CN216747309U - Solution particle analyzer - Google Patents
Solution particle analyzer Download PDFInfo
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- CN216747309U CN216747309U CN202122771503.7U CN202122771503U CN216747309U CN 216747309 U CN216747309 U CN 216747309U CN 202122771503 U CN202122771503 U CN 202122771503U CN 216747309 U CN216747309 U CN 216747309U
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Abstract
The utility model discloses a solution particle analyzer. The solution particle analyzer includes: the system comprises a human-computer interaction unit, a processing control unit and an execution unit. The processing control unit is in communication connection with the man-machine interaction unit. The execution unit is in communication with the process control unit and includes a fluid pump, a sample platform, a light source, and an area-array camera controlled by the process control unit. The fluid pump can continuously pump the solution sample at the sample platform, the sample platform can adjust the lens focal length and the visual field of the area array camera under the control of the processing control unit, and the area array camera can acquire the image of the solution sample under the cooperation of the light source and transmit the image into the processing control unit for calculation and analysis. The solution particle analyzer improves efficiency and reduces errors.
Description
Technical Field
The utility model relates to the technical field of solution particle measurement; particularly, the utility model relates to a solution particle analyzer.
Background
According to different measurement requirements, various solution particle size measuring instruments widely used at present are various, and corresponding solution particle measuring methods are also various. The basic working principle of measurement can be divided into direct method and indirect method. Direct methods are based on geometric sizing of the particles, such as microscopy; the indirect method, such as sedimentation, electric induction, and light scattering, is to measure a certain physical quantity of a particle under the influence of certain factors, convert the measured physical quantity into a sphere diameter of the same physical quantity with the same value, and use the sphere diameter to represent the size of the particle.
In the instrument and the method, the direct method has complicated operation steps and low measurement efficiency; the indirect method cannot analyze single particles, is only suitable for detecting particles close to spherical shape, and has larger measurement error for non-spherical particles.
SUMMERY OF THE UTILITY MODEL
In view of the above, the present invention provides a solution particle analyzer that solves or at least alleviates one or more of the above technical problems and other problems associated with the prior art.
According to an aspect of the present invention, there is provided a solution particle analyzer, wherein the solution particle analyzer includes:
the human-computer interaction unit comprises input equipment and output equipment;
the processing control unit is in communication connection with the human-computer interaction unit, receives data from the input equipment and outputs information from the output equipment;
an execution unit communicatively coupled with the process control unit and including a fluid pump, a sample platform, a light source, and an area-array camera controlled by the process control unit,
the fluid pump can continuously pump the solution samples on the sample platform, the sample platform comprises a cross sliding table, and the area-array camera can acquire images of the solution samples under the cooperation of the light source and transmit the images to the processing control unit for calculation and analysis.
Optionally, in the solution particle analyzer as described above, the input device includes a keyboard, a touch screen and/or a mouse, and the output device includes a display.
Optionally, in the solution particle analyzer as described above, the processing control unit includes a central computing processor for acquiring images from the area-array camera and performing computational analysis.
Optionally, in the solution particle analyzer as described above, the process control unit includes a lower computer for controlling the execution unit.
Optionally, in the solution particle analyzer as described above, the area-array camera is hard-triggered by the lower computer or soft-triggered by the central computing processor.
Optionally, in the solution particle analyzer as described above, the sample platform is in the form of a cross slide.
Optionally, in the solution particle analyzer as described above, a position sensor is installed on the sample platform, and the position sensor feeds back a position signal of the sample platform to the lower computer to form closed-loop control.
Optionally, in the solution particle analyzer as described above, the light source is installed on an opposite side of the sample platform with respect to the area-array camera, the light source is a parallel light source, and the light source is a solid-color light source.
Optionally, in the solution particle analyzer as described above, the sample platform has a well bay for placing a sample well for sectioning the liquid sample pumped by the fluid pump from a sample bottle to a waste bottle.
Optionally, in the solution particle analyzer as described above, the processing control unit is installed with analysis processing software, and the analysis processing software has an operation display interface, an image acquisition and analysis algorithm.
The principles, features, characteristics, advantages, etc. according to the various aspects of the present invention will be clearly understood from the following detailed description taken in conjunction with the accompanying drawings. Adopt the utility model discloses a defect or not enough that exist in the current solution particle measuring instrument and method can be overcome or alleviated at least to the scheme, especially can improve measurement of efficiency, reduce detection error favorably.
