CN216425402U - Freezing storage box - Google Patents

Abstract

There is provided a cryopreservation box configured to receive a cryopreservation bag, comprising: a box including a bottom, first and second opposing sides, and third and fourth opposing sides; the box cover is hinged with one end of the third side part and one end of the fourth side part, which is close to the first side part, and can rotate to be overlapped with the second side part so as to cover the box body; and the locking cover is hinged to the second side part and provided with a clamping groove, the locking cover can be parallel to the bottom and rotate to an opening state and a locking state, the locking cover is not interfered with the box cover in the opening state, the box body and the box cover covering the box body are clamped into the clamping groove. This disclosed technical scheme can promote the convenience of the structural reliability and the operation of freezing the case.

Description

Freezing storage box

Technical Field

The disclosure relates to the technical field of biological medicines, in particular to a freezing storage box.

Background

With the development of biomedical technology, cell therapy is rapidly developing worldwide. The cell therapy is fundamentally the acquisition and storage of living cells, and in order to preserve the cells and enable the cells to have biological activity for a long time, the freezing and recovery of the cells become a crucial link. The preparation and storage of cells, especially the low-temperature storage and recovery conditions of biological samples such as umbilical cord blood, stem cells and the like, and the prevention of pollution in the operation process are important subjects of the current clinical application of cell therapy.

The related art process for freezing and storing cell sap comprises the following steps: placing the freezing bag filled with the cell sap into a freezing box; then, arranging a plurality of freezing boxes on the freezing support; then, the cryopreserved scaffold was placed in a liquid nitrogen tank, whereby the cell fluid was cryopreserved in the liquid nitrogen tank. The cryopreservation box is a device for storing the cryopreservation bag, and the reliability of the structure and the convenience of operation directly affect the reliable storage of the cell sap in the cryopreservation bag, so that the cryopreservation box is a key content which is paid attention to by the technical personnel in the field.

SUMMERY OF THE UTILITY MODEL

The embodiment of the disclosure provides a freezing storage box, so as to improve the structural reliability and the operation convenience of the freezing storage box.

The embodiment of the present disclosure provides a freezing storage box, including: a box including a bottom, first and second opposing sides, and third and fourth opposing sides; the box cover is hinged with one end of the third side part and one end of the fourth side part, which is close to the first side part, and can rotate to be overlapped with the second side part so as to cover the box body; and the locking cover is hinged to the second side part and provided with a clamping groove, the locking cover can be parallel to the bottom and rotate to an opening state and a locking state, the locking cover is not interfered with the box cover in the opening state, the box body and the box cover covering the box body are clamped into the clamping groove.

In some embodiments, the cryopreservation cartridge is configured to be placed longitudinally and in a forward orientation on the cryopreservation stand; the third side is located the upside of freezing case, and fourth side is located the downside of freezing case, and the lid has the window that is close to the third side and keeps away from the fourth side and offers, and the window configuration is for revealing the melt-seal structure of freezing bag.

In some embodiments, the first side portion is located on a left side of the cryopreservation box, the second side portion is located on a right side of the cryopreservation box, and the locking cover is hinged to an upper end of the second side portion.

In some embodiments, the lid includes a body portion and a projection portion on a side of the body portion remote from the first side portion, the latch lid is in the latched state, and the box body and the projection portion are snapped into the snap groove.

In some embodiments, the body portion and the projection have a first relief therebetween, and the base portion and the second side portion have a second relief therebetween; the locking cover comprises a first wall part, a second wall part and a third wall part which are sequentially connected and form a clamping groove, wherein when the locking cover is in a locking state, the first wall part is stopped at the first convex mark, and the third wall part is stopped at the second convex mark.

In some embodiments, the second side portion includes a fourth wall portion, a fifth wall portion, and a sixth wall portion connected in series and forming a groove, wherein the fourth wall portion is connected to the bottom portion.

