CN216653739U - Product precipitation equipment in system for producing and processing bulk drugs - Google Patents
Product precipitation equipment in system for producing and processing bulk drugs Download PDFInfo
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- CN216653739U CN216653739U CN202122484961.2U CN202122484961U CN216653739U CN 216653739 U CN216653739 U CN 216653739U CN 202122484961 U CN202122484961 U CN 202122484961U CN 216653739 U CN216653739 U CN 216653739U
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/10—Process efficiency
Abstract
The utility model discloses product precipitation equipment in a system for producing and processing raw material medicines, which comprises a bottom plate, wherein a main centrifugal machine is arranged on one side of the top end of the bottom plate, a first material rotating pump is arranged on the top end of the bottom plate on one side of the main centrifugal machine, a material storage tank is arranged on one side of the top end of the bottom plate, a material supply pipe is arranged on the top end of the material storage tank, one end of the material supply pipe is connected with the first material rotating pump, a material guide pipe is arranged on one side of the bottom end of the material storage tank, a nano filter is arranged on one side of the top end of the bottom plate, one end of the nano filter is connected with the material guide pipe, a return pipe is arranged on the outer wall on one side of the nano filter, and a switch valve is arranged on one side of the surface of the return pipe. The utility model not only meets the requirements of products with high chemical activity and poor thermal stability, effectively reduces impurities in the products, promotes full reaction of materials, improves the precipitation quality of the products, but also reduces the heat loss of equipment and reduces the use cost of the equipment.
Description
Technical Field
The utility model relates to the technical field of production of raw material medicines, in particular to product precipitation equipment in a raw material medicine production and processing system.
Background
At present, the solvent is removed by adopting a steam heating and normal pressure or reduced pressure distillation mode in the production process of the raw material medicine so as to achieve the purpose of separating out the product in the system.
The vacuum distillation device of the solicin bulk drug disclosed in the publication No. CN212119073U comprises a base, wherein a mixing box with a hollow structure is fixedly installed at the top of the base, a filter box with a hollow structure is fixedly installed at the top of the base, the same fixing plate is fixedly installed on the inner walls of the two sides of the mixing box, a rotating groove is formed in the top of the fixing plate, a rotating column is rotatably installed in the rotating groove, the mixing efficiency of the solicin bulk drug is improved, the solicin bulk drug is more uniformly mixed, impurities in the solicin bulk drug can be filtered by vibrating an annular filter plate, but the problems that the existing device consumes a large amount of steam, the temperature rise in the distillation process is rapid, the device is not friendly to some products with high chemical activity and poor thermal stability, impurities are easily generated, and the stirring performance of the existing device is poor, the materials are difficult to fully react, the preparation quality of the product is reduced, and therefore a raw material medicine product precipitation device is provided.
SUMMERY OF THE UTILITY MODEL
The utility model aims to provide product precipitation equipment in a system for producing and processing bulk drugs, and aims to solve the problems that the equipment provided in the background technology is not friendly to products with high chemical activity and poor thermal stability, is easy to generate impurities and has insufficient product reaction.
In order to achieve the purpose, the utility model provides the following technical scheme: a product precipitation device in a system for producing and processing bulk drugs comprises a bottom plate, wherein a main centrifugal machine is installed on one side of the top end of the bottom plate, a first material transferring pump is installed on the top end of the bottom plate on one side of the main centrifugal machine, a material storage tank is installed on one side of the top end of the bottom plate, a material feeding pipe is installed on the top end of the material storage tank, one end of the material feeding pipe is connected with the first material transferring pump, a material guide pipe is installed on one side of the bottom end of the material storage tank, a nano filter is installed on one side of the top end of the bottom plate, one end of the nano filter is connected with the material guide pipe, a return pipe is installed on the outer wall of one side of the nano filter, a switch valve is installed on one side of the surface of the return pipe, one end of the return pipe extends to the inside of the material storage tank, a second material transferring pump is installed on one side of the top end of the bottom plate, and the input end of the second material transferring pump extends to the inside of the nano filter, the reaction kettle is characterized in that a reaction kettle main body is installed on one side of the top end of the bottom plate, a third material transferring pump is installed at the bottom end of the reaction kettle main body, and an auxiliary centrifugal machine is installed at the top end of the bottom plate on one side of the reaction kettle main body.