Drawings
Other features of the present invention and advantages thereof will become more apparent from the following detailed description of exemplary embodiments thereof, which proceeds with reference to the accompanying drawings; it is to be understood, however, that the drawings are designed solely for the purposes of illustration and not as a definition of the limits of the invention. In the figure:
fig. 1 shows a schematic structural diagram of a solution particle analyzer according to an embodiment of the present invention; and
fig. 2 shows a block diagram of the solution particle analyzer of the embodiment of fig. 1.
Detailed Description
Exemplary embodiments of the present invention will be described in detail below with reference to the accompanying drawings. The components and structures in the drawings are merely schematic and are not necessarily to scale. It should be understood that the relative arrangement of parts and steps, etc., set forth in these embodiments, are illustrative only and are not intended to limit the scope of the present invention unless otherwise specifically indicated.
Furthermore, to any single feature described or implicit in the embodiments herein described or shown or implicit in the drawings or any single feature shown or implicit in the drawings, the present invention still allows any combination or addition or deletion to be continued between the features (or their equivalents) without any technical obstacles, so that further embodiments according to the present invention should be considered within the scope of this disclosure.
Fig. 1 shows a schematic structural diagram of a solution particle analyzer according to an embodiment of the present invention, which is applicable for analyzing particle size and shape of particles in a solution.
In the illustrated embodiment, it can be seen that the solution particle analyzer may include an upper computer 1, a lower computer 2, a sample platform 3, a light source 4, a light source controller 5, a fluid pump 6, and a lens camera module (including a lens 7 and an area-array camera 8). The sample platform 3 may be placed in a camera dark box 9 and a removable sample liquid reservoir 10 placed on the sample platform 3.
As shown in the drawing, in this embodiment, an upper computer 1 (i.e., a central computing processor) of the solution particle analyzer is provided at the lens camera module. According to this example, the lower computer 2 is also provided at the lens camera module. Specifically, the upper machine 1 is located at an upper portion, and the lower machine 2 is located at a lower portion. The design of the built-in central computing processor of the solution particle analyzer ensures that the system has better stability, and the complete machine has higher safety and operability by matching with a closed independent operating system. In other embodiments, the upper computer 1 and the lower computer 2 can be arranged at other positions according to specific conditions so as to adapt to different space requirements or other requirements.
The upper computer 1 and the lower computer 2 together may constitute a process control unit. The processing control unit can be provided with analysis software on the upper computer 1, the analysis software can be provided with an operation display interface, an image acquisition and analysis algorithm and the like, and can acquire and process images, analyze data and calculate parameters. These analysis algorithms may include, but are not limited to, preprocessing algorithms, contour extraction algorithms, acceleration optimization algorithms, standard parameter calculation algorithms, and the like.
According to the illustrated embodiment, the solution particle analyzer may further have a sample platform 3, and a well holder 11 for placing a sample well 10 may be provided on the sample platform 3. The sample liquid pool 10 is removable, and two ends thereof can be respectively connected with a sample bottle and a waste liquid bottle. The sample cell 10 may be a correspondingly designed device for passing a solution therethrough for imaging purposes, allowing the solution and the particles to be measured to pass through the device unimpeded, and allowing the thickness of the solution flowing through to be adjusted as necessary for analysis of particles of different sizes. Specifically, the liquid sample can continuously flow from the sample bottle to the waste liquid bottle 11 through the sample liquid pool 10 by the pumping action of the fluid pump 6. When the liquid sample with particles flows through the sample liquid pool 10, the camera 8 shoots the liquid sample with particles and transmits the shot image to the processing control unit, and the processing control unit analyzes and outputs the shot image.
In some embodiments, the fluid pump 6 may be selected as a high precision micro flow pump. The lower computer 2 can control the speed and the direction of the high-precision micro-flow pump. More specifically, the pump may be a volumetric pump capable of precise control of liquid flow rate and flow; and the liquid pump analyzed by the sample liquid pool can be added into the sample bottle for cycle analysis.
The sample platform 3 may comprise a cross slide, which may be, for example, a cross slide, having a substantially horizontal first slide and a substantially vertical second slide. The cross sliding table can adjust the lens focal length and the visual field of the area-array camera in two cross directions under the control of the processing control unit.