In some embodiments, the lid further comprises a first folded wall portion, a second folded wall portion and a third folded wall portion connected to the body portion, the first folded wall portion being located outside the third side portion, the second folded wall portion being located outside the fourth side portion, and the third folded wall portion being located outside the first side portion when the lid is closed to the body.

In some embodiments, the cryopreservation box further comprises: and the shock pad is positioned in the box body and is matched with the outline shape of the cryopreservation bag.

In some embodiments, the cryopreservation box further comprises: and the label is attached to the surface of the box cover.

In some embodiments, the cryopreservation box further comprises: the freezing box is made of aluminum or stainless steel.

According to this cryopreserved box of one or more embodiments of the disclosure, open and lock the cryopreserved box through the bottom forward or the reverse rotation with the locking closure parallel to the box body, the operation is very convenient, and moreover, the locking closure is at the locking state, and in box body and lid card income draw-in groove, the lid can not be opened because of unexpected touching basically, consequently, the structural reliability of cryopreserved box is preferred.

These and other aspects of the disclosure will be apparent from and elucidated with reference to the embodiments described hereinafter.

Drawings

Further details, features and advantages of the disclosure are disclosed in the following description of exemplary embodiments, taken in conjunction with the accompanying drawings, in which:

fig. 1 is a perspective view of a cryopreservation box according to some exemplary embodiments of the present disclosure (with the locking lid in an open state);

fig. 2 is a schematic front view of a cryopreservation box according to some exemplary embodiments of the present disclosure (the locking lid is in a closed state);

fig. 3 is a front view schematic of a cryopreservation box according to some exemplary embodiments of the present disclosure (with the locking lid in an open state); and

fig. 4 is a rear view schematic of a cryopreservation box according to some exemplary embodiments of the present disclosure (with the locking lid in a closed state).

Description of reference numerals:

100-freezing and storing the box;

1-freezing and storing bags;

101-a melt sealing structure;

2-box body;

201-a first side;

202-a second side;

203-a third side;

204-a fourth side;

205-bottom;

206-a second bump;

207-fourth wall portion;

208-a fifth wall portion;

209-sixth wall portion;

3-a box cover;

301-a body portion;

302-a projection;

303-third folded wall section;

304-a first folded wall portion;

305-a second folded portion;

306-a window;

307-first embossment;

4-locking the cover;

401-a first wall portion;

402-a second wall portion;

403-a third wall portion;

404-card slot;

5-a shock pad; and

6-label.

Detailed Description

In the following, only certain exemplary embodiments are briefly described. As those skilled in the art can appreciate, the described embodiments can be modified in various different ways, without departing from the spirit or scope of the present disclosure. Accordingly, the drawings and description are to be regarded as illustrative in nature, and not as restrictive.

The freezing storage box is used as a device for storing the freezing storage bag, and the reliability of the structure and the convenience of operation directly influence the reliable storage of the cell sap in the freezing storage bag. The embodiment of the disclosure provides a freezing storage box, so as to improve the structural reliability and the operation convenience of the freezing storage box.

As shown in fig. 1, 2, 3 and 4, some embodiments of the present disclosure provide a cryopreservation box 100 comprising a box body 2, a box cover 3 and a locking cover 4, wherein the box body 2 comprises a bottom 205, first and second opposite sides 201 and 202, and third and fourth opposite sides 203 and 204. The lid 3 is hinged (e.g. by rivets) to the third 203 and fourth 204 sides near the first side 201 and can be rotated to overlap the second side 202 to close the box 2. The locking cover 4 is hinged (e.g. hinged by a rivet) to the second side 202 and has a locking groove 404, the locking cover 4 can rotate parallel to the bottom 205 to an open state and a locked state, the locking cover 4 does not interfere with the box cover 3 in the open state, the locking cover 4 is in the locked state, and the box body 2 and the box cover 3 covering the box body 2 are clamped in the locking groove 404.