Preferably, one side of the bottom end of the nano-filter is provided with a liquid outlet, and a nano-filtration membrane is arranged in the nano-filter.
Preferably, one side on reation kettle main part top is fixed with the backplate, just the surface mounting of backplate has the motor, the pivot is installed to the output of motor, and the bottom of pivot extends to the inside of reation kettle main part.
Preferably, the inner wall of the reaction kettle main body is provided with an inner container, a liquid storage tank is arranged between the inner container and the reaction kettle main body, and the outer wall of the inner container is fixedly provided with a baffle ring.
Preferably, install the feed liquor valve on the outer wall of reation kettle main part one side, install the tapping valve on the opposite side outer wall of reation kettle main part, the winding has the heater strip on the outer wall of inner bag one side.
Preferably, a stirring rod is fixed on one side of the surface of the rotating shaft, and an arc-shaped stirring paddle is fixed at the end part of the stirring rod.
Compared with the prior art, the utility model has the beneficial effects that: the product precipitation equipment in the system for producing and processing the bulk drugs not only meets the requirements of products with high chemical activity and poor thermal stability, effectively reduces impurities in the products, promotes full reaction of materials, improves precipitation quality of the products, but also reduces heat loss of the equipment and use cost of the equipment;
(1) through a structure with matching of a material guide pipe, a reaction kettle main body and the like, mother liquor enters a nano filter through the material guide pipe, a product is filtered and purified by a nano filtering membrane, a liquid outlet is a filtered solvent, a concentrated feed liquid is filtered out from an upper outlet, the concentrated feed liquid is pumped into a reaction kettle of the reaction kettle main body by using a second material transferring pump to be collected and reacted, frozen saline is introduced into a jacket of the reaction kettle main body to promote the product to be separated out, the product is pumped into a secondary centrifuge through a third material transferring pump to be centrifuged after being separated out, the obtained product is packaged and warehoused after being detected to be qualified, and the solvent escapes through the aperture between membranes;
(2) through the arrangement of the matched structures such as the stirring rods and the arc-shaped stirring paddles, a worker starts the motor through the control end to work, the motor sequentially drives the rotating shaft and the stirring rods to rotate, the arc-shaped stirring paddles connected between the stirring rods can fully mix materials in the reaction kettle main body, the existence of material mixing blind areas is reduced, the materials are fully reacted, and the precipitation quality of products is improved;
(3) through being provided with complex structures such as feed liquor valve and heater strip, inject the conduction oil into the inside of reservoir through the feed liquor valve, utilize the conduction oil to keep warm to the inner bag for the heater strip can reduce thermal loss when the heating, reduces the use cost of equipment promptly.
Drawings
FIG. 1 is a schematic front view of the present invention;
FIG. 2 is a schematic structural view of a main body of a reaction vessel according to the present invention;
FIG. 3 is a schematic structural diagram of a front cross-section of a nanofilter according to the present invention;
FIG. 4 is an enlarged view of the structure at A in FIG. 2 according to the present invention;
in the figure: 1. a base plate; 2. a primary centrifuge; 3. a first material transfer pump; 4. a feed pipe; 5. a material storage tank; 6. a material guide pipe; 7. a nano-filter; 701. a liquid discharge port; 702. a nanofiltration membrane; 8. a return pipe; 801. an on-off valve; 9. a second material transferring pump; 10. a reaction kettle main body; 11. a third material transferring pump; 12. a secondary centrifuge; 13. a back plate; 14. a motor; 15. a rotating shaft; 16. a stirring rod; 17. an arc-shaped stirring paddle; 18. an inner container; 19. a tapping valve; 20. a baffle ring; 21. heating wires; 22. a liquid storage tank; 23. and a liquid inlet valve.
Detailed Description
The technical solution in the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present invention. All other embodiments, which can be obtained by a person skilled in the art without making any creative effort based on the embodiments in the present invention, belong to the protection scope of the present invention.