As shown in the figure, a light source 4 and a lens camera module are respectively disposed at both sides of a camera bellows 9. The light source 4 is mounted on the opposite side of the sample platform 3 relative to the area-array camera 8.
In the illustrated example, the light source 4 is disposed on the left side of the camera chamber 9, and may be a parallel light source or a pure color light source. The collimated light source may be exactly parallel to the central axis of the lens 7 and perpendicular to the plane of the liquid slice of the sample liquid cell 10. According to the specific situation, in different embodiments, these light sources may also be disposed on the right side of the camera dark box 9, and may include, but are not limited to, point light sources, line light sources, surface light sources, or diffuse reflection light sources. The light source controller 5 may be located nearby beside the light source 4. The lower computer 2 can drive the light source 4 to work by touching the light source controller 5, and can set parameters such as brightness, working mode and lighting time of the light source 4.
The lens camera module includes a lens 7 and a camera 8. The lens 7 can be a telecentric lens, and the camera 8 can be a high-resolution area-array camera; the use of other lenses and cameras is not excluded here. The high-resolution area-array camera can be triggered by a lower computer or an upper computer, so that a digital image imaged by the telecentric lens is acquired. The high-resolution area-array camera is matched with the high-precision micro-flow pump to continuously image flowing solution samples, so that a large number of samples can be rapidly analyzed, the shooting and measuring speed is obviously improved, and a large amount of time can be saved. In addition, the sample liquid pool 10 is used for constraining the solution into a continuous section shape which can be shot, and then a pure-color parallel light source and a telecentric lens are matched, so that the outline of sample particles in the solution can be truly restored, and the analysis accuracy is greatly improved.
Fig. 2 shows a block diagram of the solution particle analyzer of the embodiment of fig. 1.
As can be seen from the block diagram, in an alternative embodiment, the solution particle analyzer may further include a human-computer interaction unit. Specifically, the human-computer interaction unit can comprise an input device and an output device which are used as interfaces for operating the instrument and viewing the analysis result by a user. For example, but not limiting of, the input device may include a keyboard, a touch screen, and/or a mouse, etc., and the output device may include a display, etc. Other input-output devices are also possible.
In the case where the upper computer 1 and the lower computer 2 constitute a process control unit, the process control unit may be communicatively connected to a human-computer interaction unit, receive data from an input device, and output information from an output device. The upper computer 1 and the lower computer 2 may also be communicatively connected to each other.
The processing control unit can control the light source 4 (through the light source controller 5), the sample platform 3, the fluid pump 6, the camera 8 (such as an area-array camera) and other execution units through the lower computer 2.
Specifically, the lower computer 2 can be in communication connection with a light source controller 5, a cross sliding table of the sample platform 3, a fluid pump 6 and a camera 8, and then controls the light source 4 through the light source controller 5, controls the sample platform 3 through the cross sliding table, and the like.
In this embodiment, the camera 8 may be an area-array camera. The sample image shot by the area-array camera under the cooperation of the light source 4 can be transmitted to a processing control unit such as the upper computer 1 for calculation analysis and the like.
In alternative embodiments, the area-array camera may be triggered by the lower computer 2 or by the upper computer 1, so as to acquire digital images imaged through the optical lens 7. The use of the area-array camera improves the photographing efficiency compared to other photographing apparatuses in different embodiments. Particularly, the high-resolution area-array camera is matched with the high-precision cross sliding table, the first sliding table and the second sliding table of the cross sliding table are respectively and mechanically connected to the focal length adjusting system and the visual field adjusting system, the relative distance between the telecentric lens and the sample liquid pool can be controlled through the movement of the platform, so that the fine adjustment of the focal length is realized, and the visual field of the collected image can be controlled, so that the analysis of samples at different positions in the liquid pool is realized.
As described above, in the illustrated embodiment, the processing control unit may include the upper computer 1, i.e., the central computing processor, for acquiring images from the area-array camera and performing computational analysis, and may further include the lower computer 2 for controlling the respective execution units.
In an alternative embodiment, a position sensor (not shown) may also be mounted on the sample platform 3. The position sensor can feed back a position signal of the sample platform 3 to the lower computer 2 to form closed-loop control. The processing control unit can control each execution unit and collect position sensor signals through the lower computer 2.