The material type of the freezing storage box 100 is not limited, for example, aluminum material or stainless steel material can be used, and the main structure is formed by sheet metal process.

According to the technical scheme of the embodiment of the disclosure, the freezing storage box 100 is opened and locked by forwardly or reversely rotating the locking cover 4 parallel to the bottom 205 of the box body 2, the operation is very convenient, and the locking cover 4 is in a locking state, the box body 2 and the box cover 3 are clamped into the clamping groove 404, and the box cover 3 is basically not opened due to accidental touch, so that the freezing storage box 100 is good in structural reliability.

In clinical application of cell therapy, the process of cryopreserving cell sap includes: placing the cryopreservation bag 1 filled with the cell sap into a cryopreservation box 100 in a mode that a fusion sealing structure 101 faces upwards; then, a plurality of the freezing storage boxes 100 are arranged on the freezing storage support, and each freezing storage box 100 is placed longitudinally and positively to keep the sealing structure 101 upward; then, the cryopreserved scaffold was placed in a liquid nitrogen tank, whereby the cell fluid was cryopreserved in the liquid nitrogen tank.

In some embodiments of the present disclosure, the cryopreservation cartridge 100 is placed on the cryopreservation rack in the longitudinal and forward direction. In this set state of the cryopreservation box 100, the third side 203 is located on the upper side of the cryopreservation box 100, the fourth side 204 is located on the lower side of the cryopreservation box 100, the box cover 3 has a window 306 opened close to the third side 203 and far from the fourth side 204, and the window 306 is configured to expose the sealing structure 101 of the cryopreservation bag 1.

Through the window 306, whether the cryopreservation bag 1 is placed in the forward direction can be conveniently judged. For example, if the window 306 exposes the sealing structure 101 of the frozen bag 1, it can be determined that the frozen bag 1 is placed in the forward direction, and if the window 306 does not expose the sealing structure 101 of the frozen bag 1, it can be determined that the frozen bag 1 is placed in the upside down direction. The design of window 306 on the one hand can play the effect of preventing slow-witted, and on the other hand also is convenient for observe the sealed condition of freezing bag 1.

As shown in fig. 2, the cryopreservation box 100 further comprises a label 6 attached to the outer surface of the box cover 3. The specific location of the tab 6 is not limited, and may be, for example, below the window 306 as shown in the figure. The information contained on the label 6 is not specifically limited in the present disclosure, and may include, for example, bar code or two-dimensional code information corresponding to the cryopreservation box 100, bar code or two-dimensional code information corresponding to the cryopreservation bag 1, composition of the contents of the cryopreservation bag 1, indication, property, specification, contraindication, storage condition, usage amount, adverse reaction, caution item, manufacturer, production lot number, production date, quality guarantee date, and the like.

As shown in fig. 4, the box cover 3 further includes a first folded wall portion 304, a second folded wall portion 305 and a third folded wall portion 303 connected to the body portion 301, wherein when the box cover 3 is covered on the box body 2, the first folded wall portion 304 is located outside the third side portion 203, the second folded wall portion 305 is located outside the fourth side portion 204, and the third folded wall portion 303 is located outside the first side portion 201. The cryopreserving box 100 is supported by each lateral part of box body 2 and each wall portion of lid 3 jointly in the thickness direction for cryopreserving box 100's structural strength is higher, can provide more reliable protection to the cryopreserving bag 1 that inside held.

As shown in fig. 1, the cryopreservation box 100 further comprises a shock pad 5 which is positioned in the box body 2 and is approximately matched with the outline shape of the cryopreservation bag 1. The shock absorbing pad 5 is, for example, a rubber shock absorbing pad 5, a foam shock absorbing pad 5, a cardboard shock absorbing pad 5, or the like, and the specific material type thereof is not limited. The shock pad 5 can play the shock attenuation effect, can avoid freezing when depositing the box 100 accident and fall causing the fish tail to freezing bag 1, is favorable to stabilizing the state of freezing the interior cell liquid of bag 1. The shape of the shock pad 5 is approximately matched with the outline shape of the cryopreservation bag 1, so that the cryopreservation bag 1 can be prevented from being placed reversely, a good supporting and shock absorbing effect can be achieved on the cryopreservation bag 1, and displacement or deformation of the cryopreservation bag 1 in the cryopreservation box 100 can be reduced as much as possible.