Referring to fig. 1-4, an embodiment of the present invention is shown: a product precipitation device in a system for producing and processing bulk drugs comprises a bottom plate 1, a main centrifugal machine 2 is installed on one side of the top end of the bottom plate 1, a first material transferring pump 3 is installed on the top end of the bottom plate 1 on one side of the main centrifugal machine 2, a material storage tank 5 is installed on one side of the top end of the bottom plate 1, a material feeding pipe 4 is installed on the top end of the material storage tank 5, one end of the material feeding pipe 4 is connected with the first material transferring pump 3, a material guide pipe 6 is installed on one side of the bottom end of the material storage tank 5, a nano-filtering machine 7 is installed on one side of the top end of the bottom plate 1, one end of the nano-filtering machine 7 is connected with the material guide pipe 6, a return pipe 8 is installed on the outer wall of one side of the nano-filtering machine 7, a switch valve 801 is installed on one side of the surface of the return pipe 8, a liquid discharge port 701 is installed on one side of the bottom end of the nano-filtering machine 7, a nano-filtering membrane 702 is installed inside the nano-filtering machine 2, mother liquid spun and filtered by the main centrifugal machine is pumped into the material storage tank 5 for temporary storage, after a certain amount of the raw materials are collected, the raw materials are pumped into a nano filter 7 through a material guide pipe 6;
the nano-filtration membrane 702 is used for intercepting macromolecular substances in the solution, and the solvent escapes through the pore diameter between the membranes, so that the concentration of the product in the system is improved, and the product can be obtained through the traditional recrystallization mode after cooling;
one end of the return pipe 8 extends to the inside of the material storage tank 5, one side of the top end of the bottom plate 1 is provided with a second material transferring pump 9, the input end of the second material transferring pump 9 extends to the inside of the nano filter 7, one side of the top end of the bottom plate 1 is provided with a reaction kettle main body 10, one side of the top end of the reaction kettle main body 10 is fixedly provided with a back plate 13, the surface of the back plate 13 is provided with a motor 14, the output end of the motor 14 is provided with a rotating shaft 15, the bottom end of the rotating shaft 15 extends to the inside of the reaction kettle main body 10, one side of the surface of the rotating shaft 15 is fixedly provided with a stirring rod 16, and the end part of the stirring rod 16 is fixedly provided with an arc-shaped stirring paddle 17;
the motor 14 sequentially drives the rotating shaft 15 and the stirring rods 16 to rotate, and at the moment, the arc-shaped stirring paddles 17 connected between the stirring rods 16 can fully mix materials in the reaction kettle main body 10, so that the existence of material mixing blind areas is reduced, the materials are fully reacted, and the precipitation quality of products is improved;
an inner container 18 is mounted on the inner wall of the reaction kettle main body 10, a liquid storage tank 22 is arranged between the inner container 18 and the reaction kettle main body 10, a baffle ring 20 is fixed on the outer wall of the inner container 18, a liquid inlet valve 23 is mounted on the outer wall of one side of the reaction kettle main body 10, a liquid discharge valve 19 is mounted on the outer wall of the other side of the reaction kettle main body 10, and a heating wire 21 is wound on the outer wall of one side of the inner container 18;
heat conduction oil is injected into the liquid storage tank 22 through the liquid inlet valve 23, and the heat conduction oil is utilized to keep the temperature of the inner container 18, so that the heat loss can be reduced when the heating wire 21 is heated, namely the use cost of the equipment is reduced;
the bottom of reation kettle main part 10 is installed third commentaries on classics material pump 11, nano-filter 7 divide into two exports, drain port 701 is the solvent that filters out, detect qualified back direct reuse in this workshop section, it is the feed liquid after the concentration to go up the export filtration, utilize second commentaries on classics material pump 9 to pump it into reation kettle main part 10 reation kettle and collect and react, the cover of reation kettle main part 10 is pressed from both sides and is let in frozen salt solution and impel the product to precipitate, and the vice centrifuge 12 is installed on the bottom plate 1 top of reation kettle main part 10 one side, the product is precipitated and is gone into in the vice centrifuge 12 to centrifuge through third commentaries on classics material pump 11 pump, the product that obtains is detected qualified and is packed and put in storage.
