power source can be converted into movement by the two-connecting-rod structure.
While specific embodiments of the utility model have been described above, it will be appreciated by those skilled in the art that this is by way of example only, and that the scope of the utility model is defined by the appended claims. Various changes and modifications to these embodiments may be made by those skilled in the art without departing from the spirit and scope of the utility model, and these changes and modifications are within the scope of the utility model.
Claims (10)
1. A transmission including a power source having a rotating output shaft, the transmission further comprising:
the connecting assembly comprises a connecting rod, and the input end of the connecting assembly is connected with the output shaft of the power source;
the sealing assembly is formed at the output end of the connecting assembly, and a sealing surface is formed on one side of the sealing assembly, which is far away from the output end of the connecting assembly;
the guide assembly, the guide assembly includes moving member and setting element, the moving member is established coupling assembling's output, the setting element is relative power source rigidity, the setting element is including supplying the chamber that holds that the moving member wore to establish, hold the chamber along the perpendicular to the direction of sealed face extends, the moving member with hold the chamber cooperation.
2. The transmission of claim 1, wherein the coupling assembly includes three links, a first link coupled to the output shaft, a second link rotatably coupled to the first link, a third link rotatably coupled at one end to the second link, and a third link coupled at an opposite end to the seal assembly.
3. The transmission of claim 2, wherein the first link and the second link, and the second link and the third link are coupled by bearings.
4. The actuator of claim 1 including a gas panel removably mounted on a face of said output end adjacent said seal assembly, said seal face being formed on a face of said gas panel remote from said output end.
5. The transmission of claim 4, wherein the seal assembly includes an adapter plate disposed between a face of the output end adjacent the gas panel and a face of the gas panel adjacent the output end.
6. The transmission of claim 1, wherein the transmission includes a mounting base, a through hole is formed in the mounting base, the power source is arranged on the mounting base, and the connecting assembly penetrates through the through hole.
7. The transmission of claim 1, wherein the seal assembly includes a screw that penetrates a side of the seal assembly abutting the output end.
8. The transmission of claim 1, wherein the seal assembly and the output end of the coupling assembly are integrally formed.
9. A single cell sequencer, said single cell sequencer comprising:
the transmission of any one of claims 1-8;
the bearing piece is provided with a groove, the bearing piece comprises a sealing gasket, the sealing gasket is arranged between the bearing surface and the sealing surface, and a sealing space is formed between the surface of the sealing gasket facing the transmission device and the bearing surface.
10. The single cell sequencer of claim 9 wherein the gasket seal is made of silica gel or rubber.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202123452757.9U CN216808825U (en) | 2021-12-31 | 2021-12-31 | Transmission device and single cell sequencer comprising same |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202123452757.9U CN216808825U (en) | 2021-12-31 | 2021-12-31 | Transmission device and single cell sequencer comprising same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN216808825U true CN216808825U (en) | 2022-06-24 |
Family
ID=82060963
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202123452757.9U Active CN216808825U (en) | 2021-12-31 | 2021-12-31 | Transmission device and single cell sequencer comprising same |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN216808825U (en) |
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2021
- 2021-12-31 CN CN202123452757.9U patent/CN216808825U/en active Active
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| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20220831 Address after: Room 316, Building 1, No. 351, Guoshoujing Road, China (Shanghai) Pilot Free Trade Zone, Pudong New Area, Shanghai, 201203 Patentee after: Shanghai Mozhuo Biotechnology Co.,Ltd. Address before: 314501 No. 455 Heshun Road, Wuzhen Town, Tongxiang City, Jiaxing City, Zhejiang Province Patentee before: Mezhuo Biotechnology (Zhejiang) Co.,Ltd. |
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| TR01 | Transfer of patent right |