As shown in fig. 1, 2 and 3, in some embodiments of the present disclosure, the first side 201 is located on the left side of the cryopreservation box 100, the second side 202 is located on the right side of the cryopreservation box 100, and the locking lid 4 is hinged with the upper end of the second side 202.

Referring to the illustration in the figure, the locking cover 4 needs to be rotated counterclockwise around the top end of the second side portion 202 to open the locking cover 4, and the locking cover 4 needs to be rotated clockwise around the top end of the second side portion 202 to lock the locking cover 4. This design can make the rotational operation of the locking lid 4 comparatively handy (comply with the right-hand operation), and moreover, the freezing storage box 100 is in a longitudinal and forward placement state, and because the locking lid 4 has a certain weight, the locking lid 4 can be prevented from being opened accidentally. This design further enhances the structural reliability and operational convenience of the cryopreservation cartridge 100.

As shown in fig. 1, 2, 3 and 4, the box cover 3 includes a main body 301 and a protrusion 302 located on a side of the main body 301 away from the first side 201, and when the locking cover 4 is in a locked state, the box body 2 and the protrusion 302 are clamped into the clamping groove 404.

As can be seen, a notch is formed on each side of the projection 302. This design only need go into the draw-in groove 404 of locking closure 4 with the bulge 302 card of box body 2 and lid 3, can lock the cryopreserved box 100, the operation of being convenient for more on the one hand, it is comparatively laborsaving to operate, and on the other hand can avoid leading to the locking closure 4 can't lock in place or receive great frictional force because of reasons such as manufacturing error or deformation, and on the other hand, can also alleviate the weight of cryopreserved box 100.

In some embodiments, as shown in fig. 1, 2 and 4, the body 301 and the protrusion 302 of the box cover 3 have a first convex mark 307 therebetween, and the bottom 205 and the second side 202 of the box body 2 have a second convex mark 206 therebetween; the locking cover 4 includes a first wall portion 401, a second wall portion 402 and a third wall portion 403 which are connected in sequence and form a card slot, and when the locking cover 4 is in a locking state, the first wall portion 401 is stopped at the first convex mark 307, and the third wall portion 403 is stopped at the second convex mark 206.

This scheme structural design can make the locking closure 4 accurately reach the locking state, can not lead to the structure to destroy because of rotation angle is too big, has further promoted the structural reliability of freezing box 100.

It will be understood that in this specification, the terms "center," "longitudinal," "lateral," "length," "width," "thickness," "upper," "lower," "front," "rear," "left," "right," "vertical," "horizontal," "top," "bottom," "inner," "outer," "clockwise," "counterclockwise," "axial," "radial," "circumferential," and the like, indicate an orientation or positional relationship or dimension based on that shown in the drawings, which terms are used for convenience of description only and do not indicate or imply that the device or element being referred to must have a particular orientation, be constructed and operated in a particular orientation, and therefore should not be considered limiting to the scope of the disclosure.

Furthermore, the terms "first," "second," "third," and the like are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or to implicitly indicate the number of technical features indicated. Thus, features defined as "first", "second", and "third" may explicitly or implicitly include one or more of the features. In the description of the present disclosure, "a plurality" means two or more unless specifically limited otherwise.

In the present disclosure, unless otherwise expressly stated or limited, the terms "mounted," "connected," "secured," and the like are to be construed broadly and can, for example, be fixedly connected, detachably connected, or integral; the connection can be mechanical connection, electrical connection or communication; either directly or indirectly through intervening media, either internally or in any other relationship. The specific meaning of the above terms in the present disclosure can be understood by those of ordinary skill in the art as appropriate.