When the device is used, firstly, mother liquor thrown and filtered by a main centrifugal machine 2 is pumped into a storage tank 5 through a first material transferring pump 3 for temporary storage, after being collected to a certain amount, the mother liquor is pumped into a nano-filtering machine 7 through a material guide pipe 6, the nano-filtering machine 7 is divided into two outlets, a liquid discharge port 701 is a filtered solvent, the solvent is directly reused in the working section after being detected to be qualified, the material liquid filtered out from the upper outlet is concentrated, the concentrated material liquid is pumped into a reaction kettle main body 10 through a second material transferring pump 9 for collection and reaction, frozen saline water is introduced into a jacket of the reaction kettle main body 10 to promote product precipitation, the product is pumped into an auxiliary centrifugal machine 12 through a third material transferring pump 11 for centrifugation after being precipitated, the obtained product is packaged and warehoused after being detected to be qualified, macromolecular substances are intercepted in the solution through a nano-filtering membrane 702, the solvent escapes through the aperture between the membranes, the concentration of the product in the system is improved, the product can be obtained through the traditional recrystallization mode after cooling, and compared with the traditional steam heating mode, the solvent is removed through the normal pressure or reduced pressure distillation mode, the consumption of the steam can be reduced through the mode, the product with high chemical activity and poor thermal stability is met, and the impurities in the product are reduced.
Claims (6)
1. A product precipitation device in a system for producing and processing bulk drugs is characterized in that: comprises a bottom plate (1), a main centrifugal machine (2) is installed on one side of the top end of the bottom plate (1), a first material transferring pump (3) is installed on the top end of the bottom plate (1) on one side of the main centrifugal machine (2), a material storage tank (5) is installed on one side of the top end of the bottom plate (1), a material supply pipe (4) is installed on the top end of the material storage tank (5), one end of the material supply pipe (4) is connected with the first material transferring pump (3) mutually, a material guide pipe (6) is installed on one side of the bottom end of the material storage tank (5), a nano-filter (7) is installed on one side of the top end of the bottom plate (1), one end of the nano-filter (7) is connected with the material guide pipe (6) mutually, a return pipe (8) is installed on the outer wall of one side of the nano-filter (7), a switch valve (801) is installed on one side of the surface of the return pipe (8), one end of the return pipe extends to the inside of the material storage tank (5), the second is installed on one side on bottom plate (1) top and is changeed material pump (9), and the input that the second changes material pump (9) extends to the inside of nano-filter (7), reation kettle main part (10) are installed to one side on bottom plate (1) top, and third commentaries on classics material pump (11) are installed to the bottom of reation kettle main part (10), just vice centrifuge (12) are installed on bottom plate (1) top of reation kettle main part (10) one side.
2. The device for separating out a product in a system for producing and processing a raw material medicament according to claim 1, which is characterized in that: a liquid discharge port (701) is installed on one side of the bottom end of the nano-filter (7), and a nano-filtration membrane (702) is installed inside the nano-filter (7).
3. The device for separating out a product in a system for producing and processing a raw material medicament according to claim 1, which is characterized in that: one side on reation kettle main part (10) top is fixed with backplate (13), just the surface mounting of backplate (13) has motor (14), pivot (15) are installed to the output of motor (14), and the bottom of pivot (15) extends to the inside of reation kettle main part (10).
4. The device for separating out a product in a system for producing and processing a raw material medicament according to claim 1, which is characterized in that: the inner wall of the reaction kettle main body (10) is provided with an inner container (18), a liquid storage tank (22) is arranged between the inner container (18) and the reaction kettle main body (10), and the outer wall of the inner container (18) is fixedly provided with a baffle ring (20).
5. The device for separating out a product in a system for producing and processing a raw material drug according to claim 4, characterized in that: install feed liquor valve (23) on the outer wall of reation kettle main part (10) one side, install bleeder valve (19) on the opposite side outer wall of reation kettle main part (10), the winding has heater strip (21) on the outer wall of inner bag (18) one side.
6. The product separation device in the system for producing and processing the bulk drug according to claim 3, characterized in that: one side on pivot (15) surface is fixed with puddler (16), just the tip of puddler (16) is fixed with arc stirring rake (17).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202122484961.2U CN216653739U (en) | 2021-10-15 | 2021-10-15 | Product precipitation equipment in system for producing and processing bulk drugs |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202122484961.2U CN216653739U (en) | 2021-10-15 | 2021-10-15 | Product precipitation equipment in system for producing and processing bulk drugs |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN216653739U true CN216653739U (en) | 2022-06-03 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202122484961.2U Active CN216653739U (en) | 2021-10-15 | 2021-10-15 | Product precipitation equipment in system for producing and processing bulk drugs |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN216653739U (en) |
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2021
- 2021-10-15 CN CN202122484961.2U patent/CN216653739U/en active Active
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