The operation of the entire apparatus will be described below with reference to the solution particle analyzer of fig. 1 and 2. An operator holds a measured particle solution into a sample bottle, firstly determines a focusing and visual field range on a human-computer interaction interface, finishes flushing and sample introduction of a sample bottle, a sample liquid pool and a waste liquid bottle pipeline, starts measurement by one-key operation, controls a fluid pump by a lower computer to enable a sample to flow through the sample liquid pool at a preset speed and then enter the waste liquid bottle, and a high-resolution area-array camera images particles in the sample liquid pool through a telecentric lens under the coordination of a parallel light source until a preset sample amount is shot. The shot image is transmitted into a central computing processor, a series of preprocessing is carried out after the image is automatically subjected to phase plane calibration, then each particulate matter is identified and extracted by using a contour extraction algorithm, a series of standard parameters are calculated and analyzed by combining an optimization speed-up algorithm aiming at hardware and an operating system, and finally an analysis report is automatically generated and displayed to a user.
Some embodiments of a solution particle analyzer according to the present invention have been described above by way of example. Those skilled in the art will be able to make additions, deletions, or modifications to the embodiments and features therein without departing from the scope and spirit of the described embodiments. All equivalent technical solutions are intended to fall within the scope of the present invention and are considered to fall within the scope of the present invention.
List of reference numerals:
1 upper computer
2 lower machine
3 sample platform
4 light source
5 light source controller
6 fluid pump
7 lens
8 area-array camera
9 shooting camera bellows
10 sample liquid pool.
Claims (10)
1. A solution particle analyzer, comprising:
the human-computer interaction unit comprises input equipment and output equipment;
the processing control unit is in communication connection with the human-computer interaction unit, receives data from the input equipment and outputs information from the output equipment;
an execution unit communicatively connected with the process control unit and comprising a fluid pump (6), a sample platform (3), a light source (4) and an area array camera (8) controlled by the process control unit,
wherein the fluid pump (6) can continuously pump the solution sample at the sample platform (3), the sample platform (3) comprises a cross sliding table, and the area-array camera (8) can acquire the image of the solution sample under the cooperation of the light source (4) and transmit the image into the processing control unit for calculation and analysis.
2. The solution particle analyzer of claim 1, wherein the input device comprises a keyboard, a touch screen, and/or a mouse, and the output device comprises a display.
3. The solution particle analyzer of claim 1, wherein the process control unit comprises a central computing processor for acquiring images from the area-array camera and performing computational analysis.
4. The solution particle analyzer according to claim 3, wherein the process control unit includes a lower computer (2) for controlling the execution unit.
5. The solution particle analyzer according to claim 4, wherein the area-array camera (8) is hard-triggered by the lower computer (2) or soft-triggered by the central computing processor.
6. The solution particle analyzer according to claim 4, wherein the sample platform (3) is in the form of a cross slide.
7. The solution particle analyzer according to claim 6, wherein a position sensor is mounted on the sample platform (3), and the position sensor feeds back a position signal of the sample platform (3) to the lower computer (2) to form a closed-loop control.
8. The solution particle analyzer according to claim 1, wherein the light source (4) is mounted on the opposite side of the sample platform (3) with respect to the area-array camera (8), the light source (4) is a collimated light source, and the light source (4) is a pure color light source.
9. The solution particle analyzer according to claim 1, wherein the sample platform (3) has a well holder for holding a sample well (10), the sample well (10) slicing a liquid sample pumped by the fluid pump (6) from a sample bottle to a waste bottle.
10. The solution particle analyzer of claim 1, wherein said process control unit has analytical process software installed thereon, said analytical process software having an operation display interface, an image acquisition and analysis algorithm.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202122771503.7U CN216747309U (en) | 2021-11-12 | 2021-11-12 | Solution particle analyzer |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202122771503.7U CN216747309U (en) | 2021-11-12 | 2021-11-12 | Solution particle analyzer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN216747309U true CN216747309U (en) | 2022-06-14 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN202122771503.7U Active CN216747309U (en) | 2021-11-12 | 2021-11-12 | Solution particle analyzer |
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| CN (1) | CN216747309U (en) |
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2021
- 2021-11-12 CN CN202122771503.7U patent/CN216747309U/en active Active
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