In the present disclosure, unless expressly stated or limited otherwise, the first feature "on" or "under" the second feature may comprise the first and second features being in direct contact, or may comprise the first and second features being in contact, not directly, but via another feature in between. Also, the first feature being "on," "above" and "over" the second feature includes the first feature being directly on and obliquely above the second feature, or merely indicating that the first feature is at a higher level than the second feature. A first feature being "under," "below," and "beneath" a second feature includes the first feature being directly under and obliquely below the second feature, or simply meaning that the first feature is at a lesser elevation than the second feature.

This description provides many different embodiments or examples that can be used to implement the present disclosure. It should be understood that these various embodiments or examples are purely exemplary and are not intended to limit the scope of the disclosure in any way. Those skilled in the art can conceive of various changes or substitutions based on the disclosure of the specification of the present disclosure, which are intended to be included within the scope of the present disclosure. Therefore, the protection scope of the present disclosure should be subject to the protection scope defined by the appended claims.

Claims (10)

1. A cryopreservation cartridge configured to receive a cryopreservation bag, comprising:

a box including a bottom, first and second opposing sides, and third and fourth opposing sides;

the box cover is hinged with one end of the third side part and one end of the fourth side part, which is close to the first side part, and can rotate to be overlapped with the second side part so as to cover the box body; and

the locking closure is articulated and has the draw-in groove with the second side, and the locking closure can be on a parallel with the bottom and rotate to open mode and locking state, and the locking closure does not have the interference at open mode and lid, and the locking closure is at locking state, and the box body fits in the lid card of box body and goes into in the draw-in groove.

2. The cryopreservation box of claim 1,

the cryopreservation box is configured to be placed on the cryopreservation bracket longitudinally and positively;

the third side is located the upside of freezing case, and fourth side is located the downside of freezing case, and the lid has the window that is close to the third side and keeps away from the fourth side and offers, and the window configuration is for revealing the melt-seal structure of freezing bag.

3. The cryopreservation box of claim 2, wherein the first side portion is located at a left side of the cryopreservation box, the second side portion is located at a right side of the cryopreservation box, and the locking cover is hinged with an upper end of the second side portion.

4. The cryopreservation box of claim 1,

the lid includes body portion and the bulge that is located the one side of keeping away from first lateral part of body portion, and the locking closure is in the locking state, and box body and bulge card are gone into in the draw-in groove.

5. The cryopreservation cartridge of claim 4,

a first convex mark is arranged between the body part and the protruding part, and a second convex mark is arranged between the bottom part and the second side part;

the locking cover comprises a first wall part, a second wall part and a third wall part which are sequentially connected and form a clamping groove, wherein when the locking cover is in a locking state, the first wall part is stopped at the first convex mark, and the third wall part is stopped at the second convex mark.

6. The cryopreservation box of claim 4, wherein the second side portion comprises a fourth wall portion, a fifth wall portion and a sixth wall portion which are connected in sequence and form a groove, wherein the fourth wall portion is connected with the bottom portion.

7. The cryopreservation box of claim 1,

the box cover further comprises a first folding wall portion, a second folding wall portion and a third folding wall portion, wherein the first folding wall portion, the second folding wall portion and the third folding wall portion are connected with the body portion, when the box cover is covered on the box body, the first folding wall portion is located on the outer side of the third side portion, the second folding wall portion is located on the outer side of the fourth side portion, and the third folding wall portion is located on the outer side of the first side portion.

8. The cryopreservation box of claim 1, further comprising:

and the shock pad is positioned in the box body and is matched with the outline shape of the cryopreservation bag.

9. The cryopreservation cartridge of claim 1, further comprising:

and the label is attached to the surface of the box cover.

10. The cryopreservation box of any one of claims 1 to 9, wherein the cryopreservation box is an aluminium or stainless steel cryopreservation box.

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